Tetsuya Terasaki

Q: What Schools Are Affiliated With Tetsuya Terasaki

Tetsuya Terasaki is affiliated with the following schools: Hokkaido University, Tohoku University, Kanazawa University, University of Tokyo, Kurume University, Kumamoto University, Osaka University, Kyoto University

Tetsuya Terasaki's AcademicInfluence.com Rankings

Tetsuya Terasaki

Physics

#6081

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#7984

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Physics

Tetsuya Terasaki's Degrees

PhD Physics University of Tokyo
Masters Physics University of Tokyo
Bachelors Physics University of Tokyo

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Tetsuya Terasaki's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Quantitative targeted absolute proteomics of human blood–brain barrier transporters and receptors (2011) (684)
Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria (2008) (460)
Simultaneous Absolute Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases as a Novel Approach for the Characterization of Individual Human Liver: Comparison with mRNA Levels and Activities (2012) (420)
Contribution of Carrier-Mediated Transport Systems to the Blood–Brain Barrier as a Supporting and Protecting Interface for the Brain; Importance for CNS Drug Discovery and Development (2007) (417)
Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels. (2011) (335)
A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro (2004) (323)
P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells. (1992) (288)
Brain efflux index as a novel method of analyzing efflux transport at the blood-brain barrier. (1996) (237)
Inducible nitric oxide synthase isoform is a key mediator of leukostasis and blood-retinal barrier breakdown in diabetic retinopathy. (2007) (235)
Thioredoxin interacting protein (TXNIP) induces inflammation through chromatin modification in retinal capillary endothelial cells under diabetic conditions (2009) (219)
Quantitative atlas of blood-brain barrier transporters, receptors, and tight junction proteins in rats and common marmoset. (2013) (196)
Role of blood–brain barrier organic anion transporter 3 (OAT3) in the efflux of indoxyl sulfate, a uremic toxin: its involvement in neurotransmitter metabolite clearance from the brain (2002) (194)
Quantitative membrane protein expression at the blood-brain barrier of adult and younger cynomolgus monkeys. (2011) (194)
Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model. (2013) (183)
In Vivo and in Vitro Blood–Brain Barrier Transport of 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors (1994) (179)
A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood–brain barrier in ddY, FVB, and C57BL/6J mice (2013) (174)
Distinct cellular expressions of creatine synthetic enzyme GAMT and creatine kinases uCK‐Mi and CK‐B suggest a novel neuron–glial relationship for brain energy homeostasis (2004) (169)
The Blood–Brain Barrier Creatine Transporter is a Major Pathway for Supplying Creatine to the Brain (2002) (167)
New approaches to in vitro models of blood-brain barrier drug transport. (2003) (159)
Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein. (1993) (159)
A functional in vitro model of rat blood–brain barrier for molecular analysis of efflux transporters (2007) (158)
P-Glycoprotein mediates the efflux of quinidine across the blood-brain barrier. (1997) (153)
Rat Organic Anion Transporter 3 (rOAT3) is Responsible for Brain-to-Blood Efflux of Homovanillic Acid at the Abluminal Membrane of Brain Capillary Endothelial Cells (2003) (152)
Simultaneous absolute quantification of 11 cytochrome P450 isoforms in human liver microsomes by liquid chromatography tandem mass spectrometry with in silico target peptide selection. (2011) (151)
Involvement of the Pyrilamine Transporter, a Putative Organic Cation Transporter, in Blood-Brain Barrier Transport of Oxycodone (2008) (150)
Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat. (2001) (146)
Exogenous expression of claudin‐5 induces barrier properties in cultured rat brain capillary endothelial cells (2007) (144)
Blood—Brain Barrier Is Involved in the Efflux Transport of a Neuroactive Steroid, Dehydroepiandrosterone Sulfate, via Organic Anion Transporting Polypeptide 2 (2000) (141)
GAT2/BGT-1 as a System Responsible for the Transport of γ-Aminobutyric Acid at the Mouse Blood–Brain Barrier (2001) (137)
Absolute Quantification and Differential Expression of Drug Transporters, Cytochrome P450 Enzymes, and UDP-Glucuronosyltransferases in Cultured Primary Human Hepatocytes (2012) (136)
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney. (2002) (135)
Characterization of the organic cation transporter SLC22A16: a doxorubicin importer. (2005) (134)
mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting (2007) (133)
Physiologically Based Pharmacokinetic Model for β-Lactam Antibiotics I: Tissue Distribution and Elimanation Rates (1983) (133)
Distinct spatio‐temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain (2005) (133)
Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte‐derived soluble factor(s) (2004) (131)
Quantitative targeted absolute proteomics-based ADME research as a new path to drug discovery and development: methodology, advantages, strategy, and prospects. (2011) (127)
Efficient transfer of receptor-associated protein (RAP) across the blood-brain barrier (2004) (125)
SLCO4C1 transporter eliminates uremic toxins and attenuates hypertension and renal inflammation. (2009) (119)
Quantitative Proteomics of Transporter Expression in Brain Capillary Endothelial Cells Isolated from P-Glycoprotein (P-gp), Breast Cancer Resistance Protein (Bcrp), and P-gp/Bcrp Knockout Mice (2012) (115)
Efficient delivery of circulating poliovirus to the central nervous system independently of poliovirus receptor. (1997) (114)
H+ gradient-dependent and carrier-mediated transport of cefixime, a new cephalosporin antibiotic, across brush-border membrane vesicles from rat small intestine. (1987) (111)
Blood-Brain Barrier (BBB) Pharmacoproteomics: Reconstruction of In Vivo Brain Distribution of 11 P-Glycoprotein Substrates Based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice (2011) (110)
Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood–brain barrier function (2010) (110)
Regulation of taurine transport at the blood–brain barrier by tumor necrosis factor‐α, taurine and hypertonicity (2002) (109)
Functional characterization of the brain-to-blood efflux clearance of human amyloid-β peptide (1–40) across the rat blood–brain barrier (2006) (108)
Large‐scale multiplex absolute protein quantification of drug‐metabolizing enzymes and transporters in human intestine, liver, and kidney microsomes by SWATH‐MS: Comparison with MRM/SRM and HR‐MRM/PRM (2016) (108)
Transcellular Transport of Benzole Acid Across Caco-2 Cells by a pH-Dependent and Carrier-Mediated Transport Mechanism (2004) (106)
Insulin Facilitates the Hepatic Clearance of Plasma Amyloid β-Peptide (1–40) by Intracellular Translocation of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP-1) to the Plasma Membrane in Hepatocytes (2007) (104)
Aβ Immunotherapy: Intracerebral Sequestration of Aβ by an Anti-Aβ Monoclonal Antibody 266 with High Affinity to Soluble Aβ (2009) (104)
Transport mechanism of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors at the blood-brain barrier. (1993) (102)
In vivo evidence for carrier-mediated efflux transport of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine across the blood-brain barrier via a probenecid-sensitive transport system. (1997) (102)
Peripheral nerve pericytes modify the blood–nerve barrier function and tight junctional molecules through the secretion of various soluble factors (2011) (102)
The Low Density Lipoprotein Receptor-related Protein 1 Mediates Uptake of Amyloid β Peptides in an in Vitro Model of the Blood-Brain Barrier Cells* (2008) (101)
MCT1-Mediated Transport of L-Lactic Acid at the Inner Blood–Retinal Barrier: A Possible Route for Delivery of Monocarboxylic Acid Drugs to the Retina (2001) (99)
