Inder Verma
#8,691
Most Influential Person Now
American–Indian academic; PNAS editor-in-chief
Why Is Inder Verma Influential?
(Suggest an Edit or Addition)According to Wikipedia, Inder Mohan Verma is an Indian American molecular biologist, the former Cancer Society Professor of Molecular Biology in the Laboratory of Genetics at the Salk Institute for Biological Studies and the University of California, San Diego. He is recognized for seminal discoveries in the fields of cancer, immunology, and gene therapy.
Inder Verma's Published Works
Published Works
- In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector (1996) (4939)
- NF-κB regulation in the immune system (2002) (2530)
- Suppression of TNF-α-Induced Apoptosis by NF-κB (1996) (2298)
- Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation. (1995) (1760)
- Gene therapy - promises, problems and prospects (1997) (1712)
- Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector. (1996) (1600)
- NF-kappaB regulation in the immune system. (2002) (1596)
- Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor (1990) (1208)
- Development of a Self-Inactivating Lentivirus Vector (1998) (1172)
- An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma (2019) (1007)
- Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene (1999) (948)
- Production and purification of lentiviral vectors (2006) (919)
- Expression of cellular oncogenes in human malignancies. (1984) (829)
- Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein (1984) (775)
- The pCL vector system: rapid production of helper-free, high-titer, recombinant retroviruses (1996) (759)
- Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector (1997) (744)
- Suppression of TNF-alpha-induced apoptosis by NF-kappaB. (1996) (732)
- NF-κB, an Active Player in Human Cancers (2014) (724)
- Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells (2009) (698)
- Gene therapy: trials and tribulations (2000) (680)
- Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network (2007) (673)
- Transduction of human CD34+ cells that mediate long-term engraftment of NOD/SCID mice by HIV vectors. (1999) (661)
- Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors (1997) (651)
- Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression. (1995) (631)
- Gene therapy: twenty-first century medicine. (2005) (607)
- Induction of proto-oncogene JUN/AP-1 by serum and TPA (1988) (584)
- A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA (2003) (578)
- The Knockout Mouse Project (2004) (574)
- FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA (1982) (566)
- Transgenesis by lentiviral vectors: Lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos (2002) (543)
- Transcriptional autoregulation of the proto-oncogene fos (1988) (533)
- c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene (1984) (530)
- Retinoic acid is a negative regulator of AP-1-responsive genes. (1991) (528)
- Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. (1997) (523)
- IKK1-deficient mice exhibit abnormal development of skin and skeleton. (1999) (505)
- R~~/NF-KB /IKB familv: intimate tales of association and dissociation (1995) (501)
- Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice (2012) (496)
- Differential expression of cellular oncogenes during pre- and postnatal development of the mouse (1982) (494)
- Transdifferentiation of glioblastoma cells into vascular endothelial cells (2011) (480)
- Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice (2005) (461)
- Viral and cellular fos proteins: A comparative analysis (1984) (460)
- Transcriptional activation by BRCA1 (1996) (454)
- Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini (1983) (446)
- Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. (2009) (439)
- BRCA1 tumor suppression occurs via heterochromatin mediated silencing (2011) (436)
- Cationic liposome-mediated RNA transfection. (1989) (420)
- Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus (1986) (419)
- fos-associated cellular p39 is related to nuclear transcription factor AP-1 (1988) (415)
- Autoregulation of I kappa B alpha activity. (1994) (407)
- Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain (1988) (403)
- Reciprocal Role of ERK and Nf-κb Pathways in Survival and Activation of Osteoclasts (2000) (392)
- Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model (2005) (389)
- Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein. (1983) (386)
- Dedifferentiation and reprogramming: origins of cancer stem cells (2014) (382)
- Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity (2001) (378)
- Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice (2003) (371)
- Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer (2015) (371)
- Expression cloning of human EGF receptor complementary DNA: gene amplification and three related messenger RNA products in A431 cells. (1984) (369)
- Functional antagonism between c-Jun and MyoD proteins: A direct physical association (1992) (368)
- Nuclear proto-oncogenes fos and jun. (1990) (362)
- A Fourth IκB Protein within the NF-κB Signaling Module (2007) (360)
- Induction of proto-oncogene fos transcription through the adenylate cyclase pathway: characterization of a cAMP-responsive element. (1988) (359)
- Severe liver degeneration in mice lacking the IkappaB kinase 2 gene. (1999) (357)
- Inhibition of TNF-induced apoptosis by NF-κB (1998) (356)
- Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. (1984) (352)
- Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation (1985) (349)
- c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I. (1988) (339)
- NF-κB regulation in the immune system (2002) (337)
- The NIH Roadmap (2004) (336)
- Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment. (2010) (335)
- Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines (2012) (327)
- Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene (1985) (324)
- Muscle-specific transcriptional activation by MyoD. (1991) (322)
- Gene therapy: promises and problems. (2001) (313)
- Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivo. (1992) (309)
- p53 stabilization is decreased upon NFκB activation (2002) (306)
- Development of a novel mouse glioma model using lentiviral vectors (2009) (295)
- Gene therapy: Therapeutic gene causing lymphoma (2006) (294)
- Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma (2011) (290)
- A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity (2011) (290)
- Induction of the proto-oncogene fos by nerve growth factor. (1985) (287)
- Gene therapy with viral vectors. (2003) (276)
- Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy. (1998) (274)
- Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration (2009) (274)
- A Packaging Cell Line for Lentivirus Vectors (1999) (271)
- Structure of the FBJ murine osteosarcoma virus genome: molecular cloning of its associated helper virus and the cellular homolog of the v-fos gene from mouse and human cells (1983) (270)
- Functional Gene Correction for Cystic Fibrosis in Lung Epithelial Cells Generated from Patient iPSCs. (2015) (270)
