Piu Chan
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Computer Science
Piu Chan's Degrees
- Masters Artificial Intelligence National University
- Bachelors Computer Science National University
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(Suggest an Edit or Addition)Piu Chan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- MDS clinical diagnostic criteria for Parkinson's disease (2015) (3560)
- MDS research criteria for prodromal Parkinson's disease (2015) (897)
- Frailty: An Emerging Public Health Priority. (2016) (455)
- Time to Redefine PD? Introductory Statement of the MDS Task Force on the Definition of Parkinson's Disease (2014) (384)
- Association between genetic variation of CACNA1H and childhood absence epilepsy (2003) (372)
- Regional homogeneity changes in patients with Parkinson's disease (2009) (368)
- Changes of functional connectivity of the motor network in the resting state in Parkinson's disease (2009) (346)
- The Asia-Pacific Clinical Practice Guidelines for the Management of Frailty. (2017) (344)
- Motor automaticity in Parkinson's disease (2015) (225)
- Effective connectivity of brain networks during self-initiated movement in Parkinson's disease (2011) (193)
- Single-Cell Transcriptomic Atlas of Primate Ovarian Aging (2020) (190)
- Extensive nuclear localization of α-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody (2007) (182)
- Functional connectivity of cortical motor areas in the resting state in Parkinson's disease (2011) (181)
- Neural correlates of bimanual anti-phase and in-phase movements in Parkinson's disease. (2010) (154)
- Validation of the MDS clinical diagnostic criteria for Parkinson's disease (2018) (153)
- Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging (2020) (147)
- The past, present, and future of telemedicine for Parkinson's disease (2014) (142)
- Basal ganglia circuits changes in Parkinson's disease patients (2012) (118)
- Semi-quantitative analysis of α-synuclein in subcellular pools of rat brain neurons: An immunogold electron microscopic study using a C-terminal specific monoclonal antibody (2008) (116)
- Epidemiology of Parkinson's disease (2016) (113)
- Effective connectivity of neural networks in automatic movements in Parkinson's disease (2010) (111)
- Voxel-based analysis of diffusion tensor indices in the brain in patients with Parkinson's disease. (2011) (108)
- Loss of MAP Function Leads to Hippocampal Synapse Loss and Deficits in the Morris Water Maze with Aging (2014) (107)
- Health related quality of life in early Parkinson's disease: impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort. (2009) (107)
- Inhibition of tyrosine hydroxylase expression in α-synuclein-transfected dopaminergic neuronal cells (2004) (105)
- Gradual Disturbances of the Amplitude of Low-Frequency Fluctuations (ALFF) and Fractional ALFF in Alzheimer Spectrum (2018) (105)
- Modifications of the interactions in the motor networks when a movement becomes automatic (2008) (98)
- Movement disorder society criteria for clinically established early Parkinson's disease (2018) (96)
- Aging influence on functional connectivity of the motor network in the resting state (2007) (95)
- Cerebellum and integration of neural networks in dual-task processing (2013) (92)
- Prevalence of Frailty and Associated Factors in the Community‐Dwelling Population of China (2018) (89)
- Attention to Automatic Movements in Parkinson's Disease: Modified Automatic Mode in the Striatum. (2015) (89)
- Motor and nonmotor heterogeneity of LRRK2‐related and idiopathic Parkinson's disease (2016) (88)
- Chronobiological Analysis of Circadian Patterns in Transcription of Seven Key Clock Genes in Six Peripheral Tissues in Mice (2007) (85)
- A Single-Cell Transcriptomic Atlas of Human Skin Aging. (2020) (81)
- Clinical profiles of Parkinson's disease associated with common leucine-rich repeat kinase 2 and glucocerebrosidase genetic variants in Chinese individuals (2014) (79)
- Integrated and patient-centred management of Parkinson's disease: a network model for reshaping chronic neurological care (2020) (78)
- Prevalence and Incidence of Frailty in Community‐Dwelling Older People: Beijing Longitudinal Study of Aging II (2016) (77)
- Differentiation of human induced pluripotent stem cells to mature functional Purkinje neurons (2015) (74)
- The new definition and diagnostic criteria of Parkinson's disease (2016) (74)
- Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis (2019) (73)
- Normal aging decreases regional homogeneity of the motor areas in the resting state (2007) (73)
- Parkinson disease with REM sleep behavior disorder (2015) (72)
- Association of ARNTL and PER1 genes with Parkinson's disease: a case-control study of Han Chinese (2015) (72)
- Chemical screen identifies a geroprotective role of quercetin in premature aging (2018) (72)
- α-Synuclein and dopamine metabolism (2007) (70)
- The role of genetics in Parkinson's disease: a large cohort study in Chinese mainland population. (2020) (69)
