Melanie Brinkmann

Melanie Brinkmann's AcademicInfluence.com Rankings

Melanie Brinkmann

Biology

#1794

World Rank

#2914

Historical Rank

Virology

#77

World Rank

#80

Historical Rank

biology Degrees

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Biology

Melanie Brinkmann's Degrees

PhD Virology Hannover Medical School
Masters Biology University of Göttingen

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Why Is Melanie Brinkmann Influential?

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According to Wikipedia, Melanie Brinkmann is a German virologist. Until 2019 she was probably best known in connection with her work on the Cytomegalovirus. During 2020 she has emerged as a much consulted expert-pundit for media commentators keen to discuss the COVID-19 pandemic. Brinkmann takes a robust public position in the campaign against pandemic misinformation: she has described the so-called "virus of false information" as "more deadly than the [COVID-19] virus itself".

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Melanie Brinkmann's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes (2008) (670)
Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9 (2008) (491)
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling (2007) (439)
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. (2012) (305)
Granulin is a soluble cofactor for toll-like receptor 9 signaling. (2011) (170)
Activation of Mitogen-Activated Protein Kinase and NF-κB Pathways by a Kaposi's Sarcoma-Associated Herpesvirus K15 Membrane Protein (2003) (145)
Regulation of intracellular signalling by the terminal membrane proteins of members of the Gammaherpesvirinae. (2006) (115)
Cytoplasmic isoforms of Kaposi sarcoma herpesvirus LANA recruit and antagonize the innate immune DNA sensor cGAS (2016) (114)
Murine B Cell Response to TLR7 Ligands Depends on an IFN-β Feedback Loop1 (2009) (112)
SARS‐CoV‐2 outbreak investigation in a German meat processing plant (2020) (107)
Kaposi's Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G1 Cell CycleArrest (2006) (102)
Viral Mediated Redirection of NEMO/IKKγ to Autophagosomes Curtails the Inflammatory Cascade (2012) (92)
Modulation of Host Gene Expression by the K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus (2006) (89)
An action plan for pan-European defence against new SARS-CoV-2 variants (2021) (86)
The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport (2018) (78)
The herpesviral antagonist m152 reveals differential activation of STING‐dependent IRF and NF‐κB signaling and STING's dual role during MCMV infection (2019) (69)
Calling for pan-European commitment for rapid and sustained reduction in SARS-CoV-2 infections (2020) (64)
Age-Dependent Enterocyte Invasion and Microcolony Formation by Salmonella (2014) (61)
The Gammaherpesviruses Kaposi's Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus 68 Modulate the Toll-Like Receptor-Induced Proinflammatory Cytokine Response (2014) (52)
Investigation of a superspreading event preceding the largest meat processing plant-related SARS-Coronavirus 2 outbreak in Germany (2020) (50)
Coevolution pays off: Herpesviruses have the license to escape the DNA sensing pathway (2019) (49)
Role of the Kaposi's Sarcoma-Associated Herpesvirus K15 SH3 Binding Site in Inflammatory Signaling and B-Cell Activation (2010) (38)
Cell-Specific TLR9 Trafficking in Primary APCs of Transgenic TLR9-GFP Mice (2013) (37)
Large-scale purification, dissociation and functional reassembly of the maltose ATP-binding cassette transporter (MalFGK2) of Salmonella typhimurium (2002) (37)
Growing tumors induce a local STING dependent Type I IFN response in dendritic cells (2016) (33)
Functional characterization of the M-type K15-encoded membrane protein of Kaposi's sarcoma-associated herpesvirus. (2007) (32)
A multinational Delphi consensus to end the COVID-19 public health threat (2022) (31)
Cytomegalovirus immune evasion of myeloid lineage cells (2015) (31)
IRAP+ endosomes restrict TLR9 activation and signaling (2017) (30)
Acidic Amino Acid Residues in the Juxtamembrane Region of the Nucleotide-Sensing TLRs Are Important for UNC93B1 Binding and Signaling (2013) (29)
Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1γ (2013) (26)
The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription (2017) (23)
The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi’s sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein (2018) (22)
Of Keeping and Tipping the Balance: Host Regulation and Viral Modulation of IRF3-Dependent IFNB1 Expression (2020) (21)
Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection (2018) (19)
TLRs bent into shape (2007) (18)
The Zinc Finger Antiviral Protein ZAP Restricts Human Cytomegalovirus and Selectively Binds and Destabilizes Viral UL4/UL5 Transcripts (2021) (17)
Large-scale purification, dissociation and functional reassembly of the maltose ATP-binding cassette transporter (MalFGK(2)) of Salmonella typhimurium. (2002) (17)
One Step Ahead: Herpesviruses Light the Way to Understanding Interferon-Stimulated Genes (ISGs) (2020) (15)
Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus. (2009) (13)
CD82 controls CpG‐dependent TLR9 signaling (2019) (12)
Strategies for immune evasion by human tumor viruses. (2018) (12)
The Cytomegalovirus Tegument Protein UL35 Antagonizes Pattern Recognition Receptor-Mediated Type I IFN Transcription (2020) (12)
The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages (2016) (11)
Functional expression of TLR5 of different vertebrate species and diversification in intestinal pathogen recognition (2018) (11)
In Vivo Visualizing the IFN-β Response Required for Tumor Growth Control in a Therapeutic Model of Polyadenylic-Polyuridylic Acid Administration (2016) (11)
A highly conserved redox-active Mx(2)CWx(6)R motif regulates Zap70 stability and activity (2017) (9)
Murine cytomegaloviruses m139 targets DDX3 to curtail interferon production and promote viral replication (2020) (8)
Viral infection of the ovaries compromises pregnancy and reveals innate immune mechanisms protecting fertility. (2021) (4)
Cytomegalovirus immune evasion of myeloid lineage cells (2015) (3)
UNC93B1 Is Widely Expressed in the Murine CNS and Is Required for Neuroinflammation and Neuronal Injury Induced by MicroRNA let-7b (2021) (3)
Type I Interferon Signaling Controls Gammaherpesvirus Latency In Vivo (2022) (3)
Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K 15 gene of Kaposi ’ s sarcoma-associated herpesvirus (2009) (3)
The Kaposi ’ s Sarcoma-Associated Herpesvirus LANA-1 interacts with the short variant of BRD 4 1 and releases cells from a BRD 4-and BRD 2 / RING 3-induced G 1 cell cycle arrest . 2 3 4 (2006) (3)
Measurement of mouse cytomegalovirus-induced interferon-β with immortalized luciferase reporter cells. (2013) (2)
Characterisation of the KSHV protein ORF20 and its role in innate immunity (2)
The role ofTLR2 in infection and immunity (2012) (2)
Protein tyrosine phosphatase 1B (PTP1B) is involved in efficient type I interferon secretion upon viral infection. (2020) (1)
Protein tyrosine phosphatase 1B is involved in efficient type I interferon secretion upon viral infection (2020) (1)
The zinc finger antiviral protein ZAP destabilises viral transcripts and restricts human cytomegalovirus (2020) (1)
UNC93B1 Binding and Signaling Nucleotide-Sensing TLRs Are Important for Juxtamembrane Region of the Acidic Amino Acid Residues in the (2013) (0)
The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection (2023) (0)
This information is current as Feedback Loop β Depends on an IFN-Murine B Cell Response to TLR 7 Ligands (2009) (0)
Cell Cycle Arrest 1 BRD 2 / RING 3-Induced G BRD 4 and Releases Cells from a BRD 4-and LANA-1 Interacts with the Short Variant of Kaposi ' s Sarcoma-Associated Herpesvirus (2006) (0)
The two faces of oligoadenylate synthetase-like: effective antiviral protein and negative regulator of innate immunity. (2023) (0)
The endosomal Toll-like receptors 7 and 9 cooperate in detection of MHV 68 1 infection 2 (2018) (0)
The Cytomegalovirus M35 Protein Modulates Transcription of Ifnb1 and Other IRF3-Driven Genes by Direct Promoter Binding (2023) (0)
Expression of NKG2D ligand by cytomegalovirus enhances its vaccine vector capacity (2012) (0)
Acidic residues in the juxta-transmembrane region of toll-like receptor 9 are crucial for binding UNC93B1 (68.12) (2012) (0)
Coevolution pays off: Herpesviruses have the license to escape the DNA sensing pathway (2019) (0)
UNC 93 B 1 Binding and Signaling Nucleotide-Sensing TLRs Are Important for Juxtamembrane Region of the Acidic Amino Acid Residues in the (2013) (0)
Kaposi’s Sarcoma-Associated Herpesvirus LANA-1 Interacts with the Short Variant of BRD4 and Releases Cells from a BRD4- and BRD2/RING3-Induced G 1 Cell Cycle Arrest (cid:1) (2006) (0)
Acknowledgement to reviewers (2017) (0)
RAE-1γ ligand expression by MCMV vector promotes induction and maintenance of protective immune memory (2015) (0)
231: Type I interferon controls gammaherpesvirus latency (2013) (0)
LC3-associated phagocytosis mediates IFN-alpha secretion in response to DNA-immune complexes. (BA3P.207) (2014) (0)
Recent advances in understanding Kaposi ’ s sarcoma-associated herpesvirus (2019) (0)
Functional expression of TLR5 of different vertebrate species and diversification in intestinal pathogen recognition (2018) (0)
Novel role of bone morphogenetic protein 9 (BMP9) in innate host responses to HCMV infection (2023) (0)
ID: 76: The MCMV protein M35 is a novel negative regulator of the type I IFN response (2015) (0)
APCs of Transgenic TLR9-GFP Mice Cell-Specific TLR9 Trafficking in Primary (2012) (0)
Call for a pan-European COVID-19 response must be comprehensive – Authors' reply (2021) (0)

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Melanie Brinkmann's Academic­Influence.com Rankings