Tatsutoshi Nakahata
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Japanese teacher
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Communications
Tatsutoshi Nakahata's Degrees
- Bachelors Japanese Language and Literature University of Tokyo
- Masters Teaching Japanese as a Foreign Language Kyoto University
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(Suggest an Edit or Addition)Tatsutoshi Nakahata's Published Works
Published Works
- Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. (2009) (2041)
- NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells. (2002) (1312)
- Generation of Pluripotent Stem Cells from Neonatal Mouse Testis (2004) (810)
- Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. (1996) (669)
- Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. (2013) (661)
- Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. (2002) (619)
- Frequent inactivation of A20 in B-cell lymphomas (2009) (559)
- Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease. (1989) (519)
- Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocyte-macrophages in humans. (2001) (506)
- Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells (2012) (504)
- Early-onset sarcoidosis and CARD15 mutations with constitutive nuclear factor-kappaB activation: common genetic etiology with Blau syndrome. (2004) (473)
- Unique multipotent cells in adult human mesenchymal cell populations (2010) (420)
- Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease (1989) (402)
- Selective growth of human mast cells induced by Steel factor, IL-6, and prostaglandin E2 from cord blood mononuclear cells. (1996) (333)
- Identification in culture of a class of hemopoietic colony-forming units with extensive capability to self-renew and generate multipotential hemopoietic colonies. (1982) (321)
- Hemopoietic colony-forming cells in umbilical cord blood with extensive capability to generate mono- and multipotential hemopoietic progenitors. (1982) (311)
- In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets. (1990) (290)
- Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor. (2000) (287)
- Suppression of STAT5 Functions in Liver, Mammary Glands, and T Cells in Cytokine-Inducible SH2-Containing Protein 1 Transgenic Mice (1999) (280)
- Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model. (2003) (254)
- Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts (2011) (253)
- High incidence of NLRP3 somatic mosaicism in patients with chronic infantile neurologic, cutaneous, articular syndrome: results of an International Multicenter Collaborative Study. (2011) (253)
- NOD / SCID / cnull mouse : an excellent recipient mouse model for engraftment of human cells (2002) (248)
- Characterization of side-population cells in human normal endometrium. (2007) (227)
- Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality. (2002) (201)
- Retrospective nationwide survey of Japanese patients with transfusion‐dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality (2007) (200)
- Generation of definitive hematopoietic stem cells from murine early yolk sac and paraaortic splanchnopleures by aorta-gonad-mesonephros region-derived stromal cells. (2001) (191)
- Induction of the high-affinity IgE receptor (FcɛRI) on human mast cells by IL-4 (1996) (188)
- Leptin stimulates the proliferation of murine myelocytic and primitive hematopoietic progenitor cells. (1997) (184)
- A stochastic model of self‐renewal and commitment to differentiation of the primitive hemopoietic stem cells in culture (1982) (183)
- Effects of T-helper 2-type cytokines, interleukin-3 (IL-3), IL-4, IL-5, and IL-6 on the survival of cultured human mast cells. (1995) (183)
- Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines. (1998) (181)
- Hepatic differentiation induced by oncostatin M attenuates fetal liver hematopoiesis. (1999) (181)
- Renewal and commitment to differentiation of hemopoietic stem cells (an interpretive review) (1983) (178)
- The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. (2009) (175)
- Generation of functional erythrocytes from human embryonic stem cell-derived definitive hematopoiesis (2008) (175)
- Human mast cells produce IL-13 by high-affinity IgE receptor cross-linking: enhanced IL-13 production by IL-4-primed human mast cells. (1998) (171)
- Synergism of BSF-2/interleukin 6 and interleukin 3 on development of multipotential hemopoietic progenitors in serum-free culture (1988) (166)
- Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein (2000) (162)
- Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease (2011) (161)
- Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells (2010) (157)
- Changes in cell surface antigen expressions during proliferation and differentiation of human erythroid progenitors. (1992) (155)
- Role of the NOD2 genotype in the clinical phenotype of Blau syndrome and early-onset sarcoidosis. (2009) (150)
- Interleukin-4 promotes the development of tryptase and chymase double-positive human mast cells accompanied by cell maturation. (1998) (146)
- In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aorta-gonad-mesonephros region. (1998) (146)
- A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors. (2005) (143)
- The role of mel-18, a mammalian Polycomb group gene, during IL-7-dependent proliferation of lymphocyte precursors. (1997) (140)
- Acetylation of GATA-4 Is Involved in the Differentiation of Embryonic Stem Cells into Cardiac Myocytes* (2002) (139)
- Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice. (2003) (138)
- Interleukin-6 supports human megakaryocytic proliferation and differentiation in vitro. (1991) (135)
- Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT21 (2009) (134)
- Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes. (1999) (133)
- Somatic mosaicism of CIAS1 in a patient with chronic infantile neurologic, cutaneous, articular syndrome. (2005) (132)
- Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients. (2008) (122)
- CD34 expression on long-term repopulating hematopoietic stem cells changes during developmental stages. (2001) (122)
- NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models. (2008) (122)
- Neonatal diabetes mellitus and neonatal polycystic, dysplastic kidneys: Phenotypically discordant recurrence of a mutation in the hepatocyte nuclear factor-1beta gene due to germline mosaicism. (2004) (122)
- Side population cells contribute to the genesis of human endometrium. (2008) (120)
- Bone marrow‐derived cells expressing Iba1 are constitutively present as resident tissue macrophages in the mouse cochlea (2008) (120)
- Evidence for the presence of murine primitive megakaryocytopoiesis in the early yolk sac. (2001) (120)
- Analysis of interleukin 6 receptor and gp130 expressions and proliferative capability of human CD34+ cells (1996) (119)
- Characterization of mast cell-committed progenitors present in human umbilical cord blood. (1999) (119)
- Clonal origin of murine hemopoietic colonies with apparent restriction to granuclocyte‐macrophage‐megakaryocyte (GMM) differentiation (1982) (119)
- Ex vivo expansion of hematopoietic stem cells by cytokines. (2002) (114)
- Derivation of Mesenchymal Stromal Cells from Pluripotent Stem Cells through a Neural Crest Lineage using Small Molecule Compounds with Defined Media (2014) (114)
- Preferential Selection of Human T-Cell Leukemia Virus Type 1 Provirus Lacking the 5′ Long Terminal Repeat during Oncogenesis (2007) (114)
