Susan Lindquist | Academic Influence

Why Is Susan Lindquist Influential?

According to Wikipedia, Susan Lee Lindquist, ForMemRS was an American professor of biology at MIT specializing in molecular biology, particularly the protein folding problem within a family of molecules known as heat-shock proteins, and prions. Lindquist was a member and former director of the Whitehead Institute and was awarded the National Medal of Science in 2010.

Susan Lindquist's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Papers

The heat-shock proteins. (3905)
The heat-shock response. (3649)
HSP90 and the chaperoning of cancer (2215)
The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins. (2167)
Hsp90 as a capacitor for morphological evolution (2122)
HSP90 at the hub of protein homeostasis: emerging mechanistic insights (1494)
Hsp104, Hsp70, and Hsp40 A Novel Chaperone System that Rescues Previously Aggregated Proteins (1288)
Hsp90 as a capacitor of phenotypic variation (1283)
α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models (1233)
Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+]. (985)
Nucleated conformational conversion and the replication of conformational information by a prion determinant. (920)
The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome (878)
Protein disaggregation mediated by heat-shock protein Hspl04 (870)
A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins (825)
HSP104 required for induced thermotolerance. (800)
Heat Shock Factor 1 Is a Powerful Multifaceted Modifier of Carcinogenesis (767)
Reduced levels of hsp90 compromise steroid receptor action in vivo (750)
Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology (750)
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition (659)
A yeast prion provides a mechanism for genetic variation and phenotypic diversity (653)
Heat Shock Protein 101 Plays a Crucial Role in Thermotolerance in Arabidopsis (639)
hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures. (637)
Multiple effects of trehalose on protein folding in vitro and in vivo. (633)
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations (630)
Conducting nanowires built by controlled self-assembly of amyloid fibers and selective metal deposition (616)
HSP100/Clp proteins: a common mechanism explains diverse functions. (604)
Support for the Prion Hypothesis for Inheritance of a Phenotypic Trait in Yeast (604)
Hsp90 Potentiates the Rapid Evolution of New Traits: Drug Resistance in Diverse Fungi (581)
Self-Seeded Fibers Formed by Sup35, the Protein Determinant of [PSI +], a Heritable Prion-like Factor of S. cerevisiae (564)
Hsp104 is required for tolerance to many forms of stress. (557)
HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers (547)
A Neuronal Isoform of the Aplysia CPEB Has Prion-Like Properties (527)
Aggregation of huntingtin in yeast varies with the length of the polyglutamine expansion and the expression of chaperone proteins. (513)
Heat Shock (507)
Prions as adaptive conduits of memory and inheritance (504)
Neurotoxicity and Neurodegeneration When PrP Accumulates in the Cytosol (486)
α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity (482)
RNA splicing is interrupted by heat shock and is rescued by heat shock protein synthesis (477)
The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels (472)
Rnq1: an epigenetic modifier of protein function in yeast. (468)
Hsp104 Catalyzes Formation and Elimination of Self-Replicating Sup35 Prion Conformers (461)
Thermotolerance in Saccharomyces cerevisiae: the Yin and Yang of trehalose. (460)
Structural insights into a yeast prion illuminate nucleation and strain diversity (450)
α-Synuclein: membrane interactions and toxicity in Parkinson's disease. (441)
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis (429)
Increase in Activity During Calorie Restriction Requires Sirt1 (418)
Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase (417)
A suite of Gateway® cloning vectors for high‐throughput genetic analysis in Saccharomyces cerevisiae (413)
Heat-shock protein hsp90 governs the activity of pp60v-src kinase. (409)
Regulation of protein synthesis during heat shock (392)
Yeast Genes That Enhance the Toxicity of a Mutant Huntingtin Fragment or α-Synuclein (392)
Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders (386)
The consequences of expressing hsp70 in Drosophila cells at normal temperatures. (386)
Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. (382)
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity (381)
Identification and Rescue of α-Synuclein Toxicity in Parkinson Patient–Derived Neurons (380)
hsp70: Nuclear concentration during environmental stress and cytoplasmic storage during recovery (369)
In vivo functions of the Saccharomyces cerevisiae Hsp90 chaperone. (366)
Prions are a common mechanism for phenotypic inheritance in wild yeasts (361)
Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. (349)
Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer’s Disease Risk Factors in Yeast (338)
Epigenetic regulation of translation reveals hidden genetic variation to produce complex traits (331)
Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease (324)
Varying patterns of protein synthesis in Drosophila during heat shock: implications for regulation. (317)
A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways (313)
Conversion of PrP to a Self-Perpetuating PrPSc-like Conformation in the Cytosol (311)
Hsp90 and Environmental Stress Transform the Adaptive Value of Natural Genetic Variation (305)
Cryptic Variation in Morphological Evolution: HSP90 as a Capacitor for Loss of Eyes in Cavefish (294)
Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation (293)
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity (292)
