Christiane Nüsslein-Volhard
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German biologist
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Christiane Nüsslein-Volhardbiology Degrees
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Developmental Biology
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Christiane Nüsslein-Volhard's Degrees
- PhD Biology University of Tübingen
Why Is Christiane Nüsslein-Volhard Influential?
(Suggest an Edit or Addition)According to Wikipedia, Christiane Nüsslein-Volhard is a German developmental biologist and a 1995 Nobel Prize in Physiology or Medicine laureate. She is the only woman from Germany to have received a Nobel Prize in the sciences.
Christiane Nüsslein-Volhard's Published Works
Published Works
- Mutations affecting segment number and polarity in Drosophila (1980) (4186)
- The zebrafish reference genome sequence and its relationship to the human genome (2013) (3401)
- The identification of genes with unique and essential functions in the development of the zebrafish, Danio rerio. (1996) (1688)
- The origin of pattern and polarity in the Drosophila embryo (1992) (1336)
- The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner (1988) (997)
- A gradient of bicoid protein in Drosophila embryos (1988) (967)
- Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster (1984) (739)
- The role of localization of bicoid RNA in organizing the anterior pattern of the Drosophila embryo. (1988) (738)
- Large-scale mutagenesis in the zebrafish: in search of genes controlling development in a vertebrate (1994) (735)
- Zebrafish : a practical approach (2002) (732)
- Establishment of dorsal-ventral polarity in the Drosophila embryo: Genetic studies on the role of the Toll gene product (1985) (690)
- The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. (1992) (684)
- staufen, a gene required to localize maternal RNAs in the Drosophila egg (1991) (660)
- no tail (ntl) is the zebrafish homologue of the mouse T (Brachyury) gene. (1994) (647)
- A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo (1989) (645)
- Determination of anteroposterior polarity in Drosophila. (1987) (634)
- Establishment of dorsal-ventral polarity in the drosophila embryo: The induction of polarity by the Toll gene product (1985) (626)
- The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo (1989) (612)
- Genes controlling and mediating locomotion behavior of the zebrafish embryo and larva. (1996) (606)
- Mutations affecting somite formation and patterning in the zebrafish, Danio rerio. (1996) (550)
- Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo (2008) (518)
- Abdominal segmentation, pole cell formation, and embryonic polarity require the localized activity of oskar, a maternal gene in drosophila (1986) (466)
- Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner (1994) (449)
- Mutations affecting the cardiovascular system and other internal organs in zebrafish. (1996) (447)
- Zebrafish pigmentation mutations and the processes of neural crest development. (1996) (437)
- fork head domain genes in zebrafish (1998) (437)
- A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor (2003) (424)
- Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. (1996) (421)
- Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid (1986) (403)
- Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen (1989) (402)
- Zebrafish vasa RNA but Not Its Protein Is a Component of the Germ Plasm and Segregates Asymmetrically before Germline Specification (2000) (382)
- The maternal gene nanos has a central role in posterior pattern formation of the Drosophila embryo. (1991) (382)
- Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain. (1996) (360)
- Origin and development of the zebrafish endoderm. (1999) (352)
- Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster (2004) (347)
- Mutations affecting development of the zebrafish inner ear and lateral line. (1996) (335)
- Jaw and branchial arch mutants in zebrafish I: branchial arches. (1996) (334)
- dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. (1996) (333)
- Information for the dorsal–ventral pattern of the Drosophila embryo is stored as maternal mRNA (1984) (332)
- Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. (1997) (331)
- Control of her1 expression during zebrafish somitogenesis by a delta-dependent oscillator and an independent wave-front activity. (2000) (327)
