Stephan Ripke
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Stephan Ripke's Degrees
- Bachelors Biology University of Oxford
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Why Is Stephan Ripke Influential?
(Suggest an Edit or Addition)According to Wikipedia, Stephan Ripke is a German statistical geneticist and Research Scientist in the Analytic and Translational Genetics Unit at Massachusetts General Hospital. He is also affiliated with the Broad Institute. He is a leader of the Statistical Analysis Group of the Psychiatric Genomics Consortium. He earned his Ph.D. cum laude from Utrecht University in 2014. He received the Sidney R. Baer, Jr., Prize for Innovative and Promising Schizophrenia Research from the Brain & Behavior Research Foundation in 2014, and was awarded a Young Investigator Grant from them in 2015.
Stephan Ripke's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014) (6445)
- Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease (2012) (4007)
- Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies (2014) (3142)
- Genetic effects on gene expression across human tissues (2017) (2841)
- Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis (2013) (2439)
- Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs (2013) (2011)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression (2018) (1816)
- Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
- GenABEL: an R library for genome-wide association analysis (2007) (1781)
- Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations (2015) (1712)
- Genome-wide association study identifies five new schizophrenia loci (2011) (1680)
- Partitioning heritability by functional annotation using genome-wide association summary statistics (2015) (1615)
- Genome-wide Association Analysis Identifies 14 New Risk Loci for Schizophrenia (2013) (1455)
- Analysis of shared heritability in common disorders of the brain (2016) (1385)
- Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder (2018) (1248)
- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk (2019) (1232)
- Identification of common genetic risk variants for autism spectrum disorder (2019) (1140)
- The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation (2010) (1129)
- A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects: CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (2016) (1125)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2018) (1124)
- Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions (2018) (1090)
- Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism (2018) (1064)
- Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder (2017) (998)
- Most genetic risk for autism resides with common variation (2014) (995)
- A mega-analysis of genome-wide association studies for major depressive disorder (2013) (979)
- Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 (2011) (929)
- Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment (2020) (894)
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. (2015) (858)
- Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease (2011) (747)
- Seven New Loci Associated with Age-Related Macular Degeneration (2013) (741)
- Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects (2016) (736)
- Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders (2019) (724)
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence (2018) (705)
- Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways (2015) (676)
- Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions (2007) (657)
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (2012) (599)
- Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries (2012) (543)
- Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes (2017) (517)
- Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. (2014) (510)
- Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder. (2010) (459)
- Mapping the human genetic architecture of COVID-19 (2021) (455)
- Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned (2010) (430)
- Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC) (2010) (426)
- Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico (2013) (419)
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia (2022) (361)
- Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia (2018) (359)
- Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa. (2017) (357)
- Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders (2016) (351)
- Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population (2015) (343)
- Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia (2017) (341)
- Polymorphisms in the Drug Transporter Gene ABCB1 Predict Antidepressant Treatment Response in Depression (2008) (341)
- Comparative genetic architectures of schizophrenia in East Asian and European populations (2018) (329)
- Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability (2017) (328)
- Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia (2013) (325)
- Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa (2019) (314)
- Mapping genomic loci prioritises genes and implicates synaptic biology in schizophrenia (2020) (308)
- A rare penetrant mutation in CFH confers high risk of age-related macular degeneration (2011) (305)
- Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia (2017) (301)
- A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. (2009) (297)
- Revealing the complex genetic architecture of obsessive–compulsive disorder using meta-analysis (2018) (294)
- Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate (2013) (275)
- PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome (2008) (269)
- Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration (2011) (264)
- International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci (2019) (258)
- High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis (2014) (250)
- High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis (2014) (250)
- Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders (2013) (248)
- Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology (2021) (240)
- Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder (2012) (232)
- Discovery of the first genome-wide significant risk loci for ADHD (2017) (229)
- Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis. (2015) (224)
- Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. (2013) (219)
- The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression (2009) (211)
- A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (2021) (207)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder (2015) (206)
- Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19 (2020) (205)
- Genome-wide meta-analysis in alopecia areata resolves HLA associations and reveals two new susceptibility loci (2015) (199)
- Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof-of-concept and roadmap for future studies (2016) (198)
- Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium☆ (2017) (183)
- Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci (2014) (174)
- A direct test of the diathesis–stress model for depression (2017) (172)
- Case-control genome-wide association study of attention-deficit/hyperactivity disorder. (2010) (168)
- RICOPILI: Rapid Imputation for COnsortias PIpeLIne (2019) (157)
- Genetic Studies of Major Depressive Disorder: Why Are There No Genome-wide Association Study Findings and What Can We Do About It? (2014) (156)
- Copy number variation in bipolar disorder (2015) (154)
- Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers. (2016) (149)
- TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies (2011) (145)
- GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. (2019) (144)
- Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls (2013) (143)
- Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles (2014) (141)
- IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations (2008) (140)
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes (2018) (139)
- High Loading of Polygenic Risk for ADHD in Children With Comorbid Aggression (2013) (137)
- Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis. (2013) (136)
- A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder (2017) (136)
- Association Study of Common Genetic Variants and HIV-1 Acquisition in 6,300 Infected Cases and 7,200 Controls (2013) (133)
- Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia (2017) (129)
- Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients (2020) (119)
- Improving genetic prediction by leveraging genetic correlations among human diseases and traits (2018) (118)
- Runs of Homozygosity Implicate Autozygosity as a Schizophrenia Risk Factor (2012) (117)
- Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores (2015) (116)
- Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. (2012) (115)
- ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties (2017) (112)
- A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy. (2014) (112)
- The genetic association between personality and major depression or bipolar disorder. A polygenic score analysis using genome-wide association data (2011) (111)
- Genetic correlation between amyotrophic lateral sclerosis and schizophrenia (2017) (107)
- Exploring the genetics of irritable bowel syndrome: a GWA study in the general population and replication in multinational case-control cohorts (2013) (106)
- Common risk variants identified in autism spectrum disorder (2017) (106)
- Genetic Schizophrenia Risk Variants Jointly Modulate Total Brain and White Matter Volume (2013) (106)
- Rare, low-frequency, and common variants in the protein-coding sequence of biological candidate genes from GWASs contribute to risk of rheumatoid arthritis. (2013) (104)
- Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021) (104)
- Specific glial functions contribute to schizophrenia susceptibility. (2014) (100)
- Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients (2014) (100)
- Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis (2017) (100)
- The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls (2018) (99)
- Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders (2015) (95)
- Estimation of SNP heritability from dense genotype data. (2013) (94)
- Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction. (2013) (93)
- Evidence of Common Genetic Overlap Between Schizophrenia and Cognition (2015) (92)
- Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease (2009) (92)
- Complement genes contribute sex-biased vulnerability in diverse illnesses (2020) (92)
- An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype (2017) (89)
- Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium (2017) (87)
- Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 (2021) (86)
- Converging Genetic and Functional Brain Imaging Evidence Links Neuronal Excitability to Working Memory, Psychiatric Disease, and Brain Activity (2014) (86)
- Heritability and genome-wide association study to assess genetic differences between advanced age-related macular degeneration subtypes. (2012) (81)
- Genetic Variation in Soluble Epoxide Hydrolase (EPHX2) Is Associated With an Increased Risk of Ischemic Stroke in White Europeans (2008) (78)
- Temporal delay discounting in acutely ill and weight-recovered patients with anorexia nervosa (2015) (78)
- Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (2019) (72)
- Local genetic effects on gene expression across 44 human tissues (2016) (72)
- Investigation of the Genetic Association between Quantitative Measures of Psychosis and Schizophrenia: A Polygenic Risk Score Analysis (2012) (71)
- Rare Copy Number Variation in Treatment-Resistant Major Depressive Disorder (2014) (69)
- Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans. (2012) (67)
- Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors (2020) (66)
- Genome-wide Analysis of Insomnia Disorder (2018) (66)
- Partitioning heritability by functional category using GWAS summary statistics (2015) (66)
- Genome-wide association study of multiplex schizophrenia pedigrees. (2012) (66)
- Reward processing and intertemporal decision making in adults and adolescents: The role of impulsivity and decision consistency (2012) (65)
- Common alleles contribute to schizophrenia in CNV carriers (2015) (65)
- Genetic effects influencing risk for major depressive disorder in China and Europe (2017) (62)
- A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts (2020) (60)
- New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. (2015) (58)
- High loading of polygenic risk in cases with chronic schizophrenia (2016) (58)
- The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders (2008) (58)
- Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes. (2016) (56)
- Altered reward processing in adolescents with prenatal exposure to maternal cigarette smoking. (2013) (56)
- The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects (2015) (55)
- Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia (2014) (53)
- Genome-Wide Association Study of Intracranial Aneurysm Identifies a New Association on Chromosome 7 (2014) (53)
- Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia (2016) (53)
- Associations of CFHR1–CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent (2010) (53)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection (2016) (50)
- Altered Neural Efficiency of Decision Making During Temporal Reward Discounting in Anorexia Nervosa. (2016) (47)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depressive disorder (2017) (47)
- A Genome-wide Association Analysis of a Broad Psychosis Phenotype Identifies Three Loci for Further Investigation (2014) (46)
- Genome‐wide gene‐environment interaction in depression: A systematic evaluation of candidate genes (2018) (46)
- Genomewide association studies of suicide attempts in US soldiers (2017) (45)
- Schizophrenia genetic variants are not associated with intelligence (2013) (44)
- Acute and chronic nicotine effects on behaviour and brain activation during intertemporal decision making (2014) (44)
- A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes (2017) (43)
- Genetic meta-analysis identifies 9 novel loci and functional pathways for Alzheimer’s disease risk (2018) (41)
- Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability? (2018) (40)
- Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs (2012) (40)
- An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases. (2014) (40)
- Genome-wide meta-analysis of depression in 807,553 individuals identifies 102 independent variants with replication in a further 1,507,153 individuals (2018) (40)
- Association of polygenic score for major depression with response to lithium in patients with bipolar disorder (2020) (37)
- Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms (2016) (37)
