Shirley M. Tilghman | Academic Influence

Shirley M. Tilghman's AcademicInfluence.com Rankings

Shirley M. Tilghman

Biology

#605

World Rank

#1071

Historical Rank

Molecular Biology

#192

World Rank

#196

Historical Rank

biology Degrees

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Biology

Shirley M. Tilghman's Degrees

Bachelors Chemistry Queen's University at Kingston

Why Is Shirley M. Tilghman Influential?

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According to Wikipedia, Shirley Marie Tilghman, is a Canadian scholar in molecular biology and an academic administrator. She is now a professor of molecular biology and public policy and president emerita of Princeton University. In 2002, Discover magazine recognized her as one of the 50 most important women in science.

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Shirley M. Tilghman's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus (2000) (1532)
Parental imprinting of the mouse H19 gene (1991) (1185)
The product of the H19 gene may function as an RNA (1990) (1040)
The Mouse Fused Locus Encodes Axin, an Inhibitor of the Wnt Signaling Pathway That Regulates Embryonic Axis Formation (1997) (944)
Genomic imprinting in mammals. (1997) (816)
Disruption of imprinting caused by deletion of the H19 gene region in mice (1995) (804)
Scientific Teaching (2004) (715)
Rescuing US biomedical research from its systemic flaws (2014) (640)
The Sins of the Fathers and Mothers Genomic Imprinting in Mammalian Development (1999) (519)
Epigenetic mechanisms underlying the imprinting of the mouse H19 gene. (1993) (512)
Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes. (2006) (457)
Glyceroneogenesis and the Triglyceride/Fatty Acid Cycle* (2003) (441)
A paternal–specific methylation imprint marks the alleles of the mouse H19 gene (1995) (440)
An enhancer deletion affects both H19 and Igf2 expression. (1995) (425)
Genomic imprinting of Mash2, a mouse gene required for trophoblast development (1995) (388)
The temporal requirement for endothelin receptor-B signalling during neural crest development (1999) (349)
Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes. (1997) (343)
CTCF maintains differential methylation at the Igf2/H19 locus (2003) (339)
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. (2000) (321)
The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites (1978) (284)
Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes. (1984) (282)
Physical linkage of two mammalian imprinted genes, H19 and insulin–like growth factor 2 (1992) (275)
Transcriptional control of the murine albumin/alpha-fetoprotein locus during development. (1982) (270)
Multiple Mechanisms Regulate Imprinting of the Mouse Distal Chromosome 7 Gene Cluster (1998) (261)
The structure and expression of a novel gene activated in early mouse embryogenesis. (1988) (240)
Diversity of alpha-fetoprotein gene expression in mice is generated by a combination of separate enhancer elements. (1987) (239)
Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene. (1978) (198)
Allelic expression of IGF2 in marsupials and birds (2000) (193)
Genomic imprinting is disrupted in interspecific Peromyscus hybrids (1998) (185)
Genetic and epigenetic incompatibilities underlie hybrid dysgenesis in Peromyscus (2000) (178)
Ectopic expression of the H19 gene in mice causes prenatal lethality. (1991) (173)
Multiple regulatory elements in the intergenic region between the alpha-fetoprotein and albumin genes (1986) (170)
Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome. (1999) (170)
Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences. (1977) (161)
Two dominant mutations in the mouse fused gene are the result of transposon insertions. (1997) (161)
The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor. (1978) (158)