Peripheral Nerve pericytes originating from the blood–nerve barrier expresses tight junctional molecules and transporters as barrier‐forming cells (2008) (99)
In vitro models for the blood-brain barrier. (1998) (99)
Critical role of TXNIP in oxidative stress, DNA damage and retinal pericyte apoptosis under high glucose: implications for diabetic retinopathy. (2013) (98)
Depletion of Vitamin E Increases Amyloid β Accumulation by Decreasing Its Clearances from Brain and Blood in a Mouse Model of Alzheimer Disease* (2009) (97)
mRNA Expression and Transport Characterization of Conditionally Immortalized Rat Brain Capillary Endothelial Cell Lines; a New in vitro BBB Model for Drug Targeting (2000) (97)
Major Involvement of Low-Density Lipoprotein Receptor-Related Protein 1 in the Clearance of Plasma Free Amyloid β-Peptide by the Liver (2006) (95)
Organic anion transporter 3 is involved in the brain‐to‐blood efflux transport of thiopurine nucleobase analogs (2004) (95)
Restricted transport of 3'-azido-3'-deoxythymidine and dideoxynucleosides through the blood-brain barrier. (1988) (92)
L-type amino acid transporter 1-mediated L-leucine transport at the inner blood-retinal barrier. (2005) (90)
Expression and regulation of L‐cystine transporter, system xc−, in the newly developed rat retinal Müller cell line (TR‐MUL) (2003) (88)
Role of efflux transport across the blood-brain barrier and blood-cerebrospinal fluid barrier on the disposition of xenobiotics in the central nervous system☆ (1997) (88)
Efflux of a suppressive neurotransmitter, GABA, across the blood–brain barrier (2001) (88)
Conditionally immortalized cell lines as a new in vitro model for the study of barrier functions. (2001) (85)
Transport of monocarboxylic acids at the blood-brain barrier: studies with monolayers of primary cultured bovine brain capillary endothelial cells. (1991) (85)
Na(+)- and Cl(-)-dependent transport of taurine at the blood-brain barrier. (1995) (85)
Absorptive-mediated endocytosis of a dynorphin-like analgesic peptide, E-2078 into the blood-brain barrier. (1989) (84)
Brain Insulin Impairs Amyloid-β(1-40) Clearance from the Brain (2004) (84)
Vitamin C transport in oxidized form across the rat blood-retinal barrier. (2004) (83)
1α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier (2011) (83)
Diphenhydramine active uptake at the blood-brain barrier and its interaction with oxycodone in vitro and in vivo. (2011) (79)
Cerebral clearance of human amyloid‐β peptide (1–40) across the blood–brain barrier is reduced by self‐aggregation and formation of low‐density lipoprotein receptor‐related protein‐1 ligand complexes (2007) (77)
Quantitative expression of human drug transporter proteins in lung tissues: analysis of regional, gender, and interindividual differences by liquid chromatography-tandem mass spectrometry. (2013) (76)
Pharmacokinetic study on the mechanism of tissue distribution of doxorubicin: interorgan and interspecies variation of tissue-to-plasma partition coefficients in rats, rabbits, and guinea pigs. (1984) (76)
Mouse Reduced in Osteosclerosis Transporter Functions as an Organic Anion Transporter 3 and Is Localized at Abluminal Membrane of Blood-Brain Barrier (2004) (75)
Induction of Endoplasmic Reticulum Stress in Retinal Pericytes by Glucose Deprivation (2006) (75)
Blood‐Brain Barrier Produces Significant Efflux of L‐Aspartic Acid but Not D‐Aspartic Acid (1999) (74)
Localization of norepinephrine and serotonin transporter in mouse brain capillary endothelial cells (2002) (74)
Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) on Pharmacokinetics and Central Nervous System Penetration of Abacavir and Zidovudine in the Mouse (2008) (72)
Quantitative targeted absolute proteomics of rat blood–cerebrospinal fluid barrier transporters: comparison with a human specimen (2015) (72)
Identification of IGFBP2 and IGFBP3 As Compensatory Biomarkers for CA19-9 in Early-Stage Pancreatic Cancer Using a Combination of Antibody-Based and LC-MS/MS-Based Proteomics (2016) (71)
Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics (2018) (69)
ATA2 is predominantly expressed as system A at the blood-brain barrier and acts as brain-to-blood efflux transport for L-proline. (2002) (68)
ATP-Binding Cassette Transporter G2 Mediates the Efflux of Phototoxins on the Luminal Membrane of Retinal Capillary Endothelial Cells (2006) (68)
Roles of Inner Blood-Retinal Barrier Organic Anion Transporter 3 in the Vitreous/Retina-to-Blood Efflux Transport of p-Aminohippuric Acid, Benzylpenicillin, and 6-Mercaptopurine (2009) (67)
Efflux of taurocholic acid across the blood-brain barrier: interaction with cyclic peptides. (1998) (67)
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans. (2013) (67)
Enhancement of L-cystine transport activity and its relation to xCT gene induction at the blood-brain barrier by diethyl maleate treatment. (2002) (67)
Multichannel Liquid Chromatography–Tandem Mass Spectrometry Cocktail Method for Comprehensive Substrate Characterization of Multidrug Resistance-Associated Protein 4 Transporter (2007) (67)
Reliability and robustness of simultaneous absolute quantification of drug transporters, cytochrome P450 enzymes, and Udp-glucuronosyltransferases in human liver tissue by multiplexed MRM/selected reaction monitoring mode tandem mass spectrometry with nano-liquid chromatography. (2011) (66)
Selective brain to blood efflux transport of para-aminohippuric acid across the blood-brain barrier: in vivo evidence by use of the brain efflux index method. (1997) (64)
Major involvement of Na+‐dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells (2015) (63)
Function and regulation of taurine transport at the inner blood-retinal barrier. (2007) (63)
Physiologically based pharmacokinetic model for cefazolin in rabbits and its preliminary extrapolation to man. (1985) (63)
Quantitative Atlas of Cytochrome P450, UDP-Glucuronosyltransferase, and Transporter Proteins in Jejunum of Morbidly Obese Subjects. (2016) (62)
Physiologically based pharmacokinetic model for beta-lactam antibiotics I: Tissue distribution and elimination in rats. (1983) (61)
Internalization of basic fibroblast growth factor at the mouse blood–brain barrier involves perlecan, a heparan sulfate proteoglycan (2002) (61)
Characterization of the Amino Acid Transport of New Immortalized Choroid Plexus Epithelial Cell Lines: A Novel In Vitro System for Investigating Transport Functions at the Blood-Cerebrospinal Fluid Barrier (2004) (61)
In vitro study of the functional expression of organic anion transporting polypeptide 3 at rat choroid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood transport of estrone-3-sulfate. (2003) (60)
Coordinating Etk/Bmx activation and VEGF upregulation to promote cell survival and proliferation (2002) (60)
Carrier-mediated uptake of nicotinic acid by rat intestinal brush-border membrane vesicles and relation to monocarboxylic acid transport. (1990) (60)
Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro (2007) (59)
Blood‐to‐retina transport of creatine via creatine transporter (CRT) at the rat inner blood–retinal barrier (2004) (59)
Human Platelets Express Organic Anion-Transporting Peptide 2B1, an Uptake Transporter for Atorvastatin (2009) (58)
Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model (2013) (57)
24S‐hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical‐ and apoE isoform‐dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression (2007) (56)
Quantitative Determination of Luminal and Abluminal Membrane Distributions of Transporters in Porcine Brain Capillaries by Plasma Membrane Fractionation and Quantitative Targeted Proteomics. (2015) (56)
Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis (2018) (55)
Distributed model analysis of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine distribution in brain tissue and cerebrospinal fluid. (1997) (55)
Quantitative brain microdialysis study on the mechanism of quinolones distribution in the central nervous system. (1997) (55)