- Hypoxic preconditioning up-regulates glucose transport activity and glucose transporter (GLUT1 and GLUT3) gene expression after acute anoxic exposure in the cultured rat hippocampal neurons and astrocytes (2008) (68)
- The prevalence and incidence of frailty in Pre-diabetic and diabetic community-dwelling older population: results from Beijing longitudinal study of aging II (BLSA-II) (2017) (66)
- Parkinson disease with constipation: clinical features and relevant factors (2018) (66)
- Coding mutations in NUS1 contribute to Parkinson’s disease (2018) (66)
- A single-cell transcriptomic landscape of primate arterial aging (2020) (65)
- Neural correlates underlying micrographia in Parkinson's disease. (2016) (65)
- Impulse control disorders in Parkinson's disease in a Chinese population (2009) (64)
- Promoter methylation analysis of seven clock genes in Parkinson's disease (2012) (64)
- α‐Synuclein promotes clathrin‐mediated NMDA receptor endocytosis and attenuates NMDA‐induced dopaminergic cell death (2011) (63)
- α-Synuclein aggregation and neurodegenerative diseases (2003) (60)
- Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants. (2012) (59)
- Oxidative stress induces nuclear translocation of C-terminus of alpha-synuclein in dopaminergic cells. (2006) (59)
- Frequency‐dependent neural activity in Parkinson's disease (2014) (59)
- Single-cell transcriptomic atlas of primate cardiopulmonary aging (2020) (58)
- Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. (2019) (57)
- Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis (2019) (56)
- Silencing α-Synuclein Gene Expression Enhances Tyrosine Hydroxylase Activity in MN9D Cells (2008) (55)
- Motoric Cognitive Risk Syndrome: Predictor of Dementia and Age-Related Negative Outcomes (2017) (54)
- Dopamine Transporter Binding Is Unaffected by L-DOPA Administration in Normal and MPTP-Treated Monkeys (2010) (53)
- Correlation between Progressive Changes in Piriform Cortex and Olfactory Performance in Early Parkinson’s Disease (2011) (53)
- Increased oligomerization and phosphorylation of α-synuclein are associated with decreased activity of glucocerebrosidase and protein phosphatase 2A in aging monkey brains (2015) (53)
- FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. (2019) (53)
- α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator. (2011) (52)
- Waist circumference is a better predictor of risk for frailty than BMI in the community-dwelling elderly in Beijing (2018) (51)
- Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice (2010) (50)
- ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells (2018) (48)
- Restless legs syndrome in Parkinson disease: Clinical characteristics, abnormal iron metabolism and altered neurotransmitters (2017) (48)
- Prevalence of frailty and contributory factors in three Chinese populations with different socioeconomic and healthcare characteristics (2015) (48)
- Ganoderma lucidum Protects Dopaminergic Neuron Degeneration through Inhibition of Microglial Activation (2011) (46)
- Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis (2018) (46)
- Concordance for Parkinson's disease in twins: A 20‐year update (2019) (45)
- Abolishing the 1‐year rule: How much evidence will be enough? (2016) (45)
- A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia (2021) (45)
- Decreased expression of Bmal2 in patients with Parkinson's disease (2011) (45)
- Understanding the Physiological Links Between Physical Frailty and Cognitive Decline (2020) (44)
- Autologous iPSC-derived dopamine neuron transplantation in a nonhuman primate Parkinson’s disease model (2015) (44)
- Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome (2018) (44)
- Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration (2020) (43)
- Pyrosequencing analysis of SNCA methylation levels in leukocytes from Parkinson's disease patients (2014) (43)
- Gender differences on motor and non-motor symptoms of de novo patients with early Parkinson’s disease (2014) (42)
- Rotigotine treatment partially protects from MPTP toxicity in a progressive macaque model of Parkinson's disease (2007) (41)
- Cognitive Frailty in China: Results from China Comprehensive Geriatric Assessment Study (2017) (41)
- The prodromal phase of leucine‐rich repeat kinase 2–associated Parkinson disease: Clinical and imaging Studies (2017) (41)
- Altered resting-state brain activity in Parkinson’s disease patients with freezing of gait (2017) (40)
- The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease (2016) (40)
- The effect of LRRK2 mutations on the cholinergic system in manifest and premanifest stages of Parkinson's disease: a cross-sectional PET study (2018) (39)
- A silicon based implantable microelectrode array for electrophysiological and dopamine recording from cortex to striatum in the non-human primate brain. (2016) (39)
- Parkinson's Disease—Related Spatial Covariance Pattern Identified with Resting-State Functional MRI (2015) (38)
- Three-Year Gait and Axial Outcomes of Bilateral STN and GPi Parkinson’s Disease Deep Brain Stimulation (2020) (38)
- Frequency-dependent changes in fractional amplitude of low-frequency oscillations in Alzheimer’s disease: a resting-state fMRI study (2019) (38)
