Stephen Spiro

About

From Wikipedia

Stephen Spiro was a political activist known for his opposition against the Vietnam War and his advocacy of a consistent life ethic. Opposing the Vietnam war based on the theory of Just War, he objected to being conscripted, but as the law only allowed for conscientious objection to all wars, he was convicted of avoiding conscription and given a suspended sentence of five years. He was later pardoned by President Gerald Ford.

Published Works

• A non-haem iron centre in the transcription factor NorR senses nitric oxide
• The yjeB (nsrR) Gene of Escherichia coli Encodes a Nitric Oxide-Sensitive Transcriptional Regulator
• The FNR family of transcriptional regulators
• Regulators of bacterial responses to nitric oxide
• Adaptive responses to oxygen limitation inEscherichia coli
• Nitric oxide in bacteria: synthesis and consumption
• The FNR Modulon and FNR-Regulated Gene Expression
• The NorR Protein of Escherichia coli Activates Expression of the Flavorubredoxin Gene norV in Response to Reactive Nitrogen Species
• Two Conserved Glutamates in the Bacterial Nitric Oxide Reductase Are Essential for Activity but Not Assembly of the Enzyme
• The NsrR Regulon of Escherichia coli K-12 Includes Genes Encoding the Hybrid Cluster Protein and the Periplasmic, Respiratory Nitrite Reductase
• A Low-Redox Potential Heme in the Dinuclear Center of Bacterial Nitric Oxide Reductase: Implications for the Evolution of Energy-Conserving Heme−Copper Oxidases
• The purification of ammonia monooxygenase fromParacoccus denitrficans
• Detection of genes for periplasmic nitrate reductase in nitrate respiring bacteria and in community DNA
• Nitrite and nitric oxide reduction in Paracoccus denitrificans is under the control of NNR, a regulatory protein that belongs to the FNR family of transcriptional activators
• Nitric Oxide Is a Signal for NNR-Mediated Transcription Activation in Paracoccus denitrificans
• Purification of hydroxylamine oxidase fromThiosphaera pantotropha
• FNR and its role in oxygen-regulated gene expression inEscherichia coli
• DNA Binding Activity of the Escherichia coli Nitric Oxide Sensor NorR Suggests a Conserved Target Sequence in Diverse Proteobacteria
• Effect of carbon substrate and aeration on nitrate reduction and expression of the periplasmic and membrane-bound nitrate reductases in carbon-limited continuous cultures of Paracoccus denitrificans Pd1222
• Heterologous NNR-Mediated Nitric Oxide Signaling inEscherichia coli
• The identification of a periplasmic nitrate reductase inParacoccus denitrificans
• Point mutations in the DNA- and cNMP-binding domains of the homologue of the cAMP receptor protein (CRP) in Mycobacterium bovis BCG: implications for the inactivation of a global regulator and strain attenuation
• Heterologous expression of heterotrophic nitrification genes
• Detection of genes for membrane-bound nitrate reductase in nitrate-respiring bacteria and in community DNA
• The biochemical characterization of a novel non-haem-iron hydroxylamine oxidase from Paracoccus denitrificans GB17
• Spectral Properties of Bacterial Nitric-oxide Reductase
• The ferric uptake regulator of Pseudomonas aeruginosa has no essential cysteine residues and does not contain a structural zinc ion
• Transcription factor NNR from Paracoccus denitrificans is a sensor of both nitric oxide and oxygen: isolation of nnr* alleles encoding effector-independent proteins and evidence for a haem-based sensing mechanism
• Construction of a whole-cell gene reporter for the fluorescent bioassay of nitrate
• Identification of an assimilatory nitrate reductase in mutants of Paracoccus denitrificans GB17 deficient in nitrate respiration
• Transcription Factor FnrP from Paracoccus denitrificans Contains an Iron-Sulfur Cluster and Is Activated by Anoxia: Identification of Essential Cysteine Residues
• O-69 A randomized study of timing of thoracic irradiation in small cell lung cancer (SCLC) — study 8
• Isolation and characterisation of a strain of Pseudomonas putida that can express a periplasmic nitrate reductase
• The nitric oxide regulated nor promoter of Paracoccus denitrificans
• Stability of a 24-meric homopolymer: Comparative studies of assembly-defective mutants ofRhodobacter capsulatusbacterioferritin and the native protein
• Protein-Template-Driven Formation of Polynuclear Iron Species†
• Early Lung Cancer: screening and detection
• An FNR-dependent promoter fromEscherichia coliis active and anaerobically inducible inParacoccus denitrificans
• Anaerobic Growth of Paracoccus denitrificans Requires Cobalamin: Characterization ofcobK and cobJ Genes
• Isolation, characterisation and expression of the bacterioferritin gene ofRhodobacter capsulatus
• Hydroxylamine oxidation in heterotrophic nitrate-reducing soil bacteria and purification of a hydroxylamine-cytochromec oxidoreductase from aPseudomonas species
• A proposal for the DNA-binding specificity of the FNR protein of Escherichia coli
• A randomised comparison of radical radiotherapy with or without chemotherapy for patients with non-small cell lung cancer: Results from the Big Lung Trial
• Are We Achieving the Current Waiting Time Targets in Lung Cancer Treatment?
• Hydroxylamine oxidation in heterotrophic nitrate-reducing soil bacteria and purification of a hydroxylamine-cytochrome c oxidoreductase from a Pseudomonas species
• P010. The nitric oxide response of Escherichia coli
• Interactions of heme and other metal ion complexes with the bacterial Fe-uptake regulatory protein and with bacterioferritin
• O-60 The big lung trial quality of life study: Determining the effect of cisplatin-based chemotherapy for supportive care patients with non-small cell lung cancer (NSCLC)
• CHAPTER 13. Regulation of Denitrification
