John Macleod | Academic Influence

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John Macleod

Biology

#723

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Physiology

#37

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biology Degrees

John Macleod

Philosophy

#5453

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Biology
Philosophy

John Macleod 's Degrees

Doctorate Medicine University of Aberdeen

Why Is John Macleod Influential?

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According to Wikipedia, John James Rickard Macleod, , was a Scottish biochemist and physiologist. He devoted his career to diverse topics in physiology and biochemistry, but was chiefly interested in carbohydrate metabolism. He is noted for his role in the discovery and isolation of insulin during his tenure as a lecturer at the University of Toronto, for which he and Frederick Banting received the 1923 Nobel prize in Physiology or Medicine. Awarding the prize to Macleod was controversial at the time, because according to Banting's version of events, Macleod's role in the discovery was negligible. It was not until decades after the events that an independent review acknowledged a far greater role than was attributed to him at first.

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John Macleod 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

INSULIN AND DIABETES (1922) (100)
THE EFFECT OF PANCREATIC EXTRACT (INSULIN) ON NORMAL RABBITS (1922) (95)
Physiology and Biochemistry in Modern Medicine (1920) (73)
Macleod's physiology in modern medicine (1938) (72)
Carbohydrate metabolism and insulin (57)
Behaviour of Depancreatized Dogs kept Alive with Insulin (1924) (53)
THE OUTFLOW OF BLOOD FROM THE LIVER AS AFFECTED BY VARIATIONS IN THE CONDITION OF THE PORTAL VEIN AND HEPATIC ARTERY (1914) (43)
THE EFFECTS OF INSULIN ON EXPERIMENTAL HYPERGLYCEMIA IN RABBITS (1922) (33)
STUDIES IN EXPERIMENTAL GLYCOSURIA. XII: Lactic Acid Production in the Blood Following the Injection of Alkaline Solutions of Dextrose or of Alkaline Solutions Alone (1917) (27)
Studies on diffusion through surviving isolated intestine (1930) (26)
INFLUENCE OF INSULIN ON LIVER AND MUSCLE GLYCOGEN IN THE RAT UNDER VARYING NUTRITIONAL CONDITIONS (1927) (23)
THE INFLUENCE OF SUGARS AND OTHER SUBSTANCES ON THE TOXIC EFFECTS OF INSULIN (1923) (21)
Does insulin influence the glycogenic function of the perfused liver of the turtle? (1923) (21)
A further enquiry into the supposed existence of cerebral vasomotor nerves (1901) (21)
Selective absorption of carbohydrates (1930) (21)
THE INFLUENCE OF ALKALI ADMINISTRATION ON THE URINARY EXCRETION OF LACTIC ACID, AND THE POSSIBLE SIGNIFICANCE OF THE LATTER IN MAINTAINING NEUTRALITY IN THE BODY (1918) (20)
The influence of compressed air on the respiratory exchange (1903) (20)
WHITE CELL MORPHOLOGY IN RABBITS WITH INDUCED PERITONEAL EXUDATES (1938) (19)
BLOOD GLYCOLYSIS: ITS EXTENT AND SIGNIFICANCE IN CARBOHYDRATE METABOLISM. THE SUPPOSED EXISTENCE OF "SUCRE VIRTUEL" IN FRESHLY DRAWN BLOOD (1913) (18)
The influence of the nutritional condition of the animal on the hypoglycæmia produced by insulin (1923) (18)
STUDIES IN EXPERIMENTAL GLYCOSURIA: XI. Retention of Dextrose by the Liver and Muscles and the Influence of Acids and Alkalies on the Dextrose Concentration of the Blood (17)
THE CONTROL OF CARBOHYDRATE METABOLISM. (1932) (16)
