Harold L. Moses

Q: What Schools Are Affiliated With Harold L. Moses

Harold L. Moses is affiliated with the following schools: Massachusetts General Hospital, Berea College, New York University, University of Pennsylvania, University of the Cumberlands, University of Alabama, MD Anderson Cancer Center, Vanderbilt University, University of Chicago

Harold L. Moses's AcademicInfluence.com Rankings

Harold L. Moses

Law

#1234

World Rank

#1573

Historical Rank

Common Law

#18

World Rank

#20

Historical Rank

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Harold L. Moses's Degrees

Doctorate Medicine University of Pennsylvania

Why Is Harold L. Moses Influential?

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According to Wikipedia, Harold L. Moses is the Ingram Professor of Cancer Research, Professor of Cancer Biology, Medicine and Pathology, and director emeritus at the Vanderbilt-Ingram Cancer Center. He was president of the American Association for Cancer Research in 1991.

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Harold L. Moses's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Stromal fibroblasts in cancer initiation and progression (2004) (2251)
Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer (2006) (1298)
TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia (2004) (1245)
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. (2014) (1182)
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. (2001) (1038)
Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium (1988) (976)
TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights (1990) (947)
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. (2008) (915)
Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. (2015) (890)
TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression. (2010) (820)
Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection (2016) (816)
Production and auto-induction of transforming growth factor-α in human keratinocytes (1987) (815)
Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta (1987) (809)
Phosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor β-mediated Epithelial to Mesenchymal Transition and Cell Migration* (2000) (789)
Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor. (1984) (746)
Growth factors and cancer. (1986) (730)
Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin (1990) (723)
The roles of TGFβ in the tumour microenvironment (2013) (699)
Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development (1991) (665)
TGF-β1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains (1990) (633)
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium. (1986) (600)
Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription* (1999) (566)
The cell biology of transforming growth factor β (1990) (528)
Transforming growth factor production by chemically transformed cells. (1981) (523)
How many mutations are required for tumorigenesis? implications from human cancer data (1993) (507)
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. (2004) (505)
Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity. (1986) (499)
Expression of a Truncated, Kinase-Defective TGF-β Type II Receptor in Mouse Skeletal Tissue Promotes Terminal Chondrocyte Differentiation and Osteoarthritis (1997) (492)
Tumor-stroma interactions. (2005) (478)
Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self- regulating system (1990) (470)
Transforming growth factor beta 1-induced changes in cell migration, proliferation, and angiogenesis in the chicken chorioallantoic membrane (1990) (466)
A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance. (1990) (434)
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular-fibrosis and tumor progression (2016) (424)
Transforming growth factors and the regulation of cell proliferation. (1990) (413)
Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. (1987) (408)
Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells (1987) (399)
Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation. (1990) (399)
Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat. (1988) (397)
TGF- and cancer (2006) (383)
A tale of two proteins: Differential roles and regulation of Smad2 and Smad3 in TGF‐β signaling (2007) (363)
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. (2006) (358)
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects (2003) (351)
Transforming Growth Factor β and Cell Cycle Regulation (1995) (350)
Regulation of intestinal epithelial cell growth by transforming growth factor type beta. (1989) (340)
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta (1988) (338)
Integrin β1 Signaling Is Necessary for Transforming Growth Factor-β Activation of p38MAPK and Epithelial Plasticity* (2001) (338)
Effect of IGF‐I in the Chondrogenesis of Bone Marrow Mesenchymal Stem Cells in the Presence or Absence of TGF‐β Signaling (2005) (327)
Transforming growth factor beta (TGF-beta) and inflammation in cancer. (2010) (321)
Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. (2010) (319)
Serum contains a platelet-derived transforming growth factor. (1982) (314)
In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. (1990) (304)
Mammary tumor suppression by transforming growth factor beta 1 transgene expression. (1995) (299)
Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. (2007) (295)
Inhibition of DNA Synthesis in rat hepatocytes by Platelet-derived Type β Transforming Growth Factor (1986) (290)
Inhibition of mammary duct development but not alveolar outgrowth during pregnancy in transgenic mice expressing active TGF-beta 1. (1993) (281)
Presentations and outcomes of neurosarcoidosis: a study of 54 cases. (2009) (271)
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. (2005) (267)
Human Transforming Growth Factor- β3: Recombinant Expression, Purification, and Biological Activities in Comparison with Transforming Growth Factors-β 1 and -β2 (1989) (266)
Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks (2005) (264)
Active and latent forms of transforming growth factor beta activity in synovial effusions (1989) (253)
Production of transforming growth factors by human colon cancer lines. (1986) (241)
Growth modulation of mouse keratinocytes by transforming growth factors. (1988) (239)
Murine transforming growth factor-beta 2 cDNA sequence and expression in adult tissues and embryos. (1989) (235)
Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. (2011) (233)
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticity. (2001) (229)
Increased Malignancy of Neu-Induced Mammary Tumors Overexpressing Active Transforming Growth Factor β1 (2003) (224)
Ovarian thecal cells produce transforming growth factor-beta which can regulate granulosa cell growth. (1987) (220)
Regulation of mRNAs for type-1 plasminogen activator inhibitor, fibronectin, and type I procollagen by transforming growth factor-beta. Divergent responses in lung fibroblasts and carcinoma cells. (1988) (219)
Regulation of differentiation by TFG-β (1996) (210)
Transforming Growth Factor α and β Expression in Human Colon Cancer Lines: Implications for an Autocrine Model (1987) (210)
Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2 (1989) (205)
Transforming Growth Factor-β Signaling–Deficient Fibroblasts Enhance Hepatocyte Growth Factor Signaling in Mammary Carcinoma Cells to Promote Scattering and Invasion (2008) (205)
Induction by transforming growth factor-β1 of epithelial to mesenchymal transition is a rare event in vitro (2004) (203)
Adrenal Cholesterol: Localization by Electron-Microscope Autoradiography (1969) (201)
Specific binding to cultured cells of 125I-labeled type beta transforming growth factor from human platelets. (1984) (200)