- Keeping and raising zebrafish (2002) (323)
- Expression of zebrafish goosecoid and no tail gene products in wild-type and mutant no tail embryos. (1994) (319)
- Multiple steps in the localization of bicoid RNA to the anterior pole of the Drosophila oocyte. (1989) (314)
- Mutations affecting neurogenesis and brain morphology in the zebrafish, Danio rerio. (1996) (313)
- Migration and Function of a Glial Subtype in the Vertebrate Peripheral Nervous System (2002) (307)
- Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerio. (1996) (302)
- The Drosophila gene torso encodes a putative receptor tyrosine kinase (1989) (300)
- Genetic Analysis of Vertebrate Sensory Hair Cell Mechanosensation: the Zebrafish Circler Mutants (1998) (298)
- Zebrafish mutations affecting retinotectal axon pathfinding. (1996) (289)
- Mutations affecting development of the midline and general body shape during zebrafish embryogenesis. (1996) (281)
- hunchback, a gene required for segmentation of an anterior and posterior region of the Drosophila embryo. (1987) (278)
- A radiation hybrid map of the zebrafish genome (1999) (275)
- Characterization of zebrafish mutants with defects in embryonic hematopoiesis. (1996) (274)
- A fate map for the larval epidermis of Drosophila melanogaster: localized cuticle defects following irradiation of the blastoderm with an ultraviolet laser microbeam. (1979) (273)
- Zebrafish pea3 and erm are general targets of FGF8 signaling (2001) (269)
- The control of cell fate along the dorsal-ventral axis of the Drosophila embryo. (1991) (267)
- her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis. (2002) (264)
- The molecular motor dynein is involved in targeting Swallow and bicoid RNA to the anterior pole of Drosophila oocytes (2000) (259)
- Precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system (2014) (258)
- Jaw and branchial arch mutants in zebrafish II: anterior arches and cartilage differentiation. (1996) (258)
- A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo. (1988) (249)
- Germ line control of female sex determination in zebrafish. (2008) (248)
- Function of torso in determining the terminal anlagen of the Drosophila embryo (1988) (236)
- RNA–RNA interaction is required for the formation of specific bicoid mRNA 3′ UTR–STAUFEN ribonucleoprotein particles (1997) (231)
- Mutations affecting the formation of the notochord in the zebrafish, Danio rerio. (1996) (231)
- Genetic analysis of fin formation in the zebrafish, Danio rerio. (1996) (230)
- The endoderm plays an important role in patterning the segmented pharyngeal region in zebrafish (Danio rerio). (2000) (228)
- cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the IκB gene family of vertebrates (1992) (218)
- Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster (1984) (202)
- Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster (2005) (198)
- High-frequency germ-line transmission of plasmid DNA sequences injected into fertilized zebrafish eggs. (1991) (197)
- Genetic dissection of the retinotectal projection. (1996) (187)
- Zebrafish eda and edar Mutants Reveal Conserved and Ancestral Roles of Ectodysplasin Signaling in Vertebrates (2008) (185)
- The dissociation of nuclear and centrosomal division in gnu, a mutation causing giant nuclei in Drosophila (1986) (179)
- cactus, a maternal gene required for proper formation of the dorsoventral morphogen gradient in Drosophila embryos. (1991) (177)
- Mutations affecting xanthophore pigmentation in the zebrafish, Danio rerio. (1996) (175)
- Axon Sorting in the Optic Tract Requires HSPG Synthesis by ext2 (dackel) and extl3 (boxer) (2004) (173)
- Zebrafish Stripes as a Model for Vertebrate Colour Pattern Formation (2015) (171)
- Mutations affecting pigmentation and shape of the adult zebrafish (1996) (170)
- Iridophores and their interactions with other chromatophores are required for stripe formation in zebrafish (2013) (167)
- Drosophila Knickkopf and Retroactive are needed for epithelial tube growth and cuticle differentiation through their specific requirement for chitin filament organization (2006) (167)
- Determination of the embryonic axes of Drosophila. (1991) (166)
- The zebrafish epiboly mutants. (1996) (165)
- Neural degeneration mutants in the zebrafish, Danio rerio. (1996) (164)
- Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg (1992) (164)
- Localized requirement for torso-like expression in follicle cells for development of terminal anlagen of the Drosophila embryo (1990) (163)
