Jack Tuszyński
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Polish oncologist and physicist
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Jack Tuszyński's Degrees
- PhD Physics University of Warsaw
- Doctorate Medicine Medical University of Warsaw
Why Is Jack Tuszyński Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jack Tuszyński is a Polish professor of oncology and physicist. Biography Tuszyński graduated with a master's degree in physics from the University of Poznan in 1980 and obtained his PhD in condensed matter physics three years later from the University of Calgary. He became a postdoctoral fellow at the chemistry department the same year. From 1983 to 1988 he worked at the Department of Physics of the Memorial University of Newfoundland, then worked in the same department at the University of Alberta for two years. From 1990 to 1993 he was promoted to associate, then full professor, and as of 2005 became Allard Chair of the Cross Cancer Institute. He also served in a Division of Experimental Oncology and is an editor of such journals as the Journal of Biological Physics, Research Letters in Physics and many others which brought him an h-index of 32 as of 2014.
Jack Tuszyński's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Software for molecular docking: a review (2017) (754)
- Quantum computation in brain microtubules: decoherence and biological feasibility. (2000) (372)
- Three-dimensional molecular theory of solvation coupled with molecular dynamics in Amber. (2010) (212)
- A simple cellular automaton model for influenza A viral infections. (2004) (193)
- Ferroelectric behavior in microtubule dipole lattices: Implications for information processing, signaling and assembly/disassembly* (1995) (186)
- Conduction pathways in microtubules, biological quantum computation, and consciousness. (2002) (169)
- The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease (2012) (158)
- Cytoskeletal Signaling: Is Memory Encoded in Microtubule Lattices by CaMKII Phosphorylation? (2012) (148)
- Ionic wave propagation along actin filaments. (2004) (131)
- Analysis of the migration behaviour of single microtubules in electric fields. (2002) (129)
- Molecular and Cellular Biophysics (2007) (126)
- Anisotropic elastic properties of microtubules (2005) (125)
- Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor Design (2020) (117)
- A biopolymer transistor: electrical amplification by microtubules. (2006) (116)
- Discovery and characterization of the laulimalide-microtubule binding mode by mass shift perturbation mapping. (2010) (112)
- Molecular dynamics simulations of tubulin structure and calculations of electrostatic properties of microtubules (2005) (108)
- A unique mode of microtubule stabilization induced by peloruside A. (2008) (101)
- Molecular signaling network complexity is correlated with cancer patient survivability (2012) (97)
- The Uniqueness of Albumin as a Carrier in Nanodrug Delivery. (2021) (96)
- Emission of mitochondrial biophotons and their effect on electrical activity of membrane via microtubules. (2010) (93)
- Systematic Identification and Evolutionary Analysis of Catalytically Versatile Cytochrome P450 Monooxygenase Families Enriched in Model Basidiomycete Fungi (2014) (90)
- Automatic prediction of tumour malignancy in breast cancer with fractal dimension (2016) (89)
- Cancer as a dynamical phase transition (2011) (88)
- Self-organization and entropy reduction in a living cell (2013) (87)
- Dielectric polarization, electrical conduction, information processing and quantum computation in microtubules. Are they plausible? (1998) (87)
- Possible existence of optical communication channels in the brain (2016) (85)
- Dynamics of RASSF1A/MOAP-1 Association with Death Receptors (2008) (85)
- Analytic theories of allometric scaling (2011) (77)
- The Roles of β-Tubulin Mutations and Isotype Expression in Acquired Drug Resistance (2007) (76)
- Small Molecule Inhibitors of ERCC1-XPF Protein-Protein Interaction Synergize Alkylating Agents in Cancer Cells (2013) (76)
- The evolution of the structure of tubulin and its potential consequences for the role and function of microtubules in cells and embryos. (2006) (76)
- Synthesis and evaluation of 1,5-diaryl-substituted tetrazoles as novel selective cyclooxygenase-2 (COX-2) inhibitors. (2011) (75)
- The emerging physics of consciousness (2006) (74)
- Neural cytoskeleton capabilities for learning and memory (2009) (73)
- The feasibility of coherent energy transfer in microtubules (2014) (71)
- Elastic vibrations in seamless microtubules (2005) (68)
- Computational Predictions of Volatile Anesthetic Interactions with the Microtubule Cytoskeleton: Implications for Side Effects of General Anesthesia (2012) (65)
- DIPOLE INTERACTIONS IN AXONAL MICROTUBULES AS A MECHANISM OF SIGNAL PROPAGATION (1997) (65)
- An Overview of Molecular Modeling for Drug Discovery with Specific Illustrative Examples of Applications (2019) (63)
- Estimation of the number of biophotons involved in the visual perception of a single-object image: biophoton intensity can be considerably higher inside cells than outside. (2010) (62)
- Search for Magnetic Monopoles with the MoEDAL Forward Trapping Detector in 13 TeV Proton-Proton Collisions at the LHC. (2016) (62)
- Exact solutions of the multidimensional classical φ6‐field equations obtained by symmetry reduction (1987) (62)
- A nonlinear model of ionic wave propagation along microtubules (2009) (61)
- Cancer proliferation and therapy: the Warburg effect and quantum metabolism (2010) (60)
- An Overview of Sub-Cellular Mechanisms Involved in the Action of TTFields (2016) (60)
