Alfonso Valencia
Spanish biologist
Alfonso Valencia's AcademicInfluence.com Rankings
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Biology
Alfonso Valencia's Degrees
- PhD Biotechnology University of Barcelona
- Masters Bioinformatics University of Valencia
- Bachelors Biology University of Valencia
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Why Is Alfonso Valencia Influential?
(Suggest an Edit or Addition)Areas of Specialization: Computational Biology
Alfonso Valencia is director of the Spanish National Bioinformatics Institute and the Life Sciences department at Barcelona Supercomputing Center. He is a professor for the Catalan Institution for Research and Advanced Studies and former president of the International Society for Computational Biology. He earned his PhD in molecular biology from the Autonomous University of Madrid before completing a postdoctoral fellowship at the European Molecular Biology Laboratory.
His scientific research has focused on biomedical systems, using computational biology and bioinformatics methods. Valencia’s research group has produced systems for protein networks, systems biology, text and data mining, protein structure prediction, and more…with useful applications in cancer genomics, disease comorbidity, and epigenetics. These areas together form a basis for personalized medicine with the use of AI and computer modeling.
Valencia has also provided substantial leadership in his field, with positions as vice president and president of the International Society for Computational Biology and as a founding member of the organization.
He has been active in international consortia for his field of study, including the International Cancer Genome Consortium, the International Rare Diseases Research Consortium, Genecode/ENCODE, and the International Human Epigenomics Consortium. Valencia is also a co-executive editor for the journal, Bioinformatics.
Featured in Top Influential Biologists Today
According to Wikipedia, Alfonso Valencia is a Spanish biologist, ICREA Professor, current director of the Life Sciences department at Barcelona Supercomputing Center. and of Spanish National Bioinformatics Institute . From 2015-2018, he was President of the International Society for Computational Biology. His research is focused on the study of biomedical systems with computational biology and bioinformatics approaches.
Alfonso Valencia's Published Works
Published Works
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (2007) (5196)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Comprehensive molecular characterization of mitochondrial genomes in human cancers (2017) (197)
- Alternative Splicing (2019) (193)
- Inverse and Direct Cancer Comorbidity in People with Central Nervous System Disorders: A Meta-Analysis of Cancer Incidence in 577,013 Participants of 50 Observational Studies (2014) (144)
- Detection of SARS-CoV-2 in a cat owned by a COVID-19−affected patient in Spain (2020) (133)
- Towards FAIR principles for research software (2020) (132)
- No paradox, no progress: inverse cancer comorbidity in people with other complex diseases. (2011) (130)
- COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (107)
- Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare (2020) (105)
- Big data analytics for personalized medicine. (2019) (102)
- Integrative pathway enrichment analysis of multivariate omics data (2018) (96)
- Perspectives on ENCODE (2020) (79)
- SARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity (2021) (67)
- Neoantigen prediction and computational perspectives towards clinical benefit: Recommendations from the ESMO Precision Medicine Working Group. (2020) (64)
- GA4GH: International policies and standards for data sharing across genomic research and healthcare (2021) (62)
- Stable neutralizing antibody levels 6 months after mild and severe COVID-19 episodes (2021) (62)
- Leveraging European infrastructures to access 1 million human genomes by 2022 (2019) (60)
- Legacy data sharing to improve drug safety assessment: the eTOX project (2017) (52)
- Identifying ELIXIR Core Data Resources. (2016) (51)
- Improving data and knowledge management to better integrate health care and research (2013) (45)
- Sex and gender differences and biases in artificial intelligence for biomedicine and healthcare. (2020) (41)
- Sex differences in oncogenic mutational processes (2019) (41)
- Identification of Plitidepsin as Potent Inhibitor of SARS-CoV-2-Induced Cytopathic Effect After a Drug Repurposing Screen (2020) (37)
- Lessons Learned: Recommendations for Establishing Critical Periodic Scientific Benchmarking (2017) (29)
- The bio.tools registry of software tools and data resources for the life sciences (2019) (28)
- Alzheimer's Disease and Cancer: Current Epidemiological Evidence for a Mutual Protection (2014) (27)
- Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in golden Syrian hamster (2021) (26)
- COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms (2021) (24)
- Pigs are not susceptible to SARS‐CoV‐2 infection but are a model for viral immunogenicity studies (2020) (23)
- Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (22)
- Stable neutralizing antibody levels six months after mild and severe COVID-19 episode (2020) (20)
- Identifying ELIXIR Core Data Resources (2017) (20)
- Simulating SARS-CoV-2 epidemics by region-specific variables and modeling contact tracing app containment (2021) (19)
- Patient-specific Boolean models of signalling networks guide personalised treatments (2022) (18)
- Transcriptomic and Genetic Associations between Alzheimer’s Disease, Parkinson’s Disease, and Cancer (2021) (18)