- The Genetic Architecture of Depression in Individuals of East Asian Ancestry (2021) (37)
- Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches (2019) (37)
- Functional neuroimaging effects of recently discovered genetic risk loci for schizophrenia and polygenic risk profile in five RDoC subdomains (2017) (37)
- Polymorphisms in the GAD2 gene‐region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders (2009) (36)
- Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01 (2021) (36)
- Reliability in adolescent fMRI within two years – a comparison of three tasks (2017) (36)
- Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia (2015) (36)
- Polymorphisms in the angiotensin‐converting enzyme gene region predict coping styles in healthy adults and depressed patients (2009) (35)
- Genetic risk variants for social anxiety (2017) (35)
- Largest GWAS (N=1,126,563) of Alzheimer's Disease Implicates Microglia and Immune Cells (2020) (32)
- Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels (2013) (32)
- Genome‐wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness (2016) (32)
- A polygenic resilience score moderates the genetic risk for schizophrenia (2019) (31)
- GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence (2017) (31)
- The IMAGEN study: a decade of imaging genetics in adolescents (2020) (31)
- Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation. (2008) (29)
- Gene–gene and gene–environment interactions in ulcerative colitis (2014) (29)
- Genome‐wide analyses of psychological resilience in U.S. Army soldiers (2019) (27)
- Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression (2019) (27)
- Quantifying between‐cohort and between‐sex genetic heterogeneity in major depressive disorder (2019) (26)
- No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. (2014) (26)
- Erratum: Common alleles contribute to schizophrenia in CNV carriers (2015) (26)
- Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2021) (26)
- Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2018) (25)
- Complement genes contribute sex-biased vulnerability in diverse disorders (2020) (25)
- A Novel Approach to Detect Cumulative Genetic Effects and Genetic Interactions in Crohn’s Disease (2013) (24)
- Amygdala-function perturbations in healthy mid-adolescents with familial liability for depression. (2014) (24)
- Genetic comorbidity between major depression and cardio-metabolic disease, stratified by age at onset of major depression (2019) (24)
- Theory of mind network activity is altered in subjects with familial liability for schizophrenia. (2016) (23)
- Haplotypes of common SNPs can explain missing heritability of complex diseases (2015) (23)
- Genome-wide association study identifies 30 loci associated with bipolar disorder (2019) (22)
- Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways (2018) (22)
- Bipolar polygenic loading and bipolar spectrum features in major depressive disorder (2014) (22)
- Genetic Variation in the Lymphotoxin-Alpha Pathway and the Risk of Ischemic Stroke in European Populations (2009) (22)
- Regulatory variants explain much more heritability than coding variants across 11 common diseases (2014) (22)
- Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression (2010) (22)
- Neural Correlates of Failed Inhibitory Control as an Early Marker of Disordered Eating in Adolescents (2019) (21)
- Response to ‘Predicting the diagnosis of autism spectrum disorder using gene pathway analysis' (2013) (21)
- Migraine polygenic risk score associates with efficacy of migraine-specific drugs (2019) (21)
- Pavlovian-To-Instrumental Transfer and Alcohol Consumption in Young Male Social Drinkers: Behavioral, Neural and Polygenic Correlates (2019) (21)
- Shared Genetic Risk Factors of Intracranial, Abdominal, and Thoracic Aneurysms (2016) (20)
- Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression (2020) (20)
- A recessive genetic model and runs of homozygosity in major depressive disorder (2014) (20)
- Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression (2020) (20)
- Disentangling polygenic associations between attention-deficit/hyperactivity disorder, educational attainment, literacy and language (2019) (20)
- Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies (2019) (20)
- Identifying the Common Genetic Basis of Antidepressant Response (2021) (19)
- Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study (2018) (19)
- Shared genetic etiology between alcohol dependence and major depressive disorder (2018) (19)
- Cortical Surfaces Mediate the Relationship Between Polygenic Scores for Intelligence and General Intelligence. (2019) (19)
- Subtle stratification confounds estimates of heritability from rare variants (2016) (18)
- Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank (2019) (18)
- A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies. (2016) (17)
- Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression (2010) (17)