- Virtual Screening and Biological Evaluation of Inhibitors Targeting the XPA-ERCC1 Interaction (2012) (59)
- Identification and Characterization of an Intermediate Taxol Binding Site Within Microtubule Nanopores and a Mechanism for Tubulin Isotype Binding Selectivity (2009) (57)
- Modeling the energetic cost of cancer as a result of altered energy metabolism: implications for cachexia (2015) (57)
- Anesthetics act in quantum channels in brain microtubules to prevent consciousness. (2015) (56)
- Ensemble-based virtual screening reveals dual-inhibitors for the p53-MDM2/MDMX interactions. (2010) (55)
- Search for magnetic monopoles with the MoEDAL prototype trapping detector in 8 TeV proton-proton collisions at the LHC (2016) (55)
- Transitions in microtubule C-termini conformations as a possible dendritic signaling phenomenon (2005) (55)
- Introduction to Molecular Biophysics (2003) (54)
- Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s (2016) (53)
- DNA polymerase beta (pol β) inhibitors: a comprehensive overview. (2012) (50)
- Quantum effects in the understanding of consciousness. (2014) (50)
- Magnetic Monopole Search with the Full MoEDAL Trapping Detector in 13 TeV pp Collisions Interpreted in Photon-Fusion and Drell-Yan Production. (2019) (50)
- Toward precision medicine of breast cancer (2016) (49)
- A Refined Model of the HCV NS5A Protein Bound to Daclatasvir Explains Drug-Resistant Mutations and Activity against Divergent Genotypes (2015) (47)
- Comparative modelling of human β tubulin isotypes and implications for drug binding (2006) (47)
- Possible role of electrodynamic interactions in long-distance biomolecular recognition. (2014) (47)
- Advances in structural biology (1991) (47)
- Conformational analysis of the carboxy-terminal tails of human beta-tubulin isotypes. (2008) (47)
- A review of the ferroelectric model of microtubules (1999) (46)
- Anesthetic Alterations of Collective Terahertz Oscillations in Tubulin Correlate with Clinical Potency: Implications for Anesthetic Action and Post-Operative Cognitive Dysfunction (2017) (46)
- A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity. (2014) (45)
- Fractal pharmacokinetics of the drug mibefradil in the liver. (2002) (43)
- Tubulin response to intense nanosecond-scale electric field in molecular dynamics simulation (2019) (42)
- Structural mass spectrometry of the alpha beta-tubulin dimer supports a revised model of microtubule assembly. (2009) (41)
- A strategy to identify housekeeping genes suitable for analysis in breast cancer diseases (2016) (41)
- Analysis of the strength of interfacial hydrogen bonds between tubulin dimers using quantum theory of atoms in molecules. (2014) (41)
- Relationship between the nonlinear ferroelectric and liquid crystal models for microtubules. (2003) (41)
- Models of spatial and orientational self-organization of microtubules under the influence of gravitational fields. (2003) (40)
- Plausibility of quantum coherent states in biological systems (2010) (40)
- Relaxed complex scheme suggests novel inhibitors for the lyase activity of DNA polymerase beta. (2011) (40)
- Tubulin: Structure, Functions and Roles in Disease (2019) (40)
- Characterization of an inhibitory dynamic pharmacophore for the ERCC1-XPA interaction using a combined molecular dynamics and virtual screening approach. (2009) (39)
- DNA repair inhibitors: the next major step to improve cancer therapy. (2012) (38)
- Effects of Temperature on the p53-DNA Binding Interactions and Their Dynamical Behavior: Comparing the Wild Type to the R248Q Mutant (2011) (38)
- Microtubule ionic conduction and its implications for higher cognitive functions. (2010) (37)
- Boolean gates on actin filaments (2015) (37)
- Biological wires, communication systems, and implications for disease (2015) (37)
- Discovery of Small Molecule Inhibitors that Interact with γ‐Tubulin (2012) (36)
- Modeling the structure of the frameshift-stimulatory pseudoknot in SARS-CoV-2 reveals multiple possible conformers (2020) (35)
- Quantitative analysis of the effect of tubulin isotype expression on sensitivity of cancer cell lines to a set of novel colchicine derivatives (2010) (35)
- Model of ionic currents through microtubule nanopores and the lumen. (2009) (35)
- Coherent structures in strongly interacting many-body systems. I. Derivation of dynamics (1989) (35)
- Molecular dynamics modeling of tubulin C‐terminal tail interactions with the microtubule surface (2011) (34)
- Implications of quantum metabolism and natural selection for the origin of cancer cells and tumor progression. (2012) (34)
- Neuropsychiatric Illness: A Case for Impaired Neuroplasticity and Possible Quantum Processing Derailment in Microtubules (2009) (34)
- Entropic Fragment‐Based Approach to Aptamer Design (2011) (34)
- Quantum metabolism explains the allometric scaling of metabolic rates (2010) (33)
- Exact results in the three-dimensional Landau-Ginzburg model of magnetic inhomogeneities in uniaxial ferromagnets: I. Continuous transitions (1988) (33)
- Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates (2016) (32)
- New design of nucleotide excision repair (NER) inhibitors for combination cancer therapy. (2016) (32)
- Chemotherapy Drugs Form Ion Pores in Membranes Due to Physical Interactions with Lipids (2012) (32)
- Thermodynamic measures of cancer: Gibbs free energy and entropy of protein–protein interactions (2016) (31)
- Coherent structures in strongly interacting many-body systems. II. Classical solutions and quantum fluctuations (1989) (31)
- Investigation of the Josephin Domain Protein-Protein Interaction by Molecular Dynamics (2014) (30)