- Mutations disrupting the ordering and topographic mapping of axons in the retinotectal projection of the zebrafish, Danio rerio. (1996) (162)
- Large scale genetics in a small vertebrate, the zebrafish. (1996) (149)
- Formation of the adult pigment pattern in zebrafish requires leopard and obelix dependent cell interactions (2003) (147)
- The expression of a zebrafish gene homologous to Drosophila snail suggests a conserved function in invertebrate and vertebrate gastrulation. (1993) (147)
- A dorso-ventral shift of embryonic primordia in a new maternal-effect mutant of Drosophila (1980) (144)
- Genes affecting the segmental subdivision of the Drosophila embryo. (1985) (143)
- Involvement of the pumilio gene in the transport of an abdominal signal in the Drosophila embryo (1987) (141)
- The function of silberblick in the positioning of the eye anlage in the zebrafish embryo. (1997) (139)
- Oligomerisation of Tube and Pelle leads to nuclear localisation of Dorsal (1999) (136)
- Bioelectric Signaling Regulates Size in Zebrafish Fins (2014) (134)
- Of flies and fishes. (1994) (132)
- Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo (1994) (130)
- Autonomous determination of anterior structures in the early Drosophila embryo by the bicoid morphogen. (1990) (129)
- A Sponge-like Structure Involved in the Association and Transport of Maternal Products during Drosophila Oogenesis (1997) (128)
- On the embryonic origin of adult melanophores: the role of ErbB and Kit signalling in establishing melanophore stem cells in zebrafish (2013) (127)
- An Evolutionary Conserved Region in the vasa 3′UTR Targets RNA Translation to the Germ Cells in the Zebrafish (2002) (126)
- A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila (1996) (125)
- Maternal genes required for the anterior localization of bicoid activity in the embryo of Drosophila (1987) (124)
- Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. (1992) (124)
- Towing of sensory axons by their migrating target cells in vivo (2004) (120)
- Fishing for genes controlling development. (1996) (119)
- Multiple extracellular activities in Drosophila egg perivitelline fluid are required for establishment of embryonic dorsal-ventral polarity (1992) (115)
- Two distinct cell populations in the floor plate of the zebrafish are induced by different pathways. (2000) (115)
- Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity. (1999) (113)
- Duplication of fgfr1 Permits Fgf Signaling to Serve as a Target for Selection during Domestication (2009) (113)
- Local reorganization of xanthophores fine-tunes and colors the striped pattern of zebrafish (2014) (109)
- The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote (2003) (108)
- Proliferation, dispersal and patterned aggregation of iridophores in the skin prefigure striped colouration of zebrafish (2014) (108)
- Slc45a2 and V‐ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease (2013) (107)
- A mutation in the zebrafish maternal-effect gene nebel affects furrow formation and vasa RNA localization (1999) (105)
- An F1 Genetic Screen for Maternal-Effect Mutations Affecting Embryonic Pattern Formation in Drosophila melanogaster (2004) (99)
- Genetic lineage labeling in zebrafish uncovers novel neural crest contributions to the head, including gill pillar cells (2013) (97)
- Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences (1989) (97)
- Myosin-V Regulates oskar mRNA Localization in the Drosophila Oocyte (2009) (90)
- Mutational approaches to studying embryonic pattern formation in the zebrafish. (1993) (89)
- Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish (2014) (81)
- Bazooka is required for polarisation of the Drosophila anterior-posterior axis (2010) (78)
- Zebrafish segmentation and pair-rule patterning. (1998) (77)
- Lgl2 Executes Its Function as a Tumor Suppressor by Regulating ErbB Signaling in the Zebrafish Epidermis (2009) (75)
- The Drosophila SHC adaptor protein is required for signaling by a subset of receptor tyrosine kinases. (2000) (72)
- Gradients that organize embryo development. (1996) (71)
- Pigment Cell Progenitors in Zebrafish Remain Multipotent through Metamorphosis. (2016) (71)
- Segmental organisation of the head in the embryo of Drosophila melanogaster (1986) (71)
- Large-scale mapping of mutations affecting zebrafish development (2007) (70)