- Mid-adolescent neurocognitive development of ignoring and attending emotional stimuli (2015) (17)
- Common Neural Correlates of Intertemporal Choices and Intelligence in Adolescents (2014) (16)
- Low Smoking Exposure, the Adolescent Brain, and the Modulating Role of CHRNA5 Polymorphisms. (2019) (16)
- Erratum: Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia (2016) (16)
- Interindividual Differences in Mid-Adolescents in Error Monitoring and Post-Error Adjustment (2014) (15)
- Identification of increased genetic risk scores for schizophrenia in treatment-resistant patients (2015) (15)
- Neural Correlates of Adolescent Irritability and Its Comorbidity With Psychiatric Disorders. (2020) (14)
- Genome-wide association study of pediatric obsessive-compulsive traits: shared genetic risk between traits and disorder (2019) (14)
- Genetic risk variants for social anxiety (2017) (14)
- Erratum: Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia (2017) (13)
- Corrigendum: Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia (Molecular Psychiatry (2017) 22 (1502-1508) DOI: 10.1038/mp.2016.97) (2018) (13)
- New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations (2021) (13)
- Detailed stratified GWAS analysis for severe COVID-19 in four European populations (2022) (13)
- Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information (2021) (12)
- Polygenic risk for schizophrenia and schizotypal traits in non-clinical subjects. (2020) (11)
- Antidepressant Response in Major Depressive Disorder: A Genome-wide Association Study (2020) (11)
- Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism (2008) (10)
- Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2019) (10)
- Genome-wide Association Study of Clinical Features in the Schizophrenia Psychiatric Genomics Consortium: Confirmation of Polygenic Effect on Negative Symptoms (2017) (9)
- Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting (2021) (9)
- A genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression (2009) (9)
- Differential predictors for alcohol use in adolescents as a function of familial risk (2021) (8)
- Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk (2020) (8)
- Exploring adolescent cognitive control in a combined interference switching task (2014) (7)
- Genome-wide association study identifies new locus associated with OCD (2021) (7)
- Characterisation of age and polarity at onset in bipolar disorder (2021) (7)
- Current Status of Schizophrenia Gwas (2017) (7)
- Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorders (2022) (6)
- Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores (2018) (6)
- Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium. (2021) (6)
- Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate (2015) (6)
- Psychological trauma and the genetic overlap between posttraumatic stress disorder and major depressive disorder (2020) (5)
- T36 Genome-Wide Association Study Of Borderline Personality Disorder Reveals Genetic Overlap With Bipolar Disorder And Schizophrenia (2017) (5)
- Insights From Genome-Wide Association Studies (GWAS) (2016) (5)
- 44 A DIRECT TEST OF THE DIATHESIS-STRESS MODEL FOR DEPRESSION (2019) (4)
- Erratum to: Genetic risk variants for social anxiety (American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, (2017), 174, 2, (120-131), 10.1002/ajmg.b.32520) (2017) (4)
- Effects of a neurodevelopmental genes based polygenic risk score for schizophrenia and single gene variants on brain structure in non-clinical subjects: A preliminary report (2019) (4)
- A Model Integrating Genetic and Environmental Factors Interactions Can Predict Crohn’s Disease Risk: 1701 (2014) (4)
- Intranasal oxytocin administration impacts the acquisition and consolidation of trauma-associated memories: a double-blind randomized placebo-controlled experimental study in healthy women (2021) (4)
- Statistical and functional convergence of common and rare genetic influences on autism at chromosome 16p (2022) (4)
- Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder (2021) (3)
- 223. Genome-Wide Association Study of Posttraumatic Stress Disorder Symptom Domains in Two Cohorts of United States Army Soldiers (2017) (3)
- Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness (2021) (3)
- Association of a brain methylation site with clinical outcomes in depression does not replicate across populations. (2015) (3)
- Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation (2018) (3)
- 162 Genetics, Serologies, and Smoking Predict Highly Morbid Crohn's Disease in Erroneously Diagnosed UC Patients (2012) (3)
- 57 PGC SCZ WORKGROUP: GWAS WITH OVER 70.000 CASES AND 100,000 CONTROLS (2019) (3)
- Genetic overlap between Attention-Deficit / Hyperactivity Disorder and Bipolar Disorder : Evidence from GWAS meta-analysis (2017) (3)
- Common Genetic Variation and Age of Onset of Anorexia Nervosa (2021) (3)
- Nucleus accumbens connectivity at rest is associated with alcohol consumption in young male adults (2019) (3)
- A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank (2020) (3)
- Genomewide Analyses of Psychological Resilience in US Army Soldiers (2019) (3)
- 14GENETIC META-ANALYSIS IDENTIFIES 9 NOVEL LOCI AND FUNCTIONAL PATHWAYS FOR ALZHEIMER'S DISEASE RISK (2019) (3)
- Whole genome analysis reveals new potential drug targets as predictors of antidepressant treatment response (2007) (2)
- Genetic variation in the lymphotoxin alpha pathway and the risk of ischaemic stroke (2007) (2)
- Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients (2007) (2)
- Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (2)
- Genetic variation in the Major Histocompatibility Complex and association with depression (2018) (2)
- Comparative genetic architectures of schizophrenia in East Asian and European populations (2019) (2)
- Potential Genetic Overlap Between Insomnia and Sleep Symptoms in Major Depressive Disorder: A Polygenic Risk Score Analysis (2021) (2)
- Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (2022) (2)
- The Relationship of Attention-Deficit/Hyperactivity Disorder With Posttraumatic Stress Disorder: A Two-Sample Mendelian Randomization and Population-Based Sibling Comparison Study (2022) (2)
- Genome-Wide Association Study of Panic Disorder (2019) (2)
- TH50. GENOME-WIDE ASSOCIATION STUDY OF BORDERLINE PERSONALITY DISORDER – FIRST RESULTS FROM THE INTERNATIONAL BORDERLINE GENOMICS CONSORTIUM (2021) (1)
- Statistical genetics : genome-wide studies (2018) (1)
- Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk (2020) (1)
- Genome-wide association study of coronary and aortic calci fi cation implicates risk loci for coronary artery disease and myocardial infarction (1)
- Increasing sample diversity in psychiatric genetics – Introducing a new cohort of patients with schizophrenia and controls from Vietnam – Results from a pilot study (2021) (1)
- Correction: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank (2020) (1)
- Genome-Wide Association Study of Panic Disorder (2017) (1)
- Exploring the Overlap Between Alopecia Areata and Major Depressive Disorder: Epidemiological and Genetic Perspectives. (2023) (1)
- Ricopili Pipeline And Standards of GWAS Analyses (2019) (1)
- Heritability of Alcohol Use Disorder: Evidence from Twin Studies and Genome-Wide Association Studies (2020) (1)
- Study protocol of the Berlin Research Initiative for Diagnostics, Genetics and Environmental Factors in Schizophrenia (BRIDGE-S) (2023) (1)
- Non-random mating, parent-of-origin, and maternal–fetal incompatibility effects in schizophrenia (2013) (1)
- Hair Cortisol in Twins: Heritability and Genetic Overlap with Psychological Variables and Stress-System Genes (2017) (1)
- GWAS results for educational attainment aid in identifying genetic heterogeneity of schizophrenia (2017) (1)
- Associations of delay discounting and drinking trajectories from ages 14 to 22. (2022) (1)
- Genome-wide association analyses of symptom severity among clozapine-treated patients with schizophrenia spectrum disorder (2021) (1)
- The Relationship Between the Recognition of Basic Emotions and Negative Symptoms in Individuals With Schizophrenia Spectrum Disorders – An Exploratory Study (2022) (1)
- Multi-ancestry GWAS of major depression aids locus discovery, fine-mapping, gene prioritisation, and causal inference (2022) (1)
- Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (2021) (1)
- Genome-wide association for major depression through age at onset stratificationGenomic analysis of age at onset in depression (2016) (1)
- Associations of CFHR 1 – CFHR 3 deletion and a CFH snp to age-related macular degeneration (2010) (1)
- How alcohol makes the epigenetic clock tick faster and the clock reversing effect of abstinence (2022) (1)
- T54 Beps - Berlin Psychosis Study (2017) (1)
- Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans. (2022) (1)
- Characterization of Age and Polarity at Onset in Bipolar Disorder (2021) (1)
- T22INVESTIGATION OF PATHWAY-BASED POLYGENIC RISK SCORES USING MACHINE LEARNING PREDICTION AND CLASSIFICATION SCHEMES (2019) (1)
- Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa (2019) (0)
- Identification of common genetic risk variants for autism spectrum disorder (2019) (0)
- W69. POLYGENIC PREDICTORS OF TREATMENT OUTCOME FOLLOWING LITHIUM AUGMENTATION IN MAJOR DEPRESSION (2021) (0)
- 46. PATHWAY-BASED POLYGENIC RISK SCORES USING MACHINE LEARNING: APPLICATION TO SCHIZOPHRENIA AND BIPOLAR DISORDER (2022) (0)
- VKučinskas-2001-2016 (2016) (0)
- 36. The Effect of Oxytocin in Combination With a Mindfulness-Based Group Therapy on Negative Symptoms, Empathy, Affect and Stress in Individuals With a Schizophrenia Spectrum Disorder – Results: of a Pilot Study (2023) (0)
- 39GENOME-WIDE ASSOCIATION STUDY IDENTIFIES NOVEL LOCI ASSOCIATED WITH BIPOLAR DISORDER (2019) (0)