- Long-term in vivo expression of retrovirus-mediated gene transfer in mouse fibroblast implants. (1991) (269)
- Proto-oncogene fos: Complex but versatile regulation (1987) (266)
- Inflammation-associated cancer: NF-κB is the lynchpin (2005) (263)
- Rel/NF-kappa B/I kappa B story. (1995) (262)
- Lentiviral vectors: regulated gene expression. (2000) (249)
- Regulated mRNA stability. (1990) (247)
- Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivo (2001) (243)
- Cationic liposome-mediated RNA transfection. (1993) (239)
- CBP/p300 interact with and function as transcriptional coactivators of BRCA1. (2000) (239)
- Sustained correction of bleeding disorder in hemophilia B mice by gene therapy. (1999) (231)
- CtIP links DNA double-strand break sensing to resection. (2009) (230)
- Glioblastoma Model Using Human Cerebral Organoids (2018) (228)
- Rescue from Photoreceptor Degeneration in therd Mouse by Human Immunodeficiency Virus Vector-Mediated Gene Transfer (1999) (225)
- Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb (1998) (221)
- The fos oncogene. (1987) (217)
- Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells (2014) (214)
- Viral and cellular fos proteins are complexed with a 39,000-dalton cellular protein (1985) (214)
- Activation of Transcription Factor NF-κB Requires ELKS, an IκB Kinase Regulatory Subunit (2004) (213)
- Complete lack of NF-kappaB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation. (2000) (213)
- Pharmacological activation of REV-ERBs is lethal in cancer and oncogene induced senescence (2018) (212)
- Enhancement of BRCA1 E3 Ubiquitin Ligase Activity through Direct Interaction with the BARD1 Protein* (2003) (211)
- A fourth IkappaB protein within the NF-kappaB signaling module. (2007) (210)
- Nucleotide sequence of the genome of a murine sarcoma virus (1981) (208)
- mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element (1990) (206)
- Generation of targeted retroviral vectors by using single-chain variable fragment: an approach to in vivo gene delivery. (1995) (206)
- Targeted delivery of proteins across the blood–brain barrier (2007) (206)
- IκB kinase: Beginning, not the end (1997) (203)
- BRCA1 is a cell cycle-regulated nuclear phosphoprotein. (1997) (200)
- Astrocytes contribute to gamma oscillations and recognition memory (2014) (198)
- Bimp1, a MAGUK Family Member Linking Protein Kinase C Activation to Bcl10-mediated NF-κB Induction* (2001) (195)
- IκBγ, a 70 kd protein identical to the C-terminal half of p110 NF-κB: A new member of the IκB family (1992) (194)
- Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B. (1994) (194)
- Transparency in authors’ contributions and responsibilities to promote integrity in scientific publication (2017) (192)
- Adeno-associated virus effectively mediates conditional gene modification in the brain (2002) (190)
- IKK biology (2012) (190)
- Repopulation of adult and neonatal mice with human hepatocytes: A chimeric animal model (2007) (187)
- Negative and positive regulation by transcription factor cAMP response element-binding protein is modulated by phosphorylation. (1990) (186)
- Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression (2010) (183)
- Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases (2012) (181)
- An alternative approach to somatic cell gene therapy. (1988) (180)
- Sustained expression of therapeutic level of factor IX in hemophilia B dogs by AAV-mediated gene therapy in liver. (2000) (179)
- Gene delivery of human apolipoprotein E alters brain Abeta burden in a mouse model of Alzheimer's disease. (2005) (179)
- Systemic delivery of factor IX messenger RNA for protein replacement therapy (2017) (178)
- A factor IX-deficient mouse model for hemophilia B gene therapy. (1997) (177)
- Enhanced I kappa B alpha degradation is responsible for constitutive NF-kappa B activity in mature murine B-cell lines (1994) (176)
- Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors. (2001) (176)
- Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells (2003) (176)
- Sustained correction of disease in naive and AAV2-pretreated hemophilia B dogs: AAV2/8-mediated, liver-directed gene therapy. (2005) (175)
- EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis. (2012) (174)
- A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT. (1983) (174)
- Immunological defects in mice with a targeted disruption in Bcl-3. (1997) (173)
- Modification of fos proteins: phosphorylation of c-fos, but not v-fos, is stimulated by 12-tetradecanoyl-phorbol-13-acetate and serum (1987) (172)
- Removal of a 67-base-pair sequence in the noncoding region of protooncogene fos converts it to a transforming gene. (1985) (171)
- p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy. (2002) (167)
- In vitro synthesis of DNA complementary to rabbit reticulocyte 10S RNA. (1972) (167)
- c-fos expression is neither sufficient nor obligatory for differentiation of monomyelocytes to macrophages (1986) (166)
- Transcription of c-onc genes c-rasKi and c-fms during mouse development (1983) (165)
- Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha (1996) (164)
- Both the basic region and the ‘leucine zipper’ domain of the cyclic AMP response element binding (CREB) protein are essential for transcriptional activation. (1990) (164)
- Phosphorylation of the C terminus of Fos protein is required for transcriptional transrepression of the c-fos promoter (1990) (163)
- Cross-talk in signal transduction: TPA-inducible factor jun/AP-1 activates cAMP-responsive enhancer elements. (1990) (162)
- Nucleotide sequence and formation of the transforming gene of a mouse sarcoma virus (1981) (161)
- Truncated BRCA2 is cytoplasmic: implications for cancer-linked mutations. (1999) (160)
- Tissue and cell type-specific expression of two human c-onc genes (1983) (159)
- Neprilysin: an enzyme candidate to slow the progression of Alzheimer's disease. (2008) (156)
- Constitutive phosphorylation of I kappa B alpha by casein kinase II. (1995) (156)
- IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy (2003) (155)
- Suppression of angiogenesis by lentiviral delivery of PEX, a noncatalytic fragment of matrix metalloproteinase 2. (2000) (154)
- Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB (1993) (153)
- Expression of a retrovirus encoding human HPRT in mice. (1984) (153)
- LFG: an anti-apoptotic gene that provides protection from Fas-mediated cell death. (1999) (152)
- Little evidence of bone marrow-derived hepatocytes in the replacement of injured liver (2003) (151)
- CRE recombinase-inducible RNA interference mediated by lentiviral vectors. (2004) (148)
- Inflammation-associated cancer: NF-kappaB is the lynchpin. (2005) (147)
- Phosphorylation of SNAP-23 by IκB Kinase 2 Regulates Mast Cell Degranulation (2008) (146)
- Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma. (2021) (146)
- The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain (1990) (146)
- Distinct roles of IκB proteins in regulating constitutive NF-κB activity (2005) (145)
