Molly Shoichet
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Canadian biomedical engineer
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Molly Shoichetengineering Degrees
Engineering
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Biomedical Engineering
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Engineering
Why Is Molly Shoichet Influential?
(Suggest an Edit or Addition)According to Wikipedia, Molly S. Shoichet , is a Canadian science professor, specializing in chemistry, biomaterials and biomedical engineering. She was Ontario's first Chief Scientist. Shoichet is a biomedical engineer known for her work in tissue engineering, and is the only person to be a fellow of the three National Academies in Canada.
Molly Shoichet's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A photolabile hydrogel for guided three-dimensional cell growth and migration (2004) (726)
- Polymeric micelle stability (2012) (639)
- The effect of substrate stiffness on adult neural stem cell behavior. (2009) (595)
- Controlling cell adhesion and degradation of chitosan films by N-acetylation. (2005) (545)
- Fast-gelling injectable blend of hyaluronan and methylcellulose for intrathecal, localized delivery to the injured spinal cord. (2006) (525)
- Engineering three-dimensional bone tissue in vitro using biodegradable scaffolds: investigating initial cell-seeding density and culture period. (2000) (479)
- Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels. (2011) (456)
- Polymer Scaffolds for Biomaterials Applications (2010) (429)
- Peripheral nerve regeneration through guidance tubes (2004) (402)
- Diels-Alder Click cross-linked hyaluronic acid hydrogels for tissue engineering. (2011) (344)
- Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury (2019) (281)
- Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells. (2008) (277)
- Stability of hydrogels used in cell encapsulation: An in vitro comparison of alginate and agarose (1996) (274)
- Chitin-based tubes for tissue engineering in the nervous system. (2005) (264)
- Stability of Self-Assembled Polymeric Micelles in Serum (2011) (252)
- Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering. (2005) (242)
- Immobilized concentration gradients of neurotrophic factors guide neurite outgrowth of primary neurons in macroporous scaffolds. (2006) (222)
- In vitro degradation of a novel poly(lactide-co-glycolide) 75/25 foam. (1999) (219)
- Immobilized concentration gradients of nerve growth factor guide neurite outgrowth. (2004) (218)
- Macroporous interconnected dextran scaffolds of controlled porosity for tissue-engineering applications. (2005) (217)
- Optimizing the sterilization of PLGA scaffolds for use in tissue engineering. (2001) (215)
- A hydrogel-based stem cell delivery system to treat retinal degenerative diseases. (2010) (212)
- Repair of the injured spinal cord by transplantation of neural stem cells in a hyaluronan-based hydrogel. (2013) (210)
- Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. (2006) (209)
- Regenerative Therapies for Central Nervous System Diseases: a Biomaterials Approach (2014) (208)
- Manufacture of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) hydrogel tubes for use as nerve guidance channels. (2002) (205)
- Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube. (2003) (204)
- Injectable hydrogels for central nervous system therapy (2012) (195)
- Bioengineered strategies for spinal cord repair. (2006) (192)
- Differentiation of neural stem cells in three-dimensional growth factor-immobilized chitosan hydrogel scaffolds. (2011) (192)
- An injectable drug delivery platform for sustained combination therapy. (2009) (188)
- Bone formation on two-dimensional poly(DL-lactide-co-glycolide) (PLGA) films and three-dimensional PLGA tissue engineering scaffolds in vitro. (2003) (181)
- A Hyaluronan-Based Injectable Hydrogel Improves the Survival and Integration of Stem Cell Progeny following Transplantation (2015) (180)
- Synthetic hydrogel guidance channels facilitate regeneration of adult rat brainstem motor axons after complete spinal cord transection. (2004) (178)
- Tunable Growth Factor Delivery from Injectable Hydrogels for Tissue Engineering (2011) (176)
- Fiber templating of poly(2-hydroxyethyl methacrylate) for neural tissue engineering. (2003) (175)
- Design of three-dimensional biomimetic scaffolds. (2010) (175)
- Regenerative biomaterials that "click": simple, aqueous-based protocols for hydrogel synthesis, surface immobilization, and 3D patterning. (2011) (175)
- Defining the concentration gradient of nerve growth factor for guided neurite outgrowth (2001) (173)
- Intrathecal delivery of a polymeric nanocomposite hydrogel after spinal cord injury. (2010) (172)
- Doxorubicin‐Conjugated Immuno‐Nanoparticles for Intracellular Anticancer Drug Delivery (2009) (171)
- Promoting neuron adhesion and growth (2008) (166)
- Peptide surface modification of methacrylamide chitosan for neural tissue engineering applications. (2007) (148)
- The generation of the epicardial lineage from human pluripotent stem cells (2014) (146)
- Three-dimensional Chemical Patterning of Transparent Hydrogels (2008) (145)
- Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates longterm teratoma formation in a spinal cord injury model. (2016) (145)
- Colloidal Aggregation Affects the Efficacy of Anticancer Drugs in Cell Culture (2012) (140)
- Synthesis of cell-adhesive dextran hydrogels and macroporous scaffolds. (2006) (139)
- Use of a biomimetic strategy to engineer bone. (2003) (135)
- Hydrogel delivery of erythropoietin to the brain for endogenous stem cell stimulation after stroke injury. (2012) (132)
- Extramedullary chitosan channels promote survival of transplanted neural stem and progenitor cells and create a tissue bridge after complete spinal cord transection. (2008) (128)
- Clip Compression Model Is Useful for Thoracic Spinal Cord Injuries: Histologic and Functional Correlates (2007) (126)
- A new paradigm for local and sustained release of therapeutic molecules to the injured spinal cord for neuroprotection and tissue repair. (2009) (126)
- Bioengineered sequential growth factor delivery stimulates brain tissue regeneration after stroke. (2013) (120)
- Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels. (2007) (119)
- Patterned glass surfaces direct cell adhesion and process outgrowth of primary neurons of the central nervous system. (1998) (119)
- The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate. (2012) (119)
- A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction (2019) (115)
- Injectable intrathecal delivery system for localized administration of EGF and FGF-2 to the injured rat spinal cord (2005) (114)
- Designer protein delivery: From natural to engineered affinity-controlled release systems (2016) (112)
- Long-term in vivo biomechanical properties and biocompatibility of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) nerve conduits. (2005) (112)
- Controlled epi-cortical delivery of epidermal growth factor for the stimulation of endogenous neural stem cell proliferation in stroke-injured brain. (2011) (112)
- Hybrid Crosslinked Methylcellulose Hydrogel: A Predictable and Tunable Platform for Local Drug Delivery (2015) (112)
- Affinity-based drug delivery systems for tissue repair and regeneration. (2014) (111)
- Engineering Cellular Microenvironments with Photo- and Enzymatically Responsive Hydrogels: Toward Biomimetic 3D Cell Culture Models. (2017) (111)
- Biomaterials for cell transplantation (2018) (110)
- Combinatorial Therapies After Spinal Cord Injury: How Can Biomaterials Help? (2017) (109)
- Characterization of neural stem cells on electrospun poly(ε-caprolactone) submicron scaffolds: evaluating their potential in neural tissue engineering (2008) (108)
- Fibrin-filled scaffolds for bone-tissue engineering: An in vivo study. (2004) (107)
- Colloidal Drug Formulations Can Explain “Bell-Shaped” Concentration–Response Curves (2014) (106)
- Click chemistry functionalized polymeric nanoparticles target corneal epithelial cells through RGD-cell surface receptors. (2009) (106)
- Endothelial Cell Guidance in 3D Patterned Scaffolds (2010) (104)
- Investigating the synergistic effect of combined neurotrophic factor concentration gradients to guide axonal growth (2003) (104)
- Immuno-polymeric nanoparticles by Diels-Alder chemistry. (2007) (104)
- Scaffolds for Tissue Engineering (2003) (104)
- Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles (2016) (103)
- Light-activated immobilization of biomolecules to agarose hydrogels for controlled cellular response. (2004) (103)
- Biomaterials for Brain Tissue Engineering (2010) (100)
- Creating permissive microenvironments for stem cell transplantation into the central nervous system. (2012) (100)
- Hyaluronic acid click hydrogels emulate the extracellular matrix. (2013) (99)
- Nerve guidance channels as drug delivery vehicles. (2006) (96)
- Cell and biomolecule delivery for tissue repair and regeneration in the central nervous system. (2014) (93)
- A covalently modified hydrogel blend of hyaluronan–methyl cellulose with peptides and growth factors influences neural stem/progenitor cell fate (2012) (92)
- Affinity-based release of chondroitinase ABC from a modified methylcellulose hydrogel. (2013) (92)
- The effect of immobilized platelet derived growth factor AA on neural stem/progenitor cell differentiation on cell-adhesive hydrogels. (2008) (92)
- Enhancing the neuronal interaction on fluoropolymer surfaces with mixed peptides or spacer group linkers. (2001) (91)
- Chemically-bound nerve growth factor for neural tissue engineering applications (2003) (91)
- Diels-Alder Click-Cross-Linked Hydrogels with Increased Reactivity Enable 3D Cell Encapsulation. (2018) (91)
- Incorporation of protein-eluting microspheres into biodegradable nerve guidance channels for controlled release. (2006) (90)
- Designing Peptide and Protein Modified Hydrogels: Selecting the Optimal Conjugation Strategy. (2017) (90)
- Design of biomaterials to enhance stem cell survival when transplanted into the damaged central nervous system (2010) (90)
- Enhanced neurotrophin-3 bioactivity and release from a nanoparticle-loaded composite hydrogel. (2012) (89)
- The effects of intrathecal injection of a hyaluronan-based hydrogel on inflammation, scarring and neurobehavioural outcomes in a rat model of severe spinal cord injury associated with arachnoiditis. (2012) (89)