- Mortality in Persons With Autism Spectrum Disorder or Attention-Deficit/Hyperactivity Disorder (2022) (18)
- Piglets inoculated by different routes are not susceptible to SARS-CoV-2, but those inoculated parenterally were immunized against the virus. (2020) (18)
- Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer (2018) (16)
- Pan-cancer study of heterogeneous RNA aberrations (2017) (16)
- Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships (2020) (15)
- Cancer and central nervous system disorders: protocol for an umbrella review of systematic reviews and updated meta-analyses of observational studies (2017) (14)
- Artificial Intelligence–Aided Precision Medicine for COVID-19: Strategic Areas of Research and Development (2021) (13)
- The eTRANSAFE Project on Translational Safety Assessment through Integrative Knowledge Management: Achievements and Perspectives (2021) (13)
- Search for SARS-CoV-2 inhibitors in currently approved drugs to tackle COVID-19 pandemia (2020) (12)
- Pretrained Biomedical Language Models for Clinical NLP in Spanish (2022) (12)
- Systems biology at the giga-scale: Large multiscale models of complex, heterogeneous multicellular systems (2021) (12)
- ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing (2016) (11)
- COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (11)
- Risk of mortality among children, adolescents, and adults with autism spectrum disorder or attention deficit hyperactivity disorder and their first-degree relatives: a protocol for a systematic review and meta-analysis of observational studies (2017) (10)
- Molecular Inverse Comorbidity between Alzheimer’s Disease and Lung Cancer: New Insights from Matrix Factorization (2019) (10)
- ISCB’s Initial Reaction to The New England Journal of Medicine Editorial on Data Sharing (2016) (10)
- Association of Anorexia Nervosa With Risk of Cancer (2019) (8)
- COVID‐19 Disease Map, a computational knowledge repository of virus‐host interaction mechanisms (2021) (8)
- Assessing the accuracy of contact and distance predictions in CASP14 (2021) (8)
- Interactive Extreme: Scale Analytics Towards Battling Cancer (2019) (8)
- A catalogue of 863 Rett-syndrome-causing MECP2 mutations and lessons learned from data integration (2021) (8)
- Anorexia nervosa and cancer: a protocol for a systematic review and meta-analysis of observational studies (2017) (7)
- COVID-19 Flow-Maps an open geographic information system on COVID-19 and human mobility for Spain (2021) (7)
- Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (7)
- How to Design AI-Driven Clinical Trials in Nuclear Medicine. (2020) (7)
- Artificial intelligence in cancer research: learning at different levels of data granularity (2021) (7)
- Reproducing SARS-CoV-2 epidemics byregion-specific variables and modeling contacttracing App containment (2020) (6)
- Perspectives on emerging technologies, personalised medicine, and clinical research for cancer control in Latin America and the Caribbean. (2021) (6)
- BioFVM-X: An MPI+OpenMP 3-D Simulator for Biological Systems (2021) (5)
- Parallel model exploration for tumor treatment simulations (2021) (5)
- Optimizing Dosage-Specific Treatments in a Multi-Scale Model of a Tumor Growth (2021) (5)
- The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research (2020) (4)
- Evaluating the policy of closing bars and restaurants in Cataluña and its effects on mobility and COVID19 incidence (2021) (4)
- PhysiBoSS 2.0: a sustainable integration of stochastic Boolean and agent-based modelling frameworks (2022) (4)
- Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022 (2019) (4)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight (2020) (4)
- Pre-clinical search of SARS-CoV-2 inhibitors and their combinations in approved drugs to tackle COVID-19 pandemic (2020) (3)
- Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs (2020) (3)
- SmartRNASeqCaller: improving germline variant calling from RNAseq (2019) (3)
- COVID-19 Flow-Maps an open geographic information system on COVID-19 and human mobility for Spain (2021) (3)
- Education and Research Infrastructures (2011) (3)
- SARS-CoV-2 B.1.351 (beta) variant shows enhanced infectivity in K18-hACE2 transgenic mice and expanded tropism to wildtype mice compared to B.1 variant (2021) (3)
- How to improve data and knowledge management to better integrate healthcare and research (2013) (3)
- PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data (2018) (2)
- The Gene Regulation Knowledge Commons: The action area of GREEKC. (2021) (2)
- Patient-specific Boolean models of signaling networks guide personalized treatments (2021) (2)
- Protection against reinfection with D614- or G614-SARS-CoV-2 isolates in hamsters (2021) (2)
- The multilayer community structure of medulloblastoma (2021) (2)
- Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx (2016) (2)
- A versatile and interoperable computational framework for the analysis and modeling of COVID-19 disease mechanisms (2022) (1)
- Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower (2020) (1)
- The bio.tools registry of software tools and data resources for the life sciences (2019) (1)
- Author Correction: Integrative pathway enrichment analysis of multivariate omics data (2020) (1)
- ELIXIR Implementation Study End Report: Remote real-time visualization of human rare disease genomics data (RD-Connect) stored at the EGA (2018) (1)
- Author Correction: Pan-cancer analysis of whole genomes (2023) (1)
- Association of Anorexia NervosaWith Risk of Cancer A Systematic Review andMeta-analysis (2019) (1)