- GWAS meta-analysis (N=279,930) identifies new genes and functional links to general cognitive ability (2018) (0)
- Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia (2018) (0)
- Decision and Reward in Intertemporal Choice: The Roles of Brain Development, Inter-individual Differences and Pharmacological Influences (2013) (0)
- F51. Putative Causal Relationship Among Polygenic Scores, Cortical Surfaces, and General Intelligence (2019) (0)
- T64 Genome-Wide Association Study Of Posttraumatic Stress Disorder Symptoms In Two Cohorts Of United States Army Soldiers (2017) (0)
- P.3.10 Glutamate and interleukin receptor genes are associated with antidepressant treatment emergent suicidal ideation (2008) (0)
- Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder (2018) (0)
- Combined association analysis experiment for major depressive disorder (2011) (0)
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence (2018) (0)
- Genome-wide meta-analysis identifies new loci and functional pathways influencing 1 Alzheimer ’ s disease risk 2 3 (2020) (0)
- An accurate and reproducible discrimination tool for inflammatory bowel disease subtype using genetics, serologies, and smoking status: O-2. (2011) (0)
- Pharmacogenetics of antidepressant treatment outcome - Results from a genome-wide multilocus analysis including clinical predictors (2009) (0)
- M28 Polygenic Risk For BIP, MDD, And SCZ In Andalusian Multiplex Families (2017) (0)
- Reliability in adolescent fMRI within two years – a comparison of three tasks (2017) (0)
- 38. The Relationship Between the Recognition of Emotions and Negative Symptoms in Individuals With a Schizophrenia Spectrum Disorder (2023) (0)
- Oxytocin vs. placebo effects on intrusive memory consolidation using a trauma film paradigm: a randomized, controlled experimental study in healthy women (2023) (0)
- Polymorphisms in metabotropic glutamate receptor 1 are associated with major depressive disorder (2008) (0)
- Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder (2018) (0)
- The relationship between the recognition of specific basic emotions and negative symptom domains in patients with schizophrenia spectrum disorders (2022) (0)
- Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions (2019) (0)
- Genetics of educational attainment aid in identifying biological subcategories of schizophrenia (2017) (0)
- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk (2019) (0)
- DNAJC13 influences responses of the extended reward system to conditioned stimuli: a genome-wide association study (2022) (0)
- A method to exploit the structure of genetic ancestry space to enhance case-control studies (2016) (0)
- 1 Analysis of Shared Heritability in Common Disorders of the Brain 1 (2017) (0)
- Polymorphisms in tryptophan hydroxylase 2 leading to decreased serotonergic activity contribute to elevated risk for metabolic syndrome in depression (2009) (0)
- TH20. PATHWAY-BASED POLYGENIC RISK SCORES USING MACHINE LEARNING CLASSIFICATION SCHEMES: APPLICATION TO BIPOLAR DISORDER (2021) (0)
- Sequence variation in the gene encoding soluble epoxide hydrolase (EPHX2) is associated with increased susceptibility to ischemic stroke in a central european population (2007) (0)
- 62 GENOME-WIDE CROSS-DISORDER ANALYSES OF SCHIZOPHRENIA AND ALCOHOL USE DISORDER IN MORE THAN 350,000 INDIVIDUALS REVEAL SCHIZOPHRENIA'S GENETIC OVERLAP WITH DISORDERED DRINKING BUT NOT DRINKS PER WEEK (2019) (0)
- Epilepsies, IMSGC consortium, IPDGC consortium, METASTROKE and Intracerebral Hemorrhage Studies of the International Stroke Genetics Consortium, Attention-Deficit Hyperactivity Disorder Working Group of the Psychiatric Genomics Consortium, Anorexia Nervosa Working Group of the Psychiatric Genomics C (2016) (0)
- Evidence for a shared genetic contribution to loneliness and Borderline Personality Disorder (2023) (0)
- M63 Genome Wide Association Results of Alcoholic Use Disorder Patients And Healthy Controls (2017) (0)
- High density mapping of the MHC reveals a common role for HLA- DRB1*01:03 in IBD and heterozygous advantage in ulcerative colitis (2014) (0)
- 13. DISTINGUISHING DIFFERENT PSYCHIATRIC DISORDERS USING DDX-PRS (2022) (0)
- Migraine polygenic risk score associates with e ffi cacy of migraine-speci fi c drugs (0)
- Gwas Studies in Anxiety Disorders (2017) (0)
- BIROn - Birkbeck Institutional Research Online (2019) (0)
- Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease (2020) (0)
- Genetic effects in fl uencing risk for major depressive disorder in China and Europe (2017) (0)
- Procedure of the interference and switch task with two out of 16 possible stimuli. (2014) (0)
- SNPs in the NTRK2 gene are associated with depressive disorder (2007) (0)
- Edinburgh Research Explorer Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder (2017) (0)
- Erratum (1981) (0)
- 5:15 PM NOVEL GENETIC RISK VARIANTS FOR CLOZAPINE-ASSOCIATED NEUTROPENIA (2014) (0)
- Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (2022) (0)
- Polymorphisms in the leptin gene are associated with resistance to antidepressant treatment and lower cognitive performance in depression (2007) (0)
- Elevated polygenic burden for autism is associated with differential DNA methylation at birth (2018) (0)
- GWAS of major depressive disorder (2011) (0)
- F26“GWAS QUALITY SCORE” (GQS) FOR ASSOCIATED REGIONS IN GWAS META-ANALYSES (2019) (0)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression (2018) (0)
- Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease (2021) (0)
- 5:00 PM DOPAMINE OR GLUTAMATE: USING GENETIC COPY NUMBER VARIANT PATHWAY ANALYSIS AND TREATMENT RESISTANCE TO ADJUDICATE SCHIZOPHRENIA HYPOTHESES (2014) (0)
- Title Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate Permalink (2013) (0)
- Common DNA sequence variation and psychiatric disease (2014) (0)
- No evidence for common genetic variants shared between multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) (2011) (0)
- Su1748 A Novel Approach to Detect Cumulative Genetic Effects and Genetic Interactions in Crohn's Disease (2013) (0)
- Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection (2019) (0)
- Gene–gene and gene–environment interactions in ulcerative colitis (2013) (0)
- SNPs in the NTRK2 gene are associated with age-at-onset of depressive disorder and attempted suicide (2007) (0)
- 1 USING GENETIC DIVERSITY FROM EAST ASIA TO IMPROVE THE BIOLOGICAL INSIGHT INTO SCHIZOPHRENIA (2019) (0)
- Brain response during correct post-error/post-missing trials. (2014) (0)
- Novel Gene-Gene and Gene-Environment Interactions in Ulcerative Colitis: ACG IBD Research Award: 1690 (2013) (0)
- INSIGHTS FROM GENOTYPED-BASED CASE-CASE ANALYSIS OF SCHIZOPHRENIA AND BIPOLAR DISORDER (2022) (0)
- Flowchart for (1) detection and replication of schizophrenia associated pathways and (2) identification of the most informative genes, and (3) functional annotation of single nucleotide polymorphisms in the genes of interest. (2014) (0)
- Susceptibility gene hunting for recurrent unipolar depression using 400k genome-wide genotype data (2007) (0)
- Age at first birth in women is genetically associated with increased risk of schizophrenia (2018) (0)
- SA132THE RELATIONSHIP BETWEEN POLYGENIC RISK SCORES AND G IN PGC2 SCHIZOPHRENIA CASES (2019) (0)
- 45. GENOME-WIDE ASSOCIATION STUDY OF BORDERLINE PERSONALITY DISORDER - AN UPDATE FROM THE INTERNATIONAL BORDERLINE GENOMICS CONSORTIUM (2022) (0)
- Correction: Investigation of the Genetic Association between Quantitative Measures of Psychosis and Schizophrenia: A Polygenic Risk Score Analysis (2013) (0)
- Corrigendum: Potential genetic overlap between insomnia and sleep symptoms in major depressive disorder: A polygenic risk score analysis (2022) (0)
- Genome-wide association analyses identify 44 risk variants and refine the genetic architecture ofmajor depressive disorder (2018) (0)
- Polygenetic risk scores and phenotypic constellations of obsessive-compulsive disorder in clozapine-treated schizophrenia. (2023) (0)
- A signal of polygenic inheritance from low frequency variants in case-control genome wide association studies elucidates genetic architecture of common diseases (2013) (0)
- A genome-wide association study in patients with panic and anxiety disorders (2007) (0)
- O25. Variance in Dopaminergic Markers: A Possible Marker of Individual Differences in IQ? (2018) (0)
- S78SCHIZOPHRENIA GWAS OF YORUBAS IN SOUTHWESTERN NIGERIA (2019) (0)
- Polymorphisms in the gene encoding the neuropeptide galanin are associated with HPA-axis dysregulation and symptome severity in major-depressive- and anxiety-disorder patients (2009) (0)
- Improving genetic prediction by leveraging genetic correlations among human diseases and traits (2018) (0)
- T33. USING GENOMICS TO AID EARLY DIFFERENTIAL DIAGNOSIS BETWEEN BIPOLAR DISORDER AND MAJOR DEPRESSION (2022) (0)
- Evidence of shared genetic influences underlying schizophrenia and alcohol use disorder, but not alcohol consumption (2020) (0)
- Publisher Correction: Gene expression imputation across multiple brain regions provides insights into schizophrenia risk (2019) (0)
- Introducing a psychiatric genetic cohort of schizophrenia patients and controls from Vietnam (2021) (0)
- GWAS quality score for evaluating associated regions in GWAS analyses (2023) (0)
- Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns (2019) (0)
- Autism Sequencing Consortium (ASC) iPSYCH-BROAD Consortium Broad Institute Center for Common Disease Genomics (Broad-CCDG) (2021) (0)
- SA67 A NEURAL SIGNATURE OF MALLEABILITY: GENERAL INTELLIGENCE CORRELATES WITH VENTRAL STRIATAL ACTIVATION AND EPIGENETIC MARKERS OF DOPAMINE NEUROTRANSMISSION (2019) (0)
- 88. INSIGHTS OFFERED BY CONDITIONAL ANALYSIS AND HLA/C4 TYPE IMPUTATION ON SCHIZOPHRENIA GENOMICS (2022) (0)
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes (2018) (0)
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