- Conformational fluctuations of the AXH monomer of Ataxin‐1 (2016) (30)
- Information processing mechanisms in microtubules at physiological temperature: Model predictions for experimental tests (2009) (30)
- Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies (2018) (29)
- Microtubule assembly of isotypically purified tubulin and its mixtures. (2008) (29)
- The Dendritic Cytoskeleton as a Computational Device: An Hypothesis (2006) (29)
- Stochastic and Deterministic Models of Cellular p53 Regulation (2013) (28)
- Detailed Computational Study of the Active Site of the Hepatitis C Viral RNA Polymerase to Aid Novel Drug Design (2013) (28)
- Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development (2016) (28)
- "Memory bytes" - molecular match for CaMKII phosphorylation encoding of microtubule lattices. (2010) (28)
- Design principles for cancer therapy guided by changes in complexity of protein-protein interaction networks (2015) (28)
- A critical assessment of the information processing capabilities of neuronal microtubules using coherent excitations (2010) (28)
- Microtubules as Sub-Cellular Memristors (2020) (27)
- Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma (2017) (27)
- Ion Channel and Neurotransmitter Modulators as Electroceutical Approaches to the Control of Cancer (2017) (27)
- The Unique Binding Mode of Laulimalide to Two Tubulin Protofilaments (2015) (27)
- The Path Ahead (2006) (27)
- Quantum states in proteins and protein assemblies: The essence of life? (2004) (27)
- Building a 3D Virtual Liver: Methods for Simulating Blood Flow and Hepatic Clearance on 3D Structures (2016) (26)
- Regulation of Channel Function Due To Coupling With a Lipid Bilayer (2012) (26)
- Response to Alternating Electric Fields of Tubulin Dimers and Microtubule Ensembles in Electrolytic Solutions (2017) (26)
- Keeping time: could quantum beating in microtubules be the basis for the neural synchrony related to consciousness? (2014) (26)
- Mössbauer effect as a possible tool in detecting nonlinear excitations in microtubules (1998) (26)
- Quantitative analysis of the frequency spectrum of the radiation emitted by cytochrome oxidase enzymes. (2001) (26)
- Fractal Michaelis-Menten Kinetics Under Steady State Conditions: Application to Mibefradil (2006) (25)
- Analysis of the three-dimensional time-dependent Landau−Ginzburg equation and its solutions (1989) (25)
- A Computational Strategy to Select Optimized Protein Targets for Drug Development toward the Control of Cancer Diseases (2015) (25)
- Determination of Noscapine’s Localization and Interaction with the Tubulin‐α/β Heterodimer (2011) (24)
- Results of Molecular Dynamics Computations of the Structural and Electrostatic Properties of Tubulin and Their Consequences for Microtubules (2004) (24)
- Review and application of group theory to molecular systems biology (2011) (24)
- Molecular Dynamics Simulations Indicate the SARS-CoV-2 Mpro Is Not a Viable Target for Small-Molecule Inhibitors Design (2020) (24)
- SEARCH FOR QUANTUM AND CLASSICAL MODES OF INFORMATION PROCESSING IN MICROTUBULES: IMPLICATIONS FOR “THE LIVING STATE” (2003) (23)
- Structure Based Modeling of Small Molecules Binding to the TLR7 by Atomistic Level Simulations (2015) (23)
- Detailed Per-residue Energetic Analysis Explains the Driving Force for Microtubule Disassembly (2015) (23)
- A physiologically-based flow network model for hepatic drug elimination I: regular lattice lobule model (2011) (23)
- Effect of Calcium on Electrical Energy Transfer by Microtubules (2008) (23)
- Mechanisms of exciton energy transfer in Scheibe aggregates. (1999) (23)
- Correction: The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease (2012) (23)
- Elucidating the Mechanism of Action of the Clinically Approved Taxanes: A Comprehensive Comparison of Local and Allosteric Effects (2015) (22)
- Homology modeling of tubulin: influence predictions for microtubule’s biophysical properties (2006) (22)
- Characterization of the AXH domain of Ataxin‐1 using enhanced sampling and functional mode analysis (2016) (22)
- Biomedical Applications for Introductory Physics (2001) (22)
- Modeling the Yew Tree Tubulin and a Comparison of its Interaction with Paclitaxel to Human Tubulin (2012) (22)
- Selected physical issues in the structure and function of microtubules. (1997) (22)
- Tubulin's response to external electric fields by molecular dynamics simulations (2018) (21)
- Inhibitory Activity of Iron Chelators ATA and DFO on MCF-7 Breast Cancer Cells and Phosphatases PTP1B and SHP2. (2017) (21)
- Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents (2017) (21)
- The enigma of microtubules and their self-organizing behavior in the cytoskeleton. (1997) (21)
- Electrodynamic Signaling by the Dendritic Cytoskeleton: Toward an Intracellular Information Processing Model (2005) (21)
- Models of Assembly and Disassembly of Individual Microtubules: Stochastic and Averaged Equations (1999) (21)
- Models of the Collective Behavior of Proteins in Cells: Tubulin, Actin and Motor Proteins (2003) (21)
- Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives (2018) (21)
- On the possible quantum role of serotonin in consciousness. (2015) (20)
- First Search for Dyons with the Full MoEDAL Trapping Detector in 13 TeV pp Collisions. (2020) (20)
- Novel Colchicine Derivatives and their Anti-cancer Activity. (2017) (20)
- Antitumor Activity of Lankacidin Group Antibiotics Is Due to Microtubule Stabilization via a Paclitaxel-like Mechanism. (2016) (20)
- EDEn–Electroceutical Design Environment: Ion Channel Tissue Expression Database with Small Molecule Modulators (2018) (20)