Cloning of a Novel Type II Serine/Threonine Kinase Receptor through Interaction with the Type I Transforming Growth Factor-β Receptor (*) (1995) (199)
TGF-beta biology in mammary development and breast cancer. (2011) (197)
Expression of transforming growth factor beta 2 RNA during murine embryogenesis. (1989) (197)
Differential expression of genes encoding TGFs β1, β2, and β3 during murine palate formation (1990) (191)
Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension (2018) (190)
TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. (1990) (188)
Spatial and temporal patterns of immunoreactive transforming growth factor beta 1, beta 2, and beta 3 during excisional wound repair. (1993) (186)
TGF beta 1 inhibits branching morphogenesis and N-myc expression in lung bud organ cultures. (1994) (179)
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis (2018) (179)
Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion. (1987) (177)
Production and auto-induction of transforming growth factor-alpha in human keratinocytes. (1987) (177)
Transforming Growth Factor β Receptor Type II Inactivation Promotes the Establishment and Progression of Colon Cancer (2004) (176)
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. (2006) (176)
STRAP and Smad7 Synergize in the Inhibition of Transforming Growth Factor β Signaling (2000) (176)
Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells. (1988) (173)
Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis. (2007) (172)
Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval. (1985) (170)
LEAD ION AND PHOSPHATASE HISTOCHEMISTRY I. NONENZYMATIC HYDROLYSIS OF NUCLEOSIDE PHOSPHATES BY LEAD ION (1966) (169)
Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks. (2005) (165)
PITFALLS IN THE USE OF LEAD ION FOR HISTOCHEMICAL LOCALIZATION OF NUCLEOSIDE PHOSPHATASES (1968) (163)
Stromally derived lysyl oxidase promotes metastasis of transforming growth factor-β-deficient mouse mammary carcinomas. (2013) (162)
ULTRASTRUCTURAL STUDIES OF VASOPRESSIN EFFECT ON ISOLATED PERFUSED RENAL COLLECTING TUBULES OF THE RABBIT (1968) (159)
Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer (2018) (157)
Some characteristics of a Ca2+ dependent ATPase activity associated with a group of erythrocyte membrane proteins which form fibrils. (1970) (154)
Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. (2002) (153)
A National Cancer Clinical Trials System for the 21st Century: Reinvigorating the NCI Cooperative Group Program (2010) (153)
Transforming growth factor beta 1 can induce estrogen-independent tumorigenicity of human breast cancer cells in athymic mice. (1993) (152)
Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor beta 1. (1995) (151)
Mechanism of Activation of Latent Recombinant Transforming Growth Factor by Plasmin (1990) (150)
Conditional inactivation of the TGF‐β type II receptor using Cre:Lox (2002) (149)
TGF-β signaling is essential for joint morphogenesis (2007) (148)
Complementary DNA Cloning of the Murine Transforming Growth Factor-β3 (TGFβ3) Precursor and the Comparative Expression of TGFβ3 and TGFβ1 Messenger RNA in Murine Embryos and Adult Tissues (1989) (146)
Transforming growth factor beta gene expression and action in the seminiferous tubule: peritubular cell-Sertoli cell interactions. (1989) (146)
Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones. (2004) (145)
Regulation of Plasminogen Activator Inhibitor-1 Expression by Transforming Growth Factor-β-induced Physical and Functional Interactions between Smads and Sp1* (2000) (145)
Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching. (1999) (142)
Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer? (2008) (141)
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line (2003) (139)
Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer. (2015) (138)
The cell biology of transforming growth factor beta. (1990) (137)
LEAD ION AND PHOSPHATASE HISTOCHEMISTRY II. EFFECT OF ADENOSINE TRIPHOSPHATE HYDROLYSIS BY LEAD ION ON THE HISTOCHEMICAL LOCALIZATION OF ADENOSINE TRIPHOSPHATASE ACTIVITY (1966) (136)
Diagnostic and therapeutic aspects of Hashimoto's encephalopathy (2013) (136)
Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor formation. (2003) (136)
Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. (2008) (134)
Dominant-negative interference of the transforming growth factor beta type II receptor in mammary gland epithelium results in alveolar hyperplasia and differentiation in virgin mice. (1998) (133)
Transforming growth factors and control of neoplastic cell growth (1987) (132)
Identification of STRAP, a Novel WD Domain Protein in Transforming Growth Factor-β Signaling* (1998) (129)
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. (2009) (129)
The Discovery and Early Days of TGF-β: A Historical Perspective. (2016) (127)
Comparison of intra- and extracellular transforming growth factors from nontransformed and chemically transformed mouse embryo cells. (1983) (126)
A delicate balance: TGF‐β and the tumor microenvironment (2007) (125)
Growth stimulation of human breast cancer cells with anti-transforming growth factor beta antibodies: evidence for negative autocrine regulation by transforming growth factor beta. (1990) (125)
Biomarker Tests for Molecularly Targeted Therapies--The Key to Unlocking Precision Medicine. (2016) (123)
Expression of Transforming Growth Factor-β1, -β2, and -β3 mRNA and Protein in the Murine Lung (1991) (122)
Mouse embryos contain polypeptide growth factor(s) capable of inducing a reversible neoplastic phenotype in nontransformed cells in culture (1982) (120)
Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product. (1991) (119)
RhoB Is Stabilized by Transforming Growth Factor β and Antagonizes Transcriptional Activation* (1998) (117)
Transforming growth factor β regulation of cell proliferation (1987) (116)
TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. (2011) (116)
Rapamycin Potentiates Transforming Growth Factor β-Induced Growth Arrest in Nontransformed, Oncogene-Transformed, and Human Cancer Cells (2002) (114)
Regulation of the synthesis and activity of urokinase plasminogen activator in A549 human lung carcinoma cells by transforming growth factor-beta (1988) (114)
TGFβ1 and TGFβ2 are potential growth regulators for low‐grade and malignant gliomas in vitro: Evidence in support of an autocrine hypothesis (1991) (113)
TGF-β-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest (2003) (111)
Infliximab for the treatment of CNS sarcoidosis (2017) (110)
Transforming growth factors in solid human malignant neoplasms. (1983) (109)
Transforming growth factor beta and cell cycle regulation. (1995) (108)
The loss of TGF-beta signaling promotes prostate cancer metastasis. (2003) (104)
Interaction of the Transforming Growth Factor-β Type I Receptor with Farnesyl-protein Transferase-α (*) (1995) (103)
Biochemical and biological differences between E7 oncoproteins of the high- and low-risk human papillomavirus types are determined by amino-terminal sequences (1991) (101)
Proliferation of Estrogen Receptor-α-Positive Mammary Epithelial Cells Is Restrained by Transforming Growth Factor-β1 in Adult Mice (2005) (100)
Effect of cell proliferation on levels and diversity of poly(A)-containing mRNA (1976) (100)
Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules. (1990) (99)
Transforming growth factor type β regulation of actin mRNA (1986) (99)
Epithelial tissue-derived growth factor-like polypeptides. (1983) (97)
Regulation of differentiation by TGF-beta. (1996) (97)
Light and electron microscopic studies of pigment in human and rhesus monkey substantia nigra and locus coeruleus (1966) (96)
