James Collins

Q: What Schools Are Affiliated With James Collins

James Collins is affiliated with the following schools: University of California, Berkeley, Boston University, University of Oxford, College of the Holy Cross, Massachusetts Institute of Technology, Linköping University, University of Illinois Urbana-Champaign, University of Texas Southwestern Medical Center, Harvard University, Heidelberg University

James Collins 's AcademicInfluence.com Rankings

James Collins

Engineering

#418

World Rank

#717

Historical Rank

#191

USA Rank

Biomedical Engineering

#14

World Rank

#14

Historical Rank

USA Rank

engineering Degrees

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Engineering

James Collins 's Degrees

PhD Biomedical Engineering University of California, Berkeley
Masters Biomedical Engineering University of California, Berkeley
Bachelors Biomedical Engineering University of California, Berkeley

Why Is James Collins Influential?

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According to Wikipedia, James Joseph Collins is an American bioengineer who serves as the Termeer Professor of Medical Engineering & Science at the Massachusetts Institute of Technology . Collins conducted research showing that artificial intelligence approaches can be used to discover novel antibiotics, such as halicin and abaucin. He serves as the Director of the Antibiotics-AI Project at MIT, which is supported by The Audacious Project, and is the faculty lead for life sciences at the MIT Jameel Clinic.

