Nancy Rothwell
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British physiologist, medical researcher and academic, (1955– ), England, UK
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Why Is Nancy Rothwell Influential?
(Suggest an Edit or Addition)Areas of Specialization: Physiology
Nancy Rothwell is the President and Vice-Chancellor of the University of Manchester, the director of AstraZeneca, a global pharmaceuticals company, and a physiologist. She is also a trustee of Cancer Research UK and chair of the Research Defence Society. She earned her first class degree in physiology and a PhD from Queen Elizabeth College.
Her early research efforts were focused on obesity, cachexia, and energy balance regulation. She is a vocal supporter of women in science and has provided visionary leadership in her roles as the president of the Royal Society of Biology. She was the first woman to lead the University of Manchester, a testament to her groundbreaking work and transformative leadership style.
Rothwell was named Dame Commander of the Order of the British Empire and is a fellow of the Royal Society, the Royal Society of Biology and the Academy of Medical Sciences. She was named one of the most powerful women in the United Kingdom by Women’s Hour and received the Royal Society Pfizer Award.
Most recently, she has been researching the role of inflammation in brain disease. Her discovery of the impacts of cytokine interleukin-1 is giving rise to new treatment methods designed to inhibit the inflammatory response in strokes.
Featured in Top Influential Biologists Today and Top Women in STEM
According to Wikipedia, Dame Nancy Jane Rothwell is a British physiologist. She has served as president and vice-chancellor of the University of Manchester since July 2010, having served as Deputy President and Deputy Vice-Chancellor until January 2010.
Nancy Rothwell's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- A role for brown adipose tissue in diet-induced thermogenesis (1979) (1251)
- The role of inflammation in CNS injury and disease (2006) (1224)
- Interleukin-1 and neuronal injury (2005) (942)
- Cytokines and the nervous system II: actions and mechanisms of action (1995) (938)
- Cytokines and the nervous system I: expression and recognition (1995) (816)
- Cytokines and acute neurodegeneration (1997) (728)
- Interleukin 1 in the brain: biology, pathology and therapeutic target (2000) (685)
- Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat (1992) (584)
- Cleavage of the Plasma Membrane Na+/Ca2+ Exchanger in Excitotoxicity (2005) (556)
- Cytokines and acute neurodegeneration (2001) (473)
- Neuroprotective Effects of Human Recombinant Interleukin-1 Receptor Antagonist in Focal Cerebral Ischaemia in the Rat (1996) (466)
- Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome (2004) (464)
- Cerebral Interleukin-6 is Neuroprotective during Permanent Focal Cerebral Ischemia in the Rat (1998) (414)
- A role for brown adipose tissue in diet-induced thermogenesis. (1997) (398)
- Leptin actions on food intake and body temperature are mediated by IL-1. (1999) (372)
- Effect of diet and cold exposure on norepinephrine turnover in brown adipose tissue of the rat. (1982) (342)
- Systemic Inflammatory Stimulus Potentiates the Acute Phase and CXC Chemokine Responses to Experimental Stroke and Exacerbates Brain Damage via Interleukin-1- and Neutrophil-Dependent Mechanisms (2007) (337)
- Diet-induced thermogenesis. (1983) (327)
- Activation of brown adipose tissue thermogenesis by the ventromedial hypothalamus (1981) (318)
- Inflammation in central nervous system injury. (2003) (315)
- Different receptor mechanisms mediate the pyrogenic and behavioral effects of interleukin 1. (1992) (313)
- Systemic infection, inflammation and acute ischemic stroke (2009) (307)
- Systemic Inflammation Alters the Kinetics of Cerebrovascular Tight Junction Disruption after Experimental Stroke in Mice (2008) (298)
- Cytokines and fever. (1996) (294)
- Role of IL-1α and IL-1β in Ischemic Brain Damage (2001) (291)
- An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis (2003) (290)
- Interleukin-1 and neuronal injury: mechanisms, modification, and therapeutic potential (2003) (286)
- Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation (2010) (282)
- Chronic effects of β2 agonists on body composition and protein synthesis in the rat (1984) (269)
- The role of interleukin 1 in acute neurodegeneration and stroke: pathophysiological and therapeutic implications. (1997) (267)
- Caspase-1-dependent processing of pro-interleukin-1β is cytosolic and precedes cell death (2007) (255)
- The Progression and Topographic Distribution of Interleukin-1β Expression after Permanent Middle Cerebral Artery Occlusion in the Rat (1999) (253)
- Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat (1995) (251)
- Improving Outcome after Stroke: Overcoming the Translational Roadblock (2008) (248)
- Cytokines ‐ killers in the brain? (1999) (245)
- Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology. (1996) (244)
- Potential mechanisms of interleukin-1 involvement in cerebral ischaemia (1999) (242)
- Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. (1983) (234)
- Salbutamol, a beta 2-adrenoceptor agonist, increases skeletal muscle strength in young men. (1992) (233)
- Interleukin-1 and inflammatory neurodegeneration. (2007) (228)
- Circulating interleukin‐6 mediates the febrile response to localised inflammation in rats (2000) (226)
- An ICE inhibitor, z-VAD-DCB attenuates ischaemic brain damage in the rat. (1996) (212)
- A dual role for interleukin-1 in LTP in mouse hippocampal slices (2003) (201)
- Priming of Macrophages with Lipopolysaccharide Potentiates P2X7-mediated Cell Death via a Caspase-1-dependent Mechanism, Independently of Cytokine Production* (2002) (200)
- Central effects of CRF on metabolism and energy balance (1990) (197)
- Brain inflammation is induced by co-morbidities and risk factors for stroke (2011) (189)
- Delayed administration of interleukin‐1 receptor antagonist protects against transient cerebral ischaemia in the rat (2003) (188)
- AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3 (2015) (186)
- Endogenous Interleukin-1 Receptor Antagonist Mediates Anti-Inflammatory and Neuroprotective Actions of Cannabinoids in Neurons and Glia (2003) (185)
- Excitotoxic brain damage in the rat induces interleukin‐1β protein in microglia and astrocytes: Correlation with the progression of cell death (1999) (184)