- Tuning the Microenvironment: Click‐Crosslinked Hyaluronic Acid‐Based Hydrogels Provide a Platform for Studying Breast Cancer Cell Invasion (2015) (88)
- Coil-reinforced hydrogel tubes promote nerve regeneration equivalent to that of nerve autografts. (2006) (86)
- Organic nanoscale drug carriers coupled with ligands for targeted drug delivery in cancer (2009) (86)
- Peripheral nerve regeneration through a synthetic hydrogel nerve tube. (2005) (85)
- Bioengineering Neural Stem/Progenitor Cell-Coated Tubes for Spinal Cord Injury Repair (2008) (83)
- Endothelial cells guided by immobilized gradients of vascular endothelial growth factor on porous collagen scaffolds. (2011) (83)
- PEG-Graft Density Controls Polymeric Nanoparticle Micelle Stability (2014) (80)
- Accelerated release of a sparingly soluble drug from an injectable hyaluronan-methylcellulose hydrogel. (2009) (78)
- Chitosan implants in the rat spinal cord: biocompatibility and biodegradation. (2011) (77)
- Two-photon micropatterning of amines within an agarose hydrogel (2008) (76)
- Functional immobilization of interferon-gamma induces neuronal differentiation of neural stem cells. (2009) (76)
- Effects of Dibutyryl Cyclic-AMP on Survival and Neuronal Differentiation of Neural Stem/Progenitor Cells Transplanted into Spinal Cord Injured Rats (2011) (76)
- The use of vascular endothelial growth factor functionalized agarose to guide pluripotent stem cell aggregates toward blood progenitor cells. (2010) (73)
- Hydrogel/electrospun fiber composites influence neural stem/progenitor cell fate (2010) (72)
- Characterization of hyaluronan-methylcellulose hydrogels for cell delivery to the injured spinal cord. (2013) (72)
- Complete spinal cord transection treated by implantation of a reinforced synthetic hydrogel channel results in syringomyelia and caudal migration of the rostral stump. (2006) (71)
- Delivery strategies for treatment of age-related ocular diseases: From a biological understanding to biomaterial solutions. (2015) (70)
- Cell delivery to the central nervous system. (2000) (70)
- Human Oligodendrogenic Neural Progenitor Cells Delivered with Chondroitinase ABC Facilitate Functional Repair of Chronic Spinal Cord Injury (2018) (69)
- In Vivo Bone Engineering in a Rabbit Femur (2003) (68)
- Three-dimensional spatial patterning of proteins in hydrogels. (2011) (68)
- A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke. (2013) (67)
- Anisotropic three-dimensional peptide channels guide neurite outgrowth within a biodegradable hydrogel matrix (2006) (66)
- Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain. (2015) (66)
- Mathematical model accurately predicts protein release from an affinity-based delivery system. (2015) (65)
- The adult retinal stem cell is a rare cell in the ciliary epithelium whose progeny can differentiate into photoreceptors (2011) (63)
- Peptide surface modification of poly(tetrafluoroethylene-co-hexafluoropropylene) enhances its interaction with central nervous system neurons. (1998) (62)
- A glial cell line-derived neurotrophic factor delivery system enhances nerve regeneration across acellular nerve allografts. (2016) (62)
- Axonal guidance channels in peripheral nerve regeneration (2004) (61)
- Poly(ethylene glycol) modification enhances penetration of fibroblast growth factor 2 to injured spinal cord tissue from an intrathecal delivery system. (2010) (61)
- Sustained delivery of bioactive neurotrophin-3 to the injured spinal cord. (2015) (61)
- Toward Spinal Cord Injury Repair Strategies: Peptide Surface Modification of Expanded Poly(Tetrafluoroethylene) Fibers for Guided Neurite Outgrowth In Vitro (2003) (61)
- Delayed implantation of intramedullary chitosan channels containing nerve grafts promotes extensive axonal regeneration after spinal cord injury. (2008) (61)
- Localized and Sustained Delivery of Fibroblast Growth Factor-2 from a Nanoparticle-Hydrogel Composite for Treatment of Spinal Cord Injury (2012) (61)
- Synthesis of Fluorocarbon-Vinyl Acetate Copolymers in Supercritical Carbon Dioxide: Insight into Bulk Properties (2002) (60)
- Chitosan Channels Containing Spinal Cord-Derived Stem/Progenitor Cells for Repair of Subacute Spinal Cord Injury in the Rat (2010) (60)
- Fibrin gels containing GDNF microspheres increase axonal regeneration after delayed peripheral nerve repair. (2013) (60)
- Click-crosslinked injectable hyaluronic acid hydrogel is safe and biocompatible in the intrathecal space for ultimate use in regenerative strategies of the injured spinal cord. (2015) (60)
- A novel polymeric drug delivery system for localized and sustained release of tacrolimus (FK506) (2015) (58)
- Independently Tuning the Biochemical and Mechanical Properties of 3D Hyaluronan-Based Hydrogels with Oxime and Diels-Alder Chemistry to Culture Breast Cancer Spheroids. (2017) (58)
- Effect of hyaluronic acid hydrogels containing astrocyte-derived extracellular matrix and/or V2a interneurons on histologic outcomes following spinal cord injury. (2018) (58)
- Novel Fluoro-Terpolymers for Coatings Applications (2005) (58)
- Experimental assessment of pro-lymphangiogenic growth factors in the treatment of post-surgical lymphedema following lymphadenectomy (2010) (57)