OBSERVATIONS ON DEPANCREATISED DOGS BEFORE AND AFTER THE WITHDRAWAL OF INSULIN (1925) (16)
Caisson Illness and Diver's Palsy. An Experimental Study (1903) (16)
INSULIN AND GLYCOLYSIS (1923) (16)
Studies in the Nervous Control of Carbohydrate Metabolism. I.--The Position of the Centre (1932) (16)
THE PHYSIOLOGICAL ASSAY OF INSULIN BASED ON ITS EFFECTS ON THE HYPERGLYCEMIA FOLLOWING GLUCOSE INJECTIONS AND EPINEPHRIN (1923) (14)
Diabetes : its pathological physiology (14)
THE RELATIONSHIP BETWEEN NERVOUS AND HORMONE CONTROL OF THE RESPIRATORY CENTER (1922) (14)
The Efficiency of Various Sugars and their Derivatives in Relieving the Symptoms caused by Insulin in Mice. (14)
THE EFFECT OF INSULIN ON THE RESPIRATORY EXCHANGE OF FED AND FASTING RABBITS (1927) (14)
Solvent water in the mammalian erythrocyte (1936) (13)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—VI. THE DISTRIBUTION OF GLYCOGEN OVER THE LIVER UNDER VARIOUS CONDITIONS. POST MORTEM GLYCOGENOLYSIS (1911) (13)
THE SUGAR OF ARTERIAL AND VENOUS BLOOD DURING THE ACTION OF INSULIN (1924) (12)
THE SUGAR CONSUMPTION IN NORMAL AND DIABETIC (DEPANCREATED) DOGS AFTER EVISCERATION (1913) (12)
THE EFFECT OF INSULIN ON THE RESPIRATORY EXCHANGE OF NORMAL ANIMALS (1924) (12)
A Case of Multiple Myeloma (Myelomatosis) with Bence-Jones Proteid in the Urine (Myelopathic Albumosuria of Bradshaw, Kahler's Disease),and a Summary of Published Cases of Bence-Jones Albumosuria: With a Report on the Chemical Pathology. (11)
STUDIES IN EXPERIMENTAL GLYCOSURIA: IX. The Level of the Blood-Sugar in the Dog Under Laboratory Conditions (1915) (11)
The fuel of life (11)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—IV. THE CAUSE OF THE HYPERGLYCÆMIA PRODUCED BY ASPHYXIA (11)
FURTHER EXPERIMENTS ON THE ACTION OF INSULIN (1925) (11)
THE POTENTIAL AND RESPIRATION OF FROG SKIN : I. THE EFFECT OF THE HOMOLOGOUS CARBAMATES. II. THE EFFECT OF CERTAIN LYSINS. (1937) (11)
OBSERVATIONS ON THE REDUCING SUBSTANCE IN THE CIRCULATING FLUIDS OF CERTAIN INVERTEBRATES AND FISHES (1920) (10)
THE EFFECT OF HEMOLYTIC SUBSTANCES ON WHITE CELL RESPIRATION (1936) (10)
The immediate products of post‐mortem glycogenolysis in mammalian muscle and liver (1927) (9)
The Chemical Constitution of the Tubercle Bacillus (1904) (9)
The concentration of lactic acid in the blood in anoxemia and shock (9)
Pancreatic Extract and Diabetes. (1922) (8)
FURTHER OBSERVATIONS ON THE RATE AT WHICH SUGAR DISAPPEARS FROM THE BLOOD OF EVISCERATED ANIMALS (1914) (8)
OBSERVATIONS ON THE EXCRETION OF CARBON DIOXIDE GAS AND THE RECTAL TEMPERATURE OF RATS KEPT IN A WARM ATMOSPHERE WHICH WAS EITHER VERY MOIST OR VERY DRY (1907) (8)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—II. SOME EXPERIMENTS BEARING ON THE NATURE OF THE GLYCOGENOLYTIC FIBRES IN THE GREAT SPLANCHNIC NERVE (1908) (8)
DIABETES AS A PHYSIOLOGICAL PROBLEM (1930) (7)
Insulin and increase in weight of young animals. (7)
STUDIES IN EXPERIMENTAL GLYCOSURIA: X. The Sugar Retaining Power of the Liver in Relationship to the Amount of Glycogen Already Present in the Organ (1915) (7)
STUDIES IN EXPERIMENTAL GLYCOSURIA. — V. THE DISTRIBUTION OF GLYCOGENOLYTIC FERMENT IN THE ANIMAL BODY, ESPECIALLY OF THE DOG (7)
EFFECTS OF HOT AND COLD APPLICATIONS TO THE SURFACE OF THE BODY: ON THE TEMPERATURE OF THE MUSCLES, LIVER, KIDNEYS AND BRAIN.1 (1921) (7)
The measurement of red cell volume (1933) (7)
STUDIES ON NUTRITION IN RELATION TO IMMUNITY.: A PRELIMINARY COMMUNICATION (1931) (7)