- The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial (2014) (179)
- Neutrophil Cerebrovascular Transmigration Triggers Rapid Neurotoxicity through Release of Proteases Associated with Decondensed DNA (2012) (175)
- Regulation of energy balance in two models of reversible obesity in the rat. (1979) (172)
- Interleukin‐1β and the interleukin‐1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat (1998) (171)
- Platelet interleukin-1alpha drives cerebrovascular inflammation. (2010) (169)
- Extracellular ATP and P2X7 receptors in neurodegeneration. (2002) (168)
- Expression of interleukin‐1 receptors and their role in interleukin‐1 actions in murine microglial cells (2002) (168)
- Involvement of cytokines in acute neurodegeneration in the CNS (1993) (167)
- Cytokines in neurodegeneration and repair (1995) (166)
- Anabolic effects of clenbuterol on skeletal muscle are mediated by beta 2-adrenoceptor activation. (1992) (164)
- Tumor Necrosis Factor α Is a Critical Component of Interleukin 13–Mediated Protective T Helper Cell Type 2 Responses during Helminth Infection (1999) (163)
- Inflammation in Human Brain Injury: Intracerebral Concentrations of IL-1α, IL-1β, and Their Endogenous Inhibitor IL-1ra (2007) (156)
- Interleukin-6 is a centrally acting endogenous pyrogen in the rat. (1991) (156)
- Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat. (1996) (154)
- Similarities between cold- and diet-induced thermogenesis in the rat (1980) (151)
- Interleukin-1 Influences Ischemic Brain Damage in the Mouse Independently of the Interleukin-1 Type I Receptor (2002) (148)
- Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro (2017) (146)
- Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesis (1980) (145)
- Ca2+ Stores and Ca2+ Entry Differentially Contribute to the Release of IL-1β and IL-1α from Murine Macrophages1 (2003) (144)
- Endogenous interleukin-1 receptor antagonist is neuroprotective. (1997) (142)
- CRF is involved in the pyrogenic and thermogenic effects of interleukin 1 beta in the rat. (1989) (139)
- A role for insulin in the diet-induced thermogenesis of cafeteria-fed rats. (1981) (138)
- Purinergic (P2X7) Receptor Activation of Microglia Induces Cell Death via an Interleukin-1-Independent Mechanism (2002) (136)
- Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide‐induced nitric oxide release in astrocyte cultures (2002) (135)
- Microglia and Macrophages Differentially Modulate Cell Death After Brain Injury Caused by Oxygen-Glucose Deprivation in Organotypic Brain Slices (2013) (135)
- Lipocortin-1 is an endogenous inhibitor of ischemic damage in the rat brain (1991) (133)
- Delayed Administration of Interleukin-1 Receptor Antagonist Reduces Ischemic Brain Damage and Inflammation in Comorbid Rats (2012) (130)
- Role of P2X7 Receptors in Ischemic and Excitotoxic Brain Injury In Vivo (2003) (130)
- A Rapid and Transient Peripheral Inflammatory Response Precedes Brain Inflammation after Experimental Stroke (2009) (129)
- Chronic Systemic Infection Exacerbates Ischemic Brain Damage via a CCL5 (Regulated on Activation, Normal T-Cell Expressed and Secreted)-Mediated Proinflammatory Response in Mice (2010) (128)
- Caspases Mediate 6‐Hydroxydopamine‐Induced Apoptosis but Not Necrosis in PC12 Cells (1998) (128)
- Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro (2012) (127)
- Effect of dietary fish oil supplementation on fever and cytokine production in human volunteers. (1993) (127)
- NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1 (2007) (126)
- Regulation of energy balance. (1981) (121)
- Activation of brown fat thermogenesis in response to central injection of corticotropin releasing hormone in the rat (1987) (119)
- Release of Interleukin-1α or Interleukin-1β Depends on Mechanism of Cell Death* (2014) (117)
- Neuroprotective actions of endogenous interleukin‐1 receptor antagonist (IL‐1ra) are mediated by glia (2006) (115)
- SCIL-STROKE (Subcutaneous Interleukin-1 Receptor Antagonist in Ischemic Stroke): A Randomized Controlled Phase 2 Trial (2018) (112)
- Pyrogenic and thermogenic effects of interleukin 1 beta in the rat. (1989) (110)
- Involvement of interleukin-1 and lipocortin-1 in ischaemic brain damage. (1993) (110)
- Local cytokine induction by LPS in the rat air pouch and its relationship to the febrile response. (1997) (109)
- Febrile response to tissue inflammation involves both peripheral and brain IL-1 and TNF-alpha in the rat. (1997) (108)
- Mechanisms of thermogenesis induced by low protein diets. (1983) (108)
- PRL-releasing peptide interacts with leptin to reduce food intake and body weight. (2002) (107)
- Interleukin-1 Receptor Antagonist Penetrates Human Brain at Experimentally Therapeutic Concentrations (2008) (105)
- An Integrated Analysis of the Progression of Cell Responses Induced by Permanent Focal Middle Cerebral Artery Occlusion in the Rat (1998) (105)
- CNS regulation of thermogenesis. (1994) (104)
- Energy balance, diet-induced thermogenesis and brown adipose tissue in lean and obese (fa/fa) Zucker rats after adrenalectomy. (1983) (104)
- Leptin affects food intake via CRF-receptor-mediated pathways (1998) (101)
- Biological activity and brain actions of recombinant rat interleukin-1alpha and interleukin-1beta. (1998) (100)
- Interleukin-1 receptor antagonist is beneficial after subarachnoid haemorrhage in rat by blocking haem-driven inflammatory pathology (2012) (100)
- Interleukin-1 and Stroke: Biomarker, Harbinger of Damage, and Therapeutic Target (2011) (99)
- Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study (2010) (98)
- Inflammation in human brain injury: intracerebral concentrations of IL-1alpha, IL-1beta, and their endogenous inhibitor IL-1ra. (2007) (98)
- Involvement of corticotrophin releasing factor (CRF) in the thermogenic and anorexic actions of serotonin (5-HT) and related compounds (1991) (98)
- The role of brown adipose tissue in diet-induced thermogenesis (1989) (97)
- Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage (2012) (95)
- Effects of feeding a "cafeteria" diet on energy balance and diet-induced thermogenesis in four strains of rat. (1982) (94)
- Effects of feeding a palatable ‘cafeteria’ diet on energy balance in young and adult lean (+/?) Zucker rats (1982) (92)
- Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebral ischaemia or activation of NMDA receptors in the rat brain (1994) (92)