The l‐isomer‐selective transport of aspartic acid is mediated by ASCT2 at the blood–brain barrier (2003) (55)
Brain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier: An overview of biology and methodology (2011) (53)
Expression and possible role of creatine transporter in the brain and at the blood‐cerebrospinal fluid barrier as a transporting protein of guanidinoacetate, an endogenous convulsant (2008) (53)
Differential Contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in Vivo Renal Uptake of Uremic Toxins in Rats (2005) (52)
Induction of xCT gene expression and L-cystine transport activity by diethyl maleate at the inner blood-retinal barrier. (2002) (52)
Downregulation of retinal GLUT1 in diabetes by ubiquitinylation. (2004) (52)
Involvement of organic anion transporters in the efflux of uremic toxins across the blood–brain barrier (2006) (52)
Localization of organic anion transporting polypeptide 3 (oatp3) in mouse brain parenchymal and capillary endothelial cells (2004) (51)
An application of microdialysis to drug tissue distribution study: in vivo evidence for free-ligand hypothesis and tissue binding of beta-lactam antibiotics in interstitial fluids. (1992) (51)
Platelet‐derived growth factor‐BB (PDGF‐BB) induces differentiation of bone marrow endothelial progenitor cell‐derived cell line TR‐BME2 into mural cells, and changes the phenotype (2005) (51)
Transport mechanism of a new behaviorally highly potent adrenocorticotropic hormone (ACTH) analog, ebiratide, through the blood-brain barrier. (1991) (51)
β-Lactam antibiotics and transport via the dipeptide carrier system across the intestinal brush-border membrane (1987) (50)
Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics. (1997) (50)
Acidic drug transport in vivo through the blood-brain barrier. A role of the transport carrier for monocarboxylic acids. (1990) (49)
In vivo and in vitro evidence for a common carrier mediated transport of choline and basic drugs through the blood-brain barrier. (1990) (48)
Blood-Brain Barrier Pharmacoproteomics-Based Reconstruction of the In Vivo Brain Distribution of P-Glycoprotein Substrates in Cynomolgus Monkeys (2014) (48)
Brain insulin impairs amyloid-beta(1-40) clearance from the brain. (2004) (48)
Intestinal brush‐border transport of the oral cephalosporin antibiotic, cefdinir, mediated by dipeptide and monocarboxylic acid transport systems in rabbits (1993) (48)
Amyloid‐β peptide(1‐40) elimination from cerebrospinal fluid involves low‐density lipoprotein receptor‐related protein 1 at the blood‐cerebrospinal fluid barrier (2011) (47)
Muscle microdialysis as a model study to relate the drug concentration in tissue interstitial fluid and dialysate. (1991) (47)
Evidence for creatine biosynthesis in Müller glia (2005) (47)
Transport mechanism of an H1-antagonist at the blood-brain barrier: transport mechanism of mepyramine using the carotid injection technique. (1994) (47)
pH-dependent intestinal transport of monocarboxylic acids: carrier-mediated and H(+)-cotransport mechanism versus pH-partition hypothesis. (1990) (47)
In vivo evidence for carrier-mediated uptake of beta-lactam antibiotics through organic anion transport systems in rat kidney and liver. (1990) (46)
Carrier-mediated hepatic uptake of quinolone antibiotics in the rat. (1997) (46)
Structure-tissue distribution relationship based on physiological pharmacokinetics for NY-198, a new antimicrobial agent, and the related pyridonecarboxylic acids. (1988) (45)
The blood‐brain barrier fatty acid transport protein 1 (FATP1/SLC27A1) supplies docosahexaenoic acid to the brain, and insulin facilitates transport (2017) (45)
Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene (2000) (45)
Receptor-recycling model of clearance and distribution of insulin in the perfused mouse liver (1991) (45)
Blood-to-brain influx transport of nicotine at the rat blood–brain barrier: Involvement of a pyrilamine-sensitive organic cation transport process (2013) (44)
ATP-binding cassette transporter A1 (ABCA1) deficiency does not attenuate the brain-to-blood efflux transport of human amyloid-β peptide (1–40) at the blood–brain barrier (2008) (44)
Endothelial cells constituting blood-nerve barrier have highly specialized characteristics as barrier-forming cells. (2007) (44)
Proteome analysis of rat serum proteins adsorbed onto synthetic octacalcium phosphate crystals. (2011) (44)
Polarized glucose transporters and mRNA expression properties in newly developed rat syncytiotrophoblast cell lines, TR‐TBTs (2002) (43)
BMP signaling through BMPRIA in astrocytes is essential for proper cerebral angiogenesis and formation of the blood–brain-barrier (2008) (43)
The blood–brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters (2009) (43)
Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood–brain barrier (2008) (43)
Saturable uptake of cefixime, a new oral cephalosporin without an α‐amino group, by the rat intestine (1987) (42)
Cluster of Differentiation 46 Is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28). (2018) (42)
Recent advances in the brain-to-blood efflux transport across the blood-brain barrier. (2002) (41)
Functional characterization of rat plasma membrane monoamine transporter in the blood-brain and blood-cerebrospinal fluid barriers. (2011) (41)
Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor. (2007) (41)
A novel relationship between creatine transport at the blood-brain and blood-retinal barriers, creatine biosynthesis, and its use for brain and retinal energy homeostasis. (2007) (40)
Lack of brain‐to‐blood efflux transport activity of low‐density lipoprotein receptor‐related protein‐1 (LRP‐1) for amyloid‐β peptide(1–40) in mouse: involvement of an LRP‐1‐independent pathway (2010) (40)
Establishment of conditionally immortalized rat retinal pericyte cell lines (TR-rPCT) and their application in a co-culture system using retinal capillary endothelial cell line (TR-iBRB2). (2003) (39)
Drug Transporter Protein Quantification of Immortalized Human Lung Cell Lines Derived from Tracheobronchial Epithelial Cells (Calu-3 and BEAS2-B), Bronchiolar-Alveolar Cells (NCI-H292 and NCI-H441), and Alveolar Type II-like Cells (A549) by Liquid Chromatography-Tandem Mass Spectrometry. (2015) (37)
Dominant expression of androgen receptors and their functional regulation of organic anion transporter 3 in rat brain capillary endothelial cells; Comparison of gene expression between the blood–brain and ‐retinal barriers (2005) (37)
In Vivo Transport of a Dynorphin-like Analgesic Peptide, E-2078, Through the Blood–Brain Barrier: An Application of Brain Microdialysis (1991) (37)
Differential effect of plasma protein binding of bupivacaine on its in vivo transfer into the brain and salivary gland of rats. (1986) (37)
Brain‐to‐blood elimination of 24S‐hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood–brain barrier (2007) (37)
Comparative distribution of quinolone antibiotics in cerebrospinal fluid and brain in rats and dogs. (1996) (36)
LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line. (2017) (36)
Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks. (2015) (36)
Involvement of Multidrug Resistance-Associated Protein 4 in Efflux Transport of Prostaglandin E2 across Mouse Blood-Brain Barrier and Its Inhibition by Intravenous Administration of Cephalosporins (2010) (36)
Carrier-Mediated Transport of H1-Antagonist at the Blood-Brain Barrier: A Common Transport System of H1-Antagonists and Lipophilic Basic Drugs (1994) (36)
mRNA expression of the ATP-binding cassette transporter subfamily A (ABCA) in rat and human brain capillary endothelial cells. (2004) (36)
Carrier-Mediated Transport of H1-Antagonist at the Blood–Brain Barrier: Mepyramine Uptake into Bovine Brain Capillary Endothelial Cells in Primary Monolayer Cultures (1994) (36)
Nuclear binding as a determinant of tissue distribution of adriamycin, daunomycin, adriamycinol, daunorubicinol and actinomycin D. (1984) (36)