- Renewal and commitment to differentiation of hemopoietic stem cells (an interpretive review). (1983) (114)
- Outcome of risk-based therapy for infant acute lymphoblastic leukemia with or without an MLL gene rearrangement, with emphasis on late effects: a final report of two consecutive studies, MLL96 and MLL98, of the Japan Infant Leukemia Study Group (2007) (113)
- Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells under Serum- and Feeder Cell-Free Conditions (2013) (112)
- Craniotabes in normal newborns: the earliest sign of subclinical vitamin D deficiency. (2008) (109)
- A Novel Serum-Free Monolayer Culture for Orderly Hematopoietic Differentiation of Human Pluripotent Cells via Mesodermal Progenitors (2011) (108)
- Human Umbilical Cord-Derived Mesenchymal Stromal Cells Differentiate Into Functional Schwann Cells That Sustain Peripheral Nerve Regeneration (2010) (107)
- The C42R mutation in the Kir6.2 (KCNJ11) gene as a cause of transient neonatal diabetes, childhood diabetes, or later-onset, apparently type 2 diabetes mellitus. (2005) (107)
- Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells. (2007) (106)
- A novel mechanism for imatinib mesylate-induced cell death of BCR-ABL-positive human leukemic cells: caspase-independent, necrosis-like programmed cell death mediated by serine protease activity. (2004) (105)
- Prospective multicenter trial comparing repeated immunosuppressive therapy with stem-cell transplantation from an alternative donor as second-line treatment for children with severe and very severe aplastic anemia. (2008) (103)
- Allogeneic hematopoietic stem cell transplantation for 27 children with juvenile myelomonocytic leukemia diagnosed based on the criteria of the International JMML Working Group (2002) (100)
- Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties. (2007) (98)
- Natural killer cell depletion by anti-asialo GM1 antiserum treatment enhances human hematopoietic stem cell engraftment in NOD/Shi-scid mice (2000) (98)
- Obesity and the prevalence of allergic diseases in schoolchildren (2008) (94)
- Erythropoietin-independent erythrocyte production: signals through gp130 and c-kit dramatically promote erythropoiesis from human CD34+ cells (1996) (92)
- X-linked ectodermal dysplasia and immunodeficiency caused by reversion mosaicism of NEMO reveals a critical role for NEMO in human T-cell development and/or survival. (2004) (91)
- Identification of a High‐Frequency Somatic NLRC4 Mutation as a Cause of Autoinflammation by Pluripotent Cell–Based Phenotype Dissection (2017) (90)
- Highly Efficient Ex Vivo Expansion of Human Hematopoietic Stem Cells Using Delta1‐Fc Chimeric Protein (2006) (90)
- Modeling the Early Phenotype at the Neuromuscular Junction of Spinal Muscular Atrophy Using Patient-Derived iPSCs (2015) (89)
- SPINK5 polymorphism is associated with disease severity and food allergy in children with atopic dermatitis. (2005) (89)
- Suspension culture of human mast cells/basophils from umbilical cord blood mononuclear cells. (1983) (88)
- Clonal assay of mouse mast cell colonies in methylcellulose culture. (1982) (88)
- Erythroid progenitors differentiate and mature in response to endogenous erythropoietin. (2000) (88)
- Expression of p21Cip1/Waf1/Sdi1 and p27Kip1Cyclin-Dependent Kinase Inhibitors During Human Hematopoiesis (1999) (86)
- Early pathogenesis of Duchenne muscular dystrophy modelled in patient-derived human induced pluripotent stem cells (2015) (86)
- Extensive proliferation of mature connective-tissue type mast cells in vitro (1986) (86)
- Generation of transplantable, functional satellite‐like cells from mouse embryonic stem cells (2009) (85)
- Characterization of cord-blood-derived human mast cells cultured in the presence of Steel factor and interleukin-6. (1995) (85)
- The IVS4 + 4 A to T mutation of the fanconi anemia gene FANCC is not associated with a severe phenotype in Japanese patients. (2000) (80)
- Chemotactic and chemokinetic activities of stem cell factor on murine hematopoietic progenitor cells. (1996) (80)
- Myelodysplastic syndrome in childhood: a retrospective study of 189 patients in Japan (2001) (78)
- Cell surface antigen expression in human erythroid progenitors: erythroid and megakaryocytic markers. (1994) (78)
- Clonal Assay of Mouse Mast Cell Colonies in Methylcellulose Culture (1982) (78)
- TH2 dominance and defective development of a CD8+ dendritic cell subset in Id2-deficient mice. (2003) (77)
- Effects of interleukin-3 and interleukin-4 on the development of "connective tissue-type" mast cells: interleukin-3 supports their survival and interleukin-4 triggers and supports their proliferation synergistically with interleukin-3 (1990) (77)
- Selective Development of Myogenic Mesenchymal Cells from Human Embryonic and Induced Pluripotent Stem Cells (2012) (76)
- Interleukin-4 induces homotypic aggregation of human mast cells by promoting LFA-1/ICAM-1 adhesion molecules. (1997) (76)
- Defective response to thrombopoietin and impaired expression of c‐mpl mRNA of bone marrow cells in congenital amegakaryocytic thrombocytopenia (1997) (75)
- Parental origin of normal X chromosomes in Turner syndrome patients with various karyotypes: implications for the mechanism leading to generation of a 45,X karyotype. (2002) (75)
- Peroxisome proliferator‐activated receptors are expressed in human cultured mast cells: a possible role of these receptors in negative regulation of mast cell activation (2000) (74)
- Dominant‐negative STAT1 SH2 domain mutations in unrelated patients with mendelian susceptibility to mycobacterial disease (2012) (71)
- Prospective characterization of neural stem cells by flow cytometry analysis using a combination of surface markers (2005) (71)
- Inhibitory Effect of Adenosine on Degranulation of Human Cultured Mast Cells upon Cross-linking of FcϵRI (1998) (70)
- Induction of autophagy in malignant rhabdoid tumor cells by the histone deacetylase inhibitor FK228 through AIF translocation (2009) (70)
- Cloning and expression of human B cell-specific transcription factor BACH2 mapped to chromosome 6q15 (2000) (70)
- Abnormal neutrophil maturation in a neutrophil defect with morphologic abnormality and impaired function. (1979) (69)
- FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells (2003) (68)
- A method to identify cDNAs based on localization of green fluorescent protein fusion products. (2000) (67)
- Synergistic action of Flt3 and gp130 signalings in human hematopoiesis. (1997) (66)
- Expression of p21(Cip1/Waf1/Sdi1) and p27(Kip1) cyclin-dependent kinase inhibitors during human hematopoiesis. (1999) (64)
- Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. (2012) (64)
- Selective infection of CD4+ effector memory T lymphocytes leads to preferential depletion of memory T lymphocytes in R5 HIV-1-infected humanized NOD/SCID/IL-2Rgammanull mice. (2009) (64)
- A combination of stem cell factor and granulocyte colony‐stimulating factor enhances the growth of human progenitor B cells supported by murine stromal cell line MS‐5 (1998) (64)
- Age‐related changes in thrombopoietin in children: reference interval for serum thrombopoietin levels (1999) (64)
- IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells. (2006) (62)
- Development of primitive and definitive hematopoiesis from nonhuman primate embryonic stem cells in vitro (2004) (61)
- AKR‐501 (YM477) a novel orally‐active thrombopoietin receptor agonist (2009) (61)