A mutation in the peroxisome proliferator-activated receptor γ-binding site in the gene for the cytosolic form of phosphoenolpyruvate carboxykinase reduces adipose tissue size and fat content in mice (2002) (145)
A differentially methylated region within the gene Kcnq1 functions as an imprinted promoter and silencer. (2003) (143)
The evolution of alpha-fetoprotein and albumin. II. The structures of the alpha-fetoprotein and albumin genes in the mouse. (1981) (139)
Piebald lethal (sl) acts early to disrupt the development of neural crest-derived melanocytes. (1994) (138)
Purification and cloning of a mouse ribosomal gene fragment in coliphage lambda. (1977) (135)
Location of enhancers is essential for the imprinting of H19 and Igf2 genes (1998) (134)
Dosage requirement and allelic expression of PAX6 during lens placode formation. (2000) (134)
Genetic analysis of alpha-fetoprotein synthesis in mice (1982) (122)
Clock regulatory elements control cyclic expression of Lunatic fringe during somitogenesis. (2002) (120)
Two regulatory domains flank the mouse H19 gene (1988) (117)
Dominant negative regulation of the mouse alpha-fetoprotein gene in adult liver. (1990) (117)
Tissue-specific transcription of the mouse alpha-fetoprotein gene promoter is dependent on HNF-1 (1989) (117)
Statement on use of DNA testing for presymptomatic identification of cancer risk. National Advisory Council for Human Genome Research. (1994) (115)
Developmental regulation of alpha-fetoprotein genes in transgenic mice (1985) (112)
The evolution of alpha-fetoprotein and albumin. I. A comparison of the primary amino acid sequences of mammalian alpha-fetoprotein and albumin. (1981) (111)
Multiple related immunoglobulin variable-region genes identified by cloning and sequence analysis. (1978) (111)
Phosphoenolpyruvate carboxykinase and the critical role of cataplerosis in the control of hepatic metabolism (2005) (110)
Igf2 imprinting does not require its own DNA methylation or H19 RNA. (1998) (107)
Enhancer competition between H19 and Igf2 does not mediate their imprinting. (1999) (107)
Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and trans. (1997) (107)
Fine-structure mapping of the three mouse alpha-fetoprotein gene enhancers (1988) (105)
Phenotypic and molecular analysis of a transgenic insertional allele of the mouse Fused locus. (1995) (102)
Exploring genome space (2000) (102)
A comparison of two cloned mouse β-globin genes and their surrounding and intervening sequences (1978) (102)
The structural H19 gene is required for transgene imprinting. (1996) (99)
Rapid loss of translatable messenger RNA of phosphoenolpyruvate carboxykinase during glucose repression in liver. (1974) (92)
alpha-Fetoprotein and albumin genes are in tandem in the mouse genome. (1981) (91)
Chromatin conformation of the H19 epigenetic mark. (1998) (89)
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia. (2001) (89)
Gatm, a creatine synthesis enzyme, is imprinted in mouse placenta (2003) (86)
Tissue-specific activation of a cloned α-fetoprotein gene during differentiation of a transfected embryonal carcinoma cell line (1984) (85)
Intragenic amplification and divergence in the mouse α-fetoprotein gene (1981) (85)
Deletion of a nuclease-sensitive region between the Igf2 and H19 genes leads to Igf2 misregulation and increased adiposity. (2001) (80)
Genetic and Physical Mapping (1990) (80)
Postnatal repression of the alpha-fetoprotein gene is enhancer independent. (1989) (78)
Induction of alpha-fetoprotein synthesis in differentiating F9 teratocarcinoma cells is accompanied by a genome-wide loss of DNA methylation (1984) (73)
A G → A substitution in an HNF I binding site in the human α-fetoprotein gene is associated with hereditary persistence of α-fetoprotein (HPAFP) (1993) (72)
An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina. (2003) (72)
Effects of cyclic adenosine monophosphate, dexamethasone and insulin on phosphoenolpyruvate carboxykinase synthesis in Reuber H-35 hepatoma cells. (1975) (65)
The ontogeny of alpha-fetoprotein gene expression in the mouse gastrointestinal tract (1990) (64)
Characterization and biological activity of cloned simian virus 40 DNA fragments. (1981) (59)
Differential expression of α-fetoprotein genes on the inactive X chromosome in extraembryonic and somatic tissues of a transgenic mouse line (1986) (58)
The structure and regulation of the alpha-fetoprotein and albumin genes. (1985) (55)
Disruption of an imprinted gene cluster by a targeted chromosomal translocation in mice (2001) (54)
Role of alpha-fetoprotein regulatory elements in transcriptional activation in transient heterokaryons (1990) (54)
Allele-specific gene expression in mammals: the curious case of the imprinted RNAs. (1994) (53)
Construction and expression in vivo of an internally deleted mouse alpha-fetoprotein gene: presence of a transcribed Alu-like repeat within the first intervening sequence. (1982) (53)
Murineα-fetoprotein and albumin: Two evolutionarily linked proteins encoded on the same mouse chromosome (1981) (50)
Expression and Functional Analysis ofUch-L3 during Mouse Development (2000) (48)
Genomic imprinting in mice: its function and mechanism. (1996) (48)
Opinion: Addressing systemic problems in the biomedical research enterprise (2015) (48)
Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts. (1992) (47)
Increasing gender diversity in the STEM research workforce (2019) (46)
Quantitative trait loci that modify the severity of spotting in piebald mice. (1995) (46)
Transcriptional control of the murine albumin / a-fetoprotein locus during development ( RNA hybridization / developing liver / differentiation / modulation ) (46)
Transient expression of a mouse alpha-fetoprotein minigene: deletion analyses of promoter function (1983) (45)
Alterations in translatable messenger RNA coding for phosphoenolpyruvate carboxykinase (GTP) in rat liver cytosol during deinduction. (1978) (45)
Fine structure mapping and deletion analysis of the murine piebald locus. (1994) (42)
Evolution of the albumin: alpha-fetoprotein ancestral gene from the amplification of a 27 nucleotide sequence. (1984) (41)
Construction and cloning of rat albumin structural gene sequences. (1979) (41)
Structure and developmental expression of the chick α-actin gene (1980) (41)
The presence of intervening sequences in the alpha-fetoprotein gene of the mouse. (1979) (41)
Molecular biology of the W and steel loci. (1991) (41)
Functional analyses of albumin expression in a series of hepatocyte cell lines and in primary hepatocytes. (1992) (40)
Phosphoenolpyruvate carboxykinase revisited: Insights into its metabolic role (2002) (38)
Complementation mapping of skeletal and central nervous system abnormalities in mice of the piebald deletion complex. (1996) (38)
Molecular analysis of the distal enhancer of the mouse alpha-fetoprotein gene (1995) (37)
raf regulates the postnatal repression of the mouse alpha-fetoprotein gene at the posttranscriptional level (1992) (36)
Genomic imprinting of a placental lactogen gene in Peromyscus (2001) (34)
Configuration of the alpha-fetoprotein regulatory domain during development. (1988) (33)
Structure of the alpha-fetoprotein gene in the mouse. (1980) (27)
The cloning of mouse globin and surrounding gene sequences in bacteriophage lambda. (1978) (27)
Nondisjunction rates and abnormal embryonic development in a mouse cross between heterozygotes carrying a (7, 18) robertsonian translocation chromosome. (1995) (26)
A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP). (1993) (26)
Regulated Expression of α-Fetoprotein Genes in Transgenic Mice (1985) (26)
The Sequence of the Chromosomal Mouse /3-Globin Major Gene: Homologies in Capping, Splicing and (1978) (25)
Concrete steps to diversify the scientific workforce (2021) (24)