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James Collins 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Construction of a genetic toggle switch in Escherichia coli (2000) (4024)
A practical method for calculating largest Lyapunov exponents from small data sets (1993) (2951)
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. (2010) (2537)
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics (2007) (2358)
Stochasticity in gene expression: from theories to phenotypes (2005) (2284)
How antibiotics kill bacteria: from targets to networks (2010) (1750)
Nucleic acid detection with CRISPR-Cas13a/C2c2 (2017) (1699)
Large-Scale Mapping and Validation of Escherichia coli Transcriptional Regulation from a Compendium of Expression Profiles (2007) (1534)
Wisdom of crowds for robust gene network inference (2012) (1506)
The Immunological Genome Project: networks of gene expression in immune cells (2008) (1448)
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6 (2018) (1227)
Synthetic biology: applications come of age (2010) (1224)
Inferring Genetic Networks and Identifying Compound Mode of Action via Expression Profiling (2003) (1192)
Highly-efficient Cas9-mediated transcriptional programming (2014) (1084)
Open-loop and closed-loop control of posture: A random-walk analysis of center-of-pressure trajectories (2004) (1019)
Cellular Decision Making and Biological Noise: From Microbes to Mammals (2011) (953)
Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components (2016) (881)
A Deep Learning Approach to Antibiotic Discovery (2020) (832)
Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis. (2010) (796)
Metabolite-Enabled Eradication of Bacterial Persisters by Aminoglycosides (2011) (756)
Dispersing biofilms with engineered enzymatic bacteriophage (2007) (732)
Engineered gene circuits (2002) (726)
Stochastic resonance without tuning (1995) (721)
Reverse engineering gene networks using singular value decomposition and robust regression (2002) (695)
A brief history of synthetic biology (2014) (642)
Computational studies of gene regulatory networks: in numero molecular biology (2001) (630)
Noise-based switches and amplifiers for gene expression. (2000) (626)
Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip (2015) (625)
Programmable cells: interfacing natural and engineered gene networks. (2004) (617)
Phenotypic consequences of promoter-mediated transcriptional noise. (2006) (616)
Antibiotics induce redox-related physiological alterations as part of their lethality. (2014) (613)
Biomechanical gait alterations independent of speed in the healthy elderly: evidence for specific limiting impairments. (1998) (613)
Definitions and guidelines for research on antibiotic persistence (2019) (575)
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (2011) (569)
Synthetic Gene Networks That Count (2009) (566)
Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria (2013) (562)
Toehold Switches: De-Novo-Designed Regulators of Gene Expression (2014) (551)
Aging, muscle activity, and balance control: physiologic changes associated with balance impairment. (2003) (549)
Next-Generation Machine Learning for Biological Networks (2018) (547)
Vibrating insoles and balance control in elderly people (2003) (542)
Bacterial charity work leads to population-wide resistance (2010) (537)
Engineered riboregulators enable post-transcriptional control of gene expression (2004) (532)
Coupled nonlinear oscillators and the symmetries of animal gaits (1993) (497)
Antibiotics and the gut microbiota. (2014) (495)
Paper-Based Synthetic Gene Networks (2014) (481)
Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death (2008) (480)
DIVERSITY-BASED, MODEL-GUIDED CONSTRUCTION OF SYNTHETIC GENE NETWORKS WITH PREDICTED FUNCTIONS (2009) (471)
Prediction and measurement of an autoregulatory genetic module (2003) (470)
Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy (2009) (470)
Reverse engineering gene networks: Integrating genetic perturbations with dynamical modeling (2003) (469)
A community effort to assess and improve drug sensitivity prediction algorithms (2014) (468)
Antibiotic efficacy is linked to bacterial cellular respiration. (2015) (458)
CellNet: Network Biology Applied to Stem Cell Engineering (2014) (453)
Antibiotic Treatment Expands the Resistance Reservoir and Ecological Network of the Phage Metagenome (2013) (444)
Noise-enhanced tactile sensation (1996) (432)
Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli (2007) (419)
MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium (2009) (413)
Syntrophic exchange in synthetic microbial communities (2014) (405)
Microbial persistence and the road to drug resistance. (2013) (398)
Oxidation of the Guanine Nucleotide Pool Underlies Cell Death by Bactericidal Antibiotics (2012) (395)
Chemogenomic profiling on a genome-wide scale using reverse-engineered gene networks (2005) (394)
Reconstruction expansion as a geometry-based framework for choosing proper delay times (1994) (390)
Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative Damage in Mammalian Cells (2013) (386)
Role of reactive oxygen species in antibiotic action and resistance. (2009) (386)
Universal Chimeric Antigen Receptors for Multiplexed and Logical Control of T Cell Responses (2018) (383)
Signaling-Mediated Bacterial Persister Formation (2011) (373)
Synthetic Biology Moving into the Clinic (2011) (370)
Noise-enhanced information transmission in rat SA1 cutaneous mechanoreceptors via aperiodic stochastic resonance. (1996) (365)
Symmetry in locomotor central pattern generators and animal gaits (1999) (361)
RNA synthetic biology (2006) (352)
Next-Generation Synthetic Gene Networks (2009) (350)
A bottom-up approach to gene regulation (2006) (346)
Bone marrow–on–a–chip replicates hematopoietic niche physiology in vitro (2014) (344)
Noise‐enhanced balance control in patients with diabetes and patients with stroke (2006) (340)