- Central administration of rat IL-6 induces HPA activation and fever but not sickness behavior in rats. (1999) (92)
- Cloning of rat brain interleukin-18 cDNA (1998) (90)
- Annual review prize lecture cytokines - killers in the brain? (1999) (90)
- Anorexic But Not Pyrogenic Actions of Interleukin‐1 are Modulated by Central Melanocortin‐3/4 Receptors in the Rat (2001) (89)
- Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat. (2000) (88)
- Leptin induces interleukin‐1β release from rat microglial cells through a caspase 1 independent mechanism (2007) (83)
- Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production (2007) (82)
- Interleukin-1 in Stroke: From Bench to Bedside. (2016) (80)
- Changes in tissue blood flow and β‐receptor density of skeletal muscle in rats treated with the β2‐adrenoceptor agonist clenbuterol (1987) (80)
- [18F]DPA-714: Direct Comparison with [11C]PK11195 in a Model of Cerebral Ischemia in Rats (2013) (80)
- Inhibition of central actions of cytokines on fever and thermogenesis by lipocortin-1 involves CRF. (1992) (80)
- Energy expenditure of ‘cafeteria’‐fed rats determined from measurements of energy balance and indirect calorimetry. (1982) (79)
- Sympathetic activation of brown-adipose-tissue thermogenesis in cachexia (1981) (79)
- Energy balance and mitochondrial function in liver and brown fat of rats fed "cafeteria" diets of varying protein content. (1982) (78)
- Pharmacology of interleukin-1 actions in the brain. (1994) (78)
- CNS injury: the role of the cytokine IL-1. (2004) (77)
- Neuroprotective effects of the synthetic cannabinoid HU-210 in primary cortical neurons are mediated by phosphatidylinositol 3-kinase/AKT signaling (2005) (77)
- Central activation of thermogenesis and fever by interleukin-1β and interleukin-1α involves different mechanisms (1989) (75)
- The Acute-Phase Protein PTX3 is an Essential Mediator of Glial Scar Formation and Resolution of Brain Edema after Ischemic Injury (2014) (75)
- Tumor necrosis factor-alpha and fever after peripheral inflammation in the rat. (1994) (75)
- Influence of carbohydrate and fat intake on diet-induced thermogenesis and brown fat activity in rats fed low protein diets. (1987) (73)
- Variability of the systemic acute phase response after ischemic stroke (2006) (73)
- Effects of manipulating dietary protein and energy intake on energy balance and thermogenesis in the pig. (1980) (72)
- Effects of denervating brown adipose tissue on the responses to cold, hyperphagia and noradrenaline treatment in the rat. (1984) (71)
- Hypothalamic control of feeding (1999) (70)
- Effect of diet and fenfluramine on thermogenesis in the rat: possible involvement of serotonergic mechanisms. (1987) (70)
- Reduction of inflammation after administration of interleukin-1 receptor antagonist following aneurysmal subarachnoid hemorrhage: results of the Subcutaneous Interleukin-1Ra in SAH (SCIL-SAH) study. (2017) (69)
- Boron-Based Inhibitors of the NLRP3 Inflammasome (2017) (69)
- Ca2+ stores and Ca2+ entry differentially contribute to the release of IL-1 beta and IL-1 alpha from murine macrophages. (2003) (68)
- The cafeteria diet as a tool for studies of thermogenesis. (1988) (67)
- Efficient discovery of anti-inflammatory small molecule combinations using evolutionary computing (2011) (67)
- Central effects of TNFα on thermogenesis and fever in the rat (1988) (66)
- Thermogenic effects of the antiglucocorticoid RU-486 in the rat: involvement of corticotropin-releasing factor and sympathetic activation of brown adipose tissue. (1989) (66)
- Multiple mechanisms mediate antipyretic action of glucocorticoids. (1995) (65)
- Increased Brain Microvascular MMP-9 and Incidence of Haemorrhagic Transformation in Obese Mice after Experimental Stroke (2010) (65)
- Systemic inflammation and stroke: aetiology, pathology and targets for therapy. (2007) (65)
- Experimental Stroke-Induced Changes in the Bone Marrow Reveal Complex Regulation of Leukocyte Responses (2011) (64)
- The effect of high fat and high carbohydrate cafeteria diets on diet-induced thermogenesis in the rat. (1983) (64)
- A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke (2015) (63)
- Effects of age on diet-induced thermogenesis and brown adipose tissue metabolism in the rat. (1983) (62)
- Eicosanoids, thermogenesis and thermoregulation. (1992) (62)
- A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat (2007) (60)
- Detection of the interleukin 18 family in rat brain by RT-PCR. (2000) (60)
- Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus‐dependent (2002) (59)
- Diet-induced thermogenesis. (1982) (59)
- Lipocortin 1 fragment modifies pyrogenic actions of cytokines in rats. (1990) (59)
- Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage. (2008) (59)
- Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia (2017) (58)
- Biological distribution and significance of brown adipose tissue. (1985) (57)
- Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity (2008) (57)
- Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection (2012) (57)
- Mechanisms of the pyrogenic actions of cytokines. (1990) (56)
- Changes in thermogenesis and brown fat activity in response to tumour necrosis factor in the rat (1987) (55)
- Mofification of body composition by clenbuterol in normal and dystrophic (mdx) mice (1985) (54)
- Mechanisms of tumor necrosis factor alpha action on neurodegeneration: interaction with insulin-like growth factor-1. (1999) (54)
- Decerebration activates thermogenesis in the rat. (1983) (53)
- The role of lipocortin‐1 in dexamethasone‐induced suppression of PGE2 and TNFα release from human peripheral blood mononuclear cells (1996) (52)
- Pannexin-1-dependent caspase-1 activation and secretion of IL-1β is regulated by zinc (2009) (52)
- Lipocortin-1 inhibits NMDA receptor-mediated neuronal damage in the striatum of the rat (1992) (51)
- Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression. (2012) (51)
- Insulin and thermogenesis. (1988) (51)
- Brown fat, thermogenesis and physiological birth in a marsupial. (1985) (51)
- Localization of immunoreactive lipocortin-1 in the brain and pituitary gland of the rat. Effects of adrenalectomy, dexamethasone and colchicine treatment (1991) (51)
- Effects of diet and acute noradrenaline treatment on brown adipose tissue development and mitochondrial purine-nucleotide binding. (1982) (50)
- Cytokines in the Nervous System (1996) (50)
