Guido Kroemer
#13,642
Most Influential Person Now
Molecular biologist
Guido Kroemer's AcademicInfluence.com Rankings
Guido Kroemerbiology Degrees
Biology
#335
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#604
Historical Rank
Molecular Biology
#31
World Rank
#31
Historical Rank
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Biology
Guido Kroemer's Degrees
- PhD Molecular Biology University of Geneva
- Doctorate Medicine University of Geneva
Why Is Guido Kroemer Influential?
(Suggest an Edit or Addition)According to Wikipedia, Guido Kroemer is a cell biologist who has made contributions to the understanding of the role of mitochondria in cell death. He is a member of multiple scientific academies in Europe and is one of the most highly cited authors in cell biology.
Guido Kroemer's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Hallmarks of Aging (2013) (9261)
- Autophagy in the Pathogenesis of Disease (2008) (6420)
- Molecular characterization of mitochondrial apoptosis-inducing factor (1999) (4165)
- Mitochondrial membrane permeabilization in cell death. (2007) (3372)
- The Pathophysiology of Mitochondrial Cell Death (2004) (3298)
- Self-eating and self-killing: crosstalk between autophagy and apoptosis (2007) (3214)
- Mitochondrial control of cell death (2000) (3146)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors (2018) (3049)
- Autophagy and the integrated stress response. (2010) (2966)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 (2005) (2802)
- Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy (2007) (2668)
- Calreticulin exposure dictates the immunogenicity of cancer cell death (2007) (2495)
- Classification of cell death: recommendations of the Nomenclature Committee on Cell Death (2005) (2403)
- Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008) (2360)
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011) (2295)
- Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota (2015) (2213)
- Immunogenic cell death in cancer therapy. (2013) (2210)
- The mitochondrial death/life regulator in apoptosis and necrosis. (1998) (2079)
- Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
- Molecular mechanisms of necroptosis: an ordered cellular explosion (2010) (2045)
- Tumor cell metabolism: cancer's Achilles' heel. (2008) (2036)
- Molecular mechanisms of cisplatin resistance (2012) (1979)
- Autophagy and Aging (2011) (1807)
- Self-consumption: the interplay of autophagy and apoptosis (2014) (1675)
- Inhibition of Macroautophagy Triggers Apoptosis (2005) (1662)
- Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death (1995) (1619)
- Immunogenic cell death in cancer and infectious disease (2016) (1609)
- Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors (2009) (1606)
- Organelle-specific initiation of cell death pathways (2001) (1467)
- Mitochondrial control of nuclear apoptosis (1996) (1431)
- Targeting mitochondria for cancer therapy (2010) (1422)
- The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide (2013) (1421)
- Autophagic cell death: the story of a misnomer (2008) (1405)
- Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death (2001) (1396)
- The immune contexture in cancer prognosis and treatment (2017) (1295)
- Biological Functions of Autophagy Genes: A Disease Perspective (2019) (1287)
- Induction of autophagy by spermidine promotes longevity (2009) (1280)
- Cancer despite immunosurveillance: immunoselection and immunosubversion (2006) (1252)
- Bcl-2 inhibits the mitochondrial release of an apoptogenic protease (1996) (1236)
- Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo (1995) (1230)
- Cell death by mitotic catastrophe: a molecular definition (2004) (1201)
- Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. (1998) (1196)
- Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death (2005) (1162)
- Lysosomes and autophagy in cell death control (2005) (1156)
- Lysosomal membrane permeabilization in cell death (2008) (1154)
- Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice (2011) (1141)
- Functional and physical interaction between Bcl‐XL and a BH3‐like domain in Beclin‐1 (2007) (1132)
- Regulation of autophagy by cytoplasmic p53 (2008) (1097)
- Regulation of autophagy by cytoplasmic p53 (2008) (1097)
- The mitochondrion in apoptosis: how Pandora's box opens (2001) (1096)
- [Mitochondrial control of apoptosis]. (2001) (1094)
- Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents. (2015) (1062)
- The biochemistry of programmed cell death (1995) (1061)
- Cell death by necrosis: towards a molecular definition. (2007) (1045)
- Cytoplasmic functions of the tumour suppressor p53 (2009) (1037)
- Mechanisms of cytochrome c release from mitochondria (2006) (1036)
- Molecular definitions of autophagy and related processes (2017) (1036)
- The proto-oncogene Bcl-2 and its role in regulating apoptosis (1997) (1033)
- Immunogenic and tolerogenic cell death (2009) (986)
- Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging (2011) (985)
- Hsp27 negatively regulates cell death by interacting with cytochrome c (2000) (964)
- Current development of mTOR inhibitors as anticancer agents (2006) (945)
- Autophagy in malignant transformation and cancer progression (2015) (941)
- The proto-oncogene Bcl-2 and its role in regulating apoptosis (1997) (914)
- Mitochondrial permeability transition is a central coordinating event of apoptosis (1996) (909)
- The molecular machinery of regulated cell death (2019) (904)
- Immunogenic death of colon cancer cells treated with oxaliplatin (2010) (877)
- Heat shock proteins: endogenous modulators of apoptotic cell death. (2001) (864)
- Heat-shock protein 70 antagonizes apoptosis-inducing factor (2001) (864)
- Mitochondria as regulators of apoptosis: doubt no more. (1998) (858)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Caspase-independent cell death (2005) (809)
- Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis (2000) (799)
- Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
- The central executioners of apoptosis: caspases or mitochondria? (1998) (793)
- Acetyl coenzyme A: a central metabolite and second messenger. (2015) (791)
- Type I interferons in anticancer immunity (2015) (789)
- Two Distinct Pathways Leading to Nuclear Apoptosis (2000) (785)
- Immunological aspects of cancer chemotherapy (2008) (785)
- Tumor cells convert immature myeloid dendritic cells into TGF-β–secreting cells inducing CD4+CD25+ regulatory T cell proliferation (2005) (778)
- Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process (1999) (769)
- Cell death modalities: classification and pathophysiological implications (2007) (749)
- Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy (2014) (746)
- The Permeability Transition Pore Complex: A Target for Apoptosis Regulation by Caspases and Bcl-2–related Proteins (1998) (735)
- Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. (2013) (705)
- Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors. (2016) (704)
- Mitotic catastrophe: a mechanism for avoiding genomic instability (2011) (696)
- Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets. (1997) (695)
- Decoding cell death signals in liver inflammation. (2013) (692)
- Metabolic Control of Autophagy (2014) (678)
- Cardioprotection and lifespan extension by the natural polyamine spermidine (2016) (676)
- Mitochondrial metabolism and cancer (2017) (675)
- Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy. (2016) (675)
- The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis (1997) (672)
- Mechanisms of pre‐apoptotic calreticulin exposure in immunogenic cell death (2009) (671)
- Ferroptosis: molecular mechanisms and health implications (2020) (670)
- Broadening horizons: the role of ferroptosis in cancer (2021) (661)
- Heat Shock Proteins 27 and 70: Anti-Apoptotic Proteins with Tumorigenic Properties (2006) (658)
- Macrophages and Metabolism in the Tumor Microenvironment. (2019) (636)
- Consensus guidelines for the detection of immunogenic cell death (2014) (634)
- The secret ally: immunostimulation by anticancer drugs (2012) (626)
- Mitochondria: master regulators of danger signalling (2012) (616)
- Immune parameters affecting the efficacy of chemotherapeutic regimens (2011) (610)
- AIF deficiency compromises oxidative phosphorylation (2004) (597)
- Systems biology of cisplatin resistance: past, present and future (2014) (590)
- The anticancer immune response: indispensable for therapeutic success? (2008) (579)
- Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles (2017) (571)
- Bcl-2 family members: Dual regulators of apoptosis and autophagy (2008) (553)
- Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis (2008) (543)
- Mitochondrion as a novel target of anticancer chemotherapy. (2000) (542)
- Decoding Cell Death Signals in Inflammation and Immunity (2010) (540)
- Inflammasomes in carcinogenesis and anticancer immune responses (2012) (538)
- Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells. (2013) (534)
- The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death (2005) (532)
- Metabolic targets for cancer therapy (2013) (531)
- The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy (2007) (525)
- Targeting the tumor microenvironment: removing obstruction to anticancer immune responses and immunotherapy. (2016) (523)
- Metabolic control of cell death (2014) (521)
- Necroptosis: A Specialized Pathway of Programmed Necrosis (2008) (520)
- Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy (2010) (519)
- Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death (1999) (515)
- Mitochondria and programmed cell death: back to the future (1996) (510)
- Cell death assays for drug discovery (2011) (510)
- Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death? (2002) (510)
- The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death (1997) (508)
- Metabolic Control of Longevity (2016) (508)
- Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death (2002) (501)
- Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria. (2002) (497)
- Spermidine in health and disease (2018) (494)
- Mitochondria, the killer organelles and their weapons (2002) (488)
- Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects. (2016) (476)
- The HIV-1 Viral Protein R Induces Apoptosis via a Direct Effect on the Mitochondrial Permeability Transition Pore (2000) (474)
- Autophagy regulation by p53. (2010) (472)
- Apoptosis‐inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis (2000) (472)
- Does Autophagy Contribute To Cell Death? (2005) (466)
- Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis (1996) (461)
- Apoptosis in yeast: triggers, pathways, subroutines (2010) (456)
- The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity. (2017) (452)
- Cathepsin D Triggers Bax Activation, Resulting in Selective Apoptosis-inducing Factor (AIF) Relocation in T Lymphocytes Entering the Early Commitment Phase to Apoptosis* (2003) (449)
- A novel dendritic cell subset involved in tumor immunosurveillance (2006) (448)
- The microbiome in cancer immunotherapy: Diagnostic tools and therapeutic strategies (2018) (444)
- BH3-Only Proteins and BH3 Mimetics Induce Autophagy by Competitively Disrupting the Interaction between Beclin 1 and Bcl-2/Bcl-XL (2007) (442)
- Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion (2003) (442)
- Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins (1998) (439)
- Calreticulin exposure is required for the immunogenicity of γ-irradiation and UVC light-induced apoptosis (2007) (433)
- Consensus guidelines for the definition, detection and interpretation of immunogenic cell death (2020) (423)
- Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome (2011) (421)
- Molecular characteristics of immunogenic cancer cell death (2008) (417)
- Control of autophagy by oncogenes and tumor suppressor genes (2009) (416)
- Immunostimulation with chemotherapy in the era of immune checkpoint inhibitors (2020) (412)
- Autophagy and Mitophagy in Cardiovascular Disease. (2017) (410)
- Mitochondrial Control of Cellular Life, Stress, and Death (2012) (407)
- Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition (2013) (406)
- The mitochondrion in cell death control: certainties and incognita. (2000) (405)
- Chemotherapy: targeting the mitochondrial cell death pathway (2002) (403)
- Can autophagy promote longevity? (2010) (402)
- NADH Oxidase Activity of Mitochondrial Apoptosis-inducing Factor* (2001) (397)
- Viral Control of Mitochondrial Apoptosis (2008) (397)
- An AIF orthologue regulates apoptosis in yeast (2004) (394)
- Regulation of autophagy by cytosolic acetyl-coenzyme A. (2014) (387)
- Targeted Deletion of AIF Decreases Mitochondrial Oxidative Phosphorylation and Protects from Obesity and Diabetes (2007) (386)
- Mitochondrial membrane permeabilization in neuronal injury (2009) (382)
- Ferroptosis is a type of autophagy-dependent cell death. (2020) (381)
- Necroptosis: Mechanisms and Relevance to Disease. (2017) (380)
- Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine (2003) (378)
- Anti- and pro-tumor functions of autophagy. (2009) (366)
- A dual role for autophagy in a murine model of lung cancer (2014) (366)
- Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid* (1998) (365)
- Prognostic and predictive impact of intra- and peritumoral immune infiltrates. (2011) (361)
- Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance. (2016) (361)
- The hallmarks of successful anticancer immunotherapy (2018) (361)
- Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis. (1996) (360)
- Classification of current anticancer immunotherapies (2014) (357)
- Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator (2000) (353)
- An Immunosurveillance Mechanism Controls Cancer Cell Ploidy (2012) (352)
- Autophagy and cellular immune responses. (2013) (350)
- DNA binding is required for the apoptogenic action of apoptosis inducing factor (2002) (345)
- Essential role for autophagy in life span extension. (2015) (345)
- Platelet formation is the consequence of caspase activation within megakaryocytes. (2002) (345)
- GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization (2007) (342)
- Mitochondrial control of apoptosis. (1997) (341)
- Molecular mechanisms of ATP secretion during immunogenic cell death (2013) (341)
- Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe (2002) (340)
- Mitochondrial Implication in Accidental and Programmed Cell Death: Apoptosis and Necrosis (1997) (340)
- Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death (2012) (339)
- Mitochondria as therapeutic targets for cancer chemotherapy (2006) (337)
- Dendritic cell-derived exosomes for cancer therapy. (2016) (336)
- AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc – Activity (2018) (335)
- Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1 (2015) (333)
- Complex Inhibitory Effects of Nitric Oxide on Autophagy (2011) (331)
- Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress (2011) (327)
- Regulation of autophagy by the inositol trisphosphate receptor (2007) (327)
- Regulation of autophagy by the inositol trisphosphate receptor (2007) (327)
- Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene (2009) (326)
- Cancer and the gut microbiota: An unexpected link (2015) (326)
- Anticancer effects of the microbiome and its products (2017) (324)
- Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore. (1999) (324)
- Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria (2002) (324)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- Apoptosis-inducing factor: vital and lethal. (2006) (323)
- Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents. (1997) (322)
- Extracellular vesicles: masters of intercellular communication and potential clinical interventions. (2016) (322)
- Mitochondrial control of apoptosis: an introduction. (2003) (319)
- A dual role of p53 in the control of autophagy (2008) (319)
- Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect (2013) (319)
- Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis. (1997) (317)
- Targeting PD-1/PD-L1 interactions for cancer immunotherapy (2012) (316)
- Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1 (2010) (316)
- Immunogenic cancer cell death: a key-lock paradigm. (2008) (315)