- Fos-Jun interaction: mutational analysis of the leucine zipper domain of both proteins. (1989) (143)
- Expression of c‐onc genes: c‐fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion. (1983) (142)
- Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow. (2002) (141)
- An alternative spliced form of FosB is a negative regulator of transcriptional activation and transformation by Fos proteins. (1991) (138)
- Phosphorylation of p53 by IκB kinase 2 promotes its degradation by β-TrCP (2009) (138)
- Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme (2013) (137)
- Identification of a transcriptional enhancer element upstream from the proto-oncogene fos. (1985) (137)
- Qualitative changes in the subunit composition of kappa B-binding complexes during murine B-cell differentiation. (1994) (135)
- Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor. (2000) (134)
- Nuclear factor (NF)-κB proteins: therapeutic targets* (2004) (133)
- Proto-oncogene expression in regenerating liver is simulated in cultures of primary adult rat hepatocytes. (1986) (133)
- The autoregulated instability of Polo-like kinase 4 limits centrosome duplication to once per cell cycle. (2012) (126)
- Efficient insertion of genes into the mouse germ line via retroviral vectors. (1985) (124)
- BRCA1 Is Phosphorylated at Serine 1497 In Vivo at a Cyclin-Dependent Kinase 2 Phosphorylation Site (1999) (124)
- The rel-associated pp40 protein prevents DNA binding of Rel and NF-kappa B: relationship with I kappa B beta and regulation by phosphorylation. (1991) (123)
- Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. (2006) (122)
- Signal-dependent and -independent Degradation of Free and NF-κB-bound IκBα* (2000) (121)
- Detection of a transforming gene product in cells transformed by Moloney murine sarcoma virus (1982) (121)
- Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging. (2001) (121)
- ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun (1989) (120)
- Enhanced NF-κB activation and cellular function in macrophages lacking IκB kinase 1 (IKK1) (2005) (120)
- Detection of fos protein during osteogenesis by monoclonal antibodies (1988) (118)
- Regulation of β-Catenin Function by the IκB Kinases* (2001) (117)
- Studies on reverse transcriptase of RNA tumor viruses III. Properties of purified Moloney murine leukemia virus DNA polymerase and associated RNase H (1975) (117)
- Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer. (2011) (115)
- Reduced cell proliferation by IKK2 depletion in a mouse lung cancer model (2012) (115)
- Long terminal repeat of murine retroviral DNAs: sequence analysis, host-proviral junctions, and preintegration site (1982) (115)
- Suppression of PPAR-γ attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes (2007) (113)
- Covalently linked RNA-DNA molecule as initial product of RNA tumour virus DNA polymerase. (1971) (112)
- Restoration of spermatogenesis by lentiviral gene transfer: Offspring from infertile mice (2002) (112)
- Analysis of the env gene of a molecularly cloned and biologically active Moloney mink cell focus-forming proviral DNA (1982) (110)
- Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis. (1998) (110)
- The reverse transcriptase. (1977) (109)
- Efficient production of human FVIII in hemophilic mice using lentiviral vectors. (2003) (109)
- Nucleotide sequence of Moloney leukemia virus: 3' end reveals details of replications, analogy to bacterial transposons, and an unexpected gene. (1980) (108)
- Direct association of pp40/I kappa B beta with rel/NF-kappa B transcription factors: role of ankyrin repeats in the inhibition of DNA binding activity. (1992) (108)
- Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line. (1993) (107)
- Characterization of NF-κΒ/IκΒ Proteins in Zebra Fish and Their Involvement in Notochord Development (2004) (105)
- c-rel activates but v-rel suppresses transcription from kappa B sites. (1991) (103)
- Applications of lentiviral vectors for shRNA delivery and transgenesis. (2008) (102)
- Structure of Moloney murine leukemia viral DNA: nucleotide sequence of the 5' long terminal repeat and adjacent cellular sequences. (1980) (102)
- Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes. (2002) (101)
- Bcl-xL protects adult septal cholinergic neurons from axotomized cell death. (1998) (97)
- Applications of gene therapy to the CNS. (1996) (96)
- NF-κB and the regulation of hematopoiesis (2006) (95)
- The proto-oncogene BCL-3 encodes an IκB protein (1992) (95)
- Lentiviral vectors, two decades later (2016) (94)
- Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs. (1990) (93)
- A Structural Basis for IκB Kinase 2 Activation Via Oligomerization-Dependent Trans Auto-Phosphorylation (2013) (93)
- Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock (2007) (93)
- Proto-oncogene fos: a multifaceted gene (1986) (93)
- Transformation by Fos proteins requires a C-terminal transactivation domain (1993) (92)
- Design and cloning of lentiviral vectors expressing small interfering RNAs (2006) (92)
- Inhibition of TNF-induced apoptosis by NF-kappa B. (1998) (92)
- Genic regions of a large salamander genome contain long introns and novel genes (2009) (92)
- Targeting NF-κB in glioblastoma: A therapeutic approach (2016) (91)
- Generation of transgenic mice using lentiviral vectors: a novel preclinical assessment of lentiviral vectors for gene therapy. (2003) (91)
- FBR murine osteosarcoma virus. II. Nucleotide sequence of the provirus reveals that the genome contains sequences acquired from two cellular genes. (1984) (91)
- Modulation of c-"os gene transcription by negative and positive cellular factors (1987) (90)
- NF-κB-Mediated Inhibition of Apoptosis Is Required for Encephalomyocarditis Virus Virulence: a Mechanism of Resistance in p50 Knockout Mice (1998) (90)
- Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required (1996) (89)
- Nuclear factor (NF)-kappaB proteins: therapeutic targets. (2004) (88)
- Neprilysin regulates amyloid Beta peptide levels. (2004) (87)
- M-MuLV-induced leukemogenesis: Integration and structure of recombinant proviruses in tumors (1981) (87)
- Long-term neprilysin gene transfer is associated with reduced levels of intracellular Abeta and behavioral improvement in APP transgenic mice (2008) (86)
- Tumor suppressor protein (p)53, is a regulator of NF-κB repression by the glucocorticoid receptor (2011) (86)
- FBR murine osteosarcoma virus. I. Molecular analysis and characterization of a 75,000-Da gag-fos fusion product. (1984) (85)
- Differential transcription of exon 1 of the human c-fms gene in placental trophoblasts and monocytes (1989) (85)
- Distinct roles of IkappaB proteins in regulating constitutive NF-kappaB activity. (2005) (85)
- Neprilysin regulates amyloid β peptide levels (2007) (85)
- DNA polymerase activity from two temperature-sensitive mutants of Rous sarcoma virus is thermolabile (1974) (84)
- Human purine nucleoside phosphorylase and adenosine deaminase: gene transfer into cultured cells and murine hematopoietic stem cells by using recombinant amphotropic retroviruses (1987) (84)
- Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral vectors. (2002) (84)
- Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer. (2018) (83)
- Brief Report: Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines (2011) (83)
- Infectious and selectable retrovirus containing an inducible rat growth hormone minigene. (1984) (81)
- BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription (2003) (80)
- A heteroduplex study of the sequence relationships between the RNAs of M-MSV and M-MLV (1977) (80)
- Zebrafish IκB Kinase 1 Negatively Regulates NF-κB Activity (2005) (78)
- Purified I kappa B-beta is inactivated upon dephosphorylation. (1992) (78)
- Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse. (2005) (78)
- Opportunities for the use of lentiviral vectors in human gene therapy. (2002) (76)
- Growth hormone-releasing factor induces c-fos expression in cultured primary pituitary cells. (1987) (76)
- Heteroduplex analysis of the sequence relations between the RNAs of mink cell focus-inducing and murine leukemia viruses (1978) (76)
- Two adjacent promoter elements mediate nerve growth factor activation of the c-fos gene and bind distinct nuclear complexes. (1988) (75)
- Introduction of rat growth hormone gene into mouse fibroblasts via a retroviral DNA vector: expression and regulation. (1982) (75)
- Editorial Expression of Concern: Experimental evidence of massivescale emotional contagion through social networks (2014) (74)
- Signal transduction: the nuclear target. (1992) (74)
- Sustained suppression of Bcr-Abl-driven lymphoid leukemia by microRNA mimics (2007) (72)
- Regulation of beta-catenin function by the IkappaB kinases. (2001) (72)
- Heteroduplex Analysis of the Sequence Relationships Between the Genomes of Kirsten and Harvey Sarcoma Viruses, Their Respective Parental Murine Leukemia Viruses, and the Rat Endogenous 30S RNA (1979) (72)
- Proposed NF-κB/IκB family nomenclature (1993) (72)
- Role of BRCA1 in brain development (2014) (70)
- Expression of cellular oncogenes. (1984) (67)
- A role for IκB kinase 2 in bipolar spindle assembly (2007) (66)
- Studies on the reverse transcriptase of RNA tumor viruses. Structural relatedness of two subunits of avian RNA tumor viruses. (1974) (66)
- Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons. (2005) (65)
- Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes. (2006) (65)
- Two base changes restore infectivity to a noninfectious molecular clone of Moloney murine leukemia virus (pMLV-1) (1984) (64)
- Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs. (2015) (64)
- Light-sheet Bayesian microscopy enables deep-cell super-resolution imaging of heterochromatin in live human embryonic stem cells (2013) (64)
- Proposed NF-kappa B/I kappa B family nomenclature. (1993) (63)
- NF-kappaB and the regulation of hematopoiesis. (2006) (63)
- The Common Thread: A Story of Science, Politics, Ethics and the Human Genome (2002) (63)
- Mitochondrial ribosomal RNA from Aspergillus nidulans: characterization of a novel molecular species. (1970) (62)
- Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis. (2013) (62)
- Peripheral Delivery of a CNS Targeted, Metalo-Protease Reduces Aβ Toxicity in a Mouse Model of Alzheimer's Disease (2011) (62)
- Gene regulation by tyrosine kinases: src protein activates various promoters, including c-fos (1989) (62)
- Transcriptional induction of the murine c-rel gene with serum and phorbol-12-myristate-13-acetate in fibroblasts (1989) (62)
- Impact, not impact factor (2015) (61)
- Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1). (2005) (61)
- Removal of an mRNA destabilizing element correlates with the increased oncogenicity of proto-oncogene fos. (1989) (61)
- Circulating human or canine factor IX from retrovirally transduced primary myoblasts and established myoblast cell lines grafted into murine skeletal muscle (1992) (61)
- Molecular cloning of unintegrated and a portion of integrated moloney murine leukemia viral DNA in bacteriophage lambda (1980) (59)
- A tumultuous year for gene therapy. (2000) (58)
- Trans-dominant negative mutants of Fos and Jun. (1990) (56)
- Signal-dependent and -independent degradation of free and NF-kappa B-bound IkappaBalpha. (2000) (56)
- Elements in the long terminal repeat of murine retroviruses enhance stable transformation by thymidine kinase gene. (1983) (54)
- Direct gene transfer to the liver with herpes simplex virus type 1 vectors: transient production of physiologically relevant levels of circulating factor IX. (1992) (54)
- Making the promise a reality. (2002) (53)
- Purification of the RNA-directed DNA polymerase from avian myeloblastosis virus and its assay with polynucleotide templates. (1974) (53)
- Size analysis and relationship of murine leukemia virus-specific mRNA's: evidence for transposition of sequences during synthesis and processing of subgenomic mRNA (1978) (53)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells (2016) (51)
- Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in the c-Fos protein augments its transforming potential (1992) (49)
- Neprilysin protects neurons against Aβ peptide toxicity (2007) (48)
- Analysis of transforming gene products from moloney murine sarcoma virus (1981) (48)
- Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IκBα (1997) (48)
- Efficient transgenic rat production by a lentiviral vector (2006) (47)
- Studies on reverse transcriptase of RNA tumor viruses. I. Localization of thermolabile DNA polymerase and RNase H activities on one polypeptide (1975) (47)
- Human c-fos oncogene mapped within chromosomal region 14q21----q31. (1984) (47)
- Long-term lowering of plasma cholesterol levels in LDL-receptor-deficient WHHL rabbits by gene therapy. (2004) (46)
- NUCLEOTIDE SEQUENCES OF HUMAN GLOBIN MESSENGER RNA * (1974) (46)
- Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes. (2007) (46)
- IkappaB kinase: beginning, not the end. (1997) (46)
- Adenovirus‐mediated overexpression of follistatin enlarges intact liver of adult rats (2003) (45)
- Characterization of NF-kappa B/I kappa B proteins in zebra fish and their involvement in notochord development. (2004) (45)
- A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin (2014) (45)
- Polo-like kinase 4 controls centriole duplication but does not directly regulate cytokinesis (2012) (44)
- Covalent Linkage Between Ribonucleic Acid Primer and Deoxyribonucleic Acid Product of the Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase (1972) (44)
- Positive control mutations in the MyoD basic region fail to show cooperative DNA binding and transcriptional activation in vitro. (1994) (43)
- Regulation of proto-oncogene fos: a paradigm for early response genes. (1988) (43)
- Domain swapping reveals the modular nature of Fos, Jun, and CREB proteins (1990) (42)
- Thermolabile reverse transcriptase of a mammalian leukemia virus mutant temperature sensitive in its replication and sarcoma virus helper functions (1975) (41)
- Constitutive Phosphorylation of IkBa by Casein Kinase II Occurs Preferentially at Serine 293: Requirement for Degradation of Free IkBa (1996) (41)