Role of TGF-β Signaling in Generation of CD39+CD73+ Myeloid Cells in Tumors (2014) (95)
Cell‐cell communication and growth control of normal and cancer cells: Evidence and hypothesis (1993) (94)
Mechanism of growth arrest of chemically transformed cells in culture. (1978) (93)
Tgfβ signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development (2006) (92)
The murine type II TGF-beta receptor has a coincident embryonic expression and binding preference for TGF-beta 1. (1994) (91)
Transforming growth factor beta 1 regulation of c-myc expression, pRB phosphorylation, and cell cycle progression in keratinocytes. (1992) (90)
Inhibition of BMP Signaling Suppresses Metastasis in Mammary Cancer (2014) (90)
Differential effects of epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serum-free cultures of AKR-2B cells. (1984) (88)
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators (2011) (88)
Salicylate-induced Growth Arrest Is Associated with Inhibition of p70s6k and Down-regulation of c-Myc, Cyclin D1, Cyclin A, and Proliferating Cell Nuclear Antigen* (2000) (87)
Characterizing absolute lymphocyte count profiles in dimethyl fumarate–treated patients with MS (2016) (87)
Infectious mononucleosis: detection of herpeslike virus and reticular aggregates of small cytoplasmic particles in continuous lymphoid cell lines derived from peripheral blood. (1968) (86)
Transforming Growth Factor‐β: A Family of Growth Regulatory Peptides (1990) (85)
Characterization of the Interaction of FKBP12 with the Transforming Growth Factor-β Type I Receptor in Vivo* (1996) (85)
Activin receptor-like kinase 2 and Smad6 regulate epithelial-mesenchymal transformation during cardiac valve formation. (2005) (83)
Signaling to the epithelium is not sufficient to mediate all of the effects of transforming growth factor β and bone morphogenetic protein 4 on murine embryonic lung development (2001) (83)
Phosphorylation-dependent Interaction of the Cytoplasmic Domains of the Type I and Type II Transforming Growth Factor- Receptors (*) (1995) (83)
Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension. (1990) (82)
Expression of and Response to Growth Regulatory Peptides by Two Human Pancreatic Carcinoma Cell Lines (1990) (82)
Fibroblast-Mediated Collagen Remodeling Within the Tumor Microenvironment Facilitates Progression of Thyroid Cancers Driven by BrafV600E and Pten Loss. (2016) (81)
Synergistic induction of cyclooxygenase-2 by transforming growth factor-beta1 and epidermal growth factor inhibits apoptosis in epithelial cells. (1999) (80)
Production of transforming growth factor-alpha by normal rat small intestine. (1991) (79)
Infectious Mononucleosis: Continuous Suspension Culture of Peripheral Blood Leucocytes (1968) (79)
Inactivation of the transforming growth factor β type II receptor in human small cell lung cancer cell lines (1999) (77)
Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2. (1989) (77)
A delicate balance: TGF-beta and the tumor microenvironment. (2007) (76)
Regulation of epithelial cell proliferation by transforming growth factors (1989) (74)
TGF-beta and cancer. (2006) (74)
ON THE SIGNIFICANCE OF LEAD-CATALYZED HYDROLYSIS OF NUCLEOSIDE PHOSPHATES IN HISTOCHEMICAL SYSTEMS (1967) (73)
Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis. (2006) (73)
TGF‐β regulation of epithelial cell proliferation (1992) (72)
Human carcinoid cell production of paracrine growth factors that can stimulate fibroblast and endothelial cell growth. (1991) (72)
Treatment with farnesyl-protein transferase inhibitor induces regression of mammary tumors in transforming growth factor (TGF) alpha and TGF alpha/neu transgenic mice by inhibition of mitogenic activity and induction of apoptosis. (1999) (71)
TGF-β receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung (2008) (69)
ALCAM/CD166 is a TGF-β-responsive marker and functional regulator of prostate cancer metastasis to bone. (2014) (68)
Gain or loss of TGF-β signaling in mammary carcinoma cells can promote metastasis (2009) (68)
Immunodetection and modulation of cellular growth with antibodies against native transforming growth factor-beta 1. (1987) (68)
Gene expression in chemically transformed mouse embryo cells: Selective enhancement of the expression of C type RNA tumor virus genes (1977) (67)
Contributions by members of the TGFbeta superfamily to lens development. (2004) (67)
α2‐Macroglobulin and the α2‐Macroglobulin Receptor/LRP A Growth Regulatory Axis a (1994) (67)
The beta-type transforming growth factor. Mediators of cell regulation in the lung. (1990) (67)
Transforming growth factor beta 1 inhibits mouse keratinocytes late in G1 independent of effects on gene transcription. (1995) (66)
Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts (2012) (66)
Inactivation of TGF-beta signaling in hepatocytes results in an increased proliferative response after partial hepatectomy. (2005) (66)
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk (2012) (65)
Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis. (2007) (65)
Stem cells in lung development, disease, and therapy. (1997) (63)
Deletion of TGF‐β signaling in myeloid cells enhances their anti‐tumorigenic properties (2012) (63)
PI3K Inhibition Reduces Mammary Tumor Growth and Facilitates Antitumor Immunity and Anti-PD1 Responses (2016) (61)
Inhibition of DNA synthesis in rat hepatocytes by platelet-derived type beta transforming growth factor. (1986) (60)
Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice. (2005) (59)
TGF-p Stimulation and Inhibition of Cell Proliferation: New Mechanistic Insights Minireview (1990) (59)
Evidence for transforming growth factor-beta expression in human leptomeningeal cells and transforming growth factor-beta-like activity in human cerebrospinal fluid. (1992) (59)
Photodynamic effect of hematoporphyrin derivative as a function of optical spectrum and incident energy density. (1981) (59)
Association of herpes-like virus infection with infectious mononucleosis. (1969) (55)
Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells (2007) (55)
Differential expression of genes encoding TGFs beta 1, beta 2, and beta 3 during murine palate formation. (1990) (55)
Blocking CXCLs–CXCR2 axis in tumor–stromal interactions contributes to survival in a mouse model of pancreatic ductal adenocarcinoma through reduced cell invasion/migration and a shift of immune-inflammatory microenvironment (2019) (54)
Design, rationale, and baseline characteristics of the randomized double-blind phase II clinical trial of ibudilast in progressive multiple sclerosis. (2016) (54)
Nuclear RNA polymerase activities and poly(A)-containing mRNA accumulation in cultured AKR mouse embryo cells stimulated to proliferate. (1977) (53)
LEAD ION AND PHOSPHATASE HISTOCHEMISTRY III. THE EFFECTS OF LEAD AND ADENOSINE TRIPHOSPHATE CONCENTRATION ON THE INCORPORATION OF PHOSPHATE INTO FIXED TISSUE (1969) (53)
Inactivation of TGF-β signaling in hepatocytes results in an increased proliferative response after partial hepatectomy (2005) (53)
Inhibition of cell growth by TGF beta 1 is associated with inhibition of B-myb and cyclin A in both BALB/MK and Mv1Lu cells. (1994) (53)
Cancer Biomarkers: The Promises and Challenges of Improving Detection and Treatment (2007) (52)
The circulating lymphocyte--its role in infectious mononucleosis. (1968) (52)
Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer (2014) (51)
Farnesyltransferase Inhibitor Induces Rapid Growth Arrest and Blocks p70s6k Activation by Multiple Stimuli* (2000) (51)
Polyadenylylated RNA complementary to a mouse retrovirus-like multigene family is rapidly and specifically induced by epidermal growth factor stimulation of quiescent cells. (1982) (51)