- Motor Sequence Learning and Consolidation in Unilateral De Novo Patients with Parkinson’s Disease (2015) (37)
- Nuclear translocation of alpha-synuclein increases susceptibility of MES23.5 cells to oxidative stress (2013) (37)
- Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding (2017) (37)
- Alpha-synuclein and dopamine metabolism. (2005) (37)
- Real-time simultaneous recording of electrophysiological activities and dopamine overflow in the deep brain nuclei of a non-human primate with Parkinson’s disease using nano-based microelectrode arrays (2018) (37)
- Lateralization of brain activity pattern during unilateral movement in Parkinson's disease (2015) (37)
- Understanding and Meeting the Needs of the Older Population: A Global Challenge (2008) (37)
- Serotonergic dysfunctions and abnormal iron metabolism: Relevant to mental fatigue of Parkinson disease (2016) (36)
- Iron deposition in substantia nigra: abnormal iron metabolism, neuroinflammatory mechanism and clinical relevance (2017) (36)
- Increase expression of α-synuclein in aged human brain associated with neuromelanin accumulation (2011) (35)
- The cerebellum in dual-task performance in Parkinson’s disease (2017) (35)
- Phosphorylation of α-synuclein upregulates tyrosine hydroxylase activity in MN9D cells. (2011) (34)
- Interaction between Neuromelanin and Alpha-Synuclein in Parkinson’s Disease (2015) (34)
- NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy (2012) (33)
- Contemporary epidemiology of gout and hyperuricemia in community elderly in Beijing (2014) (32)
- No association between polymorphism of serotonin transporter gene and depression in Parkinson's disease in Chinese (2009) (31)
- Integrated Care for Older People Screening Tool for Measuring Intrinsic Capacity: Preliminary Findings From ICOPE Pilot in China (2020) (31)
- Alpha-synuclein aggregation and neurodegenerative diseases. (2003) (31)
- Heterogeneity among patients with Parkinson's disease: Cluster analysis and genetic association (2015) (31)
- High-frequency rTMS over the supplementary motor area improves freezing of gait in Parkinson's disease: a randomized controlled trial. (2019) (31)
- The Corticostriatal Adenosine A2A Receptor Controls Maintenance and Retrieval of Spatial Working Memory (2017) (31)
- Parkinson's Disease with Fatigue: Clinical Characteristics and Potential Mechanisms Relevant to α-Synuclein Oligomer (2016) (31)
- (-)-Epigallocatechin-3-Gallate protects SH-SY5Y cells against 6-OHDA-induced cell death through STAT3 activation. (2009) (30)
- Postural sway in patients with early Parkinson’s disease performing cognitive tasks while standing (2018) (29)
- Evaluation of the Risk Prediction Tools for Patients With Coronavirus Disease 2019 in Wuhan, China: A Single-Centered, Retrospective, Observational Study (2020) (29)
- Levodopa Effect on Basal Ganglia Motor Circuit in Parkinson's Disease (2017) (29)
- Marked variation in clinical presentation and age of onset in a family with a heterozygous parkin mutation (2003) (29)
- Quantitative Evaluation of Iron Content in Idiopathic Rapid Eye Movement Sleep Behavior Disorder (2019) (28)
- The impact of long-term exposure to ambient air pollution and second-hand smoke on the onset of Parkinson disease: a review and meta-analysis. (2019) (28)
- Stereopsis impairment is associated with decreased color perception and worse motor performance in Parkinson’s disease (2014) (28)
- Investigation on Abnormal Iron Metabolism and Related Inflammation in Parkinson Disease Patients with Probable RBD (2015) (28)
- Association of Catechol-O-Methyltransferase and monoamine oxidase B gene polymorphisms with motor complications in parkinson's disease in a Chinese population. (2014) (27)
- A single-cell transcriptomic atlas of primate pancreatic islet aging (2020) (27)
- Vascular, inflammatory and metabolic risk factors in relation to dementia in Parkinson’s disease patients with type 2 diabetes mellitus (2020) (26)
- Postural sway in idiopathic rapid eye movement sleep behavior disorder: A potential marker of prodromal Parkinson׳s disease (2014) (26)
- Clinical features and dysfunctions of iron metabolism in Parkinson disease patients with hyper echogenicity in substantia nigra: a cross-sectional study (2018) (26)
- Single-nucleus transcriptomic landscape of primate hippocampal aging (2021) (26)
- Low-dose quercetin positively regulates mouse healthspan (2019) (25)
- Phenotype of postural instability/gait difficulty in Parkinson disease: relevance to cognitive impairment and mechanism relating pathological proteins and neurotransmitters (2017) (25)
- Intrinsic Capacity as a Determinant of Physical Resilience in Older Adults (2021) (25)
- 3.120 ALPHA-SYNUCLEIN PROMOTES CLATHRIN-MEDIATED NMDA RECEPTOR ENDOCYTOSIS AND ATTENUATES NMDA-INDUCED DOPAMINERGIC CELL DEATH (2012) (24)
- Novel Frailty Screening Questionnaire (FSQ) Predicts 8-Year Mortality in Older Adults in China (2018) (24)