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production (2012) (336)
Deconstructing transcriptional heterogeneity in pluripotent stem cells (2014) (335)
Noise-enhanced human balance control. (2002) (330)
Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage. (2015) (328)
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma (2012) (327)
Reduced hip extension during walking: healthy elderly and fallers versus young adults. (2001) (316)
A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions (2012) (313)
Antibiotic-induced bacterial cell death exhibits physiological and biochemical hallmarks of apoptosis. (2012) (311)
Noise in human muscle spindles (1996) (301)
Programmable bacteria detect and record an environmental signal in the mammalian gut (2014) (298)
Synchronizing genetic relaxation oscillators by intercell signaling (2002) (295)
Age-related changes in open-loop and closed-loop postural control mechanisms (2004) (295)
The effects of visual input on open-loop and closed-loop postural control mechanisms (2004) (292)
Reprogramming of T cells from human peripheral blood. (2010) (288)
A Tunable Genetic Switch Based on RNAi and Repressor Proteins for Regulating Gene Expression in Mammalian Cells (2007) (279)
Designer gene networks: Towards fundamental cellular control. (2001) (278)
An enhanced CRISPR repressor for targeted mammalian gene regulation (2018) (269)
Cas9 gRNA engineering for genome editing, activation and repression (2015) (262)
Complex cellular logic computation using ribocomputing devices (2017) (261)
Effects of Colored Noise on Stochastic Resonance in Sensory Neurons (1999) (250)
Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development (2010) (249)
Comparative Analysis of Cas9 Activators Across Multiple Species (2016) (247)
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. (2013) (246)
LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. (2016) (244)
Synthetic biology devices for in vitro and in vivo diagnostics (2015) (244)
Portable, On-Demand Biomolecular Manufacturing (2016) (243)
Dissecting Engineered Cell Types and Enhancing Cell Fate Conversion via CellNet (2014) (239)
A modular network for legged locomotion (1998) (230)
The redundant nature of locomotor optimization laws. (1995) (228)
Integrating Biological Redesign: Where Synthetic Biology Came From and Where It Needs to Go (2014) (227)
Combinatorial promoter design for engineering noisy gene expression (2007) (223)
“Deadman” and “Passcode” microbial kill switches for bacterial containment (2015) (220)
Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control. (2017) (215)
Bacterial Metabolism and Antibiotic Efficacy (2017) (214)
The engineering of gene regulatory networks. (2003) (212)
Hard-wired central pattern generators for quadrupedal locomotion (1994) (211)
Unraveling the physiological complexities of antibiotic lethality. (2015) (208)
Synthetic gene network for entraining and amplifying cellular oscillations. (2002) (207)
CRISPR-based diagnostics (2021) (203)
Noise-mediated enhancements and decrements in human tactile sensation (1997) (195)
Age-related changes in the initiation of gait: degradation of central mechanisms for momentum generation. (1998) (195)
Adult somatic stem cells in the human parasite, Schistosoma mansoni (2013) (188)
Noise-enhanced balance control in older adults (2002) (187)
Heterogeneous bacterial persisters and engineering approaches to eliminate them. (2011) (187)
Designing microbial consortia with defined social interactions (2018) (187)
A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action (2019) (184)
Tunable protein degradation in bacteria (2014) (183)
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators (2010) (182)
The transcriptional landscape of hematopoietic stem cell ontogeny. (2012) (178)
Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli. (2009) (178)
DYNAMIC CONTROL OF CARDIAC ALTERNANS (1997) (177)
Programmable CRISPR-responsive smart materials (2019) (173)
Noise-enhanced vibrotactile sensitivity in older adults, patients with stroke, and patients with diabetic neuropathy. (2002) (172)
The Role of the Quadriceps in Controlling Impulsive Forces around Heel Strike (1990) (171)
Noise-enhanced human sensorimotor function (2003) (167)
Wearable materials with embedded synthetic biology sensors for biomolecule detection (2021) (166)
A multiply redundant genetic switch ‘ locks in ’ the transcriptional signature of regulatory T cells (2012) (163)
Upright, correlated random walks: A statistical-biomechanics approach to the human postural control system. (1995) (163)
Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma (2016) (162)
A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers (2018) (160)
A network biology approach to prostate cancer (2007) (160)
Genetic switchboard for synthetic biology applications (2012) (160)
Tunable Signal Processing in Synthetic MAP Kinase Cascades (2011) (158)
Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells (2015) (157)
The measurement and analysis of age-related changes in Caenorhabditis elegans. (2008) (150)
Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance (2013) (149)
Antibiotic-Induced Changes to the Host Metabolic Environment Inhibit Drug Efficacy and Alter Immune Function. (2017) (147)
Tuning and controlling gene expression noise in synthetic gene networks (2010) (143)
Impulsive forces during walking and their clinical implications. (1989) (139)
Nucleic acid detection with CRISPR-Cas 13 a / C 2 c 2 Citation (2017) (138)
Cell-free biosensors for rapid detection of water contaminants (2020) (136)
Fungicidal drugs induce a common oxidative-damage cellular death pathway. (2013) (136)
Probiotic strains detect and suppress cholera in mice (2018) (133)
Microbial environments confound antibiotic efficacy. (2011) (131)
Hexapodal gaits and coupled nonlinear oscillator models (1993) (131)