Transforming growth factor beta regulation of cell proliferation. (1987) (50)
GFAP-Cre–Mediated Activation of Oncogenic K-ras Results in Expansion of the Subventricular Zone and Infiltrating Glioma (2009) (50)
Signal transduction by transforming growth factor‐β: A cooperative paradigm with extensive negative regulation (1998) (50)
Identification of novel Smad2 and Smad3 associated proteins in response to TGF‐β1 (2008) (49)
Regulation of epithelial proliferation by TGF-beta. (1991) (48)
TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. (2010) (48)
INTERPRETATION OF PHOSPHATASE CYTOCHEMICAL DATA (1970) (48)
TGF-β, Bone Morphogenetic Protein, and Activin Signaling and the Tumor Microenvironment. (2017) (48)
TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest. (2003) (48)
Does telomere shortening drive selection for p53 mutation in human cancer? (1995) (47)
Keratinocytes Produce and Are Regulated by Transforming Growth Factors (1988) (47)
Bone Morphogenetic Proteins Stimulate Mammary Fibroblasts to Promote Mammary Carcinoma Cell Invasion (2013) (47)
Modulation of transforming growth factor type beta action by activated ras and c-myc (1987) (47)
Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals. (2013) (46)
TGF‐β promotes cell death and suppresses lactation during the second stage of mammary involution (2009) (46)
p120-catenin is essential for terminal end bud function and mammary morphogenesis (2012) (45)
Telomeric associations and consistent growth factor overexpression detected in giant cell tumor of bone. (1991) (44)
pRb is necessary for inhibition of N-myc expression by TGF-beta 1 in embryonic lung organ cultures. (1995) (44)
Transforming growth factor-beta and transforming growth factor beta-receptor expression in human meningioma cells. (1992) (44)
Specific methods for the isolation of nuclei from chick oviduct. (1974) (43)
Visualization of nonfunctioning adrenal adenomas with iodocholesterol: possible relationship to subcellular distribution of tracer. (1978) (43)
Age- and Pregnancy-Associated DNA Methylation Changes in Mammary Epithelial Cells (2015) (42)
THE PARTICIPATION OF NUCLEOTIDE IN THE FORMATION OF PHOSPHATASE REACTION PRODUCT: A CHEMICAL AND ELECTRON MICROSCOPE AUTORADIOGRAPHIC STUDY (1969) (42)
ELECTRON MICROSCOPY OF THE TRIGEMINAL GANGLION. 3. TRIGEMINAL NEURALGIA. (1965) (42)
Benzo(A)pyrene metabolism and blast transformation in peripheral blood mononuclear cells from smoking and nonsmoking populations and lung cancer patients (1978) (42)
Expression of transforming growth factor-beta 1, -beta 2, and -beta 3 mRNA and protein in the murine lung. (1991) (41)
Inhibition of DNA Synthesis by a Farnesyltransferase Inhibitor Involves Inhibition of the p70s6k Pathway* (1999) (41)
Inhibition of TGF-β with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. (2017) (40)
Therapeutic effect of c‐Jun N‐terminal kinase inhibition on pancreatic cancer (2013) (40)
Inflammatory bowel disease-associated colorectal cancer: proctocolectomy and mucosectomy do not necessarily eliminate pouch-related cancer incidences (2011) (40)
Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial (2020) (40)
Purification and characterization of a novel transforming growth factor. (1987) (39)
Clinical outcomes in patients with relapsing-remitting multiple sclerosis who switch from natalizumab to delayed-release dimethyl fumarate: A multicenter retrospective observational study (STRATEGY). (2018) (39)
Cladribine tablets added to IFN-β in active relapsing MS (2018) (39)
Deletion of the BMP receptor BMPR1a impairs mammary tumor formation and metastasis (2015) (38)
Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression (2011) (38)
Transforming Growth Factor β in the Control of Epidermal Proliferation (1988) (38)
Signaling Pathways Regulating TC21-induced Tumorigenesis* (2007) (37)
Growth inhibitory polypeptides in the regulation of cell proliferation. (1987) (37)
Growth arrest of AKR‐2B cells maintained in the presence of epidermal growth factor or 12‐O‐tetradecanolyhorbol‐13 acetate: Evidence for two separate G1 arrest points (1980) (36)
Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells (2017) (36)
Antagonistic effects of TGFbeta1 and BMP-6 on skin keratinocyte differentiation. (2001) (35)
Quantitative analysis of the secretome of TGF‐β signaling‐deficient mammary fibroblasts (2010) (35)
Tumor suppressor genes in the TGF–β signaling pathway? (1996) (34)
Is colony‐stimulating factor‐1 a key mediator of breast cancer invasion and metastasis? (1993) (34)
COMPARISON AND CHARACTERIZATION OF NUCLEAR ISOLATION PROCEDURES AS APPLIED TO CHICK OVIDUCT (1973) (34)
Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model. (1987) (34)
Differential Binding of Transforming Growth Factor-β1, -β2, and -β3 by Fibroblasts and Epithelial Cells Measured by Affinity Cross-Linking of Cell Surface Receptors (1991) (33)
Mechanisms of transforming growth factor-beta 1-induced cell cycle arrest. (1994) (32)
Transforming growth factor-β in neural embryogenesis and neoplasia (1993) (32)
The spectrum of Susac’s syndrome (2009) (31)
Small molecule inhibitor of the bone morphogenetic protein pathway DMH1 reduces ovarian cancer cell growth. (2015) (31)
Inhibiting Cxcr 2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma (2011) (30)
Complementary DNA cloning of the murine transforming growth factor-beta 3 (TGF beta 3) precursor and the comparative expression of TGF beta 3 and TGF beta 1 messenger RNA in murine embryos and adult tissues. (1989) (30)
The concept of mRNA abundance classes: a critical reevaluation. (1978) (30)
Comparative fine structure of the trigeminal ganglia, including human autopsy studies. (1967) (30)
β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors. (2011) (30)
TGF beta regulation of epithelial cell proliferation: role of tumor suppressor genes. (1991) (29)
Binding of polycyclic aromatic hydrocarbons to transcriptionally active nuclear subfractions of AKR mouse embryo cells. (1976) (29)
Variation of microsomal mixed function oxidase(s) and human lung cancer (1980) (29)
Decreased epidermal growth factor binding in cells growth arrested in G1 by nutrient deficiency (1981) (29)
Growth factors, tumor promoters and cancer genes (1988) (28)
THE INFLUENCE OF POSTNATAL DEVELOPMENT ON DRUG-INDUCED HEPATIC PORPHYRIA AND THE SYNTHESIS OF CYTOCHROME P-450 (1971) (28)
Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis (2014) (28)
Small, virus-like particles detected in bovine sera by electron microscopy. (1974) (28)
TGF beta regulation of cell proliferation. (1994) (28)
BMPR2 loss in fibroblasts promotes mammary carcinoma metastasis via increased inflammation (2015) (27)
Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling. (2001) (26)
ELECTRON MICROSCOPY OF THE TRIGEMINAL GANGLION. II. AUTOPSY STUDY OF HUMAN GANGLIA. (1965) (26)
TGF-b and cancer (2006) (25)
Transforming growth factor beta mimetics: discovery of 7-[4-(4-cyanophenyl)phenoxy]-heptanohydroxamic acid, a biaryl hydroxamate inhibitor of histone deacetylase. (2002) (25)
Inhibition of DNA synthesis by a farnesyltransferase inhibitor involves inhibition of the p70(s6k) pathway. (1999) (25)
Electron microscopy of zosteriform herpes simplex infection in the mouse. (1972) (25)
Abstract 4383: Targeting tumor microenvironment with gemcitabine is useful for the treatment of pancreatic ductal adenocarcinoma (2012) (25)
Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma. (2016) (24)
Usage of primary cells to delineate IFN-gamma-responsive DNA elements in the HLA-DRA promoter and to identify a novel IFN-gamma-enhanced nuclear factor. (1992) (24)