- Age- and brain region-dependent α-synuclein oligomerization is attributed to alterations in intrinsic enzymes regulating α-synuclein phosphorylation in aging monkey brains (2015) (24)
- Alpha-synuclein functions as a negative regulator for expression of tyrosine hydroxylase. (2011) (22)
- Brain-derived neurotrophic factor (BDNF) genetic polymorphism greatly increases risk of leucine-rich repeat kinase 2 (LRRK2) for Parkinson's disease. (2012) (22)
- Cholesteryl ester transfer protein polymorphism D442G associated with a potential decreased risk for Alzheimer's disease as a modifier for APOE ε4 in Chinese (2008) (22)
- Functional Connectivity of Vim Nucleus in Tremor‐ and Akinetic‐/Rigid‐Dominant Parkinson's Disease (2016) (21)
- Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Combined with Magnetic Beads for Detecting Serum Protein Biomarkers in Parkinson’s Disease (2011) (20)
- Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues. (2022) (20)
- Analysis of glucose metabolism in cynomolgus monkeys during aging (2012) (20)
- Cholesteryl ester transfer protein polymorphism D442G associated with a potential decreased risk for Alzheimer's disease as a modifier for APOE epsilon4 in Chinese. (2008) (20)
- Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons (2013) (20)
- Prevalence of Parkinson's Disease: A Community‐Based Study in China (2021) (20)
- Connectome-wide network analysis of white matter connectivity in Alzheimer's disease (2019) (20)
- Combined measurement of plasma cystatin C and low-density lipoprotein cholesterol: A valuable tool for evaluating progressive supranuclear palsy. (2018) (20)
- Non-motor symptoms in treated and untreated Chinese patients with early Parkinson's disease. (2014) (19)
- A common A340T variant in PINK1 gene associated with late-onset Parkinson's disease in Chinese (2006) (19)
- Risk factors for cognitive impairment in older people with diabetes: a community-based study (2019) (19)
- Postnatal ontogenesis of molecular clock in mouse striatum (2009) (19)
- Deciphering primate retinal aging at single-cell resolution (2020) (19)
- Different risk factors for cognitive impairment among community-dwelling elderly, with impaired fasting glucose or diabetes (2019) (19)
- 1‐Methyl‐4‐phenylpridinium (MPP+)‐induced functional run‐down of GABAA receptor‐mediated currents in acutely dissociated dopaminergic neurons (2002) (18)
- Repetitive transcranial magnetic stimulation improves Parkinson’s freezing of gait via normalizing brain connectivity (2020) (18)
- Linkage analysis and whole-exome sequencing exclude extra mutations responsible for the parkinsonian phenotype of spinocerebellar ataxia-2 (2015) (18)
- Management Recommendations on Sleep Disturbance of Patients with Parkinson's Disease (2018) (18)
- Non-motor symptoms in Chinese Parkinson’s disease patients with and without LRRK2 G2385R and R1628P variants (2015) (18)
- The underlying mechanism of prodromal PD: insights from the parasympathetic nervous system and the olfactory system (2017) (18)
- Intrinsic Capacity vs. Multimorbidity: A Function-Centered Construct Predicts Disability Better Than a Disease-Based Approach in a Community-Dwelling Older Population Cohort (2021) (18)
- A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia (2020) (17)
- Age-associated changes of cerebrospinal fluid amyloid-β and tau in cynomolgus monkeys (2014) (17)
- Preclinical and clinical neural network changes in SCA2 parkinsonism. (2013) (17)
- Repetitive Transcranial Magnetic Stimulation Does Not Improve the Sequence Effect in Freezing of Gait (2019) (17)
- CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells (2018) (17)
- Isolation and in vitro characterization of pancreatic progenitor cells from the islets of diabetic monkey models. (2006) (16)
- Age-related decline in motor behavior and striatal dopamine transporter in cynomolgus monkeys (2012) (16)
- Plasma immune markers in an idiopathic REM sleep behavior disorder cohort. (2020) (16)
- Prediction of Conversion From Amnestic Mild Cognitive Impairment to Alzheimer's Disease Based on the Brain Structural Connectome (2019) (16)
- Association between acyl-coenzyme A: cholesterol acyltransferase gene and risk for Alzheimer's disease in Chinese (2005) (16)
- Excessive Iron and α-Synuclein Oligomer in Brain are Relevant to Pure Apathy in Parkinson Disease (2016) (16)
- Protective role of interlekin-1 alpha gene polymorphism in Chinese Han population with sporadic Parkinson’s disease (2008) (16)
- Post-translational modifications of α-synuclein contribute to neurodegeneration in the colon of elderly individuals (2016) (16)
- Depressive symptoms impacting on health-related quality of life in early Parkinson's disease: Results from Chinese l-dopa exposed cohort (2009) (15)
- Association between common genetic risk variants and depression in Parkinson's disease: A dPD study in Chinese. (2016) (15)
- Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis (2021) (15)
- Strategies on fall prevention for older people living in the community: A report from a round-table meeting in IAGG 2013 (2015) (15)
- A Multicenter Study of Multimorbidity in Older Adult Inpatients in China (2020) (15)