- Author Correction: DOME: recommendations for supervised machine learning validation in biology (2021) (1)
- Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes (2020) (1)
- A computational approach inspired by simulated annealing to study the stability of protein interaction networks in cancer and neurological disorders (2015) (1)
- Transcriptional dissection of pancreatic tumors engrafted in mice (2014) (1)
- ISMB 2008 Organization (2008) (0)
- Algorithmic complexity in Computational Biology (2018) (0)
- Scientific Communities in OpenEBench (2020) (0)
- OpenEBench scientific benchmarking (2019) (0)
- A multilayer network approach to elucidate severity in Congenital Myasthenic Syndromes (2019) (0)
- The Spanish National Bioinformatics Institute (INB/ELIXIR-ES) (2019) (0)
- COVID-19 and Beyond: A Call for Action and Audacious Solidarity to All the Citizens and Nations, It Is Humanity’s Fight (2020) (0)
- Interpreting molecular similarity between patients as a determinant of disease comorbidity relationships (2020) (0)
- Benchmarking data visualization (2018) (0)
- Editorial (2008) (0)
- ECCB 2012 Organization (2012) (0)
- Usefulness of pGALS as a screening test in children and adolescents in Colombia. Cross-sectional study (2020) (0)
- ECCB2022: the 21st European Conference on Computational Biology. (2022) (0)
- COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (0)
- Analysis of electronic health records from three distinct and large populations reveals high prevalence and biases in the co-administration of drugs known to interact (2023) (0)
- KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily (2016) (0)
- Design and methodological characteristics of studies using observational routinely collected health data for investigating the link between cancer and neurodegenerative diseases: protocol for a meta-research study (2022) (0)
- Artificial Intelligence–Aided Precision Medicine for COVID-19: Strategic Areas of Research and Development (Preprint) (2020) (0)
- Author’s response to reviews Title: Risk of mortality among children, adolescents and adults with autism spectrum disorder or attention deficit hyperactivity disorder and their first-degree relatives: a protocol for a systematic review and meta-analysis of observational studies (2017) (0)
- Author Correction: Inferring structural variant cancer cell fraction (2022) (0)
- ISCB’s initial reaction to New England Journal of Medicine editorial on data sharing (2016) (0)
- Patient stratification reveals the molecular basis of disease comorbidities (2021) (0)
- Deep and cognitive learning applied to Precision Medicine: the initial experiments linking (epi)genome to phenotypes-disease characteristics (2017) (0)
- OpenEBench. TCGA: A community-led benchmarking use case. (2020) (0)
- Engaging European society at the forefront of cancer research and care. (2023) (0)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: 3 approved with reservations] (2021) (0)
- 3D chromatin connectivity underlies replication origin efficiency in mouse embryonic stem cells (2022) (0)
- Rare disease research workflow using multilayer networks elucidates the molecular determinants of severity in Congenital Myasthenic Syndromes (2023) (0)
- Reconstructing protein interactions at enhancer-promoter regions in prostate cancer (2022) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- Genome-wide analysis of Pax8 binding provides new insights into thyroid functions (2012) (0)
- COVID-19 and beyond: a call for action and audacious solidarity to all the citizens and nations, it is humanity’s fight [version 1; peer review: awaiting peer review] (2020) (0)
- The Evolution of Local Energetic Frustration in Protein Families (2023) (0)
- Molecular COPD Heterogeneity Uncovered by Multi-layer Network Analysis (2023) (0)
- Author Correction: The evolutionary history of 2,658 cancers (2023) (0)
- Compute infrastructure for ELXIR-ES/INB (2018) (0)
- Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
- Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution (2022) (0)
- Graph analytics for phenome-genome associations inference (2019) (0)
- A user guide for the online exploration and visualization of PCAWG data (2020) (0)
- Author Correction: Perspectives on ENCODE (2022) (0)
- Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types (2017) (0)
- 863 different causes of Rett syndrome and lessons learned from data integration. (2020) (0)
- Integrating epigenomic data and 3D genomic structure with a new measure of chromatin assortativity (2016) (0)
- Microsoft Word-PKL12-GlcNAck (2001) (0)
- Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies (2016) (0)
- Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia (2015) (0)
- Erratum to: The UBC-40 Urothelial Bladder Cancer Cell Line Index: a genomic resource for functional studies (2015) (0)
- The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies (2015) (0)
- TITLE : Search for SARS-CoV-2 inhibitors in currently approved drugs to tackle COVID-19 pandemia Mode of Action Previous Clinical Use (2020) (0)
- Patient-specific Boolean models of signalling (0)
- Author Correction: COVID-19 Disease Map, building a computational repository of SARS-CoV-2 virus-host interaction mechanisms (2020) (0)
- OpenEBench Widgets Gallery (2018) (0)
- GOPHER, an HPC Framework for Large Scale Graph Exploration and Inference (2020) (0)
- Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics (2012) (0)
- A molecular hypothesis to explain direct and inverse co-morbidities between Alzheimer’s Disease, Glioblastoma and Lung cancer (2017) (0)
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