Contribution of Pannexin 1 and Connexin 43 Hemichannels to Extracellular Calcium–Dependent Transport Dynamics in Human Blood-Brain Barrier Endothelial Cells (2015) (35)
Modulation of retinal capillary endothelial cells by Müller glial cell-derived factors (2009) (35)
Cellular uptake mechanism for oligonucleotides: involvement of endocytosis in the uptake of phosphodiester oligonucleotides by a human colorectal adenocarcinoma cell line, HCT-15. (1996) (35)
In‐vivo Blood‐brain Barrier Transport of a Novel Adrenocorticotropic Hormone Analogue, Ebiratide, Demonstrated by Brain Microdialysis and Capillary Depletion Methods (1992) (35)
The blood‐cerebrospinal fluid barrier is a major pathway of cerebral creatinine clearance: involvement of transporter‐mediated process (2008) (34)
Differential binding of testosterone and estradiol to isoforms of sex hormone-binding globulin: selective alteration of estradiol binding in cirrhosis. (1988) (34)
Retinal‐specific ATP‐binding cassette transporter (ABCR/ABCA4) is expressed at the choroid plexus in rat brain (2005) (33)
Quantitative Targeted Proteomics of Pancreatic Cancer: Deoxycytidine Kinase Protein Level Correlates to Progression-Free Survival of Patients Receiving Gemcitabine Treatment. (2015) (33)
Altered expression of basement membrane-related molecules in rat brain pericyte, endothelial, and astrocyte cell lines after transforming growth factor-beta1 treatment. (2007) (33)
Quantitative targeted proteomics for understanding the blood–brain barrier: towards pharmacoproteomics (2014) (33)
Activation of carrier-mediated transport of L-cystine at the blood-brain and blood-retinal barriers in vivo. (2001) (33)
Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS (2014) (32)
Expression of ABC-type transport proteins in human platelets (2010) (32)
Brain-to-blood efflux transport of estrone-3-sulfate at the blood-brain barrier in rats. (2000) (32)
Beneficial Effects of Estrogen in a Mouse Model of Cerebrovascular Insufficiency (2009) (32)
Quantitative targeted absolute proteomics-based large-scale quantification of proline-hydroxylated α-fibrinogen in plasma for pancreatic cancer diagnosis. (2013) (32)
Attenuation of prostaglandin E2 elimination across the mouse blood-brain barrier in lipopolysaccharide-induced inflammation and additive inhibitory effect of cefmetazole (2011) (31)
Sodium and Chloride Ion‐Dependent Transport of β‐Alanine Across the Blood‐Brain Barrier (1996) (31)
Modulation and compensation of the mRNA expression of energy related transporters in the brain of glucose transporter 1-deficient mice. (2006) (31)
Blood–brain barrier transport of a novel µ1‐specific opioid peptide, H‐Tyr‐d‐Arg‐Phe‐β‐Ala‐OH (TAPA) (2003) (31)
Establishment and characterization of human peripheral nerve microvascular endothelial cell lines: a new in vitro blood-nerve barrier (BNB) model. (2012) (31)
Establishing a Method to Isolate Rat Brain Capillary Endothelial Cells by Magnetic Cell Sorting and Dominant mRNA Expression of Multidrug Resistance-associated Protein 1 and 4 in Highly Purified Rat Brain Capillary Endothelial Cells (2007) (31)
Quantification of Transporter and Receptor Proteins in Dog Brain Capillaries and Choroid Plexus: Relevance for the Distribution in Brain and CSF of Selected BCRP and P-gp Substrates. (2017) (31)
Mechanisms of intestinal absorption of the antibiotic, fosfomycin, in brush-border membrane vesicles in rabbits and humans. (1992) (30)
Newly developed rat brain pericyte cell line, TR-PCT1, responds to transforming growth factor-β1 and β-glycerophosphate (2002) (30)
Downregulation of GNA13-ERK network in prefrontal cortex of schizophrenia brain identified by combined focused and targeted quantitative proteomics. (2017) (30)
Functional expression of intestinal dipeptide/beta-lactam antibiotic transporter in Xenopus laevis oocytes. (1994) (30)
Donepezil, tacrine and α-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB) (2005) (30)
mRNA expression and amino acid transport characteristics of cultured human brain microvascular endothelial cells (hBME). (2002) (29)
Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells. (2003) (29)
From somatostatin to sandostatin: pharmacodynamics and pharmacokinetics. (1993) (28)
Characterization of immortalized choroid plexus epithelial cell lines for studies of transport processes across the blood-cerebrospinal fluid barrier (2010) (28)
Effect of Receptor Up-Regulation on Insulin Pharmacokinetics in Streptozotocin-Treated Diabetic Rats (1991) (28)
Uptake of benzylpenicillin, cefpiramide and cefazolin by freshly prepared rat hepatocytes. Evidence for a carrier-mediated transport system. (1986) (28)
A new in vitro model for blood-cerebrospinal fluid barrier transport studies: an immortalized choroid plexus epithelial cell line derived from the tsA58 SV40 large T-antigen gene transgenic rat. (2004) (27)
GSK-3β/CREB axis mediates IGF-1-induced ECM/adhesion molecule expression, cell cycle progression and monolayer permeability in retinal capillary endothelial cells: Implications for diabetic retinopathy. (2011) (27)
Reduction of L-type amino acid transporter 1 mRNA expression in brain capillaries in a mouse model of Parkinson's disease. (2010) (27)
Comparison of absolute protein abundances of transporters and receptors among blood-brain barriers at different cerebral regions and blood-spinal cord barrier in human and rat. (2020) (27)
Carrier-mediated hepatic uptake of the cationic cyclopeptide, octreotide, in rats. Comparison between in vivo and in vitro. (1997) (27)
Abundant Expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1, and xCT Transporters in Blood-Arachnoid Barrier of Pig and Polarized Localizations at CSF- and Blood-Facing Plasma Membranes (2019) (27)
Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases (2015) (27)
Effect of extracellular water volume on the distribution kinetics of beta-lactam antibiotics as a function of age. (1985) (26)
Evidence for a carrier-mediated transport system in the small intestine available for FK089, a new cephalosporin antibiotic without an amino group. (1986) (26)
Attenuation of Phosphorylation by Deoxycytidine Kinase is Key to Acquired Gemcitabine Resistance in a Pancreatic Cancer Cell Line: Targeted Proteomic and Metabolomic Analyses in PK9 Cells (2012) (26)
Acidic amino acid transport characteristics of a newly developed conditionally immortalized rat type 2 astrocyte cell line (TR-AST). (2001) (26)
Fluids and Barriers of the CNS: a new journal encompassing Cerebrospinal Fluid Research (2011) (26)
Stereospecificity of triiodothyronine transport into brain, liver, and salivary gland: role of carrier- and plasma protein-mediated transport. (1987) (26)
Involvement of insulin-degrading enzyme in insulin- and atrial natriuretic peptide-sensitive internalization of amyloid-β peptide in mouse brain capillary endothelial cells. (2013) (26)
Rat brain pericyte cell lines expressing β2‐adrenergic receptor, angiotensin II receptor type 1A, klotho, and CXCR4 mRNAs despite having endothelial cell markers (2003) (26)
Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system (2011) (25)
Dysfunction of choline transport system through blood-brain barrier in stroke-prone spontaneously hypertensive rats. (1990) (25)
Kinetic evidence for a common transport route of benzylpenicillin and probenecid by freshly prepared hepatocytes in rats. Influence of sodium ion, organic anions, amino acids and peptides on benzylpenicillin uptake. (1986) (25)
Pharmacoproteomics-Based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-Kindled Epilepsy, Spontaneous Epilepsy, and Phenytoin Treatment Models (2014) (25)
Increased JNK phosphorylation and oxidative stress in response to increased glucose flux through increased GLUT1 expression in rat retinal endothelial cells. (2005) (25)
Sodium and pH dependent carrier-mediated transport of antibiotic, fosfomycin, in the rat intestinal brush-border membrane. (1990) (24)
Validation of a P-Glycoprotein (P-gp) Humanized Mouse Model by Integrating Selective Absolute Quantification of Human MDR1, Mouse Mdr1a and Mdr1b Protein Expressions with In Vivo Functional Analysis for Blood-Brain Barrier Transport (2015) (24)