- Structural and Functional Brain Alterations in Patients with Idiopathic Rapid Eye Movement Sleep Behavior Disorder. (2020) (15)
- Parkin dosage mutations in patients with early-onset sporadic and familial Parkinson's disease in Chinese: An independent pathogenic role (2010) (15)
- Prevention of Disability in the Frail Chinese Older Population (2018) (15)
- Reliability and validity of PDQ-39: a quality-of-life measure for patients with PD in China (2012) (15)
- Serum uric acid and impaired cognitive function in community-dwelling elderly in Beijing (2017) (15)
- Decreased subregional specificity of the putamen in Parkinson's Disease revealed by dynamic connectivity-derived parcellation (2018) (14)
- Exploring the Effects of Genetic Variants on Clinical Profiles of Parkinson’s Disease Assessed by the Unified Parkinson’s Disease Rating Scale and the Hoehn–Yahr Stage (2016) (14)
- Anti-parkinsonian effects of octacosanol in 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-treated mice☆ (2012) (14)
- C-terminal part of α-synuclein mediates its activity in promoting proliferation of dopaminergic cells (2011) (14)
- Smoking, genes encoding dopamine pathway and risk for Parkinson's disease (2010) (14)
- High-frequency repetitive transcranial magnetic stimulation over the primary motor cortex relieves musculoskeletal pain in patients with Parkinson's disease: A randomized controlled trial. (2020) (14)
- Large-scale chemical screen identifies Gallic acid as a geroprotector for human stem cells (2021) (14)
- Pyrosequencing analysis of methylation levels of clock genes in leukocytes from Parkinson’s disease patients (2018) (14)
- An objective measurement of locomotion behavior for hemiparkinsonian cynomolgus monkeys (2009) (14)
- Simple Physical Activity Index Predicts Prognosis in Older Adults: Beijing Longitudinal Study of Aging (2018) (13)
- Motoric Cognitive Risk Syndrome in a Chinese Older Adult Population: Prevalence and Associated Factors. (2019) (13)
- DJ-1 is dispensable for human stem cell homeostasis (2019) (13)
- Altered functional connectivity of the subthalamic nucleus during self-initiated movement in Parkinson's disease. (2017) (13)
- Impaired serial ordering in nondemented patients with mild Parkinson’s disease (2018) (12)
- Novel POLG mutation in a patient with early-onset parkinsonism, progressive external ophthalmoplegia and optic atrophy (2019) (12)
- FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction (2020) (12)
- MAPT IVS1+124 C>G modifies risk of LRRK2 G2385R for Parkinson's disease in Chinese individuals (2014) (11)
- Imaging of VMAT2 binding sites in the brain by (18)F-AV-133: the effect of a pseudo-carrier. (2012) (11)
- Olfactory Dysfunction in Parkinson’s Disease Patients with the LRRK2 G2385R Variant (2016) (11)
- Age-dependent alpha-synuclein accumulation is correlated with elevation of mitochondrial TRPC3 in the brains of monkeys and mice (2017) (11)
- Suprachiasmatic nucleus slices induce molecular oscillations in fibroblasts. (2008) (10)
- DYT1 mutations in early onset primary torsion dystonia and Parkinson disease patients in Chinese populations (2009) (10)
- Genetic association between low-density lipoprotein receptor-related protein gene polymorphisms and Alzheimer's disease in Chinese Han population (2008) (10)
- Reliability and validity of the self-reported frailty screening questionnaire in older adults (2020) (10)
- The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity (2021) (10)
- Progressive loss of striatal dopamine terminals in MPTP-induced acute parkinsonism in cynomolgus monkeys using vesicular monoamine transporter type 2 PET imaging ([18F]AV-133) (2014) (9)
- Brain activity in Parkinson’s disease patients with mild cognitive impairment (2016) (9)
- Oscillation development for neurotransmitter-related genes in the mouse striatum (2010) (9)
- Validation of the Beijing version of the REM sleep behavior disorder questionnaire (RBDQ-Beijing) in a mainland Chinese cohort. (2014) (9)
- New Onset On-Medication Freezing of Gait After STN-DBS in Parkinson's Disease (2019) (9)
- An integrated system for synchronous detection of neuron spikes and dopamine activities in the striatum of Parkinson monkey brain (2018) (9)
- Frailty in China: From Research to Practice (2021) (8)
- Michael J. Fox Foundation LRRK2 Consortium: geographical differences in returning genetic research data to study participants (2014) (8)
- Gait variability is sensitive to detect Parkinson’s disease patients at high fall risk (2020) (8)
- Genetic variants of the PITX3 gene are not associated with late-onset sporadic Parkinson's disease in a Chinese population (2011) (8)
- Associations between homocysteine, inflammatory cytokines and sarcopenia in Chinese older adults with type 2 diabetes (2021) (8)
- Role of α-synuclein in neurodegeneration: implications for the pathogenesis of Parkinson's disease. (2014) (8)
- Acute stepwise challenge test with levodopa in treated patients with parkinsonism. (2009) (8)