- Colloidal aggregation: from screening nuisance to formulation nuance. (2018) (56)
- Combination of a peptide-modified gellan gum hydrogel with cell therapy in a lumbar spinal cord injury animal model. (2016) (55)
- Neural stem/progenitor cells differentiate in vitro to neurons by the combined action of dibutyryl cAMP and interferon-gamma. (2009) (55)
- Polymers used to influence cell fate in 3D geometry: New trends (2012) (54)
- Novel intrathecal delivery system for treatment of spinal cord injury (2003) (53)
- Local delivery of chondroitinase ABC with or without stromal cell-derived factor 1α promotes functional repair in the injured rat spinal cord. (2017) (52)
- Modulation of bone marrow mesenchymal stem cell secretome by ECM-like hydrogels. (2013) (51)
- Poly(ethylene oxide)‐grafted thermoplastic membranes for use as cellular hybrid bio‐artificial organs in the central nervous system (1994) (50)
- Neural differentiation regulated by biomimetic surfaces presenting motifs of extracellular matrix proteins. (2009) (50)
- Thrombin mediated migration of osteogenic cells. (2005) (50)
- Creating porous tubes by centrifugal forces for soft tissue application. (2001) (48)
- Hydrogel for Simultaneous Tunable Growth Factor Delivery and Enhanced Viability of Encapsulated Cells in Vitro. (2016) (48)
- The role of endothelial cells in the retinal stem and progenitor cell niche within a 3D engineered hydrogel matrix. (2012) (48)
- Convenient syntheses of carboxylic acid functionalized fluoropolymer surfaces (1991) (47)
- Intrathecal drug delivery strategy is safe and efficacious for localized delivery to the spinal cord. (2007) (46)
- The use of immobilized neurotrophins to support neuron survival and guide nerve fiber growth in compartmentalized chambers. (2010) (46)
- Targeting HER2+ breast cancer cells: lysosomal accumulation of anti-HER2 antibodies is influenced by antibody binding site and conjugation to polymeric nanoparticles. (2013) (46)
- Self-Assembled Polymeric Nanoparticles of Organocatalytic Copolymerizated d,l-Lactide and 2-Methyl 2-Carboxytrimethylene Carbonate (2010) (45)
- Patterned poly(chlorotrifluoroethylene) guides primary nerve cell adhesion and neurite outgrowth. (2000) (44)
- Photo-immobilized EGF chemical gradients differentially impact breast cancer cell invasion and drug response in defined 3D hydrogels. (2018) (44)
- Controlled release strategy designed for intravitreal protein delivery to the retina (2019) (42)
- Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: a comparison of ectopic and orthotopic tumours (2012) (42)
- Synthesis and Solubility of Linear Poly(tetrafluoroethylene-co-vinyl acetate) in Dense CO2: Experimental and Molecular Modeling Results (2004) (42)
- GDNF released from microspheres enhances nerve regeneration after delayed repair (2012) (41)
- Polymer science for macroencapsulation of cells for central nervous system transplantation (1995) (41)
- Fabrication of Precise Cylindrical Three-Dimensional Tissue Engineering Scaffolds for In Vitro and In Vivo Bone Engineering Applications (2003) (40)
- Combined delivery of chondroitinase ABC and human induced pluripotent stem cell-derived neuroepithelial cells promote tissue repair in an animal model of spinal cord injury (2017) (40)
- Miniaturized system of neurotrophin patterning for guided regeneration (2008) (39)
- Transparent Porous Polysaccharide Cryogels Provide Biochemically Defined, Biomimetic Matrices for Tunable 3D Cell Culture (2016) (39)
- The Effect of Growth Factors and Soluble Nogo-66 Receptor Protein on Transplanted Neural Stem/Progenitor Survival and Axonal Regeneration after Complete Transection of Rat Spinal Cord (2012) (38)
- Antibody-Antisense Oligonucleotide Conjugate Downregulates a Key Gene in Glioblastoma Stem Cells (2018) (38)
- Biomaterials for neural-tissue engineering — Chitosan supports the survival, migration, and differentiation of adult-derived neural stem and progenitor cells (2010) (38)
- Functional motor recovery is improved due to local placement of GDNF microspheres after delayed nerve repair (2013) (38)
- Photoimmobilization of biomolecules within a 3-dimensional hydrogel matrix (2002) (37)
- In vitro sustained release of bioactive anti-NogoA, a molecule in clinical development for treatment of spinal cord injury. (2012) (37)
- Investigating the properties of novel poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) hydrogel hollow fiber membranes (2001) (37)
- Double click: dual functionalized polymeric micelles with antibodies and peptides. (2013) (37)
- Benchmarking to the Gold Standard: Hyaluronan‐Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture (2019) (36)
- Modular biodegradable biomaterials from surfactant and polyelectrolyte mixtures. (2008) (36)
- Amphiphilic micelles of poly(2-methyl-2-carboxytrimethylene carbonate-co-D,L-lactide)-graft-poly(ethylene glycol) for anti-cancer drug delivery to solid tumours. (2012) (36)
- Local delivery of FK506 to injured peripheral nerve enhances axon regeneration after surgical nerve repair in rats. (2019) (35)
- Stable Colloidal Drug Aggregates Catch and Release Active Enzymes. (2016) (35)
- Design of Protein‐Releasing Chitosan Channels (2008) (34)