In‐vivo and In‐vitro Evidence of a Carrier‐mediated Efflux Transport System for Oestrone‐3‐sulphate across the Blood‐Cerebrospinal Fluid Barrier (2000) (24)
Participation of monocarboxylic anion and bicarbonate exchange system for the transport of acetic acid and monocarboxylic acid drugs in the small intestinal brush-border membrane vesicles. (1991) (24)
In vivo delivery of small interfering RNA targeting brain capillary endothelial cells. (2006) (24)
Drug Clearance from Cerebrospinal Fluid Mediated by Organic Anion Transporters 1 (Slc22a6) and 3 (Slc22a8) at Arachnoid Membrane of Rats. (2018) (24)
High Expression of UGT1A1/1A6 in Monkey Small Intestine: Comparison of Protein Expression Levels of Cytochromes P450, UDP-Glucuronosyltransferases, and Transporters in Small Intestine of Cynomolgus Monkey and Human. (2018) (24)
In vivo evidence for brain-to-blood efflux transport of valproic acid across the blood-brain barrier. (2002) (24)
In vivo and in vitro evidence of blood-brain barrier transport of a novel cationic arginine-vasopressin fragment 4-9 analog. (1999) (23)
Identification of Transporters Associated with Etoposide Sensitivity of Stomach Cancer Cell Lines and Methotrexate Sensitivity of Breast Cancer Cell Lines by Quantitative Targeted Absolute Proteomics (2013) (23)
Is P‐glycoprotein Involved in Amyloid‐β Elimination Across the Blood–Brain Barrier in Alzheimer's Disease? (2010) (23)
Molecular-weight-dependent, anionic-substrate-preferential transport of β-lactam antibiotics via multidrug resistance-associated protein 4. (2011) (23)
From somatostatin to Sandostatin: pharmacodynamics and pharmacokinetics. (1992) (23)
Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs. (2017) (23)
Establishment and characterization of conditionally immortalized endothelial cell lines from the thoracic duct and inferior vena cava of tsA58/EGFP double-transgenic rats (2006) (23)
Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect. (2010) (22)
A carrier‐mediated transport system for benzylpenicillin in isolated hepatocytes (1985) (22)
Physiological pharmacokinetics of Mactam antibiotics: penicillin V distribution and elimination after intravenous administration in rats (1979) (22)
Characterization of the Mechanism of Zidovudine Uptake by Rat Conditionally Immortalized Syncytiotrophoblast Cell Line TR-TBT (2008) (22)
Actin filament‐associated protein 1 (AFAP‐1) is a key mediator in inflammatory signaling‐induced rapid attenuation of intrinsic P‐gp function in human brain capillary endothelial cells (2017) (21)
Absorptive-Mediated Endocytosis of an Adrenocorticotropic Hormone (ACTH) Analogue, Ebiratide, into the Blood–Brain Barrier: Studies with Monolayers of Primary Cultured Bovine Brain Capillary Endothelial Cells (1992) (21)
Drug delivery to the brain utilizing blood-brain barrier transport systems (1994) (21)
Effects of Arginine-Vasopressin Fragment 4–9 on Rodent Cholinergic Systems (1999) (21)
Vascular EndotheliumSelective Gene Induction by Tie2 Promoter/Enhancer in the Brain and Retina of a Transgenic Rat (2005) (20)
Inner Blood-Retinal Barrier Dominantly Expresses Breast Cancer Resistance Protein: Comparative Quantitative Targeted Absolute Proteomics Study of CNS Barriers in Pig. (2017) (20)
Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood–brain barrier (2020) (20)
Liver Zonation Index of Drug Transporter and Metabolizing Enzyme Protein Expressions in Mouse Liver Acinus (2018) (19)
ATP-Binding Cassette Transporter A Subfamily 8 Is a Sinusoidal Efflux Transporter for Cholesterol and Taurocholate in Mouse and Human Liver. (2018) (19)
In vivo and in vitro evidence for nonrestricted transport of 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein tetraacetoxymethyl ester at the blood-brain barrier. (1997) (19)
Establishment of Bone Marrow-Derived Endothelial Cell Lines From ts-SV40 T-antigen Gene Transgenic Rats (2001) (19)
Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer's Disease. (2018) (19)
Atrial Natriuretic Peptide is Eliminated from the Brain by Natriuretic Peptide Receptor-C-Mediated Brain-to-Blood Efflux Transport at the Blood—Brain Barrier (2011) (18)
Oral Morphine Pharmacokinetic in Obesity: The Role of P-Glycoprotein, MRP2, MRP3, UGT2B7, and CYP3A4 Jejunal Contents and Obesity-Associated Biomarkers. (2016) (18)
The HMG-CoA reductase inhibitor pravastatin stimulates insulin secretion through organic anion transporter polypeptides. (2010) (18)
Pharmacological significance of prostaglandin E2 and D2 transport at the brain barriers. (2014) (18)
PKC/MAPK signaling suppression by retinal pericyte conditioned medium prevents retinal endothelial cell proliferation (2005) (18)
Developmental changes in transporter and receptor protein expression levels at the rat blood-brain barrier based on quantitative targeted absolute proteomics. (2019) (18)
Quantitative Targeted Absolute Proteomics for 28 Transporters in Brush-Border and Basolateral Membrane Fractions of Rat Kidney. (2016) (17)
Physiological pharmacokinetics of a new muscle-relaxant, inaperisone, combined with its pharmacological effect on blood flow rate. (1990) (17)
Enhancement of Zidovudine Uptake by Dehydroepiandrosterone Sulfate in Rat Syncytiotrophoblast Cell Line TR-TBT 18d-1 (2008) (17)
Contributions of Degradation and Brain-to-blood Elimination Across the Blood—Brain Barrier to Cerebral Clearance of Human Amyloid-β Peptide(1-40) in Mouse Brain (2013) (17)
In‐vitro Evidence for Carrier‐mediated Uptake of Acidic Drugs by Isolated Bovine Brain Capillaries (1991) (17)
Differences in the hepatobiliary transport of two quinolone antibiotics, grepafloxacin and lomefloxacin, in the rat (1999) (17)
Preface: Targeted Drug Delivery to the Brain (Blood-Brain Barrier, Efflux, Endothelium, Biological Transport) (2000) (17)
Polyol formation in cell lines of rat retinal capillary pericytes and endothelial cells (TR-rPCT and TR-iBRB). (2009) (17)
Brain‐to‐blood active transport of β‐alanine across the blood–brain barrier (1997) (16)
Establishment and validation of highly accurate formalin-fixed paraffin-embedded quantitative proteomics by heat-compatible pressure cycling technology using phase-transfer surfactant and SWATH-MS (2020) (16)
Serum protein binding of lomefloxacin, a new antimicrobial agent, and its related quinolones. (1989) (16)
Receptor-mediated endocytosis of A14-125I-insulin by the nonfiltering perfused rat kidney. (1991) (16)
Mechanism of the tissue distribution and biliary excretion of the cyclic peptide octreotide. (1996) (16)
Recent Progress in Blood–Brain Barrier and Blood–CSF Barrier Transport Research: Pharmaceutical Relevance for Drug Delivery to the Brain (2014) (16)
Evidence for the existence of a common transport system of beta-lactam antibiotics in isolated rat hepatocytes. (1985) (16)
Age-related change in tissue-to-plasma partition coefficient of cefazolin for noneliminating organs in the rat. (1989) (16)
Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood–brain barrier transporters (2020) (15)
Interaction of doxorubicin with nuclei isolated from rat liver and kidney. (1984) (15)
Selective gene silencing of rat ATP‐binding cassette G2 transporter in an in vitro blood–brain barrier model by short interfering RNA (2005) (15)
Fgf2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus epithelial cell behaviour (2008) (15)
Blood-Brain Barrier Permeability of Novel [d-Arg2]Dermorphin (1-4) Analogs: Transport Property Is Related to the Slow Onset of Antinociceptive Activity in the Central Nervous System (2004) (15)
Gene therapy for a mouse model of glucose transporter-1 deficiency syndrome (2017) (14)
Gene therapy for Glut1‐deficient mouse using an adeno‐associated virus vector with the human intrinsic GLUT1 promoter (2018) (14)
Quantitative Targeted Absolute Proteomics of Transporters and Pharmacoproteomics-Based Reconstruction of P-Glycoprotein Function in Mouse Small Intestine. (2016) (14)