- Risk of mini-mental state examination (MMSE) decline in the elderly with type 2 diabetes: a Chinese community-based cohort study (2020) (7)
- The relationship between apolipoprotein (apo) E polymorphism and lipid changes: An 8-year cohort study in Beijing elderly persons. (2012) (7)
- Epigenetic analysis of mPer1 promoter in peripheral tissues (2009) (7)
- Allele-specific extension allows base-pair neutral homozygotes to be discriminated by high-resolution melting of small amplicons. (2010) (7)
- Visual dysfunction in patients with idiopathic rapid eye movement sleep behavior disorder (2019) (7)
- NIPA2 mutations are correlative with childhood absence epilepsy in the Han Chinese population (2014) (7)
- Poor self-perceived health is associated with frailty and prefrailty in urban living older adults: A cross-sectional analysis. (2020) (7)
- Clinical Manifestation of Parkinson's Disease in Association with Rapid Eye Movement Sleep Behavior Disorder Onset (2016) (7)
- Dopaminergic pathway and primary visual cortex are involved in the freezing of gait in Parkinson’s disease: a PET-CT study (2019) (7)
- An improved preparation of [18F]FPBM: a potential serotonin transporter (SERT) imaging agent. (2013) (7)
- PITX3 polymorphism is not associated with Parkinson's disease in a Chinese population (2011) (7)
- Clinicogenetics of Parkinson′s disease: a drawing but not completed picture (2014) (6)
- Severity of frailty as a significant predictor of mortality for hemodialysis patients: a prospective study in China (2021) (6)
- Low-dose chloroquine treatment extends the lifespan of aged rats (2022) (6)
- Prevalence of pre-diagnostic symptoms did not differ between LRRK2-related, GBA-related and idiopathic patients with Parkinson's disease. (2018) (6)
- Geriatric medicine in China: an old but emerging subspecialty. (2020) (6)
- Decreased Penetrance of Parkinson's Disease in Elderly Carriers of Glucocerebrosidase Gene L444P/R Mutations: A Community‐Based 10‐Year Longitudinal Study (2020) (6)
- Brain microglia activation and peripheral adaptive immunity in Parkinson’s disease: a multimodal PET study (2022) (6)
- Gene symbol: ATP7B. Disease: Wilson's Disease. (2005) (6)
- Screening of ferritin light polypeptide 460–461InsA mutation in Parkinson's disease patients in North America (2002) (6)
- Validation of the utility of the Brief Smell Identification Test in Chinese patients with Parkinson’s disease (2019) (6)
- Risk factors for possible REM sleep behavior disorders (2020) (5)
- Ischemia, immunosuppression, and SSEA‐1‐negative cells all contribute to tumors resulting from mouse embryonic stem cell‐derived neural progenitor transplantation (2014) (5)
- Impaired Fine Motor Function of the Asymptomatic Hand in Unilateral Parkinson’s Disease (2019) (5)
- CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells (2018) (5)
- P2.204 A randomized, double-blind, placebo-controlled, delayed start study to assess safty, tolerability and efflcacy of green tea polyphenols in Parkinson's disease (2009) (5)
- Education Moderates the Association of Probable REM Sleep Behavior Disorder With Cognitive and Motor Impairments in Community-Dwelling Older People (2020) (5)
- MPTP Induces Systemic Parkinsonism in Middle-Aged Cynomolgus Monkeys: Clinical Evolution and Outcomes (2017) (5)
- Repetitive transcranial magnetic stimulation improves Parkinson’s freezing of gait via normalizing brain connectivity (2020) (5)
- Deficiency in endocannabinoid synthase DAGLB contributes to early onset Parkinsonism and murine nigral dopaminergic neuron dysfunction (2022) (4)
- Myelin oligodendrocyte glycoprotein induces aquaporin-4 autoantibodies in mouse experimental autoimmune encephalomyelitis (2013) (4)
- Serotonergic dysfunctions and abnormal iron metabolism: Relevant to mental fatigue of Parkinson disease. (2016) (4)
- Primary familial brain calcifications linked with a novel SLC20A2 gene mutation in a Chinese family (2017) (4)
- The Prevalence and Clinical Characteristics of Essential Tremor in Elderly Chineses: A Population-Based Study (2020) (4)
- [Association between DLST gene polymorphism and Alzheimer's disease]. (2001) (4)
- Protocol for evaluation of perioperative risk in patients aged over 75 years: Aged Patient Perioperative Longitudinal Evaluation–Multidisciplinary Trial (APPLE-MDT study) (2021) (4)
- Hypomethylation of SNCA in Idiopathic REM Sleep Behavior Disorder Associated With Phenoconversion (2020) (4)
- Early morning off in patients with Parkinson’s disease: a Chinese nationwide study and a 7-question screening scale (2020) (4)
- Skeletal Muscle Metabolic Alternation Develops Sarcopenia (2022) (4)
- Validation of a new olfactory test for Chinese Parkinson’s disease patients (2020) (4)
- Circadian E-boxes and surrounding CpG islands are free from methylation throughout the day (2012) (3)
- Altered Functional Segregated Sensorimotor, Associative, and Limbic Cortical-Striatal Connections in Parkinson's Disease: An fMRI Investigation (2021) (3)
- Genetics of Parkinson's Disease (2007) (3)
- Striatal Subdivisions Estimated via Deep Embedded Clustering With Application to Parkinson's Disease (2021) (3)