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis. (288)
Widespread regulation of translation by elongation pausing in heat shock. (287)
18 Heat Shock Proteins and Stress Tolerance (285)
A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures (284)
Flanking sequences profoundly alter polyglutamine toxicity in yeast. (282)
Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. (276)
An ancient developmental induction: heat-shock proteins induced in sporulation and oogenesis. (268)
A Chaperone Pathway in Protein Disaggregation (266)
Hspl04 is a highly conserved protein with two essential nucleotide-binding sites (264)
Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis. (259)
The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy (254)
Transgenerational epigenetic inheritance: how important is it? (248)
High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer (248)
Prion Switching in Response to Environmental Stress (246)
Under cover: causes, effects and implications of Hsp90‐mediated genetic capacitance (245)
Mapping differential interactomes by affinity purification coupled with data independent mass spectrometry acquisition (243)
The preferential translation of Drosophila hsp70 mRNA requires sequences in the untranslated leader (242)
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal (239)
Chaperone-supervised conversion of prion protein to its protease-resistant form. (237)
Role of the protein chaperone YDJ1 in establishing Hsp90-mediated signal transduction pathways. (237)
Mechanisms of protein-folding diseases at a glance (234)
PLAAC: a web and command-line application to identify proteins with prion-like amino acid composition (233)
Prions as protein-based genetic elements. (233)
Antagonistic Interactions between Yeast Chaperones Hsp104 and Hsp70 in Prion Curing (232)
Yeast genes that enhance the toxicity of a mutant huntingtin fragment or alpha-synuclein. (231)
A Cyclophilin Function in Hsp90-Dependent Signal Transduction (228)
Heat-shock protein 104 expression is sufficient for thermotolerance in yeast. (224)
Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State (222)
Effect of engineering Hsp70 copy number on Hsp70 expression and tolerance of ecologically relevant heat shock in larvae and pupae of Drosophila melanogaster. (220)
Hsp26 is not required for growth at high temperatures, nor for thermotolerance, spore development, or germination (218)
Yeast Reveal a “Druggable” Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons (216)
In vivo analysis of the Hsp90 cochaperone Sti1 (p60) (215)
The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication (214)
Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast? (213)
Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro. (213)
Destruction or potentiation of different prions catalyzed by similar Hsp104 remodeling activities. (211)
The role of heat-shock proteins in thermotolerance. (208)
Cdc37 is a molecular chaperone with specific functions in signal transduction. (208)
Epigenetics in the Extreme: Prions and the Inheritance of Environmentally Acquired Traits (205)
Hyperthermia protects mice against the lethal effects of endotoxin. (204)
Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B (196)
Oligopeptide-repeat expansions modulate ‘protein-only’ inheritance in yeast (190)
The role of Sis1 in the maintenance of the [RNQ+] prion (190)
Saccharomyces cerevisiae Hsp104 protein. Purification and characterization of ATP-induced structural changes. (188)
Cooperative kinetics of both Hsp104 ATPase domains and interdomain communication revealed by AAA sensor‐1 mutants (185)
Heat shock and recovery are mediated by different translational mechanisms. (184)
Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. (183)
HSP90 affects the expression of genetic variation and developmental stability in quantitative traits (181)
Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90. (181)
Hsp104, Hsp70 and Hsp40 interplay regulates formation, growth and elimination of Sup35 prions (179)
A Yeast Model of FUS/TLS-Dependent Cytotoxicity (178)
Interactions among alpha-synuclein, dopamine, and biomembranes: some clues for understanding neurodegeneration in Parkinson's disease. (177)
Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease. (175)
SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones (172)
An Arabidopsis heat shock protein complements a thermotolerance defect in yeast. (171)
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models (171)
Protein homeostasis and the phenotypic manifestation of genetic diversity: principles and mechanisms. (169)
Screening for Amyloid Aggregation by Semi-Denaturing Detergent-Agarose Gel Electrophoresis (167)
The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases (164)
Asymmetric deceleration of ClpB or Hsp104 ATPase activity unleashes protein-remodeling activity (163)
Is the major Drosophila heat shock protein present in cells that have not been heat shocked? (163)
Chemical and biological approaches for adapting proteostasis to ameliorate protein misfolding and aggregation diseases: progress and prognosis. (162)
Creating a protein-based element of inheritance. (161)
A new method for manipulating transgenes: engineering heat tolerance in a complex, multicellular organism (160)
Chaperone-dependent amyloid assembly protects cells from prion toxicity (156)
Inactivation of the ampD gene causes semiconstitutive overproduction of the inducible Citrobacter freundii beta-lactamase (155)
Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion (155)
Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiae. (155)
Phenotypic Diversity and Altered Environmental Plasticity in Arabidopsis thaliana with Reduced Hsp90 Levels (154)
Mad Cows Meet Psi-chotic Yeast: The Expansion of the Prion Hypothesis (153)
Prions, protein homeostasis, and phenotypic diversity. (152)
A heritable switch in carbon source utilization driven by an unusual yeast prion. (150)
Opposing effects of glutamine and asparagine govern prion formation by intrinsically disordered proteins. (148)
Widespread inhibition of posttranscriptional splicing shapes the cellular transcriptome following heat shock. (147)
Locus-specific control of asymmetric and CpNpG methylation by the DRM and CMT3 methyltransferase genes (146)
Inhibiting the transcription factor HSF1 as an anticancer strategy (146)
Intracellular localization of heat shock proteins in Drosophila (146)
A network of protein interactions determines polyglutamine toxicity. (146)
Changes in the middle region of Sup35 profoundly alter the nature of epigenetic inheritance for the yeast prion [PSI+] (144)
Changes in hsp70 alter thermotolerance and heat-shock regulation in Drosophila. (144)
Genetic Architecture of Hsp90-Dependent Drug Resistance (142)
Binding of the Citrobacter freundii AmpR regulator to a single DNA site provides both autoregulation and activation of the inducible ampC beta-lactamase gene (142)
Prion recognition elements govern nucleation, strain specificity and species barriers (140)
RNA metabolism: strategies for regulation in the heat shock response. (140)
Intrinsically Disordered Proteins Drive Emergence and Inheritance of Biological Traits (134)
Genetic evidence for a functional relationship between Hsp104 and Hsp70 (132)
Heat shock proteins affect RNA processing during the heat shock response of Saccharomyces cerevisiae. (129)
Blessings in disguise: biological benefits of prion-like mechanisms. (129)
The ATPase Activity of Hsp104, Effects of Environmental Conditions and Mutations* (129)
Atypical AAA+ Subunit Packing Creates an Expanded Cavity for Disaggregation by the Protein-Remodeling Factor Hsp104 (129)
Using the heat-shock response to discover anticancer compounds that target protein homeostasis. (128)
HSP90-buffered genetic variation is common in Arabidopsis thaliana (128)
Amyloid deposits: Protection against toxic protein species? (127)
Clioquinol promotes the degradation of metal-dependent amyloid-β (Aβ) oligomers to restore endocytosis and ameliorate Aβ toxicity (126)
Strains of [PSI+] are distinguished by their efficiencies of prion‐mediated conformational conversion (126)
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells (126)
Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein. (125)
Genetic analysis of viable Hsp90 alleles reveals a critical role in Drosophila spermatogenesis. (123)
Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis. (122)
Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism (122)
Spontaneous Generation of Prion Infectivity in Fatal Familial Insomnia Knockin Mice (119)
The Prion Protein Knockout Mouse (118)
Heat-shock proteins Hsp104 and Hsp70 reactivate mRNA splicing after heat inactivation (117)
The yeast non‐Mendelian factor [ETA+] is a variant of [PSI+], a prion‐like form of release factor eRF3 (114)
Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. (111)
The Drosophila hsp70 message is rapidly degraded at normal temperatures and stabilized by heat shock. (111)
Prion induction involves an ancient system for the sequestration of aggregated proteins and heritable changes in prion fragmentation (111)
Regulation of HSP70 synthesis by messenger RNA degradation. (110)
De novo generation of a PrPSc-like conformation in living cells (109)
Dominant gain-of-function mutations in Hsp104p reveal crucial roles for the middle region. (109)
Plasmodium falciparum heat shock protein 110 stabilizes the asparagine repeat-rich parasite proteome during malarial fevers. (108)
Conserved features of intermediates in amyloid assembly determine their benign or toxic states (108)
The elongation of yeast prion fibers involves separable steps of association and conversion. (108)
Luminidependens (LD) is an Arabidopsis protein with prion behavior (105)
Chaperones as thermodynamic sensors of drug–target interactions reveal kinase inhibitor specificities in living cells (104)
AmpG, a signal transducer in chromosomal β‐lactamase induction (104)
Translational efficiency of heat-induced messages in Drosophila melanogaster cells. (104)
Motor Mechanism for Protein Threading through Hsp104 (104)
[PSI+]: an epigenetic modulator of translation termination efficiency. (103)
FLP-mediated DNA mobilization to specific target sites in Drosophila chromosomes. (103)
Analysis of prion factors in yeast. (103)
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. (102)
Polyamine pathway contributes to the pathogenesis of Parkinson disease (99)
Translation of unspliced transcripts after heat shock. (98)
Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease (97)
The role of conformational flexibility in prion propagation and maintenance for Sup35p (97)
Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. (97)
Identification of SSF1, CNS1, and HCH1 as multicopy suppressors of a Saccharomyces cerevisiae Hsp90 loss-of-function mutation. (97)
Sensitivity-Enhanced NMR Reveals Alterations in Protein Structure by Cellular Milieus (96)
hsp26 of Saccharomyces cerevisiae is related to the superfamily of small heat shock proteins but is without a demonstrable function. (96)
HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models (95)
Interactions of the chaperone Hsp104 with yeast Sup35 and mammalian PrP. (92)
Rapid Selection of Cyclic Peptides that Reduce α-Synuclein Toxicity in Yeast and Animal Models (91)
HSP90 Shapes the Consequences of Human Genetic Variation (89)
Prion protein gene polymorphisms in Saccharomyces cerevisiae (88)