Correlation of Organic Cation/Carnitine Transporter 1 and Multidrug Resistance-Associated Protein 1 Transport Activities With Protein Expression Levels in Primary Cultured Human Tracheal, Bronchial, and Alveolar Epithelial Cells. (2016) (14)
Relationship between lipophilicity and binding affinity with human serum albumin for penicillin and cephem antibiotics. (1992) (14)
Organic Anion-Transporting Polypeptide 1a4 (Oatp1a4/Slco1a4) at the Blood-Arachnoid Barrier is the Major Pathway of Sulforhodamine-101 Clearance from Cerebrospinal Fluid of Rats. (2019) (14)
Evaluation of Organic Anion Transporter 1A2-knock-in Mice as a Model of Human Blood-brain Barrier (2018) (14)
Establishment and characterization of spinal cord microvascular endothelial cell lines (2013) (13)
Newly developed rat brain pericyte cell line, TR-PCT1, responds to transforming growth factor-beta1 and beta-glycerophosphate. (2002) (12)
Gelsolin inhibits malignant phenotype of glioblastoma and is regulated by miR‐654‐5p and miR‐450b‐5p (2020) (12)
Increased Expression of Renal Drug Transporters in a Mouse Model of Familial Alzheimer's Disease. (2019) (12)
Kinetic analysis of the disposition of MRK16, an anti-P-glycoprotein monoclonal antibody, in tumors: comparison between in vitro and in vivo disposition. (1997) (12)
Recurrent anaplastic meningioma treated by sunitinib based on results from quantitative proteomics (2012) (12)
[Molecular mechanisms of drug influx and efflux transport at the blood-brain barrier]. (2003) (12)
Amyloid beta25‐35 impairs docosahexaenoic acid efflux by down‐regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells (2019) (12)
Change in hepatic handling of hepatocyte growth factor during liver regeneration in rats. (1995) (11)
Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters. (2019) (11)
Transport of the new quinolone antibacterial agents of lomefloxacin and ofloxacin by rat erythrocytes, and its relation to the nicotinic acid transport system. (1991) (11)
Age-related change of cefazolin binding to rat serum proteins and its relation to the molar ratio of free fatty acid to serum albumin. (1986) (11)
Quantification of ENT1 and ENT2 Proteins at the Placental Barrier and Contribution of These Transporters to Ribavirin Uptake. (2019) (11)
Uptake of drugs and expression of P-glycoprotein in the rat 9L glioma (2004) (11)
Epidermal growth factor targeting of bacteriophage to the choroid plexus for gene delivery to the central nervous system via cerebrospinal fluid (2010) (11)
Inner blood-retinal barrier mediates l-isomer-predominant transport of serine. (2011) (11)
Polarized hemichannel opening of pannexin 1/connexin 43 contributes to dysregulation of transport function in blood-brain barrier endothelial cells (2019) (11)
Characterization of the Transport Properties of a Quinolone Antibiotic, Fleroxacin, in Rat Choroid Plexus (1996) (11)
Regulation of extracellular-superoxide dismutase in rat retina pericytes (2010) (10)
Brain Efflux Index Method (2003) (10)
Augmented Expression of the Tight Junction Protein Occludin in Brain Endothelial Cell Line TR-BBB by Rat Angiopoietin-1 Expressed in Baculovirus-Infected Sf Plus Insect Cells (2002) (10)
All‐trans retinoic acid enhances gemcitabine cytotoxicity in human pancreatic cancer cell line AsPC‐1 by up‐regulating protein expression of deoxycytidine kinase (2017) (10)
Expression of the Na+ dependent uridine transport system of rabbit small intestine: studies with mRNA-injected Xenopus laevis oocytes. (1993) (10)
Identification and Validation of Combination Plasma Biomarker of Afamin, Fibronectin and Sex Hormone-Binding Globulin to Predict Pre-eclampsia. (2021) (10)
Introduction to the Blood–Brain Barrier: Development of Brain Efflux Index (BEI) method and its application to the blood–brain barrier efflux transport study (1998) (10)
Specific binding and clearance of [3H]dynorphin (1–13) in the perfused rat lung: an application of the multiple‐indicator dilution method (1990) (10)
Transporter mRNA expression in a conditionally immortalized rat small intestine epithelial cell line (TR-SIE). (2004) (9)
Retinal selectivity of gene expression in rat retinal versus brain capillary endothelial cell lines by differential display analysis. (2004) (9)
MK2461, a Multitargeted Kinase Inhibitor, Suppresses the Progression of Pancreatic Cancer by Disrupting the Interaction Between Pancreatic Cancer Cells and Stellate Cells (2017) (9)
Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood-Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters, Receptors or Tight Junction-Related Protein. (2019) (9)
Activation of Annexin A2 signaling at the blood–brain barrier in a mouse model of multiple sclerosis (2022) (9)
Differential binding of thyroxine and triiodothyronine to acidic isoforms of thyroid hormone binding globulin in human serum. (1988) (9)
Cell density-dependent mitogenic effect and -independent cellular handling of epidermal growth factor in primary cultured rat hepatocytes. (1997) (9)
Brain and heart specific alteration of methamphetamine (MAP) distribution in MAP-sensitized rat. (2003) (9)
INTESTINAL UPTAKE OF β-LACTAM ANTIBIOTICS WITHOUT AN α-AMINO GROUP AND ITS RELATIONSHIP TO DIPEPTIDE TRANSPORT (1987) (8)
Brain efflux index method. Characterization of efflux transport across the blood-brain barrier. (2003) (8)
Carbenicillin Prodrugs: Stability Kinetics of α-phenyl and α-indanyl Esters in Aqueous Solution (1979) (8)
Abnormal N-Glycosylation of a Novel Missense Creatine Transporter Mutant, G561R, Associated with Cerebral Creatine Deficiency Syndromes Alters Transporter Activity and Localization. (2017) (8)
Global and Targeted Proteomics of Prostate Cancer Cell Secretome: Combination of 2-Dimensional Image-Converted Analysis of Liquid Chromatography and Mass Spectrometry and In Silico Selection Selected Reaction Monitoring Analysis. (2016) (7)
Application of Quantitative Targeted Absolute Proteomics to Profile Protein Expression Changes of Hepatic Transporters and Metabolizing Enzymes During Cholic Acid-Promoted Liver Regeneration. (2017) (7)
Hepatic Uptake of Octreotide, a Long-Acting Somatostatin Analogue, via a Bile Acid Transport System (2004) (7)
Carbenicillin prodrugs: kinetics of intestinal absorption competing degradation of the alpha-esters of carbenicillin and prediction of prodrug absorbability from quantitative structure-absorption rate relationship. (1982) (7)
An Atlas of the Quantitative Protein Expression of Anti-Epileptic-Drug Transporters, Metabolizing Enzymes and Tight Junctions at the Blood–Brain Barrier in Epileptic Patients (2021) (7)
A novel stromal cell-dependent B lymphoid stem-like cell line that induces immunoglobulin gene rearrangement. (1999) (7)
The Multipotential of Leucine-Rich α-2 Glycoprotein 1 as a Clinicopathological Biomarker of Glioblastoma. (2020) (7)
Kinetics of Quinolone Antibiotics in Rats: Efflux from Cerebrospinal Fluid to the Circulation (1996) (7)
Contribution of Parenchymal and Non-Parenchymal Liver Cells to the Clearance of Hepatocyte Growth Factor From the Circulation in Rats (1995) (7)
Theoretical consideration of drug distribution kinetics in a noneliminating organ: Comparison between a “homogeneous (well-stirred)” model and “nonhomogeneous (tube)” model (1985) (6)
Comparative pharmacokinetics of cefazolin in awake and urethane-anesthetized rats. (1985) (6)
Gene expression of A6-like subgroup of ATP-binding cassette transporters in mouse brain parenchyma and microvessels (2018) (6)
Pharmacoproteomics of Brain Barrier Transporters and Substrate Design for the Brain Targeted Drug Delivery (2022) (6)
Blood-brain barrier transport of a novel micro 1-specific opioid peptide, H-Tyr-D-Arg-Phe-beta-Ala-OH (TAPA). (2003) (6)
Brain-to-blood active transport of beta-alanine across the blood-brain barrier. (1997) (6)
Targeted proteomics-based quantitative protein atlas of pannexin and connexin subtypes in mouse and human tissues and cancer cell lines. (2020) (6)
Human platelets express OATP 2 B 1 , an uptake transporter for atorvastatin (2009) (6)
