Donald E. Ingber

Q: What Schools Are Affiliated With Donald E. Ingber

Donald E. Ingber is affiliated with the following schools: Jonathan Edwards College, Harvard University, University of Michigan, Medical University of South Carolina, Nagoya University, Massachusetts Institute of Technology, Michigan State University

Donald E. Ingber's AcademicInfluence.com Rankings

Donald E. Ingber

Biology

#837

World Rank

#1453

Historical Rank

#451

USA Rank

Cell Biology

#22

World Rank

#24

Historical Rank

#13

USA Rank

biology Degrees

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Biology

Why Is Donald E. Ingber Influential?

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According to Wikipedia, Donald E. Ingber is an American cell biologist and bioengineer. He is the founding director of the Wyss Institute for Biologically Inspired Engineering at Harvard University, the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children's Hospital, and Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences. He is also a member of the American Institute for Medical and Biological Engineering, the National Academy of Engineering, the National Academy of Medicine, the National Academy of Inventors, and the American Academy of Arts and Sciences.

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Donald E. Ingber's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Geometric control of cell life and death. (1997) (4505)
Reconstituting Organ-Level Lung Functions on a Chip (2010) (2890)
Soft lithography in biology and biochemistry. (2001) (2351)
Microfluidic organs-on-chips (2014) (2186)
Mechanotransduction across the cell surface and through the cytoskeleton (1993) (2113)
Induction of angiogenesis during the transition from hyperplasia to neoplasia (1989) (1959)
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells (2003) (1931)
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. (1997) (1657)
Tensegrity: the architectural basis of cellular mechanotransduction. (1997) (1605)
Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus (2009) (1544)
Cellular mechanotransduction: putting all the pieces together again (2006) (1506)
From 3D cell culture to organs-on-chips. (2011) (1464)
Patterning proteins and cells using soft lithography. (1999) (1463)
Engineering cell shape and function. (1994) (1340)
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth (1990) (1259)
Tensegrity I. Cell structure and hierarchical systems biology (2003) (1252)
Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. (2012) (1169)
Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. (1993) (1150)
Transcriptome-wide noise controls lineage choice in mammalian progenitor cells (2008) (1059)
Mechanotransduction across the cell surface and through the cytoskeleton. (1993) (1052)
A heparin-binding angiogenic protein--basic fibroblast growth factor--is stored within basement membrane. (1988) (941)
Tensegrity II. How structural networks influence cellular information processing networks (2003) (830)
Mechanochemical switching between growth and differentiation during fibroblast growth factor-stimulated angiogenesis in vitro: role of extracellular matrix (1989) (779)
The structural and mechanical complexity of cell-growth control (1999) (767)
Mechanobiology and diseases of mechanotransduction (2003) (765)
Mechanical control of tissue and organ development (2010) (762)
A Human Disease Model of Drug Toxicity–Induced Pulmonary Edema in a Lung-on-a-Chip Microdevice (2012) (743)
Mechanical behavior in living cells consistent with the tensegrity model (2001) (722)
Integrins as mechanochemical transducers. (1991) (704)
Micropatterned Surfaces for Control of Cell Shape, Position, and Function (1998) (696)
Vacuum-assisted closure: microdeformations of wounds and cell proliferation. (2004) (663)
Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. (2006) (660)
Cell fates as high-dimensional attractor states of a complex gene regulatory network. (2005) (650)
Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip (2015) (625)
Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement (2006) (621)
Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology. (2002) (615)
Human kidney proximal tubule-on-a-chip for drug transport and nephrotoxicity assessment. (2013) (612)
Shape-dependent control of cell growth, differentiation, and apoptosis: switching between attractors in cell regulatory networks. (2000) (610)
The architecture of life. (1998) (596)
Tissue engineering by cell transplantation using degradable polymer substrates. (1991) (582)
Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation. (1993) (577)
Microengineered physiological biomimicry: organs-on-chips. (2012) (576)
Cell shape provides global control of focal adhesion assembly. (2003) (563)
Control of cytoskeletal mechanics by extracellular matrix, cell shape, and mechanical tension. (1994) (557)
Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex. (1995) (547)
Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. (2013) (530)
Cellular control lies in the balance of forces. (1998) (526)
Small airway-on-a-chip enables analysis of human lung inflammation and drug responses in vitro (2015) (523)
Control of cyclin D1, p27(Kip1), and cell cycle progression in human capillary endothelial cells by cell shape and cytoskeletal tension. (1998) (516)
Microfabrication of human organs-on-chips (2013) (515)
Mechanotransduction: All Signals Point to Cytoskeleton, Matrix, and Integrins (2002) (515)
A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling (2014) (507)
A mechanosensitive transcriptional mechanism that controls angiogenesis (2009) (505)
Fibronectin controls capillary endothelial cell growth by modulating cell shape. (1990) (504)
Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. (2000) (501)
How does extracellular matrix control capillary morphogenesis? (1989) (479)
Impaired mechanical stability, migration and contractile capacity in vimentin-deficient fibroblasts. (1998) (471)
Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells. (1994) (465)
Directional control of lamellipodia extension by constraining cell shape and orienting cell tractional forces (2002) (458)
Switching from differentiation to growth in hepatocytes: Control by extracellular matrix (1992) (454)
Cellular adaptation to mechanical stress: role of integrins, Rho, cytoskeletal tension and mechanosensitive ion channels (2006) (449)
Geometric control of switching between growth, apoptosis, and differentiation during angiogenesis using micropatterned substrates (1999) (446)
Cellular tensegrity: exploring how mechanical changes in the cytoskeleton regulate cell growth, migration, and tissue pattern during morphogenesis. (1994) (444)
High-Betweenness Proteins in the Yeast Protein Interaction Network (2005) (442)
Modelling cancer in microfluidic human organs-on-chips (2019) (441)
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids (2018) (434)
Using microcontact printing to pattern the attachment of mammalian cells to self-assembled monolayers of alkanethiolates on transparent films of gold and silver. (1997) (434)
Laminar flows: Subcellular positioning of small molecules (2001) (425)
Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels (2012) (423)
Engineered in vitro disease models. (2015) (422)
Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1 (2008) (417)
Cell tension, matrix mechanics, and cancer development. (2005) (413)
Tensegrity-based mechanosensing from macro to micro. (2008) (399)
Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions (1998) (391)
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip (2019) (381)
Combined microfluidic-micromagnetic separation of living cells in continuous flow (2006) (381)
Mechanosensitive mechanisms in transcriptional regulation (2012) (376)
Paper-supported 3D cell culture for tissue-based bioassays (2009) (371)
Microfluidic Organ-on-a-Chip Models of Human Intestine (2018) (361)
Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown (1993) (361)
Controlling cell attachment on contoured surfaces with self-assembled monolayers of alkanethiolates on gold. (1996) (356)
Mechanobiology and developmental control. (2013) (353)
Tensegrity, cellular biophysics, and the mechanics of living systems (2014) (351)
Mechanical control of tissue morphogenesis during embryological development. (2006) (351)
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets (2021) (347)
Prevascularization of porous biodegradable polymers (1993) (345)
Bone marrow–on–a–chip replicates hematopoietic niche physiology in vitro (2014) (344)
Cell shape, cytoskeletal mechanics, and cell cycle control in angiogenesis. (1995) (343)
Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. (1991) (342)
Matrix Elasticity of Void-Forming Hydrogels Controls Transplanted Stem Cell-Mediated Bone Formation (2015) (336)
Quantifying cell-generated mechanical forces within living embryonic tissues (2013) (335)
Distinct Contributions of Astrocytes and Pericytes to Neuroinflammation Identified in a 3D Human Blood-Brain Barrier on a Chip (2016) (321)
Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip (2017) (316)
Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent. (1991) (315)
TRPV4 Channels Mediate Cyclic Strain–Induced Endothelial Cell Reorientation Through Integrin-to-Integrin Signaling (2009) (306)
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies (2019) (299)
Micropatterning tractional forces in living cells. (2002) (297)
Tissue engineering and developmental biology: going biomimetic. (2006) (289)
Can cancer be reversed by engineering the tumor microenvironment? (2008) (280)
Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape. (1992) (278)
Using Mixed Self-Assembled Monolayers Presenting RGD and (EG)3OH Groups To Characterize Long-Term Attachment of Bovine Capillary Endothelial Cells to Surfaces (1998) (276)
Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton. (1997) (274)
Nanomagnetic actuation of receptor-mediated signal transduction. (2008) (272)
Angiostatic steroids. Method of discovery and mechanism of action. (1987) (268)
A combined micromagnetic-microfluidic device for rapid capture and culture of rare circulating tumor cells. (2012) (260)
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. (2017) (259)
How cells (might) sense microgravity (1999) (257)
Control of basement membrane remodeling and epithelial branching morphogenesis in embryonic lung by Rho and cytoskeletal tension (2005) (257)
Extracellular matrix and cell shape: Potential control points for inhibition of angiogenesis (1991) (255)
Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. (2003) (255)
Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice. (2012) (253)
Mechanical control of cyclic AMP signalling and gene transcription through integrins (2000) (252)
Probing transmembrane mechanical coupling and cytomechanics using magnetic twisting cytometry. (1995) (249)
Inhibition of angiogenesis through modulation of collagen metabolism. (1988) (247)
Geometric determinants of directional cell motility revealed using microcontact printing. (2003) (246)
A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells (2018) (243)
Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470). (1994) (242)
Self-assembly of 3D prestressed tensegrity structures from DNA (2010) (241)
Mechanical forces alter zyxin unbinding kinetics within focal adhesions of living cells (2006) (240)
Control of intracellular pH and growth by fibronectin in capillary endothelial cells (1990) (240)
An extracorporeal blood-cleansing device for sepsis therapy (2014) (238)
Tumor-Derived Extracellular Vesicles Breach the Intact Blood Brain Barrier via Transcytosis. (2019) (233)
Role of RhoA, mDia, and ROCK in Cell Shape-dependent Control of the Skp2-p27kip1 Pathway and the G1/S Transition* (2004) (231)
Leukocyte adhesion to vascular endothelium induces E-selectin linkage to the actin cytoskeleton (1996) (231)
The riddle of morphogenesis: A question of solution chemistry or molecular cell engineering? (1993) (230)
Inhibition of angiogenesis. (1992) (228)
Ultra-rapid activation of TRPV4 ion channels by mechanical forces applied to cell surface beta1 integrins. (2010) (227)
Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix. (1995) (225)
Reproducing human and cross-species drug toxicities using a Liver-Chip (2019) (225)
Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells? (1998) (221)
Selective chemical treatment of cellular microdomains using multiple laminar streams. (2003) (219)
Selective Deposition of Proteins and Cells in Arrays of Microwells (2001) (219)
Analysis of cell mechanics in single vinculin-deficient cells using a magnetic tweezer. (2000) (219)
Mechanical control of tissue growth: function follows form. (2005) (211)
A possible mechanism for inhibition of angiogenesis by angiostatic steroids: induction of capillary basement membrane dissolution. (1986) (210)
Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function. (2017) (206)
Extracellular matrix controls myosin light chain phosphorylation and cell contractility through modulation of cell shape and cytoskeletal prestress. (2004) (205)
Primary Human Lung Alveolus‐on‐a‐chip Model of Intravascular Thrombosis for Assessment of Therapeutics (2018) (204)
Nanoparticle targeting of anti-cancer drugs that alter intracellular signaling or influence the tumor microenvironment. (2014) (202)
Role of basal lamina in neoplastic disorganization of tissue architecture. (1981) (202)
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips (2020) (202)
Cytoskeletal control of growth and cell fate switching. (2009) (202)
Micromechanical control of cell and tissue development: implications for tissue engineering. (2007) (201)
Controlling Mammalian Cell Spreading and Cytoskeletal Arrangement with Conveniently Fabricated Continuous Wavy Features on Poly(dimethylsiloxane) (2002) (200)
Integrin binding and cell spreading on extracellular matrix act at different points in the cell cycle to promote hepatocyte growth. (1994) (198)
Multizone Paper Platform for 3D Cell Cultures (2011) (196)
Integrating with integrins. (1994) (196)
Mechanosensation through integrins: Cells act locally but think globally (2003) (196)
Mechanotransduction of fluid stresses governs 3D cell migration (2014) (194)
Micromagnetic-microfluidic blood cleansing device. (2009) (193)
Robotic fluidic coupling and interrogation of multiple vascularized organ chips (2020) (193)
The Shedding of Membrane-anchored Heparin-binding Epidermal-like Growth Factor Is Regulated by the Raf/Mitogen-activated Protein Kinase Cascade and by Cell Adhesion and Spreading* (1999) (192)
Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering (2007) (189)
Biomechanics: Cell Research and Applications for the Next Decade (2009) (189)
Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro (2008) (188)
Gene Expression Dynamics Inspector (GEDI): for integrative analysis of expression profiles (2003) (187)
Matched-Comparative Modeling of Normal and Diseased Human Airway Responses Using a Microengineered Breathing Lung Chip. (2016) (186)
Tensegrity and mechanotransduction. (2008) (186)
Cytoskeletal mechanics in pressure-overload cardiac hypertrophy. (1997) (181)
Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation. (2011) (180)
Pulse energy dependence of subcellular dissection by femtosecond laser pulses. (2005) (180)
Evidence by molecular profiling for a placental origin of infantile hemangioma. (2005) (178)
Forty-Year Journey of Angiogenesis Translational Research (2011) (178)
Angiopoietin-1 Requires p190 RhoGAP to Protect against Vascular Leakage in Vivo* (2007) (178)
Opposing views on tensegrity as a structural framework for understanding cell mechanics. (2000) (177)
Rapid induction and isolation of focal adhesion complexes. (1993) (177)
Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction. (2006) (176)
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. (2007) (172)
Multiple integrins share the ability to induce elevation of intracellular pH. (1991) (172)
Cancer as a disease of epithelial-mesenchymal interactions and extracellular matrix regulation. (2002) (169)
Models of cytoskeletal mechanics of adherent cells (2002) (167)
A microstructural approach to cytoskeletal mechanics based on tensegrity. (1996) (163)
An antifouling coating that enables affinity-based electrochemical biosensing in complex biological fluids (2019) (162)
Directional control of cell motility through focal adhesion positioning and spatial control of Rac activation (2008) (161)
Multistable and multistep dynamics in neutrophil differentiation (2006) (161)
Reverse Engineering Human Pathophysiology with Organs-on-Chips (2016) (158)
Stability of Surface-Immobilized Lubricant Interfaces under Flow (2015) (156)
A human breathing lung‐on‐a‐chip (2010) (156)
A non-genetic basis for cancer progression and metastasis: self-organizing attractors in cell regulatory networks. (2006) (155)
Mechanical continuity and reversible chromosome disassembly within intact genomes removed from living cells (1997) (154)
Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion (2010) (151)
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV‐1 envelope (2002) (148)
Mechanical properties of individual focal adhesions probed with a magnetic microneedle. (2004) (145)
Ablation of cytoskeletal filaments and mitochondria in live cells using a femtosecond laser nanoscissor. (2005) (144)
Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities. (2017) (143)
Human organs-on-chips for disease modelling, drug development and personalized medicine (2022) (143)
On-chip recapitulation of clinical bone-marrow toxicities and patient-specific pathophysiology (2019) (141)
Hepatocyte culture on biodegradable polymeric substrates (1991) (138)
Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape. (2018) (137)
Tensile Forces Stimulate Vascular Remodeling and Epidermal Cell Proliferation in Living Skin (2007) (136)
Inhibition of endothelial cell migration by thrombospondin-1 type-1 repeats is mediated by β1 integrins (2005) (135)
1 – Tension and Compression as Basic Determinants of Cell Form and Function: Utilization of a Cellular Tensegrity Mechanism (1989) (133)
A combinatorial cell-laden gel microarray for inducing osteogenic differentiation of human mesenchymal stem cells (2014) (132)
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics (2021) (130)
A Computational Tensegrity Model Predicts Dynamic Rheological Behaviors in Living Cells (2004) (130)
α-Actinin-4 Is Required for Normal Podocyte Adhesion* (2007) (129)
Human Gut-On-A-Chip Supports Polarized Infection of Coxsackie B1 Virus In Vitro (2017) (129)
A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function (2016) (128)
Topographical Micropatterning of Poly(dimethylsiloxane) Using Laminar Flows of Liquids in Capillaries (2001) (126)
Epoxyeicosanoids promote organ and tissue regeneration (2013) (126)
Global cytoskeletal control of mechanotransduction in kidney epithelial cells. (2004) (119)
Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems. (2015) (119)
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip (2018) (119)
Tensegrity and mechanoregulation: from skeleton to cytoskeleton. (1999) (116)
Basement membrane as a spatial organizer of polarized epithelia. Exogenous basement membrane reorients pancreatic epithelial tumor cells in vitro. (1986) (114)
Physiologically Based Pharmacokinetic and Pharmacodynamic Analysis Enabled by Microfluidically Linked Organs-on-Chips. (2018) (113)
Extracellular matrix as a solid-state regulator in angiogenesis: identification of new targets for anti-cancer therapy. (1992) (113)
Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy (2015) (112)
Is it Time for Reviewer 3 to Request Human Organ Chip Experiments Instead of Animal Validation Studies? (2020) (112)
Self-assembly of three-dimensional prestressed tensegrity structures from DNA (2010) (112)
Integrins, tensegrity, and mechanotransduction. (1997) (108)
A Wnt-Bmp Feedback Circuit Controls Intertissue Signaling Dynamics in Tooth Organogenesis (2012) (107)
Platform for high-throughput testing of the effect of soluble compounds on 3D cell cultures. (2013) (107)
Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and Physiology (2019) (106)
Intact vinculin protein is required for control of cell shape, cell mechanics, and rac-dependent lamellipodia formation. (2002) (106)
The mechanochemical basis of cell and tissue regulation. (2004) (105)
Binding of urokinase to plasminogen activator inhibitor type-1 mediates cell adhesion and spreading. (1997) (105)
Clear castable polyurethane elastomer for fabrication of microfluidic devices. (2013) (105)
Rheological behavior of living cells is timescale-dependent. (2007) (105)
Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells (2010) (105)
Biology-Inspired Microphysiological Systems to Advance Patient Benefit and Animal Welfare in Drug Development (2020) (104)
Noise-Driven Stem Cell and Progenitor Population Dynamics (2008) (104)
Control of lung vascular permeability and endotoxin-induced pulmonary oedema by changes in extracellular matrix mechanics (2013) (103)
Filamin links cell shape and cytoskeletal structure to Rho regulation by controlling accumulation of p190RhoGAP in lipid rafts (2007) (103)
Cooperative control of Akt phosphorylation, bcl-2 expression, and apoptosis by cytoskeletal microfilaments and microtubules in capillary endothelial cells. (2001) (102)
Symmetry-breaking in mammalian cell cohort migration during tissue pattern formation: role of random-walk persistence. (2005) (102)
Adhesion-dependent control of matrix metalloproteinase-2 activation in human capillary endothelial cells. (2000) (102)
Nogo-A is a negative regulator of CNS angiogenesis (2013) (101)
α4β1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the α4-cytoplasmic domain (2005) (100)
Manufacturing of Large-Scale Functional Objects Using Biodegradable Chitosan Bioplastic (2014) (100)
Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip (2018) (99)
ABL2/ARG Tyrosine Kinase Mediates SEMA3F-induced RhoA Inactivation and Cytoskeleton Collapse in Human Glioma Cells* (2008) (99)
A multi-modular tensegrity model of an actin stress fiber. (2008) (98)
From Cellular Mechanotransduction to Biologically Inspired Engineering (2010) (98)
Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium (2016) (96)
Unexpected Strength and Toughness in Chitosan‐Fibroin Laminates Inspired by Insect Cuticle (2012) (96)
Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. (2012) (93)
Estrogen-receptor-α exchange and chromatin dynamics are ligand- and domain-dependent (2006) (93)
Human Intestinal Morphogenesis Controlled by Transepithelial Morphogen Gradient and Flow-Dependent Physical Cues in a Microengineered Gut-on-a-Chip (2019) (92)
Cellular basis of mechanotransduction. (1998) (90)
Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation. (1998) (87)
Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites (2019) (87)
A discrete cell cycle checkpoint in late G(1) that is cytoskeleton-dependent and MAP kinase (Erk)-independent. (2002) (87)
Morpho: A self-deformable modular robot inspired by cellular structure (2008) (83)
What lies at the interface of regenerative medicine and developmental biology? (2007) (83)
Magnetically-guided self-assembly of fibrin matrices with ordered nano-scale structure for tissue engineering. (2006) (81)
Carbon metabolism-mediated myogenic differentiation (2009) (79)
Developmentally inspired human ‘organs on chips’ (2018) (77)
Absence of Cyclooxygenase-2 Exacerbates Hypoxia-Induced Pulmonary Hypertension and Enhances Contractility of Vascular Smooth Muscle Cells (2008) (77)
Organ‐on‐Chip Recapitulates Thrombosis Induced by an anti‐CD154 Monoclonal Antibody: Translational Potential of Advanced Microengineered Systems (2018) (74)
The origin of cellular life. (2000) (73)
Tensegrity-guided self assembly: from molecules to living cells (2009) (72)
Biomechanical forces promote blood development through prostaglandin E2 and the cAMP–PKA signaling axis (2015) (70)
Integrin-dependent induction of early growth response genes in capillary endothelial cells. (1996) (70)
Non-invasive sensing of transepithelial barrier function and tissue differentiation in organs-on-chips using impedance spectroscopy. (2019) (68)
Silencing HoxA1 by Intraductal Injection of siRNA Lipidoid Nanoparticles Prevents Mammary Tumor Progression in Mice (2014) (67)
Human organs-on-chips as tools for repurposing approved drugs as potential influenza and COVID19 therapeutics in viral pandemics (2020) (65)
Human Organs-on-Chips for Virology (2020) (64)
Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin a5,fi, independent of cell shape (64)
Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis (2014) (63)
Investigating complexity of protein-protein interactions in focal adhesions. (2008) (62)
Electromagnetic needles with submicron pole tip radii for nanomanipulation of biomolecules and living cells (2004) (61)
Rho signaling and mechanical control of vascular development (2008) (61)
A mini-microscope for in situ monitoring of cells. (2012) (61)
Novel dynamic rheological behavior of individual focal adhesions measured within single cells using electromagnetic pulling cytometry. (2005) (60)
Improved treatment of systemic blood infections using antibiotics with extracorporeal opsonin hemoadsorption. (2015) (60)
Control of embryonic lung branching morphogenesis by the Rho activator, cytotoxic necrotizing factor 1. (2002) (59)
Tools to study cell mechanics and mechanotransduction. (2007) (59)
Collective construction of environmentally-adaptive structures (2007) (58)
Bioinspired Chitinous Material Solutions for Environmental Sustainability and Medicine (2013) (58)
Caldesmon-dependent switching between capillary endothelial cell growth and apoptosis through modulation of cell shape and contractility (2004) (58)
Fibronectin Unfolding Revisited: Modeling Cell Traction-Mediated Unfolding of the Tenth Type-III Repeat (2008) (57)
Control of cancer formation by intrinsic genetic noise and microenvironmental cues (2015) (57)
Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. (1998) (57)
Synaptic Reorganization in Scaled Networks of Controlled Size (2007) (56)
Towards a Holistic, Yet Gene-Centered Analysis of Gene Expression Profiles: A Case Study of Human Lung Cancers (2006) (56)
Direct binding of F actin to the cytoplasmic domain of the alpha 2 integrin chain in vitro. (1995) (55)
A microdevice for rapid optical detection of magnetically captured rare blood pathogens. (2014) (55)
SEBS elastomers for fabrication of microfluidic devices with reduced drug absorption by injection molding and extrusion (2017) (55)
Extracellular matrix controls tubulin monomer levels in hepatocytes by regulating protein turnover. (1994) (53)
Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device. (2016) (53)
Force meets chemistry: Analysis of mechanochemical conversion in focal adhesions using fluorescence recovery after photobleaching (2006) (53)
Mechanical control of cAMP signaling through integrins is mediated by the heterotrimeric Gαs protein (2009) (52)
Discovery of potent and practical antiangiogenic agents inspired by cortistatin A. (2009) (52)
Control of capillary growth and differentiation by extracellular matrix. Use of a tensegrity (tensional integrity) mechanism for signal processing. (1991) (52)
Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery. (2017) (50)
Cell surface properties of normal, differentiating, and neoplastic pancreatic acinar cells (1981) (49)
Human Lung Small Airway-on-a-Chip Protocol. (2017) (49)
YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow. (2020) (48)
Inhibition of tumor-cell attachment to extracellular matrix as a method for preventing tumor recurrence in a surgical wound. (1989) (48)
CHAPTER 2 – Mechanochemical Transduction across Extracellular Matrix and through the Cytoskeleton (1993) (47)
Paxillin Mediates Sensing of Physical Cues and Regulates Directional Cell Motility by Controlling Lamellipodia Positioning (2011) (46)
PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury (2018) (46)
Endothelial growth factors and extracellular matrix regulate DNA synthesis through modulation of cell and nuclear expansion (1987) (46)
Hollow Fibers for Hepatocyte Encapsulation and Transplantation: Studies of Survival and Function in Rats (1994) (46)
Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. (2006) (46)
Modeling Hematopoiesis and Responses to Radiation Countermeasures in a Bone Marrow-on-a-Chip. (2016) (45)
Principles of Tissue Engineering and Reconstruction Using Polymer-Cell Constructs (1991) (45)
Cellular nanoscale stiffness patterns governed by intracellular forces (2019) (44)
Biology-inspired microphysiological systems to advance medicines for patient benefit and animal welfare. (2020) (43)
Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models (2019) (42)
Integrin-dependent control of inositol lipid synthesis in vascular endothelial cells and smooth muscle cells. (1996) (41)
Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients (2020) (41)
Nanostructured magnetizable materials that switch cells between life and death. (2007) (40)
In search of cellular control: Signal transduction in context (1998) (40)
Using self-assembled monolayers to pattern ECM proteins and cells on substrates. (2009) (39)
Paxillin controls endothelial cell migration and tumor angiogenesis by altering neuropilin 2 expression (2014) (39)
Targeted drug delivery to flow-obstructed blood vessels using mechanically activated nanotherapeutics. (2015) (39)
Molecular Signaling (2002) (39)
Organs on Chips 2013. (2013) (39)
Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. (2012) (39)
Neoplastic disorganization of pancreatic epithelial cell-cell relations. Role of basement membrane. (1985) (38)
Integrins β1, α6, and α3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms (2006) (37)
Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles. (2015) (37)
DNA topoisomerase II can drive changes in higher order chromosome architecture without enzymatically modifying DNA (1998) (37)
How Changes in Extracellular Matrix Mechanics and Gene Expression Variability Might Combine to Drive Cancer Progression (2013) (37)
A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood (2016) (36)
Shear-Activated Nanoparticle Aggregates Combined With Temporary Endovascular Bypass to Treat Large Vessel Occlusion (2015) (35)
A mathematical model to determine molecular kinetic rate constants under non-steady state conditions using fluorescence recovery after photobleaching (FRAP). (2006) (35)
Heparin-binding angiogenesis factors: detection by immunological methods. (1987) (35)
A Biologically Inspired, Functionally Graded End Effector for Soft Robotics Applications. (2017) (34)
Methods for measuring rates of protein binding to insoluble scaffolds in living cells: Histone H1‐chromatin interactions (2006) (33)
Breast cancer normalization induced by embryonic mesenchyme is mediated by extracellular matrix biglycan. (2013) (33)
Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics (2020) (32)
Graphene Enabled Low‐Noise Surface Chemistry for Multiplexed Sepsis Biomarker Detection in Whole Blood (2021) (32)
An improved mathematical approach for determination of molecular kinetics in living cells with FRAP. (2004) (32)
From Three-Dimensional Cell Culture to Organs-on-Chips (2015) (32)
Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. (1998) (31)
Programed Death is Favored by Natural Selection in Spatial Systems. (2015) (31)
LRP5 Regulates Development of Lung Microvessels and Alveoli through the Angiopoietin-Tie2 Pathway (2012) (31)
A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma (2022) (31)
CHAPTER 9 – MECHANICAL AND CHEMICAL DETERMINANTS OF TISSUE DEVELOPMENT (2000) (31)
Use of micropatterned adhesive surfaces for control of cell behavior. (2002) (31)
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2 (2021) (30)
Scalable Fabrication of Stretchable, Dual Channel, Microfluidic Organ Chips. (2018) (30)
Treatment of psoriasis with NFKBIZ siRNA using topical ionic liquid formulations (2020) (29)
Self-organization of environmentally-adaptive shapes on a modular robot (2007) (29)
An artificial vasculature for adaptive thermal control of windows (2013) (29)
Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size. (2000) (28)
Developing microphysiological systems for use as regulatory tools--challenges and opportunities. (2014) (27)
Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland (2013) (27)
Induction of Hepatocyte Differentiation by the Extracellular Matrix and an RGD-Containing Synthetic Peptide (1991) (27)
From mechanobiology to developmentally inspired engineering (2018) (27)
New role for tRNA and its fragment purified from human urinary bladder carcinoma conditioned medium: Inhibition of endothelial cell growth (1999) (26)
Rapid Isolation of Staphylococcus aureus Pathogens from Infected Clinical Samples Using Magnetic Beads Coated with Fc-Mannose Binding Lectin (2016) (25)
Low Urine Vascular Endothelial Growth Factor Levels Are Associated with Mechanical Ventilation, Bronchopulmonary Dysplasia and Retinopathy of Prematurity (2013) (24)
Acceleration of Lung Regeneration by Platelet-Rich Plasma Extract through the Low-Density Lipoprotein Receptor-Related Protein 5-Tie2 Pathway. (2016) (24)
Mechanical Signaling (2002) (24)
Regulation of cytoskeletal mechanics and cell growth by myosin light chain phosphorylation. (1998) (24)
Mechanical control of innate immune responses against viral infection revealed in a human lung alveolus chip (2021) (24)
l-Caldesmon Regulates Proliferation and Migration of Vascular Smooth Muscle Cells and Inhibits Neointimal Formation After Angioplasty (2006) (24)
Developmentally‐Inspired Shrink‐Wrap Polymers for Mechanical Induction of Tissue Differentiation (2014) (24)
SLLISWD Sequence in the 10FNIII Domain Initiates Fibronectin Fibrillogenesis* (2013) (22)
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy In Vitro. (2018) (22)
Tumor formation and malignant invasion: role of basal lamina (1982) (21)
Modeling pulmonary cystic fibrosis in a human lung airway-on-a-chip: Cystic fibrosis airway chip. (2021) (21)
Human Gut-OnA-Chip Supports Polarized Infection of Coxsackie B 1 Virus In Vitro (2017) (21)
Tissue adaptation to mechanical forces in healthy, injured and aging tissues (2005) (21)
Paxillin controls directional cell motility in response to physical cues (2012) (21)
Discovery of influenza drug resistance mutations and host therapeutic targets using a human airway chip (2019) (21)
Simulating drug concentrations in PDMS microfluidic organ chips. (2021) (21)
Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection (2020) (20)
An IC/microfluidic hybrid microsystem for 2D magnetic manipulation of individual biological cells (2005) (20)
Modulation of adhesion-dependent cAMP signaling by echistatin and alendronate. (1996) (20)
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip (2021) (20)
Symmetry breaking in cultured mammalian cells (2001) (19)
Broad-spectrum capture of clinical pathogens using engineered Fc-mannose-binding lectin enhanced by antibiotic treatment (2019) (19)
AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage (2019) (19)
Erratum: Estrogen-receptor-α exchange and chromatin dynamics are ligand- and domain-independent (J. Cell Sci. vol. 119 (4101-4116)) (2006) (18)
4 – Regulation of Nucleocytoplasmic Transport by Mechanical Forces Transmitted Through the Cytoskeleton (1992) (18)
Biomimetic smoking robot for in vitro inhalation exposure compatible with microfluidic organ chips (2020) (18)
Activation of Mechanosensitive Ion Channels by Forces Transmitted Through Integrins and the Cytoskeleton (2007) (17)
Control of the direction of lamellipodia extension through changes in the balance between Rac and Rho activities. (2005) (17)
Mononuclear Cells from Dedifferentiation of Mouse Myotubes Display Remarkable Regenerative Capability (2014) (17)
Mechanical induction of dentin-like differentiation by adult mouse bone marrow stromal cells using compressive scaffolds. (2017) (17)
Transplantation of genetically altered hepatocytes using cell-polymer constructs. (1993) (16)
Controllable Fabrication of Inhomogeneous Microcapsules for Triggered Release by Osmotic Pressure. (2019) (16)
Generation of biocompatible droplets for in vivo and in vitro measurement of cell-generated mechanical stresses. (2015) (16)
Corrigendum to “Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton” [Exp. Cell Res. 231 (1997) 14–26] (2008) (16)
Complex human gut microbiome cultured in anaerobic human intestine chips (2018) (16)
Integrins beta1, alpha6, and alpha3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms. (2006) (15)
Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock (2021) (15)
Dongeun Huh Lung-ona-Chip Microdevice Induced Pulmonary Edema in a − A Human Disease Model of Drug Toxicity (2012) (15)
Application of a Halbach magnetic array for long-range cell and particle separations in biological samples (2016) (14)
Mesenchymal condensation‐dependent accumulation of collagen VI stabilizes organ‐specific cell fates during embryonic tooth formation (2015) (14)
Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis (2019) (14)
Ionic control of chromosome architecture in living and permeabilized cells. (1998) (14)
Lab on a chip: United States of America. (2012) (14)
Regulation of endothelial growth factor action: solid state control by extracellular matrix. (1987) (14)
Multi-scale modeling reveals use of hierarchical tensegrity principles at the molecular, multi-molecular, and cellular levels (2018) (13)
Qualifying a human Liver-Chip for predictive toxicology: Performance assessment and economic implications (2021) (13)
Chip Reconstituting Organ-Level Lung Functions on a (2010) (13)
Origami microfluidics for radiant cooling with small temperature differences in buildings (2020) (13)
Enabling Multiplexed Electrochemical Detection of Biomarkers with High Sensitivity in Complex Biological Samples. (2021) (13)
Symmetry breaking in cultured mammalian cells (2000) (13)
Enhancement of experimental lung metastases by cultured B16 melanoma cells treated with (+/-)-1,2-bis(3,5-dioxopiperazin-1-y)propane (ICRF-159). (1978) (13)
Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology (2022) (12)
Phosphorylation of ACTN4 Leads to Podocyte Vulnerability and Proteinuric Glomerulosclerosis. (2020) (12)
Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (2022) (12)
Using self-assembled monolayers to pattern ECM proteins and cells on substrates. (2000) (12)
Direct Bonding of Chitosan Biomaterials to Tissues Using Transglutaminase for Surgical Repair or Device Implantation. (2017) (12)
Theory and associated phenomenology for intrinsic mortality arising from natural selection (2015) (12)
Clinically Relevant Influenza Virus Evolution Reconstituted in a Human Lung Airway-on-a-Chip (2021) (12)
EXTRACELLULAR MATRIX, CELLULAR MECHANICS AND TISSUE ENGINEERING (1993) (11)
Cover Picture: Shear‐Responsive Platelet Mimetics for Targeted Drug Delivery (Isr. J. Chem. 9‐10/2013) (2013) (11)
AEROSOL DRUG DELIVERY FOR LUNG ON A CHIP (2011) (11)
Is cytoskeletal tension a major determinant of cell deformability in adherent endothelial cells? (1998) (11)
Metabolism of tumor regression from angiogenesis inhibition: 31P magnetic resonance spectroscopy (1989) (11)
Cellular Tensegrity and Mechanochemical Transduction (1994) (11)
Rapid Coating Process Generates Omniphobic Dentures in Minutes to Reduce C. albicans Biofouling. (2018) (10)
The Wyss institute: A new model for medical technology innovation and translation across the academic‐industrial interface (2017) (10)
Soft Lithography and Microfluidics (2002) (10)
A robotic platform for fluidically-linked human body-on-chips experimentation (2019) (10)
Patterning the topographical environment for mammalian cell culture using laminar flows in capillaries (2000) (9)
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function, drug penetration, and antibody shuttling properties (2018) (9)
An Engineered Human Fc‐Mannose‐Binding‐Lectin Captures Circulating Tumor Cells (2017) (9)
Ultrarapid Method for Coating Electrochemical Sensors with Antifouling Conductive Nanomaterials Enables Highly Sensitive Multiplexed Detection in Whole Blood (2021) (9)
CELLULAR TENSEGRITY MODELS AND CELL-SUBSTRATE INTERACTIONS (2006) (9)
Vaginal microbiome-host interactions modeled in a human vagina-on-a-chip (2022) (9)
Liver-Chip: Reproducing Human and Cross-Species Toxicities (2019) (9)
Squaring up to the cell-shape debate (1999) (9)
From Molecular Cell Engineering to Biologically Inspired Engineering (2008) (9)
Modified Clinical Monitoring Assessment Criteria for Multi-Organ Failure during Bacteremia and Sepsis Progression in a Pig Model (2018) (9)
Modeling Pulmonary Cystic Fibrosis in a Human Lung Airway-on-a-chip (2021) (9)
Human bone marrow disorders recapitulated in vitro using organ chip technology (2018) (9)
Anomalous COVID-19 tests hinder researchers (2021) (8)
Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism (2020) (8)
A universal set of building rules seems to guide the design of organic structures—from simple carbon compounds to complex cells and tissues (1998) (8)
Shear-Responsive Platelet Mimetics for Targeted Drug Delivery (2013) (8)
Commendation for Exposing Key Advantage of Organ Chip Approach. (2016) (8)
Biological design principles that guide self-organization, emergence, and hierarchical assembly: from complexity to tensegrity (2000) (8)
Corrigendum: Quantifying cell-generated mechanical forces within living embryonic tissues (2014) (8)
Tensegrity, Dynamic Networks, and Complex Systems Biology: Emergence in Structural and Information Networks Within Living Cells (2006) (8)
Methods for studying mechanical control of angiogenesis by the cytoskeleton and extracellular matrix. (2008) (8)
Proteomic and Metabolomic Characterization of Human Neurovascular Unit Cells in Response to Methamphetamine. (2020) (8)
Laboratory-Generated DNA Can Cause Anomalous Pathogen Diagnostic Test Results (2021) (8)
From Stem Cells to Functional Tissue Architecture (2004) (8)
Identification of a distinct class of cytoskeleton-associated mRNAs using microarray technology (2003) (7)
Lymph node follicle formation and vaccination responses reconstituted in vitro in a human Organ Chip (2019) (7)
The Mechanical and Cytoskeletal Basis of Lung Morphogenesis (2004) (7)
Hepatocyte transplantation into prevascularized porous matrices (1992) (7)
The Architecture of Life A universal set of building rules seems to guide the design of organic structures — from simple carbon compounds to complex cells and tissues (1999) (7)
Rapid Prototyping of Thermoplastic Microfluidic Devices. (2018) (7)
Art Advancing Science: Filmmaking Leads to Molecular Insights at the Nanoscale. (2017) (7)
Transferrin receptor targeting by de novo sheet extension (2021) (7)
Magnetic cellular switches (2004) (6)
New anticoagulant coatings and hemostasis assessment tools to avoid complications with pediatric left ventricular assist devices (2017) (6)
Collective Shape Actuation of Polymer Double Emulsions by Solvent Evaporation. (2018) (6)
Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction (2022) (6)
Tensegrity architecture and the mammalian cell cytoskeleton (2007) (6)
The Wyss Institute at Harvard University (2011) (6)
Establishment of physiologically relevant oxygen gradients in microfluidic organ chips. (2022) (6)
What can an organ-on-a-chip teach us about human lung physiology? (2022) (6)
Evidence generation and reproducibility in cell and gene therapy research: A call to action (2021) (6)
HUMAN KIDNEY PROXIMAL TUBULE-ON-A-CHIP FOR DRUG TRANS- PORTER STUDIES AND NEPHROTOXICITY ASSESSMENT (2011) (5)
Abstract 4920: Gene network models identify targets for mammary tumor normalization (2012) (5)
Pictures in cell biology: squaring up to the cell-shape debate. (1999) (5)
Molecular mapping of transmembrane mechanotransduction through the β1 integrin-CD98hc-TRPV4 axis. (2020) (5)
LRP 5 Regulates Development of Lung Microvessels and Alveoli through the Angiopoietin-Tie 2 Pathway (2012) (5)
Purified and Recombinant Hemopexin: Protease Activity and Effect on Neutrophil Chemotaxis (2016) (5)
Tensegrity and the Emergence of Complex Mechanical Behavior in Living Cells (2000) (5)
Disruption of tensegrity in vimentin-deficient fibroblasts causes delayed wound healing in fetal and adult mice (1998) (4)
Angiogenic Vascular Grafts1 (1987) (4)
Target-agnostic discovery of Rett Syndrome therapeutics by coupling computational network analysis and CRISPR-enabled in vivo disease modeling (2022) (4)
Bioinspired Environmental Coordination in Spatial Computing Systems (2008) (4)
Discovery of TNP-470 and Other Angiogenesis Inhibitors (1997) (4)
Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology (2020) (4)
Developmentally Inspired Regenerative Organ Engineering: Tooth as a Model (2015) (4)
Mechanobiology, Tissue Development and Organ Engineering (2014) (4)
CHAOTIC MEAN FIELD DYNAMICS OF A BOOLEAN NETWORK WITH RANDOM CONNECTIVITY (2007) (4)
Establishment of physiologically relevant oxygen gradients in microfluidic organ chips (2022) (4)
Integrinbindingand mechanical tension induce movement ofmRNAand ribosomesto focal adhesions (1998) (4)
Biofabrication of Multiplexed Electrochemical Immunosensors for Simultaneous Detection of Clinical Biomarkers in Complex Fluids (2022) (4)
Self-Adaptive Furniture with a Modular Robot (2007) (4)
A bioinspired surface coating for medical devices that prevents thrombosis and biofouling (2014) (4)
Broad spectrum capture of clinical pathogens using engineered Fc-Mannose-Binding Lectin (FcMBL) enhanced by antibiotic treatment (2018) (3)
Enabling out-of-body experiences for living organs (2021) (3)
Modular biomaterials vaccine technology protects against multiple pathogens and septic shock (2020) (3)
Lymphoid follicle formation and human vaccination responses recapitulated in an organ-on-a-chip (2019) (3)
Molecular mapping of transmembrane mechanotransduction through the β1 integrin–CD98hc–TRPV4 axis (2020) (3)
Self-assembling short immunostimulatory duplex RNAs with broad spectrum antiviral activity (2021) (3)
Simultaneous detection of SARS-CoV-2 RNA and host antibodies enabled by a multiplexed electrochemical sensor platform (2021) (3)
New recommended policies for pathogen surveillance testing of researchers and improved stewardship of diagnostic DNA (2020) (3)
ResearchArticle Towards a Holistic, Yet Gene-Centered Analysis of Gene Expression Profiles: A Case Study of Human Lung Cancers (2006) (3)
Rapid antifouling nanocomposite coating enables highly sensitive multiplexed electrochemical detection of myocardial infarction and concussion markers (2021) (3)
Tensegrity as a Mechanism for Integrating Molecular and Cellular Mechanotransduction Mechanisms (2009) (3)
Using femtosecond laser subcellular surgery to studycell biology (2004) (3)
Detection of Pathogens with Impedance Analysis in a Lab on a Chip (2011) (3)
BONE MARROW-ON-A-CHIP (2012) (3)
Developing Microphysiological Systems for Use as Regulatory Tools - Supplementary File (2014) (3)
Micromechanical Design Criteria for Tissue Engineering Biomaterials (2013) (3)
The Wyss Institute for Biologically Inspired Engineering (2013) (3)
Establishment of a Modular Anaerobic Human Intestine Chip. (2021) (3)
Chapter Fifteen – Mechanochemical Control of Cell Fate Switching (2007) (3)
Music therapy: tune-up for mind and body. (1982) (3)
Development of a human COPD model-on-a-chip to mimic disease exacerbation (a small airway-on-a-chip model) (2014) (3)
Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip (2018) (3)
Cell Interactions With Fibronectin-Coated Electrically Conducting Polypyrrole Thin Films (1993) (2)
Biologically Inspired, iterative engineering of a Human Lymphoid Follicle Chip (2018) (2)
Endothelial Biomedicine: Vascular Control through Tensegrity-Based Integration of Mechanics and Chemistry (2007) (2)
Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches (2022) (2)
Nutritional deficiency recapitulates intestinal injury associated with environmental enteric dysfunction in patient-derived Organ Chips (2021) (2)
Tissue Engineered Human Blood-Retinal Barrier-on-a-Chip (2016) (2)
Pre-stressed Tensegrity Structures built from DNA (2009) (2)
A Chemical APC Mimetic Protects Endothelium from Thromboinflammatory Injury (2016) (2)
Rapid quantitation of SARS-CoV-2 antibodies in clinical samples with an electrochemical sensor (2022) (2)
Endothelial cilia are mechanosensory organelles (2008) (2)
Chitosan‐Fibroin Laminates: Unexpected Strength and Toughness in Chitosan‐Fibroin Laminates Inspired by Insect Cuticle (Adv. Mater. 4/2012) (2012) (2)
Interview with Donald E Ingber. (2014) (2)
Tensegrity and the Emergence of a Cellular Biophysics (1998) (2)
Extracellular Matrix: A Solid-State Regulator of Cell form, Function, and Tissue Development (2011) (2)
Anti‐Compression and Anti‐Angiogenic Therapy for Breast Cancer (2015) (2)
A Mechanochemical Microarray for Studying Combinatorial Effects on Embryonic Mesenchymal Cell Differentiation (2016) (2)
Magnetic Separation: Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles (Small 42/2015) (2015) (1)
Biophysics-Enabled Translational Medicine (2018) (1)
4 CELLULAR TENSEGRITY MODELS AND CELL-SUBSTRATE INTERACTIONSSTAMENOVI ´ (2006) (1)
Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human endo- and ecto-cervix chips (2023) (1)
Author Correction: A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip (2019) (1)
PIKfyve-specific inhibitors restrict replication of multiple coronaviruses in vitro but not in a murine model of COVID-19 (2022) (1)
Mapping Elasticity Down to the Molecular Scale: a Novel High-Resolution Approach to Study Cell Mechanics (2010) (1)
Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches (Adv. Sci. 26/2022) (2021) (1)
Magnetic Separation: Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles (Small 42/2015) (2015) (1)
Treatment with RHO kinase inhibitor Y27632 results in decreased lung branching morphogenesis (2000) (1)
Magnetic Separation: Optimization of Pathogen Capture in Flowing Fluids with Magnetic Nanoparticles (Small 42/2015) (2015) (1)
Assessment of whole blood thrombosis in a microfluidic device lined by fixed human endothelium (2016) (1)
Electrical simulations and experimental results of 4-electrode AC transepithelial electrical resistance measurements in gut-on-a-chip (2017) (1)
Activation of mechanosensitive ion channel TRPV4 promotes normalization of tumor vasculature and improves cancer therapy (893.12) (2014) (1)
Abstract 2025: Prevention of mammary tumor progression via intraductal injection of nanoparticle-formulated siRNA. (2013) (1)
Nanosurgery in live cells using ultrashort laser pulses (2005) (1)
Predicting drug concentrations in PDMS microfluidic organ chips (2021) (1)
Interview with Donald E. Ingber JULY 2002 (2008) (1)
Supporting Information for Paper-Supported Three-Dimensional Cell Culture for Tissue-Based Bioassays (2009) (1)
A complex systems approach to understand how cells control their shape and make cell fate decisions (2005) (1)
Human small airway-on-a-chip: A novel microphysiological system to model lung inflammation, accelerate drug development and enable inhalational toxico-analysis (2016) (1)
Interview of Don Ingber with Albert van den Berg and Andries van der Meer (University of Twente, the Netherlands, and EUROoCs board members). (2021) (1)
Self-assembling short immunostimulatory duplex RNAs with broad-spectrum antiviral activity (2022) (1)
Basement Membrane Polarizes Epithelial Cells and Its Loss Can Result in Neoplastic Disorganization (Cell Shape, Cancer, Morphogenesis) (1984) (1)
Platelet-rich Plasma Extract Accelerates Lung Regeneration Through the LRP5-Tie2 Pathway. (2015) (1)
653. Diagnosis of Burn Sepsis Using the FcMBL ELISA: A Pilot Study in Critically Ill Burn Patients (2019) (1)
Reproductive endocrinology: Cycling through the menstrual cycle — an out-of-body experience (2017) (1)
Cell Attachment and Protein Adsorption to Polypyrrole thin Films (1992) (1)
Electrochemical Biosensors: Graphene Enabled Low‐Noise Surface Chemistry for Multiplexed Sepsis Biomarker Detection in Whole Blood (Adv. Funct. Mater. 16/2021) (2021) (1)
Supplemental Material : Programmed death is favored by natural selection in spatial systems (2015) (1)
Interdisciplinarity and mechanobiology (2022) (1)
Viscoelastic Indentation of Extremely Soft Biological Samples (2009) (1)
Bioinspired design and optimization for thin film wearable and building cooling systems (2021) (1)
Low cost, injection molded, nasopharyngeal swabs for addressing global diagnostic supply shortages (2021) (1)
Control of endothelial focal adhesions by cell shape (1999) (1)
Putting the Cell Biology Establishment on the Stand (2002) (1)
SURFACE MODIFICATION WITH ENGINEERED BACTERIAL BIOCOMPATIBLE NANOMATERIALS FOR CELL PROLIFERATION (2009) (0)
Increased phosphorylation of ACTN4 leads to podocyte vulnerability and proteinuric kidney disease and is stimulated by high glucose and TGF‐b (2020) (0)
Targeted Drug Delivery to Flow-Obstructed Blood Vessels UsingMechanically Activated Nanotherapeutics (2015) (0)
Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients. (2023) (0)
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids (2018) (0)
Sub-Cellular Nanosurgery in Live Cells Using Ultrashort Laser Pulses (2005) (0)
Ectopic Lymphoid Follicle Formation and Human Seasonal Influenza Vaccination Responses Recapitulated in an Organ‐on‐a‐Chip (Adv. Sci. 14/2022) (2022) (0)
Mechanotransduction and Developmental Control (2011) (0)
Knowing IC FLUX CONCENTRATOR DEVIC D VISUALIZATION OF PATHOGE (2011) (0)
Robotic fluidic coupling and interrogation of multiple vascularized organ chips (2020) (0)
A human ectopic-lymphoid-follicle-on-a-chip for testing vaccines and adjuvants (2022) (0)
Angiogenesis Research to Improve Therapies for Vascular Leak Syndromes, Intra-Abdominal Adhesions, and Arterial Injuries (2009) (0)
A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip (2019) (0)
In search of cellular control: signal transduction in context. (1998) (0)
Control of Capillary Cell Growth, Survival, and Contractility by Caldesmon in Angiogenesis (2003) (0)
Synthesis and Manipulation of Biofunctional Magnetic Particles (2007) (0)
Reviews of "Intestinal receptor of SARS-CoV-2 in inflamed IBD tissue is downregulated by HNF4A in ileum and upregulated by interferon regulating factors in colon" (2020) (0)
Device imitation organs microchannel and methods of use (2009) (0)
Mechanosensitive control of VEGFR2 transcription and angiogenesis through antagonism between GATA2 and TFII‐I (2009) (0)
Nanodroplet array for multiplexed single-cell assays (2013) (0)
Epithelial-Stromal Interactions in Barrett’s Esophagus Modeled in Human Organ Chips (2023) (0)
Prevention of the Angiogenic Switch in Human Breast Cancer (2009) (0)
Circulating Tumor Cells: An Engineered Human Fc‐Mannose‐Binding‐Lectin Captures Circulating Tumor Cells (Adv. Biosys. 7/2017) (2017) (0)
Cover Picture: Macromol. Mater. Eng. 8/2014 (2014) (0)
The Rho inhibitor p190RhoGAP controls VEGFR2 transcription and angiogenesis in vitro through antagonism between GATA2 and TFII‐I (2008) (0)
Caldesmon regulates apoptosis and cell cycle progression in capillary endothelial cells and inhibits angiogenesis in vitro (2003) (0)
Synthesis of Cortistatin Analogues (2009) (0)
Angiogenesis inhibiting agent. (1989) (0)
A bone marrow-ona-chip that maintains hematopoietic regenerative capacity in vitro (2013) (0)
SEBS elastomers for fabrication of microfluidic devices with reduced drug absorption by injection molding and extrusion (2017) (0)
Pharmacodynamics Analysis Using Organs-on-Chips (2016) (0)
Cyst‐lining epithelial cells from ADPKD kidneys have a mechano‐ciliary dysfunction (2006) (0)
A miniaturized clark oxygen sensor for organ-on-chip devices (2018) (0)
Modelling cancer in microfluidic human organs-on-chips (2019) (0)
EXTRACELLULAR-MATRIX (ECM) REGULATES PULMONARY ARTERIAL SMOOTH-MUSCLE CELL (PASMC) GROWTH (1993) (0)
Role of Hemoxygenase-1 as a Central Mediator of Acute Radiation Pneumonitis Revealed in a Human Lung Alveolus-on-a-Chip (2023) (0)
Amy Brock Prevents Mammary Tumor Progression in Mice by Intraductal Injection of siRNA Lipidoid Nanoparticles HoxA 1 Silencing (2013) (0)
Geometric preferences of lamellipodia extension (1999) (0)
Abstract 4924: Gene network inference models reveal novel key mediators of mammary tumorigenesis (2011) (0)
Reply (2013) (0)
Changes in ABC Transporter Expression during Hematopoiesis Cause Lineage-Biased Cytopenias in Patients Treated with Aurora Kinase Inhibitors (2021) (0)
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip (2018) (0)
Biomaterial vaccines capturing pathogen-associated molecular patterns protect against bacterial infections and septic shock (2021) (0)
Identification of a pharmaceutical biostasis inducer that slows metabolism in multiple vertebrates that do not hibernate (2023) (0)
Chapter 15. Computational Biophysics (2009) (0)
Focal Adhesions: Self‐Assembling Nanoscale Mechanochemical Machines that Control Cell Function (2007) (0)
AFM Visualization and Force Spectroscopy of Clathrin Triskelia (2009) (0)
Modeling mucus physiology and pathophysiology in human organs-on-chips. (2022) (0)
Angiogenesis and Tissue Engineering Research (2010) (0)
A Novel Self-Assembled, Self-Healing, Ordered Biomaterial (2009) (0)
Author Correction: A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip (2019) (0)
Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology (2023) (0)
Abstract 342: Analysis of Mechanism of a Novel Drug Candidate using an Organ-level Functional Microdevice that Reconstitutes Human Pulmonary Thrombosis (2016) (0)
NON-ABSORBING, CLEAR, FLEXIBLE, AND CASTABLE POLYURETHANE FOR FABRICATION OF MICROFLUIDIC DEVICES (2011) (0)
Molecular signaling: breakout session summary. (2002) (0)
Modeling Severe Influenza Viral Infection Using a Human Lung Alveolus Chip (2020) (0)
Abstract B102: A microengineered human lymph node-on-a-chip to study cancer immunotherapy (2016) (0)
Generation of a cellular Yin-Yang pattern (2000) (0)
Differential ABC transporter expression during hematopoiesis contributes to neutrophil-biased toxicity of Aurora kinase inhibitors (2022) (0)
Microengineered Human Gut‐on‐a‐Chip for Dissecting Intestinal Inflammatory Disease (2015) (0)
Biochemical and Hematologic Reference Intervals for Anesthetized, Female, Juvenile Yorkshire Swine. (2021) (0)
Seeing Your Way to New Insights in Biology. (2019) (0)
On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology (2020) (0)
Hemoxygenase-1 as a key mediator of acute radiation pneumonitis revealed in a human lung alveolus-on-a-chip (2023) (0)
Reply: To PMID 23711562. (2014) (0)
From Stem Cells to Functional Tissue Architecture: What Are the Signals and How Are They Processed? (2003) (0)
Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies (2019) (0)
Fibronectin unfolding revisited: modeling physiological unfolding mechanisms of fibronectin’s tenth repeat of type III with steered molecular dynamics simulations (2007) (0)
Author Correction: On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology (2020) (0)
Tumor, angiogenesis and fumagillin (1991) (0)
Mechanosensation Mediates Long‐Range Spatial Decision‐Making in an Aneural Organism (Adv. Mater. 34/2021) (2021) (0)
Human Lung Chip-Based Disease Models for Efficacy Testing (2020) (0)
Mechanosensation Mediates Long‐Range Spatial Decision‐Making in an Aneural Organism (2021) (0)
Engineered Mannose‐Binding Lectin (FcMBL) Decreases Macrophage Phagocytosis (2016) (0)
Mechanotransduction through Integrins (2004) (0)
Investigating the local mechanical properties of cells using microinjected colloidal particles (2003) (0)
TRPV4 channels regulate tumor angiogenesis through the modulation of Rho‐dependent tumor endothelial cell mechanosensitivity (2012) (0)
Rapid quantitative electrochemical detection of SARS-CoV-2 antibodies in plasma and dried blood spot samples (2022) (0)
Immobilized plasminogen activator inhibitor-1 (pai-1) mediates cell adhesion, spreading and cytoskeletal reorganization (1996) (0)
Fibrillogenesis Domain Initiates Fibronectin SLLISWD Sequence in the 10 FNIII Glycobiology and Extracellular Matrices : (2013) (0)
Abstract 168: Esophageal adenocarcinoma-on-a-chip; modeling patient specific disease progression and a step towards functional precision oncology (2023) (0)
Estrogen-receptor-α exchange and chromatin dynamics are ligand- and domain-dependent (2006) (0)
生命のア-キテクチャ---生物のかたちを決める力 (1998) (0)
deformability in adherent endothelial cells? Is cytoskeletal tension a major determinant of cell (2013) (0)
NATURE ' MTHODS '' in ' press ' Small airway-ona-chip enables analysis of human lung inflammation and therapeutic responses in vitro (2016) (0)
Organs-on-chips for toxicity testing: lung-thrombosis chip as a practical example (2018) (0)
Biomagnetics and Cell-Based Biochips (2005) (0)
Abstract 3273: A robust transgenic mouse model to study male breast cancer (2012) (0)
A BioSpleen Blood Cleansing Device for Sepsis Therapy (2015) (0)
Decoupling sensitivity and dynamic range : electrokinetically driven microfluidic impedance immunosensor with 3 D antibody immobilization (2017) (0)
Characterizing Host-Pathogen Interactions in Cystic Fibrosis Airway on a Chip Model (2020) (0)
From tensegrity to human organs-on-chips: implications for mechanobiology and mechanotherapeutics (2023) (0)
Enhancement of experimental lung metastases by melanoma cells treated with icrf-159. Abstr. (1978) (0)
Correction (2005) (0)
angiogenesis by altering Neuropilin2 expression (2014) (0)
Stretch-activated calcium channels mediate cyclic strain-induced endothelial cell orientation by controlling activation of beta 1 integrin and RhoA (2007) (0)
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips (2020) (0)
FcMBL magnetic bead-based MALDI-TOF MS rapidly identifies paediatric blood stream infections from positive blood cultures (2022) (0)
Abstract WP437: Shear-activated Nanoparticle Aggregate Lysis Combined With Temporary Stent-bypass to Treat Emergent Large Vessel Occlusions (ELVO) (2016) (0)
Stress‐activated TRPV4 channels mediate integrin to integrin mechanical signaling that is required for angiogenesis (2008) (0)
Development of New Approaches for Breast Cancer Therapy and Diagnosis Based on Angiogenesis (1996) (0)
Different HMGCR-inhibiting statins vary in their association with increased survival in patients with COVID-19 (2022) (0)
BRIDGING THE CHASM BETWEEN DEVELOPMENTAL BIOLOGY AND TISSUE ENGINEERING (2006) (0)
INTEGRATED MULTI-ELECTRODE ARRAY AND TRANS-ENDOTHELIAL ELECTRICAL RESISTANCE IN ORGAN-ON-A-CHIP MICROSYSTEMS (2018) (0)
Mechanotransduction through Cytoskeleton (2002) (0)
Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites (2019) (0)
Cell Motility in Microfabricated Models of the Tissue Microenvironment (2001) (0)
Abstract 520: Local changes in tissue microenvironment regulate mammary tumor progression (2011) (0)
-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the (cid:1) 4 -cytoplasmic domain (2005) (0)
Author Correction: Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology (2023) (0)
Abstract A76: Microenginered human lymphoid tissue on chip (2018) (0)
Multiplexed Detection of Sepsis Markers in Whole Blood using Nanocomposite Coated Electrochemical Sensors (2020) (0)
Abstract P5-05-04: Intraductal delivery of RNAi-based therapeutics to gene targets identified through computational systems modeling (2012) (0)

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