- Mitochondria--the Death Signal Integrators (2000) (313)
- The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death (2008) (312)
- Tumor cell death and ATP release prime dendritic cells and efficient anticancer immunity. (2010) (312)
- Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential. (2019) (311)
- Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors (2011) (309)
- Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy (2004) (303)
- Immunogenic Tumor Cell Death for Optimal Anticancer Therapy: The Calreticulin Exposure Pathway (2010) (302)
- The gut microbiota influences anticancer immunosurveillance and general health (2018) (302)
- Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing (2018) (300)
- Alternative cell death mechanisms in development and beyond. (2010) (299)
- Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transition (1998) (298)
- Microbiome and Anticancer Immunosurveillance (2016) (297)
- Apoptosis and genomic instability (2004) (296)
- IL-18 induces PD-1-dependent immunosuppression in cancer. (2011) (296)
- Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis (2000) (296)
- Expression of P2X7 receptor increases in vivo tumor growth. (2012) (295)
- Involvement of apoptosis‐inducing factor in neuronal death after hypoxia‐ischemia in the neonatal rat brain (2003) (292)
- The IKK complex contributes to the induction of autophagy (2010) (290)
- The IKK complex contributes to the induction of autophagy (2010) (290)
- Control of Mitochondrial Membrane Permeabilization by Adenine Nucleotide Translocator Interacting with HIV-1 Viral Protein R and Bcl-2 (2001) (289)
- Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition (2014) (289)
- Identification of an infectious progenitor for the multiple-copy HERV-K human endogenous retroelements. (2006) (288)
- Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death (2015) (287)
- The end of autophagic cell death? (2012) (282)
- The spectrum of T cell metabolism in health and disease (2017) (282)
- Autophagy in major human diseases (2021) (282)
- Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis. (2018) (278)
- Autophagy: a druggable process that is deregulated in aging and human disease. (2015) (278)
- Stimulation of autophagy by the p53 target gene Sestrin2 (2009) (276)
- The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1 (2009) (276)
- To die or not to die: that is the autophagic question. (2008) (275)
- Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor (2003) (274)
- Bcl-2 family members: dual regulators of apoptosis and autophagy. (2008) (274)
- AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis (2004) (273)
- The tumor suppressor protein p53 and the ferroptosis network (2019) (272)
- Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. (2003) (270)
- miR-181a and miR-630 regulate cisplatin-induced cancer cell death. (2010) (269)
- PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. (1998) (267)
- Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy (2011) (267)
- Quantitation of mitochondrial alterations associated with apoptosis. (2002) (266)
- Mutant p53 protein localized in the cytoplasm inhibits autophagy (2008) (265)
- Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors. (2013) (263)
- HSP27 and HSP70: Potentially Oncogenic Apoptosis Inhibitors (2003) (262)
- Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells. (1998) (260)
- Trial watch: IDO inhibitors in cancer therapy (2014) (260)
- A comprehensive glossary of autophagy-related molecules and processes (2nd edition) (2011) (259)
- High-mobility group box 1 is essential for mitochondrial quality control. (2011) (259)
- Dominant cell death induction by extramitochondrially targeted apoptosis‐inducing factor (2001) (258)
- Caspases Connect Cell-Death Signaling to Organismal Homeostasis. (2016) (257)
- Nitric oxide induces apoptosis via triggering mitochondrial permeability transition (1997) (256)
- A comprehensive glossary of autophagy-related molecules and processes (2010) (253)
- The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal (2001) (252)
- No death without life: vital functions of apoptotic effectors (2008) (252)
- Mitochondrial gateways to cancer. (2010) (252)
- Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution (1997) (250)
- Combinatorial Strategies for the Induction of Immunogenic Cell Death (2015) (250)
- Autophagy-Dependent Ferroptosis: Machinery and Regulation. (2020) (249)
- Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice (2019) (248)
- Crosstalk between apoptosis and autophagy within the Beclin 1 interactome (2010) (247)
- Mitochondrial permeability transition triggers lymphocyte apoptosis. (1996) (246)
- Chemotherapy induces ATP release from tumor cells (2009) (246)
- Nutrition, inflammation and cancer (2017) (246)
- Natural and therapy-induced immunosurveillance in breast cancer (2015) (245)
- Linking cellular stress responses to systemic homeostasis (2018) (243)
- Pharmacological manipulation of cell death: clinical applications in sight? (2005) (243)
- First oncolytic virus approved for melanoma immunotherapy (2016) (241)
- Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis (2001) (239)
- Vital functions for lethal caspases (2005) (239)
- Detection of immunogenic cell death and its relevance for cancer therapy (2020) (238)
- Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator (2000) (236)
- Mouse models in oncoimmunology (2016) (234)
- Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy (2017) (233)
- Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity. (2012) (232)
- Apoptosis-inducing factor (AIF): caspase-independent after all (2004) (230)
- Tumor cells can escape DNA‐damaging cisplatin through DNA endoreduplication and reversible polyploidy (2008) (228)
- Mammalian Target of Rapamycin (mTOR): Pro- and Anti-Apoptotic (2002) (228)
- Regulation of autophagy by stress-responsive transcription factors. (2013) (225)
- Apoptosis Control in Syncytia Induced by the HIV Type 1–Envelope Glycoprotein Complex (2000) (223)
- Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein (2020) (221)
- Trial Watch—Oncolytic viruses and cancer therapy (2016) (221)
- Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. (1996) (221)
- Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan (2014) (220)
- Redox regulation of apoptosis: Impact of thiol oxidation status on mitochondrial function (1997) (219)
- Transmission of innate immune signaling by packaging of cGAMP in viral particles (2015) (219)
- Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis. (2009) (218)
- The mitochondrial pathway in yeast apoptosis (2007) (218)
- Methods for the assessment of mitochondrial membrane permeabilization in apoptosis (2007) (214)
- Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies. (2008) (213)
- Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes. (1998) (213)
- Molecular mechanisms of regulated necrosis. (2014) (213)
- Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia (2007) (212)
- Functional Characterization of Negri Bodies (NBs) in Rabies Virus-Infected Cells: Evidence that NBs Are Sites of Viral Transcription and Replication (2009) (211)
- Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore (1999) (211)
- Immunoendocrine communication via the hypothalamo-pituitary-adrenal axis in autoimmune diseases. (1993) (211)
- Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses (2020) (210)
- Organelle-specific initiation of cell death (2014) (208)
- DNA Damage in Stem Cells. (2017) (207)
- Clockophagy is a novel selective autophagy process favoring ferroptosis (2019) (207)
- Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy (2015) (207)
- Immunogenic cell death modalities and their impact on cancer treatment (2009) (206)
- Autophagy in healthy aging and disease (2021) (205)
- Programmed mitophagy is essential for the glycolytic switch during cell differentiation (2017) (205)
- Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia (2007) (205)
- Spermidine induces autophagy by inhibiting the acetyltransferase EP300 (2014) (203)
- Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol (2009) (203)
- The autophagic network and cancer (2018) (203)
- Mitochondria, AIF and caspases — rivaling for cell death execution (2003) (202)
- Role of the Mitochondrial Permeability Transition Pore in Apoptosis (1997) (202)
- Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death (2008) (202)
- Mitochondria--the suicide organelles. (2001) (202)
- DNA topoisomerases from rat liver: physiological variations. (1983) (201)
- Mitochondrial control of apoptosis: an overview. (1999) (201)
- Life's smile, death's grin: vital functions of apoptosis-executing proteins. (2004) (199)
- Mitochondrial permeability transition in apoptosis and necrosis (2005) (197)
- Muscle-Specific Loss of Apoptosis-Inducing Factor Leads to Mitochondrial Dysfunction, Skeletal Muscle Atrophy, and Dilated Cardiomyopathy (2005) (194)
- Methods for assessing autophagy and autophagic cell death. (2008) (194)
- Autophagy for tissue homeostasis and neuroprotection. (2011) (193)
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans. (2019) (192)
- Chemotherapy and radiotherapy: cryptic anticancer vaccines. (2010) (191)
- Ecto‐calreticulin in immunogenic chemotherapy (2007) (191)
- Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells (2000) (190)
- Why yeast cells can undergo apoptosis: death in times of peace, love, and war (2006) (190)
- Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes. (1998) (189)
- Highly Ordered Spatial Organization of the Structural Long Noncoding NEAT1 RNAs within Paraspeckle Nuclear Bodies (2010) (188)
- Targeting mitochondrial apoptosis by betulinic acid in human cancers. (2009) (188)
- Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437 (2001) (187)
- Bid acts on the permeability transition pore complex to induce apoptosis (2000) (187)
- Ferroptosis (2020) (187)
- Apoptosis regulation in tetraploid cancer cells (2006) (186)
- Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis. (1996) (185)
- Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy (2011) (185)
- Caloric restriction mimetics: towards a molecular definition (2014) (185)
- Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere (2018) (185)
- Autophagy in aging, disease and death: the true identity of a cell death impostor (2009) (184)
- Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells (2009) (184)
- GD3 ganglioside directly targets mitochondria in a bcl‐2‐controlled fashion (2000) (182)
- Bcl-2 and Bax modulate adenine nucleotide translocase activity. (2003) (181)
- Potassium leakage during the apoptotic degradation phase. (1998) (181)
- Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling (2013) (181)
- Trial watch: FDA-approved Toll-like receptor agonists for cancer therapy (2012) (179)
- Resveratrol, a tumor‐suppressive compound from grapes, induces apoptosis via a novel mitochondrial pathway controlled by Bcl‐2 (2001) (179)
- AIF: Not Just an Apoptosis‐Inducing Factor (2009) (178)
- Mitochondria in chemotherapy-induced apoptosis: a prospective novel target of cancer therapy (review). (1998) (178)
- A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast (2011) (177)
- Trial watch (2013) (176)
- Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification (2014) (175)
- Mitochondrial fusion and fission in the control of apoptosis. (2005) (175)
- Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists (2013) (174)
- The crystal structure of the mouse apoptosis-inducing factor AIF (2002) (174)
- Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics (2017) (173)
- Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition (2000) (173)
- Viral proteins targeting mitochondria: controlling cell death. (2004) (172)
- Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo (1993) (172)
- Chloroquine and hydroxychloroquine for cancer therapy (2014) (169)
- Trial Watch: Monoclonal antibodies in cancer therapy (2012) (167)
- Apoptosis: Mitochondrial Membrane Permeabilization – The (W)hole Story? (2003) (167)
- The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe (2004) (167)
- Organelle-Specific Initiation of Autophagy. (2015) (164)
- Erythrocytes: Death of a mummy (2001) (164)
- Senescence, Apoptosis or Autophagy? (2008) (164)
- Rabies virus P and small P products interact directly with PML and reorganize PML nuclear bodies (2002) (163)
- Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope (2005) (163)
- Predictors of responses to immune checkpoint blockade in advanced melanoma (2017) (162)
- Hallmarks of Health (2020) (162)
- Peripheral benzodiazepine receptor ligands reverse apoptosis resistance of cancer cells in vitro and in vivo. (2002) (162)
- Association and dissociation of autophagy, apoptosis and necrosis by systematic chemical study (2011) (162)
- The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition (1998) (158)
- Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo (1995) (158)
- Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection (2011) (158)
- Programmed necrosis from molecules to health and disease. (2011) (156)
- Chaperone-mediated autophagy degrades mutant p53. (2013) (156)
- Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo. (2001) (156)
- Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties. (2016) (155)
- Autophagic removal of micronuclei (2012) (155)
- Autophagic removal of micronuclei (2012) (155)
- Genetic analysis of the mammalian cell death machinery. (2002) (155)
- Peptides and aptamers targeting HSP70: a novel approach for anticancer chemotherapy. (2011) (153)
- Mitochondrial control of the NLRP3 inflammasome (2011) (153)
- Life with or without AIF. (2010) (153)
- Mechanisms of apoptosis induction by the HIV-1 envelope (2005) (153)
- Defining the critical hurdles in cancer immunotherapy (2011) (152)
- Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers. (1995) (152)
- Mechanisms of apoptotic phosphatidylserine exposure (2013) (150)
- Mitophagy: An Emerging Role in Aging and Age-Associated Diseases (2020) (150)
- Caspases disrupt mitochondrial membrane barrier function (1998) (150)
- Phosphatidylethanolamine positively regulates autophagy and longevity (2015) (150)
- Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease. (2011) (149)
- Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma. (2006) (149)
- Intranuclear distribution of poly(A) RNA determined by electron microscope in situ hybridization. (1993) (149)
- Autophagy in acute brain injury (2016) (148)
- Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV‐1 envelope (2002) (148)
- hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway (2006) (148)
- Trial watch (2013) (148)
- Spermidine: A novel autophagy inducer and longevity elixir (2010) (147)
- Mitochondrial Membrane Permeabilization during the Apoptotic Process (1999) (147)
- Cellular degradation systems in ferroptosis (2021) (147)
- Unsaturated fatty acids induce non‐canonical autophagy (2015) (146)
- Cisplatin resistance associated with PARP hyperactivation. (2013) (146)
- Unsaturated fatty acids induce non‐canonical autophagy (2015) (146)
- Cuproptosis: a copper-triggered modality of mitochondrial cell death (2022) (146)
- Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-Induced Apoptosis Involves Mammalian Target of Rapamycin/Fkbp12-Rapamycin–Associated Protein–Mediated P53 Phosphorylation (2001) (145)
- Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity (2019) (143)
- Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C‐ring conformation (2017) (142)
- Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics (2019) (142)
- Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation (2014) (142)
- Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis. (2015) (141)
- Calreticulin Expression in Human Non-Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis. (2016) (141)
- The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus. (1999) (140)
- Targeting mitochondria for cardiovascular disorders: therapeutic potential and obstacles (2018) (140)
- PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism. (2018) (140)
- Crizotinib-induced immunogenic cell death in non-small cell lung cancer (2019) (140)
- Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. (2001) (140)
- The life span-prolonging effect of Sirtuin-1 is mediated by autophagy (2010) (140)
- Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos (2010) (140)
- Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization (2002) (138)
- Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic. (2007) (138)
- Trial Watch: Toll-like receptor agonists in cancer immunotherapy (2018) (138)
- Cross-reactivity between tumor MHC class I–restricted antigens and an enterococcal bacteriophage (2020) (138)
- Ferroptosis in infection, inflammation, and immunity (2021) (137)
- Targeting NF-κB in hematologic malignancies (2006) (136)
- p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200 (2011) (135)
- Immunogenic cell stress and death (2022) (135)
- Identification of autonomous IAP LTR retrotransposons mobile in mammalian cells (2004) (134)
- Functional Mitochondria Are Required for α-Synuclein Toxicity in Aging Yeast* (2008) (134)
- A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. (2007) (133)
- Calcium signaling and cell cycle: Progression or death. (2017) (133)
- Critical role of photoreceptor apoptosis in functional damage after retinal detachment (2002) (133)
- A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. (2007) (133)
- Illicit survival of cancer cells during polyploidization and depolyploidization (2011) (133)
- Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury (2016) (132)
- Pyroptosis – a cell death modality of its kind? (2010) (132)
- Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event (2001) (132)
- Immune response against dying tumor cells. (2004) (132)
- The effects of p53 on whole organism longevity are mediated by autophagy (2008) (131)
- Autophagy in Cardiovascular Aging. (2018) (130)
- NF-κB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome (2005) (130)
- Caspase-dependent and caspase-independent cell death pathways in yeast. (2009) (130)
- Crosstalk between ER stress and immunogenic cell death. (2013) (130)
- Guidelines and recommendations on yeast cell death nomenclature (2018) (129)
- Higher spermidine intake is linked to lower mortality: a prospective population-based study. (2018) (128)
- Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study. (2008) (127)
- Gut Bacteria Composition Drives Primary Resistance to Cancer Immunotherapy in Renal Cell Carcinoma Patients. (2020) (126)
- eIF2α phosphorylation is pathognomonic for immunogenic cell death (2018) (125)
- Life, death and burial: multifaceted impact of autophagy. (2008) (125)
- Contribution of RIP3 and MLKL to immunogenic cell death signaling in cancer chemotherapy (2016) (125)
- A yeast BH3‐only protein mediates the mitochondrial pathway of apoptosis (2011) (125)
- An Anti-apoptotic Viral Protein That Recruits Bax to Mitochondria* (2004) (125)
- Antitumor Benefits of Antiviral Immunity: An Underappreciated Aspect of Oncolytic Virotherapies. (2017) (124)
- A Role of the Mitochondrial Apoptosis-Inducing Factor in Granulysin-Induced Apoptosis1 (2001) (124)
- Viral and bacterial proteins regulating apoptosis at the mitochondrial level (2001) (124)
- BH3 mimetics activate multiple pro-autophagic pathways (2011) (124)
- Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade (2019) (124)
- Trial watch (2012) (124)
- Immunological Mechanisms Underneath the Efficacy of Cancer Therapy (2016) (123)
- Plasma membrane potential in thymocyte apoptosis. (1999) (123)
- Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia (2010) (123)
- Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology (2020) (123)
- Spermidine protects against α-synuclein neurotoxicity (2014) (122)
- Immunological off-target effects of imatinib (2016) (120)
- Hormesis, cell death and aging (2011) (119)
- Clinical impact of the NKp30/B7-H6 axis in high-risk neuroblastoma patients (2015) (118)
- Hallmarks of T cell aging (2021) (118)
- Cell Cycle-Dependent Induction of Autophagy, Mitophagy and Reticulophagy (2007) (118)
- Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin (2008) (117)
- RIP kinases initiate programmed necrosis. (2009) (117)
- The adenine nucleotide translocator in apoptosis. (2002) (117)
- Nonapoptotic role for Apaf-1 in the DNA damage checkpoint. (2007) (115)
- NF-κB and p53 Are the Dominant Apoptosis-inducing Transcription Factors Elicited by the HIV-1 Envelope (2004) (115)
- Targeting post-mitochondrial effectors of apoptosis for neuroprotection. (2009) (114)
- Prognostic impact of vitamin B6 metabolism in lung cancer. (2012) (114)
- Localization of cyclin A at the sites of cellular DNA replication. (1993) (114)
- The Warburg Effect Suppresses Oxidative Stress Induced Apoptosis in a Yeast Model for Cancer (2009) (114)
- CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. (2014) (113)
- Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway byCaspase-9 (2006) (113)
- Dynamic changes in Mcl-1 expression regulate macrophage viability or commitment to apoptosis during bacterial clearance. (2005) (113)
- Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer (2015) (113)
- Comprehensive analysis of current approaches to inhibit regulatory T cells in cancer (2012) (112)
- HIV induces lymphocyte apoptosis by a p53‐initiated, mitochondrial‐mediated mechanism (2001) (111)
- The immunogenicity of tumor cell death (2009) (111)
- Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications (2015) (111)
- Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma. (2017) (110)
- Trial watch (2012) (110)
- Targeting p53 to mitochondria for cancer therapy (2008) (110)
- Immunogenicity of anthracyclines: moving towards more personalized medicine. (2008) (109)
- Tumor-Infiltrating Regulatory T Cells: Phenotype, Role, Mechanism of Expansion In Situ and Clinical Significance (2013) (109)
- Calreticulin exposure on malignant blasts predicts a cellular anticancer immune response in patients with acute myeloid leukemia (2010) (108)
- Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone. (2008) (108)
- Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach. (2007) (108)
- Methanobactin reverses acute liver failure in a rat model of Wilson disease. (2016) (107)
- BH3‐only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α (2012) (107)
- The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma (2014) (107)
- Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis. (2019) (107)
- Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands. (2010) (107)
- Trial watch: Peptide-based vaccines in anticancer therapy (2018) (106)
- Non‐apoptotic functions of apoptosis‐regulatory proteins (2012) (106)
- A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity. (2004) (105)
- Enlightening the impact of immunogenic cell death in photodynamic cancer therapy (2012) (105)
- Harnessing γδ T cells in anticancer immunotherapy. (2012) (104)
- p53 represses autophagy in a cell cycle-dependent fashion (2008) (104)
- Implication of mitochondria in apoptosis (1997) (104)
- Apoptosis-inducing factor determines the chemoresistance of non-small-cell lung carcinomas (2004) (104)
- Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set (2014) (104)
- PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development (2016) (103)
- Trial Watch: Immunostimulation with Toll-like receptor agonists in cancer therapy (2016) (103)
- Disruption of the hexokinase–VDAC complex for tumor therapy (2008) (102)
- Trial Watch: Peptide-based anticancer vaccines (2015) (102)
- Effects of vitamin B6 metabolism on oncogenesis, tumor progression and therapeutic responses (2013) (101)
- Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. (2012) (101)
- Trial Watch (2013) (101)
- Regulated cell death and adaptive stress responses (2016) (100)
- Lithium-Mediated Long-Term Neuroprotection in Neonatal Rat Hypoxia–Ischemia is Associated with Antiinflammatory Effects and Enhanced Proliferation and Survival of Neural Stem/Progenitor Cells (2011) (100)
- Erratum: Molecular mechanisms of cell death: Central implication of ATP synthase in mitochondrial permeability transition (Oncogene (2015) 34 (1475-1486 ) DOI: 10.1038/onc.2014.96) (2015) (100)
- Immunogenic cell death in radiation therapy (2013) (100)
- Surface‐exposed calreticulin in the interaction between dying cells and phagocytes (2010) (100)
- Autophagy is required for the activation of NFκB (2012) (99)
- Inhibition of autophagy by TAB2 and TAB3 (2011) (99)
- Inhibition of autophagy by TAB2 and TAB3 (2011) (99)
- Predictive biomarkers for cancer therapy with PARP inhibitors (2014) (99)
- Trial watch: STING agonists in cancer therapy (2020) (98)
- Cancer immunotherapy in 2017: The breakthrough of the microbiota (2018) (97)
- Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25 (2015) (97)
- The mitochondrion as an integrator/coordinator of cell death pathways (1998) (97)
- Cyclosporin A prevents calpain activation despite increased intracellular calcium concentrations, as well as translocation of apoptosis‐inducing factor, cytochrome c and caspase‐3 activation in neurons exposed to transient hypoglycemia (2003) (96)
- Caspase-independent commitment phase to apoptosis in activated blood T lymphocytes: reversibility at low apoptotic insult. (2000) (96)
- Enhancement of radiation response in p53-deficient cancer cells by the Aurora-B kinase inhibitor AZD1152 (2007) (96)
- Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jurkat cells: correlation with changes in mitochondria, glutathione depletion, intracellular acidification and caspase 3 activation. (2001) (96)
- Optimising efficacy and reducing toxicity of anticancer radioimmunotherapy. (2019) (96)
- Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA (2006) (96)
- A dual role of p 53 in the control of autophagy (96)
- Redundant cell death mechanisms as relics and backups (2005) (96)
- Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis (2014) (95)
- Adenine nucleotide translocase: a component of the phylogenetically conserved cell death machinery (2009) (95)
- Chemosensitization by knockdown of adenine nucleotide translocase-2. (2006) (95)
- Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients. (2016) (95)
- Regulation of cytoplasmic stress granules by apoptosis-inducing factor (2004) (95)
- An infectious progenitor for the murine IAP retrotransposon: emergence of an intracellular genetic parasite from an ancient retrovirus. (2008) (95)
- Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis. (1998) (94)
- Autophagy-dependent ATP release from dying cells via lysosomal exocytosis (2013) (94)
- Hallmarks of aging: An expanding universe (2022) (94)
- Autophagy for the avoidance of neurodegeneration. (2009) (94)
- Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator (2012) (93)
- Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism (2018) (93)
- The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer (2016) (92)
- Mitochondrial release of apoptosis-inducing factor and cytochrome c during smooth muscle cell apoptosis. (2001) (92)
- Cell death in pancreatic cancer: from pathogenesis to therapy (2021) (92)
- The role of interleukin 2 in autoimmunity. (1989) (91)
- Characterization of novel MPS1 inhibitors with preclinical anticancer activity (2013) (91)
- Autophagy in hepatic adaptation to stress. (2020) (91)
- Trial watch: Dendritic cell-based anticancer immunotherapy (2017) (91)
- Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer (2022) (91)
- Trial watch: dendritic cell vaccination for cancer immunotherapy (2019) (90)
- Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-XL (2002) (90)
- Arsenic trioxide, a novel mitochondriotoxic anticancer agent? (1999) (90)
- Thymosin α1 represents a potential potent single molecule-based therapy for cystic fibrosis (2017) (90)
- Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis (2004) (90)
- The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes. (1998) (90)
- The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family (2003) (89)
- The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway (2002) (89)
- Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death (2012) (89)
- Mechanisms of mitochondrial membrane permeabilization (2000) (89)
- Mitochondrial Proteins Containing Coiled-Coil-Helix-Coiled-Coil-Helix (CHCH) Domains in Health and Disease. (2016) (89)
- Oncosuppressive functions of autophagy. (2011) (89)
- Mitochondria in cancer (2006) (89)
- Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor. (2005) (89)
- TMEM173 Drives Lethal Coagulation in Sepsis. (2020) (88)
- PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor (2005) (88)
- Mitochondrial apoptosis without VDAC (2007) (88)
- Tumor stress, cell death and the ensuing immune response (2008) (87)
- Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer (2020) (87)
- Immunomodulation by targeted anticancer agents. (2020) (87)
- Apoptosis induction by the photosensitizer verteporfin: identification of mitochondrial adenine nucleotide translocator as a critical target. (2001) (87)
- Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3. (2003) (87)
- Spermidine promotes stress resistance in Drosophila melanogaster through autophagy-dependent and -independent pathways (2012) (87)
- Metabolic targets for cancer therapy (2013) (87)
- Apoptosis: Condensed matter in cell death (1999) (87)
- Prerequisites for the antitumor vaccine-like effect of chemotherapy and radiotherapy. (2011) (87)
- Oxidative phosphorylation as a potential therapeutic target for cancer therapy (2019) (86)
- Trial Watch (2012) (86)
- Immune Checkpoint Blockade, Immunogenic Chemotherapy or IFN-α Blockade Boost the Local and Abscopal Effects of Oncolytic Virotherapy. (2017) (86)
- The Molecular Hallmarks of the Serrated Pathway in Colorectal Cancer (2019) (86)
- Pro-autophagic polyphenols reduce the acetylation of cytoplasmic proteins (2012) (86)
- The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1 (2009) (86)
- TP53 and MTOR crosstalk to regulate cellular senescence (2010) (85)
- eIF2α phosphorylation as a biomarker of immunogenic cell death. (2015) (85)
- Aspirin Recapitulates Features of Caloric Restriction (2018) (85)
- Megakaryocyte polyploidization is associated with a functional gene amplification. (2003) (85)
- Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1 (2010) (84)
- Functions of BCL-XL at the Interface between Cell Death and Metabolism (2013) (84)
- Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment (2002) (84)
- The Obese Strain of Chickens: An Animal Model with Spontaneous Autoimmune Thyroiditis (1989) (83)
- Trial Watch (2013) (83)
- Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma (2004) (83)
- The immuno-oncological challenge of COVID-19 (2020) (83)
- Combined evaluation of LC3B puncta and HMGB1 expression predicts residual risk of relapse after adjuvant chemotherapy in breast cancer (2015) (83)
- Cytokines and autoimmune disease. (1991) (82)
- A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR (2016) (82)
- A cytofluorometric assay of nuclear apoptosis induced in a cell-free system: application to ceramide-induced apoptosis. (1997) (82)
- Mitochondrial Control of Cell Death Induced by HIV‐1‐Encoded Proteins (2000) (82)
- Calreticulin and cancer (2020) (82)
- Lysosomes and mitochondria in the commitment to apoptosis: a potential role for cathepsin D and AIF (2004) (82)
- Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? (2018) (82)
- Fine-Tuning Cancer Immunotherapy: Optimizing the Gut Microbiome. (2016) (82)
- The intimate relationship between gut microbiota and cancer immunotherapy (2018) (82)
- NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome. (2006) (82)
- Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade (2020) (82)
- The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs. (2017) (81)
- Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25 (2015) (81)
- The pharmacology of T cell apoptosis. (1995) (81)
- Immune responses during COVID-19 infection (2020) (81)
- MaBoSS 2.0: an environment for stochastic Boolean modeling (2017) (80)
- Immunogenic calreticulin exposure occurs through a phylogenetically conserved stress pathway involving the chemokine CXCL8 (2013) (80)
- How to improve the immunogenicity of chemotherapy and radiotherapy (2011) (80)
- Pre-processed caspase-9 contained in mitochondria participates in apoptosis (2002) (80)
- The dendritic cell-tumor cross-talk in cancer. (2011) (80)
- Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers (2014) (80)
- Molecular and cellular mechanisms of T lymphocyte apoptosis. (1998) (80)
- A Cardinal Role for Cathepsin D in Co-Ordinating the Host-Mediated Apoptosis of Macrophages and Killing of Pneumococci (2011) (79)
- Mitochondrial control of cell death induced by hyperosmotic stress (2006) (79)
- Critical Involvement of the ATM-Dependent DNA Damage Response in the Apoptotic Demise of HIV-1-Elicited Syncytia (2008) (79)
- Inhibition of Chk1 Kills Tetraploid Tumor Cells through a p53-Dependent Pathway (2007) (79)
- Molecular mechanisms of selective autophagy (2012) (79)
- Simplification of complex peptide mixtures for proteomic analysis: Reversible biotinylation of cysteinyl peptides (2000) (79)
- Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease (2013) (79)
- Interleukin-2, autotolerance, and autoimmunity. (1991) (79)
- Trial Watch (2012) (79)
- Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice (1991) (79)
- Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events. (2003) (78)
- Mitochondrial regulation of cell death: a phylogenetically conserved control (2016) (78)
- Caspase activation is not death (2003) (78)
- Contribution of IL-17–producing γδ T cells to the efficacy of anticancer chemotherapy (2011) (78)
- Targeting NF-kappaB in hematologic malignancies. (2006) (78)
- Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance (2014) (77)
- ATP-dependent recruitment, survival and differentiation of dendritic cell precursors in the tumor bed after anticancer chemotherapy (2013) (77)
- Extracellular nucleosides and nucleotides as immunomodulators (2017) (77)
- Chemosensitization by a non-apoptogenic heat shock protein 70-binding apoptosis-inducing factor mutant. (2003) (77)
- Ferritinophagy and ferroptosis in the management of metabolic diseases (2021) (77)
- The Inositol Trisphosphate Receptor in the Control of Autophagy (2007) (77)
- BAX and BAK1 are dispensable for ABT-737-induced dissociation of the BCL2-BECN1 complex and autophagy (2015) (77)
- NUPR1 is a critical repressor of ferroptosis (2021) (77)
- Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers (2021) (76)
- Oxaliplatin-induced mitochondrial apoptotic response of colon carcinoma cells does not require nuclear DNA (2004) (76)
- Fatal liaisons of p53 with Bax and Bak (2004) (76)
- Trial watch (2013) (76)
- Metacaspases are caspases. Doubt no more (2010) (75)
- The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species (2019) (75)
- Pharmacological inhibition of programmed lymphocyte death. (1994) (75)
- Effects of interleukin-2 in immunostimulation and immunosuppression (2019) (75)
- Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition (2015) (75)
- Nervous yeast: modeling neurotoxic cell death. (2010) (75)
- Heating it up: Oncolytic viruses make tumors ‘hot’ and suitable for checkpoint blockade immunotherapies (2018) (74)
- Palmitate induces apoptosis via a direct effect on mitochondria (1999) (74)
- Selective Resistance of Tetraploid Cancer Cells against DNA Damage‐Induced Apoptosis (2006) (74)
- ATM mediates constitutive NF-κB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia (2009) (74)
- JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice. (2017) (73)
- Rat liver HMG1: a physiological nucleosome assembly factor. (1984) (73)
- Trial Watch (2014) (72)
- The oncolytic peptide LTX-315 triggers immunogenic cell death (2016) (72)
- The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor? (2019) (72)
- Immune-related gene signatures predict the outcome of neoadjuvant chemotherapy (2014) (72)
- Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference (2007) (72)
- Immunohistochemical detection of cytoplasmic LC3 puncta in human cancer specimens (2012) (72)
- STAT3 Inhibition Enhances the Therapeutic Efficacy of Immunogenic Chemotherapy by Stimulating Type 1 Interferon Production by Cancer Cells. (2015) (71)
- Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects. (2009) (71)
- Desirable cell death during anticancer chemotherapy (2010) (71)
- Pro-necrotic molecules impact local immunosurveillance in human breast cancer (2017) (71)
- Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential. (1996) (71)
- Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death. (2011) (71)
- The association of prosomes with some of the intermediate filament networks of the animal cell [published erratum appears in J Cell Biol 1989 Mar;108(3):following 1175] (1988) (70)
- Linomide, a novel immunomodulator that prevents death in four models of septic shock (1993) (70)
- Measurement of membrane permeability and the permeability transition of mitochondria. (2007) (70)
- Trial watch: Dendritic cell-based anticancer therapy (2014) (70)
- Expansion and clonal deletion of peripheral T cells induced by bacterial superantigen is independent of the interleukin‐2 pathway (1992) (70)
- Harnessing dendritic cells in cancer. (2011) (70)
- An autophagy-dependent anticancer immune response determines the efficacy of melanoma chemotherapy (2014) (69)
- Nicotinamide for the treatment of heart failure with preserved ejection fraction (2021) (69)
- cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis (2019) (68)
- ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis (2013) (68)
- Microbiota tryptophan metabolism induces aryl hydrocarbon receptor activation and improves alcohol-induced liver injury (2020) (68)
- Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials (2016) (67)
- Colorectal cancer: the first neoplasia found to be under immunosurveillance and the last one to respond to immunotherapy? (2015) (67)
- Viral subversion of immunogenic cell death (2009) (67)
- Autophagy couteracts weight gain, lipotoxicity and pancreatic β-cell death upon hypercaloric pro-diabetic regimens (2017) (67)
- Links between innate and cognate tumor immunity. (2007) (67)
- Metabolic vulnerability of cisplatin‐resistant cancers (2018) (67)
- TumGrowth: An open-access web tool for the statistical analysis of tumor growth curves (2018) (66)
- Metabolic effects of fasting on human and mouse blood in vivo (2017) (66)
- Carbotoxicity—Noxious Effects of Carbohydrates (2018) (66)
- Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance (2017) (66)
- Caspase-3 and prostaglandins signal for tumor regrowth in cancer therapy (2012) (66)
- Mitochondria as therapeutic targets for the treatment of malignant disease. (2011) (66)
- The propeptide of yeast cathepsin D inhibits programmed necrosis (2011) (65)
- Oncolysis without viruses — inducing systemic anticancer immune responses with local therapies (2019) (65)
- Possible contribution of apoptosis‐inducing factor (AIF) and reactive oxygen species (ROS) to UVB‐induced caspase‐independent cell death in the T cell line Jurkat (2003) (65)
- Chlorpromazine amplifies macrophage-dependent IL-10 production in vivo. (1995) (65)
- Human CD4 and human major histocompatibility complex class II (DQ6) transgenic mice: supersensitivity to superantigen‐induced septic shock (1996) (65)
- Immunoregulation by cytokines. (1993) (64)
- Differential involvement of Th1 and Th2 cytokines in autoimmune diseases. (1996) (64)
- Organization of a functional chicken class II B gene (2004) (64)
- Immunosuppression by Mutated Calreticulin Released from Malignant Cells. (2019) (64)
- Akt‐mediated phosphorylation of MICU1 regulates mitochondrial Ca2+ levels and tumor growth (2018) (64)
- PDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis. (2021) (64)
- Immunogenic cell death inducers as anticancer agents (2014) (64)
- Measurement of membrane permeability and permeability transition of mitochondria. (2001) (64)
- Organs on chip approach: a tool to evaluate cancer -immune cells interactions (2017) (64)
- Cytolocalization of prosomes as a function of differentiation. (1988) (63)
- Overcoming chemoresistance of non-small cell lung carcinoma through restoration of an AIF-dependent apoptotic pathway (2008) (63)
- Quantitation of mitochondrial transmembrane potential in cells and in isolated mitochondria. (2000) (63)
- Digesting the crisis: autophagy and coronaviruses (2020) (63)
- MLKL regulates necrotic plasma membrane permeabilization (2014) (63)
- Radiosensitization by Chir-124, a selective Chk1 inhibitor: Effects of p53 and cell cycle checkpoints (2009) (63)
- Chemosensitization by erythropoietin through inhibition of the NF-κB rescue pathway (2005) (63)
- Resveratrol and aspirin eliminate tetraploid cells for anticancer chemoprevention (2014) (62)
- Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo (2002) (62)
- HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice. (2008) (62)
- Cysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation (2017) (62)
- Physical interaction of apoptosis-inducing factor with DNA and RNA (2006) (61)
- Photodynamic therapy with redaporfin targets the endoplasmic reticulum and Golgi apparatus (2018) (61)
- Targeting autophagy in ischemic stroke: From molecular mechanisms to clinical therapeutics. (2021) (61)
- Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer (2014) (61)
- Mitochondrion-targeted apoptosis regulators of viral origin. (2003) (61)
- Viral strategies for the evasion of immunogenic cell death (2010) (60)
- Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome (2009) (60)
- Trial Watch: Immunotherapy plus radiation therapy for oncological indications (2016) (60)
- Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. (2019) (60)
- Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia (2012) (60)
- Dietary spermidine improves cognitive function. (2021) (60)
- Targeting the gut and tumor microbiota in cancer (2022) (60)
- Trial watch: Immune checkpoint blockers for cancer therapy (2017) (59)
- Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors (2018) (59)
- Homotypic cell cannibalism, a cell-death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer (2012) (59)
- Immunogenic and Non-immunogenic Cell Death in the Tumor Microenvironment. (2017) (58)
- DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4+ T Cells Infected with HIV (2013) (58)
- Subversion of the chemotherapy-induced anticancer immune response by the ecto-ATPase CD39 (2012) (57)
- Mitochondrion-mediated apoptosis in HIV-1 infection. (2003) (57)
- Purification of mitochondria for apoptosis assays. (2000) (57)
- The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca2+ levels to α-synuclein toxicity in Parkinson's disease models (2012) (57)
- Glycogen synthase kinase 3‐mediated voltage‐dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation (2013) (56)
- Noncanonical Cell Fate Regulation by Bcl-2 Proteins. (2020) (56)
- ATP and cancer immunosurveillance (2021) (56)
- Trial watch (2012) (56)
- Synergistic interaction between cisplatin and PARP inhibitors in non-small cell lung cancer (2013) (56)
- Differential in vivo effects of a superantigen and an antibody targeted to the same T cell receptor. Activation-induced cell death vs passive macrophage-dependent deletion. (1994) (56)
- Dietary spermidine for lowering high blood pressure (2017) (56)
- ERCC1-specific immunostaining in non-small-cell lung cancer. (2007) (55)
- Combinatorial Strategies for the Induction of Immunogenic Cell Death (2015) (55)
- Chemokine receptor patterns in lymphocytes mirror metastatic spreading in melanoma. (2016) (55)
- Neuroendocrine regulation of autophagy by leptin (2011) (55)
- Neuroendocrine regulation of autophagy by leptin (2011) (55)
- Trial Watch: Adoptively transferred cells for anticancer immunotherapy (2017) (55)
- NF-κB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia (2007) (55)
- Control of apoptotic DNA degradation (2000) (54)
- The negative impact of antibiotics on outcomes in cancer patients treated with immunotherapy: a new independent prognostic factor? (2019) (54)
- Molecular Genetics of the Chicken MHC: Current Status and Evolutionary Aspects (1990) (54)
- Mitochondria as Targets of Apoptosis Regulation by Nitric Oxide (2003) (54)
- Fatty acids trigger mitochondrion-dependent necrosis (2010) (53)
- Synergistic proapoptotic effects of the two tyrosine kinase inhibitors pazopanib and lapatinib on multiple carcinoma cell lines (2009) (53)
- Spermidine delays aging in humans (2018) (53)
- Targeting HSP70 for cancer therapy. (2009) (53)
- Immunosurveillance as a regulator of tissue homeostasis. (2013) (53)
- A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies. (2013) (53)
- Organelle-specific regulation of ferroptosis (2021) (53)
- Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy (2013) (53)
- Ammonia: A Diffusible Factor Released by Proliferating Cells That Induces Autophagy (2010) (52)
- Concurrent induction of necrosis, apoptosis, and autophagy in ischemic preconditioned human livers formerly treated by chemotherapy. (2009) (52)
- Physiology and pathology of an immunoendocrine feedback loop. (1988) (52)
- Quiescence Preconditioned Human Multipotent Stromal Cells Adopt a Metabolic Profile Favorable for Enhanced Survival under Ischemia (2017) (52)
- The Tumor Suppressor p 53 Limits Ferroptosis by Blocking DPP 4 Activity (2018) (52)
- Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells (2012) (52)
- Oral administration of Akkermansia muciniphila elevates systemic antiaging and anticancer metabolites (2021) (52)
- Cell Death Signaling and Anticancer Therapy (2011) (52)
- Compartmentalization of the peripheral immune system. (1993) (51)
- Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer (2020) (51)
- Mitochondrial Apoptosis and the Peripheral Benzodiazepine Receptor (2002) (51)
- A novel effect of DNA methyltransferase and histone deacetylase inhibitors : NFκB inhibition in malignant myeloblasts (2008) (51)
- Trial Watch (2012) (51)
- Past, Present, and Future of Molecular and Cellular Oncology (2011) (51)
- Erlotinib antagonizes ABC transporters in acute myeloid leukemia (2012) (51)
- The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1 (2018) (51)
- Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia (2007) (51)
- Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition. (2008) (50)
- Trial Watch: Radioimmunotherapy for oncological indications (2014) (50)
- Introduction: mitochondrial control of apoptosis. (2002) (50)
- The ratio of CD8+/FOXP3 T lymphocytes infiltrating breast tissues predicts the relapse of ductal carcinoma in situ (2016) (50)
- The Aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe (2009) (50)
- Autophagy in non-small cell lung carcinogenesis (2014) (50)
- The obese strain of chickens: an animal model with spontaneous autoimmune thyroiditis. (1974) (50)
- MCL-1 dependency of cisplatin-resistant cancer cells. (2014) (50)
- Inactivation of retinoblastoma family proteins by SV40 T antigen results in creation of a hepatocyte growth factor/scatter factor autocrine loop associated with an epithelial-fibroblastoid conversion and invasiveness. (1997) (50)
- NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia. (2007) (50)
- Anticancer activity of cardiac glycosides (2012) (50)
- Negative prognostic impact of regulatory T cell infiltration in surgically resected esophageal cancer post-radiochemotherapy (2015) (50)
- Disease-relevant proteostasis regulation of cystic fibrosis transmembrane conductance regulator (2013) (49)
- Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin (2015) (49)
- Trial Watch: Lenalidomide-based immunochemotherapy (2013) (49)
- Autophagy in natural and therapy-driven anticancer immunosurveillance (2017) (49)
- The transferrin receptor and the tetraspanin web molecules CD9, CD81, and CD9P‐1 are differentially sorted into exosomes after TPA treatment of K562 cells (2007) (49)
- Signal Transduction Pathways Involved in B‐Cell Induction (1993) (49)
- The oncolytic peptide LTX-315 overcomes resistance of cancers to immunotherapy with CTLA4 checkpoint blockade (2016) (49)
- Apoptosis and apoptosis‐associated perturbations of peripheral blood lymphocytes during HIV infection: comparison between AIDS patients and asymptomatic long‐term non‐progressors (2000) (49)
- Trial Watch—Small molecules targeting the immunological tumor microenvironment for cancer therapy (2016) (49)
- Selective killing of p53-deficient cancer cells by SP600125 (2012) (48)
- A synergistic triad of chemotherapy, immune checkpoint inhibitors, and caloric restriction mimetics eradicates tumors in mice (2019) (48)
- Trial watch: TLR3 agonists in cancer therapy (2020) (48)
- Selective killing of p53-deficient cancer cells by SP600125 (2012) (48)
- Mechanisms of self tolerance. (1992) (48)
- Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress (2020) (48)
- Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex (2000) (48)
- CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer (2020) (47)
- Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response (2020) (47)
- Autophagy Mediates Tumor Suppression via Cellular Senescence. (2016) (47)
- The molecular archaeology of a mitochondrial death effector: AIF in Drosophila (2008) (47)
- Structure–function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA (2007) (47)
- Therapeutic modulation of autophagy: which disease comes first? (2019) (47)
- Pathophysiology of mitochondrial cell death control (1999) (47)
- Mitochondrial Apoptosis Induced by the HIV‐1 Envelope (2003) (47)
- Beneficial autoimmunity improves cancer prognosis (2021) (47)
- Murine Endogenous Retrovirus MuERV-L Is the Progenitor of the “Orphan” Epsilon Viruslike Particles of the Early Mouse Embryo (2007) (47)
- IKK connects autophagy to major stress pathways (2010) (46)
- Linomide inhibits programmed cell death of peripheral T cells in vivo (1994) (46)
- Autophagy induction for the treatment of cancer (2016) (46)
- The mTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-Activated Glioblastomas (2013) (46)
- IKK connects autophagy to major stress pathways (2010) (46)
- AIF-regulated oxidative phosphorylation supports lung cancer development (2019) (46)
- Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity (2020) (46)
- Methods to measure membrane potential and permeability transition in the mitochondria during apoptosis. (2004) (46)
- Mitochondrial permeability transition in apoptosis and necrosis (1998) (45)
- Strategies for the etiological therapy of cystic fibrosis (2017) (45)
- Coffee induces autophagy in vivo (2014) (45)
- Dimethyl α-ketoglutarate inhibits maladaptive autophagy in pressure overload-induced cardiomyopathy (2014) (45)
- Trial watch (2005) (45)
- Azacytidine and erlotinib exert synergistic effects against acute myeloid leukemia (2013) (45)
- Proteasome activation as a critical event of thymocyte apoptosis (2000) (45)
- A multiplicity of cell death pathways (2007) (45)
- Victories and deceptions in tumor immunology (2013) (44)
- A pathogenic role for cystic fibrosis transmembrane conductance regulator in celiac disease (2018) (44)
- Beclin 1: a BH3-only protein that fails to induce apoptosis (2009) (44)
- Calreticulin expression: Interaction with the immune infiltrate and impact on survival in patients with ovarian and non-small cell lung cancer (2016) (44)
- Essential role for oxidative phosphorylation in cancer progression. (2015) (44)
- Bax inhibitor‐1 protects from nonalcoholic steatohepatitis by limiting inositol‐requiring enzyme 1 alpha signaling in mice (2018) (44)
- Impact of Pattern Recognition Receptors on the Prognosis of Breast Cancer Patients Undergoing Adjuvant Chemotherapy. (2016) (44)
- Trial watch: Tumor-targeting monoclonal antibodies for oncological indications (2015) (44)
- Trial Watch—Immunostimulation with cytokines in cancer therapy (2016) (44)
- Clinical evidence that immunogenic cell death sensitizes to PD-1/PD-L1 blockade (2019) (44)
- Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5 (2009) (43)
- Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients (2019) (43)
- Genetic LAMP2 deficiency accelerates the age-associated formation of basal laminar deposits in the retina (2019) (43)
- Complete variable region sequence of a nonfunctionally rearranged kappa light chain transcribed in the nonsecretor P3-X63-Ag8.653 myeloma cell line. (1987) (43)
- Molecular mechanisms of sulfasalazine‐induced T‐cell apoptosis (2002) (43)
- The mitochondrial permeability transition pore complex as a pharmacological target. An introduction. (2003) (43)
- Signal Peptide Peptidase-catalyzed Cleavage of Hepatitis C Virus Core Protein Is Dispensable for Virus Budding but Destabilizes the Viral Capsid* (2006) (42)
- Autophagy in stress and disease (2015) (42)
- Mitochondria in cancer (2006) (42)
- The metabolomic signature of extreme longevity: naked mole rats versus mice (2019) (42)
- Entosis, a key player in cancer cell competition (2014) (42)
- Mitochondria in cancer (2006) (42)
- Loss-of-function alleles of P2RX7 and TLR4 fail to affect the response to chemotherapy in non-small cell lung cancer (2012) (42)
- Impaired autophagosome-lysosome fusion in the pathogenesis of pancreatitis (2009) (42)
- Mutant MyoD Lacking Cdc2 Phosphorylation Sites Delays M-Phase Entry (2004) (42)
- Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization (2003) (42)
- Defective autophagy control by the p53 rheostat in cancer (2010) (42)
- p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis (2009) (42)
- Immunogenic cell death-related biomarkers: Impact on the survival of breast cancer patients after adjuvant chemotherapy (2016) (41)
- 4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG (2008) (41)
- A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB1 transcription (2015) (41)
- Immunotherapy and the concept of a clinical cure. (2013) (41)
- Trial Watch (2014) (41)
- EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cells (2013) (41)
- Apoptosis-inducing factor deficiency decreases the proliferation rate and protects the subventricular zone against ionizing radiation (2010) (40)
- The immune response against dying tumor cells: avoid disaster, achieve cure (2008) (40)
- The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate (2016) (40)
- 3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB (2019) (40)
- The oncolytic peptide LTX-315 kills cancer cells through Bax/Bak-regulated mitochondrial membrane permeabilization (2015) (40)
- Impact papers on aging in 2009 (2010) (40)
- Mitochondrion-dependent caspase activation by the HIV-1 envelope. (2003) (40)
- An automated fluorescence videomicroscopy assay for the detection of mitotic catastrophe (2010) (40)
- eIF2α phosphorylation: A hallmark of immunogenic cell death (2018) (40)
- Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia (2011) (40)
- Meta-analysis of organ-specific differences in the structure of the immune infiltrate in major malignancies (2015) (39)
- Pharmacological suppression of B7-H4 glycosylation restores antitumor immunity in immune-cold breast cancers. (2020) (39)
- Trial Watch: experimental TLR7/TLR8 agonists for oncological indications (2020) (39)
- Disruption of the PP1/GADD34 complex induces calreticulin exposure (2009) (39)
- Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy (2020) (39)
- Gold Standard Assessment of Immunogenic Cell Death in Oncological Mouse Models. (2018) (39)
- Mitochondrial membrane permeabilization by HIV-1 Vpr. (2004) (39)
- Ferroptosis in p53-dependent oncosuppression and organismal homeostasis (2015) (38)
- Intestinal microbiota influences clinical outcome and side effects of early breast cancer treatment (2021) (38)
- ERCC1 function in nuclear excision and interstrand crosslink repair pathways is mediated exclusively by the ERCC1-202 isoform (2013) (38)
- A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected hepatotoxicity in patients with solid tumors (2011) (38)
- Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells. (2007) (37)
- Trial Watch (2012) (37)
- Trial Watch (2014) (37)
- Autophagy for the avoidance of degenerative, inflammatory, infectious, and neoplastic disease. (2010) (37)
- Targeting ferroptosis in pancreatic cancer: a double-edged sword. (2021) (37)
- Bim and Bmf Synergize To Induce Apoptosis in Neisseria Gonorrhoeae Infection (2009) (37)
- Impact of myeloid cells on the efficacy of anticancer chemotherapy. (2014) (37)
- Tyrosine kinase inhibitors for the treatment of acute myeloid leukemia: delineation of anti-leukemic mechanisms of action. (2011) (36)
- Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations (2016) (36)
- p53 in apoptosis control: an introduction. (2005) (36)
- Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy (2018) (36)
- A Natural Polyphenol Exerts Antitumor Activity and Circumvents Anti–PD-1 Resistance through Effects on the Gut Microbiota (2022) (36)
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans. (2020) (36)
- The exonuclease ISG20 mainly localizes in the nucleolus and the Cajal (Coiled) bodies and is associated with nuclear SMN protein‐containing complexes (2006) (36)
- Antiapoptotic activity of argon and xenon (2013) (36)
- Absence of nucleosomes in a histone-containing nucleoprotein complex obtained by dissociation of purified SV40 virions (1982) (35)
- Interaction between the HIV‐1 Protein Vpr and the Adenine Nucleotide Translocator (2006) (35)
- Immunosurveillance against tetraploidization-induced colon tumorigenesis (2013) (35)
- Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells (2008) (35)
- Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia (2011) (35)
- Preferential killing of p53-deficient cancer cells by reversine (2012) (35)
- Ceramide triggers metacaspase-independent mitochondrial cell death in yeast (2011) (35)
- Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy (2014) (35)
- Longevity-relevant regulation of autophagy at the level of the acetylproteome (2011) (35)
- Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia (2011) (35)
- Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison. (2008) (35)
- Analysis of the immune‐encodrine feedback loop in the avian system and its alteration in chickens with spontaneous autoimmune thyroiditis (1990) (35)
- Murine MusD Retrotransposon: Structure and Molecular Evolution of an “Intracellularized” Retrovirus (2006) (35)
- Preferential killing of p53-deficient cancer cells by reversine (2012) (35)
- Lurbinectedin synergizes with immune checkpoint blockade to generate anticancer immunity (2019) (35)
- Radiosensitization by a novel Bcl-2 and Bcl-XL inhibitor S44563 in small-cell lung cancer (2014) (35)
- A fluorescence-microscopic and cytofluorometric system for monitoring the turnover of the autophagic substrate p62/SQSTM1 (2011) (34)
- A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2 (2010) (34)
- LIVER CIRCADIAN CLOCK, A PHARMACOLOGIC TARGET OF CYCLIN-DEPENDENT KINASE INHIBITOR SELICICLIB (2009) (34)
- The Human Stress-Activated Protein kin17 Belongs to the Multiprotein DNA Replication Complex and Associates In Vivo with Mammalian Replication Origins (2005) (34)
- Phosphoproteomic analysis of cells treated with longevity-related autophagy inducers (2012) (34)
- A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2 (2010) (34)
- The Matrix Protein of Vesicular Stomatitis Virus Binds Dynamin for Efficient Viral Assembly (2010) (34)
- On-target versus off-target effects of drugs inhibiting the replication of SARS-CoV-2 (2020) (34)
- Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells. (2007) (34)
- Mechanisms of p53-mediated mitochondrial membrane permeabilization (2008) (34)
- Multiple ways to cellular immune tolerance. (1993) (34)
- Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosis (2016) (34)
- Novel immune checkpoint blocker approved for the treatment of advanced melanoma (2014) (34)
- Characterization of cell death pathways in human immunodeficiency virus-associated encephalitis. (2005) (34)
- Intricate links between ER stress and apoptosis. (2009) (34)
- BH3 mimetics reveal the network properties of autophagy-regulatory signaling cascades (2011) (34)
- The mitochondriotoxic domain of Vpr determines HIV-1 virulence. (2003) (34)
- Depletion of Endonuclease G Selectively Kills Polyploid Cells (2007) (34)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Pertussis toxin interferes with superantigen-induced deletion of peripheral T cells without affecting T cell activation in vivo. Inhibition of deletion and associated programmed cell death depends on ADP-ribosyltransferase activity. (1994) (33)
- Subversion of anticancer immunosurveillance by radiotherapy (2015) (33)
- Acetyl-coenzyme A (2014) (33)
- Nutritional Aspects of Spermidine. (2020) (33)
- Ferroptosis becomes immunogenic: implications for anticancer treatments (2020) (33)
- [Immunological aspects of anticancer chemotherapy]. (2008) (33)
- CD103+ dendritic cells producing interleukin-12 in anticancer immunosurveillance. (2014) (33)
- Trial watch: dietary interventions for cancer therapy (2019) (33)
- The anticancer peptide RT53 induces immunogenic cell death (2018) (33)
- PGC-1β mediates adaptive chemoresistance associated with mitochondrial DNA mutations (2013) (33)
- Apoptosis and cell cycle: distinct checkpoints with overlapping upstream control. (2000) (32)
- Human and mouse MOK2 proteins are associated with nuclear ribonucleoprotein components and bind specifically to RNA and DNA through their zinc finger domains (1997) (32)
- Extracellular SQSTM1 mediates bacterial septic death in mice through insulin receptor signalling (2020) (32)
- Methods to dissect mitochondrial membrane permeabilization in the course of apoptosis. (2008) (32)
- Direct molecular interactions between Beclin 1 and the canonical NFκB activation pathway (2012) (32)
- [Mitotic catastrophe: a special case of apoptosis]. (2004) (32)
- Whole-genome duplication increases tumor cell sensitivity to MPS1 inhibition (2015) (32)
- Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death (2018) (32)
- Flt3 receptor inhibition reduces constitutive NFκB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia (2008) (32)
- High level of Bcl-2 counteracts apoptosis mediated by a live rabies virus vaccine strain and induces long-term infection. (2003) (32)
- Trial Watch: Adoptive cell transfer for oncological indications (2015) (32)
- When less is more: hormesis against stress and disease (2014) (31)
- Microbiota-Centered Interventions: The Next Breakthrough in Immuno-Oncology? (2021) (31)
- Autocrine signaling of type 1 interferons in successful anticancer chemotherapy (2015) (31)
- A revolution in apoptosis: from a nucleocentric to a mitochondriocentric perspective. (1998) (31)
- Synthetic induction of immunogenic cell death by genetic stimulation of endoplasmic reticulum stress (2014) (31)
- Apaf-1 Deficiency Causes Chromosomal Instability (2007) (31)
- Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy (2020) (31)
- Trial Watch (2013) (31)
- Autophagy and innate immunity ally against bacterial invasion (2011) (31)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- Autophagy in Ras-induced malignant transformation: fatal or vital? (2011) (31)
- Glucocorticoid-regulated gene expression in the immune system. Analysis of glucocorticoid-regulated transcripts from the mouse macrophage-like cell line P388D1. (1990) (31)
- Identification of pharmacological agents that induce HMGB1 release (2017) (31)
- Cross‐linking of surface IgM or IgD causes differential biological effects in spite of overlap in tyrosine (de)phosphorylation profile (1992) (31)
- A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint (2009) (31)
- Autophagy is induced by ischemic preconditioning in human livers formerly treated by chemotherapy to limit necrosis (2010) (30)
- 2012 Landes Bioscience. Do not distribute. Abscopal but desirable The contribution of immune responses to the efficacy of radiotherapy (2012) (30)
- Abscopal but desirable (2012) (30)
- The HERV-K Human Endogenous Retrovirus Envelope Protein Antagonizes Tetherin Antiviral Activity (2014) (30)
- MITOCHONDRIAL PERMEABILIZATION IN CELL DEATH (2007) (30)
- Secondary Necrosis: Accidental No More. (2017) (30)
- Trial Watch: Immunostimulatory monoclonal antibodies for oncological indications (2017) (30)
- Preapoptotic Chromatin Condensation Upstream of the Mitochondrial Checkpoint* (2004) (29)
- The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells. (2009) (29)
- Anticancer effects of anti-CD47 immunotherapy in vivo (2018) (29)
- Independent transcriptional reprogramming and apoptosis induction by cisplatin (2012) (29)
- Nuclear Localization of Apoptosis Protease Activating Factor-1 Predicts Survival after Tumor Resection in Early-Stage Non–Small Cell Lung Cancer (2004) (29)
- p53-A pro-apoptotic signal transducer involved in AIDS. (2005) (29)
- Trial Watch (2014) (29)
- Change in HER2 (ERBB2) gene status after taxane-based chemotherapy for breast cancer: polyploidization can lead to diagnostic pitfalls with potential impact for clinical management. (2013) (29)
- Cancer: Antibodies regulate antitumour immunity (2015) (29)
- Trial watch: Naked and vectored DNA-based anticancer vaccines (2015) (29)
- Mitochondrial Cell Death Control in Familial Parkinson Disease (2007) (29)
- Trial watch (2013) (29)
- Suppression of tumor antigen presentation during aneuploid tumor evolution contributes to immune evasion (2019) (29)
- Prognostic impact of the expression of NCR1 and NCR3 NK cell receptors and PD-L1 on advanced non-small cell lung cancer (2017) (29)
- PARP and other prospective targets for poisoning cancer cell metabolism. (2014) (28)
- Pharmacological inhibition of fatty-acid oxidation synergistically enhances the effect of l-asparaginase in childhood ALL cells (2016) (28)
- Autophagy in the cancer-immunity dialogue. (2020) (28)
- Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death (2010) (28)
- TG2 regulates the heat‐shock response by the post‐translational modification of HSF1 (2018) (28)
- hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway (2013) (28)
- Detection of apoptosis and apoptosis-associated alterations (1996) (28)
- Contribution of IL-17-producing gammadelta T cells to the efficacy of anticancer chemotherapy. (2020) (28)
- Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE 1 α signaling (2018) (28)
- Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size. (2000) (28)
- Trial watch (2005) (28)
- Metabolomic analyses reveal that anti-aging metabolites are depleted by palmitate but increased by oleate in vivo (2015) (28)
- Trans-Fats Inhibit Autophagy Induced by Saturated Fatty Acids (2018) (28)
- Vitamin B6 metabolism influences the intracellular accumulation of cisplatin (2013) (27)
- Karyotypic Aberrations in Oncogenesis and Cancer Therapy. (2015) (27)
- Caspase independence of radio-induced cell death (2006) (27)
- Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress (2010) (27)
- Pertussis toxin inhibits activation-induced cell death of human thymocytes, pre-B leukemia cells and monocytes (1994) (27)
- Combinatorial immunotherapy with checkpoint blockers solves the problem of metastatic melanoma—An exclamation sign with a question mark (2015) (27)
- Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals (2009) (26)
- Tumor necrosis factor is dispensable for the success of immunogenic anticancer chemotherapy (2013) (26)
- Syncytial apoptosis signaling network induced by the HIV-1 envelope glycoprotein complex: an overview (2015) (26)
- Acyl-CoA-binding protein (ACBP): a phylogenetically conserved appetite stimulator (2020) (26)
- Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti‐Vβ8 antibodies (1992) (26)
- Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate. (2019) (26)
- Metabolic alterations in plasma from patients with familial and idiopathic Parkinson’s disease (2020) (26)
- Tantalizing Thanatos: unexpected links in death pathways. (2002) (26)
- Contribution of humoral immune responses to the antitumor effects mediated by anthracyclines (2013) (26)
- A multiplicity of cell death pathways. Symposium on apoptotic and non-apoptotic cell death pathways. (2007) (26)
- Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis (2021) (26)
- Immunophenotyping of Stage III Melanoma Reveals Parameters Associated with Patient Prognosis. (2016) (26)
- Ipr T cells vaccinate against lupus in MRL/lpr mice (1992) (26)
- TNFR2/BIRC3-TRAF1 signaling pathway as a novel NK cell immune checkpoint in cancer (2017) (26)
- Multifaceted roles of purinergic receptors in viral infection. (2012) (26)
- Spermidine reduces cancer-related mortality in humans (2018) (26)
- A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice. (1994) (26)
- Can the exome and the immunome converge on the design of efficient cancer vaccines? (2012) (26)
- Contagious apoptosis facilitated by the HIV-1 envelope: fusion-induced cell-to-cell transmission of a lethal signal (2004) (26)
- Heat Shock Protein 70 Neutralizes Apoptosis-Inducing Factor (2001) (26)
- DRAM: A phylogenetically ancient regulator of autophagy (2009) (26)
- Shigella targets the mitochondrial checkpoint of programmed necrosis. (2009) (26)
- IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms (2021) (26)
- Immunological Self‐Tolerance: An Analysis Employing Cytokines or Cytokine Receptors Encoded by Transgenes or a Recombinant Vaccinia Virus (1991) (26)
- Structure and expression of a chicken MHC class I gene (2005) (25)
- Oncogenic KRAS blockade therapy: renewed enthusiasm and persistent challenges (2021) (25)
- Natural killer cell mediated immunosurveillance of pediatric neuroblastoma (2015) (25)
- TFAM is a novel mediator of immunogenic cancer cell death (2018) (25)
- MouseVk gene classification by nucleic acid sequence similarity (2006) (25)
- Caspase 2 in mitotic catastrophe: The terminator of aneuploid and tetraploid cells (2017) (25)
- Integration of host-related signatures with cancer cell-derived predictors for the optimal management of anticancer chemotherapy. (2010) (25)
- Insights into the Mitochondrial Signaling Pathway: What Lessons for Chemotherapy? (2003) (25)
- Immunogenetic analysis of spontaneous autoimmune thyroiditis of obese strain chickens. (1989) (25)
- Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1 (2004) (25)
- Pharmacological inhibition of mitochondrial membrane permeabilization for neuroprotection (2009) (25)
- Nuclear accumulation of HMG1 protein is correlated to DNA synthesis (1986) (25)
- The oncolytic peptide LTX-315 triggers necrotic cell death (2015) (25)
- Trial watch: IDO inhibitors in cancer therapy (2020) (25)
- Toll like receptor 7 expressed by malignant cells promotes tumor progression and metastasis through the recruitment of myeloid derived suppressor cells (2018) (25)
- Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice (2020) (24)
- Trial Watch (2004) (24)
- Trial watch (2006) (24)
- ER stress in Cardiometabolic Diseases: from Molecular Mechanisms to Therapeutics. (2021) (24)
- An anticancer therapy-elicited immunosurveillance system that eliminates tetraploid cells (2013) (24)
- The Captured Retroviral Envelope syncytin-A and syncytin-B Genes Are Conserved in the Spalacidae Together with Hemotrichorial Placentation1 (2014) (24)
- The fail-safe paradigm of immunological self-tolerance (1991) (24)
- Trial watch: DNA-based vaccines for oncological indications (2017) (24)
- Systemic autophagy in the therapeutic response to anthracycline-based chemotherapy (2018) (24)
- Apoptosis Inversely Correlates with Rabies Virus Neurotropism (2003) (24)
- Involvement of apoptosis‐inducing factor during dolichyl monophosphate‐induced apoptosis in U937 cells (2000) (24)
- Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis. (2006) (24)
- Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: Role of caspase-8 and mitochondria (2002) (24)
- SnapShot: Macroautophagy (2008) (24)
- A p53-regulated immune checkpoint relevant to cancer (2015) (24)
- Some properties of a Ca2+- and (or) Mg2+-requiring nucleoside di- and tri-phosphatase(s) associated with the membranes of rat pancreatic zymogen granules. (1978) (24)
- Spermidine promotes mating and fertilization efficiency in model organisms (2013) (24)
- Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming (2022) (24)
- Emerging mechanisms of immunocoagulation in sepsis and septic shock. (2021) (23)
- A phase I/II trial of Erlotinib in higher risk myelodysplastic syndromes and acute myeloid leukemia after azacitidine failure. (2014) (23)
- Impact of chemotactic factors and receptors on the cancer immune infiltrate: a bioinformatics study revealing homogeneity and heterogeneity among patient cohorts (2018) (23)
- NAD+ Metabolism in Cardiac Health, Aging, and Disease. (2021) (23)
- Tumor lysis with LTX-401 creates anticancer immunity (2019) (23)
- Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo (2021) (23)
- Actinomycin D Targets NPM1c-Primed Mitochondria to Restore PML-Driven Senescence in AML Therapy (2021) (22)
- Aspirin—another caloric-restriction mimetic (2018) (22)
- Selective interactions of human kin17 and RPA proteins with chromatin and the nuclear matrix in a DNA damage- and cell cycle-regulated manner. (2003) (22)
- Purification and liposomal reconstitution of permeability transition pore complex. (2000) (22)
- Cytokines in oncolytic virotherapy. (2020) (22)
- Intratumoral Immunization by p19Arf and Interferon-β Gene Transfer in a Heterotopic Mouse Model of Lung Carcinoma12 (2016) (22)
- Human Immunodeficiency Virus 1 Envelope Glycoprotein Complex-induced Apoptosis Involves Mammalian Target of Rapamycin / FKBP 12-Rapamycin – associated Protein – mediated p 53 Phosphorylation (2001) (22)
- RIP3 attenuates the pancreatic damage induced by deletion of ATG7 (2017) (22)
- Protein kinase C isoenzymes display differential affinity for phorbol esters. Analysis of phorbol ester receptors in B cell differentiation. (1992) (22)
- Critical role for TRIM28 and HP1β/γ in the epigenetic control of T cell metabolic reprograming and effector differentiation (2019) (22)
- Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging (2021) (21)
- OncoImmunology: a new journal at the frontier between oncology and immunology (2012) (21)
- The cell biology of apoptosis: Evidence for the implication of mitochondria (1996) (21)
- Crizotinib – a tyrosine kinase inhibitor that stimulates immunogenic cell death (2019) (21)
- Trial Watch: Proteasomal inhibitors for anticancer therapy (2014) (21)
- Decelerating ageing and biological clocks by autophagy (2019) (21)
- Involvement of autophagy in NK cell development and function (2017) (21)
- Death, danger, and immunity: an infernal trio (2007) (21)
- Anticancer effects of imatinib via immunostimulation (2011) (21)
- DCN released from ferroptotic cells ignites AGER-dependent immune responses (2021) (21)
- HIV-1 protease inhibitors and cytomegalovirus vMIA induce mitochondrial fragmentation without triggering apoptosis (2006) (21)
- Negative prognostic value of high levels of intracellular poly(ADP-ribose) in non-small cell lung cancer. (2015) (21)
- PF558 THE ANTI-BCMA ANTIBODY-DRUG CONJUGATE GSK2857916 DRIVES IMMUNOGENIC CELL DEATH AND IMMUNE-MEDIATED ANTI-TUMOR RESPONSES, AND IN COMBINATION WITH AN OX40 AGONIST POTENTIATES IN VIVO ACTIVITY (2019) (21)
- Interferon induction of chicken MHC class I gene expression: phylogenetic conservation of the interferon-responsive element. (1992) (20)
- Insights into autoimmunity: from classical models to current perspectives. (1990) (20)
- Towards a rational combination therapy of cystic fibrosis (2013) (20)
- HIV-1 Envelope Overcomes NLRP3-Mediated Inhibition of F-Actin Polymerization for Viral Entry. (2019) (20)
- Involvement of the interleukin 4 pathway in the generation of functional gamma delta T cells from human pro-T cells. (1991) (20)
- CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways. (1996) (20)
- Peroxisome: the new player in ferroptosis (2020) (20)
- Mitochondrial Dynamics: A Strategy for Avoiding Autophagy (2011) (20)
- Inhibition of formyl peptide receptor 1 reduces the efficacy of anticancer chemotherapy against carcinogen-induced breast cancer (2016) (20)
- A higher spirit: avoiding yeast suicide during alcoholic fermentation (2012) (20)
- Cancer therapy: Altering mitochondrial properties. (2014) (20)
- α-Ketoglutarate inhibits autophagy (2019) (19)
- Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells (2010) (19)
- Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR (2018) (19)
- Trial Watch (2013) (19)
- Interferon-γ induces cancer cell ferroptosis (2019) (19)
- Caloric restriction mimetics for the treatment of cardiovascular diseases. (2020) (19)
- The oncolytic compound LTX-401 targets the Golgi apparatus (2016) (19)
- Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia (2017) (19)
- Trial watch : the gut microbiota as a tool to boost the clinical efficacy of anticancer immunotherapy (2020) (19)
- The Role of Micro-RNAs and Circulating Tumor Markers as Predictors of Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer (2020) (19)
- Diacylglycerol triggers Rim101 pathway–dependent necrosis in yeast: a model for lipotoxicity (2017) (19)
- Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients (2010) (19)
- High-Throughput Quantification of GFP-LC3+ Dots by Automated Fluorescence Microscopy. (2017) (19)
- Genetic organization of the chicken MHC (1990) (19)
- Therapy-induced microenvironmental changes in cancer (2016) (19)
- Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis (2022) (18)
- Defective Autophagy Initiates Malignant Transformation. (2016) (18)
- Novel insights into the mitochondrial permeability transition (2014) (18)
- Trial watch (2006) (18)
- Endoplasmic Reticulum Stress in Liver Diseases. (2022) (18)
- The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope (2009) (18)
- An atypical caspase-independent death pathway for an immunogenic cancer cell line (2002) (18)
- Autophagy in metabolism and quality control: opposing, complementary or interlinked functions? (2021) (18)
- Chemical activation of SAT1 corrects diet-induced metabolic syndrome (2020) (18)
- Vital function of PRELI and essential requirement of its LEA motif (2010) (18)
- Does prothymosin-α act as molecular switch between apoptosis and autophagy? (2003) (18)
- A histone point mutation that switches on autophagy (2014) (18)
- Participation of kin17 protein in replication factories and in other DNA transactions mediated by high molecular weight nuclear complexes. (2003) (18)
- Metabolic interactions between cysteamine and epigallocatechin gallate (2017) (18)
- Prognostic value of LIPC in non-small cell lung carcinoma (2013) (17)
- The GLN Family of Murine Endogenous Retroviruses Contains an Element Competent for Infectious Viral Particle Formation (2008) (17)
- Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis (2019) (17)
- Trial watch (2005) (17)
- Lurbinectedin: an FDA-approved inducer of immunogenic cell death for the treatment of small-cell lung cancer (2020) (17)
- The ambiguous role of FPR1 in immunity and inflammation (2020) (17)
- When death was young: an ancestral apoptotic network in bacteria. (2012) (17)
- Constitutive presence of cytochrome c in the cytosol of a chemoresistant leukemic cell line (2005) (17)
- Cancer induces a stress ileopathy depending on B-adrenergic receptors and promoting dysbiosis that contribute to carcinogenesis. (2021) (17)
- Reverse Warburg: Straight to cancer (2012) (17)
- Localization of T‐antigen on simian virus 40 minichromosomes by immunoelectron microscopy. (1984) (17)
- Pharmacological inhibitors of anaplastic lymphoma kinase (ALK) induce immunogenic cell death through on-target effects (2021) (17)
- Quantification of cellular viability by automated microscopy and flow cytometry (2015) (17)
- Mitochondrial control of cell death induced by hyperosmotic stress (2006) (16)
- Methionine restriction for improving progeria: another autophagy-inducing anti-aging strategy? (2018) (16)
- Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione (2016) (16)
- Bacterial infection and non-Hodgkin’s lymphoma (2020) (16)
- Bacterial Invasion: Linking Autophagy and Innate Immunity (2010) (16)
- Contribution of annexin A1 to anticancer immunosurveillance (2019) (16)
- Yet another pattern recognition receptor involved in the chemotherapy-induced anticancer immune response: Formyl peptide receptor-1 (2016) (16)
- Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux (2019) (16)
- How many genes code for organ-specific autoimmunity? (1990) (16)
- Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia–ischemia (2018) (16)
- A metabolic master regulator of autophagy and longevity (2014) (16)
- Witch Hunt against Tumor Cells Enhanced by Dendritic Cells (2009) (16)
- Pertussis toxin‐sensitive GTP‐binding proteins regulate activation‐induced apoptotic cell death of human natural killer cells (1995) (16)
- Functional double‐negative T cells in the periphery express T cell receptor Vβ gene products that cause deletion of single‐positive T cells (1993) (16)
- Immunological effects of chemotherapy in spontaneous breast cancers (2013) (16)
- Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C. (2004) (16)
- Non-nucleolar transcription complexes of rat liver as revealed by spreading isolated nuclei. (1979) (16)
- Immunostimulatory gut bacteria (2019) (16)
- The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis (2017) (16)
- The dark side of ferroptosis in pancreatic cancer (2021) (15)
- Failure of apoptosis-inducing factor to act as neuroglobin reductase. (2009) (15)
- Recruitment of LC3 to damaged Golgi apparatus (2018) (15)
- Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells (2006) (15)
- Copper – a novel stimulator of autophagy (2020) (15)
- Cell death mechanisms in HIV-associated dementia: the involvement of syncytia (2005) (15)
- GD3 ganglioside as an intracellular mediator of apoptosis. (2000) (15)
- Corrigendum: “Combinatorial Strategies for the Induction of Immunogenic Cell Death” (2015) (15)
- Immunosurveillance in esophageal carcinoma: The decisive impact of regulatory T cells (2016) (15)
- Novel inducers of BECN1-independent autophagy: cis-unsaturated fatty acids (2015) (15)
- A TLR3 ligand reestablishes chemotherapeutic responses in the context of FPR1 deficiency. (2020) (15)
- Chlamydia trachomatis fails to protect its growth niche against pro-apoptotic insults (2018) (15)
- Pattern of cytokine expression in circulation CD57+ T cells from long-term renal allograft recipients. (1998) (15)
- The alternative RelB NF-κB subunit is a novel critical player in diffuse large B-cell lymphoma. (2021) (15)
- Use of Protein Biotinylation In Vivo for Immunoelectron Microscopic Localization of a Specific Protein Isoform (2008) (15)
- Acyl-CoA-binding protein (ACBP): the elusive ‘hunger factor' linking autophagy to food intake (2019) (15)
- Identification of pharmacological inhibitors of conventional protein secretion (2018) (15)
- Trypsin-Mediated Sensitization to Ferroptosis Increases the Severity of Pancreatitis in Mice (2021) (15)
- Vitamin B6 improves the immunogenicity of cisplatin-induced cell death (2014) (15)
- Erratum to: Flt3 receptor inhibition reduces constitutive NFκB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia (2008) (15)
- Apoptosis in Immunology (1995) (15)
- GENETIC ANALYSIS OF EXTRATHYROIDAL FEATURES OF OBESE STRAIN (OS) CHICKENS WITH SPONTANEOUS AUTOIMMUNE THYROIDITIS (1988) (15)
- Introduction: the immune response against dying cells. (2008) (15)
- Old Paradoxes and New Opportunities for Appetite Control in Obesity (2021) (15)
- Necroptosis turns TNF lethal. (2011) (15)
- Endoplasmic reticulum stress in the cellular release of damage-associated molecular patterns. (2020) (14)
- Analysis of the hamster polyomavirus infection in vitro: host-restricted productive cycle. (1990) (14)
- Autophagy-mediated metabolic effects of aspirin (2020) (14)
- Reply: Immunosuppressive cell death in cancer (2017) (14)
- The multifaceted granulysin. (2010) (14)
- Defective proteostasis in celiac disease as a new therapeutic target (2019) (14)
- Does prothymosin-alpha act as molecular switch between apoptosis and autophagy? (2003) (14)
- Re-examining the role of cytochrome c in cell death (2008) (14)
- The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate (2016) (14)
- Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism (2014) (14)
- Artificial tethering of LC3 or p62 to organelles is not sufficient to trigger autophagy (2019) (14)
- Redox activity of AIF 1 Mo : 10498 NADH-oxidase activity of mitochondrial apoptosis-inducing factor ( AIF ) (2001) (14)
- Trial watch: intratumoral immunotherapy (2021) (13)
- Interleukin-2: a possible trigger for autoimmunity. (1992) (13)
- Inhibition of autophagy by TAB 2 and TAB 3 (2011) (13)
- Metformin: a metabolic modulator (2017) (13)
- Differences in the composition of the immune infiltrate in breast cancer, colorectal carcinoma, melanoma and non-small cell lung cancer: A microarray-based meta-analysis (2016) (13)
- Autophagy extends lifespan via vacuolar acidification (2014) (13)
- Biomarkers of immunogenic stress in metastases from melanoma patients: Correlations with the immune infiltrate (2016) (13)
- Cell-autonomous, paracrine and neuroendocrine feedback regulation of autophagy by DBI/ACBP (diazepam binding inhibitor, acyl-CoA binding protein): the obesity factor (2019) (13)
- Intra-thymic nurse cell lymphocytes can induce a graft-versus-host reaction with high efficiency. (1989) (13)
- Melanoma and immunotherapy bridge 2015 (2016) (13)
- Lysosomotropic agents including azithromycin, chloroquine and hydroxychloroquine activate the integrated stress response (2021) (13)
- Dying to survive - apoptosis, necroptosis, autophagy as supreme experiments of nature. (2015) (13)
- Regulatory approval of photoimmunotherapy: photodynamic therapy that induces immunogenic cell death (2020) (13)
- Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors (2016) (13)
- Inhibition of autophagy by TAB 2 and TAB 3 (2011) (13)
- Circulating CASK is associated with recurrent focal segmental glomerulosclerosis after transplantation (2019) (13)
- B709 Mitochondrial Control of Cell Death (2001) (13)
- Fasting improves anticancer immunosurveillance via autophagy induction in malignant cells (2016) (13)
- A transcriptional signature associated with non-Hodgkin lymphoma in the blood of patients with Q fever (2019) (13)
- T cell Bispecific Antibodies in Node-Positive Breast Cancer: Novel Therapeutic Avenue for MHC class I Loss Variants. (2019) (13)
- 53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope (2010) (13)
- A long non-coding RNA links calreticulin-mediated immunogenic cell removal to RB 1 transcription (2015) (13)
- GSK3-mediated VDAC phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation (2012) (13)
- Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. (2019) (13)
- CHCHD4 links AIF to the biogenesis of respiratory chain complex I (2016) (13)
- Positive impact of autophagy in human breast cancer cells on local immunosurveillance (2016) (13)
- The beauty of death. (2002) (13)
- Interleukin-2, a pro-autoimmune lymphokine that interferes with post-deletional tolerance. (1992) (13)
- Immune contexture of cholangiocarcinoma. (2019) (12)
- Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells (2020) (12)
- Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells. (2010) (12)
- Aspirin induces autophagy via inhibition of the acetyltransferase EP300 (2018) (12)
- Immune effectors responsible for the elimination of hyperploid cancer cells (2018) (12)
- FADD: an endogenous inhibitor of RIP3-driven regulated necrosis (2011) (12)
- Cell Senescence (2013) (12)
- Circular RNAs as Potential Biomarkers in Breast Cancer (2022) (12)
- Lysosome-targeting agents in cancer therapy (2017) (12)
- Oncolysis with DTT-205 and DTT-304 generates immunological memory in cured animals (2018) (12)
- Unexpected role of the phosphate carrier in mitochondrial fragmentation (2008) (12)
- BH 3-only proteins are part of a regulatory network that control the sustained signaling of the Unfolded Protein Response sensor IRE 1 α (2010) (12)
- The role of interleukin 2 in the development of autoimmune thyroiditis. (1992) (12)
- Evaluation of rapamycin-induced cell death. (2012) (12)
- Metabolic enzymes expressed by cancer cells impact the immune infiltrate (2019) (12)
- Trial watch (2013) (12)
- A novel treatment of cystic fibrosis acting on-target: cysteamine plus epigallocatechin gallate for the autophagy-dependent rescue of class II-mutated CFTR (2016) (12)
- A human mitochondriopathy caused by AIF mutation (2010) (12)
- Immunological Effects of Epigenetic Modifiers (2019) (12)
- Multifaceted modes of action of the anticancer probiotic Enterococcus hirae (2021) (12)
- Tumor-intrinsic determinants of immunogenic cell death modalities (2021) (12)
- Improvement of immunogenic chemotherapy by STAT3 inhibition (2016) (12)
- Morphometric analysis of immunoselection against hyperploid cancer cells (2015) (12)
- Differentiating megakaryocytes in myelodysplastic syndromes succumb to mitochondrial derangement without caspase activation (2007) (12)
- STAT3 inhibition for cancer therapy: Cell-autonomous effects only? (2016) (12)
- Highly Efficient Expression of Proteins Encoded by Recombinant Vaccinia Virus in Lymphocytes (1991) (12)
- A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects (2020) (12)
- Immunosurveillance against cancer-associated hyperploidy (2012) (11)
- Potent immunosuppressive effects of the oncometabolite R-2-hydroxyglutarate (2018) (11)
- Cytokine-like protein 1-induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML. (2021) (11)
- Redaporfin induces immunogenic cell death by selective destruction of the endoplasmic reticulum and the Golgi apparatus (2018) (11)
- Prime time for immune-checkpoint targeted therapy at ASCO 2015 (2016) (11)
- Fine-Tuning Cardiac Insulin-Like Growth Factor 1 Receptor Signaling to Promote Health and Longevity (2022) (11)
- Developmental Expression of IL-2-Receptor Light Chain (CD25) in the Chicken Embryo (1991) (11)
- Epigenetic anticancer agents cause HMGB1 release in vivo (2018) (11)
- Paradoxical Inhibition of Glycolysis by Pioglitazone Opposes the Mitochondriopathy Caused by AIF Deficiency (2017) (11)
- The gliadin-CFTR connection: new perspectives for the treatment of celiac disease (2019) (11)
- Targeting dendritic cell metabolism in cancer (2010) (11)
- The role of mitochondria in apoptosis (1999) (11)
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- Vital functions of Apoptosis Inducing Factor (AIF) (2009) (1)
- Is ferroptosis immunogenic? The devil is in the details! (2022) (1)
- MPA/DMBA-driven mammary carcinomas. (2021) (1)
- Multiplexed quantification of autophagic flux by imaging flow cytometry. (2021) (1)
- Cancer: Defeating the immortal (2007) (1)
- Autophagic flux assessment by immunoblot. (2021) (1)
- Assessment of transcription inhibition as a characteristic of immunogenic cell death. (2022) (1)
- The scent of death: a metabolic goodbye signal emitted by dying cells (2020) (1)
- High plasma concentrations of acyl‐coenzyme A binding protein (ACBP) predispose to cardiovascular disease: Evidence for a phylogenetically conserved proaging function of ACBP (2022) (1)
- Trial watch: Toll-like receptor ligands in cancer therapy (2023) (1)
- The fabulous legacy of a Nobel Prize Laureate (2012) (1)
- Maintenance of the T lymphocyte pool by inhibition of apoptosis: a novel strategy of immunostimulation? (1995) (1)
- The novel retinoid AHPN/CD437 can trigger apoptosis through a mitochondrial pathway independent of the nucleus. (1999) (1)
- 2603 : Caspase-Independence of Radioinduced Cell Death in Hct116 Human Colorectal Tumor Cell Lines (2006) (1)
- Dying cell recognition shapes the pathophysiology of cell death (2016) (1)
- Alpha-synuclein kills aged yeast depending on mitochondrial function (2009) (1)
- Personalization of therapies in rare diseases: a translational approach for the treatment of cystic fibrosis. (2019) (1)
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- Quantification of eIF2α Phosphorylation Associated with Mitotic Catastrophe by Immunofluorescence Microscopy. (2021) (1)
- Ghrelin and leptin regulating wound healing. (2022) (1)
- A pharyngeal jaw evolutionary innovation facilitated extinction in Lake Victoria cichlids (2015) (1)
- Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy (2020) (1)
- Studies Immune In fi ltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors (2013) (1)
- Erratum: The oncolytic compound LTX-401 targets the Golgi apparatus. (2018) (1)
- Viperin turns coat in cytomegalovirus infection. (2011) (1)
- NAD+ depletion enhances reovirus-induced oncolysis in multiple myeloma (2022) (1)
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- Publisher Correction: Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer (2020) (1)
- The Mitochondrion as a Sensor/Effector of Oxidative Stress During Apoptosis (1997) (1)
- Co-ordinated mitochondrial degradation by autophagy and heterophagy in cardiac homeostasis. (2021) (1)
- Correction for Gyrd-Hansen et al., “Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9” (2017) (1)
- Ketosis versus carbotoxicity – metabolism determines the outcome of cancer immunotherapy (2021) (1)
- The Capacity of the Hypomethylating Agents Azacytidine and Decitabine to Induce Apoptosis and Cell Cycle Arrest Depends on the Activation of the DNA-Damage Response Pathway. (2008) (1)
- [Be oneself eatable, in moderation, a condition to keep a healthy spirit in a healthy body]. (2017) (1)
- Increased Proliferation Induced by Constitutive Activation of the Src-Kinase Lyn and Aberrant mTOR Signaling in AML Is Abrogated by the EGFR-Inhibitor Erlotinib. (2009) (1)
- Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network (2022) (1)
- Novel immune checkpoint blocker to treat Merkel cell carcinoma (2017) (1)
- A novel tool for detecting lysosomal membrane permeabilization by high-throughput fluorescence microscopy. (2021) (1)
- Microenvironment and Immunology CCL 2 / CCR 2-Dependent Recruitment of Functional Antigen-Presenting Cells into Tumors upon Chemotherapy (2014) (1)
- PARP1 inhibition elicits immune responses against non-small cell lung cancer (2022) (1)
- The scent of death: a metabolic goodbye signal emitted by dying cells (2020) (1)
- ADP-Ribosylation Factor-Like 8B (2012) (1)
- Mitochondrial Localization and Function of the Purinergic Receptor P2X7 (2021) (1)
- Effects of the intestinal microbiota on prostate cancer treatment by androgen deprivation therapy (2022) (1)
- Spontaneous autoimmune thyroiditis: new therapeutic strategies. (1990) (1)
- Translocation of chromatin proteins to nucleoli—The influence of protein dynamics on post‐fixation localization (2021) (1)
- A loss-of-function polymorphism in ATG16L1 compromises therapeutic outcome in head and neck carcinoma patients (2022) (1)
- A nanoparticle-based tour de force for enhancing immunogenic cell death elicited by photodynamic therapy (2022) (1)
- Calreticulin Exposure in Mitotic Catastrophe. (2021) (1)
- Mechanisms of Immunological Self-Tolerance (1994) (1)
- Non-apoptotic functions of apoptosis-regulatory (2012) (1)
- Local anesthetics and immunotherapy: a novel combination to fight cancer (2022) (1)
- Experimental Models of Septic Shock in the Mouse: The Effect of Linomide (1995) (1)
- Apoptosis — Searching for the Central Executioner (2000) (1)
- Abstract 4563: Local and abscopal effects in oncolytic virotherapy are boosted by immune checkpoint blockade, immunogenic chemotherapy, or IFNAR blockade (2017) (1)
- Immunogenic stress induced by local anesthetics injected into neoplastic lesions (2022) (1)
- Disruption of Bcl-2 Heterodimerization by the BH3 Mimetic ABT-737 Restores Spontaneous Apoptosis and Induces Differentiation in High Risk MDS and AML. (2007) (1)
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- Roles of Mitochondria in Apoptosis (1999) (0)
- Vogels Pathways and Memory Networks Inhibitory Plasticity Balances Excitation and Inhibition in Sensory (2012) (0)
- A Fluorescence-Microscopic System for Monitoring the Turnover of the Autophagic Substrate p62/SQSTM1. (2022) (0)
- Complement interaction with cells undergoing immunogenic cell death (2017) (0)
- Molecular basis of the immunogenicity of cell death during chemotherapy (2008) (0)
- Organs on chip approach: a tool to evaluate cancer -immune cells interactions (2017) (0)
- Discovery of a druggable copper-signaling pathway that drives cell plasticity and inflammation (2022) (0)
- An immunosurveillance mechanism controls cancer cell ploidy. Supplementary Material. (2013) (0)
- Publisher Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis (2018) (0)
- Assessment of immunological memory formation in vivo. (2023) (0)
- Interferon-γ induces cancer cell ferroptosis (2019) (0)
- News and Thoughts Copper – a novel stimulator of autophagy (2020) (0)
- The Immune System and Immune Modulation (2020) (0)
- Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response (2020) (0)
- The place of mitochondria in apoptosis (2001) (0)
- Crizotinib-induced immunogenic cell death in non-small cell lung cancer (2019) (0)
- Immunogenic cell death in cancer: concept and therapeutic implications (2023) (0)
- Anti-CTLA-4 immunotherapy: uncoupling toxicity and efficacy (2018) (0)
- The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species (2019) (0)
- Sustained Type I interferon signaling as a mechanism of resistance to PD-1 blockade (2019) (0)
- Melanoma and immunotherapy bridge 2015 (2016) (0)
- Abstract CT108: A phase I dose escalation study of intra-tumoral LTX-315 as monotherapy or in combination with either ipilimumab or pembrolizumab in patients with transdermally accessible tumors (NCT01986426) (2017) (0)
- Autophagy suppresses the pathogenic immune response to dietary antigens in cystic fibrosis (2019) (0)
- Identification of pharmacological agents that induce HMGB1 release (2017) (0)
- Erratum to: Mitochondrial control of cell death induced by hyperosmotic stress (2013) (0)
- Clinical Studies Immune In fi ltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors (2013) (0)
- Spermidine rejuvenates T lymphocytes and restores anticancer immunosurveillance in aged mice (2022) (0)
- 618 POSTER A novel tyrosine kinase inhibitor exhibits significant anti-proliferative/pro-apoptotic effects in non-small cell lung cancer models (2006) (0)
- The Matrix Protein of Vesicular Stomatitis Virus Binds Dynamin for Efficient Viral Assembly (cid:1) (2010) (0)
- 1 Mitochondrial proteins containing coiled-coil-helix-coiled-coil-helix ( CHCH ) domains in health and disease (2016) (0)
- High throughput screening for autophagy. (2021) (0)
- Atrophy , and Dilated Cardiomyopathy Mitochondrial Dysfunction , Skeletal Muscle Apoptosis-Inducing Factor Leads to Muscle-Specific Loss of (2005) (0)
- Accumulation of Basic Am ino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin Graphical (2015) (0)
- P1582Dietary spermidine ameliorates hypertension and prevents diastolic dysfunction in Dahl salt-sensitive rats (2017) (0)
- The HIV-1 auxiliary protein Vpr induces apoptosis via a direct effect on mitochondria. (1999) (0)
- Oncogenic KRAS blockade therapy: renewed enthusiasm and persistent challenges (2021) (0)
- Abstract 3115: PARP overactivation predicts the susceptibility of human cancer cells to apoptosis induction by PARP inhibitors (2012) (0)
- Contents, Vol. 97, 1992 (1992) (0)
- amplification Megakaryocyte polyploidization is associated with a functional gene (2013) (0)
- Molecular and Metabolic Cues of the Key-Lock Paradigm Dictating Immunogenic Cell Death (2014) (0)
- DNA topoisomeraes fromratlver: physoloa vaiations (1983) (0)
- Erlotinib Inhibits ABC Transporters of AML Progenitors with Stem Cell Features and Increases Chemosensitivity to Current AML Drugs (2010) (0)
- A novel dendritic cell subset supporting the concept of tumor immunoediting: IFN producing Killer Dendritic cell (IKDC) (2006) (0)
- megakaryocytes Platelet formation is the consequence of caspase activation within (2013) (0)
- The European Cell Death Group (2001) (0)
- Gist natural killers (2011) (0)
- Homotypic cell cannibalism, a cell‐death process regulated by the nuclear protein 1, opposes to metastasis in pancreatic cancer (2021) (0)
- Guest Editor (2004) (0)
- Cardiac PI3K p110α attenuation delays aging and extends lifespan (2022) (0)
- Adenylyl Cyclase Inhibitory Gi Alpha Subunit (2012) (0)
- Abstract 1353: Immunomodulatory effects of valproic acid in combination with cisplatin and cetuximab in head and neck squamous cell carcinoma (2022) (0)
- Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer (2023) (0)
- Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death (2018) (0)
- Premitochondrial Step of Thymocyte Apoptosis Proteasome Activation Occurs at an Early, (1998) (0)
- THE MITOCHONDRION: DECISIVE FOR CELL DEATH CONTROL? (1999) (0)
- EDITORIALS Arsenic Trioxide, a Novel Mitochondriotoxic Anticancer Agent? (1999) (0)
- Lysosomotropic agents including azithromycin, chloroquine and hydroxychloroquine activate the integrated stress response (2021) (0)
- Death, danger, and immunity (2007) (0)
- Diacylglycerol triggers Rim101 pathway–dependent necrosis in yeast: a model for lipotoxicity (2018) (0)
- P118 The capacity of the hypomethylating agents azacytidine and decitabine to induce apoptosis and cell cycle arrest depends on the activation of the DNA-damage response pathway (2009) (0)
- Abstract IA15: Microbiota and cancer immunosurveillance: An introduction (2016) (0)
- Arsenic trioxide as an inducer of immunogenic cell death (2023) (0)
- ErratumNonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint (2012) (0)
- Impact of microbiota on breast cancer hormone therapy (2023) (0)
- Defective proteostasis in celiac disease as a new therapeutic target (2019) (0)
- Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia–ischemia (2018) (0)
- G-quadruplex ligands as potent regulators of lysosomes. (2023) (0)
- Autophagy is a tissue-specific regulator of homeostasis and survival (2014) (0)
- Exercise-induced sudden cardiac death is caused by mitochondrio-nuclear translocation of AIF (2021) (0)
- The autophagic network and cancer (2018) (0)
- Apoptosis-associeted mitochondrial alterations in steatosis (2012) (0)
- Editorial Board (2009) (0)
- [Mechanisms of immune homeostasis: implications for the pathogenesis of autoimmune diseases]. (1992) (0)
- NF- (cid:1) B constitutes a potential therapeutic target in high-risk myelodysplastic syndrome (2006) (0)
- Organelle-specific regulation of toxin-induced cell death (2007) (0)
- Abstract 5128: Induction of immunogenic cell death and tumor regression in murine animal models by a novel cytolytic compound, LTX-401 (2017) (0)
- The endoplasmic reticulum stress sensor IRE1 regulates collagen secretion through the enforcement of the proteostasis factor P4HB/PDIA1 contributing to liver damage and fibrosis (2023) (0)
- Ankyrine-Rich TRP Channel, ANKTM1, TRPA1 (2012) (0)
- Immunogenicity of Cytotoxic Drugs: Molecular Bases and Clinical Implementation (2007) (0)
- The EGFR-Inhibitor Erlotinib Induces Apoptosis in Neoplastic Cells of Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML), an Effect Determined by the Expression Level of Nucleophosmin (NPM). (2006) (0)
- Photodynamic therapy with redaporfin induces ER stress and immunogenic cell death (2017) (0)
- Abstract SY28-03: Targeting tetraploidy for cancer therapy by pharmacological and immunological strategies. (2013) (0)
- myelodysplastic syndrome B constitutes a potential therapeutic target in high-risk κ NF- (2011) (0)
- Calreticulin surface presentation can promote quality control of hematopoietic stem cells. (2022) (0)
- PP 4.3 – 00052 Intra- and extracellular levels of acyl-coA-binding protein and anti-HIV T-cell function in people living with HIV (2022) (0)
- Prognostic value of dendritic cells in locally advanced cervical cancer patients. (2020) (0)
- Ferroptosis in hepatocellular carcinoma: from bench to bedside. (2023) (0)
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- Linking cellular stress responses to systemic homeostasis (2018) (0)
- DBI/ACBP is a targetable autophagy checkpoint involved in aging and cardiovascular disease. (2022) (0)
- MOLECULAR AND FUNCTIONAL ALTERATIONS OF ORGANELLE CROSSTALK DURING CELLULAR STRESS AND TUMORIGENESIS (2009) (0)
- Quantification of cell cycle-arresting proteins. (2013) (0)
- Antibody–drug conjugates harboring a kinesin spindle protein inhibitor with immunostimulatory properties (2022) (0)
- Nanoparticles releasing immunogenic cell death inducers upon near-infrared light exposure (2022) (0)
- Prolonged SARS-CoV-2 RNA virus shedding and 1 lymphopenia are hallmarks of COVID-19 in cancer 2 patients with poor prognosis 3 4 (2021) (0)
- 369 Anticancer Immune Responses Induced by Chemotherapeutic Agents Depends on Autophagy (2012) (0)
- Autophagy, Inflammation, and Metabolism (AIM) Center in its second year (2019) (0)
- [Cancer cells and their environments: friends and foes]. (2014) (0)
- Crystal Structure of Apoptosis Inducing Factor (AIF) (2002) (0)
- Beneficial autoimmunity links primary biliary cholangitis to the avoidance of cholangiocarcinoma (2021) (0)
- Assessment of eIF2α phosphorylation during immunogenic cell death. (2022) (0)
- Interaction between the adenine nucleotide translocator and the human immunodeficiency virus-1 protein Vpr (2006) (0)
- Squaramide-based synthetic chloride transporters activate TFEB but block autophagic flux (2019) (0)
- Defective Immunity Against SARS-CoV-2 Omicron Variants Despite Full Vaccination in Hematologic Malignancies. (2023) (0)
- Science Magazine (2006) (0)
- Introduction to the Special Issue: Nutrition, microbiota and immunity. (2023) (0)
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- Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR (2018) (0)
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- Mitochondrial Membrane Permeabilization in Physiological and Pathological Cell Death (2001) (0)
- The EGFR-Inhibitor Erlotinib Induces Differentiation, Cell Cycle Arrest and Apoptosis in EGFR-Negative Cells of MDS and AML. (2007) (0)
- Diagnostic, Prognostic and Mechanistic Biomarkers of COVID-19 Identified by Mass Spectrometric Metabolomics (2023) (0)
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- Unchaining NK cell–mediated anticancer immunosurveillance (2016) (0)
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- Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice (2019) (0)
- Immune checkpoint inhibitors (2021) (0)
- [The 2000 years]. (2015) (0)
- Principles of Oncoimmunology (2018) (0)
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- Immune-checkpoint inhibitors (2020) (0)
- Metabolomic profiling of cultured cancer cells. (2014) (0)
- An unexpected link between immunogenic cell death and inhibition of gene transcription (2020) (0)
- The molecular machinery of regulated cell death (2019) (0)
- Novel galenic formulations for delivering immunochemotherapies: kill intelligently, remove the checkpoint and let the T cells in! (2020) (0)
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- Autophagy-mediated metabolic effects of aspirin (2020) (0)
- Abstract 706: Novel MPS1 inhibitors with potential anticancer activity. (2013) (0)
- Metabolic and psychiatric effects of acyl coenzyme A binding protein (ACBP)/diazepam binding inhibitor (DBI) (2020) (0)
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- AIF-regulated oxidative phosphorylation supports lung cancer development (2019) (0)
- Abstract 4309: Mode of action of LTX315-induced cell death (2017) (0)
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- P057 Abrogation of the DNA-damage response in AML versus MDS cell lines (2007) (0)
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- Therapy-induced microenvironmental changes in cancer (2016) (0)
- Human Peripheral T Lymphocytes Anti-CD 2 or Staurosporine in Activated Caspase-Independent Cell Death Induced by (1998) (0)
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- P068 Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome (2009) (0)
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- Erratum to Martins I, et al. Cell Cycle Volume 8, Issue 22; pp. 3723–8 (2012) (0)
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- in Cells Lacking Mitochondrial DNA Apoptosis-associated Derangement of Mitochondrial Function (2006) (0)
- Trial Watch (2013) (0)
- Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer (2019) (0)
- The endoplasmic reticulum chaperone BiP: a target for immunogenic cell death inducers? (2022) (0)
- Further Evidence That MDS and AML Cells Exhibit a Differential Capacity To Activate the DNA-Damage Response (DDR) Pathways. (2007) (0)
- Immunogenic Therapies Drive CAR T Cells towards Superior Efficacy. (2021) (0)
- Expression and Function of the P-Glycoprotein (P-gp) In Myelodysplastic Syndromes (MDS) Treated with Azacytidine (AZA) (2011) (0)
- Tailed giant Tupanvirus possesses the most complete translational apparatus of the known virosphere (2018) (0)
- Necrocide 1 mediates necrotic cell death and immunogenic response in human cancer cells (2023) (0)
- 8 Immunogenicity of Cell Death for Optimal Efficacy of Chemotherapy (2012) (0)
- In Vivo Imaging of Orthotopic Lung Cancer Models in Mice. (2021) (0)
- PDIA3 as a potential bridge between immunogenic cell death and autoreactivity (2022) (0)
- Luigi Maiuri: un Grande Uomo - a Great Spirit (2019) (0)
- Innate immunity. (2012) (0)
- Autoradiographic and immunocytochemical studies of perichromatin granules accumulated in the nuclei of heat‐shocked cells (1988) (0)
- Favoriser le bourgeonnement du virus de l’hépatite C (2007) (0)
- activity necrosis-like programmed cell death mediated by serine protease positive human leukemic cells: caspase-independent, - BCR-ABL induced cell death of - A novel mechanism for imatinib mesylate (2013) (0)
- Author Correction: Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis (2018) (0)
- 189 Hypomethylating agents induce apoptosis and cell cycle arrest with a concomitant activation of p53-dependent signalling pathways and Foxo3a activation (2011) (0)
- Use of the compound Ro5-4864 compounds and derivatives for the preparation of medicaments for the treatment of tumor pathologies (2000) (0)
- Erlotinib Increases Efficacy of 5-Azacitidine (AZA) by Inhibiting Drug Efflux Via ABC-Transporters (2010) (0)
- Modes of action of ipilimumab and biomarkers of resistance to therapy in patients (2013) (0)
- The polarity and specificity of SARS-CoV2 -specific T lymphocyte responses determine disease susceptibility (2021) (0)
- Abstract SY03-01: The desirable death of the cancer cell: Immunogenic cell death for optimal chemotherapy (2010) (0)
- Molecular and Cellular Oncology (2014) (0)
- Clonal deletion and anergy: from models to reality. Introduction. (1992) (0)
- Cytokines and their receptors (1991) (0)
- Cellular senescence and the host immune system in aging and age-related disorders. (2023) (0)
- Cloning and Sequencing of Murine Lupus-Associated Autoantibody Genes (1988) (0)
- A druggable copper-signalling pathway that drives inflammation (2023) (0)
- Serum Metabolome Adaptations Following 12 Weeks of High-Intensity Interval Training or Moderate-Intensity Continuous Training in Obese Older Adults (2023) (0)
- Identification of pharmacological inhibitors of conventional protein secretion (2018) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity (2020) (0)
- Cell Stress - a new journal for cellular pathophysiology (2017) (0)
- Erratum to: Flt3 receptor inhibition reduces constitutive NFκB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia (2015) (0)
- Preface: oncometabolism: a new field of research with profound therapeutic implications. (2014) (0)
- [Chromatin structure with no nucleosomes: dissociated SV40 virus]. (1981) (0)
- Antagonistic pleiotropy: the example of cardiac insulin-like growth factor signaling, which is essential in youth but detrimental in age (2023) (0)
- Anticancer effects of polyadenylic-polyuridylic acid (poly[A:U]) and uncoupling of chemokine receptor signaling: Role of CCR5 and CXCR3. (2009) (0)
- Reply to Gostner and Fuchs. (2019) (0)
- The adenine nucleotide translocator as a potential therapeutic target Review Article (2004) (0)
- ACTIVATEURS DE LA VOIE AUTOPHAGE (2010) (0)
- Chemosensitization strategies for the treatment of lung cancer (2015) (0)
- Enhancement of Radiation Response in p53-deficient Cancer Cells In vivo using Different Schedules of Radiation and AZD1152, an Aurora B Kinase Inhibitor (2008) (0)
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Other Resources About Guido Kroemer
What Schools Are Affiliated With Guido Kroemer?
Guido Kroemer is affiliated with the following schools:
- University of Geneva
- Karolinska Institute
- Sorbonne University
- University of Ferrara
- Autonomous University of Madrid
- University of Innsbruck
- University of Queensland
- Université Paris Cité
- University of Verona
- University of Technology of Compiègne
- Aix-Marseille University
- Kyoto University
- Paris Diderot University
- Burgundy - Franche-Comté University Group
- Paris-Saclay University
- University of Konstanz