Deinduction of phosphoenolpyruvate carboxykinase (guanosine triphosphate) synthesis in Reuber H-35 cells. (1975) (24)
Parental imprinting of the H19 and Igf2 genes in the mouse. (1993) (24)
Molecular characterization of four induced alleles at the Ednrb locus. (1997) (24)
Parental imprinting in the mouse. (1991) (24)
Raf, a trans-acting locus, regulates the alpha-fetoprotein gene in a cell-autonomous manner. (1987) (24)
The zonal expression of α‐fetoprotein transgenes in the livers of adult mice (1992) (24)
A human H19 transgene exhibits impaired paternal-specific imprint acquisition and maintenance in mice. (2002) (23)
Regulation of pyruvate metabolism via pyruvate carboxylase in rat brain mitochondria. (1973) (23)
Candidate genes required for embryonic development: a comparative analysis of distal mouse chromosome 14 and human chromosome 13q22. (2002) (23)
Spatially restricted hypopigmentation associated with an Ednrbs-modifying locus on mouse chromosome 10. (2000) (22)
The Developmental Regulation of Albumin and α-Fetoprotein Gene Expression (1989) (22)
Structure and expression of the mouse L23mrp gene downstream of the imprinted H19 gene: biallelic expression and lack of interaction with the H19 enhancers. (1997) (20)
Optimizing the detection of nascent transcripts by RNA fluorescence in situ hybridization. (2001) (19)
Molecular cloning of developmentally regulated, low-abundance mRNA sequences from embryonic muscle. (1980) (19)
Lessons learned, promises kept: a biologist's eye view of the Genome Project. (1996) (18)
Competitive edge at the imprinted Prader-Willi/Angelman region? (1998) (18)
DNA methylation: a phoenix rises. (1993) (17)
Functional Characterization of a Testis-Specific DNA Binding Activity at the H19/Igf2 Imprinting Control Region (2003) (17)
Functional Characterization of a Novel Ku70/80 Pause Site at the H19/Igf2 Imprinting Control Region (2005) (17)
Expression and Functional Analysis of Uch-L3 during Mouse Development (2000) (16)
A mouse genomic library of yeast artificial chromosome clones (2004) (14)
Synthesis of phosphoenolpyruvate carboxykinase (guanosine triphosphate) by isolated liver polyribosomes. (1974) (13)
Differential requirements for cellular enhancers in stem and differentiated cells. (1988) (13)
Configuration of the a-fetoprotein regulatory domain during aevelopment (1988) (11)
Hereditary persistence of alpha fetoprotein maps to the long arm of chromosome 4 (1985) (11)
Genes and phenotypes. (1991) (10)
Genetic map of the fused locus on mouse chromosome 17. (1994) (10)
The Absence of Enhancer Competition betweenIgf2 and H19 following Transfer into Differentiated Cells (1998) (10)
Monoallelic expression of reactivated imprinted genes in embryonal carcinoma cell hybrids. (1999) (9)
Genome maps and neurological disorders (1993) (9)
The zonal expression of alpha-fetoprotein transgenes in the livers of adult mice. (1992) (8)
Becoming more transparent: Collecting and presenting data on biomedical Ph.D. alumni (2018) (8)
Genetic Analysis of oc-Fetoprotein Synthesis in Mice (2003) (8)
Structural studies on oncornavirus-related sequences in chicken genomic DNA: two-step analyses of EcoRI and Bgl I restriction digests and tentative mapping of a ubiquitous endogenous provirus digests and tentative mapping of a ubiquitous endogenous provirus. (1979) (7)
Genome rearrangement and stability (1995) (7)
Improving support for young biomedical scientists (2018) (7)
The activation and silencing of gene transcription in the liver. (1991) (7)
The developmental regulation of albumin and alpha-fetoprotein gene expression. (1989) (7)
Fine-Structure Mapping of the Three Mouse ox-Fetoprotein Gene Enhancers (2003) (6)
Tissue-Specific Transcription oftheMouseoL-Fetoprotein Gene Promoter IsDependent on HNF-1 (1989) (6)
Cloning specific segments ofthemammalian genome: Bacteriophage Xcontaining mouseglobin andsurrounding genesequences (1977) (6)