Insulin and the steps taken to secure an effective preparation. (1922) (6)
EVIDENCE THAT THE ACTIVE PRINCIPLE OF THE RETRO-PERITONEAL CHROMAPHIL TISSUE HAS THE SAME PHYSIOLOGICAL ACTION AS THE ACTIVE PRINCIPLE OF THE SUPRARENAL GLANDS (1916) (6)
Insulin : its use in the treatment of diabetes (6)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—VIII. THE RELATIONSHIP OF THE ADRENAL GLANDS TO SUGAR PRODUCTION BY THE LIVER (1912) (6)
PERIODIC BREATHING AND THE EFFECTS OF OXYGEN ADMINISTRATION IN DECEREBRATE CATS (1921) (6)
Studies in the Nervous Control of Carbohydrate Metabolism. III.--The Nature of the Mechanism of the Nerve Control (1932) (5)
The influence of compressed air and oxygen on the gases of the blood (1903) (5)
Glycosuria and Allied Conditions (1913) (5)
The Antidiabetic Functions of the Pancreas and Successful Isolation of the Antidiabetic Hormone Insulin (1924) (4)
OXYGEN CONSUMPTION OF WHITE CELLS FROM PERITONEAL EXUDATES (1938) (4)
A Lecture on INSULIN (1923) (4)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—I. ON THE EXISTENCE OF AFFERENT AND EFFERENT NERVE FIBRES, CONTROLLING THE AMOUNT OF SUGAR IN THE BLOOD (1907) (4)
EFFECTS OF HOT AND COLD APPLICATIONS ON THE SUPERFICIAL AND DEEP TEMPERATURES. (1920) (4)
The influence of high pressures of oxygen on the circulation of the blood (3)
THE EFFECT OF SHIVERING ON THE RESPIRATORY QUOTIENT IN PANCREATIC DIABETES (1929) (3)
Studies in the Nervous Control of Carbohydrate Metabolism. II.--The Chemical Changes Set up in the Body during Decerebration Hyperglycaemia (1932) (3)
MULTIPLE MYELOMA (MYELOMATOSIS), WITH BENCE-JONES PEOTEID IN THE URINE: MYELOPATHIC ALBUMOSURIA OF BRADSHAW, KAHLER'S DISEASE (1903) (3)
No. 19: THE IMMEDIATE POST MORTEM CHANGES IN FISH MUSCLE (3)
THE BEHAVIOR OF THE SUGAR AND LACTIC ACID IN THE BLOOD FLOWING FROM THE LIVER, AFTER TEMPORARY OCCLUSION OF THE HEPATIC PEDICLE (1914) (3)
Cameron Prize Lectures ON THE NATURE OF CONTROL OF THE METABOLISM OF CARBOHYDRATES IN THE ANIMAL BODY (1924) (3)
The effect of evisceration on the respiratory metabolism of the decerebrate preparation (1931) (3)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—VII. THE AMOUNT OF GLYCOGENASE IN THE LIVER AND IN THE BLOOD ISSUING FROM IT, AS AFECTED BY STIMULATION OF THE GREAT SPLANCHNIC NERVE (1911) (3)
Gluconeogenesis and the energy material of muscle. (1932) (3)
VARIOUS FORMS OF EXPERIMENTAL DIABETES AND THEIR SIGNIFICANCE FOR DIABETES MELLITUS (1910) (2)
The glycogen of mammalian muscle and its behaviour after death. (2)
Methods of Study of Early Diabetes. (2)
SOME OBSERVATIONS ON THE EFFECT OF ALTERNATING CURRENTS OF MODERATE FREQUENCY ON DOGS (1905) (2)
GLANDULAR THERAPY PANCREATIC GLAND PREPARATIONS: I. PHYSIOLOGY (1924) (2)
RECENT WORK ON THE PHYSIOLOGIC PATHOLOGY OF GLYCOSURIA (1914) (2)
Post-mortem changes in the free sugar, glycogen, phosphates and lactic acid in mammalian muscle (1926) (2)
The influence of an atmosphere of oxygen on the respiratory exchange (2)
THE EFFECT OF EXPRESSED TISSUE JUICES OF MUSCLE ON THE MAMMALIAN HEART BEAT (1907) (1)
SOME OBSERVATIONS ON THE BEHAVIOR OF THE ENDOGENOUS PURIN EXCRETION IN MAN (1906) (1)
STUDIES IN EXPERIMENTAL GLYCOSURIA.—NO. III THE INFLUENCE OF STMULATION OF THE GREAT SPLANCHNIC NERVE ON THE RATE OF DISAPPEARANCE OF GLYCOGEN FROM THE LIVER, DEPRIVED OF ITS PORTAL BLOOD SUPPLY OR OF BOTH ITS PORTAL AND SYSTEMIC BLOOD SUPPLIES (1908) (1)