- Stem cell factor enhances proliferation, but not maturation, of murine megakaryocytic progenitors in serum-free culture. (1992) (61)
- Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body. (2004) (60)
- Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. (2010) (60)
- The common marmoset as a target preclinical primate model for cytokine and gene therapy studies. (1999) (59)
- Elevation of Serum Thrombopoietin Precedes Thrombocytosis in Kawasaki Disease (1998) (58)
- Hematopoietic Capability of CD34+ Cord Blood Cells: A Comparison With CD34+ Adult Bone Marrow Cells (2001) (57)
- The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias (2008) (57)
- Changing prevalence and severity of childhood allergic diseases in kyoto, Japan, from 1996 to 2006. (2009) (57)
- Hematopoietic Repopulating Ability of Cord Blood CD34+ Cells in NOD/Shi‐scid Mice (2000) (55)
- A human GM-CSF receptor expressed in transgenic mice stimulates proliferation and differentiation of hemopoietic progenitors to all lineages in response to human GM-CSF. (1995) (55)
- Early and late events in Fc epsilon RI signal transduction in human cultured mast cells. (1997) (54)
- Excess treatment reduction including anthracyclines results in higher incidence of relapse in core binding factor acute myeloid leukemia in children (2013) (53)
- Characteristics of histamine release from cultured human mast cells (1996) (53)
- Detection of Base Substitution-Type Somatic Mosaicism of the NLRP3 Gene with >99.9% Statistical Confidence by Massively Parallel Sequencing (2012) (53)
- In vitro expansion of the murine pluripotent hemopoietic stem cell population in response to interleukin 3 and interleukin 6. Application to bone marrow transplantation. (1989) (53)
- Stimulation of mouse connective tissue-type mast cells by hemopoietic stem cell factor, a ligand for the c-kit receptor. (1992) (53)
- Predicting response to immunosuppressive therapy in childhood aplastic anemia (2011) (52)
- Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis (2014) (51)
- Breastfeeding and the prevalence of allergic diseases in schoolchildren: Does reverse causation matter? (2010) (51)
- Thrombopoietin alone stimulates the early proliferation and survival of human erythroid, myeloid and multipotential progenitors in serum‐free culture (1997) (51)
- Orderly hematopoietic development of induced pluripotent stem cells via Flk‐1+ hemoangiogenic progenitors (2009) (50)
- Identification of cardiac stem cells with FLK1, CD31, and VE‐cadherin expression during embryonic stem cell differentiation (2005) (50)
- Induction of the high-affinity IgE receptor (Fc epsilon RI) on human mast cells by IL-4. (1996) (50)
- Inhibition of leukemic cell growth by a novel anti‐cancer drug (GUT‐70) from calophyllum brasiliense that acts by induction of apoptosis (2005) (49)
- Efficacy of recombinant human granulocyte colony-stimulating factor on neutropenia in patients with AIDS. (1990) (49)
- Human granulocyte colony-stimulating factor (G-CSF) stimulates the in vitro and in vivo development but not commitment of primitive multipotential progenitors from transgenic mice expressing the human G-CSF receptor. (1998) (48)
- Generation of Cardiac and Endothelial Cells from Neonatal Mouse Testis‐Derived Multipotent Germline Stem Cells (2007) (48)
- Expression of stromal cell-derived factor-1/pre-B cell growth-stimulating factor receptor, CXC chemokine receptor 4, on CD34+ human bone marrow cells is a phenotypic alteration for committed lymphoid progenitors. (1999) (48)
- Interleukin-6 enhances murine megakaryocytopoiesis in serum-free culture. (1990) (48)
- Infants with acute lymphoblastic leukemia and a germline MLL gene are highly curable with use of chemotherapy alone: results from the Japan Infant Leukemia Study Group. (2006) (47)
- Direct visualization of transplanted hematopoietic cell reconstitution in intact mouse organs indicates the presence of a niche. (2003) (46)
- Appropriate dose reduction in induction therapy is essential for the treatment of infants with acute myeloid leukemia: a report from the Japanese Pediatric Leukemia/Lymphoma Study Group (2013) (46)
- Soluble interleukin-6 (IL-6) receptor with IL-6 stimulates megakaryopoiesis from human CD34(+) cells through glycoprotein (gp)130 signaling. (1999) (46)
- Neutrophil differentiation from human‐induced pluripotent stem cells (2011) (45)
- Unexpectedly high prevalence of the mild form of propionic acidemia in Japan: presence of a common mutation and possible clinical implications (2002) (45)
- Peroxisome proliferator‐activated receptors are expressed in mouse bone marrow‐derived mast cells (2000) (45)
- Intracranial aneurysms in Ehlers-Danlos syndrome type IV in early childhood. (2001) (45)
- Preceding immunosuppressive therapy with antithymocyte globulin and ciclosporin increases the incidence of graft rejection in children with aplastic anaemia who underwent allogeneic bone marrow transplantation from HLA‐identical siblings (2006) (44)
- Expression of E2A-HLF chimeric protein induced T-cell apoptosis, B-cell maturation arrest, and development of acute lymphoblastic leukemia. (1999) (44)
- Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCID/γcnull mice through cell fusion (2007) (42)
- WASP is involved in proliferation and differentiation of human haemopoietic progenitors in vitro (1999) (42)
- Antiproliferative effect of IFN-gamma on proliferation of mouse connective tissue-type mast cells. (1990) (42)
- Infant leukemia in Japan: clinical and biological analysis of 48 cases. (1991) (42)
- Flk1(+) cardiac stem/progenitor cells derived from embryonic stem cells improve cardiac function in a dilated cardiomyopathy mouse model. (2007) (42)
- Autosomal Dominant Anhidrotic Ectodermal Dysplasia with Immunodeficiency Caused by a Novel NFKBIA Mutation, p.Ser36Tyr, Presents with Mild Ectodermal Dysplasia and Non-Infectious Systemic Inflammation (2013) (41)
- Identification and characterization of novel mutations of the major Fanconi anemia gene FANCA in the Japanese population (2004) (41)
- Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment (2010) (41)
- Novel Method for Efficient Production of Multipotential Hematopoietic Progenitors from Human Embryonic Stem Cells (2007) (40)
- Methylation status of the p15 and p16 genes in paediatric myelodysplastic syndrome and juvenile myelomonocytic leukaemia (2005) (40)
- Living-related liver transplantation for neonatal-onset propionic acidemia. (2000) (40)
- Treatment of the anemia of aplastic anemia patients with recombinant human erythropoietin in combination with granulocyte colony ‐ stimulating factor: a multicenter randomized controlled study (1997) (40)
- MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1 (2018) (39)
- Correction of immunodeficiency associated with NEMO mutation by umbilical cord blood transplantation using a reduced-intensity conditioning regimen (2007) (38)
- Allergic status of schoolchildren with food allergy to eggs, milk or wheat in infancy (2009) (37)
- A review of 125 cases to determine the risk of myelodysplasia and leukemia in pediatric neutropenic patients after treatment with recombinant human granulocyte colony-stimulating factor. (1994) (36)
- Long-term extensive expansion of mouse hepatic stem/progenitor cells in a novel serum-free culture system. (2005) (36)
- Molecular and clinical analyses of Japanese patients with carbamoylphosphate synthetase 1 (CPS1) deficiency (2007) (36)
- Rapid diagnosis of FHL3 by flow cytometric detection of intraplatelet Munc13-4 protein. (2011) (36)