- Surface Enrichment of Poly(trifluorovinyl ether)s in Polystyrene Blends (2000) (34)
- Rationally Designed 3D Hydrogels Model Invasive Lung Diseases Enabling High‐Content Drug Screening (2018) (34)
- Preclinical evaluation of taxane-binding peptide-modified polymeric micelles loaded with docetaxel in an orthotopic breast cancer mouse model. (2017) (34)
- Spinal cord blood flow and blood vessel permeability measured by dynamic computed tomography imaging in rats after localized delivery of fibroblast growth factor. (2010) (34)
- Strategies for Regeneration and Repair in the Injured Central Nervous System (2008) (34)
- A hyaluronan/methylcellulose-based hydrogel for local cell and biomolecule delivery to the central nervous system (2019) (33)
- Cyclosporin A enhances neural precursor cell survival in mice through a calcineurin-independent pathway (2014) (33)
- Designing Hydrogels for 3D Cell Culture Using Dynamic Covalent Crosslinking (2021) (32)
- Hyaluronic Acid‐Based Hydrogels Enable Rod Photoreceptor Survival and Maturation In Vitro through Activation of the mTOR Pathway (2016) (31)
- Local delivery of stabilized chondroitinase ABC degrades chondroitin sulfate proteoglycans in stroke‐injured rat brains (2019) (31)
- Local Delivery of Brain-Derived Neurotrophic Factor Enables Behavioral Recovery and Tissue Repair in Stroke-Injured Rats. (2019) (30)
- Injectable hydrogel enables local and sustained co-delivery to the brain: Two clinically approved biomolecules, cyclosporine and erythropoietin, accelerate functional recovery in rat model of stroke. (2020) (30)
- Furan-functionalized co-polymers for targeted drug delivery: caracterization, self-assembly and drug encapsulation (2008) (30)
- Tunable immunonanoparticle binding to cancer cells: thermodynamic analysis of targeted drug delivery vehicles (2009) (29)
- Assessing cognitive function following medial prefrontal stroke in the rat (2015) (29)
- Muscle stem cell intramuscular delivery within hyaluronan methylcellulose improves engraftment efficiency and dispersion. (2018) (29)
- Initial cell maturity changes following transplantation in a hyaluronan-based hydrogel and impacts therapeutic success in the stroke-injured rodent brain. (2019) (29)
- Synthesis of degradable poly(L-lactide-co-ethylene glycol) porous tubes by liquid-liquid centrifugal casting for use as nerve guidance channels. (2005) (29)
- Engineered polymeric nanoparticles to guide the cellular internalization and trafficking of small interfering ribonucleic acids (2017) (28)
- An engineered biocompatible drug delivery system enhances nerve regeneration after delayed repair. (2016) (28)
- Controlled release of bioactive PDGF-AA from a hydrogel/nanoparticle composite. (2015) (28)
- In Vitro Maturation of Human iPSC-Derived Neuroepithelial Cells Influences Transplant Survival in the Stroke-Injured Rat Brain. (2017) (28)
- Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival (2021) (28)
- Local Affinity Release. (2016) (27)
- Click conjugated polymeric immuno-nanoparticles for targeted siRNA and antisense oligonucleotide delivery. (2013) (27)
- Human Pluripotent Stem Cell-Derived TSC2-Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis. (2017) (26)
- Harnessing the Potential of Biomaterials for Brain Repair after Stroke (2018) (26)
- Transport of epidermal growth factor in the stroke-injured brain. (2011) (25)
- Local Delivery of Neurotrophin-3 and Anti-NogoA Promotes Repair After Spinal Cord Injury. (2016) (25)
- Biomaterials: surface interactions (2001) (24)
- Positron emission tomography imaging of fibrillar parenchymal and vascular amyloid-β in TgCRND8 mice. (2013) (23)
- Transplantation of porous tubes following spinal cord transection improves hindlimb function in the rat (2008) (23)
- Tissue mimetics: engineered hydrogel matrices provide biomimetic environments for cell growth. (2014) (23)
- Transplantation of Directly Reprogrammed Human Neural Precursor Cells Following Stroke Promotes Synaptogenesis and Functional Recovery (2019) (23)
- SPECTROSCOPIC CHARACTERIZATION OF POLYMER ADSORPTION AT THE AIR SOLUTION INTERFACE (1995) (23)
- Insight into the Surface Properties of Fluorocarbon-Vinyl Acetate Copolymer Films and Blends (2003) (22)
- In vivo biostability of a polymeric hollow fibre membrane for cell encapsulation. (1996) (22)
- Nonswelling, Ultralow Content Inverse Electron‐Demand Diels–Alder Hyaluronan Hydrogels with Tunable Gelation Time: Synthesis and In Vitro Evaluation (2020) (22)
- Internal Structure and Preferential Protein Binding of Colloidal Aggregates. (2017) (21)
- Synthesis and thermal stability of hybrid fluorosilicone polymers (2007) (21)
- Tissue engineered alternatives to nerve transplantation for repair of peripheral nervous system injuries. (2001) (21)
- Dynamic bioengineered hydrogels as scaffolds for advanced stem cell and organoid culture (2017) (20)
- Colloidal Drug Aggregate Stability in High Serum Conditions and Pharmacokinetic Consequence. (2019) (19)
- A New Spin on Antibody-Drug Conjugates: Trastuzumab-Fulvestrant Colloidal Drug Aggregates Target HER2-Positive Cells. (2017) (19)