Tumor necrosis factor alpha response elements in the HLA-DRA promoter: identification of a tumor necrosis factor alpha-induced DNA-protein complex in astrocytes. (1992) (24)
Transforming growth factors in the regulation of malignant cell growth and invasion. (1988) (23)
The impact of bone morphogenetic protein 4 (BMP4) on breast cancer metastasis in a mouse xenograft model. (2016) (23)
c-myc and pRB: Role in TGF-β1 Inhibition of Keratinocyte Proliferation (1991) (22)
Pathway Analyses Identify TGFBR2 as Potential Breast Cancer Susceptibility Gene: Results from a Consortium Study among Asians (2012) (22)
Age of meningitis or encephalitis is independently predictive of outcome from anterior temporal lobectomy (2002) (22)
Kips off to Myc: Implications for TGFβ signaling (1997) (21)
Blocking VCAM-1 inhibits pancreatic tumour progression and cancer-associated thrombosis/thromboembolism (2020) (21)
The beta-type transforming growth factor (1990) (21)
Cell cycle variation in 125I-labeled epidermal growth factor binding in chemically transformed cells. (1982) (21)
Cell Growth & Differentiation (1992) (21)
Growth factors, growth factor receptors, and cell cycle control mechanisms in chemically transformed cells. (1982) (21)
Analysis of transforming growth factor β receptor expression and signaling in higher grade meningiomas (2011) (21)
Growth stimulation, altered regulation of epidermal growth factor receptors, and autocrine transformation of spontaneously transformed normal rat kidney cells by transforming growth factor beta. (1989) (21)
Signal transduction by transforming growth factor-beta: a cooperative paradigm with extensive negative regulation. (1998) (21)
Biomarker Tests for Molecularly Targeted Therapies (2016) (20)
Under Pressure: Stromal Fibroblasts Change Their Ways (2005) (20)
TGF beta 1 and TGF beta 2 are potential growth regulators for low-grade and malignant gliomas in vitro: evidence in support of an autocrine hypothesis. (1991) (19)
Managing adverse effects of disease-modifying agents used for treatment of multiple sclerosis. (2008) (19)
Signaling cross-talk between IGF-binding protein-3 and transforming growth factor-(beta) in mesenchymal chondroprogenitor cell growth. (2005) (19)
Functional KRAS mutations and a potential role for PI3K/AKT activation in Wilms tumors (2017) (18)
Myeloid Cell–Derived TGFβ Signaling Regulates ECM Deposition in Mammary Carcinoma via Adenosine-Dependent Mechanisms (2020) (18)
Managing adverse effects of disease-modifying agents used for treatment of multiple sclerosis (2008) (18)
Alpha 2-macroglobulin and the alpha 2-macroglobulin receptor/LRP. A growth regulatory axis. (1994) (18)
Keratin 19 gene drives Cre recombinase expression throughout the early postimplantation mouse embryo (2005) (17)
Fine structure of leukocytes in infectious mononucleosis: in vivo and in vitro studies. (1969) (17)
Light and dark cells as artifacts of liver fixation. (1968) (17)
Transforming growth factor-beta (TGF-beta) and TGF-beta-associated kinase 1 are required for R-Ras-mediated transformation of mammary epithelial cells. (2008) (17)
E2F-independent transcriptional repression by p107, a member of the retinoblastoma family of proteins. (1995) (17)
Effects of BRCA1 Transgene Expression on Murine Mammary Gland Development and Mutagen-Induced Mammary Neoplasia (2007) (17)
TGFβ Signaling in Myeloid Cells Regulates Mammary Carcinoma Cell Invasion through Fibroblast Interactions (2015) (17)
Biomarker Tests for Molecularly Targeted Therapies: Laying the Foundation and Fulfilling the Dream. (2016) (17)
Gene therapy for the treatment of metastatic breast cancer by in vivo transduction with breast-targeted retroviral vector expressing antisense c-fos RNA. (1996) (17)
Transforming Growth Factor-β (1986) (16)
ELECTRON MICROSCOPY OF THE TRIGEMINAL GANGLION. I. COMPARATIVE ULTRASTRUCTURE. (1965) (16)
Phenotypic alterations in fibroblasts and fibrosarcoma cells that overexpress latent transforming growth factor-beta 1. (1992) (15)
Microdialysis Combined with Proteomics for Protein Identification in Breast Tumor Microenvironment In Vivo (2011) (15)
α‐Amanitin and 5‐fluorouridine inhibition of serumstimulated DNA synthesis in quiescent AKR‐2B mouse embryo cells (1979) (15)
Transforming growth factor-beta. A family of growth regulatory peptides. (1990) (15)
Aryl hydrocarbon hydroxylase in man and lung cancer. (1978) (14)
The Cell Membrane and Cell Signals as Targets in Cancer Chemotherapy AACR, EORTC, and BACR Special Conference in Cancer Research (1990) (14)
Pilot study to examine the effect of antibiotic therapy on MRI outcomes in RRMS (2005) (14)
TRAIL and interferon-alpha act synergistically to induce renal cell carcinoma apoptosis. (2010) (14)
Prostate cancer cells lose their sensitivity to TGFβI growth inhibition with tumor progression. (1995) (14)
Soluble VCAM-1 promotes gemcitabine resistance via macrophage infiltration and predicts therapeutic response in pancreatic cancer (2020) (14)
An infectious basis for multiple sclerosis: perspectives on the role of Chlamydia pneumoniae and other agents. (2001) (14)
Transforming Growth Factor β Platelet-derived Type Inhibition of DNA Synthesis in rat hepatocytes by Updated (2006) (14)
Concerted loss of TGFβ-mediated proliferation control and E-cadherin disrupts epithelial homeostasis and causes oral squamous cell carcinoma. (2014) (13)
Comparison of RNA metabolism in G1-arrested and stimulated nontransformed and chemically transformed mouse embryo cells in culture. (1979) (13)
Renal gold inclusions. A light and electron microscopic study. (1966) (13)
Synthesis of Transforming Growth Factor-/ 3 l by Megakaryocytes and Its Localization to Megakaryocyte and Platelet a-Granules (2003) (13)
Transforming growth factor regulation of keratinocyte growth. (1993) (13)
A Murine Model of K-RAS and β-Catenin Induced Renal Tumors Expresses High Levels of E2F1 and Resembles Human Wilms Tumor. (2015) (13)
Transforming growth factor-beta in neural embryogenesis and neoplasia. (1993) (13)
Isolation and characterization of kirsten murine sarcoma virus‐transformed mouse keratinocytes resistant to transforming growth factor beta (1990) (12)
Murine leukaemia C-type virus associated with functional murine carcinomas of endocrine origin. (1971) (12)
A structural analysis of hepatomegaly induced by a hormone-secreting tumor. (1967) (12)
c‐Myc‐enhanced S phase entry in keratinocytes is associated with positive and negative effects on cyclin‐dependent kinases (1998) (12)
COMMITTEE ON CANCER CLINICAL TRIALS AND THE NCI COOPERATIVE GROUP PROGRAM (2010) (12)
Occult celiac disease presenting as epilepsy and MRI changes that responded to gluten-free diet (2007) (12)
Differential binding of transforming growth factor-beta 1, -beta 2, and -beta 3 by fibroblasts and epithelial cells measured by affinity cross-linking of cell surface receptors. (1991) (11)
Turn off the IDO: will clinical trials be successful? (2012) (11)
Efficacy of Cladribine Tablets as Add-On to IFN-beta Therapy in Patients with Active Relapsing MS: Final Results from the Phase II ONWARD Study (P3.029) (2016) (11)
Separation and characterization of transcriptionally active and inactive nuclear subfractions of AKR mouse embryo cells. (1976) (11)
Equivalent expression of endogenous murine leukemia virus-related genes in C3H/10T1/2 cells and chemically transformed derivative cells. (1978) (11)
Transforming growth factor type beta can act as a potent competence factor for AKR-2B cells. (1987) (10)
Genomic and proteomic analysis of mammary tumors arising in transgenic mice. (2005) (10)
The correlation of plasma membrane microvilli and intracellular cyclic AMP content in a rat epitheloid kidney cell line. (1976) (10)
