J. Michael Bishop | Academic Influence

J. Michael Bishop's AcademicInfluence.com Rankings

J. Michael Bishop

Biology

#201

World Rank

#367

Historical Rank

#116

USA Rank

Microbiology

#38

World Rank

#54

Historical Rank

#23

USA Rank

Immunology

#57

World Rank

#63

Historical Rank

#22

USA Rank

biology Degrees

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Biology

J. Michael Bishop's Degrees

Doctorate Medicine Harvard University
Bachelors Chemistry Gettysburg College

Why Is J. Michael Bishop Influential?

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According to Wikipedia, John Michael Bishop is an American immunologist and microbiologist who shared the 1989 Nobel Prize in Physiology or Medicine with Harold E. Varmus and was co-winner of 1984 Alfred P. Sloan Prize. He serves as an active faculty member at the University of California, San Francisco , where he also served as chancellor from 1998 to 2009.

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J. Michael Bishop's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product (1985) (2442)
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. (1984) (2232)
Molecular themes in oncogenesis (1991) (1626)
Cellular oncogenes and retroviruses. (1983) (1505)
Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour (1983) (1404)
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA (1976) (1283)
The molecular genetics of cancer. (1987) (1238)
Reversible tumorigenesis by MYC in hematopoietic lineages. (1999) (872)
Senescence of human fibroblasts induced by oncogenic Raf. (1998) (852)
MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer (2004) (828)
Targeted expression of MYCN causes neuroblastoma in transgenic mice (1997) (804)
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma. (1983) (677)
Sustained Loss of a Neoplastic Phenotype by Brief Inactivation of MYC (2002) (658)
The MYC protein activates transcription of the alpha‐prothymosin gene. (1991) (592)
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein (1978) (554)
The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. (2012) (545)
Multiple arrangements of viral DNA and an activated host oncogene in bursal lymphomas (1982) (528)
Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch. (1999) (516)
c-Myc regulates mammalian body size by controlling cell number but not cell size (2001) (460)
Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells (1989) (456)
Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: The architecture of a transduced oncogene (1982) (445)
Definition of regions in human c-myc that are involved in transformation and nuclear localization (1987) (436)
Transient excess of MYC activity can elicit genomic instability and tumorigenesis. (1999) (426)
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells (1983) (419)
Correct integration of retroviral DNA in vitro (1987) (419)
A PMLRARα transgene initiates murine acute promyelocytic leukemia (1997) (419)
Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening. (1999) (418)
Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2 (1997) (408)
A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle (1990) (404)
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma. (1984) (400)
A nucleoprotein complex mediates the integration of retroviral DNA. (1989) (379)
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase (1993) (372)
Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues (1982) (369)
Retroviral integration: structure of the initial covalent product and its precursor, and a role for the viral IN protein. (1989) (367)
Macrophages are required for cell death and tissue remodeling in the developing mouse eye (1993) (366)
Short RNA duplexes produced by hydrolysis with Escherichia coli RNase III mediate effective RNA interference in mammalian cells (2002) (330)
Standardized and simplified nomenclature for proteins common to all retroviruses (1988) (326)
Mapping unintegrated avian sarcoma virus DNA: Termini of linear DNA bear 300 nucleotides present once or twice in two species of circular DNA (1978) (323)
Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc (1984) (311)
Isolation and characterization of c-myc, a cellular homolog of the oncogene (v-myc) of avian myelocytomatosis virus strain 29 (1982) (307)
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src). (1979) (297)
Proviruses of avian sarcoma virus are terminally redundant, co-extensive with unintegrated linear DNA and integrated at many sites (1978) (294)
Molecular cloning and characterization of avian sarcoma virus circular DNA molecules (1980) (294)
Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state (1981) (293)
Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC (2007) (290)
Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src). (1981) (289)
Activation of the Met Receptor by Cell Attachment Induces and Sustains Hepatocellular Carcinomas in Transgenic Mice (2001) (278)
Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product (1980) (275)
Enemies within: the genesis of retrovirus oncogenes (1981) (268)
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2 (1997) (262)
Isolation and characterization of chicken DNA homologous to the two putative oncogenes of avian erythroblastosis virus (1982) (262)
Identification of a human gene (HCK) that encodes a protein-tyrosine kinase and is expressed in hemopoietic cells (1987) (258)
Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae (1995) (251)
Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene. (1991) (247)
Virus-Specific Ribonucleic Acid in Cells Producing Rous Sarcoma Virus: Detection and Characterization (1972) (245)
The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane. (1980) (243)
DNA and RNA from Uninfected Vertebrate Cells Contain Nucleotide Sequences Related to the Putative Transforming Gene of Avian Myelocytomatosis Virus (1979) (241)
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture (1985) (238)
Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex (2002) (237)
Dexamethasone-mediated induction of mouse mammary tumor virus RNA: a system for studying glucocorticoid action (1975) (237)
Purification of DNA complementary to nucleotide sequences required for neoplastic transformation of fibroblasts by avian sarcoma viruses. (1976) (235)
Cellular functions are required for the synthesis and integration of avian sarcoma virus-specific DNA (1977) (218)
Nucleotide sequences related to the transforming gene of avian sarcoma virus are present in DNA of uninfected vertebrates. (1978) (215)
Enteropathogenic E. coli acts through WASP and Arp2/3 complex to form actin pedestals (1999) (214)
A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein. (1981) (206)
Cell division and cell survival in the absence of survivin. (2004) (198)
Identification of nuclear proteins encoded by viral and cellular myc oncogenes (1983) (196)
The size and genetic composition of virus-specific RNAs in the cytoplasm of cells producing avian sarcoma-leukosis viruses (1977) (192)
Mitosis-specific phosphorylation of p60c-src by p34 cdc2-associated protein kinase (1989) (192)
Glucocorticoid-stimulated accumulation of mouse mammary tumor virus RNA: increased rate of synthesis of viral RNA. (1977) (192)
Distinct pathways of genomic progression to benign and malignant tumors of the liver (2007) (191)
Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA (1983) (190)
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine. (1980) (189)
Expression of CD44 is repressed in neuroblastoma cells (1991) (185)
Proposal for Naming Host Cell-Derived Inserts in Retrovirus Genomes (1981) (183)
Aberrant expression of an amplified c-myb oncogene in two cell lines from a colon carcinoma. (1984) (175)
Subcellular localization of proteins encoded by oncogenes of avian myeloblastosis virus and avian leukemia virus E26 and by the chicken c-myb gene (1984) (172)
The protein encoded by the human proto-oncogene c-myc. (1984) (169)
MYC Suppresses Cancer Metastasis by Direct Transcriptional Silencing of αv and β3 Integrin Subunits (2012) (168)
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb (1989) (168)
A PMLRARalpha transgene initiates murine acute promyelocytic leukemia. (1997) (166)
The nucleotide sequence and the tissue-specific expression of Drosophila c-src (1985) (166)
Contrasting patterns of myc and N-myc expression during gastrulation of the mouse embryo. (1989) (164)
Nestin‐Cre transgenic mouse line Nes‐Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite‐derived tissues (2006) (164)
Expression of N-myc in teratocarcinoma stem cells and mouse embryos (1985) (161)
Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase (2010) (160)
Transcription of DNA from the 70S RNA of Rous Sarcoma Virus I. Identification of a Specific 4S RNA Which Serves as Primer (1974) (160)
Retroviruses and cancer genes. (1982) (159)
Molecular cloning of the avian myelocytomatosis virus genome and recovery of infectious virus by transfection of chicken cells (1981) (157)
Molecular cloning of the avian erythroblastosis virus genome and recovery of oncogenic virus by transfection of chicken cells (1980) (155)
Mutations of the Kirsten-ras proto-oncogene in human preleukaemia (1987) (154)
A joint product of the genes gag and pol of Avian Sarcoma Virus: a possible precursor of reverse transcriptase (1977) (154)
Transcription of mouse mammary tumor virus genes in tissues from high and low tumor incidence mouse strains. (1973) (154)
Transforming genes in chronic myelogenous leukemia. (1988) (154)
Transduction of a cellular oncogene: the genesis of Rous sarcoma virus. (1983) (153)
Nucleotide sequence of the human N-myc gene. (1986) (152)
The product of the protooncogene c-src is modified during the cellular response to platelet-derived growth factor. (1985) (152)
The product of the retroviral transforming gene v-myb is a truncated version of the protein encoded by the cellular oncogene c-myb (1983) (152)
The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans (2007) (151)
A screen for genes that suppress loss of contact inhibition: identification of ING4 as a candidate tumor suppressor gene in human cancer. (2004) (151)
The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related (1983) (150)
Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60 v-src and pp60 c-src (1984) (148)
Identification of nucleotide sequences which may encode the oncogenic capacity of avian retrovirus MC29 (1978) (148)
Production of mouse mammary tumor virus by cultured cells in the absence and presence of hormones: assay by molecular hybridization. (1975) (144)
Overexpression of MYC causes p53-dependent G2 arrest of normal fibroblasts. (2000) (140)
Neurotrophin–3 is required for proper cerebellar development (1999) (136)
Blocked, methylated 5′-terminal sequence in avian sarcoma virus RNA (1975) (134)
Cellular adherence elicits ligand-independent activation of the Met cell-surface receptor. (1996) (133)
9 Functions and Origins of Retroviral Transforming Genes (1982) (131)
Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29. (1983) (131)
Identification of a large Myc-binding protein that contains RCC1-like repeats. (1998) (129)
The first seven amino acids encoded by the v-src oncogene act as a myristylation signal: lysine 7 is a critical determinant (1988) (129)
Na+ and K+ concentrations and the regulation of protein synthesis in Sindbis virus-infected chick cells. (1979) (129)
A human gene (AHNAK) encoding an unusually large protein with a 1.2-microns polyionic rod structure. (1992) (127)
Transit of pp60v-src to the plasma membrane. (1982) (126)
Predisposition to neoplastic transformation caused by gene replacement of H-ras1. (1993) (125)
Heterogeneity of genetic loci in chickens: analysis of endogenous viral and nonviral genes by cleavage of DNA with restriction endonucleases (1979) (124)
Detection of avian tumor virus-specific nucleotide sequences in avian cell DNAs (reassociation kinetics-RNA tumor viruses-gas antigen-Rous sarcoma virus, chick cells). (1972) (124)
The low molecular weight RNAs of Rous sarcoma virus: II. The 7 S RNA (1970) (123)
Mammary tumour virus specific nucleotide sequences in mouse DNA. (1972) (123)
Isolation of the proto-oncogene c-myb from D. melanogaster (1985) (121)
Comparison of mouse mammary tumor virus-specific DNA in inbred, wild and Asian mice, and in tumors and normal organs from inbred mice. (1977) (121)
Integration of Deoxyribonucleic Acid Specific for Rous Sarcoma Virus after Infection of Permissive and Nonpermissive Hosts (1973) (120)
Bcl-2 Cooperates with Promyelocytic Leukemia Retinoic Acid Receptor α Chimeric Protein (Pmlrarα) to Block Neutrophil Differentiation and Initiate Acute Leukemia (2001) (119)
Neoplastic transformation by the human gene N-myc (1987) (118)
Ethidium bromide inhibits appearance of closed circular viral DNA and integration of virus-specific DNA in duck cells infected by avian sarcoma virus (1975) (117)
Phosphorylation of the fused protein kinase in response to signaling from hedgehog. (1996) (117)
Kinetics of synthesis, structure and purification of avian sarcoma virus-specific DNA made in the cytoplasm of acutely infected cells. (1978) (115)
Diamond‐Lipid Hybrids Enhance Chemotherapeutic Tolerance and Mediate Tumor Regression (2013) (114)
Human proto-oncogene N-myc encodes nuclear proteins that bind DNA (1986) (113)
The src protein contains multiple domains for specific attachment to membranes (1990) (113)
A mutation at the ATP-binding site of pp60v-src abolishes kinase activity, transformation, and tumorigenicity (1985) (112)
Id1 cooperates with oncogenic Ras to induce metastatic mammary carcinoma by subversion of the cellular senescence response (2008) (110)
Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP‐mediated recombination in the mouse (2000) (110)
Regulatory elements that modulate expression of human c-myc. (1987) (109)
Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src). (1981) (108)
Phosphorylation of tyrosine-416 is not required for the transforming properties and kinase activity of pp60v-src (1983) (107)
Appearance of virus-specific DNA in mammalian cells following transformation by Rous sarcoma virus. (1973) (104)
Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements. (1981) (103)
Activated Notch1 induces lung adenomas in mice and cooperates with Myc in the generation of lung adenocarcinoma. (2011) (102)
Corrections to the nucleotide sequence of the src gene of Rous sarcoma virus (1983) (102)
Synthesis of a deoxyribonucleic acid sequence complementary to ovalbumin messenger ribonucleic acid and quantification of ovalbumin genes. (1973) (102)
Cancer: the rise of the genetic paradigm. (1995) (101)
MET and MYC cooperate in mammary tumorigenesis. (2005) (100)
RNA-directed DNA synthesis by virions of Rous sarcoma virus: further characterization of the templates and the extent of their transcription. (1973) (99)
Src interacts with dynamin and synapsin in neuronal cells. (1998) (99)
Uninfected avian cells contain RNA related to the transforming gene of avian sarcoma viruses (1978) (98)
Transcriptional activation by the v-myb oncogene and its cellular progenitor, c-myb. (1989) (98)
A FOS protein is present in a complex that binds a negative regulator of MYC. (1989) (97)
Purification and characterization of poliovirus-induced infectious double-stranded ribonucleic acid. (1967) (95)
Torso, a receptor tyrosine kinase required for embryonic pattern formation, shares substrates with the sevenless and EGF-R pathways in Drosophila. (1993) (94)
Purification and characterization of the deoxyribonucleic acid polymerase associated with Rous sarcoma virus. (1972) (94)
DNA Polymerases of Rous Sarcoma Virus: Delineation of Two Reactions with Actinomycin (1970) (94)
A putative protein kinase gene (kin1+) is important for growth polarity in Schizosaccharomyces pombe. (1990) (93)
The product of the avian erythroblastosis virus erbB locus is a glycoprotein (1983) (93)
Site-specific mutagenesis of avian erythroblastosis virus: erb-B is required for oncogenicity. (1983) (93)
The B Cell Antigen Receptor and Overexpression of MYC Can Cooperate in the Genesis of B Cell Lymphomas (2008) (92)
Directed establishment of rat brain cell lines with the phenotypic characteristics of type 1 astrocytes. (1992) (91)
Leukemia initiated by PMLRARalpha: the PML domain plays a critical role while retinoic acid-mediated transactivation is dispensable. (2000) (91)
Cellular homologue (c-src) of the transforming gene of Rous sarcoma virus: isolation, mapping, and transcriptional analysis of c-src and flanking regions. (1981) (91)
Cancer genes come of age (1983) (89)
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma. (1989) (88)
Structure of viral DNA and RNA in mammalian cells infected with avian sarcoma virus. (1980) (88)
Synthesis of viral DNA in the cytoplasm of duck embryo fibroblasts and in enucleated cells after infection by avian sarcoma virus. (1974) (87)
Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virus. (1981) (87)
Oncogene‐specific formation of chemoresistant murine hepatic cancer stem cells (2012) (86)
Drosophila myb is required for the G2/M transition and maintenance of diploidy. (1998) (84)
Subcellular location of an abundant substrate (p36) for tyrosine-specific protein kinases. (1983) (84)
Deoxyribonucleic Acid Polymerase Associated with Rous Sarcoma Virus and Avian Myeloblastosis Virus: Properties of the Enzyme and Its Product (1970) (83)
Nucleotide sequence at the 5' terminus of the avian sarcoma virus genome. (1977) (83)
The PVT gene frequently amplifies with MYC in tumor cells (1989) (82)
Characterization of the Low-Molecular-Weight RNAs Associated with the 70S RNA of Rous Sarcoma Virus (1973) (82)
RNA-directed DNA polymerase of Rous sarcoma virus: initiation of synthesis with 70 S viral RNA as template. (1973) (82)
Organization of the endogenous proviruses of chickens: implications for origin and expression. (1981) (81)
The human gene AHNAK encodes a large phosphoprotein located primarily in the nucleus (1993) (80)
Effects of translocations on transcription from PVT (1990) (80)
The vertebrate homolog of the putative transforming gene of avian myelocytomatosis virus: characteristics of the DNA locus and its RNA transcript. (1980) (79)
Isolation of monoclonal antibodies specific for products of avian oncogene myb (1984) (78)
Hedgehog-stimulated Phosphorylation of the Kinesin-related Protein Costal2 Is Mediated by the Serine/Threonine Kinase Fused* (2002) (77)
Negative Control of the Myc Protein by the Stress-Responsive Kinase Pak2 (2004) (77)
Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16. (1994) (77)
Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila (1983) (76)
Purification and enzymatic characterization of pp60c-src from human platelets. (1990) (76)
Structure of the protein encoded by the chicken proto-oncogene c-myb (1986) (75)
Inactivation of a c-Myb/estrogen receptor fusion protein in transformed primary cells leads to granulocyte/macrophage differentiation and down regulation of c-kit but not c-myc or cdc2 (1997) (75)
Extent of transcription by the RNA-dependent DNA polymerase of Rous sarcoma virus. (1971) (75)
Transcription of DNA from the 70S RNA of Rous Sarcoma Virus II. Structure of a 4S RNA Primer (1974) (75)
Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle (1992) (74)
Characteristics of cellular RNA related to the transforming gene of avian sarcoma viruses (1978) (73)
Isolation of duplicated human c-src genes located on chromosomes 1 and 20 (1985) (73)
PML-RARA–targeted DNA vaccine induces protective immunity in a mouse model of leukemia (2003) (73)
Infectious replicative intermediate of poliovirus: purification and characterization. (1969) (72)
The PEBP2betaMYH11 fusion created by Inv(16)(p13;q22) in myeloid leukemia impairs neutrophil maturation and contributes to granulocytic dysplasia. (1998) (72)
Synthesis, structure and function of avian sarcoma virus-specific DNA in permissive and nonpermissive cells. (1975) (70)
Two yeast genes that encode unusual protein kinases. (1987) (68)
Amplification and enhanced expression of the c-myc oncogene in mouse SEWA tumour cells (1985) (68)
Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130. (1999) (67)
Structure and transcription of the cellular homolog (c-myb) of the avian myeloblastosis virus transforming gene (v-myb) (1983) (66)
A 3' truncation of MYC caused by chromosomal translocation in a human T-cell leukemia increases mRNA stability. (1990) (66)
Ras family GTPases control growth of astrocyte processes. (1999) (65)
DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc. (1989) (65)
Inhibition of RNA-dependent DNA polymerase of Rous sarcoma virus by thiosemicarbazones and several cations. (1973) (64)
Virus-specific RNAs in cells infected by avian myelocytomatosis virus and avian erythroblastosis virus: Modes of oncogene expression (1981) (63)
A Rous sarcoma virus provirus is flanked by short direct repeats of a cellular DNA sequence present in only one copy prior to integration. (1981) (63)
The genome and the intracellular RNAs of avian myeloblastosis virus (1981) (62)
Trends in oncogenes (1985) (60)
Nucleotide sequence and topography of chicken c-fps. Genesis of a retroviral oncogene encoding a tyrosine-specific protein kinase. (1985) (60)
Homologies among the nucleotide sequences of the genomes of C-type viruses. (1974) (59)
Isolation of messenger RNA for an immunoglobulin kappa chain and enumeration of the genes for the constatn region of kappa chain in the mouse. (1974) (58)
The leader sequence of the subgenomic mRNA's of Rous sarcoma virus is approximately 390 nucleotides (1982) (58)
Deoxyribonucleic Acid Polymerase Associated with Avian Tumor Viruses: Secondary Structure of the Deoxyribonucleic Acid Product (1971) (58)
The low molecular weight RNAs of Rous sarcoma virus. II. The 7 S RNA. (1970) (56)
Virus-specific messenger RNAs in permissive cells infected by avian sarcoma virus. (1979) (55)
Detection and enumeration of transformation-defective strains of avian sarcoma virus with molecular hybridization. (1977) (55)
An agar cell-suspension plaque assay for isolated viral RNA. (1966) (53)
The membrane glycoprotein encoded by the retroviral oncogene v-erb-B is structurally related to tyrosine-specific protein kinases. (1984) (53)
Use of DNA-DNA Annealing to Detect New Virus-Specific DNA Sequences in Chicken Embryo Fibroblasts After Infection by Avian Sarcoma Virus (1974) (53)
Characteristics of virus-specific RNA in avian sarcoma virus-transformed BHK-21 cells and revertants. (1977) (51)
The nucleotide sequence of an untranslated but conserved domain at the 3' end of the avian sarcoma virus genome (1980) (51)
Sustained expression of the human protooncogene MYCN rescues rat embryo cells from senescence. (1988) (51)
A mutation at the major phosphotyrosine in pp60v-src alters oncogenic potential. (1984) (51)
At least 104 nucleotides are transposed from the 5′ terminus of the avian sarcoma virus genome to the 5′ termini of smaller viral mrnas (1978) (50)
Origin and function of avian retrovirus transforming genes. (1980) (50)
Association of pRas and pRaf-1 in a complex correlates with activation of a signal transduction pathway (1993) (50)
Cell-free translation of avian sarcoma virus RNA: Suppression of the gag termination codon does not augment synthesis of the joint gag/pol Product (1978) (50)
Poliovirus replicative intermediate: structural basis of infectivity. (1969) (49)
Presence of DNA in Rous Sarcoma Virus (1970) (49)
Interaction between MYC and MCL1 in the genesis and outcome of non-small-cell lung cancer. (2011) (49)
The low molecular weight RNAs of Rous sarcoma virus. I. The 4 S RNA. (1970) (48)
tRNATrp as primer for RNA-directed DNA polymerase: structural determinants of function. (1979) (47)
Nucleostemin maintains self-renewal of embryonic stem cells and promotes reprogramming of somatic cells to pluripotency (2012) (46)
Synthesis of plus strands of retroviral DNA in cells infected with avian sarcoma virus and mouse mammary tumor virus (1981) (46)
Genome-wide screen for allelic imbalance in a mouse model for neuroblastoma. (2000) (46)
Nucleotide sequence of the 5' noncoding region and part of the gag gene of Rous sarcoma virus (1982) (46)
Nucleotide sequence that binds primer for DNA synthesis to the avian sarcoma virus genome (1976) (45)
Analysis of endogenous avian retrovirus DNA and RNA: viral and cellular determinants of retrovirus gene expression. (1981) (44)
Site-specific mutagenesis of avian erythroblastosis virus: v-erb-A is not required for transformation of fibroblasts. (1983) (43)
The effect of polycations on the interaction of viral RNA with mammalian cells: studies on the infectivity of single- and double-stranded poliovirus RNA. (1968) (42)
Characterization of DNA complementary to nucleotide sequences at the 5'-terminus of the avian sarcoma virus genome. (1977) (41)
Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB. (1988) (41)
The terminal redundancy of the retrovirus genome facilitates chain elongation by reverse transcriptase. (1981) (41)
Reassociation of 4 S and 5 S RNA's with the genome of avian sarcoma virus. (1975) (41)
Nucleotide sequence of v-fps in the PRCII strain of avian sarcoma virus (1984) (40)
Ribonucleic acid directed deoxyribonucleic acid synthesis by the purified deoxyribonucleic acid polymerase of Rous sarcoma virus. Characterization of the enzymatic product. (1972) (40)
myb provides an essential function during Drosophila development. (1996) (40)
The Metastatic Potential and Chemoresistance of Human Pancreatic Cancer Stem Cells (2016) (40)
Characterization of ribonuclease-resistant RNA from poliovirus-infected HeLa cells. (1965) (40)
Amplification of N-myc sequences in primary human neuroblastomas: correlation with advanced disease stage. (1985) (38)
Characterization of DNA complementary to nucleotide sequences adjacent to poly(A) at the 3'-terminus of the avian sarcoma virus genome. (1977) (37)
Persistence and expression of Marek's disease virus DNA in tumour cells and peripheral nerves studied by in situ hybridization. (1981) (36)
Proteins specified by avian erythroblastosis virus: coding region localization and identification of a previously undetected erb-B polypeptide. (1982) (36)
Nucleotide sequence homologies among mouse mammary tumor viruses. (1976) (36)
Induced differentiation of avian myeloblastosis virus-transformed myeloblasts: phenotypic alteration without altered expression of the viral oncogene (1984) (35)
Avian Retroviruses That Cause Carcinoma and Leukemia: Identification of Nucleotide Sequences Associated with Pathogenicity (1980) (35)
Subcellular localization of the v-erb-B protein, the product of a transforming gene of avian erythroblastosis virus. (1984) (34)
Deoxyribonucleic Acid Polymerase(s) of Rous Sarcoma Virus: Effects of Virion-Associated Endonuclease on the Enzymatic Product (1971) (34)
Transformation parameters induced in chick cells by incubation in media of altered NaCl concentration. (1981) (33)
Orientation of the v-erb-B gene product in the plasma membrane (1986) (33)
Steroid receptors: Oncogenes as hormone receptors (1986) (33)
Transduction of c-myb into avian myeloblastosis virus: locating points of recombination within the cellular gene (1983) (33)
The role of RNA molecules in transduction of the proto-oncogene c-fps (1986) (33)
Alternative processing of RNA transcribed from NMYC (1987) (33)
Acute promyelocytic leukemia: from treatment to genetics and back (1999) (32)
SYNTHESIS OF VIRAL RNA IN CELLS INFECTED BY AVIAN SARCOMA VIRUSES (1976) (32)
The DFer gene of Drosophila melanogaster encodes two membrane-associated proteins that can both transform vertebrate cells (1997) (32)
Transformation of murine myelomonocytic cells by myc: point mutations in v-myc contribute synergistically to transforming potential. (1989) (32)
Purification of DNA complementary to the env gene of avian sarcoma virus and analysis of relationships among the env genes of avian leukosis-sarcoma viruses (1977) (32)
Tumor virus ribonucleic acid directed deoxyribonucleic acid synthesis: nucleotide sequence at the 5' terminus of nascent deoxyribonucleic acid. (1974) (31)
Evidence for non-repetitive subunits in the genome of rous sarcoma virus (1974) (31)
MYB and MYC in the cell cycle. (1991) (30)
A dominant mutant allele of the ING4 tumor suppressor found in human cancer cells exacerbates MYC-initiated mouse mammary tumorigenesis. (2010) (30)
Synthesis, structure, and integration of the DNA of RNA tumor viruses. (1979) (30)
Pulmonary diffusing capacity and its subdivisions in polycythemia vera. (1963) (30)
DNA of Rous Sarcoma Virus: Its Nature and Significance (1972) (30)
Mouse mammary tumor virus/v-Ha-ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4. (1997) (29)
The protooncogene MYC can break B cell tolerance. (2005) (29)
Transcription of ribonucleic acid by the ribonucleic acid directed deoxyribonucleic acid polymerase of Rous sarcoma virus and deoxyribonucleic acid polymerase I of Escherichia coli. (1973) (29)
Poliovirus double-stranded RNA: Inactivation by ultraviolet light (1967) (28)
Integration of avian sarcoma virus DNA in chicken cells. (1981) (28)
Dominant male sterility in mice caused by insertion of a transgene. (1991) (28)
Amplified gene for the epidermal growth factor receptor in a human glioblastoma cell line encodes an enzymatically inactive protein (1988) (28)
Methods for the quantitative assessment of nuclear-polyhedrosis virus in soil (1980) (27)
Neoplastic transformation and tumorigenesis by the human protooncogene MYC. (1990) (26)
Premature termination of transcription from the P1 promoter of the mouse c-myc gene. (1991) (26)
Human protein-tyrosine kinase gene HCK: expression and structural analysis of the promoter region. (1992) (26)
Mutants of Rous sarcoma virus with extensive deletions of the viral genome. (1979) (25)
Integration and expression of several molecular forms of Rous sarcoma virus DNA used for transfection of mouse cells (1984) (24)
A comparison of the high molecular weight RNAs of visna virus and Rous sarcoma virus. (1974) (24)
Production of p60c-src by baculovirus expression and immunoaffinity purification. (1991) (24)
Differences between genomes of two strains of mouse mammary tumor virus as shown by partial RNA sequence analysis. (1976) (24)
RNA interference (RNAi) with RNase III-prepared siRNAs. (2004) (23)
Alfred P. Solan prize. Viruses, genes, and cancer. II. Retroviruses and cancer genes (1985) (23)
Localization of the human AHNAK/desmoyokin gene (AHNAK) to chromosome band 11q12 by somatic cell hybrid analysis and fluorescence in situ hybridization. (1995) (22)
Differential effect of actinomycin D on the infectivity of single- and double-stranded poliovirus RNA. (1967) (22)
Identification of virus-specific RNA in cells infected with Rous sarcoma virus. (1971) (22)
Biochemical mechanisms of oncogene activity: proteins encoded by oncogenes. Introduction. (1986) (21)
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts. (1988) (21)
Double-stranded replication form of poliovirus RNA: phenotype of heterozygous molecules. (1972) (21)
Domains of E1A that bind p105Rb, p130, and p300 are required to block nerve growth factor-induced neurite growth in PC12 cells. (1993) (19)
Deoxyribonucleic Acid Polymerases of Rous Sarcoma Virus: Kinetics of Deoxyribonucleic Acid Synthesis and Specificity of the Products (1971) (19)
Deoxyribonucleic Acid Polymerase of Rous Sarcoma Virus: Studies on the Mechanism of Double-Stranded Deoxyribonucleic Acid Synthesis (1971) (19)
Genesis of a virus-transforming gene. (1978) (19)
Expression during Drosophila development of DER, a gene related to erbB-1 and neu: correlations with mutant phenotypes. (1991) (18)
Six amino acids from the retroviral gene gag greatly enhance the transforming potential of the oncogene v-erb-B. (1990) (18)
env Gene of Chicken RNA Tumor Viruses: Extent of Conservation in Cellular and Viral Genomes (1978) (18)
A gene related to the proto-oncogene fps/fes is expressed at diverse times during the life cycle of Drosophila melanogaster (1991) (18)
Function, location, and regulation of the src protein-tyrosine kinase. (1989) (18)
Rearrangements of chicken immunoglobulin genes in lymphoid cells transformed by the avian retroviral oncogene v-rel. (1988) (18)
Proto-oncogenes of Drosophila melanogaster. (1985) (17)
Coordinate regulation of myelomonocytic phenotype by v-myb and v-myc (1986) (17)
Cellular oncogenes (c-erb-A and c-erb-B) located on different chicken chromosomes can be transduced into the same retroviral genome (1984) (17)
DISTRIBUTION AND FUNCTION OF DEFINED REGIONS OF AVIAN TUMOR VIRUS GENOMES IN VIRUSES AND UNINFECTED CELLS (1976) (17)
Evolution of karyotypic abnormalities and C-MYC oncogene amplification in human colonic carcinoma cell lines (1985) (16)
Scientific American molecular oncology (1996) (16)
Neoplastic transformation by E26 leukemia virus is mediated by a single protein containing domains of gag and myb genes (1984) (16)
Detection and characterization of RNA tumor virus-specific DNA in cells. (1975) (16)
A human gene (AHNAK) encoding an unusually large protein with a 1.2-μm polyionic rod structure (1993) (16)
Structure of a replication intermediate in the synthesis of Rous sarcoma virus DNA in vivo (1982) (16)
Endogenous proviruses of random-bred chickens and ring-necked pheasants: analysis with restriction endonucleases. (1981) (15)
DNA intermediates in the replication of retroviruses are structurally (and perhaps functionally) related to transposable elements. (1981) (15)
The genesis of Rous sarcoma virus messenger RNAs. (1981) (15)
Of birds and mice and men: Comments on the use of animal models and molecular hybridization in the search for human tumor viruses (1974) (14)
Characterization of the nucleic acid product of the visna virus RNA dependent DNA polymerase. (1974) (14)
The amino-terminal 14 amino acids of v-src can functionally replace the extracellular and transmembrane domains of v-erbB (1991) (14)
Genomic progression in mouse models for liver tumors. (2005) (14)
Immunological phenotype of lymphomas induced by avian leukosis viruses (1983) (14)
Diverse expression of dsrc29A, a gene related to src, during the life cycle of Drosophila melanogaster. (1990) (13)
Identification and characterization of dimeric and trimeric circular forms of avian sarcoma virus-specific DNA. (1980) (13)
RNA complementary to the genome of RNA tumor viruses in virions and virus-producing cells (1976) (13)
Transcription of DNA from the 70 S RNA of Rous Sarcoma Virus II . Structure of a 4 S RNA Primer (13)
Mercuric chloride activates the Src-family protein tyrosine kinase, Hck in myelomonocytic cells. (2000) (12)
Convenient non-chromatographic assays for the microbial deconjugation and 7alpha-OH bioconversion of taurocholate. (1975) (12)
13 Oncogenes and Clinical Cancer (1989) (12)
Effect of medium of lowered NaCl concentration on virus release and protein synthesis in cells infected with reticuloendotheliosis virus (1976) (12)
Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma (2015) (12)
β PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells (1995) (12)
A new transgenic mouse line for tetracycline inducible transgene expression in mature melanocytes and the melanocyte stem cells using the Dopachrome tautomerase promoter (2010) (12)
Interaction of psoralen derivatives with the RNA genome of Rous sarcoma virus. (1981) (12)
Monocytes promote liver carcinogenesis in an oncogene-specific manner. (2016) (12)
Retroviruses and oncogenes II (1990) (11)
Redefining the Expression and Function of the Inhibitor of Differentiation 1 in Mammary Gland Development (2010) (11)
Identification of platelet membrane proteins that interact with amino-terminal peptides of pp60c-src. (1991) (11)
A temperature-sensitive phenotype of avian myeloblastosis virus: determinants that influence the production of viral mRNAs (1990) (11)
The presence and expression of RNA tumor virus genes in normal and infected cells: detection by molecular hybridization. (1973) (10)
Transformation of early erythroid precursor cells (BFU-E) by a recombinant murine retrovirus containing v-erb-B. (1990) (10)
The Discovery of Proto‐oncogenes (1996) (9)
Biological and Physicochemical Aspects of Poliovirus-Induced Double-Stranded RNA (1967) (8)
Organization of endogenous and exogenous viral and linked nonviral sequences. (1980) (8)
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene ( c-mnc ) in malignant neuroendocrine cells from a human colon carcinoma ( double minute chromosomes / chromosome aberrations / retroviruses / tumorigenesis ) (8)
Erratum: The Classic: Integration of Deoxyribonucleic Acid Specific for Rous Sarcoma Virus after Infection of Permissive and Nonpermissive Hosts (1973) (8)
Dispersed chromosomal localization of the proto-oncogenes transduced into the genome of Mill Hill 2 or E26 leukemia virus (1986) (8)
Cell-free translation of purified avian sarcoma virus src mRNA. (1981) (7)
Viruses, genes, and cancer. (1989) (7)
The forms of tRNATrp found in avian sarcoma virus and uninfected chicken cells have structural identity but functional distinctions. (1980) (7)
Genes and Cancer (1985) (7)
Proto-oncogenes: Clues to the puzzle of purpose (1985) (7)
Proto-oncogenes and plasticity in cell signaling. (1994) (7)
Detection of nucleotide sequences associated with transformation by avian sarcoma viruses. (1976) (7)
Retroviruses and Oncogenes II (Nobel Lecture) (1990) (7)
Farnesyl transferase inhibitors induce extended remissions in transgenic mice with mature B cell lymphomas (2008) (6)
The molecular biology of RNA tumor viruses: a physician's guide. (1980) (6)
Repair of lesions which cause premature termination of transcription in chicken embryo cells irradiated with ultraviolet light. (1981) (6)
Molecular cloning of the PRCII sarcoma viral genome and the chicken proto-oncogene c-fps. (1985) (6)
Mouse mammary tumor virusyv-Ha-ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4 (allelotypeyloss of heterozygosityytumor suppressor geneytransgenic miceyexperimental breast neoplasms) (1997) (6)
TRANSFER RNAs OF ROUS SARCOMA VIRUS AND THE INITIATION OF DNA SYNTHESIS BY VIRAL REVERSE TRANSCRIPTASE (1974) (5)
Synthesis of RNA in normal and Rous sarcoma virus-infected cells: effect of bromodeoxyuridine. (1970) (5)
Transformation-defective mutant of avian myeloblastosis virus that is temperature sensitive for production of transforming protein p45v-myb (1985) (5)
THE ORIGIN AND STRUCTURE OF ENDOGENOUS RETROVIRAL DNA (1980) (4)
A 3' truncation of myc caused by chromosomal translocation in a human T-cell leukemia is tumorigenic when tested in established rat fibroblasts. (1991) (4)
Characteristics of the Transcription of RNA by the DNA Polymerase of Rous Sarcoma Virus (1973) (4)
Identification of a tRNA nucleotidyltransferase and its substrates in virions of avian RNA tumor viruses. (1974) (4)
Beta PDGF receptor mutants defective for mitogenesis promote neurite outgrowth in PC12 cells. (1995) (4)
The Classic: Integration of Deoxyribonucleic Acid Specific for Rous Sarcoma Virus after Infection of Permissive and Nonpermissive Hosts (2008) (4)
Viral oncogenes (1985) (4)
Nobel Lecture. Retroviruses and oncogenes II. (1990) (4)
The replication of subgroup E avian retroviruses is blocked at or before viral DNA synthesis in restrictive chicken cells. (1979) (4)
Transcription of the Rous sarcoma virus genome in vitro and in vivo. (1975) (3)
Amplification of Proto-oncogenes in Tumorigenesis (1986) (3)
Viruses, Genes, and Cancer: a Lineage of Discovery (1995) (3)
Premature termination of transcription from the P 1 promoter of the mouse c-myc gene ( regulation / protooncogenes ) (3)
Mary Lasker and her prizes: an appreciation. (2005) (3)
Exploring carcinogenesis with retroviral and cellular oncogenes. (1985) (2)
Genes and cancer : proceedings of a CETUS-UCLA Symposium held in Steamboat Springs, Colorado, March 11-17, 1984 (1984) (2)
Synthesis ofPlusStrands ofRetroviral DNA inCells Infected withAvianSarcoma Virus andMouseMammaryTumor Virust (1981) (2)
The Provirus of Rous Sarcoma Virus: Synthesis, Integration and Transcription (1975) (2)
Misguided cells: the genesis of human cancer. (1994) (2)
Molecular and Cellular Pathobiology Activated Notch 1 Induces Lung Adenomas in Mice and Cooperates with Myc in the Generation of Lung Adenocarcinoma (2011) (1)
Nucleotide sequence of the v-myc oncogene of avian retrovirus MC 29 ( leukemia / carcinoma / myelocytomatosis / tumor virus / DNA-binding protein ) (2003) (1)
The molecular genetics of cancer: 1988. (1988) (1)
Synthesis and Integration of Rous Sarcoma Virus Proviral DNA in Duck Embryo Fibroblast Cells (1975) (1)
Cancer Therapy: Diamond‐Lipid Hybrids Enhance Chemotherapeutic Tolerance and Mediate Tumor Regression (Adv. Mater. 26/2013) (2013) (1)
Effects ofTranslocations on Transcription fromPVT (1990) (1)
Oncogenes: Tricks with tyrosine kinases (1986) (1)
MYCN and Neuroblastoma in Transgenic Mice (1999) (1)
Abstract 310: Oncogene-specific regulation of immune responses during tumorigenesis (2012) (1)
Viral oncogenes: curiosity or paradigm? (1982) (1)
Molecular models for glial neoplasia: Progress in an ASTRO research fellowship (1991) (0)
Retroviruses. (2018) (0)
Appendix E: Preparation and Use of Recombinant Molecules Involving Animal Virus Genomes (1975) (0)
Persistent DNA DamageInhibits S-Phase andG2 Progression, andResults inApoptosis (1997) (0)
Transduction ofc-mybinto AvianMyeloblastosis Virus: Locating Points ofRecombination within theCellular Gene (1983) (0)
Inhibition of RNA-Dependent DNA Polym by Thiosemicarbazones and Several Catior (2016) (0)
The Progession to Tumourigenes is Following Transformation of Murine Myelomonocytic Cell by V-Myc (1988) (0)
Expression of Oncogenes in Human Leukemias 1 (2006) (0)
THE GENESIS OF AVIAN RETROVIRUS ONCOGENES (1980) (0)
Abstract B17: Sox9 mediates Notch pathway-induced epithelial-mesenchymal transition (EMT) in lung adenocarcinoma. (2014) (0)
Subcellular location of an abundant substrate (p36) for tyrosine-specific protein kinases (1983) (0)
(double minute chromosomes/chromosome aberrations/retroviruses/ (2016) (0)
Structure oftheProtein EncodedbytheChicken Proto-Oncogene c-myb (1986) (0)
lnteractiqn of Psoralen Derivatives with the RNA Genome of Rous Sarcoma Virus (2003) (0)
Radiation carcinogenesis in transgenic mouse models: Progress of an A.S.T.R.O. Research fellowship (1990) (0)
The pathobiology of proto-oncogenes. (1986) (0)
Subject Index, Vol. 70, 1995 (1995) (0)
Synthesis and Integration of Virus-specific DNA in Cells Infected by RNA Tumor Viruses (1978) (0)
Structures of unintegrated and integrated forms of the deoxyribonucleic acid of ribonucleic acid tumour viruses. (1979) (0)
Transforming genes in chronic myelogenous leukemia ( oncogenes / tumor progression / transfection / RAS ) (0)
Functional Analysis oftheAUG-andCUG-Initiated Formsofthec-MycProtein (1994) (0)
Neoplastic transformation and tumorigenesis by the human (2016) (0)
Correct Integration of Rettwiral DNA In Vitro - (2003) (0)
Letter: Evidence for non-repetitive subunits in the genome of Rous sarcoma virus. (1974) (0)
Methods in Molecular Biology, Vol. 270 : Parasite Genomic Protocols edited by S.E. Melville : book review (2005) (0)
Abstract PR1: Oncogenic driver mutations shape the nature of immune responses in tumors. (2013) (0)
Transcription ofDNA fromthe70SRNA ofRousSarcoma Virus II. Structure ofa4SRNAPrimer (1974) (0)
Abstract 1149: The role of the novel Notch1-Sox9 signaling axis in NSCLC progression and EMT (2014) (0)
O-14 A reversible two-step model ofMDS/preleukemia: Transgenic mice expressing inducible BCL2 and mutant NRAS (2005) (0)
Abstract P1-04-01: Loss of Notch4 reduces mammary tumorigenesis by MYC and activated KRAS (2012) (0)
The Molecular Genetics of Avian Erythroblastosis Virus (1983) (0)
DmFer: Fer protein-tyrosine kinase (D. melanogaster) (1995) (0)
Molecular and Cellular Pathobiology Interaction between MYC and MCL 1 in the Genesis and Outcome of Non – Small-Cell Lung Cancer (2011) (0)
Abstract IA25: MYC as therapeutic target (2015) (0)
Hospital merger leaves clinical science intact (1999) (0)
A method for effective RNA interference in mammalian cells (2003) (0)
8 – Molecular Biology of Oncogenes (1991) (0)

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