- Regulation of human FcϵRI β chain gene expression by Oct‐1 (2003) (36)
- Induction of mixed erythroid-megakaryocyte colonies and bipotential blast cell colonies by recombinant human erythropoietin in serum-free culture. (1990) (35)
- The CD40-CD40L axis and IFN-γ play critical roles in Langhans giant cell formation. (2012) (35)
- Effects of interleukin-6 on hematopoiesis in bone marrow-transplanted mice. (1989) (35)
- Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells (2016) (35)
- Role of the Microenvironment of the Embryonic Aorta‐Gonad‐Mesonephros Region in Hematopoiesis (2001) (35)
- Early Development of Definitive Erythroblasts from Human Pluripotent Stem Cells Defined by Expression of Glycophorin A/CD235a, CD34, and CD36 (2016) (35)
- Characterization of peripheral blood progenitor cells (PBPC) mobilized by filgrastim (rHuG‐CSF) in normal volunteers: dose–effect relationship for filgrastim with the character of mobilized PBPC (1996) (35)
- Pluripotent stem cell models of Blau syndrome reveal an IFN‐&ggr;–dependent inflammatory response in macrophages (2018) (35)
- iPSC-derived functional human neuromuscular junctions model the pathophysiology of neuromuscular diseases. (2019) (35)
- Stimulation of Mouse and Human Primitive Hematopoiesis by Murine Embryonic Aorta-Gonad-Mesonephros–Derived Stromal Cell Lines (1998) (35)
- Outcome of childhood acute lymphoblastic leukemia with induction failure treated by the Japan Association of Childhood Leukemia Study (JACLS) ALL F‐protocol (2010) (35)
- Impaired neutrophil maturation in truncated murine G-CSF receptor-transgenic mice. (2003) (35)
- Mislocalization of syntaxin‐1 and impaired neurite growth observed in a human iPSC model for STXBP1‐related epileptic encephalopathy (2016) (34)
- Single-cell origin of human mixed hemopoietic colonies expressing various combinations of cell lineages. (1985) (34)
- PBSC collection from family donors in Japan: a prospective survey (2014) (34)
- Stimulation of connective tissue-type mast cell proliferation by crosslinking of cell-bound IgE (1989) (34)
- Relapse of aplastic anemia in children after immunosuppressive therapy: a report from the Japan Childhood Aplastic Anemia Study Group (2011) (34)
- Current Knowledge on the Pathophysiology of Fanconi Anemia: From Genes to Phenotypes (2001) (33)
- Characterization of chronic idiopathic thrombocytopenic purpura in Japanese children: a retrospective multi-center study (2010) (33)
- A neurosphere-derived factor, cystatin C, supports differentiation of ES cells into neural stem cells. (2006) (33)
- Synergism of interferon-gamma and stem cell factor on the development of murine hematopoietic progenitors in serum-free culture. (1993) (33)
- Reconstitution of human haematopoiesis in non‐obese diabetic/severe combined immunodeficient mice by clonal cells expanded from single CD34+CD38– cells expressing Flk2/Flt3 (2002) (32)
- Mesenchymal mode of migration participates in pulmonary metastasis of mouse osteosarcoma LM8 (2010) (32)
- Generation of induced pluripotent stem (iPS) cells derived from a murine model of Pompe disease and differentiation of Pompe-iPS cells into skeletal muscle cells. (2011) (31)
- Living-donor liver transplantation for propionic acidaemia (2004) (31)
- Enhanced Chondrogenesis of Induced Pluripotent Stem Cells From Patients With Neonatal‐Onset Multisystem Inflammatory Disease Occurs via the Caspase 1–Independent cAMP/Protein Kinase A/CREB Pathway (2015) (31)
- Preserved High Probability of Overall Survival with Significant Reduction of Chemotherapy for Myeloid Leukemia in Down Syndrome: A Nationwide Prospective Study in Japan (2016) (31)
- Improvement in bronchiolitis obliterans organizing pneumonia in a child after allogeneic bone marrow transplantation by a combination of oral prednisolone and low dose erythromycin (2000) (31)
- Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors (2015) (31)
- Frequent somatic mosaicism of NEMO in T cells of patients with X-linked anhidrotic ectodermal dysplasia with immunodeficiency. (2012) (31)
- Identification of Hepatic Niche Harboring Human Acute Lymphoblastic Leukemic Cells via the SDF-1/CXCR4 Axis (2011) (31)
- Inhibitory effect of adenosine on degranulation of human cultured mast cells upon cross-linking of Fc epsilon RI. (1998) (31)
- A conditioning regimen of busulfan, fludarabine, and melphalan for allogeneic stem cell transplantation in children with juvenile myelomonocytic leukemia (2008) (30)
- Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition (2018) (30)
- Role of Bone Marrow–Derived Progenitor Cells in Cuff-Induced Vascular Injury in Mice (2004) (30)
- Two common founder mutations of the fanconi anemia group g gene FANCG/XRCC9 in the Japanese population (2003) (30)
- Interferon‐γ promotes the survival and FcεRI‐mediated histamine release in cultured human mast cells (1996) (30)
- Identification and Characterization of Hemoangiogenic Progenitors During Cynomolgus Monkey Embryonic Stem Cell Differentiation (2006) (30)
- The effect of past food avoidance due to allergic symptoms on the growth of children at school age. (2010) (30)
- Differential Requirement for the CD40-CD154 Costimulatory Pathway during Th Cell Priming by CD8α+ and CD8α− Murine Dendritic Cell Subsets1 (2004) (29)
- Spontaneous production of interleukin-6 by Ki-1-positive large-cell anaplastic lymphoma with extensive bone destruction. (1991) (29)
- Hereditary hemolytic anemia caused by diverse point mutations of pyruvate kinase gene found in Japan and Hong Kong (1994) (29)
- Cytokines Regulate Development of Human Mast Cells from Hematopoietic Progenitors (2002) (28)
- Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models (2016) (28)
- Differential effects of human granulocyte colony-stimulating factor (hG-CSF) and thrombopoietin on megakaryopoiesis and platelet function in hG-CSF receptor-transgenic mice. (1999) (28)
- Clonal origin of human erythro-eosinophilic colonies in culture (1982) (28)
- Measurement of endogenous plasma granulocyte colony-stimulating factor in patients with acquired aplastic anemia by a sensitive chemiluminescent immunoassay. (1996) (28)
- RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells (2018) (28)
- Long‐Term Culture of Postnatal Mouse Hepatic Stem/Progenitor Cells and Their Relative Developmental Hierarchy (2007) (28)
- Ex vivo expansion of human hematopoietic stem cells. (2001) (27)
- Thrombopoietin‐independent effect of interferon‐γ on the proliferation of human megakaryocyte progenitors (1997) (27)
- Long-term survival after nonintensive chemotherapy in some juvenile myelomonocytic leukemia patients with CBL mutations, and the possible presence of healthy persons with the mutations. (2010) (27)
- A potential molecular approach to ex vivo hematopoietic expansion with recombinant epidermal growth factor receptor-expressing adenovirus vector. (1998) (27)
- Hypercalcemia associated with all-trans-retinoic acid in the treatment of acute promyelocytic leukemia. (1993) (27)
- Viral Infections in Juvenile Myelomonocytic Leukemia: Prevalence and Clinical Implications (2004) (27)
- Stem Cell Plasticity in the Hematopoietic System (2004) (27)
- The Bcr-Abl Kinase Inhibitor INNO-406 Induces Autophagy and Different Modes of Cell Death Execution in Bcr-Abl-Positive Leukemias. (2007) (27)
- Bone marrow engraftment but limited expansion of hematopoietic cells from multipotent germline stem cells derived from neonatal mouse testis. (2009) (26)