Altered regulation of protein disulfide isomerase in cells resistant to the growth-inhibitory effects of transforming growth factor beta 1. (1990) (10)
Transforming growth factor beta in the control of epidermal proliferation. (1988) (10)
Molecular insights into altered cell cycle regulation and genitourinary malignancy. (1995) (9)
Frequency differences between nuclear and polysomal sequences of poly(A)‐containing RNA from cultured akr mouse embryo cells (1979) (9)
Herpetic (Inclusion-Body) Encephalitis (1965) (9)
Phosphatidylinositol-3 Kinase Function is Required for TGF β -mediated Epithelial to Mesenchymal Transition and Cell Migration (2000) (9)
Macromolecular binding of 3H-benzo(a)pyrene metabolites and lymphocyte transformation in patients with lung cancer, and in smoking and nonsmoking control subjects. (1979) (9)
Tumour stroma interactions (2010) (9)
Transforming growth factor type beta regulation of actin mRNA. (1986) (9)
Growth factors in the tumorigenicity of a brain tumor cell line. (1989) (9)
Covalent binding of benzo[a]pyrene metabolites to DNA, RNA and chromatin proteins in the AKR mouse embryo cell-line. (1981) (8)
Spatial and Temporal Patterns of Immunoreactive Transforming Growth Factor f31, 132, and f33 during Excisional Wound Repair (2007) (8)
TβRIII Expression in Human Breast Cancer Stroma and the Role of Soluble TβRIII in Breast Cancer Associated Fibroblasts (2016) (8)
Transforming growth factor type β in normal human urine (1987) (8)
The binding of benzo(a)pyrene and N‐methyl‐N′‐nitro‐n‐nitrosoguanidine to subnuclear fractions of akr mouse embryo cells in culture (1977) (8)
Tumor suppressor genes in the TGF-beta signaling pathway? (1996) (8)
Pharmacologic Inhibition of β-Catenin With Pyrvinium Inhibits Murine and Human Models of Wilms Tumor (2017) (8)
Effects of metabolism on the binding of polycyclic hydrocarbons to nuclear subfractions of cultured AKR mouse embryo cells. (1977) (7)
Circulating tumor cells in murine myeloma. (1977) (7)
c-myc and pRB: role in TGF-beta 1 inhibition of keratinocyte proliferation. (1991) (7)
TGF-beta1 regulates the expression of multiple max-interacting transcription factors in Balb/MK cells: implications for understanding the mechanism of action of TGF-beta1. (2001) (7)
Proliferation of Estrogen Receptor alpha Positive Mammary Epithelial Cells is Restrained by TGFbeta1 in Adult Mice (2005) (7)
TGF- b Biology in Mammary Development and Breast Cancer (2010) (7)
Competitive binding and metabolism of several carcinogenic polycyclic aromatic hydrocarbons by AKR mouse embryo cells in culture. (1978) (7)
Kips off to Myc: implications for TGF beta signaling. (1997) (7)
Identification of an interferon-γ-responsive element of a class II major histocompatibility gene in rat type 1 astrocytes (1991) (6)
The frequency and significance of human herpetic esophagitis. An autopsy study. (1963) (6)
Biological effects of transforming growth factors (1989) (6)
TGF-β1 Regulates the Expression of Multiple Max-Interacting Transcription Factors in Balb/MK Cells: Implications for Understanding the Mechanism of Action of TGF-β1 (2001) (6)
Real-World Clinical Outcomes in Relapsing-Remitting Multiple Sclerosis Patients who Switch from Natalizumab to Delayed-Release Dimethyl Fumarate: A Multicenter, Retrospective, Observational Study (STRATEGY) (P3.293) (2015) (6)
Hepatocellular changes associated with allylisopropylacetamide-induced hepatic porphyria in rats. (1970) (5)
1 The Discovery of TGF-β: A Historical Perspective (2008) (5)
UICC Study Group on basic and clinical cancer research: mechanisms of growth factor and hormone insensitivity (1997) (5)
Theophylline suppression of delta-aminolevulinic acid synthetase induction in chick embryo and rat livers. (1973) (5)
Efficacy and Tolerability of Fingolimod, Dimethylfumarate, and Teriflunomide in Patients with Multiple Sclerosis: Real World Experience from a Single Center (P6.168) (2016) (5)
Mechanism of syncytium formation between XC sarcoma cells and murine endocrine carcinoma cells. (1972) (5)
TGF-β in mammary development and neoplasia (1996) (4)
TGF-β helps cells fly solo (2009) (4)
Inhibition of transforming growth factor-β signaling in myeloid cells ameliorates aortic aneurysmal formation in Marfan syndrome (2020) (4)
The relationship of the fowl pox inclusion to viral replication. An electron microscopic study. (1963) (4)
Farnesyltransferase Inhibitor‐Induced Regression of Mammary Tumors in TGFα and TGFα/neu Transgenic Mice Correlates with Inhibition of Map Kinase and p70s6 Kinase Phosphorylation (1999) (4)
COMMITTEE ON POLICY ISSUES IN THE CLINICAL DEVELOPMENT AND USE OF BIOMARKERS FOR MOLECULARLY TARGETED THERAPIES (2016) (4)
Challenges and Opportunities to Updating Prescribing Information for Longstanding Oncology Drugs. (2019) (4)
Inhibition of DNA Synthesis by a Farnesyltransferase Inhibitor Involves Inhibition of the p 70 s 6 k Pathway * (1999) (4)
147 Aggressive Pancreatic Ductal Adenocarcinoma in Mice Releases Secreted Factors Into the Tumor Microenvironment to Enhance Tumor Progression (2008) (3)
Aryl hydrocarbon hydroxylase activity in subpopulations of peripheral blood mononuclear cells. (1978) (3)
Porphyria-inducing drugs: comparative effects on nuclear ribonucleic acid polymerases in rat liver. (1976) (3)
Expression of transforming growth factor pi RNA during murine embryogenesis (2005) (3)
UICC study group on basic and clinical cancer research (1997) (3)
Meharry Medical College–Vanderbilt–Ingram Cancer Center Partnership: Its History and Role in Cancer Health Disparities Research (2010) (3)
Oral Cladribine as Add on to IFN β Therapy in Patients with Active Multiple Sclerosis: Results from the Phase II ONWARD Study (P07.099) (2013) (2)
Expansion of Myeloid Immune Suppressor Cells in Tumor-bearing Host Directly Promotes Tumor Angiogenesis, Tumor Growth, and Metastasis (2007) (2)
The interaction and effects of chemical carcinogens on rat organ chromatin (1974) (2)
Myeloid Suppressor Cells Regulate the Lung Environment—Response (2011) (2)
Complexity and abundance of murine leukemia virus-related nuclear and messenger RNA sequences in mouse embryo cell lines which are differentially sensitive to carcinogen-induced virus activation. (1979) (2)
alpha-Amanitin and 5-fluorouridine inhibition of serum-stimulated DNA synthesis in quiescent AKR-2B mouse embryo cells. (1979) (2)
TGF-beta in mammary development and neoplasia. (1996) (2)
Regulation of Fibroblastic and Epithelial Cell Function by Transforming Growth Factors (1990) (2)
Fibroblasts Promotes Mammary Tumorigenesis Receptor Knockout β Transforming Growth Factor-Enhanced Hepatocyte Growth Factor Signaling by Type II (2007) (2)
Translocator protein (TSPO) as a molecular imaging biomarker of pancreatic cancer (2013) (2)
Transforming Growth Factor-i Increases Steady State Levels of Type I Procollagen and Fibronectin Messenger RNAs Posttranscriptionally in Cultured Human Dermal Fibroblasts (2013) (2)
Abstract 4083: Deletion of the BMP receptor BMPR1a results in EMT and impairs mammary gland tumor formation and metastasis (2015) (2)
Microenvironment Carcinoma Cell Survival and Interaction with the Adjacent Regulates Mammary β − Transforming Growth Factor (2008) (2)
9 – Control of Cell Proliferation by Transforming Growth Factors (1991) (2)
Binding of [3H]benzo(a)pyrene metabolites to the AKR mouse embryo cell line nuclear proteins. (1981) (2)
Specific binding to cultured cells of " 25 I-labeled type j 3 transforming growth factor from human platelets ( radioreceptor assay / soft agar growth / autocrine ) (2)
Fetal bovine serum contains polypeptides which stimulate colony formation by nontransformed cells. Abstr. (1982) (1)