- Energy balance and brown fat activity in rats fed cafeteria diets or high-fat, semisynthetic diets at several levels of intake. (1985) (50)
- Mechanisms of activation of the pituitary-adrenal axis by tissue injury in the rat (1994) (49)
- The role of TNF‐α in fever: opposing actions of human and murine TNF‐α and interactions with IL‐β in the rat (1996) (48)
- Brain TNF: Damage limitation or damaged reputation? (1996) (48)
- IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient mice. (2002) (48)
- Stimulation of thermogenesis and brown fat activity in rats fed medium chain triglyceride. (1987) (47)
- Interleukins and cerebral ischaemia. (1997) (47)
- No Role for Interleukin-18 in Acute Murine Stroke-Induced Brain Injury (2003) (47)
- The development of obesity in animals: the role of dietary factors. (1984) (46)
- Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα (2014) (45)
- An immortalised astrocyte cell line maintains the in vivo phenotype of a primary porcine in vitro blood–brain barrier model (2012) (44)
- Interleukin‐18 induces expression and release of cytokines from murine glial cells: interactions with interleukin‐1β (2003) (44)
- Central activation of thermogenesis by prostaglandins: dependence on CRF. (1990) (44)
- The expanding interleukin-1 family and its receptors (2003) (44)
- IL-1Rrp2 expression and IL-1F9 (IL-1H1) actions in brain cells (2003) (43)
- Regional blood flow and skeletal muscle energy status in endotoxemic rats. (1987) (43)
- Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons (2019) (43)
- Dietary N-3 fatty acids inhibit ischaemic and excitotoxic brain damage in the rat (1993) (43)
- Biodistribution, pharmacokinetics and metabolism of interleukin‐1 receptor antagonist (IL‐1RA) using [18F]‐IL1RA and PET imaging in rats (2011) (42)
- Effects of the beta 2-adrenoceptor agonist, clenbuterol, on muscle atrophy due to food deprivation in the rat. (1990) (42)
- Importance of brain IL-1 type II receptors in fever and thermogenesis in the rat. (1993) (41)
- Central control of brown adipose tissue (1989) (40)
- Integrin-binding RGD peptides induce rapid intracellular calcium increases and MAPK signaling in cortical neurons (2007) (40)
- Factors influencing the acute effect of food on oxygen consumption in the rat. (1982) (40)
- Differential effects of interleukin-1 alpha and beta on interleukin-6 and chemokine synthesis in neurones (2008) (40)
- Muscle wasting associated with endotoxemia in the rat: Modification by theβ2-adrenoceptor agonist clenbuterol (1989) (40)
- Fever and thermogenesis in response to bacterial endotoxin involve macrophage-dependent mechanisms in rats. (1993) (39)
- Central and haematopoietic interleukin-1 both contribute to ischaemic brain injury in mice (2013) (39)
- Activation of thermogenesis of brown fat in rats by Baclofen (1986) (38)
- Central administration of rat IL-6 induces HPA activation and fever but not sickness behavior in rats. (1999) (38)
- Sympathetic and thyroid influences on metabolic rate in fed, fasted, and refed rats. (1982) (38)
- The interleukin-1-related cytokine IL-1F8 is expressed in glial cells, but fails to induce IL-1beta signalling responses. (2005) (38)
- Aging aggravates ischemic stroke‐induced brain damage in mice with chronic peripheral infection (2013) (37)
- Interleukin-1 Mediates Neuroinflammatory Changes Associated With Diet-Induced Atherosclerosis (2012) (37)
- Effects of adrenalectomy on energy balance, diet-induced thermogenesis and brown adipose tissue in adult cafeteria-fed rats. (1984) (37)
- Impaired effects of interleukin-1 beta on fever and thermogenesis in genetically obese rats. (1989) (37)
- Interleukin-1 drives cerebrovascular inflammation via MAP kinase-independent pathways. (2010) (37)
- Central actions of CRF on thermogenesis are mediated by pro-opiomelanocortin products (1991) (37)
- Increased brown adipose tissue activity in children with malignant disease. (1989) (36)
- Identification of a truncated IL-18Rβ mRNA: a putative regulator of IL-18 expressed in rat brain (2003) (36)
- In vivo determination of body composition by tritium dilution in the rat (1979) (36)
- Effects of ciglitazone on energy balance, thermogenesis and brown fat activity in the rat (1987) (36)
- Sympathetic and adrenocorticoid influences on diet-induced thermogenesis and brown fat activity in the rat. (1984) (36)
- Influence of noradrenaline on blood flow to brown adipose tissue in rats exhibiting diet-induced thermogenesis (1981) (35)
- The Dynamics and Mechanisms of Interleukin-1α and β Nuclear Import (2008) (35)
- Influence of environmental temperature on energy balance, diet-induced thermogenesis and brown fat activity in ‘cafeteria’-fed rats (1986) (34)
- The endocrine significance of cytokines. (1991) (34)
- Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity (2014) (33)
- Effects of early overnutrition and undernutrition in rats on the metabolic responses to overnutrition in later life. (1982) (32)
- Metabolic and febrile responses to typhoid vaccine in humans: effect of beta-adrenergic blockade. (1992) (31)
- Acute effects of fat and carbohydrate on metabolic rate in normal, cold-acclimated and lean and obese (fa/fa) Zucker rats. (1983) (31)
- Central actions of interleukin-8 in the rat are independent of prostaglandins. (1990) (31)
- Role of insulin in thermogenic responses to refeeding in 3-day-fasted rats. (1983) (31)
- Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming. (2018) (30)
- Effects of subdiaphragmatic vagotomy on energy balance and thermogenesis in the rat. (1985) (30)
- Involvement of sympathetic nervous system and brown fat in endotoxin-induced fever in rats. (1988) (30)
- Influence of alcohol and sucrose consumption on energy balance and brown fat activity in the rat. (1984) (30)
- Mechanisms of interleukin-6 synthesis and release induced by interleukin-1 and cell depolarisation in neurones (2008) (29)
- Surgical removal of brown fat results in rapid and complete compensation by other depots. (1989) (28)
- Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo (2000) (28)
- Long-term functional recovery and compensation after cerebral ischemia in rats (2014) (28)
- Characterization of a conditional interleukin‐1 receptor 1 mouse mutant using the Cre/LoxP system (2016) (28)
- Na+, K+-ATPase activity and noradrenaline turnover in brown adipose tissue of rats exhibiting diet-induced thermogenesis. (1981) (28)
- Ca Stores and Ca Entry Differentially Contribute to the Release of IL-1 and IL-1 from Murine Macrophages (2003) (27)