- Loss of Borealin/DasraB leads to defective cell proliferation, p53 accumulation and early embryonic lethality (2008) (26)
- Hematopoietic and lymphopoietic responses in human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor transgenic mice injected with human GM-CSF. (1997) (26)
- Gene expression profiles of human small airway epithelial cells treated with low doses of 14- and 16-membered macrolides. (2001) (26)
- Detection of myelodysplastic syndrome/ acute myeloid leukemia evolving from aplastic anemia in children, treated with recombinant human G-CSF. (2003) (26)
- Exclusive expression of G‐CSF receptor on myeloid progenitors in bone marrow CD34+ cells (2000) (25)
- Direct Development of Functionally Mature Tryptase/Chymase Double‐Positive Connective Tissue‐Type Mast Cells from Primate Embryonic Stem Cells (2008) (25)
- Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress (2018) (24)
- Molecular and clinical analysis of Japanese patients with 3-hydroxy-3-methylglutaryl CoA lyase (HL) deficiency (2000) (24)
- Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA. (2017) (24)
- Ttyh1, a Ca2+‐binding protein localized to the endoplasmic reticulum, is required for early embryonic development (2010) (24)
- Effects of interleukin-3 and interleukin-4 on the development of "connective tissue-type" mast cells: interleukin-3 supports their survival and interleukin-4 triggers and supports their proliferation synergistically with interleukin-3. (1990) (24)
- Multiple Reversions of an IL2RG Mutation Restore T cell Function in an X-linked Severe Combined Immunodeficiency Patient (2012) (24)
- Noninvasive ventilation for pediatric patients under 1 year of age after cardiac surgery. (2007) (24)
- Successful treatment of a patient with Klinefelter's syndrome complicated by mediastinal germ cell tumor and AML(M7) (2008) (23)
- Development of human lymphohematopoietic stem and progenitor cells defined by expression of CD34 and CD81. (2001) (23)
- Effects of long-term treatment with recombinant human granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome. (1995) (23)
- Genetically mast cell-deficient W/Wv mice as a tool for studies of differentiation and function of mast cells. (1987) (23)
- Human cord blood CD34+ cells develop into hepatocytes in the livers of NOD/SCID/gamma(c)null mice through cell fusion. (2007) (23)
- In vitro expansion of CD34+CD38− cells under stimulation with hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia (2014) (22)
- Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome–Positive Lymphoid Leukemia (2015) (22)
- Cyclin‐dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes (2011) (22)
- A novel variant fibrinogen, deletion of Bbeta111Ser in coiled-coil region, affecting fibrin lateral aggregation. (2006) (22)
- Granulocyte colony-stimulating factor protects cardiac mitochondria in the early phase of cardiac injury. (2009) (22)
- Massive pericardial and pleural effusion with anasarca following allogeneic bone marrow transplantation. (2000) (22)
- Clonal selection in xenografted TAM recapitulates the evolutionary process of myeloid leukemia in Down syndrome. (2013) (21)
- Clinical characteristics and treatment outcome in 65 cases with refractory cytopenia of childhood defined according to the WHO 2008 classification (2014) (21)
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- Dandy-Walker variant in Coffin-Siris syndrome. (2001) (21)
- A case of early-onset sarcoidosis with a six-base deletion in the NOD2 gene. (2010) (21)
- Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells (2017) (21)
- Current Status of Hematopoietic Cell Transplantation for Adult Patients with Hematologic Diseases and Solid Tumors in Japan (2006) (21)
- Successful T-cell-replete peripheral blood stem cell transplantation from HLA-haploidentical microchimeric mother to daughter with refractory acute lymphoblastic leukemia using reduced-intensity conditioning (2003) (21)
- Specific recruitment of SPA-1 to the immunological synapse: involvement of actin-bundling protein actinin. (2004) (21)
- Role of bone marrow-derived progenitor cells in cuff-induced vascular injury in mice. (2004) (21)
- Apoptosis Induced by Molecular Targeting Therapy in Hematological Malignancies (2003) (21)
- Increased Susceptibility to Severe Chronic Liver Damage in CXCR4 Conditional Knock-Out Mice (2012) (20)
- Possible role of stem cell factor as a serum factor: monoclonal anti-c-kit antibody abrogates interleukin-6-dependent colony growth in serum-containing culture. (1993) (20)
- Involvement of Extracellular Signal-Regulated Kinase Activation in Human Osteosarcoma Cell Resistance to the Histone Deacetylase Inhibitor FK228 [(1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone] (2009) (20)
- Stem Cell Factor Has a Suppressive Activity to IgE-Mediated Chemotaxis of Mast Cells1 (2005) (20)
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- Establishment of isogenic iPSCs from an individual with SCN1A mutation mosaicism as a model for investigating neurocognitive impairment in Dravet syndrome (2016) (20)
- Stem cell factor enhances the growth of primitive erythroid progenitors to a greater extent than interleukin‐3 in patients with aplastic anaemia (1993) (20)
- Cerebral infarction and pancreatitis: possible complications of patients with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency (2000) (19)
- Limited Ability of Antigen-Specific Th1 Responses to Inhibit Th2 Cell Development In Vivo1 (2005) (19)
- Interferon‐Gamma inhibits proliferation, but not commitment, of murine granulocyte‐macrophage progenitors (1992) (19)
- B cell potential can be obtained from pre-circulatory yolk sac, but with low frequency. (2007) (19)
- Reference intervals for serum granulocyte colony-stimulating factor levels in children. (1996) (18)
- Differential requirement for the CD40-CD154 costimulatory pathway during Th cell priming by CD8 alpha+ and CD8 alpha- murine dendritic cell subsets. (2004) (18)
- Mitochondrial dysfunction is related to necrosis-like programmed cell death induced by A23187 in CEM cells. (2005) (18)
- Cyclin-Dependent Kinase Inhibitors During Human Hematopoiesis (1999) (18)
- Hereditary hemolytic anemia caused by diverse point mutations of pyruvate kinase gene found in Japan and Hong Kong. (1994) (18)
- Establishment of real-time polymerase chain reaction method for quantitative analysis of asparagine synthetase expression. (2004) (18)
- Second Transplantation from HLA 2-Loci-Mismatched Mother for Graft Failure Due to Hemophagocytic Syndrome after Cord Blood Transplantation (2004) (18)
- Risk-adjusted therapy for pediatric non-T cell ALL improves outcomes for standard risk patients: results of JACLS ALL-02 (2020) (18)
- Two Different Roles of Purified CD45+c‐Kit+Sca‐1+Lin− Cells After Transplantation in Muscles (2005) (18)
- YM477, a Novel Orally-Active Thrombopoietin Receptor Agonist. (2005) (18)
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- Successful hematopoietic stem cell transplantation for aplastic anemia following living-related liver transplantation (2002) (17)
- Multicolor Staining of Globin Subtypes Reveals Impaired Globin Switching During Erythropoiesis in Human Pluripotent Stem Cells (2014) (17)
- Successful autologous peripheral blood stem cell transplantation with a double‐conditioning regimen for recurrent hepatoblastoma after liver transplantation (2009) (17)
- Subclinical central pontine myelinolysis following liver transplantation (2002) (17)