Intragenic amplification and divergence in the mouse alpha-fetoprotein gene. (1981) (5)
Transgenic Mice: Gene Transfer into the Germ Line (1986) (5)
Gene expression and its control (1991) (5)
Not just Salk (2017) (5)
Locus unlinked to o-fetoprotein under the control of the murine raf and Rif genes ( regulatory genes / tissue specificity / cDNA cloning / developmental regulation ) VASSILIS PACHNIS (4)
Regulated expression of alpha-fetoprotein genes in transgenic mice. (1985) (4)
Expanding equal opportunity: The Princeton experience with financial aid (2007) (4)
Structure of the a-fetoprotein gene in the mouse (3)
Epigenetic Reprogramming in Mammalian Development (2001) (3)
Strategies for physical mapping (1992) (3)
Partial isolation and translation in vitro of messenger ribonucleic acid for phosphoenolpyruvate carboxykinase (guanosine triphosphate). (1976) (3)
2015 ASCB Annual Meeting abstracts (2015) (2)
The mouse t complex responder locus. (1991) (2)
THE CLONING OF A SPECIFIC SEGMENT OF THE HAMSTER GENOME REQUIRED FOR CELL PROLIFERATION * (1982) (1)
No money, no research (2014) (1)
Linkage between vitamin D-binding protein and alpha-fetoprotein in the mouse. (1996) (1)
Linkage between vitamin D-binding protein and α-fetoprotein in the mouse (2009) (1)
A silencer regulates the expression of the mouse α-fetoprotein gene in adult liver (1989) (1)
Twists and turns: a scientific journey. (2014) (1)
Structure and developmental expression of the chick alpha-actin gene. (1980) (1)
The regulation of alpha-foetoprotein minigene expression in the germline of mice. (1986) (1)
Genetic and physical mapping. Volume 1. Genome analysis. (1990) (1)
Richard Winfield Hanson (1936–2014) (2014) (0)
Structure of the a-fetoprotein gene (genomic library/cloning/restriction mapping/electron microscop (2016) (0)
Use of an EK-2 vector for the cloning of DNA from higher organisms. (1978) (0)
This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected on April 30 , 1996 . The structural H 19 gene is required for transgene imprinting (1996) (0)
Should the Endless Frontier of Federal Science be Expanded? (2021) (0)
Shirley Tilghman, PhD. (2002) (0)
Genetic analysis of multifactorial disease: lessons from type-1 diabetes. (1991) (0)
Reply to Schumacher et al. (1998) (0)
Marie Curie Nobel Centenary. (2003) (0)
Bridging the Gender Gap in Science and Technology (2010) (0)
A Gem of a Collection (2010) (0)
It's All about the Talent (2010) (0)
TheProduct oftheH19GeneMayFunction as an RNA (1990) (0)
rafRegulates thePostnatal Repression oftheMouseot-Fetoprotein GeneatthePosttranscriptio nal (1992) (0)
Regional Physical Mapping (1993) (0)
Studies into the raf and Rif genes in the mouse. (1985) (0)
How the US can best support the careers of promising young biomedical scientists (2018) (0)
The making of a President: an interview with Shirley Tilghman. Interview by Jane Gitschier. (2006) (0)
Tissue-Specific Transcription of the Mouse oL-Fetoprotein Gene Promoter (0)
Intervening sequence ofDNA identified inthestructural portion of amousefl-globin gene (1978) (0)
Erratum: Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and trans (Proceedings of the National Academy of Sciences of the USA (September 16, 1997) 19 (10243-10248)) (1997) (0)
Profile of Bruce M. Alberts, 2016 Lasker-Koshland Special Achievement Award in Medical Science Awardee (2017) (0)
In Memorium, Philip Leder (1934–2020) (2020) (0)
Interview with president Shirley Tilghman (Princeton University). (2008) (0)
The regulation of α-foetoprotein minigene expression in the germline of mice (1986) (0)
o-Fetoprotein Minigene: Deletion Analyses of Promoter Function (2003) (0)
“Players and painted stage took all my love”: The Leonard L. Milberg; Irish Theater Collection (2007) (0)

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