George Davis Snell

About

From Wikipedia

George Davis Snell was an American mouse geneticist and basic transplant immunologist.Work George Snell shared the 1980 Nobel Prize in Physiology or Medicine with Baruj Benacerraf and Jean Dausset for their discoveries concerning "genetically determined structures on the cell surface that regulate immunological reactions". Snell specifically "discovered the genetic factors that determine the possibilities of transplanting tissue from one individual to another. It was Snell who introduced the concept of H antigens." Snell's work in mice led to the discovery of HLA, the major histocompatibility complex, in humans that is analogous to the H-2 complex in mice. Recognition of these key genes was prerequisite to successful tissue and organ transplantation.

Published Works

• GENETIC CONTROL OF THE IMMUNE RESPONSE
• THE INFLUENCE OF THE GONADS AND ADRENAL GLANDS ON THE IMMUNE RESPONSE TO SKIN GRAFTS
• Strong and Weak Histocompatibility Gene Differences in Mice and Their Role in the Rejection of Homografts of Tumors and Skin
• DEPRESSION BY ANTIBODY OF THE IMMUNE RESPONSE TO HOMOGRAFTS AND ITS ROLE IN IMMUNOLOGICAL ENHANCEMENT
• HISTOCOMPATIBILITY GENES OF MICE
• A translocation in the house mouse and its effect on development
• Ly-6.2: A new lymphocyte specificity of peripheral T-cells
• THE CUMULATIVE EFFECT OF HISTOCOMPATIBILITY ANTIGENS1
• HEMAGGLUTINATION AND CYTOTOXIC STUDIES OF H-2
• X-ray sterility in the male house mouse
Abnormal development in the mouse caused by chromosome unbalance
HISTOCOMPATIBILITY GENES OF MICE VII. H-13, A NEW HISTOCOMPATIBILITY LOCUS IN THE FIFTH LINKAGE GROUP
HISTOCOMPATIBILITY GENES OF MICE. V. FIVE NEW HISTOCOMPATIBILITY LOCI IDENTIFIED BY CONGENIC RESISTANT LINES ON A C57BL/10 BACKGROUND
COMPARATIVE IMMUNOGENICITY AND ENHANCEABILITY OF INDIVIDUAL H-2K AND H-2D SPECIFICITIES OF THE MURINE HISTOCOMPATIBILITY-2 COMPLEX
DUCKY, A NEW SECOND CHROMOSOME MUTATION IN THE MOUSE
Harelip, a new mutation in the house mouse
HEMAGGLUTINATION AND CYTOTOXIC STUDIES OF H-2 II. SOME NEW CYTOTOXIC SPECIFICITIES
INHERITANCE IN THE HOUSE MOUSE, THE LINKAGE RELATIONS OF SHORT-EAR, HAIRLESS, AND NAKED
THE INDUCTION BY X-RAYS OF HEREDITARY CHANGES IN MICE
HISTOCOMPATIBILITY GENES OF MICE
A technique for the artificial insemination of mice
THE IMPORTANCE OF TARGET SIZE IN THE DESTRUCTION OF SKIN GRAFTS WITH NON-H-2 INCOMPATIBILITY
HISTOCOMPATIBILITY GENES OF MICE
Linkage of loop-tail, leaden, splotch and fuzzy in the mouse
Immunogenetics: Retrospect and prospect
HISTOCOMPATIBILITY GENES OF MICE VIII. THE ALLELES OF THE H-1 LOCUS
Induction by Roentgen Rays of Hereditary Changes in Mice
Recent Advances in Histocompatibility Immunogenetics
AN ANALYSIS OF TRANSLOCATIONS IN THE MOUSE
TESTS OF ALTERNATIVE METHODS FOR DEMONSTRATING THE HISTO-COMPATABILITY-1 ISOANTIGEN IN MICE
LINKAGE GROUP XVIII OF THE MOUSE
CONGENIC RESISTANT STRAINS OF MICE
HISTOCOMPATIBILITY GENES OF MICE
THE GENETICS OF TRANSPLANTATION
The Role of Male Parthenogenesis in the Evolution of the Social Hymenoptera
EVIDENCE THAT THE “R” AND “Z” BLOOD GROUP SPECIFICITIES OF MICE ARE ALLELIC AND DISTINCT FROM H-2