- CD146 is a novel marker for highly tumorigenic cells and a potential therapeutic target in malignant rhabdoid tumor (2016) (17)
- Successful cord blood transplantation using a reduced‐intensity conditioning regimen for advanced childhood‐onset cerebral adrenoleukodystrophy (2009) (17)
- Fibrillin I gene polymorphism is associated with tall stature of normal individuals (2006) (16)
- Adipocytokines in childhood cancer survivors and correlation with metabolic syndrome components (2013) (16)
- Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate (2018) (16)
- Stochastic model for mast cell proliferation in culture of murine peritoneal cells (1989) (16)
- Treatment of children with refractory anemia: The Japanese Childhood MDS Study Group trial (MDS99) (2009) (16)
- Stochastic model for multipotent hemopoietic progenitor differentiation (1989) (16)
- alpha4-Integrin(+) endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells. (2006) (15)
- Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors. (2001) (15)
- Rapid Improvement of Paraplegia Caused by Epidural Involvements of Burkitt’s Lymphoma With Chemotherapy (2004) (15)
- Human pluripotent stem cell–derived erythropoietin-producing cells ameliorate renal anemia in mice (2017) (15)
- Immunohistochemical demonstration of inter-α-trypsin inhibitor light chain (bikunin) in human mast cells (1999) (15)
- Notch ligand Delta‐1 differentially modulates the effects of gp130 activation on interleukin‐6 receptor α‐positive and ‐negative human hematopoietic progenitors (2007) (15)
- IL‐6 and SCF exert different effects on megakaryocyte maturation (1998) (15)
- A pediatric case of transfusion‐related acute lung injury following bone marrow infusion (2007) (15)
- Induction of human pluripotent stem cell-derived natural killer cells for immunotherapy under chemically defined conditions. (2019) (15)
- Efficient assay for evaluating human thrombopoiesis using NOD/SCID mice transplanted with cord blood CD34+ cells (2006) (14)
- Induction of granulocyte and granulocyte‐macrophage colony‐stimulating factors from human monocytes stimulated by Fc fragments of human IgG (1991) (14)
- Retrovirus vectors designed for efficient transduction of cytotoxic or cytostatic genes (1999) (14)
- CD34+CD7+ leukemic progenitor cells may be involved in maintenance and clonal evolution of chronic myeloid leukemia. (2005) (14)
- Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype: a study by the Japanese Childhood AML Cooperative Study Group (2010) (14)
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- Synergistic action of interleukin-10 (IL-10) with IL-3, IL-4 and stem cell factor on colony formation from murine mast cells in culture. (1995) (13)
- High event‐free survival rate with minimum‐dose‐anthracycline treatment in childhood acute promyelocytic leukaemia: a nationwide prospective study by the Japanese Paediatric Leukaemia/Lymphoma Study Group (2016) (13)
- RUNX transcription factors potentially control E-selectin expression in the bone marrow vascular niche in mice. (2018) (13)
- Establishment of human granulocyte‐macrophage colony stimulating factor producing transgenic SCID mice (1996) (13)
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- Successful Abolition of Prophylactic Cranial Irradiation in Children with Non-T Acute Lymphoblastic Leukemia (ALL) in the Japan Association of Childhood Leukemia Study (JACLS) ALL-02 Trial (2011) (13)
- Clinical characteristics of 15 children with juvenile myelomonocytic leukaemia who developed blast crisis: MDS Committee of Japanese Society of Paediatric Haematology/Oncology (2014) (13)
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- Familial hemophagocytic lymphohistiocytosis with the MUNC13-4 mutation: a case report (2006) (12)
- Sca-1+ endothelial cells (SPECs) reside in the portal area of the liver and contribute to rapid recovery from acute liver disease. (2008) (12)
- A novel aspect of the maturational step of megakaryocytes in thrombopoiesis: bundle formation of microtubules in megakaryocytes. (1996) (12)
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- Stem cell factor promotes proliferation of human primitive megakaryocytic progenitors, but not megakaryocytic maturation. (1994) (11)
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- Possible dual effect of CD14 molecule on atopy. (2002) (11)
- Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) after chemotherapy in patients with non-Hodgkin's lymphoma; a placebo-controlled double blind phase III trial. (1993) (11)
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- Inhibitory effect of interleukin 3 on early development of human B‐lymphopoiesis (2001) (11)
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- Circulating eosinophil colony-forming cells in pure eosinophil aplasia. (1984) (11)
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- Lipid A Analogue, ONO-4007, Inhibits IgE Response and Antigen-Induced Eosinophilic Recruitment into Airways in BALB/c Mice (2002) (10)
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- Recipient seropositivity for adenovirus type 11 (AdV11) is a highly predictive factor for the development of AdV11-induced hemorrhagic cystitis after allogeneic hematopoietic SCT (2013) (9)
- HOX decoy peptide enhances the ex vivo expansion of human umbilical cord blood CD34+ hematopoietic stem cells/hematopoietic progenitor cells. (2006) (9)
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- Anti-A b Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer ’ s Disease (2011) (7)
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- Effect of a Chymotrypsin‐like Inhibitor, TPCK, on Histamine Release from Cultured Human Mast Cells (1997) (6)
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- Dasatinib induces autophagy in mice with Bcr-Abl-positive leukemia (2017) (6)
- Response to Comment on “Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells” (2013) (6)
- Two homozygous cases of erythrocyte pyruvate kinase (PK) deficiency in Japan: PK sendai and PK shinshu (1988) (6)
- Serum granulocyte colony‐stimulating factor levels in patients with chronic neutropenia of childhood: modulation of G‐CSF levels by myeloid precursor cell mass (1999) (6)
- Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythroblasts (2022) (6)
- Cytokine requirement for the development of T‐lymphoid lineage potential in clonal lymphohaematopoietic progenitors in vitro (2000) (6)
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- Partial seizures in leukoencephalopathy with swelling and a discrepantly mild clinical course (2000) (5)
- Risk-Adjusted Therapy of Acute Lymphoblastic Leukemia Can Optimize the Indication of Stem Cell Transplantation and Cranial Irradiation: Results of Japan Association Childhood Leukemia Study Group (JACLS) Protocol ALL-02 (2016) (5)
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- Acid-suppressing Drugs and a Low 1 Level of Antithrombin as Risk Factors for L-Asparaginase-associated Pancreatitis: A Case-control Study in the Japan Association of Childhood Leukemia Study (JACLS) (2018) (2)
- Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model (2019) (2)
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- Microarray analyses of otospheres derived from the cochlea in the inner ear identify putative transcription factors that regulate the characteristics of otospheres (2017) (2)
- Prospective, Randomized, Multicenter Study Comparing Antithymocyte Globulin (ATG) Alone with ATG Plus Cyclosporine (CsA) for Treatment of Children with Nonsevere Aplastic Anemia (nSAA). (2005) (2)