• Heterotrophic nitrification in Paracoccus denitrificans
• Regulation of fnr gene expression in Escherichia coli and over-production of the FNR protein
• Transcriptional regulation of denitrification genes in Paracoccus denitrificans
• Spectral properties of bacterial nitric oxide reductase
• A randomised controlled trial of surveillance for the early detection of lung cancer in an at risk group
• Faculty Opinions recommendation of Insights into signal transduction involving PAS domain oxygen-sensing heme proteins from the X-ray crystal structure of Escherichia coli Dos heme domain (Ec DosH).
• Faculty Opinions recommendation of Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain.
• Faculty Opinions recommendation of Staphylococcal NreB: an O(2)-sensing histidine protein kinase with an O(2)-labile iron-sulphur cluster of the FNR type.
• Faculty Opinions recommendation of Long-term anaerobic survival of the opportunistic pathogen Pseudomonas aeruginosa via pyruvate fermentation.
• Faculty Opinions recommendation of Identification of a quinone-sensitive redox switch in the ArcB sensor kinase.
• Faculty Opinions recommendation of Genomic studies with Escherichia coli MelR protein: applications of chromatin immunoprecipitation and microarrays.
• Faculty Opinions recommendation of An unusual tryptophanyl tRNA synthetase interacts with nitric oxide synthase in Deinococcus radiodurans.
• Faculty Opinions recommendation of Structural insights into the activity of enhancer-binding proteins.
• Faculty Opinions recommendation of A transcriptional response to singlet oxygen, a toxic byproduct of photosynthesis.
• Faculty Opinions recommendation of Signal peptide-chaperone interactions on the twin-arginine protein transport pathway.
• Faculty Opinions recommendation of NmlR of Neisseria gonorrhoeae: a novel redox responsive transcription factor from the MerR family.
• Faculty Opinions recommendation of Defining genes in the genome of the hyperthermophilic archaeon Pyrococcus furiosus: implications for all microbial genomes.
• Faculty Opinions recommendation of ClpXP-dependent proteolysis of FNR upon loss of its O2-sensing [4Fe-4S] cluster.
• Faculty Opinions recommendation of Dissimilatory metabolism of nitrogen oxides in bacteria: comparative reconstruction of transcriptional networks.
• Faculty Opinions recommendation of Genomic analysis of LexA binding reveals the permissive nature of the Escherichia coli genome and identifies unconventional target sites.
• Faculty Opinions recommendation of Studies of the distribution of Escherichia coli cAMP-receptor protein and RNA polymerase along the E. coli chromosome.
• Faculty Opinions recommendation of Novel organic hydroperoxide-sensing and responding mechanisms for OhrR, a major bacterial sensor and regulator of organic hydroperoxide stress.
• Faculty Opinions recommendation of Biodegradation of 3-nitrotyrosine by Burkholderia sp. strain JS165 and Variovorax paradoxus JS171.
• Faculty Opinions recommendation of Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.
• Faculty Opinions recommendation of The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation.
• Faculty Opinions recommendation of IscR-dependent gene expression links iron-sulphur cluster assembly to the control of O2-regulated genes in Escherichia coli.
• Faculty Opinions recommendation of Global gene expression profiling of the asymptomatic bacteriuria Escherichia coli strain 83972 in the human urinary tract.
• Faculty Opinions recommendation of IscR acts as an activator in response to oxidative stress for the suf operon encoding Fe-S assembly proteins.
• Faculty Opinions recommendation of Adaptive response of Yersinia pestis to extracellular effectors of innate immunity during bubonic plague.
• Faculty Opinions recommendation of Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp.
• Faculty Opinions recommendation of Escherichia coli transcriptome dynamics during the transition from anaerobic to aerobic conditions.
• Faculty Opinions recommendation of MiST: a microbial signal transduction database.
• Faculty Opinions recommendation of Transcription factor distribution in Escherichia coli: studies with FNR protein.
• Faculty Opinions recommendation of Involvement of a periplasmic protein kinase in DNA strand break repair and homologous recombination in Escherichia coli.
• Faculty Opinions recommendation of How gene order is influenced by the biophysics of transcription regulation.
• Faculty Opinions recommendation of Blue-light-activated histidine kinases: two-component sensors in bacteria.
• Faculty Opinions recommendation of DosT and DevS are oxygen-switched kinases in Mycobacterium tuberculosis.
• Faculty Opinions recommendation of The archaeon Methanosarcina acetivorans contains a protein disulfide reductase with an iron-sulfur cluster.
• Faculty Opinions recommendation of Shewanella oneidensis MR-1 H-NOX regulation of a histidine kinase by nitric oxide.
• Faculty Opinions recommendation of CGFS-type monothiol glutaredoxins from the cyanobacterium Synechocystis PCC6803 and other evolutionary distant model organisms possess a glutathione-ligated [2Fe-2S] cluster.

Other Resources

• en.wikipedia.org

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Georgia Tech

Public research university in Atlanta, Georgia, United States

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Fairleigh Dickinson University

American university

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University of East Anglia

University in Norwich, England

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University of Sheffield

University in Sheffield, United Kingdom

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University of Texas at Dallas

Public university in Dallas, Texas

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