- Gene Therapy That Works (2013) (40)
- Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells. (2010) (39)
- Cleavage of the leptin receptor by matrix metalloproteinase–2 promotes leptin resistance and obesity in mice (2018) (39)
- Structural Basis for the Activation of IKK1/α (2016) (39)
- CREB represses transcription of fos promoter: role of phosphorylation. (1991) (39)
- Development of ecdysone-regulated lentiviral vectors. (2005) (39)
- Retrovirus-mediated gene transfer into embryonal carcinoma and hemopoietic stem cells: expression from a hybrid long terminal repeat. (1989) (38)
- Transformation by FosB requires a trans-activation domain missing in FosB2 that can be substituted by heterologous activation domains. (1992) (38)
- The proto-oncogene bcl-3 encodes an I kappa B protein. (1992) (37)
- A role for IkappaB kinase 2 in bipolar spindle assembly. (2007) (36)
- Identification of a RNA polymerase II initiation site in the long terminal repeat of Moloney murine leukemia viral DNA. (1981) (36)
- A Fourth IkB Protein within the NF-kB Signaling Module (2007) (35)
- Genome organization of RNA tumor viruses. I. In vitro synthesis of full-genome-length single-stranded and double-stranded viral DNA transcripts (1978) (35)
- Reverse transcriptase of RNA tumor viruses. V. In vitro proteolysis of reverse transcriptase from avian myeloblastosis virus and isolation of a polypeptide manifesting only RNase H activity (1978) (35)
- Proto-oncogene FosB: the amino terminus encodes a regulatory function required for transformation (1993) (35)
- Identification of a nuclear targeting sequence in the Fos protein. (1991) (35)
- Kappa B enhancer-binding complexes that do not contain NF-kappa B are developmentally regulated in mammalian brain. (1994) (35)
- I kappa B gamma, a 70 kd protein identical to the C-terminal half of p110 NF-kappa B: a new member of the I kappa B family. (1992) (34)
- The bZIP domains of Fos and Jun mediate a physical association with the TATA box-binding protein. (1993) (33)
- A Neuroprotective Brain-penetrating Endopeptidase Fusion Protein Ameliorates Alzheimer Disease Pathology and Restores Neurogenesis* (2014) (33)
- Hamster Leukemia Virus: Lack of Endogenous DNA Synthesis and Unique Structure of Its DNA Polymerase (1974) (33)
- Moloney murine leukemia virus-induced tumors: recombinant proviruses in active chromatin regions. (1982) (32)
- Zebrafish IkappaB kinase 1 negatively regulates NF-kappaB activity. (2005) (31)
- A role for bone marrow-derived cells in the vasculature of noninjured CNS. (2005) (30)
- Gene therapy: reality or myth for the global bleeding disorders community? (2002) (30)
- Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma (2015) (30)
- Identification and molecular cloning of Moloney mouse sarcoma virus-specific sequences from uninfected mouse cells (1980) (29)
- Antiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cells (2011) (29)
- 3 Lentiviral Vectors (1999) (29)
- Retroviral Vector Targeting to Human Immunodeficiency Virus Type 1-Infected Cells by Receptor Pseudotyping (2000) (29)
- EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis. (2018) (29)
- Molecular cloning of unintegrated Moloney mouse sarcoma virus DNA in bacteriophage lambda. (1980) (28)
- c-rel activates but v-rel suppresses transcription from KB sites (28)
- Deletion of the gag region from FBR murine osteosarcoma virus does not affect its enhanced transforming activity (1985) (28)
- Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation (2016) (27)
- Rapid generation of knockdown transgenic mice by silencing lentiviral vectors (2006) (27)
- Size determination of mitochondrial ribosomal RNA from Aspergillus nidulans by electron microscopy. (1970) (26)
- Gene Therapy: Hopes, Hypes, and Hurdles (1994) (25)
- Targeting CREB Pathway Suppresses Small Cell Lung Cancer (2018) (25)
- Autologous and Heterologous Cell Therapy for Hemophilia B toward Functional Restoration of Factor IX (2018) (25)
- Neprilysin protects neurons against Abeta peptide toxicity. (2007) (25)
- Synthesis of DNA complementary to cellular slime mold messenger RNA by reverse transcriptase. (1974) (24)
- Homology among oncogenes. (1986) (24)
- Towards gene therapy for hemophilia B. (1987) (24)
- Genome organization of retroviruses. VI. Heteroduplex analysis of ecotropic and xenotropic sequences of moloney mink cell focus-inducing viral RNA obtained from either a cloned isolate or a thymoma cell line (1979) (24)
- Characterization of "early" temperature-sensitive mutants of avian sarcoma viruses: biological properties, thermolability of reverse transcriptase in vitro, and synthesis of viral DNA in infected cells. (1976) (23)
- Physico-chemical properties of mitochondrial ribosomal RNA from fungi. (1971) (22)
- Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses. (1990) (22)
- fos and jun interaction: The role of the leucine zipper (1989) (22)
- Signal-Induced Degradation of IkBa: Association with NF-kB and the PEST Sequence in IkBa Are Not Required (1996) (22)
- Genome organization of RNA tumor viruses II. Physical maps of in vitro-synthesized Moloney murine leukemia virus double-stranded DNA by restriction endonucleases (1978) (22)
- Identification of therapeutic targets for glioblastoma by network analysis (2016) (21)
- Genome organization of retroviruses IX. Analysis of the genomes of Friend spleen focus-forming (F-SFFV) and helper murine leukemia viruses by heteroduplex-formation. (1980) (21)
- Dovitinib enhances temozolomide efficacy in glioblastoma cells (2017) (20)
- Corrigendum: Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model (2015) (20)
- Oncogenic intelligence: From c-fos to v-fos (1984) (20)
- Role of the subunits of the avian RNA tumor virus reverse transcriptase. (1975) (20)
- Choroidal neovascularization in transgenic mice expressing prokineticin 1: an animal model for age-related macular degeneration. (2006) (20)
- Retroviral vectors for persistent expression in vivo. (1992) (19)
- Erratum: Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma (Proc Natl Acad Sci USA (2011) 108 (17450-17455) DOI: 10.1073/pnas.1114518108) (2014) (19)
- Overexpression of the FosB2 gene in thymocytes causes aberrant development of T cells and thymic epithelial cells (1997) (19)
- Synthesis of DNA complementary to 14S calf lens crystallin messenger RNA by reverse transcriptase. (1973) (19)
- Identification and molecular cloning of Moloney mouse sarcoma virus-specific sequences from uninfected mouse cells. (1980) (18)
- Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection (2011) (17)
- SNW1, a Novel Transcriptional Regulator of the NF-κB Pathway (2018) (16)
- Proto-oncogene fos is expressed during development, differentiation, and growth. (1985) (16)
- Expression of FBJ-MSV oncogene (fos) product in bacteria. (1983) (16)
- Retroviral vectors for persistent expression in vivo (1992) (15)
- Inflammatory tales of liver cancer. (2007) (15)
- Developmental expression of the Xenopus laevis fos protooncogene. (1990) (15)
- Direct involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalpha. (1997) (14)