- [Elevated production of GM-CSF by peripheral blood mononuclear cells stimulated with mite antigens in children with bronchial asthma]. (1992) (2)
- Multipotential hemopoietic colonies in single-cell cultures. (1984) (2)
- Chimeric cytokine receptor can transduce expansion signals in interleukin 6 receptor alpha (IL-6Ralpha)-, IL-11Ralpha-, and gp130-low to -negative primitive hematopoietic progenitors. (1999) (2)
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- Role of Soluble Interleukin-6 Receptor With Interleukin-6 in Human Hematopoiesis. (1997) (1)
- Generation of germ-free common marmosets (2021) (1)
- Abstract 1020: Cyclin-dependent Kinase-9, As A Novel Component Of p300/GATA4 Complex, Is Involved In The Differentiation Of Mouse ES Cells Into Cardiac Myocytes (2007) (1)
- Generation of disease-specific induced pluripotent stem cells from sporadic Parkinson's disease patients (2011) (1)
- Autoinflammatory diseases - a new entity of inflammation (2011) (1)
- [Studies on the fragments of FDP in 3 patients with DIC associated with acute promyelocytic leukemia]. (1993) (1)
- OP0011 Induced Pluripotent Stem Cell-Derived Monocytic Cell Lines from Congenital Immunological Disorders Serve A Versatile Platform for Phenotype-Based Compound Screening (2016) (1)
- Reduced Production of Mature Neutrophils From Induced Pluripotent Stem Cells Derived From a Severe Congenital Neutropenia Patient with HAX1 Gene Deficiency (2011) (1)
- Bisphosphonate Zoledronic Acid (ZOL) Inhibits the Abnormal Proliferation and Differentiation of Juvenile Myelomonocytic Leukemia (JMML) Cells. (2004) (1)
- Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythrocytes (2021) (1)
- [Abnormal hemopoiesis in juvenile chronic myelogenous leukemia: phagocytic cell-dependent endogenous colony formation by peripheral blood and bone marrow cells]. (1985) (1)
- N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21 (2021) (1)
- Efficacy of a combination therapy targeting CDK4/6 and autophagy in a mouse xenograft model of t(8;21) acute myeloid leukemia (2021) (1)
- JACLS ALL-02 SR protocol reduced-intensity chemotherapy produces excellent outcomes in patients with low-risk childhood acute lymphoblastic leukemia (2022) (1)
- Hematopoietic stem cell transplantation (HSCT) for juvenile myelomonocytic leukemia (JMML) (2006) (1)
- The combination of ruxolitinib and Bcl-2/Mcl-1 inhibitors has a synergistic effect on leukemic cells carrying a SPAG9::JAK2 fusion. (2022) (1)
- A CIAS1 mutation in a Japanese girl with familial cold autoinflammatory syndrome (2008) (1)
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- A Novel Method for Efficient Production of Multipotential Hematopoietic Progenitors from Human Embryonic Stem Cells by Co-Culture with Murine Fetal Liver-Derived Stromal Cells. (2005) (1)
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- The first Japanese biobank of patient‐derived pediatric acute lymphoblastic leukemia xenograft models (2022) (1)
- High Event-Free Survival Rate with Minimum-Dose-Anthracycline Treatment in Childhood Acute Promyelocytic Leukemia: A Nationwide Prospective Study By the Japanese Pediatric Leukemia / Lymphoma Study Group (JPLSG) (2014) (1)
- Expression of E 2 A-HLF Chimeric Protein Induced T-Cell Apoptosis , B-Cell Maturation Arrest , and Development of Acute Lymphoblastic Leukemia (1999) (1)
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- Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model (2019) (0)
- Primary immunodeficiency (WS-051) Chairpersons: Toshio Miyawaki, Michelle Letarte (2010) (0)
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- Title Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells (2018) (0)
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- Title Enhanced Chondrogenesis of Induced Pluripotent Stem Cells From Patients With Neonatal-Onset Multisystem Inflammatory Disease Occurs via the Caspase 1-Independent cAMP / Protein Kinase (2019) (0)
- Author Correction: A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice (2022) (0)
- P-88 Methylation status of the P15 and P16 genes in pediatric myelodysplastic syndrome and juvenile myelomonocytic leukemia (2005) (0)
- Synergistic Interaction between Notch ligand Delta-1 and IL-6/Soluble IL-6 Receptor Fusion Protein in the Generation of BFU-E from Primitive Hematopoietic Progenitors. (2004) (0)
- 983 Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress (2018) (0)
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- stimulated production of platelets In vivo effects of recombinant human interleukin-6 in primates: (2011) (0)
- syndrome B activation: common genetic etiology with Blau κ nuclear factor- Early-onset sarcoidosis and CARD15 mutations with constitutive (2013) (0)
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- Different Kinetics and Function of Vascular Endothelial Growth Factor Recepotor-1 and −2 during Hemangioblast Development from Primate Embryonic Stem Cells. (2006) (0)
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- anemia second-line treatment for children with severe and very severe aplastic therapy with stem cell transplantation from an alternative donor as Prospective multicenter trial comparing repeated immunosuppressive (2013) (0)
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- A Specific Inhibitor of Histone Deacetylase, Trichostatin A, Promotes Differentiation of Embryonic Stem Cells into Cardiac Myocytes (2003) (0)
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- Functional expressions of chemokine receptor CXCR4 for cord blood CD34+ cells differ from those for adult bone marrow and peripheral blood cells in culture (1999) (0)
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- High-throughput Screening with Pluripotent Stem Cells Identifies CUDC-907 as an Effective Compound for Restoring the Proinflammatory Phenotype of Nakajo-Nishimura Syndrome (2020) (0)
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- 23 A CASE OF FOCAL NESIDIOBLASTOSIS TREATED WITH PARTIAL PANCREATECTOMY (2003) (0)
- Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate (2018) (0)
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- Embryonic endothelial cells vary in their bematopoietic potential and surface phenotype (2008) (0)
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- transgenic mice − Impaired neutrophil maturation in truncated murine G-CSF receptor (2003) (0)
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- changes during developmental stages CD34 expression on long-term repopulating hematopoietic stem cells (2013) (0)
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- Total and LDL Cholesterol Are Associated with Atopic Status in Schoolchildren (2010) (0)
- P-100 Allogeneic hematopoietic stem cell transplantation (HSCT) for myelodysplastic syndrome (MDS)/acute myeloid leukemia (AML) evolved from aplastic anemia (AA) in childhood (2005) (0)
- Early-onset sarcoidosis and NOD2: Summary on genetic analysis of Japanese 10 cases (2005) (0)
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- Aberrations of Genes Regulating NF Kappa B Pathway in B-Cell Malignant Lymphoma. (2009) (0)
- (cid:1) 4-Integrin (cid:2) endothelium derived from primate embryonic stem cells generates primitive and definitive hematopoietic cells (2007) (0)
- 501 Elevated IgE production in mice lacking the Id2 gene (2000) (0)