Using electrical noise to enhance the ability of humans to detect subthreshold mechanical cutaneous stimuli. (1998) (129)
Using Targeted Chromatin Regulators to Engineer Combinatorial and Spatial Transcriptional Regulation (2014) (129)
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate (2019) (125)
An Atlas for Schistosoma mansoni Organs and Life-Cycle Stages Using Cell Type-Specific Markers and Confocal Microscopy (2011) (124)
Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants (2021) (124)
Next-generation biocontainment systems for engineered organisms (2018) (120)
Targeting Antibiotic Tolerance, Pathogen by Pathogen (2018) (120)
Noise shaping in populations of coupled model neurons. (1999) (118)
Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni (2013) (117)
Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans (2006) (113)
Clinically relevant mutations in core metabolic genes confer antibiotic resistance (2021) (112)
A CRISPR Cas9-based gene drive platform for genetic interaction analysis in Candida albicans (2017) (108)
microRNA regulatory network inference identifies miR-34a as a novel regulator of TGF-β signaling in glioblastoma. (2012) (107)
Enhancing tactile sensation in older adults with electrical noise stimulation (2002) (105)
A multiple redundant genetic switch locks in the transcriptional signature of T regulatory cells (2012) (105)
Functional characterization of bacterial sRNAs using a network biology approach (2011) (100)
The effects of stochastic galvanic vestibular stimulation on human postural sway (1999) (99)
Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells. (2014) (98)
Understanding and Sensitizing Density-Dependent Persistence to Quinolone Antibiotics. (2017) (98)
Evidence that coronavirus superspreading is fat-tailed (2020) (96)
Epigenetic Landscapes Explain Partially Reprogrammed Cells and Identify Key Reprogramming Genes (2012) (96)
Chromatin regulation at the frontier of synthetic biology (2015) (96)
Roles for the transcription elongation factor NusA in both DNA repair and damage tolerance pathways in Escherichia coli (2010) (95)
Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks. (2017) (93)
Iterative plug-and-play methodology for constructing and modifying synthetic gene networks (2012) (93)
Transcriptome Analysis Identifies Regulators of Hematopoietic Stem and Progenitor Cells (2013) (92)
Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria (2020) (91)
Complex signal processing in synthetic gene circuits using cooperative regulatory assemblies (2019) (89)
Stochastic Resonance in Ensembles of Nondynamical Elements: The Role of Internal Noise (1997) (88)
BioBits™ Explorer: A modular synthetic biology education kit (2018) (88)
Synchronization of noisy systems by stochastic signals. (1999) (87)
A network biology approach to aging in yeast (2009) (85)
A group-theoretic approach to rings of coupled biological oscillators (1994) (82)
Kinetic alterations independent of walking speed in elderly fallers. (2000) (82)
Chemogenomics and orthology‐based design of antibiotic combination therapies (2016) (81)
Muscle-Ligament Interactions at the Knee during Walking (1991) (80)
Human Balance out of Equilibrium: Nonequilibrium Statistical Mechanics in Posture Control (1998) (78)
Reconstruction of complex single-cell trajectories using CellRouter (2018) (77)
CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms (2018) (75)
A role for the bacterial GATC methylome in antibiotic stress survival (2016) (74)
A Deep Learning Approach to Antibiotic Discovery (2020) (74)
A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding (2020) (73)
Enhancing human balance control with galvanic vestibular stimulation (2001) (73)
Understanding Biological Regulation Through Synthetic Biology. (2018) (71)
Engineered Phagemids for Nonlytic, Targeted Antibacterial Therapies. (2015) (71)
Robust Identification of Large Genetic Networks (2003) (71)
BioBits™ Bright: A fluorescent synthetic biology education kit (2018) (70)
High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR/Cas9 in yeast (2018) (70)
Predicting the dynamic postural control response from quiet-stance behavior in elderly adults. (2003) (69)
De-Novo-Designed Translation-Repressing Riboregulators for Multi-Input Cellular Logic (2019) (69)
Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice (2014) (67)
Move over ZFNs (2011) (67)
Antibiotic efficacy-context matters. (2017) (67)
Engineering living therapeutics with synthetic biology (2021) (66)
Creating Single-Copy Genetic Circuits. (2016) (63)
A deep learning approach to programmable RNA switches (2020) (62)
A Blueprint for a Synthetic Genetic Feedback Controller to Reprogram Cell Fate. (2017) (61)
A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection (2020) (61)
Symmetry-breaking bifurcation: A possible mechanism for 2:1 frequency-locking in animal locomotion (1992) (59)
Systematically improved in vitro culture conditions reveal new insights into the reproductive biology of the human parasite Schistosoma mansoni (2018) (58)
Coherence resonance in excitable and oscillatory systems: the essential role of slow and fast dynamics. (1999) (58)
Predictive biology: modelling, understanding and harnessing microbial complexity (2020) (57)
Translating the noise (2002) (57)
A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity. (2014) (57)
Antioxidant Strategies to Tolerate Antibiotics (2011) (55)
Balancing act [noise based sensory enhancement technology] (2005) (54)
Mechanism of stochastic resonance enhancement in neuronal models driven by 1/f noise. (1999) (54)
Publisher Correction: Definitions and guidelines for research on antibiotic persistence (2019) (53)
Deep learning identifies synergistic drug combinations for treating COVID-19 (2021) (52)
Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria (2014) (52)
Posttranscriptional control of Klebsiella pneumoniae nif mRNA stability by the nifL product (1986) (52)
A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite (2013) (52)
Suppressing arrhythmias in cardiac models using overdrive pacing and calcium channel blockers. (2002) (52)
Differential splicing across immune system lineages (2013) (51)
Using deep learning for dermatologist-level detection of suspicious pigmented skin lesions from wide-field images (2021) (51)
Identification of new markers for the Schistosoma mansoni vitelline lineage☆ (2016) (51)
Drinking and Crime (1982) (50)
Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling. (2017) (48)
Boosting bacterial metabolism to combat antibiotic resistance. (2015) (48)
Whole mount in situ hybridization methodology for Schistosoma mansoni. (2011) (47)
Synthetic Biology: Bits and pieces come to life (2012) (46)
A theory for controlling cell cycle dynamics using a reversibly binding inhibitor. (1998) (46)
DNA sense-and-respond protein modules for mammalian cells (2015) (44)
Evolving complex dynamics in electronic models of genetic networks. (2004) (44)
Regulation of Physiologic Actions of LRRK2: Focus on Autophagy (2011) (43)
Stem cell progeny contribute to the schistosome host-parasite interface (2016) (42)
It's No Fluke: The Planarian as a Model for Understanding Schistosomes (2013) (42)
RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming. (2016) (42)
Engineering advanced logic and distributed computing in human CAR immune cells (2021) (42)
Size matters: network inference tackles the genome scale (2007) (41)
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types (2018) (41)
Synthetic biology platform technologies for antimicrobial applications. (2016) (41)
The Anticonvulsant Ethosuximide Disrupts Sensory Function to Extend C. elegans Lifespan (2008) (40)
Predicting cerebral blood flow response to orthostatic stress from resting dynamics: effects of healthy aging. (2001) (39)
Platyhelminthes (2017) (39)
Synthetic biology in the clinic: engineering vaccines, diagnostics, and therapeutics (2021) (39)
Protein interactions: Unspinning the web (2001) (38)
Genomic approaches to deconstruct pluripotency. (2011) (38)
Eradicating Bacterial Persisters with Combinations of Strongly and Weakly Metabolism-Dependent Antibiotics. (2020) (37)
Assessing muscle stiffness from quiet stance in Parkinson's disease (1999) (36)
Parallel bimodal single-cell sequencing of transcriptome and chromatin accessibility (2019) (36)
Home care for the dying child. A parent's perception. (1998) (36)
ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors (2017) (35)
Influence of gait parameters on the loading of the lower limb. (1989) (35)
Role of the spoT gene product and manganese ion in the metabolism of guanosine 5'-diphosphate 3'-diphosphate in Escherichia coli. (1979) (35)
Enhancing aperiodic stochastic resonance through noise modulation. (1998) (35)
The effects of spaceflight on open-loop and closed-loop postural control mechanisms: human neurovestibular studies on SLS-2 (2004) (34)
Using Engineered Bacteria to Characterize Infection Dynamics and Antibiotic Effects In Vivo. (2017) (34)
Introduction to focus issue: quantitative approaches to genetic networks. (2013) (32)
Tissue Degeneration following Loss of Schistosoma mansoni cbp1 Is Associated with Increased Stem Cell Proliferation and Parasite Death In Vivo (2016) (31)
Benchmarking AlphaFold‐enabled molecular docking predictions for antibiotic discovery (2022) (31)
Using weak impulses to suppress traveling waves in excitable media. (1999) (29)
Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality (2021) (29)
Schistosomiasis as a disease of stem cells (2016) (29)
Biophysics: Fishing for function in noise (1999) (29)
Lethality of MalE-LacZ hybrid protein shares mechanistic attributes with oxidative component of antibiotic lethality (2017) (28)
ENCODING CHAOS IN NEURAL SPIKE TRAINS (1998) (28)
Systems Biology Strikes Gold (2009) (28)
The effects of stochastic monopolar galvanic vestibular stimulation on human postural sway. (2002) (28)
CONTROLLED MOVEMENT AND SUPPRESSION OF SPIRAL WAVES IN EXCITABLE MEDIA (1998) (28)
Synthetic biology: How best to build a cell (2014) (27)
Control of Klebsiella pneumoniae nif mRNA synthesis (1985) (27)
The dynamics of quasi-static posture control (1999) (27)
Precise Cas9 targeting enables genomic mutation prevention (2016) (26)
REAL-TIME EXPERIMENTAL CONTROL OF A SYSTEM IN ITS CHAOTIC AND NONCHAOTIC REGIMES (1997) (26)
Repression of nitrogen fixation in Klebsiella pneumoniae at high temperature (1984) (26)
Deep-Learning Resources for Studying Glycan-Mediated Host-Microbe Interactions. (2020) (25)
A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria (2019) (25)
Real-time, adaptive, model-independent control of low-dimensional chaotic and nonchaotic dynamical systems (1997) (25)
Gene regulation: Neutralizing noise in gene networks (2000) (25)
Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing (2019) (24)
A pathway and genetic factors contributing to elevated gene expression noise in stationary phase. (2007) (24)
The distribution of genomic variations in human iPSCs is related to replication-timing reorganization during reprogramming. (2014) (23)
Insulating gene circuits from context by RNA processing (2012) (22)
Signal Processing in Single Cells (2005) (22)
An engineered live biotherapeutic for the prevention of antibiotic-induced dysbiosis (2022) (22)
It's a small world (2015) (21)
Definitions and guidelines for research on antibiotic persistence (2019) (21)
Rapid, Low-Cost Detection of Water Contaminants Using Regulated In Vitro Transcription (2019) (21)
Networking Opportunities for Bacteria (2008) (20)
Creating CRISPR-responsive smart materials for diagnostics and programmable cargo release (2020) (20)
Control of chaos in excitable physiological systems: A geometric analysis. (1997) (20)