Inhibiting the transcription factor HSF1 as an anticancer strategy. (85)
Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+] (84)
Protein-only mechanism induces self-perpetuating changes in the activity of neuronal Aplysia cytoplasmic polyadenylation element binding protein (CPEB) (84)
Protein folding sculpting evolutionary change. (83)
An Evolutionarily Conserved Prion-like Element Converts Wild Fungi from Metabolic Specialists to Generalists (82)
Inhibition of heat shock protein synthesis by heat-inducible antisense RNA. (82)
Calcineurin determines toxic versus beneficial responses to α-synuclein (81)
ResponseNet: revealing signaling and regulatory networks linking genetic and transcriptomic screening data (81)
Selective translation and degradation of heat-shock messenger RNAs in Drosophila. (81)
BETASCAN: Probable β-amyloids Identified by Pairwise Probabilistic Analysis (80)
Changing patterns of gene expression during sporulation in yeast. (80)
Protein-only inheritance in yeast: something to get [PSI+]-ched about. (80)
Characterization of an HSP70 Cognate Gene Family in Arabidopsis. (79)
Signalling proteins in enterobacterial AmpC β‐lactamase regulation (79)
Bidirectional amyloid fiber growth for a yeast prion determinant (79)
Subunit interactions influence the biochemical and biological properties of Hsp104. (77)
Heat-shock proteins and stress tolerance in microorganisms (77)
Yeast prion [psi +] and its determinant, Sup35p. (77)
Hsp110 Chaperones Regulate Prion Formation and Propagation in S. cerevisiae by Two Discrete Activities (75)
The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration (72)
Eukaryotic initiation factor 4D, the hypusine-containing protein, is conserved among eukaryotes. (72)
Heat-shock proteins and stress tolerance in microorganisms. (71)
Analysis of the AAA sensor-2 motif in the C-terminal ATPase domain of Hsp104 with a site-specific fluorescent probe of nucleotide binding (71)
Autoregulation of the Heat-Shock Response (71)
The intracellular location of yeast heat-shock protein 26 varies with metabolism (69)
Different 8-Hydroxyquinolines Protect Models of TDP-43 Protein, α-Synuclein, and Polyglutamine Proteotoxicity through Distinct Mechanisms* (69)
Distinct prion strains are defined by amyloid core structure and chaperone binding site dynamics. (68)
Inhibiting GPI anchor biosynthesis in fungi stresses the endoplasmic reticulum and enhances immunogenicity. (67)
Maintenance and inheritance of yeast prions. (66)
Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease (66)
Prion formation by a yeast GLFG nucleoporin (65)
In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. (65)
Harnessing Natural Diversity to Probe Metabolic Pathways (64)
Biochemical, cell biological, and genetic assays to analyze amyloid and prion aggregation in yeast. (63)
Toward stem cell-based phenotypic screens for neurodegenerative diseases (62)
Lymphotoxin-dependent prion replication in inflammatory stromal cells of granulomas. (60)
Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs (57)
Structure-activity relationships for withanolides as inducers of the cellular heat-shock response. (57)
Non-toxic antimicrobials that evade drug resistance (56)
Preferential deadenylation of Hsp70 mRNA plays a key role in regulating Hsp70 expression in Drosophila melanogaster. (56)
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity (55)
A method for probing the mutational landscape of amyloid structure (55)
Optical trapping with high forces reveals unexpected behaviors of prion fibrils (54)
Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study. (54)
Prion-like proteins sequester and suppress the toxicity of huntingtin exon 1 (54)
Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome (53)
Molecular population genetics and evolution of a prion-like protein in Saccharomyces cerevisiae. (53)
Coordinate regulation of beta-lactamase induction and peptidoglycan composition by the amp operon. (52)
Developmentally regulated nuclear transport of transcription factors in Drosophila embryos enable the heat shock response. (52)
Loss of native &agr;-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells (51)
Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes (51)
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs (50)
The role of Hsp104 in stress tolerance and [PSI+] propagation in Saccharomyces cerevisiae. (50)
Transcriptional derepression of the Saccharomyces cerevisiae HSP26 gene during heat shock. (48)
Conversion of a yeast prion protein to an infectious form in bacteria (48)
Mitochondrial metabolism promotes adaptation to proteotoxic stress (48)
The Peptidyl-prolyl Isomerase Domain of the CyP-40 Cyclophilin Homolog Cpr7 Is Not Required to Support Growth or Glucocorticoid Receptor Activity in Saccharomyces cerevisiae* (48)
AmpG, a signal transducer in chromosomal beta-lactamase induction. (46)
Combining DNP NMR with segmental and specific labeling to study a yeast prion protein strain that is not parallel in-register (46)
Prion Pathogenesis is Independent of Caspase-12 (45)
Sequences of wild-type and mutant ampD genes of Citrobacter freundii and Enterobacter cloacae (45)
An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component (44)
Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor Biosynthesis (42)
Rnq 1 : An Epigenetic Modifier of Protein (41)
Combating neurodegenerative disease with chemical probes and model systems. (41)
Investigating protein conformation-based inheritance and disease in yeast. (40)
Genetic basis of induction and overproduction of chromosomal class I beta-lactamase in nonfastidious gram-negative bacilli. (39)
Heritable yeast prions have a highly organized three-dimensional architecture with interfiber structures (39)