- 74 AN ASSOCIATION OF THE FBN1 GENE POLYMORPHISM WITH TALL STATURE (2003) (0)
- Mesodermal Development From Reprogrammed Fanconi Anemia Cells Is Affected by ALDH2 Enzymatic Activity (2012) (0)
- Severe Adverse Events of Allogeneic Related Peripheral Blood Stem Cell Donors -Results of Nation-Wide 3,262 Consecutively and Prospectively Registered Case-Survey in Japan and of Its Comparison to the Outcome of Retrospective Survey Shared with EBMT for Stem Cell Donors. (2005) (0)
- Autonomous feedback loop of RUNX1-p53-CBFB in acute myeloid leukemia cells (2017) (0)
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- [Not Available]. (2003) (0)
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- G-CSF Receptor Multipotential Progenitors From Transgenic Mice Expressing the Human Vitro and In Vivo Development But Not Commitment of Primitive Human Granulocyte Colony-Stimulating Factor (G-CSF) Stimulates the In (2010) (0)
- Induction of astrocyte differentiation from human induced pluripotent stem cells carrying mutant SOD1 (2011) (0)
- Diagnosis of NLRP3 somatic mosaicism in CINCA/NOMID patients using next-generation sequencing (2011) (0)
- Avoidance of reintubation by using sedation during noninvasive positive pressure ventilation in a 3-month-old infant with postoperative respiratory failure. (2010) (0)
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- Reconstitution of NK Cell Receptor Repertoire after Pediatric Stem Cell Transplantation. (2004) (0)
- Correction of Immunodeficiency Associated with NEMO Mutation by Umbilical Cord Stem Cell Transplantation Using a Reduced-Intensity Conditioning Regimen. (2006) (0)
- [Differentiation of fibrinolysis and fibrinogenolysis by analysis of FDP fragments]. (1992) (0)
- RUNX1 positively regulates the ErbB2/HER2 signaling pathway through modulating SOS1 expression in gastric cancer cells (2018) (0)
- Continuous Cytarabine Plus Dexamethasone in Consolidation Phase to Patients with Childhood ALL: Result from Japan Association of Childhood Leukemia Study - JACLS ALL02 Protocol - (2016) (0)
- Exploring the Pathogenesis of Down Syndrome-Related Myeloproliferative Disorders Using iPSCs (2014) (0)
- Common Marmoset as a New Preclinical Animal Model for Human Gene Therapy of Hematological Disorders (1996) (0)
- A case of severe childhood aplastic anemia associated with lymphocyte mediated hemopoietic suppression: recovery following cyclophosphamide treatment. (1983) (0)
- Megakaryocytes Human Platelets and Its' Intracellular Expression in Human Functional Expression of the High Affinity Receptor for IgE (Fc?RI) in (2013) (0)
- New “The Japanese Society of Inflammation and Regeneration” with you (2005) (0)
- The Significance of BAALC Expression and CEBPa Mutations as New Prognostic Factors in Pediatric Acute Myeloid Leukemia with Normal Karyotype. (2006) (0)
- [Two cases of childhood acute lymphoblastic leukemia with osteoporosis and vertebral compression fractures]. (1986) (0)
- Disease Modeling and Drug Discovery Using Induced Pluripotent Stem Cells From CINCA Syndrome Patients (2012) (0)
- Correction: Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity (2021) (0)
- Risk-adjusted therapy for pediatric non-T cell ALL improves outcomes for standard risk patients: results of JACLS ALL-02 (2020) (0)
- activity necrosis-like programmed cell death mediated by serine protease positive human leukemic cells: caspase-independent, - BCR-ABL induced cell death of - A novel mechanism for imatinib mesylate (2013) (0)
- Sensitive in vivo Assay System for Human Stem Cells Using NOD/SCID/γcnull mice (2005) (0)
- [Cytokine regulation of hemopoietic stem cell proliferation]. (1991) (0)
- Four cases of osteosarcoma in children aged less than six years at diagnosis : Experience of the Kyoto University Hospital (2009) (0)
- [Clinical evaluation of effects of KRN8601 (rhG-CSF) on neutropenia]. (1992) (0)
- RUNX1–Survivin Axis Is a Novel Therapeutic Target for Malignant Rhabdoid Tumors (2022) (0)
- Murine Dendritic Cell Subsets − α and CD 8 + α Th Cell Priming by CD 8 CD 40-CD 154 Costimulatory Pathway during Differential Requirement for the Tatsutoshi (2004) (0)
- Regulation of human Fc e RI b chain gene expression by Oct-1 (2003) (0)
- [Granulocyte colony-stimulating factor combination therapy of acute myeloid leukemia complicated with severe infection]. (1994) (0)
- [Childhood t(8;21) acute myelocytic leukemia: a comparison of clinical features and risk factors with adult cases]. (2001) (0)
- [Continuous infusion of cyclosporine A and C3 monitoring in pediatric stem cell transplantation]. (2007) (0)
- Title The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells (2016) (0)
- A Comparison of Myelopoiesis from Induced Pluripotent Stem Cells with a Mutation in ELANE between Cyclic Neutropenia and Severe Congenital Neutropenia (2015) (0)
- JSCN ICNC 2016 Travel Award (2016) (0)
- Successful Treatment with Multi-Antifungal Agents Including Voriconazole for Two Cases Developing Severe Aspergillus Infection after Bone Marrow Transplantation (2008) (0)
- PSC-Derived Hematopoietic System to Elucidate the Cooperation Between Gene Alterations and Cell Lineages in Leukemogenesis (2016) (0)
- CD34CD7 Leukemic Progenitor Cells May Be Involved in Maintenance and Clonal Evolution of Chronic Myeloid Leukemia (2005) (0)
- Earlier initiation of GH therapy does not influence adult height but enables earlier start of pubertal induction in children with multiple pituitary hormone deficiency (2004) (0)
- Case report Non-progressive viral myelitis in X-linked agammaglobulinemia (2002) (0)
- [An improved culture method without human plasma for megakaryocyte colony formation: megakaryocyte colony forming cells (CFU-M) in human umbilical cord blood]. (1985) (0)
- Wnt/β-Catenin Pathway Affects the Cell-Fate Decisions of Hematopoietic Stem/Progenitor Cells Modulating the Epigenetic States of Various Essential Transcription Factors (2008) (0)
- Iconographies supplémentaires de l'article : Human granulocyte-macrophage colony-stimulating factor (hGM-CSF)–dependent in vitro and in vivo proliferation and differentiation of all hematopoietic progenitor cells in hGM-CSF receptor transgenic mice (2011) (0)
- [In vitro studies on proliferation and differentiation of bone marrow hematopoietic cells in children (author's transl)]. (1974) (0)
- Antithymocyte Globulin (ATG), Cyclosporine (CyA), and Danazol Versus ATG and CyA As Treatment for Children with Aplastic Anemia: Result of Matched-Pair Analysis (2011) (0)
- P-115 Bisphosphonate zoledronicacid (ZOL) inhibits the abnormal proliferation and differentiation of juvenile myelomonocytic leukemia (JMML) cells (2005) (0)
- Use of hepatocyte growth factor for the preparation of a reproduction system for hematopoietic stem cells (1992) (0)
- Identification of Candidate Progenitor Populations Which Causes Transient Abnormal Myelopoiesis (2017) (0)
- Pluripotent stem cell models of reticular dysgenesis as a tool for elucidating the potential role of intracellular bioenergetic systems on controlling the fate of hematopoietic progenitors (2015) (0)
- Development of an osteosarcoma model with MYCN amplification and TP53 mutation in hiPS cell‐derived neural crest cells (2023) (0)
- Efficient derivation of sympathetic neurons from human pluripotent stem cells with a defined condition (2018) (0)
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What Schools Are Affiliated With Tatsutoshi Nakahata?
Tatsutoshi Nakahata is affiliated with the following schools: