Julian Gough
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Professor of Bioinformatics in the Department of Computer Science at the University of Bristol, UK
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Julian Gough biology Degrees
Biology
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Bioinformatics
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World Rank
#187
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Biology
Why Is Julian Gough Influential?
(Suggest an Edit or Addition)According to Wikipedia, Julian John Thurstan Gough is a Group Leader in the Laboratory of Molecular Biology of the Medical Research Council . He was previously a professor of bioinformatics at the University of Bristol. Education Gough was educated at The Perse School in Cambridge and the University of Bristol where he was awarded a joint honours degree in Mathematics and Physics in 1998. He went on to complete his PhD in the Laboratory of Molecular Biology supervised by Cyrus Chothia on genome analysis and protein structure as a postgraduate student of Sidney Sussex College, Cambridge, graduating in 2001.
Julian Gough 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Transcriptional Landscape of the Mammalian Genome (2005) (3394)
- InterPro: the integrative protein signature database (2008) (1850)
- A promoter-level mammalian expression atlas (2014) (1664)
- Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs (2002) (1543)
- Classification of Intrinsically Disordered Regions and Proteins (2014) (1434)
- InterPro in 2017—beyond protein family and domain annotations (2016) (1217)
- Assignment of homology to genome sequences using a library of hidden Markov models that represent all proteins of known structure. (2001) (1207)
- The InterPro protein families database: the classification resource after 15 years (2014) (1186)
- InterPro in 2019: improving coverage, classification and access to protein sequence annotations (2018) (1101)
- InterPro in 2011: new developments in the family and domain prediction database (2011) (1100)
- Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models (2012) (966)
- The InterPro protein families and domains database: 20 years on (2020) (858)
- A large-scale evaluation of computational protein function prediction (2013) (784)
- An atlas of human long non-coding RNAs with accurate 5′ ends (2017) (783)
- An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man (2010) (592)
- InterPro, progress and status in 2005 (2004) (573)
- New developments in the InterPro database (2007) (542)
- D2P2: database of disordered protein predictions (2012) (531)
- Evolution of the Protein Repertoire (2003) (519)
- Domain combinations in archaeal, eubacterial and eukaryotic proteomes. (2001) (493)
- An integrative approach to predicting the functional effects of non-coding and coding sequence variation (2015) (471)
- The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line (2009) (441)
- SUPERFAMILY—sophisticated comparative genomics, data mining, visualization and phylogeny (2008) (404)
- The genome of Aiptasia, a sea anemone model for coral symbiosis (2015) (320)
- An expanded evaluation of protein function prediction methods shows an improvement in accuracy (2016) (316)
- A Database of Bacterial Lipoproteins (DOLOP) with Functional Assignments to Predicted Lipoproteins (2006) (287)
- SUPERFAMILY: HMMs representing all proteins of known structure. SCOP sequence searches, alignments and genome assignments (2002) (282)
- The SUPERFAMILY database in 2004: additions and improvements (2004) (259)
- The SUPERFAMILY database in 2007: families and functions (2006) (237)
- A predictive computational framework for direct reprogramming between human cell types (2016) (234)
- The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens (2019) (219)
- Predicting the functional consequences of cancer-associated amino acid substitutions (2013) (208)
- A phylogenomic profile of globins (2006) (205)
- Transcript Annotation in FANTOM3: Mouse Gene Catalog Based on Physical cDNAs (2006) (189)
- Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor (2003) (182)
- Supra-domains: evolutionary units larger than single protein domains. (2004) (176)
- SUPERFAMILY 1.75 including a domain-centric gene ontology method (2010) (169)