Rapid Selection of Cyclic Peptides that Reduce Alpha- Synuclein Toxicity in Yeast and Animal Models (39)
Sequence-dependent denaturation energetics: A major determinant in amyloid disease diversity (38)
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus (38)
Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity (37)
Alternative assembly pathways of the amyloidogenic yeast prion determinant Sup35–NM (37)
A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance (36)
Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers (36)
Self-perpetuating epigenetic pili switches in bacteria (36)
BETASCAN: Probable beta-amyloids Identified by Pairwise Probabilistic Analysis (36)
Hsp90 and Chromatin: Where is the Link? (35)
An inter‐species protein–protein interaction network across vast evolutionary distance (34)
Profoundly different prion diseases in knock-in mice carrying single PrP codon substitutions associated with human diseases (34)
Probing the Role of PrP Repeats in Conformational Conversion and Amyloid Assembly of Chimeric Yeast Prions* (32)
Context dependent neuroprotective properties of prion protein (PrP) (32)
Diminishing Apoptosis by Deletion of Bax or Overexpression of Bcl-2 Does Not Protect against Infectious Prion Toxicity In Vivo (32)
Interleukin-1 beta increases the biosynthesis of the heat shock protein hsp70 and selectively decreases the biosynthesis of five proteins in rat pancreatic islets. (31)
16 Posttranscriptional Regulation of Heat Shock Protein Synthesis in Drosophila (31)
A chaperone pathway in protein disaggregation: Hsp26 ALTERS THE NATURE OF PROTEIN AGGREGATES TO FACILITATE REACTIVATION BY Hsp104. VOLUME 280 (2005) PAGES 23869-23875 (31)
Evidence that alpha-synuclein does not inhibit phospholipase D. (30)
Navigating the ClpB channel to solution (30)
The basis for a heat-induced developmental defect: defining crucial lesions. (30)
HSF1 phase transition mediates stress adaptation and cell fate decisions (29)
From yeast to patient neurons and back again: Powerful new discovery platforms (29)
Chromosomal beta-lactam resistance in enterobacteria. (29)
Subcellular differentiation in sporulating yeast cells (28)
Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors. (27)
A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance. (24)
Phenotypic screens for compounds that target the cellular pathologies underlying Parkinson's disease. (24)
Heat shock--a comparison of Drosophila and yeast. (23)
Interactions among α-synuclein, dopamine, and biomembranes (22)
[PSI+], SUP35, and chaperones. (21)
Expression of a Drosophila heat shock protein in mammalian cells: transient association with nucleoli after heat shock. (21)
APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia (21)
FKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteome (21)
A possible epigenetic mechanism for the persistence of memory. (21)
Overcoming fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles. (20)
Purification and properties of Hsp104 from yeast. (20)
Hsp90 and chromatin (20)
STITCHER: Dynamic assembly of likely amyloid and prion β-structures from secondary structure predictions (20)
Physical properties of polymorphic yeast prion amyloid fibers. (20)
The Schizosaccharomyces pombe Hsp104 Disaggregase Is Unable to Propagate the [PSI +] Prion (20)
Contribution of N‐ and C‐terminal domains to the function of Hsp90 in Saccharomyces cerevisiae (19)
Signalling proteins in enterobacterial AmpC beta-lactamase regulation. (19)
Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation (19)
4 – Coordinate and Noncoordinate Gene Expression during Heat Shock: A Model for Regulation (19)
Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy (19)
Detection of compounds that rescue Rab1-synuclein toxicity. (18)
The yeast prion [PSI+]: molecular insights and functional consequences. (18)
RNA-directed DNA methylation in Arabidopsis (18)
Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates. (17)
Hypusine formation in eukaryotic initiation factor 4D is not reversed when rates or specificity of protein synthesis is altered. (17)
Aggregation and Fibril Structure of AβM01-42 and Aβ1-42. (17)
Chapter 23 Mechanisms of chromosomal β-lactamase induction in Gram-negative bacteria (16)
Hsp90 as a capacitor of phenotypic (15)
ML212: A small-molecule probe for investigating fluconazole resistance mechanisms in Candida albicans (15)
Induction and maintenance of nonsymmetrical DNA methylation in Neurospora (15)
Induction of chromosomal β-lactamase expression in enterobacteria (14)
Heat shock protein 100 and the amastigote stage-specific A2 proteins of Leishmania donovani (14)
PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4. (14)
This contribution is part of the special series of Inaugural Articles by members of the National Academy of Sciences elected on April 29 , 1997 . In vivo functions of the Saccharomyces cerevisiae Hsp 90 chaperone (14)
Context-dependent perturbation of neural systems in transgenic mice expressing a cytosolic prion protein (14)
Orientation of aromatic residues in amyloid cores: Structural insights into prion fiber diversity (13)
Pioneer cells established by the [SWI+] prion can promote dispersal and out-crossing in yeast (13)
Scarless Gene Tagging with One-Step Transformation and Two-Step Selection in Saccharomyces cerevisiae and Schizosaccharomyces pombe (13)
Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism. (13)
Interactions among prions and prion “strains” in yeast (13)
Hsp101 plays a crucial role in thermotolerance in Arabidopsis. (13)
Translational Regulation in the Heat-Shock Response of Drosophila Cells (12)
A nucleolar protein allows viability in the absence of the essential ER-residing molecular chaperone calnexin (11)
Histone H3 lysine 4 methylation is mediated by Set1 and promotes maintenance of active chromatin states in fission yeast (11)
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis. (11)
Splice isoform and pharmacological studies reveal that sterol depletion relocalizes α-synuclein and enhances its toxicity (10)
TorsinA and the TorsinA-Interacting Protein Printor Have No Impact on Endoplasmic Reticulum Stress or Protein Trafficking in Yeast (10)
Self-perpetuating structural states in biology, disease, and genetics (10)
Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast. (10)
Mad cows meet mad yeast: the prion hypothesis. (10)
Curing Chaperones Hsp 104 and Hsp 70 in Prion Antagonistic Interactions between Yeast (9)
mouse models of Huntington ' s and prion diseases The power of automated high-resolution behavior analysis revealed by its application to (8)
De novo generation of a PrP Sc -like (8)
Loss of Hsp 70 Exacerbates Pathogenesis but not Levels of Fibrillar Aggregates in a Mouse Model of Huntington ’ s Disease (8)
Heat-Shock Protein hsp90 Governs the Activity of pp60 (8)
Illuminating aggregate heterogeneity in neurodegenerative disease (7)
Yeast can accommodate phosphotyrosine: v-Src toxicity in yeast arises from a single disrupted pathway (7)
Self-perpetuating changes in Sup35 protein conformation as a mechanism of heredity in yeast. (7)
Santagata Supports the Anabolic Malignant State Tight Coordination of Protein Translation and HSF 1 Activation (7)
Differential mRNA Stability: A Regulatory Strategy for Hsp70 Synthesis (6)
Prion proteins: one surprise after another. (6)
THE ROLE OF HSP104 IN STRESS TOLERANCE AND PRION MAINTENANCE (6)
Conservation of a portion of the S. cerevisiae Ure2p prion domain that interacts with the full-length protein (6)
. . . but yeast prion offers clues about evolution (6)
Heritable chromatin structure: Mapping “memory” in histones H3 and H4 (6)
Bridging the gap between high-throughput genetic and transcriptional data reveals cellular pathways responding to alpha-synuclein toxicity (5)
The Cytoplasmic Prolyl-tRNA Synthetase of the Malaria Parasite is a Dual-Stage Target for Drug Development (5)
Response from Chernoff et al. (5)
Evidence That #-Synuclein Does Not Inhibit Phospholipase D † (4)
A Phenotype Under Challenge (4)
Prion Switching in Response to Environmental (4)
Nicolas Rohner for Loss of Eyes in Cavefish Cryptic Variation in Morphological Evolution : HSP 90 as a Capacitor (4)
Identification of Small Molecules that Selectively Inhibit Fluconazole-Resistant Candida Albicans in the Presence of Fluconazole but not in its Absence - Probe 3 (4)
Induction of chromosomal beta-lactamase expression in enterobacteria. (4)
Green tea ( 2 )-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington ’ s disease models (3)
Using yeast to understand protein folding diseases: an interview with Susan Lindquist by Kristin Kain. (3)
Prion formation by a yeast (3)
Cdc 37 is a molecular chaperone with specific functions in signal transductlon (3)
Yeast Cells as a Discovery Platform for Parkinson's Disease and other Protein Misfolding Diseases (3)
Stress-induced proteins : proceedings of a Hoffmann-La Roche-director's sponsors UCLA symposia, held at Keystone, Colorado, April 10-16, 1988 (3)
Genetic Analysis of Heat Shock Protein Functions in Yeast (3)
Corrigendum: Combating neurodegenerative disease with chemical probes and model systems (3)
Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress (2)
Interview: Protein folding and studies of neurodegenerative diseases. (2)
Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. (2)
Cooper in Parkinson ' s Models-Synuclein Blocks ER-Golgi Traffic and Rab 1 Rescues Neuron Loss (2)
Profoundly different prion diseases in knockin mice carrying single PrP codon substitutions associated with human diseases Citation (2)
Won't you change partners and dance? (2)
$^{13}C$ NMR Studies of Metabolic Pathways Regulated by HSP104 in Saccharomyces cerevisiae (2)
Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity (2)
A cytoplasmically inherited prionlike genetic element in yeast. (1)
Three Quite Different Things That Matter to Me (1)
White How Detection of Compounds That Rescue Rab 1-Synuclein Toxicity (1)
Abstract P6-15-06: Heat Shock Protein 90 Inhibition Limits the Emergence of Tamoxifen Resistance (1)
Author-Initiated Retraction: Donmez et al., SIRT1 Protects against α-Synuclein Aggregation by Activating Molecular Chaperones (1)
Susan Lee Lindquist (1949–2016) (1)
Disrupting fluconazole resistance in Candida albicans clinical isolates with tetracyclic indoles (1)
Author response: Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome (1)
and Prognosis Progress − Ameliorate Protein Misfolding and Aggregation Diseases Chemical and Biological Approaches for Adapting Proteostasis to service (1)
Erratum: Transgenerational epigenetic inheritance: how important is it? (1)
Inactivating Heat Shock Factor 1 (HSF1) in Acute Myeloid Leukemia By Pharmacological Inhibition of eIF4a: A Promising Therapeutic Approach (1)
Transcriptional derepression of the Saccharomyces cerevisiae HSP26 gene during heat shock (1)
Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition. (1)
Table 3, Physical Properties of 4-chlorobenzamide Derivatives (0)
WP: Workshop Lectures (0)
Preferential deadenylation of Hsp70 mRNA plays a key role in regulating Hsp70 expression in Drosophila melanogaster (0)
Compounds, compositions and method for inhibiting the toxicity of a-synuclein. (0)
Does heterochromatin protein 1 always follow code (0)
Yeast Cells as a Discovery Platform for Neurodegenerative Disease (0)
Figure 5, ML316 Selectively Inhibits Growth of C. albicans (A and B) over 3T3 Fibroblasts (C) (0)