- Genome Organization of Retroviruses V. In Vitro-Synthesized Moloney Murine Leukemia Viral DNA Has Long Terminal Redundancy (1980) (14)
- BRCA1/BARD1-dependent ubiquitination of NF2 regulates Hippo-YAP1 signaling (2019) (14)
- Long-term expression of a retrovirally introduced β-galactosidase gene in rodent cells implanted in vivo using biodegradable polymer meshes (1992) (14)
- Effect of adenovirus-mediated overexpression of follistatin and extracellular domain of activin receptor type II on gonadotropin secretion in vitro and in vivo. (2002) (13)
- Piecing together more efficient gene expression (1999) (13)
- fos-jun conspiracy: implications for the cell. (1990) (13)
- Diverse molecular mechanisms of inhibition of NF-kappa B/DNA binding complexes by I kappa B proteins. (1993) (13)
- Revertants of v-fos-transformed rat fibroblasts: suppression of transformation is dominant (1990) (12)
- Transformation by Jun: requirement for leucine zipper, basic region and transactivation domain and enhancement by Fos. (1992) (12)
- Essential role of tuberous sclerosis genes TSC 1 and TSC 2 in NFk B activation and cell survival (12)
- A comparison of nucleotide sequences from mitochondrial and cytoplasmic ribosomal RNA of Aspergillus nidulans. (1971) (11)
- c-fos promoter transactivation by the tax , protein of human T-cell leukemia virus type I ( transcription / regulatory elements / oncogenesis ) (11)
- Stem cells at the dawn of the 21st century (2003) (11)
- Biopiracy: distrust widens the rich-poor divide. (2002) (11)
- Matrix metalloproteinase/integrin interactions as target for anti-angiogenic treatment strategies. (2002) (11)
- Silence of the genes. (2004) (11)
- Mammalian retrovirus-associated RNase H is virus coded (1978) (11)
- A voluntary moratorium? (2003) (10)
- Temperature‐sensitive dna polymerase from rous sarcoma virus mutants (1974) (10)
- Characterization and purification of human fos protein generated in insect cells with a baculoviral expression vector (1990) (10)
- Expression of c-onc genes c-fos and c-fms in developing mouse tissues (1983) (10)
- Preprint servers facilitate scientific discourse (2017) (10)
- Genome organization of retroviruses. VII. Infection by double-stranded DNA synthesized in vitro from Moloney murine leukemia virus generates a virus indistinguishable from the original virus used in reverse transcription. (1980) (9)
- [35] – Cationic Liposome-Mediated RNA Transfection (1995) (9)
- Optical absorbance properties of mitochondrial ribosomal RNA. (1971) (9)
- Lentiviral vectors for retrograde delivery of recombinases and transactivators. (2015) (9)
- Association of nuclear oncoproteins fos and jun. (1989) (9)
- Development of Lentiviral Vectors Expressing siRNA (2007) (9)
- Modeling Gliomas Using Two Recombinases. (2019) (9)
- Structural Basis for the Activation of IKK1/ alpha. (2016) (9)
- Nucleotide sequences of human globin messenger RNA. (1980) (8)
- Hypothesis-driven science. (2002) (8)
- The Rel-associated pp40 protein prevents DNA binding of Rel and NF-KB: relationship .with IKBI3 and regulation by phosphorylatlon (2007) (8)
- Gene therapy: the need for basic science. (2000) (8)
- Tumor Suppressor p53 Functions as a Negative Regulator in IgE-Mediated Mast Cell Activation (2011) (8)
- Genome organization of retmvinsg. III. Restriction endonuclease cleavage maps of mouse sarcoma virus doub-tranded DNA synthesized in vitro (1979) (8)
- SARS: Fear of global pandemic (2003) (7)
- Recombinant Retroviruses in Transgenic Mice a (1986) (7)
- Genome and gene therapy. (2000) (7)
- [43] Ultraviolet cross-linking of DNA binding proteins (1995) (7)
- Adverse event reporting: essential for science and public trust. (2001) (7)
- Circular dichroism of mitochondrial ribosomal RNA from Trichoderma viride (1971) (6)
- Genome organization of retroviruses. VIII. Nonproducer cell lines of mouse fibroblasts transformed by Moloney murine sarcoma virus DNA synthesized in vitro. (1980) (6)
- “Green light” for gene transfer (1996) (6)
- Gene therapy Hopes, hypes, and hurdles (1996) (6)
- IkappaBalpha . serine 293 : requirement for degradation of free by casein kinase II occurs preferentially at Constitutive phosphorylation of IkappaBalpha (1996) (6)
- Success and setback: another adverse event. (2002) (6)
- Doping, gene transfer and sport. (2004) (5)
- Erratum: EGFR-Induced and PKCε Monoubiquitylation-Dependent NF-κB Activation Upregulates PKM2 Expression and Promotes Tumorigenesis (Molecular Cell (2012) 48(5) (771–784)(S1097276512008283)(10.1016/j.molcel.2012.09.028)) (2012) (5)
- Proto‐oncogene fos: Factors Affecting Expression and Covalent Modification of the Gene Product (1987) (5)
- Gene transfer and gene therapy (1988) (5)
- Gene therapy: beyond 2000. (2000) (5)
- Genetic manipulation of the optical refractive index in living cells (2020) (5)
- Textbook of Gene Therapy (1999) (5)
- Bioscience in India: Times Are Changing (2005) (5)
- Towards Gene Therapy for Adenosine Deaminase Deficiency (1989) (4)
- Looking Back, Looking Ahead (2002) (4)
- Proto-oncogene fos: an inducible gene. (1986) (4)
- Gene therapy: Is IL2RG oncogenic in T-cell development?: X-SCID transgene leukaemogenicity (reply) (2006) (4)
- Knockdown transgenic mice generated by silencing lentiviral vectors: zona pellucida removal and subzonal injection methods. (2007) (4)
- Gene therapy: public education. (2000) (4)
- Expression of the c-fos gene during differentiation. (1987) (4)
- Molecular Therapy's First Year (2001) (4)
- Heteroduplex analysis of the RNA of clone 3 Moloney murine sarcoma virus (1979) (4)
- Gene therapy for thioguanine-resistant human leukemia. (1987) (4)
- Macroporous Dual-compartment Hydrogels for Minimally Invasive Transplantation of Primary Human Hepatocytes (2018) (4)
- Design and Cloning of an shRNA into a Lentiviral Silencing Vector: Version A. (2008) (3)
- Renato Dulbecco (1914–2012) (2012) (3)
- Avian Myeloblastosis Virus DNA Polymerase (1973) (3)
- Efficient and sustained gene transfer in terminally differentiated cells with a lentiviral vector (1997) (3)
- Memory: A model with good CREdentials (1994) (3)
- Organization and Structure of Retrovirus Genomes (1983) (3)
- Agbiotech: success depends on trust. (2004) (3)
- AIDS: Modern concepts and therapeutic challenges Edited by S. Broder. New York: Marcel Dekker, Inc. (1987). 369 pp. $69.75 (1987) (2)
- Targeting oncofetal high mobility group A2 (HMGA2) to increase sensitivity to temozolomide (TMZ) in glioblastoma (GB) cells (2014) (2)
- Erratum: Mesenchymal high-grade glioma is maintained by the ID-RAP1 axis (The Journal of Clinical Investigation (2013) 123:1 (405-417) (DOI: 10.1172/JCI63811) (2014) (2)
- Design and Cloning of an shRNA into a Lentiviral Silencing Vector: Version B. (2008) (2)
- Censorship of scientific publications: a bad idea. (2002) (2)
- PNAS Plus: Refining a successful experiment (2012) (2)
- Mechanisms Defining the Neuronal State Space (2018) (2)