- γ-Tubulin37C and γ-tubulin ring complex protein 75 Are Essential for bicoid RNA Localization during Drosophila Oogenesis (2002) (69)
- transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival (2013) (69)
- Manipulating the anteroposterior pattern of the Drosophila embryo. (1986) (67)
- Lgl2 and E-cadherin act antagonistically to regulate hemidesmosome formation during epidermal development in zebrafish (2009) (65)
- ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration. (2009) (65)
- The zebrafish early arrest mutants. (1996) (63)
- The functional domains of the Drosophila morphogen dorsal: evidence from the analysis of mutants. (1992) (62)
- transparent, a gene affecting stripe formation in Zebrafish, encodes the mitochondrial protein Mpv17 that is required for iridophore survival (2013) (62)
- The Developmental Genetics of Vertebrate Color Pattern Formation: Lessons from Zebrafish. (2016) (62)
- The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account. (2016) (60)
- The zebrafish issue of Development (2012) (60)
- The γTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline (2006) (60)
- 123 Neural degeneration mutants in the zebrafish, danio rerio (1996) (58)
- Endothelin signalling in iridophore development and stripe pattern formation of zebrafish (2014) (56)
- ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells (2017) (54)
- Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration. (2009) (53)
- Retroactive, a membrane‐anchored extracellular protein related to vertebrate snake neurotoxin‐like proteins, is required for cuticle organization in the larva of Drosophila melanogaster (2005) (52)
- The genetics of the dorsal-Bicaudal-D region of Drosophila melanogaster. (1986) (51)
- Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning (2015) (50)
- Scales of fish arise from mesoderm (2013) (49)
- Identification of recessive maternal‐effect mutations in the zebrafish using a gynogenesis‐based method (2004) (49)
- Axis determination in insect embryos. (1989) (49)
- How fish color their skin: A paradigm for development and evolution of adult patterns (2017) (48)
- Zebrafish Leucocyte tyrosine kinase controls iridophore establishment, proliferation and survival (2016) (48)
- chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. (2005) (48)
- Krapfen/dMyd88 is required for the establishment of dorsoventral pattern in the Drosophila embryo (2003) (42)
- Somitogenesis in zebrafish. (2000) (42)
- Heterotypic interactions regulate cell shape and density during color pattern formation in zebrafish (2016) (40)
- Homotypic cell competition regulates proliferation and tiling of zebrafish pigment cells during colour pattern formation (2016) (40)
- Disulfide cross-linking in crude embryonic lysates reveals three complexes of the Drosophila morphogen dorsal and its inhibitor cactus. (1994) (38)
- The identification of genes involved in the evolution of color patterns in fish (2019) (36)
- spadetail-dependent cell compaction of the dorsal zebrafish blastula. (1998) (36)
- Isolation and cytogenetic characterization of zebrafish meiotic prophase I mutants (2011) (35)
- Spermidine, but not spermine, is essential for pigment pattern formation in zebrafish (2016) (34)
- A dominant mutation in tyrp1A leads to melanophore death in zebrafish (2014) (34)
- Drosophila p24 homologues eclair and baiser are necessary for the activity of the maternally expressed Tkv receptor during early embryogenesis (2004) (33)
- Genetic analysis of pattern-formation in the embryo ofDrosophila melanogaster (1977) (30)
- Axis determination in the Drosophila embryo. (1989) (28)
- Gamma-tubulin37C and gamma-tubulin ring complex protein 75 are essential for bicoid RNA localization during drosophila oogenesis. (2002) (26)
- The Cellular Basis of Morphogenetic Change Group Report (1982) (25)
- Zebrafish (Danio rerio) Genome and Genetics (2006) (24)
- A conserved axon type hierarchy governing peripheral nerve assembly (2014) (23)
- Response to Comment on “Local reorganization of xanthophores fine-tunes and colors the striped pattern of zebrafish” (2015) (22)
- Coming to Life: How Genes Drive Development (2006) (20)
- The Identification of Genes Controlling Development in Flies and Fishes (Nobel Lecture) (1996) (18)
- Gain-of-function mutations in Aqp3a influence zebrafish pigment pattern formation through the tissue environment (2017) (17)
- Developmental genetics with model organisms (2022) (15)
- Galanin Signaling in the Brain Regulates Color Pattern Formation in Zebrafish (2019) (13)
- Evolution of the potassium channel gene Kcnj13 underlies colour pattern diversification in Danio fish (2020) (12)
- The bicoid morphogen papers (I): Account from CNV (2004) (12)
- Developmental biology: Embryology goes fishing (1986) (12)
- SUMMARY her 1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis (2002) (11)
- The Toll gene in Drosophila pattern formation. (2021) (11)
- A rough guide to Drosophila mating (2013) (11)
- HALF-TETRAD ANALYSIS IN ZEBRAFISH: MAPPING THE ROS MUTATION AND THE CENTROMERE OF LINKAGE GROUP I (1998) (11)
- Obituary: Hans Meinhardt (1938-2016) (2016) (8)
- Heterogeneity across the dorso-ventral axis in zebrafish EVL is regulated by a novel module consisting of sox, snail1a and max genes (2012) (8)
- The great small organisms of developmental genetics: Caenorhabditis elegans and Drosophila melanogaster (2022) (7)
- (Re)Reading The Origin (2009) (6)
- How fish colour their skin: A paradigm for development and evolution of adult patterns (2017) (6)
- Approaches to analyse mood disorders in zebrafish (2008) (5)
- Origin and development of the zebrafish endoderm (1999) (4)
- From Egg to Organism: Studies on Embryonic Pattern Formation (1991) (4)
- Women in science — passion and prejudice (2008) (4)
- (Re)Reading The Origin (2009) (4)
- Walter Gehring (1939–2014) (2014) (3)
- The 1991 Albert Lasker Public Service Award. From egg to organism. Studies on embryonic pattern formation. (1991) (3)
- M-CSFR/CSF1R signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands (2022) (2)
- Fibroblast growth factor signaling in skeletal evolution (2008) (2)
- Of Fish, Fly, Worm, and Man (2000) (2)
- The formation of the embryonic axes in Drosophila (1993) (1)
- Of fish, fly, worm, and man : lessons from developmental biology for human gene function and disease (2000) (0)
- Determination of acron and telson in drosophila requires the torso gene, a putative receptor tyrosine kinase (1989) (0)
- Author response: Gap junctions composed of connexins 41.8 and 39.4 are essential for colour pattern formation in zebrafish (2014) (0)
- Large-Scale Mapping of Mutations Affecting Zebrafish Development Please share how this access benefits you. Your story matters (2007) (0)
- PL-09 Scales and stripes: Genetic analysis of the development of adult structures in the Zebrafish (2009) (0)
- The Hedgehog Signaling Pathway in Vertebrates [ 1 ] (2019) (0)
- Author response: Tight Junction Protein 1a regulates pigment cell organisation during zebrafish colour patterning (2015) (0)
- Fin development is defective in fls and Nkt mutant zebrafish. (2008) (0)
- This convinced me of the powers of a genetic approach . I screened the literature about combining embryology with genetics (2004) (0)
- Active MPF triggers a cascade of events including nuclear envelope breakdown, chromosome condensation, mitotic spindle assembly and cyclin destruction by the anaphase promoting complex (APC). Cyclin destruction in turn results in MPF inactivation, thereby terminating mitosis (2003) (0)
- Hedgehog Signaling Pathway (2019) (0)
- 15-P046 Elucidating the genetic basis of scale loss in fish (2009) (0)
- Hematopoietic mutants identified in a saturation screen of the zebrafish genome (1995) (0)
- Eric Wieschaus (1947- ) [1] (2022) (0)
- Christiane Nusslein-Volhard (1942- ) [1] (2018) (0)
- Redefining Developmental Psychology: Pattern Formation from Genes to Behavior (2008) (0)
- Colony stimulating factor 1 signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands (2021) (0)
- Gain-of-function mutations of mau /DrAqp3a influence zebrafish pigment pattern formation through the tissue environment (2017) (0)
- Home > Hedgehog Signaling Pathway Hedgehog Signaling Pathway (2012) (0)
- Author Correction: Evolution of the potassium channel gene Kcnj13 underlies colour pattern diversification in Danio fish (2021) (0)
- Cis-regulatory evolution of the potassium channel gene kcnj13 during pigment pattern diversification in Danio fish (2022) (0)
- The French Flag Model The French Flag Model (2017) (0)
- Characterisation of role for endothelin signalling in maintenance of quiescence of adult pigment stem cells in zebrafish development (2017) (0)
- 19-P017 Simplet controls cell proliferation and gene transcription during zebrafish caudal fin regeneration (2009) (0)
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