Modelling neurodegeneration in S . cerevisiae : Why cook with Baker ’ s yeast ? (0)
Figure 62, Spectroscopic data for SID 99376533 (0)
Aggregation of Trp>Glu Mutants of the Human Gamma-D Crystallin: A Model for Hereditary or UV-Induced Cataract (0)
Figure 41, Spectroscopic data for SID 99376498 (0)
Observation of Amyloid-Like Fibers of the Sup35 Protein from Saccharomyces Cerevisiae (0)
Table 10, Heteroaromatic Substitution of the 7-chloroquinoline (0)
Table 2, Summary of Probe Properties Computed from Structure ML316 (0)
Heat shock proteins affect RNA processing during the heat shock response of Saccharomyces cerevisiae (0)
Table 1, Plasma Stability of Probe ML316 and analogs CID3889161 and CID56604835 (0)
Inhibition of mitochondrial ferredoxin 1 (FDX1) prevents adaptation to proteotoxic stress (0)
hsp26 of Saccharomyces cerevisiae is related to the superfamily of small heat shock proteins but is without a demonstrable function (0)
New Mechanisms of Inheritance Based on Self-perpetuating Changes in Protein Conformation (0)
Excited About Science (0)
[Figure], 1H NMR Spectrum (300 MHz, CDCl3) of Analog CID 17581348 (Entry 12, Table 2) (0)
Figure 15, Spectroscopic data for SID 99245531 (0)
P5-01-13: High Levels of Nuclear Heat Shock Factor 1 (HSF1) Are Associated with Poor Prognosis in Breast Cancer: Results from the Nurses' Health Study. (0)
Figure 60, Spectroscopic data for SID 99245570 (0)
Abstract OT3-2-05: Randomized phase II study of fulvestrant with or without ganetespib in patients (pts) with hormone receptor (HR)-positive metastatic breast cancer (0)
Figure 57, Spectroscopic data for SID 99376553 (0)
P3-01-09: Oncogenic Activation of HSF1 Enables the Malignant Progression of Breast Carcinoma. (0)
Figure 55, Spectroscopic data for SID 99376554 (0)
Figure 38, Spectroscopic data for SID 99376525 (0)
Studies of the aggregation of mutant proteins in vitro provide insights into the genetics of amyloid diseases (0)
Figure 26, Spectroscopic data for SID 99376527 (0)
Yeun Chung Derived Neurons − Patient-Synuclein Toxicity in Parkinson α Identification and Rescue (0)
Figure 4, Probe Stability in PBS solution at 23 °C (0)
Self-Perpetuating Changes in Sup35 Protein Conformation as A mechanism of Heredity in Yeast (0)
Chaperoning brain degeneration (0)
Figure 17, Spectroscopic data for SID 99376521 (0)
Accelerating Yeast Prion Biology using Droplet Microfluidics (0)
Heat-shock protein 104 expression is sufficient for thermotolerance in yeast ( chaperones / stress tolerance / heat-shock factor / prion ) (0)
Mad cows and psi-chotic yeast: an extension of the prion hypothesis (0)
Table 1, Evaluation of 16 Synthetic Ester and Amide Analogs (0)
[Figure], UPLC-MS of Analog CID 49835881 (0)
hsp82 is an essential protein that is required in higher concentrations for growth of cells at higher temperatures (0)
Figure 56, Spectroscopic data for SID 99376537 (0)
Figure 25, Spectroscopic data for SID 99376504 (0)
Figure 13, Best-in-class Chemosensitizers for Reversing Fluconazole Resistance (MIC=1.2–2.8 μM) (0)
Physical Properties of Yeast Prion Proteins Studied with Optical Tweezers (0)
Probing Structure and Mechanics of Yeast Prion Proteins with Optical Tweezers (0)
Table 9, Physical Properties of Substituted Quinoline Analogs (0)
Table 7, Physical Properties of Piperazine Derivatives (0)
Figure 36, Spectroscopic data for SID 99245548 (0)
[Figure], 1H NMR Spectrum (300 MHz, CDCl3) of Analog CID 49868637 (Entry 3, Table 2) (0)
Prions, From Structure to Epigenetics and Neuronal Functions (0)
[Figure], UPLC-MS Chromatogram of Analog CID 17581348 (0)
[Figure], UPLC-MS Chromatogram of Analog CID 49868635 (0)
Methods for building genomic networks and uses thereof (0)
Figure 46, Spectroscopic data for SID 99376513 (0)
Scheme 1, Synthesis of the Probe (ML212) (0)
In Situ Peroxidase Labelin g and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons Graphical (0)
[Figure], 1H NMR Spectra (300 MHz, CDCl3) of Analog CID 20877381 (Table 8, entry 7) (0)
[Figure], UPLC-MS of Analog CID 13330955 (0)
Expanding the prion model for the yeast [PSI+] element: Response (0)
HeatShockProteins Affect RNA Processing during theHeatShock Response ofSaccharomyces cerevisiae (0)
[Figure], UPLC-MS of Analog CID 46856255 (0)
Figure 16, Spectroscopic data for SID 99376520 (0)
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington's disease by using an automated filter retardation assay (0)
Abstract A23: Cell autonomous and nonautonomous activities of heat shock factor 1 support tumor initiation, progression, and metastasis (0)
Alzheimer ' s Disease Risk Factors in Yeast Toxicity , Endocytic Trafficking , and β Functional Links Between A (0)
Transient Hsp90 suppression promotes a heritable change in protein translation (0)
Figure 34, Spectroscopic data for SID 99245539 (0)
Metal nanowires from self-assembled protein fibers (0)
Figure 21, Spectroscopic data for SID 99376507 (0)
Protein folding shapes the adaptive value of genetic variation (0)
Figure 24, Spectroscopic data for SID 99376500 (0)
Figure 50, Spectroscopic data for SID 99376557 (0)
Figure 10, Evaluating Loss of C. glabrata Mitochondrial Membrane Potential with JC-1 (0)
Environmentally Acquired Traits Epigenetics in the Extreme: Prions and the Inheritance of (0)
The Stress Response and Stress Proteins (0)
Figure 33, Spectroscopic data for SID 99245557 (0)
[Figure], UPLC-MS Chromatogram of Analog CID 49843308 (0)
Table 4, Evaluation of Additional Amides and Amide Bond Surrogates (0)
Transmission of prions (0)
Figure 32, Spectroscopic data for SID 99376523 (0)
Susan L. Lindquist. (0)
Figure 20, Spectroscopic data for SID 99376501 (0)
Table 5, Physical Properties of Additional Amides and Amide Bond Surrogates (0)
Figure 35, Spectroscopic data for SID 99245543 (0)
Analysis of the AAA sensor-2 ATPase domain of Hsp104 wi fluorescent probe of nucleoti (0)
Figure 47, Spectroscopic data for SID 99376519 (0)
PARTICIPATION OF STRESS PROTEINS IN EXOGENOUS LUCIFERASE EXPRESSION IN YEAST (0)
Aggregation Diseases ndProteostasis to Ameliorate Protein Misfolding a Chemical and Biological Approaches for Adapting (0)
Figure 59, Spectroscopic data for SID 99376552 (0)
Arthur M. Sackler, M.D. (0)
[Figure], UPLC-MS Chromatogram of Analog CID 1508304 (0)
[Figure], UPLC-MS of Analog CID 20877557 (0)
Figure 49, Spectroscopic data for SID 99376538 (0)
[Figure], 1H NMR Spectrum (300 MHz, CDCl3) of Analog CID 49766513 (Entry 6, Table 1) (0)
Figure 53, Spectroscopic data for SID 99376524 (0)
Table 1, Summary of Assays Completed (0)
Figure 10, Critical Path (0)
Tight Coordination of Protein Translation and Heat Shock Factor 1 Activation Supports the Anabolic Malignant State (0)
Mad Cows Meet Psi-chotic Yeast : Minireview The Expansion of the Prion Hypothesis (0)
Probing Metabolic Requirements for Fungal Virulence — Probe 1 (0)
Abstract PR07: Mechanisms of stromal reprogramming mediated by heat shock factor 1 (0)
Figure 19, Spectroscopic data for SID 99376499 (0)
Abstracts of papers presented at the 1994 Meeting on Biology of Heat Shock Proteins & Molecular Chaperones, May 4-May 8, 1994 (0)
Figure 37, Spectroscopic data for SID 99376512 (0)
Preferential Deadenylation ofHsp7OmRNA Plays a KeyRole inRegulating Hsp7OExpression inDrosophila melanogaster (0)
Figure 27, Spectroscopic data for SID 99245535 (0)
Figure 23, Spectroscopic data for SID 99376531 (0)
Figure 29, Spectroscopic data for SID 99376510 (0)
Chung Derived Neurons − Patient-Synuclein Toxicity in Parkinson α Identification and Rescue of (0)
Figure 51, Spectroscopic data for SID 99245561 (0)
Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition. (0)
[Figure], 1H NMR Spectra (300 MHz, CDCl3) of Analog CID 20877557 (Table 3, entry 11) (0)
Figure 1, Some known inhibitors of fungal mitochondria oxidative phosphorylation (0)
Figure 39, Spectroscopic data for SID 99376508 (0)
Figure 30, Spectroscopic data for SID 99376511 (0)
Over the years , yeast , fruit fl ies , mustard plants and mice have struggled through their own versions of an extreme reality TV show in the laboratory of Whitehead Member (0)
buffering role of HSP 90 in disease manifestations d HSP 90 chaperoning shapes allele expressivity (0)
[Figure], 1H NMR Spectra (300 MHz, CDCl3) of Analog CID 13330955 (Table 3, entry 7) (0)
A method for detecting in yeast for influence by means of protein folding (0)
[Figure], UPLC-MS Chromatogram of Analog CID 49843090 (0)
Lindquist Protein Folding Sculpting Evolutionary Change (0)
Figure 42, Spectroscopic data for SID 99376530 (0)
Table 3, SAR Analysis of Ethyl Carbamate (0)
A flurry of folding problems: an interview with Susan Lindquist by Jane Gitschier. (0)
Mammalian-Membrane-Two-Hybrid ( MaMTH ) : a novel split-ubiquitin assay for investigation of signaling pathways in human cells (0)
Figure 45, Spectroscopic data for SID 99245559 (0)
Peptide microarray-based mapping of prion transmission barriers (0)
Figure 43, Spectroscopic data for SID 99376518 (0)
Abstract A28: Targeting the epigenetic state regulating cancer cell vulnerability to proteasome inhibition (0)
Abstract C132: Targeting heat shock factor 1 improves the antitumor efficiency of hyperthermia. (0)
Figure 52, Spectroscopic data for SID 99245569 (0)
Figure 22, Spectroscopic data for SID 99245567 (0)
Binding oftheCitrobacter freundii AmpRRegulator toaSingle DNA Site Provides BothAutoregulation andActivation ofthe Inducible ampCr-Lactamase Gene (0)
Sequences ofWild-Type andMutantampDGenesof Citrobacterfreundii andEnterobacter cloacae (0)
Unraveling Molecular Mechanisms and Structures of Self-Perpetuating Prions (0)
Table 2, Summary of SAR Performed Upon the 4-chlorobenzamide (0)
Table 6, Biological Assay of Piperazine Derivatives (0)
Table 8, Summary of SAR Performed with Substituted Quinolines (0)
[Figure], 1H NMR Spectra (300 MHz, CDCl3) of Analog CID 46856252 (Table 8, entry 3) (0)
Figure 18, Spectroscopic data for SID 99376522 (0)
National Academy of Sciences Sackler Colloquia Series (0)
Fungal Prions and Evolutionary Trajectories (0)
Inhibition of translation initiation factor eIF4a inactivates heat shock factor 1 (HSF1) and exerts anti-leukemia activity in AML (0)
[Figure], 13C NMR Spectrum (125 MHz, CDCl3) of the Probe (CID7694069/ML229) (0)
Figure 58, Spectroscopic data for SID 99376545 (0)
Figure 48, Spectroscopic data for SID 99376502 (0)
Naturally occurring fibrillar proteins can induce AA amyloidosis by a prion-like mechanism (0)
The insulation of genes from external enhancers and silencing chromatin (0)
Simple Cellular Solutions to Complex Problems (0)
Table 11, Physical Properties of the Heteroaromatic Surrogates (0)
[Figure], UPLC-MS of Analog CID 20877322 (0)
Abstracts of papers presented at the 1998 Meeting on Molecular Chaperones and the Heat Shock Response, May 6-May 10, 1998 (0)
Figure 28, Spectroscopic data for SID 99376509 (0)
HSP26 Gene during Heat Shock (0)
yeast prion A heritable switch in carbon source utilization driven by an unusual (0)
Figure 54, Spectroscopic data for SID 99376503 (0)
Figure 31, Spectroscopic data for SID 99245553 (0)
Method of proof in yeast for medium affect the protein folding (0)
Prion Proteins: Surprising Genetics, Surprising Biology and Surprising Folds (0)
Figure 44, Spectroscopic data for SID 99376526 (0)
Figure 40, Spectroscopic data for SID 99376517 (0)
Figure 61, Spectroscopic data for SID 99376515 (0)
13 Stress Tolerance, Metabolism, and Development: The Many Flavors of Trehalose (0)
Figure 14, Spectroscopic data for SID 99245537 (0)

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