- Determination of sequences in RNA by G.G. Brownlee.: Laboratory techniques in biochemistry and molecular biology. General Editors T. S. Work and E. Work (North-Holland/ American Elsevier Publishing Companies, Amsterdam, London, New York) 1972. (1975) (2)
- Germline gene therapy: yes or no? (2001) (2)
- Time varying causal network reconstruction of a mouse cell cycle (2019) (2)
- Editorial Expression of Concern: Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules (2014) (1)
- Open Access to Scientific Publications (2004) (1)
- Stem cell research: win, win, win by keeping politics out. (2001) (1)
- fos-jun Conspiracy: implications for the cell. (1989) (1)
- Are the benefits of stem cells being oversold? (2001) (1)
- 2002 Nobel Prize for physiology and medicine. (2002) (1)
- Cationic liposome-mediated RNA transfection [ cationic lipid vesicies / N-[ 1-( 2 , 3-dioleyloxy ) propyl ]-NNN-timethylammonium chloride ( DOTMA ) / translationj (1)
- Antiapoptotic Role for Lifeguard in T Cell Mediated Immune Response (2015) (1)
- Then and now (2005) (1)
- Imaging heterochromatin in human embryonic stem cells with light-sheet Bayesian microscopy (2013) (1)
- Potential of adenovirus as a vector for sustained gene expression (1999) (1)
- Celebrating our 20th digital anniversary (2016) (1)
- Human gene therapy. (1991) (1)
- 1081. Sustained Correction of Disease in Na|[iuml]|ve and AAV2-Pretreated Hemophilia B Dogs Using Pseudotyped AAV Vectors (2005) (1)
- From reverse transcriptase to gene therapy: a marvelous journey. (1999) (1)
- Viral and Cellular Fos Gene (1985) (1)
- PNAS introduces new magazine section (2013) (1)
- Illiteracy, ignorance, intolerance=terrorism. (2003) (1)
- Ultraviolet cross-linking of DNA binding proteins. (1995) (1)
- Gene therapy. (1990) (1)
- Inhibitors of NF-κB Activity (2006) (1)
- Avian myeloblastosis virus DNA polymerase: initiation of DNA synthesis and an associated ribonuclease. (1973) (1)
- 700. Targeted delivery of a recombinant protein to neurons and astrocytes by transport and uptake via the low density lipoprotein (LDL) receptor for treatment of neurodegenerative disorders (2004) (1)
- Prokineticin 1 induces choroidal angiogenesis but not retinal angiogenesis; a possible model for the pathogenesis of age–related macular degeneration (2004) (1)
- Gene Therapy: Medicine of the 21stCentury (2003) (1)
- The Long Path to a Career in Science (2004) (1)
- Genome organization of retroviruses. III. Restriction endonuclease cleavage maps of mouse sarcoma virus double-stranded DNA synthesized in vitro. (1979) (1)
- Gene therapy and jurisprudence. (2001) (1)
- Visa crisis hurts U.S. science. (2004) (1)
- Proto-oncogene fos: an inducible multifaceted gene. (1986) (1)
- 2003: we have to do better (2003) (1)
- Good-bye Dolly. (2003) (1)
- Interview with Inder Verma, PhD. (2016) (1)
- An Approach to in vivo Gene Delivery Generation of Targeted Retroviral Vectors by Using Single-Chain Variable Fragment: (2006) (1)
- Pharma + profits = continued aids epidemic. (2001) (1)
- Reverse transcriptase is coded for by the viral RNA. (1975) (1)
- Imaging heterochromatin in human embryonic stem cells with light-sheet Bayesian microscopy (2013) (1)
- Diverse molecular mechanisms of inhibition of NF- k B/DNA binding complexes by I k B proteins (2016) (1)
- Ombudsman or hotline for Gene therapy clinical trials? (2001) (1)
- 1057. Successful Gene Therapy for Retinal Degenerations by Lentiviral Gene Transfer (2004) (0)
- From one experiment to the next. (2005) (0)
- Efficiency of ubiquitous chromatin opening elements in driving the expression of human CD18 within self-inactivating lentiviral vectors for gene therapy applications (2017) (0)
- Recombinant DNA Advisory Committee. Department of Health and Human Services. National Institutes of Health. Minutes of meeting. December 15-16, 1997. (1998) (0)
- New Rules of Publication: Changing Mores (2001) (0)
- Heteroduplex Analysis oftheRNA ofClone3Moloney MurineSarcoma Virus (1979) (0)
- 994. Gene Knockdown in Mice by Using Lentiviral Vectors Expressing Small Interfering RNA (2004) (0)
- Oncogenes as transcription factors:implications for signal transduction. (1992) (0)
- Abstract LB-191: Glioblastomas can originate from neurons in the CNS (2012) (0)
- Short Abstracts – Session I (2007) (0)
- An Unusual Case of Colo-Vesical Fistula (2020) (0)
- Thanks, Adieu and Farewell (2004) (0)
- Abstract A19: Role of NF-κB and gene targets of NF-κB in glioma cell plasticity (2015) (0)
- Bioterrorism: Fear and Reality (2001) (0)
- NF-kBActivation Upregulates PKM2 Expression and Promotes Tumorigenesis (2018) (0)
- Politics and AIDS: a bad mix. (2002) (0)
- Happy 100th Birthday, PNAS (2014) (0)
- Abstract LB-330: A novel role of tumor suppressor BRCA1 in regulating integrity of heterochromatin structure. (2008) (0)
- Gene transfer and gene therapy : proceedings of an E.I. du Pont de Nemours-UCLA Symposium, held at Tamarron, Colorado, February 6-12, 1988 (1989) (0)
- Generation of disease-free hematopoietic progenitors from Fanconi anemia-specific induced pluripotent stem cells (2009) (0)
- Constitutive phosphorylation of IcBa by casein kinase II (2016) (0)
- Skin Fibroblast Derived Inducible Pluripotent Stem Cells To Develop Disease In A Dish Model Of Alport's Disease (2014) (0)
- 3 Development of Lentiviral Vectors (2007) (0)
- Developmental Expression of the Xenopus Iaevis fos (2005) (0)
- The small RNA complement of salamander limb regeneration (2012) (0)
- A Genetic Screen for Genes Involved in BRCA 1 Tumor Suppressor Function (2007) (0)
- Proto-oncogene fos expression and post-translational modification. (1988) (0)
- Impact Factors! (2003) (0)
- QnAs with Inder M. Verma. Interview by Prashant Nair. (2011) (0)
- General Discussion .2. Regulation of the Eukaryotic Cell-Cycle (1990) (0)
- 63. Long-Term Constitutive Expression of the Therapeutic Gene, IL2RG, Causes T-Cell Lymphomas in a Gene Therapy Model for XSCID (2006) (0)
- Enhanced IKBot Degradation Is Responsible for Constitutive NF-KB Activity in Mature Murine B-Cell Lines (0)
- 525. Therapy for Alzheimer's disease by neprilysin gene transfer (2004) (0)
- Disease In A Dish Model Of Cystic Fibrosis From Inducible Pluripotent Stem Cells Derived From Skin Fibroblasts (2014) (0)
- centrosome duplication to once per cell cycle The autoregulated instability of Polo-like kinase 4 limits Material Supplemental (2013) (0)
- 413. Targeting the Low-Density Lipoprotein Receptor on the Blood-Brain Barrier for Transport of β-Glucoronidase Can Treat the Neurological Degeneration of MPSVII (2006) (0)
- Lentiviral Vectors (1999) (0)
- Erratum (2014) (0)
- Do not ban therapeutic cloning. (2002) (0)
- Immunotherapeutics in Cancer Acid Serve as Novel Serum Biomarkers and Human Xeno-Autoantibodies against a Non-Human Sialic (2011) (0)
- Stem cell politics get dirty. (2004) (0)
- Properties and Origin of the Subunits of Reverse Transcriptase Isolated from Avian RNA Tumor Viruses (1975) (0)
- General Discussion .1. the Role of Protooncogenes in Amphibian Development (1990) (0)
- p53 Silencing by Lentiviral Vector Mediated RNA Interference in Murine Hematopoietic Cells and the Development of a Myelogenous Proliferative Disease. (2004) (0)