- Enhancing the interaction of central nervous system neurons with poly(tetrafluoroethylene-co-hexafluoropropylene) via a novel surface amine-functionalization reaction followed by peptide modification. (1998) (19)
- Synthesis of Linear Poly(tetrafluoroethylene-co-vinyl acetate) in Carbon Dioxide (2000) (18)
- BONE MARROW CELL COLONIZATION OF, AND EXTRACELLULAR MATRIX EXPRESSION ON, BIODEGRADABLE POLYMERS (1997) (17)
- Inverse Electron-Demand Diels-Alder Methylcellulose Hydrogels Enable the Co-Delivery of Chondroitinase ABC and Neural Progenitor Cells. (2020) (16)
- Anti-Amyloid-β-Mediated Positron Emission Tomography Imaging in Alzheimer's Disease Mouse Brains (2012) (16)
- 6-Bromo-7-hydroxy-3-methylcoumarin (mBhc) is an efficient multi-photon labile protecting group for thiol caging and three-dimensional chemical patterning. (2016) (16)
- Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute. (2021) (16)
- Design considerations of polymeric nanoparticle micelles for chemotherapeutic delivery (2013) (16)
- Targeting the amyloid-β antibody in the brain tissue of a mouse model of Alzheimer's disease. (2012) (15)
- Endogenous radial glial cells support regenerating axons after spinal cord transection (2010) (15)
- Polymer Surface Modification (1995) (15)
- A quantitative ELISA for bioactive anti-Nogo-A, a promising regenerative molecule for spinal cord injury repair. (2009) (14)
- de Doxorubicin-Conjugated Immuno-Nanoparticles for Intracellular Anticancer Drug Delivery P E R (2009) (14)
- Effect of Sugar 2′,4′-Modifications on Gene Silencing Activity of siRNA Duplexes (2019) (14)
- Hydrogel-mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration. (2020) (14)
- An Injectable Hyaluronan–Methylcellulose (HAMC) Hydrogel Combined with Wharton’s Jelly-Derived Mesenchymal Stromal Cells (WJ-MSCs) Promotes Degenerative Disc Repair (2020) (14)
- Cationic block amphiphiles show anti-mitochondrial activity in multi-drug resistant breast cancer cells. (2019) (14)
- Leveraging Colloidal Aggregation for Drug-Rich Nanoparticle Formulations. (2017) (13)
- Modeling of Photoreceptor Donor‐Host Interaction Following Transplantation Reveals a Role for Crx, Müller Glia, and Rho/ROCK Signaling in Neurite Outgrowth (2019) (12)
- Modulated Protein Delivery to Engineer Tissue Repair. (2019) (12)
- Core and Corona Modifications for the Design of Polymeric Micelle Drug-Delivery Systems (2013) (12)
- The use of polymers in the treatment of neurological disorders (1995) (12)
- Synthesis of Trifluorovinyl Ethers Incorporating Functionalized Hydrocarbon Ether Groups: Insight into the Mechanism of Trifluorovinyl Ether Formation from Trimethylsilyl 2-Alkoxy-2,3,3,3-tetrafluoropropionates (1997) (11)
- Designer Biomaterials to Model Cancer Cell Invasion In Vitro: Predictive Tools or Just Pretty Pictures? (2020) (11)
- Defining the Surface Chemistry of Ammonia-Modified Poly(tetrafluoroethylene-co-hexafluoropropylene) Films (1999) (10)
- Innovative use of the taxol binding peptide overcomes key challenges of stable and high drug loading in polymeric nanomicelles. (2015) (10)
- Synthesis and characterization of novel polysiloxane-grafted fluoropolymers (2005) (9)
- Adult skin-derived precursor Schwann cell grafts form growths in the injured spinal cord of Fischer rats (2018) (9)
- Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells. (2018) (9)
- Nanoparticle delivery of a pH-sensitive prodrug of doxorubicin and a mitochondrial targeting VES-H8R8 synergistically kill multi-drug resistant breast cancer cells (2020) (9)
- Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability (2020) (9)
- Polymers for Tissue Engineering (2011) (8)
- Influencing neuroplasticity in stroke treatment with advanced biomaterials-based approaches. (2019) (8)
- In vitro Evaluation of ASCs and HUVECs Co-cultures in 3D Biodegradable Hydrogels on Neurite Outgrowth and Vascular Organization (2020) (7)
- Attenuated diphtheria toxin mediates siRNA delivery (2020) (7)
- The role of biomaterials in overcoming barriers to regeneration in the central nervous system (2018) (7)
- Biomaterials driving repair after stroke (2018) (7)
- Radical copolymerization of novel trifluorovinyl ethers with ethyl vinyl ether and vinyl acetate : Estimating reactivity ratios and understanding reactivity behavior of the propagating radical (2000) (7)
- Chapter 55 – Central Nervous System (2011) (6)
- Control of wettability of polymers using organic surface chemistry (1992) (5)
- Triggered Release Enhances the Cytotoxicity of Stable Colloidal Drug Aggregates. (2019) (5)
- Surface modification of poly(tetrafluoroethylene-co-hexafluoropropylene) film by adsorption of poly(L-lysine) from aqueous solution (1991) (5)
- Single-cell chromatin accessibility in glioblastoma delineates cancer stem cell heterogeneity predictive of survival (2018) (5)
- Recent advances in regenerative medicine approaches for spinal cord injuries (2017) (5)
- Author response: A 3D culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction (2019) (5)
- Naturally-derived and bioinspired materials. (2015) (4)
- Wielding the Double‐Edged Sword of Inflammation: Building Biomaterial‐Based Strategies for Immunomodulation in Ischemic Stroke Treatment (2021) (4)
- Polymerization of novel trifluorovinyl ethers: Insight into the mechanisms of termination and chain transfer (1999) (4)