Transient growth inhibition of Escherichia coli K-12 by ion chelators: "in vivo" inhibition of ribonucleic acid synthesis (1979) (20)
Visualizing the effects of filtering chaotic signals (1994) (19)
Zfp322a Regulates Mouse ES Cell Pluripotency and Enhances Reprogramming Efficiency (2014) (19)
NF-YB Regulates Spermatogonial Stem Cell Self-Renewal and Proliferation in the Planarian Schmidtea mediterranea (2016) (18)
Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond. (2021) (17)
RNA-responsive elements for eukaryotic translational control (2021) (17)
A lophotrochozoan-specific nuclear hormone receptor is required for reproductive system development in the planarian. (2014) (16)
Rewiring Bacteria, Two Components at a Time (2008) (16)
Point-of-Care Devices to Detect Zika and Other Emerging Viruses. (2020) (15)
Antagonistic-synergistic muscle action at the knee during competitive weightlifting (1994) (15)
Mass Spectrometry Imaging and Identification of Peptides Associated with Cephalic Ganglia Regeneration in Schmidtea mediterranea* (2016) (15)
A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (15)
Tryptophan hydroxylase Is Required for Eye Melanogenesis in the Planarian Schmidtea mediterranea (2015) (15)
A male-derived nonribosomal peptide pheromone controls female schistosome development (2022) (14)
Continuous bioactivity-dependent evolution of an antibiotic biosynthetic pathway (2020) (13)
Targeted erythropoietin selectively stimulates red blood cell expansion in vivo (2016) (13)
Tuning stochastic resonance (1995) (12)
Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies (2022) (12)
Frequency Control of an Oscillatory Reaction by Reversible Binding of an Autocatalyst (1999) (12)
Resource Paper-Based Synthetic Gene Networks (2014) (12)
Plug-and-play with RNA (2005) (12)
Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy (2013) (12)
Molecular genetic analysis of AvrRpt2 activity in promoting virulence of Pseudomonas syringae. (2005) (12)
A single-cell RNAseq atlas of the pathogenic stage of Schistosoma mansoni identifies a key regulator of blood feeding (2020) (11)
Increased energy demand from anabolic-catabolic processes drives β-lactam antibiotic lethality. (2021) (11)
Using Natural Language Processing to Learn the Grammar of Glycans (2020) (10)
Systems biology makes it personal. (2009) (10)
SchistoCyte Atlas: A Single-Cell Transcriptome Resource for Adult Schistosomes. (2021) (10)
Noise-Enhanced Human Sensorimotor Function Using Stochastic Resonance to Enhance Somatosensation and Improve Performance of the Human Balance Control System (2003) (9)
Alternative Splicing of MBD 2 Supports Self-Renewal in Human Pluripotent Stem Cells (2014) (9)
Gene regulation: hacking the network on a sugar high. (2008) (9)
Dioxin exposure. (1993) (8)
Anomalous COVID-19 tests hinder researchers (2021) (8)
The dying child (2003) (8)
Advances in parenteral injection devices and aids (2016) (8)
Editorial–Synthetic Biology (2010) (8)
Molecular biology. Signal processing in single cells. (2005) (7)
Stochastic regulation of gene expression (2000) (7)
Defining cellular identity through network biology (2014) (7)
The Effect of Compositional Context on Synthetic Gene Networks (2016) (7)
Stress/Burnout Report. (1980) (6)
SweetOrigins: Extracting Evolutionary Information from Glycans (2020) (6)
A rotifer-derived paralytic compound prevents transmission of schistosomiasis to a mammalian host (2018) (6)
De-Novo-Designed Translational Repressors for Multi-Input Cellular Logic (2018) (6)
Random Walking during Quiet Standing 1 (6)
Methods for Studying the Germline of the Human Parasite Schistosoma mansoni. (2017) (6)
CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development (2022) (6)
Enhancing Human Balance Control by Apply Random Vibrations to the Ankle Tendons: 2392 (2006) (5)
And the Noise Played on: Stochastic Gene Expression and HIV-1 Infection (2005) (5)
Abstract 4920: Gene network models identify targets for mammary tumor normalization (2012) (5)
Analysis of Schistosoma mansoni Extracellular Vesicles Surface Glycans Reveals Potential Immune Evasion Mechanism and New Insights on Their Origins of Biogenesis (2021) (5)
Deep Learning for RNA Synthetic Biology (2019) (5)
Federal Drug Data for National Policy. (1990) (4)
Erratum: Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells (2012) (4)
Controlling Neuronal Noise Using Chaos Control (1995) (4)
The sound of silence: Transgene silencing in mammalian cell engineering. (2022) (4)
Oligonucleotide Array CGH Analysis of a Robust Whole Genome Amplification Method (2007) (4)
Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function (2020) (4)
CRISPR Guide RNA Cloning for Mammalian Systems. (2018) (4)
Vibrating Insoles Improve Balance in Diabetic Patients with Peripheral Neuropathy (2004) (4)
Cellular signal processing: out of one, many. (2012) (3)
The Schistosoma mansoni nuclear receptor FTZ-F1 maintains esophageal gland function via transcriptional regulation of meg-8.3 (2021) (3)
Inferring Microbial Genetic Networks Statistical learning applied to transcript responses help to gauge how genes influence one another and to identify complex networks (2004) (3)
Editorial overview: Antimicrobials: grappling with the complexities of antibiotics and resistance. (2014) (3)
SETDB1 acts as a topological accessory to Cohesin via an H3K9me3-independent, genomic shunt for regulating cell fates (2022) (3)
Convergent evolution of a genotoxic stress response in a parasite-specific p53 homolog (2022) (3)
Postural control mechanisms in normal and toe-standing (2001) (3)
BONE MARROW-ON-A-CHIP (2012) (3)
Corrigendum: Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma (2012) (3)
Colonization with heterologous bacteria reprograms a Caenorhabditis elegans nutritional phenotype (2020) (3)
Making a noisy gene: HDACs turn up the static. (2012) (3)
Simultaneous detection of SARS-CoV-2 RNA and host antibodies enabled by a multiplexed electrochemical sensor platform (2021) (3)
Correction: Genome-Wide Analyses Reveal a Role for Peptide Hormones in Planarian Germline Development (2015) (3)
A Nonlinear Dynamical Analysis Of The Human Postural Control System (1991) (2)
Engineering synthetic bacteriophage to combat antibiotic-resistant bacteria (2009) (2)
miR-34a as a novel regulator of TGFβ signaling in GBM (2012) (2)
Ribocomputing devices for sophisticated in vivo logic computation (2016) (2)
Bacteria as control engineers. (2011) (2)
Information measures quantifying aperiodic stochastic (1996) (2)
Wavelets of excitability in sensory neurons. (2001) (2)
Engineering microbial peer pressure (2019) (2)
Tactile stimulation of insoles and balance control in elderly people (2004) (2)
Chapter 6 Controlling cardiac arrhythmias: The relevance of nonlinear dynamics (2001) (2)
A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans (2017) (2)
Reply to Blair et al.: Dose-dependent effects and oxidative stress responses in antibiotic tolerance in Salmonella typhimurium (2013) (2)
Overcoming Antibiotic Resistance. (2019) (2)
High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR/Cas9 (2017) (2)
Journal club (2009) (2)
A Systems Biology Approach to Study the Acquisition of Adult Repopulating Potential During Hematopoietic Stem Cell Ontogeny. (2009) (2)
Data for A novel rotifer derived alkaloid paralyzes schistosome larvae and prevents infection (2019) (1)
PLOS Pathogens 2016 Reviewer and Editorial Board Thank You (2017) (1)
Resource Creating Single-Copy Gen etic Circuits Graphical (2016) (1)
Author response: Stem cell progeny contribute to the schistosome host-parasite interface (2016) (1)
Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (1)
A novel rotifer-derived alkaloid paralyzes schistosome larvae and prevents infection (2018) (1)
Single-cell RNA-seq analyses show that long non-coding RNAs are conspicuously expressed in Schistosoma mansoni gamete and tegument progenitor cell populations (2022) (1)
Reconstruction of complex single-cell trajectories using CellRouter (2018) (1)
Labeling of the Schistosoma mansoni Tegument. (2020) (1)
A CRISPR-based assay for the detection of opportunistic infections post-transplantation and for the monitoring of transplant rejection (2020) (1)
Physician incentives in a managed care world. (1994) (1)
A Framework for Addressing Health Issues (2002) (1)
LIN 28 Regulates Stem Cel l Metabolism and Conversion to Primed Pluripotency Graphical (1)
Engineering life: Building a FAB for Biology. (Cover story) (2006) (1)
EFFECT OF ELECTRICAL NOISE ON BALANCE CONTROL IN ELDERLY ADULTS (2002) (1)
Expanding and enhancing our antibacterial arsenal. (2011) (1)
Chapter 1 Electrical stimulation of the somatosensory system (2001) (1)
Central role for RNase YbeY in Hfq-dependent and Hfq-independent small-RNA regulation in bacteria (2014) (1)
Author response: Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni (2013) (1)
Engineering Models to Scale (2016) (1)
Carbohydrate Ingestion During Exhaustive High-intensity Intermittent Shuttle Running In The Heat: 58 10:45 AM - 11:00 AM (2005) (1)
Harnessing synthetic biology to enhance ocean health. (2023) (1)
Stochastic and chaos analyses of postural sway: A comparative approach (1994) (1)
Enhancing nutritional niche and host defenses by modifying the gut microbiome (2022) (1)
Spike-frequency adaptation improves noise-shaping in model neuronal networks (2000) (1)
Nesting Results and Initial Habitat Assessment of the Nesting Box Trail for Sialia sialis (Eastern Bluebird) In the Powell River Project Education Center (2007) (1)
Cell Metabolism Perspective Bacterial Metabolism and Antibiotic Efficacy (2019) (1)
Autocatalytic Gene Expression : In Numero Quantitative Predictions , In Vivo Stochastic Dynamics (2002) (1)
Suppressing arrhythmias in cardiac models with overdrive pacing (2000) (1)
Developing a lab-in-a-box and low-cost paper-based sensors for ZIKV and CHIKV diagnosis in Latin America (2021) (1)
Enhancing aperiodic stochastic resonance through noisemodulationCarson (1998) (0)
Highly orthogonal programmable riboregulators for complex digital logic in E. Coli (2013) (0)
Foti Bactericidal Antibiotics Oxidation of the Guanine Nucleotide Pool Underlies Cell Death (2012) (0)
Bactericidal Antibiotics In duce Toxic Metabolic Perturbations that Lead to Cellular Damage Graphical Abstract Highlights (2015) (0)
The Role of Kinesin-8 Proteins in Kinetochore Movements and Spindle Dynamics in Fission Yeast (2013) (0)
Kalghatgi Damage in Mammalian Cells Bactericidal Antibiotics Induce Mitochondrial Dysfunction and Oxidative (2013) (0)
Program/Abstract # 414The planarian Schmidtea mediterranea as a free-living model for understanding and controlling flatworm parasites (2011) (0)
Biophysical Constraints A rising from Compositional Context in Synthetic Gene Networks Graphical (2017) (0)
Reprogramming cell fate : Systemic failures and their mitigation through feedback control (2016) (0)
Abstract 2948: The role of the RNA binding protein LIN28B in neuroblastoma (2012) (0)
Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types (2018) (0)
Su2012 - Utility of Self-Expandable Metallic Stent in the Management of Gastric Outlet Obstruction (2018) (0)
Neuropeptide signaling in planarian sexual development and regeneration (2011) (0)
Abstract 4924: Gene network inference models reveal novel key mediators of mammary tumorigenesis (2011) (0)
Diagnosis of gene network responsible for cold acclimation in Chinese cabbages (2007) (0)
Phenotypic consequences of promoter-mediated transcriptional noise: Experiment and computational modeling (2007) (0)
ICLES Loss of the homeostatic balance with lower glutathione causes an excess of ROSs (2017) (0)
The good, the bad, and the ugly: From planarians to parasites. (2022) (0)
Understanding biological regulation through forward synthesis (2018) (0)
Biophysical Constraints Arising From Relative Gene OrientaCompositional Contexttion in Synthetic Gene Networks (2017) (0)
Reverse engineering gene regulatory networks (2005) (0)
A Systems Biology Platform for Characterizing Regulatory and Metabolic Pathways that Influence and Control Microbial Hydrogen Production (2013) (0)
Stochastic Fluctuations in Gene Regulation (2005) (0)
How stability can lead to variability: Induction timecourse of a eukaryotic gene (2006) (0)
An enhanced CRISPR repressor for targeted mammalian gene regulation (2018) (0)
How stability can lead to variability: An example from eukaryotic gene expression (2006) (0)
DiSCs – Domains involving SETDB1 and Cohesin are critical regulators of genome topology and stem cell fate (2022) (0)
Resource Portable , On-Demand Biomolecular Manufacturing Graphical (2016) (0)
Engineering Gene Regulatory Networks: A Reductionist Approach to Systems Biology (2005) (0)
HIV-1 infection alters cytokine and chemokine networks that influence innate immunity in the lung (2007) (0)
Tunable protein degradation in bacteria The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2014) (0)
Engineered gene networks (2003) (0)
Convergent evolution of “genome guardian” functions in a parasite-specific p53 homolog (2021) (0)
Schistosome Sulfotransferases: Mode of Action, Expression and Localization (2022) (0)
Diversity-Based Design of Synthetic Gene Networks with Desired Functions (2009) (0)
Design and Construction of Genetic Applets (2003) (0)
Synthetic Biology: Physical Biology by Design (2019) (0)
Synthetic Biology as a Tool for Discovery of Biophysical Mechanisms (2016) (0)
- Ramirez Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria (2013) (0)
in vitro egg production by the human parasite Schistosoma mansoni (2018) (0)
CRISPR technologies : a toolkit for making genetically intractable microbes tractable (2018) (0)
Abstract LB-165: Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma (2016) (0)
Microbial community-wide effects of antibiotics (2014) (0)
Assessing Muscle Sti ness from Quiet Stance : Applicability to Parkinson ' s Disease (2007) (0)
A WhiteBox Machine Learning Approach for Revealing Antibiotic Mechanisms of Action Graphical (2019) (0)
POSTURAL CONTROL AND MUSCLE ACTIVITY DURING QUIET STANDING IN COMMUNITY DWELLING ELDERLY. (2001) (0)
CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development (2022) (0)
Author Correction: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors (2019) (0)
The Dynamics of Quasistatic Posture Control (1999) (0)
Amy Brock Prevents Mammary Tumor Progression in Mice by Intraductal Injection of siRNA Lipidoid Nanoparticles HoxA 1 Silencing (2013) (0)
Motor Control Changes In Ambulatory Elderly (2001) (0)
Systems biology promises to personalize medicine via network-based biomarkers that predict therapeutic effectiveness. Toward this goal, Chang et al. (2009) recently introduced a systems-based approach to break down oncogenic signaling networks into modules that predict the effectiveness of pathway-s (2009) (0)
Title : High-throughput creation and functional profiling of eukaryotic DNA sequence variant libraries using CRISPR / Cas 9 (2017) (0)
Noise-Enhanced Sensorimotor Function (2004) (0)
The effects of visual input on postural stability (1994) (0)
POSTURAL CONTROL AND GAIT DEFICIENCIES IN ELDERLY ADULTS 892 (1996) (0)
Systems-Level Analysis of Stem Cells in the Larval Stage of the Human Parasitic Flatworm Schistosoma (2013) (0)
Apparatus to improve balance and gait in humans and prevent foot injuries (2004) (0)
Transcriptional insights into the CD8[superscript +] T cell response to infection and memory T cell formation (2013) (0)
An Ising model description of sigma-delta data converters (2000) (0)
Gait initiation on toes: a more efficient generation of forward momentum (2000) (0)
A Pinned Polymer Model of Posture (1995) (0)
Chapter 17 – Visualizing the effects of filtering chaotic signals (1998) (0)
Stochastic resonance and the tuning of muscle spindles by fusimotor drive (1997) (0)
Abstract P5-05-04: Intraductal delivery of RNAi-based therapeutics to gene targets identified through computational systems modeling (2012) (0)
Theta and Mira at Argonne National Laboratory (2019) (0)
Systems biology: From identifying toxicity pathways to therapeutic engineering (2008) (0)
35 innovators under 35 2013 (2013) (0)
C. elegans models of Alzheimer's disease and Parkinson's disease: Systems biology identifies an interaction between tau and LRRK2 (2010) (0)
Q&A: Circuit capacity (2012) (0)
Erratum: Deconstructing transcriptional heterogeneity in pluripotent stem cells (2015) (0)
Forward engineering. Interview by Kristie Nybo. (2012) (0)
Review: What is Life? by Ed Regis (2008) (0)
CRISPR-based genomic tools for the manipulation of genetically intractable microorganisms (2018) (0)
A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria (2019) (0)
Synthetic genetic circuits to uncover and enforce the OCT4 trajectories of successful reprogramming of human fibroblasts (2023) (0)
Author Correction: A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (0)
Author Correction: ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors (2019) (0)
A systems biology pipeline identifies regulatory networks for stem cell engineering (2019) (0)
A self-propagating, barcoded transposon system for the dynamic rewiring of genomic networks. (2023) (0)
Controlled continuous evolution of enzymatic activity screened at ultrahigh throughput using drop-based microfluidics. (2023) (0)
Predictive biology: modelling, understanding and harnessing microbial complexity (2020) (0)
Discovering small-molecule senolytics with deep neural networks. (2023) (0)
Publisher Correction: Definitions and guidelines for research on antibiotic persistence (2019) (0)

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