- Estimating hydrogen bond energies: comparison of methods (2014) (20)
- Chicoric acid binds to two sites and decreases the activity of the YopH bacterial virulence factor (2016) (20)
- Identification of tubulin drug binding sites and prediction of relative differences in binding affinities to tubulin isotypes using digital signal processing. (2008) (20)
- Linoleic acid: Is this the key that unlocks the quantum brain? Insights linking broken symmetries in molecular biology, mood disorders and personalistic emergentism (2017) (19)
- Elastic properties of Rb4LiH3(SO4)4 and K4LiH3(SO4)4 (1991) (18)
- Continuous model for microtubule dynamics with catastrophe, rescue, and nucleation processes. (2008) (18)
- Bio-Ferroelectricity at the Nanoscale (2008) (18)
- The Role of Structural Polymorphism in Driving the Mechanical Performance of the Alzheimer's Beta Amyloid Fibrils (2019) (18)
- Biophysical Insights into Cancer Transformation and Treatment (2013) (18)
- Synthesis, Antiproliferative Activity and Molecular Docking Studies of Novel Doubly Modified Colchicine Amides and Sulfonamides as Anticancer Agents (2020) (18)
- Insights into the Effect of the G245S Single Point Mutation on the Structure of p53 and the Binding of the Protein to DNA (2017) (18)
- Analysis of the binding mode of laulimalide to microtubules: Establishing a laulimalide–tubulin pharmacophore (2016) (18)
- A Review of the Recent Development in the Synthesis and Biological Evaluations of Pyrazole Derivatives (2022) (17)
- Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2). (2012) (17)
- A new antiproliferative noscapine analogue: chemical synthesis and biological evaluation (2016) (17)
- Personalized anticancer therapy selection using molecular landscape topology and thermodynamics (2016) (17)
- A computationally designed DNA aptamer template with specific binding to phosphatidylserine. (2013) (17)
- An integrated multidisciplinary model describing initiation of cancer and the Warburg hypothesis (2013) (17)
- The use of compressive sensing and peak detection in the reconstruction of microtubules length time series in the process of dynamic instability (2015) (17)
- Modeling the Colchicum autumnale Tubulin and a Comparison of Its Interaction with Colchicine to Human Tubulin (2017) (17)
- A simple method for finding a protein’s ligand-binding pockets (2014) (17)
- The Physical Mechanism for Retinal Discrete Dark Noise: Thermal Activation or Cellular Ultraweak Photon Emission? (2016) (16)
- Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents (2018) (16)
- Derivatives of thiocolchicine and its applications to CEM cells treatment using 19F magnetic resonance ex vivo. (2010) (16)
- All Wired Up: An Exploration of the Electrical Properties of Microtubules and Tubulin. (2020) (16)
- On the ferroelastic phase transition of LiNH4SO4: a Brillouin scattering study and theoretical modelling (1989) (16)
- Analytical expressions for energies, degeneracies and critical temperatures of the 2D square and 3D cubic Ising models (2005) (16)
- A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models (2016) (15)
- Integration of intracellular signaling: Biological analogues of wires, processors and memories organized by a centrosome 3D reference system (2018) (15)
- Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents. (2020) (15)
- On the ferroelastic phase transition in LiKSO4: Brillouin scattering studies from 140 to 300 K and Landau theory modelling (1989) (15)
- Ionic Waves Propagation Along the Dendritic Cytoskeleton as a Signaling Mechanism (2006) (15)
- Computer assisted design of second-generation colchicine derivatives (2010) (15)
- GLUT1 and TUBB4 in Glioblastoma Could be Efficacious Targets (2019) (15)
- Exact eigenvalues of the Ising Hamiltonian in one-, two- and three-dimensions in the absence of a magnetic field (2001) (15)
- Rayleigh instability of the inverted one-cell amphibian embryo (2008) (15)
- Are there optical communication channels in the brain? (2017) (15)
- Explicitly solvated ligand contribution to continuum solvation models for binding free energies: selectivity of theophylline binding to an RNA aptamer. (2010) (15)
- Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β-Tubulin Isoforms (2008) (15)
- Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives. (2016) (14)
- Similarity-based virtual screening for microtubule stabilizers reveals novel antimitotic scaffold. (2013) (14)
- Non-linearity and the emergence of coherence in strongly interacting many-body systems near a critical point (1989) (14)
- Symmetry reduction for the three-dimensional Landau-Ginzburg equation☆ (1988) (14)
- Electrodynamics of microtubular motors: the building blocks of a new model. (1996) (14)
- Investigation of the Electrical Properties of Microtubule Ensembles under Cell-Like Conditions (2020) (14)
- Computer-aided design of magnetic molecularly imprinted polymer nanoparticles for solid-phase extraction and determination of levetiracetam in human plasma (2018) (14)
- Theory and Mathematical Methods in Bioinformatics (2008) (14)
- Emission of Biophotons and Neural Activity of the Brain (2010) (14)
- Effect of CH-35, a novel anti-tumor colchicine analogue, on breast cancer cells overexpressing the βIII isotype of tubulin (2016) (14)
- Regulation of channel function due to physical energetic coupling with a lipid bilayer. (2014) (14)
- Complex movements of motor protein relay helices during the power stroke. (2006) (14)
- Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes. (2018) (14)
- Torsional elastic deformations of microtubules within continuous sheet model (2010) (14)
- Novel mutations involving βI-, βIIA-, or βIVB-tubulin isotypes with functional resemblance to βIII-tubulin in breast cancer (2017) (14)
- An Accurate Method for Prediction of Protein-Ligand Binding Site on Protein Surface Using SVM and Statistical Depth Function (2013) (14)
- A computational model for overcoming drug resistance using selective dual-inhibitors for aurora kinase A and its T217D variant. (2013) (13)
- Theorizing how the brain encodes consciousness based on negentropic entanglement. (2019) (13)
- Determination of the optimal tubulin isotype target as a method for the development of individualized cancer chemotherapy (2013) (13)
- Designing and Testing of Novel Taxanes to Probe the Highly Complex Mechanisms by Which Taxanes Bind to Microtubules and Cause Cytotoxicity to Cancer Cells (2015) (13)
- Optimization of combination chemotherapy based on the calculation of network entropy for protein-protein interactions in breast cancer cell lines (2015) (13)
- The need for a physical basis of cognitive process: comment on "Consciousness in the universe. A review of the 'Orch OR' theory" by Hameroff and Penrose. (2014) (13)
- Comments on phase-front propagation in ferroelectrics (1994) (13)
- A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models (2013) (13)
- Thermodynamic and kinetic stability of the Josephin Domain closed arrangement: evidences from replica exchange molecular dynamics (2017) (13)
- Near death experiences: a multidisciplinary hypothesis (2013) (13)
- Targeting DNA Repair in Tumor Cells via Inhibition of ERCC1-XPF. (2019) (12)
- Bridging the Gap between the Technological Singularity and Medicine: Highlighting a Course on Technology and the Future of Medicine (2013) (12)
- Microtubules: strange polymers inside the cell. (1999) (12)
- Computer‐aided drug design of small molecule inhibitors of the ERCC1‐XPF protein–protein interaction (2019) (12)
- In silico studies and fluorescence binding assays of potential anti-prion compounds reveal an important binding site for prion inhibition from PrP(C) to PrP(Sc). (2015) (12)
- Destabilizing the AXH Tetramer by Mutations: Mechanisms and Potential Antiaggregation Strategies. (2018) (12)
- Activation of Hydrogen Peroxide to Peroxytetradecanoic Acid Is Responsible for Potent Inhibition of Protein Tyrosine Phosphatase CD45 (2012) (12)
- Algebraic and topological indices of molecular pathway networks in human cancers. (2014) (12)
- Fröhlich's condensation in a biological membrane viewed as a Davydov soliton (1989) (12)
- Probabilistic analysis of the frequencies of amino acid pairs within characterized protein sequences (2006) (12)
- Peloruside, Laulimalide, and Noscapine Interactions with Beta-Tubulin (2012) (12)
- α-Synuclein dimer structures found from computational simulations. (2015) (12)
- New classes of exact solutions of the 6 model in 3+1 dimensions (1987) (12)
- Vibrational dynamics of bio- and nano-filaments in viscous solution subjected to ultrasound: implications for microtubules (2011) (12)
- Geometrical comparison of two protein structures using Wigner‐D functions (2013) (11)
- Structural and Evolutionary Analysis Indicate that the SARS-CoV-2 Mpro is an Inconvenient Target for Small-Molecule Inhibitors Design (2020) (11)
- The theory of spin correlated crystal fields (1984) (11)
- Non-linear aspects of the Landau-Ginzburg model with applications to new high temperature superconductors (1989) (11)
- The ferroelastic phase transition in (NH4)4LiH3(SO4)4: Brillouin scattering studies and Landau theory modeling (1993) (11)
- Computational Characterization of Small Molecules Binding to the Human XPF Active Site and Virtual Screening to Identify Potential New DNA Repair Inhibitors Targeting the ERCC1-XPF Endonuclease (2018) (11)
- Computational Design and Biological Testing of Highly Cytotoxic Colchicine Ring A Modifications (2010) (11)
- Asymptotic time dependence in the fractal pharmacokinetics of a two-compartment model. (2005) (11)
- Charge-based interactions of antimicrobial peptides and general drugs with lipid bilayers. (2019) (11)
- Nonlinear Field Theories and Non‐Gaussian Fluctuations for Near‐Critical Many‐Body Systems (1994) (11)
- Inactivation of Protein Tyrosine Phosphatases by Peracids Correlates with the Hydrocarbon Chain Length (2015) (11)
- Emergence of power laws in the pharmacokinetics of paclitaxel due to competing saturable processes. (2008) (11)
- Biophysical Implications of the Peyrard-BishopDauxois Model of DNA Dynamics (2004) (11)
- The Cytoskeleton as a Nanoscale Information Processor: Electrical Properties and an Actin-Microtubule Network Model (2009) (10)
- Effects of distance dependence of exciton hopping on the Davydov soliton (1995) (10)
- Mathematical and computational modeling in biology at multiple scales (2014) (10)
- Novel Allosteric Pathway of Eg5 Regulation Identified through Multivariate Statistical Analysis of Hydrogen-Exchange Mass Spectrometry (HX-MS) Ligand Screening Data* (2017) (10)
- Optomechanical proposal for monitoring microtubule mechanical vibrations. (2017) (10)
- A mean field Ising model for cortical rotation in amphibian one-cell stage embryos (2012) (10)
- Signaling Complexity Measured by Shannon Entropy and Its Application in Personalized Medicine (2019) (10)
- Homology and Molecular Dynamics Models of Toll‐Like Receptor 7 Protein and Its Dimerization (2014) (10)
- Virtual Screening: An Overview on Methods and Applications (2011) (10)
- The molecular mechanism of action of methylene quinuclidinone and its effects on the structure of p53 mutants (2018) (10)
- Emergence of intrinsic representations of images by feedforward and feedback processes and bioluminescent photons in early retinotopic areas. (2010) (10)
- Symmetry breaking and bifurcating solutions in the classical complex phi6 field theory (1987) (10)
- An investigation of the plausibility of stochastic resonance in tubulin dimers (2012) (10)
- Gibbs Free Energy of Protein-Protein Interactions reflects tumor stage (2015) (9)
- On the Role of Microtubules in Cognitive Brain Functions (2007) (9)
- A unified approach to computational drug discovery. (2015) (9)
- In silico Investigations of the Mode of Action of Novel Colchicine Derivatives Targeting β-Tubulin Isotypes: A Search for a Selective and Specific β-III Tubulin Ligand (2020) (9)
- Modelling the Role of Intrinsic Electric Fields in Microtubules as an Additional Control Mechanism of Bi-directional Intracellular Transport (2008) (9)
- DFT studies of the electronic structure and geometry of 18-crown-6, hexaaza[18]annulene, and their complexes with cations of the heavier alkali and alkaline earth metals (2008) (9)
- Diatoms in space: testing prospects for reliable diatom nanotechnology in microgravity (2007) (9)
- Nonlinear assembly kinetics and mechanical properties of biopolymers (2005) (9)
- Physical interpretation of microtubule self-organization in gravitational fields (2005) (9)
- Synthesis and biological evaluation of structurally simplified noscapine analogues as microtubule binding agents (2017) (9)
- Nonlinear calcium ion waves along actin filaments control active hair-bundle motility (2018) (9)
- Probing the Basis of α-Synuclein Aggregation by Comparing Simulations to Single-Molecule Experiments. (2019) (8)
- Tubulin Polarizability in Aqueous Suspensions (2019) (8)
- The Bioelectric Circuitry of the Cell (2019) (8)
- Docosahexaenoic Acid Inhibits PTP1B Phosphatase and the Viability of MCF-7 Breast Cancer Cells (2019) (8)
- The efficacy of new colchicine derivatives and viability of the T-Lymphoblastoid cells in three-dimensional culture using 19F MRI and HPLC-UV ex vivo. (2009) (8)
- Phase transitions and structure analysis in wild-type, A30P, E46K, and A53T mutants of α-synuclein (2016) (8)
- Exact solutions to the time-dependent Landau-Ginzburg model of phase transitions (1984) (8)
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- Thermodynamic and Kinetic Stability of the Josephin Domain Closed Arrangement : Evidences from Replica Exchange (2017) (0)
- Electrolyte adsorption in graphene and hexagonal boron nitride nanochannels (2022) (0)
- University of Alberta “OMICs” Conference, June 17, 2013: Conference Program and Abstracts (2013) (0)
- Design principles for cancer therapy guided by changes in complexity of protein-protein interaction networks (2015) (0)
- Computational Prediction and Experimental Validation of the Unique Molecular Mode of Action of Scoulerine (2021) (0)
- ``Shooting Bead'' Method with Filament Energy Loss Consideration for Finding the Flexural Rigidity of the Rodelike Biological Filaments (2009) (0)
- Symmetries and soliton solutions of the Galilean complex Sine-Gordon equation (2016) (0)
- Soliton solutions describing propagation of charged particles in a system with self-inductance (1991) (0)
- Abstract 3725: Numerical simulation of tumor treating fields effects on cell structures: Mechanism and signaling pathway candidates (2019) (0)
- The physiological concentration of ferrous iron (II) alters the inhibitory effect of hydrogen peroxide on CD45, LAR and PTP1B phosphatases (2015) (0)
- Phase transitions and structure analysis in wild-type, A30P, E46K, and A53T mutants of α-synuclein (2015) (0)
- Thermodynamics and Cancer Dormancy: A Perspective (2017) (0)
- Synthesis and Evaluation of 1,5-Diaryl-Substituted Tetrazoles (IV) as Novel Selective Cyclooxygenase-2 (COX-2) Inhibitors. (2011) (0)
- Heat capacity singularity during induced spinodal decomposition (1991) (0)
- A Non-Linear Field Analysis of the Haldane Gap Problem for Quantum Spin Chains (1994) (0)
- Abstract 3195: The molecular mechanism of action and cellular targets of TTFields (2018) (0)
- Spin-correlated crystal fields: A study of two-body and relativistic effects for Gd3+ in lanthanum ethylsulphate (1988) (0)
- Real-Time Monitoring of the Effect of Tumour-Treating Fields on Cell Division Using Live-Cell Imaging (2022) (0)
- Structure of a Biological Cell (2003) (0)
- JACOBI ELLIPTIC SOLUTIONS OF THE QUINTIC NONLINEAR KLEIN-GORDON EQUATIONS (1988) (0)
- RDNA-01. TUBULIN AND MICROTUBULES AS MOLECULAR TARGETS FOR TTFIELD THERAPY (2019) (0)
- Melatonin mediates the reversibility of brain hyperphosphorylated tau protein induced by synthetic torpor in rats (2021) (0)
- Optical properties of a triangular Hubbard lattice (2002) (0)
- Quantum paradigms in psychopathology: multiscale investigations from biomolecular qubits to the brain, and its pathological states. (2021) (0)
- Centro-symmetric many-body Hamiltonians investigated with number-conserving operator equivalences and rotational symmetries (1999) (0)
- Designing Bcl-2 protein binding aptamers using an entropic fragment-based approach and in vitro validate the drug efficacy. (2023) (0)
- Drug discovery and Clinical Treatments (2018) (0)
- Death: An Unpredictable Variable of Time - Is the Impossible Possible? (2019) (0)
- Journal of Multiscale Neuroscience (2023) (0)
- Membrane-Based Nanotechnology and Drug Delivery (2012) (0)
- CSIG-26. IS INTRINSIC APOPTOSIS THE SIGNALING PATHWAY ACTIVATED BY TUMOR-TREATING FIELDS FOR GLIOBLASTOMA? (2019) (0)
- Nonlinear and Chaotic Phenomena in Plasmas, Solids and Fluids: Proceedings of the CAP-NSERC Summer Workshop in Theoretical Physics (1991) (0)
- Using Spectral Representation to Classify Proteins’ Conformational States (2018) (0)
- A strategy to identify housekeeping genes suitable for analysis in breast cancer diseases (2016) (0)
- From Nano to Neuro and Beyond (2014) (0)
- Molecular Insights in Psychiatry (2022) (0)
- Models of resonantly driven motion of motor proteins in 2D potentials (2005) (0)
- Excitation of Microtubules Using a Double Slit Ultrasound Device (2010) (0)
- Resonance Condition in Microtubules Using Ultrasound Plane Waves (2012) (0)
- What Is a Biological Cell? (2018) (0)
- Destabilizing the AXH tetramer by intra-and inter-dimer mutations : molecular mechanisms and potential (2017) (0)
- Scaling relations in the spherically symmetric Landau-Ginzburg model and a possible connection with self-organized criticality (1996) (0)
- 0 M ay 1 99 8 Noisy kink in microtubules (1998) (0)
- Stream of consciousness: Quantum and biochemical assumptions regarding psychopathology. (2017) (0)
- Lipid Membrane Binding of Computationally-Designed DNA Aptamers Specific for Phosphatidylserine (2013) (0)
- In silico investigation of molecular interactions of Volatile Anesthetics: Effects on phospholipid membranes and subcellular targets (2021) (0)
- COHERENT STRUCTURES IN QUANTUM SYSTEMS WITH TWO COUPLED TYPES OF EXCITATION (1998) (0)
- A physical model for microtubule polymerization (2008) (0)
- Aurintricarboxylic acid structure modifications lead to reduction of inhibitory properties against virulence factor YopH and higher cytotoxicity (2016) (0)
- Engineering of cytochrome P450 monooxygenases-based novel inhibitors against Mycobacterium tuberculosis (2014) (0)
- 2416-Pos Calculating Potentials of Mean Force for Large Biomolecules from Nonequilibrium Processes : Determination of Light Harvesting Complexes 2 Ring Sizes (2008) (0)
- Thermodynamic and kinetic stability of the Josephin Domain closed arrangement: evidences from replica exchange molecular dynamics (2017) (0)
- Galilean complex Sine-Gordon equation: symmetries, soliton solutions and gauge coupling (2017) (0)
- The Emergence of Structured, Living, and Conscious Matter in the Evolution of the Universe: A Theory of Structural Evolution and Interaction of Matter (2018) (0)
- Optical tweezers for drug discovery. (2022) (0)
- Maternal aspartame exposure and impact on offspring health : potential link to insulin resistance ? (2017) (0)
- Modelling the effective potential for persistent currents in annular discs of YBCO with coherent Josephson nanostructures (2002) (0)
- Abstract 5433: β-Tubulin inhibitors reduce GLUT1 membrane trafficking to attenuate tumorigenesis in glioblastoma subtypes (2017) (0)
- Novel Modes of Neural Computation: From Nanowires to Mind (2009) (0)
- Dual continuum upscaling of liver lobule flow and metabolism to the full organ scale (2022) (0)
- the Classical Vibrational Coherence of Carbonyl Groups in the Selectivity Filter Backbone of (2015) (0)
- A NEW APPROACH TO THE SEARCH FOR ANALYTICAL SOLUTIONS OF SECOND ORDER AUTONOMOUS NONLINEAR DIFFERENTIAL EQUATIONS (1993) (0)
- Boundaries of brain information processing (2010) (0)
- Description of the Normal-Roll Instability in Nematic Liquid Crystals Using a Generalized Potential Functional (1996) (0)
- Modelling the Dynamics of the Cytoskeleton's Protein Filaments (1999) (0)
- Improved calculations of magnetoelastic properties in collinear metamagnets (1988) (0)
- What Are Life Processes? (2018) (0)
- Abstract 3724: Molecular mechanisms of TTField action determined by measurements and modelling of electro-conductive properties of microtubules (2019) (0)
- Field- and frequency-dependent disassembly of polymerized and chemically stabilized microtubules by intense THz pulses (2022) (0)
- The role of domain walls in energy transfer mechanisms between two connected one-dimensional ferroelectrics (1991) (0)
- Gibbs Free Energy, a Thermodynamic Measure of Protein–Protein Interactions, Correlates with Neurologic Disability (2021) (0)
- Effect of Anesthetics on Collective London Dispersion Oscillations in Tubulin and its Implications for PostOperative Cognitive Dysfunction (2017) (0)
- Gibbs free energy as a measure of complexity correlates with time within C. elegans embryonic development (2017) (0)
- An Investigation of the Electron Transfer and Repulsive Coulomb Interactions in the One-, Two-, Three-Dimensional Isotropic Hubbard Models I:. Eigenfunctions and Eigenvalues (1998) (0)
- What Is Life? (2018) (0)
- Electric Conduction Effects in the Neuronal CytoskeletonHold the Key to Our Understanding of the Biophysics ofConsciousness (2018) (0)
- Davydov’s Soliton and Fröhlich’s Condensation: Is There a Connection? (1990) (0)
- Fröhlich Centenary International Symposium on Coherence and electric fields in biological systems (2005) (0)
- Editorial: Waves in fertilization, cell division and embryogenesis (2021) (0)
- Inclusion of finite-temperature effects in a nonlinear description of strongly interacting many-body systems (2000) (0)
- Supplementary material from "Cell death and survival due to cytotoxic exposure modelled as a two-state Ising system" (2020) (0)
- An Investigation of the Electron Transfer and Repulsive Coulomb Interactions in the One-, Two-, Three-Dimensional Isotropic Hubbard Models II: Extension to a Wannier and Higher Angular Momentum Basis (1998) (0)
- Linoleic acid: Is this the key that unlocks the quantum brain? Insights linking broken symmetries in molecular biology, mood disorders and personalistic emergentism (2017) (0)
- Quantum Capture in LB Monolayers and the Role of Thermal Fluctuations (1993) (0)
- Title Neural cytoskeleton capabilities for learning and memory Permalink (2009) (0)
- RTHP-14. TUMOR-TREATING FIELDS FOR GLIOBLASTOMA: NUMERICAL SIMULATION EXPLORES SUB-CELLULAR MECHANISMS (2018) (0)
- Nonlinear field analysis of the Hubbard model in one and two dimensions in the continuum limit (2000) (0)
- What Are the Molecules of Life? (2018) (0)
- Microbiota-Host Interactions , Aging and Stress Response : Diagnostic and Therapeutic Applications of the Physiological Fitness (2021) (0)
- Interplay between extended s-wave and d-wave superconductivity in the nonlinear field representation (1999) (0)
- Abstract 2663: CR42-24, a novel colchicine derivative, a therapeutic for bladder cancer (2018) (0)
- Comparative analyses and structural insights of the novel cytochrome P450 fusion protein family CYP5619 in Oomycetes (2018) (0)
- Altered cancer cell metabolism and cachexia: Calculating the energetic cost of cancer (2014) (0)
- A Solitonic Model for the “Information Strings” (1993) (0)
- A quantitative analysis of the frequency specrtum of the radiation emitted by cytochrome oxidase enzymes (2013) (0)
- Free Energy Calculations on the Binding of Colchicine and Its Derivatives with the α/β‐Tubulin Isoforms. (2008) (0)
- Abstract 3209: Numerical modeling of intracellular mechanisms in tumor-treating fields (2018) (0)
- From Quantum Biology Towards Quantum Consciousness (2021) (0)
- “Electroconductive Properties of Microtubules, Actin and Kinesin: Physical Force, Energy, Power and Information Considerations” (2018) (0)
- A directed binding model of motor protein motion on protein filaments (2007) (0)
- Comment on Activation of Visual Pigments by Light and Heat (Science 332, 1307-312, 2011) (2015) (0)
- Tubulin response to intense nanosecond-scale electric field in molecular dynamics simulation (2019) (0)
- Epilogue: Toward New Physics and New Biology (2003) (0)
- Acoustic phonon softening of selected double sulphates (1990) (0)
- Non-Gaussian statistics of the vibrational fluctuations of myoglobin and the thermal fluctuations of myoglobin hydration (2004) (0)
- Reflections of biological signaling: Electronic conduction may be an important intracellular pathway (1999) (0)
- Investigating the Structure of the XPF-ERCC1 Functional Endonuclease using a Computational Approach (2018) (0)
- Theoretical estimation of the breakage intensity of microtubules at resonance using ultrasound waves (2011) (0)
- EXTH-74. MOLECULAR MECHANISMS OF ANTI-TUMOR ACTION OF TTFIELDS DETERMINED BY MEASUREMENTS AND MODELING OF ELECTRO-CONDUCTIVE PROPERTIES OF MICROTUBULES (2018) (0)
- Microtubules as Sub-Cellular Memristors (2020) (0)
- Renormalization in Quantum Brain Dynamics (2023) (0)
- A Molecular Docking Study Reveals That Short Peptides Induce Conformational Changes in the Structure of Human Tubulin Isotypes αβI, αβII, αβIII and αβIV (2023) (0)
- Non-linearity and coherence in models of superconductivity (1991) (0)
- Molecular Biological Machines (2003) (0)
- Modeling the energetic cost of cancer as a result of altered energy metabolism: implications for cachexia (2015) (0)
- Discovering Boolean Functions on Actin Networks (2021) (0)
- Issue Information (2020) (0)
- Abstract 3076: Post-transcriptional regulatory mechanisms contributing to the evolution of paclitaxel resistance in breast cancer model cell line, SKBR3 (2015) (0)
- Molecular Models of Information Processing at the Levelof Individual Neurons and Their Significance (2012) (0)
- The electric resistivity of a magnetic semiconductor with easy-axis of anisotropy populated by magnon solitons (1991) (0)
- Targeting cancer drug resistance by modulation of ERCC1-XPF and p53 activity (2021) (0)
- Demystifying neuroblastoma malignancy through fractal dimension, entropy, and lacunarity. (2023) (0)
- Investigating the Electrical Properties of Microtubules (2004) (0)
- Development of Novel siRNA Therapeutics: A Review with a Focus on Inclisiran for the Treatment of Hypercholesterolemia (2023) (0)
- Instability of low-frequency oblique rolls in nematic liquid crystal thin films (1997) (0)
- Altered cancer cell metabolism and cachexia: Calculating the energetic cost of cancer (2014) (0)
- Mathematical Measures of Network Complexity for Cancer Signaling Networks (2015) (0)
- Biological Self-Regulation and Self-Organization (2003) (0)
- Computational Analysis and Experimental Testing of the Molecular Mode of Action of Gatastatin and Its Derivatives (2023) (0)
- Alteration of Consciousness by Anaesthetics: A Multiscale Modulation from the Molecular to the Systems Level (2022) (0)
- Computational Investigation of the Ordered Water System Around Microtubules: Implications for Protein Interactions (2022) (0)
- Signal Transmission in Carbon Nanotube Arrays (2011) (0)
- Nonequilibrium Thermodynamics and Biochemical Reactions (2003) (0)
- A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models (2016) (0)
- Molecular Dynamics Simulation Study of Intense Electric Field Effect on Tubulin (2018) (0)
- Biomedical Sciences Today: A platform for presenting latest research results to the scientific community and beyond (2015) (0)
- Editorial: The isotypes of α, β and γ tubulin: From evolutionary origins to roles in metazoan development and ligand binding differences (2023) (0)
- Computational molecular modelling as a platform for a deeper understanding of protein dynamics and rational drug design (2020) (0)
- Anesthetic Alterations of Collective Terahertz Oscillations in Tubulin Correlate with Clinical Potency: Implications for Anesthetic Action and Post-Operative Cognitive Dysfunction (2017) (0)
- Quantum Mechanisms of Electronic Signal Propagation Along a Microtubule (2011) (0)
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