- Neurohormonal control of cytokines during injury (1994) (27)
- Catecholamine and thyroid hormone influence on brown fat Na+, K+-ATPase activity and thermogenesis in the rat. (1982) (27)
- Anabolic effects of clenbuterol after long-term treatment and withdrawal in t the rat. (1994) (27)
- Changes in body composition, brown adipose tissue activity and thermogenic capacity in BN/BiRij rats undergoing senescence (1988) (26)
- Acute central effects of interleukin-6 on body temperature, thermogenesis and food intake in the rat (1989) (26)
- Inhibition of the thermogenic and pyrogenic responses to interleukin-1 beta in the rat by dietary N-3 fatty acid supplementation. (1993) (26)
- SYMPATHETIC MECHANISMS IN DIET‐INDUCED THERMOGENESIS: MODIFICATION BY CICLAZINDOL AND ANORECTIC DRUGS (1981) (26)
- Neurotoxic mechanisms of transactivating protein Tat of Maedi-Visna virus (1995) (26)
- Potential surrogate markers of cerebral microvascular angiopathy in asymptomatic subjects at risk of stroke (2009) (26)
- Clenbuterol, a beta 2-adrenergic agonist, reverses muscle wasting due to scald injury in the rat. (1993) (26)
- Neural regulation of thermogenesis (1982) (25)
- Interleukin-1 in the Brain (1992) (25)
- 16 – EFFECTS OF β-ADRENERGIC AGONISTS ON METABOLISM AND BODY COMPOSITION (1986) (25)
- Cytokines and thermogenesis. (1993) (24)
- Changes in tissue blood flow and beta-receptor density of skeletal muscle in rats treated with the beta2-adrenoceptor agonist clenbuterol. (1987) (24)
- Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis (2016) (24)
- Impaired febrile responses of aging mice are mediated by endogenous lipocortin-1 (annexin-1). (1993) (23)
- Combined effects of cafeteria and tube-feeding on energy balance in the rat. (1979) (23)
- Does Inflammation Predispose to Recurrent Vascular Events after Recent Transient Ischaemic Attack and Minor Stroke? the North West of England Transient Ischaemic Attack and Minor Stroke (NORTHSTAR) Study (2011) (23)
- The role of TNF-alpha in fever: opposing actions of human and murine TNF-alpha and interactions with IL-beta in the rat. (1996) (22)
- Mechanisms of cachexia induced by T-cell leukemia in the rat. (1996) (22)
- Cytokines and neurodegeneration (1997) (22)
- Obesity and Leanness: Basic Aspects (1982) (22)
- Interleukin‐1 as a pharmacological target in acute brain injury (2015) (22)
- Metabolic responses to fasting and refeeding in lean and genetically obese rats. (1983) (21)
- Involvement of interleukin-1 in glial responses to lipopolysaccharide: endogenous versus exogenous interleukin-1 actions (2000) (21)
- IL-1beta induced changes in hypothalamic IL-1R1 and IL-1R2 mRNA expression in the rat. (2000) (20)
- Immune responses in the nervous system (1997) (20)
- Selective increases in cytokine expression in the rat brain in response to striatal injection of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and interleukin-1. (2001) (20)
- Mechanisms of early and late hypermetabolism and fever after localized tissue injury in rats. (1991) (20)
- Dexamethasone inhibits the pyrogenic activity of prostaglandin F2α, but not prostaglandin E2 (1993) (20)
- Opposing effects of activation of central GABAA and GABA B receptors on brown fat thermogenesis in the rat (1988) (20)
- Site-specific actions of interleukin-1 on excitotoxic cell death in the rat striatum (2002) (20)
- Immune and Inflammatory Responses in the Nervous System (2002) (19)
- Influence of clenbuterol on energy balance, thermogenesis and body composition in lean and genetically obese Zucker rats. (1987) (19)
- Thermogenesis, brown adipose tissue and dexfenfluramine in animal studies. (1992) (19)
- The role of brown fat in diet-induced thermogenesis. (1986) (19)
- Energy balance, thermogenesis and brown adipose tissue activity in tube-fed rats. (1984) (19)
- Who Wants to be a Scientist?: Choosing Science as a Career (2002) (18)
- Effects of central injection of glucose on thermogenesis in normal, VMH-lesioned and genetically obese rats (1991) (18)
- Increased body-weight gain and body protein in castrated and adrenalectomized rats treated with clenbuterol (1988) (18)
- Comparison of the effects of several endotoxin preparations on body temperature and metabolic rate in the rat. (1989) (18)
- Effect of environmental temperature on energy balance and thermogenesis in rats fed normal or low protein diets. (1987) (18)
- Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages. (2000) (18)
- Correlation of systemic inflammatory response with infarct volume in acute ischemic stroke patients. (2005) (18)
- Identification of two mitochondrial GDP-binding sites in rat brown adipose tissue (1983) (18)
- Changes in adrenoreceptor density in brown adipose tissue from hyperthyroid rats. (1985) (17)
- Brain control of responses to trauma (1994) (17)
- Thermogenic capacity and brown adipose tissue activity in the common marmoset. (1985) (17)
- A comparison of the thermogenic effects of CRF, sauvagine and urotensin I in the rat. (1989) (17)
- Interleukin-1β and interleukin-1 receptor antagonist do not affect glutamate release or calcium entry in rat striatal synaptosomes (1998) (17)
- Dissociation between the effects of interleukin-1 on excitotoxic brain damage and body temperature in the rat (1999) (17)
- Survival in the cold — hibernation and other adaptations edited by X. J. Musacchia and L. Jansky, Elsevier/North Holland, 1981. Dfl. 121.00 (xiii + 225 pages) ISBN 0 444 00635 4 (1982) (16)
- Differential actions of IL-1 alpha and IL-1 beta in glial cells share common IL-1 signalling pathways (2005) (16)
- The Influence of Litter Size on Brain Damage Caused by Hypoxic-Ischemic Injury in the Neonatal Rat (2002) (16)
- Thermogenesis induced by cafeteria feeding in young growing rats. (1980) (16)
- Influence of thyroid hormone on diet-induced thermogenesis in the rat. (1983) (16)
- Oxidised adenosine 5′-triphosphate, a P2X7 antagonist, is toxic to rat cerebellar granule neurones in vitro (2001) (15)
- Involvement of insulin in the acute thermogenic responses to food and nonmetabolizable substances. (1985) (15)
- Role of IL-1a and IL-1b in Ischemic Brain Damage (2001) (15)
- Energy balance in reversible obesity (1979) (15)
- Factors influencing brown fat and the capacity for diet-induced thermogenesis. (1985) (15)
- Neuronal injury induces the release of pro-interleukin-1β from activated microglia in vitro (2008) (15)
- The Role of Cytokines in Neurodegeneration (1996) (15)
- Regional and Cellular Localization of Presenilin-2 RNA in Rat and Human Brain (1997) (14)
- Surgical manipulation compromises leukocyte mobilization responses and inflammation after experimental cerebral ischemia in mice (2014) (14)
- Intra-strain differences in the response to overfeeding in the rat. (1980) (14)
- Energy balance and brown fat activity in adrenalectomized male, female, and castrated male rats. (1986) (14)
- Whole body metabolic responses to brain trauma in the rat. (1997) (14)
- Adrenalectomy reverses the impaired pyrogenic responses to interleukin-beta in obese Zucker rats. (1990) (14)
- Acute and chronic effects of ACTH on thermogenesis and brown adipose tissue in the rat. (1985) (13)
- Contribution of Interleukin-1 Receptor Accessory Protein b to Interleukin-1 Actions in Neuronal Cells (2011) (13)
- Chronic effects of interleukin-1 beta on fever, oxygen consumption and food intake in the rat. (1993) (13)
- Brown adipose tissue: does it play a role in the development of obesity? (1988) (13)
- Protein synthesis in liver, skeletal muscle, and brown adipose tissue of rats fed a protein-deficient diet (1983) (13)
- Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist (2016) (13)
- Thermogenic effects of thyrotrophin-releasing hormone and its analogues in the rat (1988) (13)
- Dopaminergic mechanisms in diet-induced thermogenesis and brown adipose tissue metabolism. (1982) (12)
- An Endovascular Perforation Model of Subarachnoid Haemorrhage in Rat Produces Heterogeneous Infarcts that Increase with Blood Load (2012) (12)
- Thermogenic responses to adrenoceptor agonists and brown fat adrenoceptors in overfed rats. (1986) (12)
- Energy balance and brown adipose tissue thermogenesis during chronic endotoxemia in rats. (1989) (12)
- Thermogenesis and sympathetic activity in BAT of overfed rats after adrenalectomy. (1986) (12)
- Effect of age and gene dosage on brown adipose tissue of Zucker obese fa/fa rats. (1984) (11)
- Sympathetic control of brown adipose tissue in the regulation of body weight. (1981) (11)
- Cortical Death Caused by Striatal Administration of AMPA and Interleukin-1 is Mediated by Activation of Cortical NMDA Receptors (2000) (11)
- Translational pharmacokinetics: challenges of an emerging approach to drug development in stroke (2011) (11)
- Role of Brown Adipose Tissue Thermogenesis in Overfeeding: A Review 1 (1983) (11)
- Bacterial infection (Legionella pneumophila) stimulates fever, metabolic rate and brown adipose tissue activity in the guinea pig. (1989) (11)
- Effects of an analogue of thyrotrophin-releasing hormone, RX77368, on infarct size and cerebral blood flow in focal cerebral ischaemia in the rat. (1989) (11)
- Effect of noradrenaline on oxygen consumption and tissue blood flow in young pigs. (1984) (10)
- REVIEW ■ : Interleukin-1 and Neurodegeneration (1998) (10)
- Influence of subdiaphragmatic vagotomy and brown fat sympathectomy on thermogenesis in rats. (1985) (10)
- Acute effects of food, 2-deoxy-d-glucose and noradrenaline on metabolic rate and brown adipose tissue in normal and atropinised lean and obese (fa/fa) Zucker rats (1981) (10)
- Evidence for diet-induced thermogenesis in hyperphagic cafeteria-fed rats (1982) (10)
- Effects of malaria on O2 consumption and brown adipose tissue activity in mice. (1989) (10)
- Acute influences on the two GDP-binding sites in brown-adipose-tissue mitochondria (1984) (10)
- Spontaneous and experimental variations in body weight, food intake and metabolic rate in captive dormice (Glis glis). (1986) (10)
- Thermogenic actions of tryptophan in the rat are mediated independently of 5-HT (1992) (10)
- Mechanisms of weight gain and loss in reversible obesity in the rat [proceedings]. (1978) (10)
- Central activation of thermogenesis and fever by interleukin-1 beta and interleukin-1 alpha involves different mechanisms. (1989) (10)
- Parasympathethic effects on diet-induced thermogenesis. (1983) (10)
- Dose-dependent effects of an anabolic steroid, nandrolone phenylpropionate (Durabolin), on body composition and muscle protein metabolism in female rats. (1991) (10)
- Tissue blood flow in control and cold-adapted hyperthyroid rats. (1984) (10)
- Changes in metabolic rate and brown adipose tissue composition during nutritional rehabilitation of postnatally undernourished rats. (1982) (9)
- Beta-adrenoreceptors in rat brown adipose tissue: proportions of beta 1- and beta 2-subtypes. (1985) (9)
- Diurnal variations in circulating hormone levels and brown adipose tissue activity in "cafeteria"-fed rats. (1983) (9)
- Psychoneuroimmunology of stroke. (2006) (9)
- Perspectives Series: Cytokines and The Brain The Role of Interleukin 1 in Acute Neurodegeneration and Stroke: Pathophysiological and Therapeutic Implications (1997) (9)
- Brown adipose tissue and the response to overfeeding. (1986) (8)
- Thermogenic properties of ciclazindol and mazindol in rodents. (1984) (8)
- Central control of cardiovascular responses to injury (1994) (8)
- Psychoneuroimmunology of stroke. (2009) (8)
- Influence of adrenalectomy on age-related changes in energy balance, thermogenesis and brown fat activity in the rat. (1988) (8)
- Further functions of IL-6. (1991) (8)
- Radiolabeling with fluorine-18 of a protein, interleukin-1 receptor antagonist. (2010) (7)
- Obesity and cachexia : physiological mechanisms and new approaches to pharmacological control (1991) (7)
- Release of IL-1alpha or IL-1beta depends on mechanism of cell death (2014) (7)
- β-Adrenoreceptors in rat brown adipose tissue: proportions of β1- and β2-subtypes (1985) (7)
- Relationship between Interleukin‐1 and Interleukin‐1 Receptor Antagonist during the Development of Fever in the Rat a (1998) (7)
- Lipolytic and lipogenic activities of adipose tissue during spontaneous fat depletion and repletion [proceedings]. (1976) (7)
- Dexamethasone inhibits the pyrogenic activity of prostaglandin F2 alpha, but not prostaglandin E2. (1993) (7)
- Metabolic responses to interleukin-1 (1992) (7)
- Dietary n-3 Fatty Acids Inhibit Fever Induced by Inflammation in the Rat (1994) (6)
- The effect of interleukin-1 on local brain temperature during focal cerebral ischemia in the rat: a 1 H magnetic resonance spectroscopic imaging study (2006) (6)
- Interleukin‐6 and acute ischaemic stroke (2005) (6)
- Involvement of prostaglandins in cachexia induced by T-cell leukemia in the rat. (1997) (6)
- Localization of lipocortin-1 in normal rat brain. (1990) (6)
- Up-regulation of IL-18BP, but not IL-18 mRNA in rat liver by LPS. (2003) (6)
- Thermogenesis and BAT activity in hypophysectomized rats with and without corticotropin replacement. (1985) (6)
- Anabolic beta-2-agonist clenbuterol fails to modify muscle atrophy due to femur fracture. (1990) (5)
- Influence of sodium intake on thermogenesis and brown adipose tissue in the rat. (1984) (5)
- Metabolic responses to food atropine and 2 deoxy d glucose in zucker rats (1982) (5)
- Psychoneuroimmunology (Fourth Edition) (2007) (5)
- Chronic inhibition of GABA transaminase results in activation of thermogenesis and brown fat in the rat. (1988) (5)
- Modeling Risk Factors and Confounding Effects in Stroke (2010) (5)
- Effects of tube-feeding iso-energetic amounts of various dietary lipids on energy balance in the rat. (1979) (5)
- Effects of histamine antagonists on noradrenaline-stimulated blood flow and oxygen consumption of brown adipose tissue in the rat (1984) (5)
- Lipocortin-1 inhibits CRH stimulation of plasma ACTH and IL-1 beta-stimulated hypothalamic CRH release in rats. (1996) (5)
- Effect of hypophysectomy on energy balance and brown fat activity in obese Zucker rats. (1988) (5)
- Interleukin-1 and IL-1 receptor antagonist in stroke: mechanisms and potential therapeutics (2001) (5)
- Muscling in on salbutamol (1992) (4)
- Involvement of cytokines in cachexia induced by T-cell leukaemia in the rat. (1997) (4)
- Central control of pain (1994) (4)
- Thermogenic Effects of Cytokines: Methods and Mechanisms (1993) (4)
- Central nervous system control of sickness behavior (1994) (4)
- Responses to injury (1994) (4)
- Effects of continuous and discontinuous periods of cafeteria feeding on body weight, resting oxygen consumption and noradrenaline sensitivity in the rat [proceedings]. (1979) (4)
- Correction: Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome (2004) (4)
- Body weight and brown fat activity in hyperphagic cafeteria-fed female rats and their offspring. (1986) (3)
- Endogenous mediators of cerebral ischaemia-induced hypermetabolism in the rat. (1989) (3)
- Dopamine beta-hydroxylase inhibition reveals a selective influence of endotoxin on catecholamine content of rat tissues. (1990) (3)
- Psychological and behavioural aspects of pain (1994) (3)
- Neuroendocrine mechanisms in the thermogenic responses to diet, infection, and trauma. (1990) (3)
- IL-1 receptor antagonist inhibits the endotoxin-induced rise in plasma IL-6 in the rat. (1994) (3)
- Cytokines in Alzheimer’s and Other Neurodegenerative Diseases (1996) (3)
- Brown adipose tissue and diet-induced thermogenesis (reply) (1981) (3)
- Is diet-induced thermogenesis an experimental artefact? (1985) (3)
- Brown adipose tissue activity and oxygen consumption after scald injury in the rat. (1991) (3)
- Pyrogenic and thermogenic effects of recombinant interleukin-1beta in the rabbit and the rat (1987) (3)
- Role of IL-1(alpha) and IL-1(beta) in ischemic brain damage (vol 21, pg 5528, 2001) (2001) (3)
- Thermogenic effects of dihydrocodeine in the rat. (1988) (2)
- EFFECTS OF COLD AND HYPOXIA ON DIET-INDUCED THERMOGENESIS (1981) (2)
- Show them how it's really done (2000) (2)
- Hormonal and metabolic responses to fasting and refeeding. (1985) (2)
- Physical changes associated with the onset of precocious puberty in rats after treatment with PMSG. (1983) (2)
- Neuroendocrine responses to physical trauma (1994) (2)
- Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection (2012) (2)
- Brain regions involved in modulation of immune responses (1994) (2)
- Platelet interleukin-1 (cid:1) drives cerebrovascular inflammation (2010) (2)
- THE INVOLVEMENT OF CORTICOTROPHIN-RELEASING FACTOR (CRF) IN THE MODULATIONOF THE BAROREFLEX BY HINDLIMB ISCHAEMIA IN THE ANAESTHETIZED CAT (1991) (2)
- Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro (2017) (2)
- Thermogenesis in Obesity and Cachexia (1990) (2)
- In fl ammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage (2012) (2)
- Sympathetically mediated hypermetabolic response to cerebral ischemia in the rat. (1990) (2)
- Who wants to be a scientist (2002) (1)
- Robotics, automation and artificial intelligence (RAAI) (2017) (1)
- CHAPTER 19 – Cytokines and Non-immune Brain Injury (2007) (1)
- Interactions of cannabinoids and anti-inflammatory cytokines in astrocyte mice cultures (1999) (1)
- My Photos, My Story: An Account of College Learners' Voices (2008) (1)
- SUBCUTANEOUS INTERLEUKIN-1 RECEPTOR ANTAGONIST IN ISCHEMIC STROKE (SCIL-STROKE): A RANDOMIZED CONTROLLED PHASE 2 TRIAL (2018) (1)
- THERMOGENESIS IN PIGS (1980) (1)
- Influence of chronic administration of ciclazindol on energy balance and brown adipose tissue in adult 'cafeteria'-fed rats. (1983) (1)
- Interleukin-1 and platelets as key drivers of cerebrovascular inflammation (2011) (1)
- Acute neurodegeneration: cerebral ischaemia and stroke (2008) (1)
- One more thing... (2004) (1)
- Reduced thermogenic responses to interleukin-1beta in genetically obese Zucker rats (1988) (1)
- Neuronal toll-like receptor 4 signaling induces brain endothelial activation and neutrophil transmigration in vitro (2012) (1)
- Thermogenic Effects of TRH and Its Analogues in the Rat (1989) (1)
- In fl ammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage (2013) (1)
- 100 NF-κB Activation by Mal/Tirap is Regulated by Caspase-1 (2007) (1)
- Central effects of interleukin-1beta and tumour necrosis factor-alpha on brown adipose tissue thermogenesis in genetically obese rats and mice (1989) (1)
- Pro-inflammatory cytokine interleukin-1β affects synaptic plasticity in mouse hippocampal slices (2002) (1)
- Selective macrophage depletion attenuates early thermogenic responses to endotoxin in rats (1991) (1)
- Leptin induces nitric oxide production from rat astrocyte primary cultures (1998) (1)
- Involvement of angiotensin in hypermetabolic responses to injury and interleukin-1β in the rat (1989) (1)
- Contents, Vol. 109, 1996 (1996) (0)
- Scientific ethics and conduct (2002) (0)
- Who Wants to be a Scientist?: Starting out in research (2002) (0)
- Who Wants to be a Scientist?: Social aspects of science (2002) (0)
- Who Wants to be a Scientist?: Getting down to research (2002) (0)
- EUSI-ESO News (2008) (0)
- Who owns science (2002) (0)
- Neuroinflammatory changes in cerebral ischaemia and other central nervous system (CNS) diseases are driven by both activated glia and peripheral immune cells (Ransohoff and Brown, 2012; Denes (2013) (0)