- A three-dimensional culture model of innervated human skeletal muscle enables studies of the adult neuromuscular junction and disease modeling (2018) (4)
- Attenuated diphtheria toxin mediates siRNA delivery (2020) (4)
- Chemically and mechanically defined hyaluronan hydrogels emulate the extracellular matrix for unbiased in vivo and in vitro organoid formation and drug testing in cancer (2022) (4)
- Gelatin‐Hyaluronan Click‐Crosslinked Cryogels Elucidate Human Macrophage Invasion Behavior (2021) (4)
- Photochemically Activated Notch Signaling Hydrogel Preferentially Differentiates Human Derived Hepatoblasts to Cholangiocytes (2020) (4)
- 9 – Peptide modification of polysaccharide scaffolds for targeted cell signaling (2008) (4)
- Insights into the Properties of Novel Trifluorovinyl Ether Copolymers1 (1999) (3)
- Synthesis of an Enzyme-Mediated Reversible Cross-linked Hydrogel for Cell Culture. (2021) (3)
- COMPLETE SPINAL CORD TRANSECTION TREATEDBY IMPLANTATION OF A REINFORCED SYNTHETIC HYDROGEL CHANNEL RESULTS IN SYRINGOMYELIA AND CAUDAL MIGRATION OF THE ROSTRAL STUMP (2006) (3)
- Cyclosporine-immunosuppression does not affect survival of transplanted skin-derived precursor Schwann cells in the injured rat spinal cord (2017) (3)
- Controlling modulus and morphology of hydrogel tubes through surface modification (2004) (3)
- ECM‐Inspired Chemical Cues: Biomimetic Molecules and Techniques of Immobilization (2014) (3)
- Appearance of Focal Liver Lesions Using Contrast-Enhanced Magnetic Resonance Imaging Using Gadofosveset Trisodium, an Intravascular (Blood-Pool) Contrast Agent: A Pictorial Essay (2016) (3)
- Reengineering biocatalysts: Computational redesign of chondroitinase ABC improves efficacy and stability. (2020) (3)
- Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. (2017) (2)
- Chitosan supports the survival , migration , and differentiation of adult-derived neural stem and progenitor cells (2010) (2)
- Biometerials for Brain Tissue Engineering (2010) (2)
- A ffi nity-Based Drug Delivery Systems for Tissue Repair and Regeneration (2014) (2)
- 73 – Tissue Therapy: Central Nervous System (2008) (2)
- Chapter 30 – Central Nervous System (2015) (2)
- Tissue Engineering Strategies for Axonal Regeneration Following Spinal Cord Injury (2002) (2)
- Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. (2017) (1)
- Abstract 25: Enhancement of Nerve Regeneration after Delayed Repair with Controlled Release of Neurotrophic Factors. (2015) (1)
- In vivo drug release, functional recovery and tissue repair in stroke-injured rats after local delivery of cyclosporine and erythropoietin from epi-cortically implanted hyaluronan and methylcellulose (HAMC) hydrogel (2020) (1)
- Anticancer Drug Delivery: Doxorubicin‐Conjugated Immuno‐Nanoparticles for Intracellular Anticancer Drug Delivery (Adv. Funct. Mater. 11/2009) (2009) (1)
- ARTICLES: FORMULATION AND ENGINEERING OF BIOMATERIALS Design of Protein-Releasing Chitosan Channels (2008) (1)
- Directed Evolution Enables Simultaneous Controlled Release of Multiple Therapeutic Proteins from Biopolymer‐Based Hydrogels (2022) (1)
- Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: a comparison of ectopic and orthotopic tumours (2012) (1)
- Synthesis of Trifluorovinyl Ethers Incorporating Functionalized Hydrocarbon Ether Groups: Insight into the Mechanism of Trifluorovinyl Ether Formation from Trimethylsilyl 2‐Alkoxy‐2,3,3,3‐tetrafluoropropionates. (1998) (1)
- A Bioengineered Delivery System For The Transplantation Of Mouse Retinal Stem Cell-derived Rod Photoreceptors Encourages Cell Survival And Integration (2012) (1)
- Af fi nity-based release of chondroitinase ABC from a modi fi ed methylcellulose hydrogel (2013) (1)
- Temporally Controlled Photouncaged Epidermal Growth Factor Influences Cell Fate in Hydrogels. (2021) (1)
- Biomaterials: drug delivery systems (2002) (1)
- Investigating a new entubulation strategy to overcome peripheral nerve injury (1999) (1)
- Positron Emission Tomography Imaging of Fibrillar Parenchymal and Vascular Amyloid ‐ β in TgCRND 8 Mice (2013) (1)
- Three Dimensional Hydrogel Scaffolds and Applications in the CNS (2015) (1)
- Tunable Surface Charge Enables the Electrostatic Adsorption-Controlled Release of Neuroprotective Peptides from a Hydrogel-Nanoparticle Drug Delivery System. (2022) (1)
- Glial-derived neurotrophic factor (GDNF) delivered from microspheres enhances peripheral nerve regeneration after delayed nerve repair (2012) (1)
- Combined Cell and Gene Therapy towards the Treatment of Age-Related Macular Degeneration and Diabetic Retinopathy (2016) (1)
- Scaffolds for Tissue Engineering Clinical Use of Porous Scaffolds for Tissue Engineering of Skin (1)
- Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine. (2017) (1)
- Processing of Polymer Scaffolds (2002) (1)
- Co-transplantation of RPE and photoreceptors rescues vision in a mouse model of advanced retinal degeneration (2018) (0)
- Membrane of an acrylonitrile polymer (1994) (0)
- Poly ( ethy 1 ene oxide )-Grafted Thermoplastic Membranes for Use as Cellular Hybrid Bio-Artificial Organs in the Central Nervous System (2003) (0)
- Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury (2019) (0)