- An Atlas of Combinatorial Transcriptional Regulation in Mouse and Man (2010) (165)
- Distinguishing Protein-Coding from Non-Coding RNAs through Support Vector Machines (2006) (164)
- A comparison of profile hidden Markov model procedures for remote homology detection. (2002) (164)
- Ranking non-synonymous single nucleotide polymorphisms based on disease concepts (2014) (159)
- Three globin lineages belonging to two structural classes in genomes from the three kingdoms of life. (2005) (157)
- Convergent evolution of domain architectures (is rare) (2005) (157)
- The SCOP database in 2020: expanded classification of representative family and superfamily domains of known protein structures (2019) (148)
- Sequential transcriptional changes dictate safe and effective antigen-specific immunotherapy (2014) (143)
- An insight into domain combinations (2001) (123)
- Classification, expression pattern, and E3 ligase activity assay of rice U-box-containing proteins. (2008) (122)
- The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli. (2001) (116)
- Genomic and structural aspects of protein evolution. (2009) (110)
- Mouse proteome analysis. (2003) (103)
- dcGO: database of domain-centric ontologies on functions, phenotypes, diseases and more (2012) (101)
- The SUPERFAMILY 2.0 database: a significant proteome update and a new webserver (2018) (95)
- Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals (2016) (91)
- Structured and disordered facets of the GPCR fold. (2014) (73)
- InterPro in 2022 (2022) (73)
- The evolution and structure prediction of coiled coils across all genomes. (2010) (72)
- The SUPERFAMILY 1.75 database in 2014: a doubling of data (2014) (69)
- The ‘dnet’ approach promotes emerging research on cancer patient survival (2014) (69)
- Small-molecule metabolism: an enzyme mosaic. (2001) (63)
- Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains (2012) (61)
- Hologenome analysis of two marine sponges with different microbiomes (2016) (55)
- A daily-updated tree of (sequenced) life as a reference for genome research (2013) (49)
- The SUPERFAMILY database in structural genomics. (2002) (49)
- Currents in Computational Molecular Biology (2000) (47)
- A domain-centric solution to functional genomics via dcGO Predictor (2013) (45)
- Genome3D: exploiting structure to help users understand their sequences (2014) (45)
- Are viruses a source of new protein folds for organisms? – Virosphere structure space and evolution (2011) (40)
- Molecular Principles of Gene Fusion Mediated Rewiring of Protein Interaction Networks in Cancer (2016) (40)
- A Subset of Ubiquitin-Conjugating Enzymes Is Essential for Plant Immunity1[OPEN] (2016) (39)
- Development and evaluation of an automated annotation pipeline and cDNA annotation system. (2003) (39)
- supraHex: An R/Bioconductor package for tabular omics data analysis using a supra-hexagonal map (2014) (37)
- Improving protein secondary structure prediction using a simple k-mer model (2010) (36)
- The linked conservation of structure and function in a family of high diversity: the monomeric cupredoxins. (2004) (36)
- Evolution of the Calcium-Based Intracellular Signaling System (2016) (34)
- TreeVector: Scalable, Interactive, Phylogenetic Trees for the Web (2010) (34)
- Comparison of the small molecule metabolic enzymes of Escherichia coli and Saccharomyces cerevisiae. (2002) (26)
- Genomic scale sub-family assignment of protein domains (2006) (26)
- Short- and Long-Term Effects of UVA on Arabidopsis Are Mediated by a Novel cGMP Phosphodiesterase (2019) (23)
- Sequences and topology: intrinsic disorder in the evolving universe of protein structure. (2011) (21)
- Evolutionarily consistent families in SCOP: sequence, structure and function (2012) (19)
- Expression and in silico structural analysis of a rice (Oryza sativa) hemoglobin 5. (2008) (18)
- Splice junctions are constrained by protein disorder (2015) (17)
- The evolutionary dynamics of protein networks (2010) (17)
- The Evolution of Human Cells in Terms of Protein Innovation (2014) (16)
- Did Viruses Evolve As a Distinct Supergroup from Common Ancestors of Cells? (2016) (16)
- DGEclust: differential expression analysis of clustered count data (2014) (15)
- InterPro in 2011: new developments in the family and domain prediction database (2012) (14)