Blood–Brain Barrier (BBB) Pharmacoproteomics: A New Research Field Opened Up by Quantitative Targeted Absolute Proteomics (QTAP) (2014) (5)
Spleen lymphocyte kinetics in mice under normal and inflammatory conditions: an application of the transgenic mouse expressing beta-galactosidase (ROSA 26). (2002) (5)
Cell-Type-Specific Spatiotemporal Expression of Creatine Biosynthetic Enzyme S-adenosylmethionine:guanidinoacetate N-methyltransferase in Developing Mouse Brain (2018) (5)
Selective analysis of mutual displacement effects at the primary binding sites of phenoxymethylpenicillin and cephalothin bindings to human serum albumin. (1992) (5)
Downregulation of retinal GLUT 1 in diabetes by ubiquitinylation (2004) (4)
Brain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier: An overview of biology and methodology (2005) (4)
Beta-lactam antibiotics and transport via the dipeptide carrier system across the intestinal brush-border membrane. (1987) (4)
Binding mechanism and structure-binding relationship of β-lactam amtibiotics to humans antibiotics to human serum albumin (1986) (3)
Specific binding of beta-endorphin to the isolated renal basolateral membranes in vitro. (1990) (3)
Quantitative expression of ADME proteins at the blood-brain barrier (2017) (3)
Blood-Brain Barrier Permeability of Novel [ D-Arg 2 ] Dermorphin ( 1-4 ) Analogs : Transport Property Is Related to the Slow Onset of Antinociceptive Activity in the Central Nervous System (2004) (3)
Determination of Intrinsic Creatine Transporter (Slc6a8) Activity and Creatine Transport Function of Leukocytes in Rats. (2020) (3)
Modulation of the tumor disposition of vinca alkaloids by PSC 833 in vitro and in vivo. (1998) (3)
Identification of Blood-Brain Barrier-Permeable Proteins Derived from a Peripheral Organ: In Vivo and in Vitro Evidence of Blood-to-Brain Transport of Creatine Kinase. (2018) (3)
Scrambled Internal Standard Method for High-Throughput Protein Quantification by Matrix-Assisted Laser Desorption Ionization Tandem Mass Spectrometry. (2017) (3)
[Multi-disciplinary research approaches on the brain barrier transport system, a dynamic interface]. (2013) (2)
Corrigendum to “Proteome analysis of rat serum proteins adsorbed onto synthetic octacalcium phosphate crystals” [Anal. Biochem. 418 (2011) 276–285] (2012) (2)
Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood–Brain Barrier (2022) (2)
A case of sustained hypoglycemia induced by taking glibenclamide and warfarin (2003) (2)
Degradation kinetics of (+/-)-4'-ethyl-2-methyl-3-(1-pyrrolidinyl)propiophenone hydrochloride (HY-770) and structure-stability relationship among its analogues in aqueous solution. (1989) (2)
The Efflux Transport of Dehydroepiandrosterone Sulfate at the Blood-Brain Barrier (2000) (2)
Quantitative Targeted Absolute Proteomics for Better Characterization of an In Vitro Human Blood–Brain Barrier Model Derived from Hematopoietic Stem Cells (2022) (2)
MECHANISM OF CELLULAR UPTAKE OF ANTISENSE DNA (1994) (2)
USEFULNESS AND LIMITATION OF THE MICRODIALYSIS FIBER IMPLANTATION TECHNIQUE FOR THE DETERMINATION OF THE CONCENTRATION IN THE TISSUE INTERSTITIAL FLUID (1991) (2)
[Studies on the mechanism of drug distribution in tissues]. (1992) (2)
A human blood–arachnoid barrier atlas of transporters, receptors, enzymes, and tight junction and marker proteins: Comparison with dog and pig in absolute abundance (2022) (2)
JPET #184200 1 Blood-Brain Barrier (BBB) Pharmacoproteomics (PPx): Reconstruction of In Vivo Brain Distribution of 11 P-glycoprotein Substrates based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice (2011) (2)
QUANTITATIVE EVIDENCE FOR INTERSPECIES DIFFERENCE IN TISSUE DISTRIBUTION MECHANISM OF ADRIAMYCIN (1982) (1)
Distinct transport properties of human pannexin 1 and connexin 32 hemichannels. (2019) (1)
Downregulation of retinal GLUT1 in diabetes by the ubiquitin proteasome pathway (2004) (1)
Pharmacokinetics, Pharmacodynamics and Drug Transport and Metabolism Correlation of Organic Cation/Carnitine Transporter 1 and Multidrug Resistance-Associated Protein 1 Transport Activities With Protein Expression Levels in Primary Cultured Human Tracheal, Bronchial, and Alveolar Epithelial Cells (2016) (1)
A study protocol for quantitative targeted absolute proteomics (QTAP) by LC-MS/MS: application for inter-strain differences in protein expression levels of transporters, receptors, claudin-5, and marker proteins at the blood–brain barrier in ddY, FVB, and C57BL/6J mice (2013) (1)
Leukocyte Adhesion and Blood Retinal Barrier (BRB) Breakdown in Diabetic Retinopathy (DR): Role of Nitric Oxide (NO) (2005) (1)
Organ Variation in Tissue to Plasma Partition Coefficients of Adriamycin, Daunomycin and Actinomycin-D: Correlation to Tissue DNA Concentrations (1984) (1)
Overexpression of GLUT1 and Increased Glucose Transport Leads to Apoptosis in Retinal Endothelial Cells (2002) (1)
BINDING MECHANISM AND STRUCTURE-BINDING RELATIONSHIP OF β-LACTAM ANTIBIOTICS TO HUMAN SERUM ALBUMIN (1986) (1)
Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs (2022) (1)
Theoretical Study on the ATP Hydrolysis Mechanism of HisP Protein, the ATP-Binding Subunit of ABC Transporter (2007) (1)
Cerebral clearance of human amyloid-β peptide (1–40) across the blood-brain barrier is reduced by complex formation of activated α2-macroglobulin (2007) (1)
TRANSPORT OF β-LACTAM ANTIBIOTICS VIA THE DIPEPTIDE CARRIER SYSTEM ACROSS INTESTINAL BRUSH-BORDER MEMBRANE (1987) (1)
Subject Index, Vol. 54, Supplement 1, 1993 (1993) (0)
TRANSPORTS OF EXCITATORY AND INHIBITORY NEUROTRANSMITTERS ACROSS THE BLOOD-BRAIN BARRIER (2000) (0)
MPC-06 LRG1 HAS MULTIPLE POTENTIAL FOR CLINICOPATHOLOGICAL BIOMARKER OF GLIOBLASTOMA (2019) (0)
Abstract 2705: Quantitative targeted proteomics in pancreatic cancer: Combinations of enzyme and transporter protein expression are novel indicators for gemcitabine sensitivity (2010) (0)
Hexosamine Induction of Thioredoxin-Interacting Protein Expression Mediates Oxidative Stress and Inflammatory Response in Retinal Endothelial Cells: Implications of Diabetic Retinopathy (2008) (0)
The Difference of Blood-Brain Barrier Transport and Concentration in Brain Interstitial Fluid of Choline in SHRSP and WKY (1990) (0)
Transport of Basic Peptides at the Blood–Brain Barrier (2006) (0)
Kinetic analysis of the transport of the quinolone antibiotics across the blood-brain barrier and blood-CSF barrier (1993) (0)
A Novel Drug Delivery System of Hepatocyte Growth Factor (HGF): Utilization of Heparin-HGF Complex (1996) (0)
Evidence for Creatine Biosynthesis in M (2005) (0)
Title Targeting choroid plexus epithelia and ventricular ependyma for drug delivery to the central nervous system (2011) (0)
Increased JNK-interacting Protein 1 (JIP-1) and Oxidative Stress in Response to GLUT1 Overexpression in Rat Retinal Endothelial Cells (2003) (0)
P4-069 Modeling amyloid β-peptide transport across the blood-brain barrier in TR-BBB cells (2006) (0)
Pharmacokinetic simulator with three-dimensional graphical models: Sociotechnological interface of pharmacokinetics for medical personnel, patients, and medicinal chemists (2005) (0)
The specialized properties of endothelial cells constituting blood-nerve barrier (2007) (0)
Bcrp does not influence transport of nitrofurantoin across the blood-brain barrier at different ages (2009) (0)
Analysis of Drug Distribution Mechanism in Tissues (1992) (0)
AGE-RELATED CHANGES IN DISTRIBUTION VOLUME OF β-LACTAM ANTIBIOTICS (1985) (0)
Molecular characteristics of Aβ(1-40) peptide efflux transport across the blood-brain barrier (2005) (0)
THEORITECAL INVESTIGATION OF THE INTERACTION OF THEOPHYLLINE WITH THE HEME (2004) (0)
Carbenicillin prodrugs: stability kinetics of alpha-phenyl and alpha-indanyl esters in aqueous solution. (1979) (0)
■ Graduate Schools / Undergraduate Schools (2007) (0)
Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases (2014) (0)
[Development of Novel Methodology and Its Application for Clarifying the Transport Function of the Blood-brain Barrier]. (2021) (0)
ABSOLUTE EXPRESSION OF CYP, UGT AND TRANSPORTER PROTEINS IN CULTURED PRIMARY HUMAN HEPATOCYTES (2010) (0)