- Change of olfactory function associated structures in Parkinson's disease:a voxel-based morphometry study (2011) (3)
- Postural Tremor Is Associated with Gait and Balance Impairments in Community‐Dwelling Older People (2019) (3)
- Exonic sequencing revealed no causative mutation in the BST1 gene in patients with Parkinson's disease (2013) (3)
- Musculoskeletal Pain in Parkinson's Disease (2022) (3)
- Parkinsonism with Normal Dopaminergic Presynaptic Terminals in Cerebrotendinous Xanthomatosis (2020) (3)
- The influence of probable rapid eye movement sleep behavior disorder and sleep insufficiency on fall risk in a community-dwelling elderly population (2021) (2)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (2)
- Calpastatin Gene (CAST) Is Not Associated with Late Onset Sporadic Parkinson’s Disease in the Han Chinese Population (2013) (2)
- Abnormal Spontaneous Neuronal Discharge and Local Field Potential both in Cortex and Striatum of a Non- human Primate of Parkinson’s Disease using Implantable Microelectrode Arrays (2018) (2)
- C-terminal part of alpha-synuclein mediates its activity in promoting proliferation of dopaminergic cells (2012) (2)
- Multimodal Data for the Detection of Freezing of Gait in Parkinson’s Disease (2022) (2)
- High-accuracy wearable detection of freezing of gait in Parkinson's disease based on pseudo-multimodal features. (2022) (2)
- Altered Cerebellar Resting-State Functional Connectivity in Early-Stage Parkinson's Disease Patients With Cognitive Impairment (2021) (2)
- Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson’s disease and dopaminergic neuron dysfunction (2021) (2)
- Criteria for Prodromal Parkinson ’ s Disease (2015) (2)
- Similarities and Differences in Cognitive Deficits and Responsiveness to L-Dopa between Aged and MPTP-Treated Cynomolgus Monkeys Tested on the Same Tasks (2014) (1)
- Oxidative DNA damage triggers ProNGF-Mediated apoptosis in the striatum of 6-OHDA-treated rats (2012) (1)
- Parkinson ’ s disease – related spatial covariance pattern identi fi ed with resting-state functional MRI (2017) (1)
- Progressive supranuclear palsy presenting with hyperkinetic movement disorder and hemiplegic dystonia: a case report (2020) (1)
- Mitochondrial alpha-synuclein: Implications in neurodegenerative diseases (2009) (1)
- Low-dose chloroquine treatment extends the lifespan of aged rats (2022) (1)
- Effect of dual-task interference on the hand flexibility of patients with Parkinson’s disease carrying the leucine-rich repeat kinase 2 gene mutation (2013) (1)
- Analysis of glucose metabolism in cynomolgus monkeys during aging (2011) (1)
- The tropism of embryoid body cells for glioma cells (2007) (1)
- Graph Theoretical Analysis of Semantic Fluency in Patients with Parkinson's Disease (2022) (1)
- COMPARISON OF FOUR RISK SCORING SYSTEMS FOR OLD PATIENTS: A PROSPECTIVE MULTICENTER STUDY IN CHINA. (2017) (1)
- Reply to the letter “Waist circumference or sarcopenic obesity; which is more predictive?” (2019) (1)
- Effects of cognitive ageing trajectories on multiple adverse outcomes among Chinese community-dwelling elderly population (2022) (1)
- Detection of Motor Dysfunction With Wearable Sensors in Patients With Idiopathic Rapid Eye Movement Disorder (2021) (1)
- Tracking Response Dynamics of Sequential Working Memory in Patients With Mild Parkinson’s Disease (2021) (1)
- α‐Synuclein aggregation causes muscle atrophy through neuromuscular junction degeneration (2022) (1)
- Impaired Formation and Expression of Goal-Directed and Habitual Control in Parkinson’s Disease (2021) (1)
- Diagnostic value of striatal 18F-FP-DTBZ PET in Parkinson’s disease (2022) (1)
- Apolipoprotein E Polymorphism and Frailty: Apolipoprotein ε4 Allele Is Associated with Fatigue but Not Frailty Syndrome in a Community-Dwelling Older Population Cohort (2020) (1)
- Functional localization in the brain of a cynomolgus monkey based on spike pattern recognition with machine learning (2019) (1)
- Physical Resilience: A novel approach for healthy aging (2022) (1)
- Changes of Amide Proton Transfer Imaging in Multiple System Atrophy Parkinsonism Type (2020) (1)
- MPTP Induces Systemic Parkinsonism in Middle-Aged Cynomolgus Monkeys: Clinical Evolution and Outcomes (2016) (1)
- Signi fi cance of the potential role of pharmacological MRI ( phMRI ) in diagnosis of Parkinson ’ s disease (0)
- Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population (2023) (0)
- NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy (2012) (0)
- Oxidative DNA damage triggers ProNGF-Mediated apoptosis in the striatum of 6-OHDA-treated rats (2012) (0)
- Ganoderma lucidum extract ameliorates MPTP-induced parkinsonism and protects dopaminergic neurons from oxidative stress via regulating mitochondrial function, autophagy, and apoptosis (2018) (0)
- Corrigendum: Diagnostic value of striatal 18F-FP-DTBZ PET in Parkinson's disease (2022) (0)
- Association between body fat and sarcopenia in older adults with type 2 diabetes mellitus: A cross-sectional study (2023) (0)