- A gene therapy institute for NIH? (2002) (0)
- vectors Gene therapy of Fanconi anemia: preclinical efficacy using lentiviral (2013) (0)
- Abstract 975: Glioma cell of origin: Reprogramming and cancer stem cells (2011) (0)
- Abstract 1914: Functional characterization of oncogenic-induced dedifferentiation in neurons and astrocytes using DP-seq (2014) (0)
- Francis Crick: A Personal Memory (2004) (0)
- Novel mouse glioma model: cell-type and region specific activation of oncogenes using lentiviral vectors (2008) (0)
- Novel mouse glioma model using Cre-inducible lentiviral vectors reveals the broad existence of brain tumor stem/initiating cells in GBMs. (2007) (0)
- Fraud and deception in science. (2003) (0)
- Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme (2013) (0)
- Nerve growth factor induces neuron-like differentiation of an insulin-secreting pancreatic beta cell line ( pancreas / neural crest / endoderm / development / trk oncogene ) (2005) (0)
- LB-PO-854 LONG-TERM SAFETY STUDY OF LIVER-DIRECTED IN VIVO GENE TRANSFER WITH MOLONEY MURINE RETROVIRUSES AND LENTIVIRUSES IN WATANABE HERITABLE HYPERLIPIDEMIC RABBITS (2007) (0)
- Tissue-Specific Transgenesis by Lentiviral Vectors (2003) (0)
- EditorialMeetings, Meetings, and More Meetings (2002) (0)
- Direct involvement of the ubiquitin-conjugating enzyme Ubc 9 y Hus 5 in the degradation of I k B a (1997) (0)
- Autoregulation of IicBa activity (2005) (0)
- 269 Failure of bone marrow derived cells to replace injured livers (2003) (0)
- GENOME ORGANIZATION OF RETROVIRUSES IV. PHYSICAL MAPPING OF MURINE SARCOMA VIRUS AND HETERODUPLEX ANALYSIS OF RECOMBINANT MURINE LEUKEMIA VIRUSES (1979) (0)
- Comparative Study of Hematopoietic Lineage Potential of Ips Cells Derived From Two Mesodermal Cell Lineages (2011) (0)
- Lymphoid Regeneration fr om Gene-Corrected SCID-X 1 Subject-Derived iPSCs Graphical Abstract Highlights (2015) (0)
- RNA Interference Technology: siRNA delivery by lentiviral vectors: Design and applications (2005) (0)
- cB enhancer-binding complexes that do not contain NF-# cB are developmentally regulated in mammalian brain ( transcription / UV crosslinking / neural plasticity ) (2005) (0)
- , Vectors Long-Term Engraftment of NOD / SCID Mice by HIV Cells That Mediate + Transduction of Human (2009) (0)
- An Unfathomable Tragedy (2001) (0)
- Proto-oncogenes: Role in development, growth and differentiation (1986) (0)
- New editor of Molecular therapy (2002) (0)
- Constitutive phosphorylation of IicBa by casein kinase II (2005) (0)
- Dinorah Friedmann-Morvinski Induce Gliomas in Mice Dedifferentiation of Neurons and Astrocytes by Oncogenes Can (2012) (0)
- Models and Open Questions Pulmonary Surfactant Pathophysiology: Current (2015) (0)
- Abstract 5464: Pharmacologic activation of REV-ERBs is lethal in cancer and oncogene-induced senescence (2018) (0)
- A model with good CREdentials The sea snail Aplysia provides a relatively simple model system for studying both short-term and long-term memory; a known transcriptional mechanism is implicated in the establishment of the latter. (1994) (0)
- Abstract 4061: TRIM-NHL proteins: New potential targets for cancer therapy (2011) (0)
- References and Notes (2021) (0)
- Modification offos Proteins: Phosphorylation of c-fos, but Not v-fos, Is Stimulated by 12-Tetradecanoyl-Phorbol-13-Acetate (0)
- Abstract 524: Analysis of long non-coding RNA expression and function in a mouse model of glioblastoma (2014) (0)
- TRANSFORMATION – ANIMAL VIRUSES (1999) (0)
- Crystal Structure of Human Farnesyl Diphosphate Synthase in Complex with BPH-1222 (2014) (0)
- Genomic Editing of Stem Cells for Modeling and Therapy of Genetic Diseases (2015) (0)
- AIDS: are we doing enough? (2000) (0)
- Identification and molecular cloning of Moloney mouse sarcoma virus-specific sequences from uninfected mouse cells ( recombinant DNA / restriction endonuclease and Si mapping / electron microscopy ) (0)
- The DNA helix at 50. (2003) (0)
- 81. Hippocampal Gene Knockdown of BACE1 by Lentiviral Gene Transfer of siRNA Reduces Amyloid Pathology and Improves Memory Performance in APP Transgenic Mice (2006) (0)
- Abstract 2973: Mouse models of lung cancer mediated by lentiviral gene delivery (2014) (0)
- Science Translational Medicine Podcast: 19 November 2014 (2014) (0)
- Characterization of RACK7 as a Novel Factor Involved in BRCA1 Mutation Mediated Breast Cancer (2012) (0)
- Regulating the Master Regulator NF-_B: From Natural Strategies to Rationally Designed Superdrugs (2006) (0)
- Abstract PR3: NSCLC and SCLC mouse models mediated by lentiviral gene delivery (2012) (0)
- conditional gene modificatiol (2016) (0)
- Inhibition of astrocyte glutamate release by lentiviral gene transfer of tetanus toxin: Effects on neuronal circuitry in hippocampus (2003) (0)
- Structural features of growth factor receptors with oncogenic potential. (1986) (0)
- TAMI-12. CANCER-IMMUNE CELL INTERACTIONS DRIVE TRANSITIONS TO MESENCHYMAL-LIKE STATES IN GLIOBLASTOMA (2021) (0)
- Nucleotide sequence of a cloned murine leukemia virus DNA fragment. (1980) (0)
- Time varying causal network reconstruction of a mouse cell cycle (2019) (0)
- OTME-7. Cancer - immune cell interactions drive transitions to mesenchymal-like state in glioblastoma (2021) (0)
- Biogenesis of a transforming gene (1981) (0)
- Cancer Cell Previews Inflammatory Tales of Liver Cancer (2007) (0)
- Abstract 3703: Nanoparticle-induced targeted pro-apoptotic peptide in glioblastoma (2010) (0)
- Novel Lung Cancer Model Mediated by Lentiviral Gene Delivery (2011) (0)
- PNAS at 101: Heading into the next century (2016) (0)
- Triumph and Tragedy in Space (2003) (0)
- Nuclear oncoproteins: Target of signal transduction (1989) (0)
- 428. A Novel Approach for the Treatment of the Neurological Symptoms of MPS VII (Sly Disease) (2005) (0)
- Interview with Dr Verma. (2005) (0)
- Generation of multiciliated cells in functional airway epithelium from human iPSC (1094.5) (2014) (0)
- Musings for young scientists. (2004) (0)
- 56. Amelioration of Neurodegenerative and Neuropathological Alterations in a Transgenic Model of Alzheimer's Disease: Targeting BACE1 with Small Interfering RNAs (2005) (0)
- Politics and scientific publishing: noli me tangere. (2002) (0)
- Contradictions and extremes (2003) (0)
- Compositions et methodes destinees a cibler un polypeptide sur le systeme nerveux central (2003) (0)
- Just an appetizer (1995) (0)
- Abstract 70: Mouse models of human lung adenocarcinoma: Identification of potential tumor suppressors by functionalin vivoshRNA screening (2014) (0)
- Abstract SY41-01: Tumor-endothelial transdifferentiation (2012) (0)
- P4-091 Mechanisms of neuroprotection mediated by neprilysin in APP-transgenic mice (2006) (0)
- Abstract 3302: Antisense oligonucleotide depletion of the mitotic kinesin Eg5 by direct delivery to the brain could be a useful strategy for treating glioma tumors. (2013) (0)
- Simplifying the Direct Submission process (2014) (0)
- AIDS: no end in sight. (2004) (0)
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