Address on ???Insulin??? (1923) (1)
THE QUANTITATIVE ESTIMATION OF CARBAMATES (1905) (1)
Insulin (1924) (1)
The Problem of the Fundamental Action of Insulin. (1925) (1)
Endogene Hyperglykämie (experimenteller Diabetes) (1)
The hydrolysis of fats in vitro by means of steapsin (1)
SOME OBSERVATIONS ON THE EFFECTS OF ANOXEMIA ON THE RESPIRATORY CENTER IN DECEREBRATE ANIMALS (1921) (1)
The effect on the normal dog heart of expressed tissue juice from hearts of dogs poisoned with diphtheria toxin (1906) (0)
A COMPARISON OF THE METHODS OF REID AND SCHENCK FOR QUANTITATIVE ESTIMATION OF THE REDUCING SUBSTANCES IN BLOOD (0)
Human physiology : especially adapted for dental students (0)
The relationship of the left suprarenal capsule to the sugar production of the liver in dogs (1911) (0)
Discussion on “The Use of Insulin in General Practice.” (1924) (0)
The Underlying Principles of Ventilation (0)
Further observations on the effect of asphyxia and curare on the reducing power of the blood after section of the hepatic nerves in dogs (1909) (0)
No. 20: THE RELATIONSHIP BETWEEN RIGOR MORTIS AND THE GLYCOGEN, LACTIC ACID AND FREE PHOSPHORUS OF FISH MUSCLE (0)
On the supposed existence of efferent fibers from the diabetic center to the liver (1906) (0)
Physiology and biochemistry in modern medicine / by J.J.R. Macleod; assisted by Roy G. Pearce ... [et al.]. (0)
Medical Education. (0)
Insulin and its Value in Medicine (1923) (0)
The spontaneous development of an acidosis condition in decerebrate cats (1918) (0)
Physiology and biochemistry in modern medicine / by J.J.R. Macleod ... assisted by Roy G. Pearce, ... and by others (0)
The Chemical Control of Respiration. (0)
The behaviour of the respirations after decerebration in the cat (0)
ALLOXURIC EXCRETION IN A CASE OF LEUCOPENIA (1901) (0)
The fuel of life : experimental studies in normal and diabetic animals (0)
Physiology of the Intracranial Circulation. (1918) (0)
THE INSTITUTES OF MEDICINE. (1928) (0)
The principles involved in the economic readjustment of dietaries (1917) (0)
THE TEACHING OF PHYSIOLOGY TO MEDICAL STUDENTS. (1914) (0)
Human physiology, especially adapted for dental students, by R. G. Pearce ... and J. J. R. Macleod ... Fifty-nine illustrations, including ten color plates. (0)
Harvey’s Experiments on Circulation* An address delivered at the tercentenary celebration of the publication of Harvey’s book on the circulation of the blood by the College of Physicans, Philadelphia, March 22-23, 1928. (1928) (0)
Contribution to our Knowledge of the Chemistry of Red Bone Marrow. (1902) (0)
The stimulating influence of alkali on hepatic glycogenesis (1916) (0)
THE ALLEGED EFFECT OF ELECTRICAL STIMULATION ON THE METABOLISM OF RED CELL SUSPENSIONS (1935) (0)
A RESEARCH INSTITUTE FOR SURGEONS. (1931) (0)
THE ESTIMATION OF FREE HYDROCHLORIC ACID IN THE GASTRIC CONTENTS. (1903) (0)
Medical Education. (0)
Changes occurring in mammalian muscle immediately after death. (1926) (0)
The glycogenolytic strength of blood serum from the pancreatico-duodenal vein and from the femoral artery, and of lymph from the thoracic duct, as affected by stimulation of the great splanchnic nerve (1910) (0)
Physiology and Clinical Medicine. (0)
On the nature of the socalled glycogenolytic fibers in the greater splanchnic nerves (1908) (0)
THE POTENTIAL AND RESPIRATION OF FROG SKIN (1937) (0)

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