- The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial (2014) (0)
- Halt on Cambridge primate centre: Nancy Rothwell considers what it means for the future of UK research (2004) (0)
- No paradox in the control of energy intake (reply) (1978) (0)
- Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist (2015) (0)
- EFFECT OF DELAYED ADMINISTRATION OF INTERLEUKIN-1 RECEPTOR ANTAGONIST ON NEUROGENESIS AFTER EXPERIMENTAL STROKE IN YOUNG/ AGED RATS (2016) (0)
- Brain Temperature and Interleukin-1 in Focal Cerebral Ischaema (2007) (0)
- Contributors to Volume 17 (1993) (0)
- An Endovascular Perforation Model of Subarachnoid Haemorrhage in Rat Produces Heterogeneous Infarcts that Increase with Blood Load (2011) (0)
- Experimental approaches to the central nervous system control of responses to trauma (1994) (0)
- Biomarkers of Cerebral Microvascular Angiopathy in Healthy Subjects at Risk of Stroke (2007) (0)
- The role of TNF-a in fever: opposing actions of human and murine TNF-oa and interactions with IL-fl in the rat (2006) (0)
- Sites and mechanisms of IL-1 action in ischemic and excitotoxic brain damage (2002) (0)
- Anandamide suppresses nitric oxide production in response to LPS in primary astrocytes mouse cultures by a mechanism mediated by the central cannabinoid receptor (CB1) (1998) (0)
- 1484 Penetration of interleukin-1 receptor antagonist into the cerebrospinal fluid of patients with subarachnoid haemorrhage (2005) (0)
- Systemic inflammatory stimulus exacerbates brain damage after experimental stroke via a matrix metalloproteinase-9-dependent mechanism that targets the neurovascular unit (2007) (0)
- Effects of obesity on the brain-mediated inflammatory response and recovery from neuronal injury (2008) (0)
- Interleukin-1 in the Brain Interleukin-1 in the Brain (2010) (0)
- Decondensed DNA Release of Proteases Associated with Triggers Rapid Neurotoxicity through Neutrophil Cerebrovascular Transmigration (2012) (0)
- Effect of a Selective ( Clenbuterol ) on Energy Composition in Normal Deficient Rats (2005) (0)
- Animal experiments and the development of surgical therapies. (2005) (0)
- IL-1β is involved in temperature-associated changes in synaptic plasticity in mouse hippocampal slices (2002) (0)
- Research report Influence of corticotrophin releasing factor on neuronal cell death in vitro and in vivo (2000) (0)
- Whither Brown Fat ? 5 thermogenic responsiveness ( Thurlby and Trayhurn (2005) (0)
- Use of interference reflection microscopy to monitor exocytosis and endocytosis in the presynaptic terminal of bipolar cells from the goldfish retina (2002) (0)
- Effects of energy restriction and cafeteria refeeding on thermogenesis in the rat. (1980) (0)
- BJORNTORP FELLOWSHIP AW0006 The involvement of galanin-like peptide in energy balance: a role for inflammation? (2006) (0)
- MECHANISMS OF INTERLEUKIN-1 NEUROTOXICITY ARE MEDIATED BY MATRIX METALLOPROTEINASE-9 IN PRIMARY CULTURES (2011) (0)
- Q&A: Back to school: Prominent figures in physiology share memories of their school days (2013) (0)
- Boron-Based Inhibitors of the NLRP 3 Inflammasome Graphical Abstract Highlights (0)
- Psychological and neurobiological consequences of trauma (1994) (0)
- Murine Macrophages α and IL-1 β Contribute to the Release of IL-1 Entry Differentially 2 + Stores and Ca 2 + Ca (2003) (0)
- Interleukin-1β release requires both calcium release from intracellular calcium stores and potassium ion efflux in murine macrophages (2002) (0)
- The final word (1994) (0)
- Central control of metabolic and thermoregulatory responses to injury (1994) (0)
- Inflammation and risk of recurrent vascular events after TIA and minor stroke: the NORTHSTAR study (2009) (0)
- Interleukin-1 as a therapeutic target in acute brain injury (2006) (0)
- Weight maintenance and dietary-induced thermogenesis in the weanling pig [proceedings ]. (1979) (0)
- IL-1b signalling in glial cells in wildtype and IL-1RI de®cient mice (2002) (0)
- The effect of adrenalectomy on neuropeptide Y concentrations in individual hypothalamic nuclei of the obese (fa/fa) Zucker rat (1991) (0)
- Abstracts of Communications (1982) (0)
- Involvement of interleukin-1β (IL-1β) in cerebral ischaemia (1992) (0)
- Calcium regulation by calcium binding proteins in neurodegenerative disorders: C. W. Heizmann and K. Braun, 136 pages, 1995 Landes Company, Austin, USA £46.00 (1995) (0)
- Amount is not supply rate in energy intake control (reply) (1979) (0)
- Contents Vol. 32, 2011 (2011) (0)
- Peripheral administration of interleukin-1β exacerbates ischaemic brain damage after transient focal ischaemia in mice (2005) (0)
- Adrenolectomy reverses the impaired pyrogenic responses to interleukin-1 in obese Zucker rats (1990) (0)
- Central administration of lipocortin reduces severity of mild experimental alleric encephalomyelitis (1994) (0)
- Endogenous interleukin-1 plays a role in LTP induction (2003) (0)
- Inflammation and reperfusion injury within the penumbra. (2007) (0)
- Amount is not supply rate in energy intake control (reply) (1979) (0)
- Printed in Great Britain Brown fa t ac t iv i ty in fasted and re fed rats (0)
- Cell density regulates nuclear localisation of interleukin-1α and β in murine microglia (2007) (0)
- Nancy Rothwell, UK (2015) (0)
- Contents Vol. 19, 2011 (2011) (0)
- Animal Experiments and the Doctor (2002) (0)
- Why so few (1999) (0)
- Who Wants to be a Scientist?: Science and the public (2002) (0)
- Scientific Progress and Animal Welfare: Conflicting Goals or Complementary Opportunities? (2001) (0)
- Who Wants to be a Scientist?: Funding research (2002) (0)
- Who Wants to be a Scientist?: Introduction (2002) (0)
- The Animal Science Group: Supporting Excellence in the Science Base (2003) (0)
- Subject Index Vol. 109, 1996 (1996) (0)
- Choices in neuroscience careers (2008) (0)
- Publish or perish (2002) (0)
- THE FUTURE OF BIOLOGY IN THE UK (2005) (0)
- Who Wants to be a Scientist?: Communication and getting known (2002) (0)
- Who Wants to be a Scientist?: Power, pressure and politics (2002) (0)
- So who does want to be a scientist (2002) (0)
- Who Wants to be a Scientist?: Preface (2002) (0)
- Can you hear me through my photos? Engaging learners at-risk to understand their experience in college (2008) (0)
- Who Wants to be a Scientist?: Responsibilities (2002) (0)
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