- Computational methods for direct cell conversion (2016) (12)
- The evolution and structure prediction of coiled coils across all genomes (2010) (11)
- Genome3D: integrating a collaborative data pipeline to expand the depth and breadth of consensus protein structure annotation (2019) (11)
- Matching phenotypes to whole genomes: Lessons learned from four iterations of the personal genome project community challenges (2017) (11)
- Optimal Hidden Markov Models for All Sequences of Known Structure (2000) (11)
- Proteins with Class α/β Fold Have High-level Participation in Fusion Events (2002) (10)
- CAGI SickKids challenges: Assessment of phenotype and variant predictions derived from clinical and genomic data of children with undiagnosed diseases (2019) (10)
- Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI (2017) (10)
- Evolution of eukaryotic genome architecture: Insights from the study of a rapidly evolving metazoan, Oikopleura dioica (2011) (9)
- A disease-drug-phenotype matrix inferred by walking on a functional domain network. (2013) (9)
- Three reasons protein disorder analysis makes more sense in the light of collagen (2016) (8)
- ‘Why genes in pieces?’—revisited (2019) (8)
- A proteome quality index. (2015) (6)
- Function-selective domain architecture plasticity potentials in eukaryotic genome evolution (2015) (5)
- Sequences and topology: disorder, modularity, and post/pre translation modification. (2013) (5)
- A survey of direct-to-consumer genotype data, and quality control tool (GenomePrep) for research (2021) (5)
- Proteins with class alpha/beta fold have high-level participation in fusion events. (2002) (4)
- Transcript annotation in FANTOM 3 (2006) (3)
- Performance of in silico tools for the evaluation of p 16 INK 4 a ( CDKN 2 A ) variants in CAGI (2017) (3)
- The Genome3D Consortium for Structural Annotations of Selected Model Organisms. (2020) (2)
- Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2021) (2)
- Molecular Interaction Networks to Select Factors for Cell Conversion. (2019) (2)
- Non-Parametric Bayesian Modelling of Digital Gene Expression Data (2013) (1)
- Hypothesis-free phenotype prediction within a genetics-first framework (2023) (1)
- DGEclust: differential expression analysis of clustered count data (2015) (1)
- Correction to: Molecular Interaction Networks to Select Factors for Cell Conversion. (2019) (0)
- The dcGO domain-centric ontology database in 2023: new website and extended annotations for protein structural domains. (2023) (0)
- The Darwinian tree of life in light of horizontal gene transfer (is still sound) (2011) (0)
- sTOL: a daily-updated species tree of (sequenced) life as a reference to analyze genomic data (2012) (0)
- The `dnet’ approach promotes emerging research on cancer patient survival (2014) (0)
- Hologenome analysis of two marine sponges with different microbiomes (2016) (0)
- Effects of UVA on Arabidopsis Are Mediated by a Novel cGMP (0)
- 'Why genes in pieces?'-revisited. Nucleic Acids (2019) (0)
- Sequence, structure and function evolution at the SCOP family level (2010) (0)
- Automated Function Prediction Featuring a Critical Assessment of Function Annotations (2011) (0)
- Genomics update A Proteome Quality Index (2014) (0)
- How many new genes are there (2006) (0)
- The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens (2019) (0)
- A domain-centric solution to functional genomics via dcGO Predictor (2013) (0)
- In grateful recognition of our Editorial Board (2016) (0)
- Ranking non-synonymous single nucleotide polymorphisms based on disease concepts (2014) (0)
- Horizontal gene transfer of protein domain architectures (2011) (0)
- Author Correction: Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network (2022) (0)
- Structural Annotations of Genomes with Superfamily and G3D (2013) (0)
- Proteins with alpha/beta Fold Class Have High Participation in Fusion Events (2002) (0)
- Open-source R packages for omics data integrative analysis and visualisation (2014) (0)
- An exhaustive search for the inositol 1,4,5-triphosphate receptor protein in plants (2011) (0)
- A community resource for analysis and understanding of intrinsic disorder in proteins of fully sequenced genomes (2012) (0)
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