Immunohistochemical Localization ofTGF#1, TGF02, and TGF03 in the Mouse Embryo : Expression Patterns Suggest Multiple Roles during Embryonic Development (2002) (1)
TGF-β Signaling in Fibroblasts Regulates Tumor Initiation and Progression in Adjacent Epithelia (2011) (1)
Efficacy of oral Multiple Sclerosis therapies in patients switching from natalizumab (P3.290) (2015) (1)
Abstract 2381: Preclinical molecular targeting therapy of pancreatic cancer using a genetically engineered mouse model (2011) (1)
Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk (2012) (1)
Abstract LB-495: Myeloid-derived suppressor cells promote cancer-associated fibroblast migration and carcinoma cell invasion (2012) (1)
Characterization of a binding protein which is specific, saturable and of high affinity for the carcinogen, benzo(a)pyrene (1981) (1)
Perspectives in Cancer Research Growth Factors and Cancer 1 (2006) (1)
Abstract 1714A: TGF-beta signaling on myeloid cells regulates ECM deposition in mammary carcinoma via adenosine dependent mechanisms (2020) (1)
Transforming Growth Factor-β and Cancer (2007) (1)
Abstract A69: The novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment. (2013) (1)
Transforming Growth Factor- B (TGF- B ) and TGF- B –Associated Kinase 1 Are Required for R-Ras–Mediated Transformation of Mammary Epithelial Cells (2008) (1)
The Meharry-Vanderbilt-Tennessee State University Cancer Partnership (MVTCP): History and Highlights of 20 Years of Accomplishments (2022) (1)
Treatment of Multiple Sclerosis - Relationship between Vitamin D and Interferon β-1b (2015) (1)
Abstract 2676: Inhibition of bmp signaling suppresses metastasis in mammary cancer (2014) (1)
Abstract LB-428: Upregulation of serum amyloid A1 (SAA 1) gene is associated with ulcerative colitis-related colon cancer (2011) (1)
Supporting Data Infrastructure for Biomarker Tests for Molecularly Targeted Therapies (2016) (1)
30 TGF-β and the Tumor Microenvironment (2008) (1)
Farnesyltransferase inhibitor-induced regression of mammary tumors in TGF alpha and TGF alpha/neu transgenic mice correlates with inhibition of map kinase and p70s6 kinase phosphorylation. (1999) (1)
Growth Factors and Cancer 1 (2006) (1)
Physician and Patient Participation in Cancer Clinical Trials (2010) (1)
615 TGF-beta regulation of the inflammatory tumour microenvironment (2010) (1)
Abstract 1500: Bone morphogenetic proteins stimulate mammary fibroblasts to promote mammary tumorigenesis (2012) (1)
Abstract IA15: Functional diversity of the pancreas tumor stroma (2016) (0)
Abstract A39: The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment with multi-kinase inhibitors (2012) (0)
Uncovering the Role of TGFβ and BMP in Triple Negative Breast Cancer Stem Cells (2013) (0)
The Characterization of Tumor Microenvironment in Tumors With and Without the TGF-β Signaling (0)
Abstract P6-03-04: TGF-β receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer (2015) (0)
Cancer microenvironments : Extended abstracts for the 37th International Symposium of the Princess Takamatsu Cancer Research Fund : November 14-16, 2006 Tokyo, Japan (2007) (0)
Frequency difference between nuclear and polysomal sequences of poly(A)-containing RNA from cultured AKR mouse embryo cells. (1979) (0)
Purification and Characterization of a Novel Transforming Growth Factor1 (2006) (0)
Complexityand Abundanceof MurineLeukemiaVirus-relatedNuclearand MessengerRNASequencesin MouseEmbryoCell LinesWhichAre DifferentiallySensitiveto Carcinogen-inducedVirusActivation ' (2006) (0)
Genotype tunes PDAC tension to drive matricellular-enriched fibrosis and tumor aggression (2016) (0)
Sample size calculation based on exact test for differential expression analysis of RNA-seq data (2014) (0)
Abstract LB-463: Proteomic patterns of colonic submucosa delineates the inflammatory colitides. This could aid understand IBD-related colorectal malignancy (2011) (0)
Abstract P3-05-09: The role of TGF-beta receptor type 3 in breast cancer progression (2012) (0)
Peripheral Blood Mononuclear Cells Aryl Hydrocarbon Hydroxylase Activity in Subpopulations of Updated (2006) (0)
Abstract 2058: Colorectal cancer in the setting of inflammatory bowel disease: role of hemoglobin (2012) (0)
The Science of Developing Cancer Therapy (2010) (0)
Previous and Ongoing Analyses Undertaken by NCI (2010) (0)
Cancer Metastasis: Introduction to Basic Research (2011) (0)
Abstract B71: Potential role of hemoglobin in colorectal cancer initiation in inflammatory bowel disease setting. (2012) (0)
Abstract B10: Epidermal growth factor receptor inhibitor prolongs survival in pancreatic cancer by blocking gemcitabine-induced mitogen-activated protein kinase signal (2014) (0)
Abstract LB-450: Gene expression of colonic submucosa differs between the inflammatory colitides. A possible reason for differences in IBD-associated CRC incidences (2011) (0)
Purification and Characterization of a Novel Transforming Growth Factor 1 (2006) (0)
Transforming Growth Factor a and 0 Expression in Human Colon Cancer Lines: Implications for an Autocrine Model1 (2006) (0)
Abstract B27: Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced mitogen-activated protein kinase signal. (2012) (0)
Transforming growth factor beta receptor type III is a tumor promoter in mesenchymal-stem like triple negative breast cancer (2014) (0)
Dr. Harold (Hal) Moses on TGF-beta Regulation of Stromal-Epithelial Interactions in Cancer (2007) (0)
Use of a Pulsed-Flow Lavage Unit for Bronchial Washing (1974) (0)
Transforming growth factor-β: A major regulator of cell growth and proteolytic activity (1987) (0)
Envisioning a Rapid Learning System for Biomarker Tests for Molecularly Targeted Therapies (2016) (0)
Growth factors, tumor promoters and cancer genes : proceedings of a Triton Biosciences-UCLA Symposium held in Steamboat Springs, Colorado, April 6-13, 1986 (1988) (0)
[Growth inhibitory and cytotoxic polypeptides ; proceedings of a Genentech-Smith, Kline & French-Triton Biosciences-UCLA Symposium held in Keystone, Colorado, January 24-30, 1988 (1989) (0)
Abstract 544: Blockade of CXC chemokines/CXCR2 axis in the tumor microenvironment as a potent therapeutic strategy for pancreatic ductal adenocarcinoma (2011) (0)
Intestinal Tumorigenesis and Wnt Pathways in Mammary and β Growth Factor-Transcriptional Cooperation between the Transforming (2006) (0)
Transformation of Mammary Epithelial Cells Mediated − Associated Kinase 1 Are Required for R-Ras − β ) and TGF-β ( TGF-β Transforming Growth Factor-Updated (2008) (0)
413: The Conditional Knock-Out of Transforming Growth Factor-Beta Signaling in the Prostate Stroma Results in Prostate Intraepithelial Neoplasia (2004) (0)
Epidermal growth factor receptors in chemically transformed and nontransformed cells in culture. Abstr. (1979) (0)
Abstract A56: Bone morphogenetic protein antagonist DMH1 inhibits metastasis in a mouse model of breast cancer (2013) (0)
Abstract 4698: Gene expression profiles of triple negative breast cancer epithelial and stromal cells are predictive of treatment response. (2013) (0)
Information-Gathering Sessions and Speakers (2016) (0)
Regulator of Prostate Cancer Metastasis to Bone Responsive Marker and Functional − β ALCAM / CD 166 Is a TGF (2014) (0)
Transforming growth factor-β (TGF-β) is a group of multi- functional regulatory polypeptides that are secreted by a large variety of cells and play a crucial role in cell proliferation, differentiation, migration and extracellular matrix production (1993) (0)
Transforming growth factor type beta in normal human urine. (1987) (0)
Mouse Models of Brain Cancer: Insight into the Cytopathogenesis of Glioma (2011) (0)
TGF-beta regulation of the tumor microenvironment (2008) (0)
Nuclear chromatin fractions from mouse embryo cells: characterization and site specific binding of a chemical carcinogen (1975) (0)
Altered Prostate EpithelialDevelopment in Mice Lacking (2011) (0)
Transforming growth factor production by nontransformed and chemically transformed akr cells. Abstr. (1982) (0)
071 TGF‐ß‐Mediated Paracrine Regulation of Keratinocyte Wound Closure (2004) (0)
Is Vitamin D Status an Early Predictor of Multiple Sclerosis Activity and Progression ? Clinically Isolated Syndrome Patients from the BENEFIT Study (2015) (0)
Abstract 2456: TGF-Beta regulates tumor ECM remodeling and progression to metastasis (2012) (0)
Modulation of transforming growth factor type beta action by oncogenes (1985) (0)
Separation and Characterizationof TranscriptionallyActive and Inactive Nuclear Subfractionsof AKR Mouse Embryo Cells (1976) (0)
Activation of oncogenic k‐ras in glioneuronal precursor cells results in simultaneous expansion of the subventricular zone and infiltrating glioma (2008) (0)
Challenges and Opportunities to Updating Prescribing Information for Longstanding Oncology Drugs (2019) (0)
Effects of Daclizumab HYP on Accumulation of Disability Exclusive of Acute Relapse in Moderately/Severely Disabled Relapsing-Remitting Multiple Sclerosis Patients: Neurophysical Composite Outcome from the DECIDE Study (P3.085) (2016) (0)
Meharry Medical College-Vanderbilt-Ingram Cancer Center Partnership: Partners in eliminating health disparities (2007) (0)
Abstract 2301: Myeloid cells promote fibroblast invasion and lead mammary adenocarcinoma cell invasion. (2013) (0)
Abstract 3840: Bone morphogenetic proteins require the type II TGFβ receptor for growth arrest in mammary tumor cells (2010) (0)
Design and rationale of the determining the effectiveness of early intensive versus escalation approaches for the treatment of relapsing-remitting multiple sclerosis (DELIVER-MS) trial (2018) (0)
Operations, Oversight, and Funding of Cancer Clinical Trials (2010) (0)
Late-G1 effects of C-myc on TGF-beta-induced inhibition of mouse keratinocytes (1995) (0)
Abstract 3292: The exploration of novel strategy for treatment of pancreactic cancer using genetically engineered mice (2011) (0)
Infliximab for the treatment of neurosarcoidosis: a multi-institutional case series (P1.335) (2017) (0)
Abstract LB-143: Interplay between tissue tension and inflammation in pancreatic tumor progression (2014) (0)
CNS infection with C. pneumoniae complicated by multiple strokes (2003) (0)
Signaling Through TGFßRII Is Not Required For Normal Lens Development Or For Myofibroblast Formation (2004) (0)
Abstract 2259: Blockade of CXC chemokines/CXCR2 axis inhibits pancreatic ductal adenocarcinoma progression through anti-angiogenesis (2010) (0)
Summary Conditional inactivation of Tgfbr 2 in cranial neural crest causes cleft palate and calvaria defects (2003) (0)
Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis (2014) (0)
848 TGF-β signal pathway activation regulates restoration of quiescence in the regenerating liver and of the liver mass: body weight ratio after partial hepatectomy (2003) (0)
Chemically transformed akr-mca cells produce multiple transforming growth factors. Abstr. (1983) (0)
Abstract 629: The impact of BMP4 on breast cancer metastasis in an in vivo xenograft mouse model (2016) (0)
Stromal signaling pathways as targets for prevention (2007) (0)
S03 01 SA – TGFβ REGULATION OF CELL PROLIFERATION (1991) (0)
Abstract A85: The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment. (2012) (0)
Abstract 4306: Lack of TGF-β signaling induces a switch from single to collective cell migration in vivo (2012) (0)
Abstract 2845: Dominant-negative TGFβRII (DNIIR) in c-neu-induced mammary carcinoma cells increases metastasis by disturbing vasculogenesis and pericyte balance (2011) (0)
Morphology in Serum-free Cultures of AKR-2 B Cells Growth Factor , and Insulin on DNA and Protein Synthesis and Differential Effects of Epidermal Growth Factor , Transforming Updated (2006) (0)
Cancer Promotes the Establishment and Progression of Colon Receptor Type II Inactivation β Transforming Growth Factor Updated (2004) (0)
The Development and Characterization of a Transgenic Mouse Model Over-Expressing a Truncated TGF(Beta) Type II Receptor in the Prostate (2000) (0)
Carcinomas Deficient Mouse Mammary − β Transforming Growth Factor-Stromally Derived Lysyl Oxidase Promotes Metastasis of Updated (2013) (0)
Abstract 922: Disruption of bone morphogenetic protein receptor 2 accelerates mammary carcinoma metastasis to the lung (2011) (0)
Transforming Growth Factor-β Regulation of Epithelial Proliferation (1991) (0)
Abstract 851: Epidermal growth factor receptor inhibitor erlotinib prolongs survival inKras-mutant pancreatic ductal adenocarcinoma by inhibiting gemcitabine-induced mitogen activated protein kinase signaling activation (2012) (0)
Abstract A45: Molecular targets in early detection and differentiation of inflammatory bowel disease-associated colon-rectal-anal cancer disparities (2011) (0)
Abstract A47: Reciprocal dialogue between cellular and extracellular matrix tension and tissue inflammation in pancreatic tumor progression. (2012) (0)
FromtheDepartmentsof ‡ CancerBiology, § Medicine,**CellandDevelopmentalBiology,and UrologicSurgery,Vanderbilt UniversityMedicalCenterandtheDepartmentofMedicine,VeteransAffairsHospital,Nashville, Tennessee 37232 (2007) (0)
Binding of [ 3 H ] Benzo ( a ) pyrene Metabolites to the AKR Mouse Embryo Cell Line Nuclear Proteins 1 (2006) (0)
Transforming Growth Factor Production by Chemically Transformed Cells 1 (2004) (0)
Coding: Payment Infrastructure for Biomarker Tests for Molecularly Targeted Therapies (2016) (0)
Abstract A50: Genotype tunes PDAC tension to induce matricellular-fibrosis and tumor aggression (2016) (0)
Transforming growth factors and oncogenes (1987) (0)
Abstract A55: A role of bone morphogenetic protein signaling in pancreatic cancer (2015) (0)
Regulated Transformation of Mammary Epithelial Cells by Transforming Growth Factor-Beta 1 (2002) (0)
Mutation Apc Neoplasms Initiated by Induces the Malignant Transformation of Intestinal Receptor Type II Inactivation β Transforming Growth Factor (2006) (0)
Stromal and epithelial TGF-beta signaling in cancer. (2006) (0)
Supportive Policy Environment for Biomarker Tests for Molecularly Targeted Therapies (2016) (0)
Transforming growth factors from embryonic and adult mouse tissues. Abstr. (1982) (0)
Abstract A16: Stromal LOX promotes TGFβR2 null breast cancer metastasis (2013) (0)
Processes to Improve Patient Care (2016) (0)
Supplement II: Abstracts of the international symposium on Skin Carcinogenesis in man and in experimental models. Heidelberg, 29–31 October 1991 (pp S61–S88) (1991) (0)
Pathway Analyses Identify TGFBR2 as Potential Breast CancerSusceptibilityGene:ResultsfromaConsortiumStudy (2012) (0)
Crucial roles of BMP signaling in pancreatic cancer initiation and progression (2016) (0)
Abstract 5005: Deletion of bone morphogenetic protein receptor 1A impairs mammary gland development and tumor formation. (2013) (0)
Transforming Growth Factor ÃŸlInhibits Mouse Keratinocytes Late in Independent of Effects on Gene Transcription1 (2006) (0)
Stromal and epithelial TGF-β signaling in carcinoma initiation and progression (2005) (0)
Abstract 1956: A novel mouse model of breast cancer metastasis to bone (2010) (0)
Specific alterations in cell cycle control mechanisms in chemically transformed mouse embryo cells in culture. Abstr. (1979) (0)
Transforming Growth Factor fi and Cell Cycle Regulation' (2006) (0)

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