The alleles of theH-13 locus
Studies in Histocompatihility
ALLELES AT THE HISTOCOMPATIBILITY-2 LOCUS IN THE MOUSE AS DETERMINED BY TUMOR TRANSPLANTATION
DETECTION OF A NON-H-2 BLOOD GROUP SYSTEM WITH THE AID OF B10.129(5M) MICE
A DESCRIPTION OF MU: A NON-H-2 ALLOANTIGEN IN C3H/Sn MICE
Preliminary data on crossing over between H-2 and Fu, Ki and T in the mouse
Search for a Rational Ethic
Some recollections of Peter Gorer and his work on this fiftieth anniversary of his discovery of H-2
Some Considerations Concerning the Structure of Chromosomes and Genes
IMMUNOGENICITY AND ENHANCEMENT FOR THE PRIVATE SPECIFICITIES H-2.12,16,20, AND 211
Genetic symbols: How do we get good ones?
THE HLA COMPLEX: SEROLOGY AND GENETICS
A technique for the preparation of sections of early mouse embryos
HISTOGENETIC METHODS
SEROLOGICALLY DEMONSTRATED MEMBRANE ALLOANTIGENS OF MICE
ALLOGENETIC CELL INTERACTIONS UNIQUELY DEPENDENT ON H-2
BIOCHEMICAL AND STRUCTURAL PROPERTIES OF THE CELL MEMBRANE LOCATED ALLOANTIGENS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX
HISTOCOMPATIBILITY GENES AND DISEASE
THE ALLOGENEIC RESPONSE
Hybrids and History. The Role of Race and Ethnic Crossing in Individual and National Achievement
INHERITANCE OF RINGED HAIR
HISTOCOMPATIBILITY GENES OF MICE
Introduction
A Revolutionary Age
What’s Gone Wrong?
The Biological Background of Social Behavior: Genetic Factors
The Biological Background of Social Behavior: Evolutionary Factors
What Is Ethics?
The Rules We Live By
Looking to the Future
Thirteen new chromosome-7 congenic lines
Book reviews
Book review
The last of the just
The Last of the Just
DIFFERENCES BETWEEN C57BL STRAINS AT AN ERYTHROCYTE ANTIGEN LOCUS
PREFACE
ISOGRAFTS SUCCEED, ALLOGRAFTS FAIL
THE NUMBER AND DIVERSITY OF HISTOCOMPATIBILITY LOCI
IMMUNOGENETIC METHODS
SEROLOGICALLY AND HISTOGENETICALLY DEMONSTRATED LOCI OF THE H-2 COMPLEX
IMMUNE RESPONSE GENES
THE HLA COMPLEX: PRACTICAL IMPLICATIONS
A Symposium on Mammary Tumors in Mice. Publication of the American Association for the advancement of Science No. 22.Members of the Staff of the National Cancer Institute., National Institute of Health., United States Public Health Service.
Methodology in Mammalian Genetics.Walter J. Burdette
Scientists and Their Responsibility.William R. Shea , Beat Sitter
INHERITANCE IN THE HOUSE MOUSE, THE LINKAGE RELATIONS OF SHORT-EAR, HAIRLESS, AND NAKE
HISTOCOMPATIBILITY GENES OF MICE
H-2: Its Structure and Similarity to HL-A
Biology of the laboratory mouse, by the staff of the Roscoe B. Jackson memorial laboratory, Clarence C. Little, director, George D. Snell, editor [and others] ... with a chapter on Infectious diseases of mice, by J.H. Dingle ...
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Other Resources

• en.wikipedia.org

Schools

Harvard University

Private research university in Cambridge, Massachusetts, United States

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Dartmouth College

University and liberal arts college in Hanover, New Hampshire, United States

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