ANTIBODY-FREE QUANTIFICATION METHOD FOR AMYLOID BETA-PEPTIDES BY UPLC-MS/MS (2008) (0)
mRNA expression profile of claudin subtypes in mouse blood–brain barrier (2007) (0)
Quantitative targeted absolute proteomics (QTAP)-based rational research on the human blood-brain barrier transport (2013) (0)
Brain-to-blood efflux transport of endogenous compounds and its analogue drug at the blood-brain barrier (2008) (0)
Shift to the quantitative transporter research by utilizing mass-spectrometry (2007) (0)
Physiological pharmacokinetics and membrane transport for drug delivery research (2005) (0)
Rat retinal endothelial cell dysfunction induced by hyperglycemia and oxidative stress: additive effects? (2004) (0)
Blood‐Brain Barrier Transport of Ebiratide and Its Uptake by Cerebral Neuronal Cells (1993) (0)
Identification and Initial Characterization of Differentially Expressed Genes in Rat Retinal Endothelial Cells With Glucose Transporter 1 (GLUT1) Overexpression (2002) (0)
Kinetic analysis of the distribution of quinolone antibiotics in the central nervous system: Role of active efflux transport from the brain (1996) (0)
A phase I study of combination of panitumumab and bevacizumab in KRAS wild-type colorectal cancer patients who were previously treated with fluoropyrimidine, oxaliplatin, irinotecan, and bevacizumab. (2016) (0)
Perspectives on a pharmacokinetics legend: C versus T (contributions over time). (2013) (0)
Effect of disease state on blood-brain barrier transport of drugs mediated by endogenous transport systems (1990) (0)
Cell-Type-Specific Spatiotemporal Expression of Creatine Biosynthetic Enzyme S-adenosylmethionine:guanidinoacetate N-methyltransferase in Developing Mouse Brain (2017) (0)
Glucose Imbalance Induces the Unfolded Protein Response (UPR) in Rat Retinal Capillary Pericyte and Endothelial Cells (2006) (0)
Method for the production of choroid plexus immortalized cell lines (1999) (0)
Correction to Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer's Disease. (2021) (0)
Related articles (2015) (0)
[Molecular Mechanism Underlying the Function and Disintegration of the Central Nerve System Barrier Unraveled by Proteo-typing of Membrane Proteins]. (2021) (0)
Essential Role of GLUT1 in the Inner Blood-retinal Barrier Transport of Vitamin C (2003) (0)
Phase-3 Detoxification in the Liver: Biliary Excretion of small molecules and peptides by primary active transport mechanisms (1995) (0)
Development of quantitative analysis of drug transporter protein using LC-MS/MS (2006) (0)
Method for identifying amyloid beta bond protein (2003) (0)
Involvement of oatp2 in the efflux transport of 24S-hydroxycholesterol at the rat blood-brain barrier (2005) (0)
Kinetic analysis of the mechanism for disposition of hepatocyte growth factor in rats: Contribution of receptor-mediated endocytosis and non-specific uptake mechanism (1993) (0)
Hypoglycemia Induces Endoplasmic Reticulum (ER) Stress in Retinal Capillary Pericytes and Endothelial Cells (2007) (0)
POLYCATIONIC TRANSCYTOSIS OF DYNORPHIN-LIKE ANALGESIC PEPTIDE THROUGH BRAIN CAPILLARIES (1989) (0)
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs (2023) (0)
PHYSIOLOGICAL PHARMACOKINETICS OF BIOLOGICALLY ACTIVE PEPTIDES : EFFECTS OF RECEPTOR BINDING, RECEPTOR-MEDIATED ENDOCYTOSIS, AND RECEPTOR RECYCLING ON INSULIN DISPOSITION (1991) (0)
Immortal cell line vascular aventitiale (2001) (0)
Reconstitution of the blood-retinal barrier and blood-brain barrier, and its application for drug delivery study. (2001) (0)
Physiological pharmacokinetics combined with its pharmacological effect on blood flow rate an example of a new muscle relaxant hy 770 (1990) (0)
Polyol Formation in Rat Retinal Capillary Pericyte and Endothelial Cells (2006) (0)
TRANSCELLULAR TRANSPORT MECHANISM OF β-LACTAM ANTIBIOTICS AND ITS INTERORGAN RELATIONSHIP AMONG SMALL INTESTINE, KIDNEY AND LIVER (1989) (0)
New in Vitro model for the brain drug delivery research : Conditionally immortalized cell lines as novel models of the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB) (2003) (0)
CS-25MOLECULAR SUBCLASSIFICATION OF GLIOBLASTOMA BASED ON THE ABSOLUTE QUANTITATIVE PROTEOMICS (2014) (0)
Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis (2018) (0)
Functional and Molecular Characterization of Taurine Transporter, TAUT, at the Inner Blood-retinal Barrier (2002) (0)
Funcional expression of sterol ABC transporters and their regulation by LXR at the blood-cerebrospinal fluid barrier (2005) (0)
Molecular mechanism and regulation of hepatic clearance of Amyloid β-peptide (2006) (0)
S5.1 - Proteomics based studies of disease effects on the brain barrier transporters (2020) (0)
BLOOD-BRAIN BARRIER TRANSPORT AND DRUG TARGETING TO THE BRAIN (2002) (0)
FUNCTIONAL ANALYSIS OF THE BLOOD BRAIN BARRIER USING CONDITIONALLY IMMORTALIZED CELL LINES (2001) (0)
Confirmation of Carrier-Mediated Intestinal Transport of β-Lactam Antiboitics by Using Gene Expression in Xenopus laevis Oocytes (1993) (0)
Microsoft Word-27166710-file00 (2009) (0)
Molecular characteristics of Aβ(1-40) efflux across the blood-cerebrospinal fluid barrier (2006) (0)
transport for drug delivery research (2005) (0)
ELUCIDATION OF INTESTINAL ABSORPTION MECHANISMS BY USING XENOPUS LAEVIS OOCYTES (1992) (0)
Characterization of proteome profile data of chemicals based on data-independent acquisition MS with SWATH method (2023) (0)
INVESTIGATION OF THE INHIBITORY EFFECTS OF VARIOUS THERAPEUTIC DRUGS ON OATP1B3-MEDIATED UPTAKE OF FEXOFENADINE (2006) (0)
Transport Mechanism of Basic Fibroblast Growth Factor through the Blood-Brain Barrier (2000) (0)
Transport Characteristics and Substrate Specificity in Rat Inner Blood-Retinal Barrier Cell Line (TR-iBRB) (1999) (0)
Retinal Pericyte–Secreted Protein: Tropomyosin Plays a Role in Suppressing Retinal Endothelial Cell Growth (2006) (0)
Functional expression of a proton-coupled organic cation (H+/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model (2013) (0)
BLOOD-BRAIN BARRIER EFFLUX TRANSPORTERS : NEW CONCEPTS OF BARRIER FUNCTION (2000) (0)
Identification of serum proteins accumulated onto octacalcium phosphate in vitro (2011) (0)
CARRIER-MEDIATED TRANSPORT MECHANISM OF β-LACTAM ANTIBIOTICS IN ISOLATED HEPATOCYTES (1984) (0)
CRT as a system responsible for the transport of creatine at the inner blood-retinal barrier (2004) (0)
cDNA cloning and expression of novel organic ion transporter (2001) (0)
Establishment and validation of highly accurate formalin-fixed paraffin-embedded quantitative proteomics by heat-compatible pressure cycling technology using phase-transfer surfactant and SWATH-MS (2020) (0)
EVALUATION OF DONOR DEPEDENCIES IN PROTEIN EXPRESSION OF TRANSPORTERS AND METABLIC ENZYMES IN HUMANIZED LIVER OF CHIMERIC MICE (2010) (0)
Mouse "reduced in osteosclerosis" transporter (Roct) functions as an organic anion transporter 3 (mOAT3) and is localized at abluminal membrane of blood-brain barrier (2004) (0)
[OPINION]Towards A New Sunrise in the Brain Drug Delivery Research (2019) (0)
PROTEIN QUNATIFICATION IS USEFUL FOR ANALYZING THE INTERINDIVIDUAL DIFFERNECES IN HUMAN LIVER FUNCTION (2010) (0)
Quantitative Targeted Absolute Proteomics (QTAP)-based Pharmacoproteomics: The Importance of International Collaboration. (2017) (0)
CBMT-18. THE ROLE OF BIOMARKER CANDIDATE GELSOLIN AND ITS MICRORNAS IN GLIOBLASTOMA (2019) (0)
Protective Role of Heme Oxygenase–1 Against High Glucose and Oxidative–Nitrosative Stress in Retinal Endothelial Cells (2006) (0)
Attenuation of Phosphorylation by Deoxycytidine Kinase is Key to Acquired Gemcitabine Resistance in a Pancreatic Cancer Cell Line: Targeted Proteomic and Metabolomic Analyses in PK9 Cells (2012) (0)
Atmospheric-pressure plasma-induced cellular responses in human colorectal adenocarcinoma Caco-2 cells: A study of comprehensive quantitative proteomics (2016) (0)

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What Schools Are Affiliated With Tetsuya Terasaki?

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