- Membrane formed by a polymer based on acrylonitrile. (1994) (0)
- An interview with Molly S Shoichet. Developing biomaterials and mobilizing resources for assaults on some of the most devastating medical problems by Myron Spector. (2013) (0)
- Editorial for Virtual Issue on Polymer Bioconjugates in Biology and Medicine (2017) (0)
- Synthetic Ionizable Colloidal Drug Aggregates Enable Endosomal Disruption (2023) (0)
- The membranes formed from an acrylonitrile-based polymer (1994) (0)
- Hyaluronic acid-based hydrogels enhance isolated rod photoreceptor survival in vitro through mTOR activation (2016) (0)
- Guiding PC12 cell neurite outgrowth by a homogenous NGF concentration gradient (1999) (0)
- Reply to Comment on ‘Adult skin-derived precursor Schwann cell grafts form growths in the injured spinal cord of Fischer rats’ (2018) (0)
- Three-dimensional drug screen identifies HDAC inhibitors as therapeutic agents in mTORC1-driven lymphangioleiomyomatosis (2021) (0)
- Abstract 6316: High throughput small molecule screening with synthetic 3D lung-mimetic hydrogels in the rare lung cancer lymphangioleiomyomatosis (2020) (0)
- FUNCTIONAL RECOVERY FOLLOWING SPINAL CORD HEMISECTION MEDIATED BY A UNIQUE POLYMER SCAFFOLD SEEDED WITH NEURAL STEM CELLS (2000) (0)
- Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels. (2023) (0)
- TRANSLATIONAL IMPACT Clinical issue The development of stem cell-based therapies for the treatment of trauma or disease is an exciting prospect in regenerative medicine (2014) (0)
- Investigating strategies to enhance axonal regeneration in the CNS (1999) (0)
- An in-vitro retina aggregate system to investigate the effects of environment on photoreceptor neurite outgrowth (2019) (0)
- Induction of rod and cone photoreceptor-specific progenitors from retinal stem cells (2018) (0)
- Viscoelastic Notch Signaling Hydrogel Induces Liver Bile Duct Organoid Growth and Morphogenesis (2022) (0)
- Process for fabrication of structures by use of centrifugal forces (2001) (0)
- Exogenous factors induce rod and cone photoreceptor-specific progenitors from adult mouse retinal stem cells (2015) (0)
- 166: DEVELOPMENT OF A MICROSPHERE DRUG DELIVERY SYSTEM TO PROMOTE NERVE REGENERATION AFTER PERIPHERAL NERVE INJURY (2011) (0)
- A Composite Methylcellulose Hydrogel for Controlled Release of Multiple Therapeutics to the Injured Spinal Cord (2014) (0)
- Development of a Stem Cell Delivery System to Treat Retinal Degenerative Diseases (2010) (0)
- 7.31 Biomaterials for Spinal Cord Repair (2017) (0)
- Engineered safe and immune-tolerant ‘designer’ rpe cells towards the treatment of age-related macular degeneration (2021) (0)
- Bioengineering Strategies to Control Neural Stem/Progenitor Cell Differentiation (2009) (0)
- Bioengineered and Regenerative Medicine Strategies for Retina Repair (2018) (0)
- Abstract 127: Sustained Release of FK506 from a Polymeric Drug Delivery System for the Treatment of Peripheral Nerve Injury. (2015) (0)
- Author response: Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival (2021) (0)
- Investigating the impact of cell maturity on transplantation success for CNS injury (2020) (0)
- Transplantation of Directly Reprogrammed Human Neural Precursor Cells Following Stroke Promotes Synaptogenesis and Functional Recovery (2019) (0)
- Muscle stem cell intramuscular delivery within hyaluronan methylcellulose improves engraftment efficiency and dispersion (2018) (0)
- Affibody-mediated controlled release of fibroblast growth factor 2. (2022) (0)
- Hydrogel assisted photoreceptor delivery inhibits material transfer (2023) (0)
- Looking Back: Disease Modeling. (2017) (0)
- Axonal Guidance Channels in Peripheral Nerve Regeneration Peripheral Nerve Injury and Repair (0)
- Induction of Rod and Cone Photoreceptor-Specific Progenitors from Stem Cells. (2019) (0)
- Efficacy of Transplant and Endogenous Precursor and Stem Cell Interventions on Stroke Recovery: A Critical Assessment (2013) (0)
- DELAYED IMPLANTATION OF INTRAMEDULLARY CHITOSAN CHANNELS CONTAINING NERVE GRAFTS PROMOTES EXTENSIVE AXONAL REGENERATION AFTER SPINAL CORD INJURY (2008) (0)
- Prospective Evaluation of Outcomes in Migraine Surgery Patients at the Massachusetts General Hospital (2016) (0)
- Synthesis and characterization of novel polysiloxane-grafted fluoropolymers 1 (2005) (0)
- Syntheses of Carboxylic Acid Functionalized Fluoropolymer Surfaces 1 (2001) (0)
- Poly(L-Lysine) Adsorption to Fluoropolymer Films (1990) (0)
- Human Macrophage Invasion: Gelatin‐Hyaluronan Click‐Crosslinked Cryogels Elucidate Human Macrophage Invasion Behavior (Adv. Funct. Mater. 28/2021) (2021) (0)
- aryl nitrile-based polymer formed by the membrane (1995) (0)
- Protein Release by Controlled Desorption from Transiently Cationic Nanoparticles. (2023) (0)
- Cationic nanoparticles for biomedical applications (2020) (0)
- Affinity-Controlled Release of Rod-derived Cone Viability Factor Enhances Cone Photoreceptor Survival. (2023) (0)
- Biomaterials for Spinal Cord Repair (2011) (0)
- Synthesis and adsorption of polymers :: control of polymer and surface structure/ (1992) (0)
- Contents lists available at ScienceDirect (2015) (0)
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