- 5-(4-Hydroxy-3-dimethoxybenzylidene)-thiazolidinone improves motor functions and exerts antioxidant potential in hemiparkinsonian rats (2022) (0)
- NIPA2 mutations are correlative with childhood absence epilepsy in the Han Chinese population (2014) (0)
- FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction (2020) (0)
- Convolutional Neural Network Optimize the Application of Diffusion Kurtosis Imaging in Parkinson’s Disease (2021) (0)
- The recommendations of Chinese Parkinson’s disease and movement disorder society consensus on therapeutic management of Parkinson’s disease (2016) (0)
- The underlying mechanism of prodromal PD: insights from the parasympathetic nervous system and the olfactory system (2017) (0)
- Biomarkers of aging (2023) (0)
- Author Correction: Altered resting-state brain activity in Parkinson’s disease patients with freezing of gait (2018) (0)
- ASSOCIATION OF SOCIAL FRAILTY WITH PHYSICAL FUNCTION AND NEUROPSYCHOLOGICAL STATUS AMONG OLDER ADULTS (2018) (0)
- Intrinsic capacity and healthy ageing. (2022) (0)
- C-terminal part of alpha-synuclein mediates its activity in promoting proliferation of dopaminergic cells (2012) (0)
- Ganoderma lucidum Modulates Inflammatory Responses following 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Administration in Mice (2022) (0)
- FACTORS ASSOCIATED WITH THE EXPRESSION OF HUMAN α-SYNUCLEIN GENE IN PROKARYOTIC CELLS (2002) (0)
- Patient-centred management of Parkinson's disease – Authors' reply (2020) (0)
- The most pressing issue of standardizing the preoperative assessment of deep brain stimulation (2017) (0)
- LRRK2 Cohort Consortium Investigator List (2016) (0)
- Relationship between smoking and olfactory dysfunction in Parkinson's disease (2017) (0)
- Fatigue in Patients with Idiopathic/Isolated REM Sleep Behavior Disorder (2022) (0)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (0)
- Restless legs syndrome in Parkinson disease: Clinical characteristics, abnormal iron metabolism and altered neurotransmitters (2017) (0)
- Progressive loss of striatal dopamine terminals in MPTP-induced acute parkinsonism in cynomolgus monkeys using vesicular monoamine transporter type 2 PET imaging ([18F]AV-133) (2013) (0)
- Practiced Movement Cerebellar Damage Impairs Automaticity of a Recently (2015) (0)
- Wrist attitude-based Parkinson's disease ON/OFF state assessment after medication (2021) (0)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (0)
- Parkinson Disease in Twins (2017) (0)
- Difference in Amyloid Load Between Single Memory Domain and Multidomain Subjective Cognitive Decline: A Study from the SILCODE. (2021) (0)
- Iron deposition in substantia nigra: abnormal iron metabolism, neuroinflammatory mechanism and clinical relevance (2017) (0)
- Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome (2018) (0)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (0)
- Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis (2021) (0)
- Age as a risk factor for orthostatic hypotension induced by the levodopa challenge test in patients with Parkinson’s disease: Results from a single-center trial (2023) (0)
- Significance of the potential role of pharmacological MRI (phMRI) in diagnosis of Parkinson’s disease (2012) (0)
- Chemical screen identifies a geroprotective role of quercetin in premature aging (2018) (0)
- Association between postural tremor and risk of disability in community‐dwelling older people (2022) (0)
- Early morning off in patients with Parkinson’s disease: a Chinese nationwide study and a 7-question screening scale (2020) (0)
- LRRK2-associated Parkinson's disease patients have better stereopsis than idiopathic Parkinson disease (2018) (0)
- Research on the Characteristics of Action Potentials and Local Field Potentials in Cortex of Parkinson's Disease Mode Monkey * (2020) (0)
- A Multi-Atlas-Based [18F]9-Fluoropropyl-(+)-Dihydrotetrabenazine Positron Emission Tomography Image Segmentation Method for Parkinson’s Disease Quantification (2022) (0)
- A single-cell transcriptomic landscape of primate arterial aging (2020) (0)
- An atypical ALS with PSP-like symptoms caused by ANXA11 p.D40G mutation: A case report and literature review (2023) (0)
- Parkinson disease with constipation: clinical features and relevant factors (2018) (0)
- ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells (2018) (0)
- Frequency-dependentNeural Activity in Parkinson’s Disease (2014) (0)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (0)
- Meta-analysis of clinical differences between Parkinson's disease patients with and without REM sleep behavior disorder (2013) (0)
- Attention must be paid to cognitive dysfunction in Parkinson's disease (2017) (0)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (0)
- Gene symbol: ATP7B. Disease: Wilson's disease. (2005) (0)
- 2.002 PRECLINICAL TO CLINICAL NEURAL CHANGES IN PARKINSON'S DISEASE (2012) (0)
- Olfactory Dysfunction in Parkinson’s Disease Patients with the LRRK2 G2385R Variant (2016) (0)
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What Schools Are Affiliated With Piu Chan?
Piu Chan is affiliated with the following schools:
