Tim Hubbard

Tim Hubbard's AcademicInfluence.com Rankings

Tim Hubbard

Biology

#1426

World Rank

#2397

Historical Rank

Bioinformatics

#32

World Rank

#32

Historical Rank

biology Degrees

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Biology

Why Is Tim Hubbard Influential?

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According to Wikipedia, Timothy John Phillip Hubbard is a Professor of Bioinformatics at King's College London, Head of Genome Analysis at Genomics England and Honorary Faculty at the Wellcome Trust Sanger Institute in Cambridge, UK. Starting March 1, 2024, Tim will become the director of Europe's Life Science Data Infrastructure ELIXIR.

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Tim Hubbard's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Initial sequencing and analysis of the human genome. (2001) (15222)
SCOP: a structural classification of proteins database for the investigation of sequences and structures. (1995) (6550)
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (2007) (5196)
Initial sequencing and comparative analysis of the mouse genome. (2002) (4609)
Landscape of transcription in human cells (2012) (4392)
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression (2012) (4237)
GENCODE: The reference human genome annotation for The ENCODE Project (2012) (4009)
The zebrafish reference genome sequence and its relationship to the human genome (2013) (3401)
A census of human cancer genes (2004) (3087)
The ENCODE (ENCyclopedia Of DNA Elements) Project (2004) (2194)
An integrated encyclopedia of DNA elements in the human genome (2012) (2080)
GENCODE reference annotation for the human and mouse genomes (2018) (1848)
International network of cancer genome projects (2010) (1839)
The Ensembl genome database project (2002) (1559)
A User's Guide to the Encyclopedia of DNA Elements (ENCODE) (2011) (1467)
The DNA sequence of human chromosome 22 (1999) (1117)
The DNA sequence of the human X chromosome (2005) (1072)
Data growth and its impact on the SCOP database: new developments (2007) (985)
SCOP database in 2004: refinements integrate structure and sequence family data (2004) (970)
The UK10K project identifies rare variants in health and disease (2015) (926)
SCOP: a structural classification of proteins database (1998) (859)
Ensembl 2014 (2013) (845)
Ensembl 2013 (2012) (663)
GENCODE: producing a reference annotation for ENCODE (2006) (650)
Ensembl 2012 (2011) (648)
Defining functional DNA elements in the human genome (2014) (647)
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis (2008) (647)
Using neural networks for prediction of the subcellular location of proteins. (1998) (609)
Assessment of transcript reconstruction methods for RNA-seq (2013) (608)
Sequence comparisons using multiple sequences detect three times as many remote homologues as pairwise methods. (1998) (587)
Ensembl 2009 (2008) (575)
The consensus coding sequence (CCDS) project: Identifying a common protein-coding gene set for the human and mouse genomes. (2009) (569)
Ensembl 2007 (2006) (553)
DNA sequence and analysis of human chromosome 9 (2003) (548)
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly. (2017) (541)
Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships. (1998) (534)
SCOP database in 2002: refinements accommodate structural genomics (2002) (509)
Systematic evaluation of spliced alignment programs for RNA-seq data (2013) (494)
Ensembl 2011 (2010) (482)
An overview of Ensembl. (2004) (462)
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli (2020) (426)
Modernizing Reference Genome Assemblies (2011) (402)
The Solution Structure of the S1 RNA Binding Domain: A Member of an Ancient Nucleic Acid–Binding Fold (1997) (400)
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). (2008) (399)
The vertebrate genome annotation (Vega) database (2004) (395)
Accurate and sensitive peptide identification with Mascot Percolator. (2009) (375)
Ensembl 2008 (2007) (362)
EGASP: the human ENCODE Genome Annotation Assessment Project (2006) (344)
Critical assessment of methods of protein structure prediction—Round VII (2007) (342)
A physical map of the mouse genome (2002) (338)
Critical assessment of methods of protein structure prediction (CASP)‐round V (2005) (329)
Ensembl’s 10th year (2009) (321)
The GENCODE pseudogene resource (2012) (309)
Computational detection and location of transcription start sites in mammalian genomic DNA. (2002) (299)
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel (2015) (296)
The DNA sequence and comparative analysis of human chromosome 20 (2004) (280)
Critical assessment of methods of protein structure prediction (CASP): Round II (1997) (276)
Ensembl 2005 (2004) (274)
Comparative Analysis of the Transcriptome across Distant Species (2014) (268)
The DNA sequence and analysis of human chromosome 6 (2003) (266)
Ensembl 2002: accommodating comparative genomics (2003) (257)
Ensembl 2006 (2005) (255)
SCOP: a Structural Classification of Proteins database (1999) (254)
Knowledge‐based protein modelling and design (1988) (245)
GENCODE 2021 (2020) (240)
Intermediate sequences increase the detection of homology between sequences. (1997) (234)
Evidence for Transcript Networks Composed of Chimeric RNAs in Human Cells (2012) (233)
The 100 000 Genomes Project: bringing whole genome sequencing to the NHS (2018) (206)
Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. (2007) (206)
Making sense of big data in health research: Towards an EU action plan (2016) (205)
Comparison of solvent-inaccessible cores of homologous proteins: definitions useful for protein modelling. (1987) (191)
Large-Scale Mutagenesis in p19ARF- and p53-Deficient Mice Identifies Cancer Genes and Their Collaborative Networks (2008) (190)
Prepublication data sharing (2009) (190)
Global implementation of genomic medicine: We are not alone (2015) (183)
Population statistics of protein structures: lessons from structural classifications. (1997) (171)
Critical assessment of methods of protein structure prediction (CASP): Round IV (2003) (170)
The DNA sequence and biological annotation of human chromosome 1 (2006) (166)
Current status and new features of the Consensus Coding Sequence database (2013) (156)
Characterisation of mental health conditions in social media using Informed Deep Learning (2017) (154)
Analysis and assessment of ab initio three‐dimensional prediction, secondary structure, and contacts prediction (1999) (154)
SCOP: a Structural Classification of Proteins database (2000) (140)
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage (2006) (138)
NestedMICA: sensitive inference of over-represented motifs in nucleic acid sequence (2005) (135)
Critical assessment of methods of protein structure prediction (CASP): round III. (1997) (130)
The DNA sequence and biological annotation of human chromosome 1 (2006) (127)
Ensembl 2004 (2004) (123)
Shotgun proteomics aids discovery of novel protein-coding genes, alternative splicing, and "resurrected" pseudogenes in the mouse genome. (2011) (119)
Petabyte-scale innovations at the European Nucleotide Archive (2008) (116)
Integrating biological data – the Distributed Annotation System (2008) (113)
Understanding protein structure: using scop for fold interpretation. (1996) (110)
Dalliance: interactive genome viewing on the web (2011) (106)
Erratum: Initial sequencing and analysis of the human genome: International Human Genome Sequencing Consortium (Nature (2001) 409 (860-921)) (2001) (106)
Critical assessment of methods of protein structure prediction (CASP)—Round 6 (2005) (106)
Assessment of novel fold targets in CASP4: Predictions of three‐dimensional structures, secondary structures, and interresidue contacts (2001) (101)
Protein folds in the all-beta and all-alpha classes. (1997) (97)
The 100,000 Genomes Project Protocol (2017) (93)
Large-Scale Discovery of Promoter Motifs in Drosophila melanogaster (2006) (87)
Integrating sequence and structural biology with DAS (2007) (86)
Critical assessment of methods of protein structure prediction (CASP): round IV. (2001) (86)
Gene duplications in H. influenzae (1995) (86)
Perspectives on ENCODE (2020) (79)
SISYPHUS—structural alignments for proteins with non-trivial relationships (2006) (79)
Domain insertions in protein structures. (2004) (76)
The DNA sequence and analysis of human chromosome 13 (2004) (75)
The language of mental health problems in social media (2016) (73)
ddbRNA: detection of conserved secondary structures in multiple alignments (2003) (72)
The GENCODE exome: sequencing the complete human exome (2011) (71)
Priorities for nucleotide trace, sequence and annotation data capture at the Ensembl Trace Archive and the EMBL Nucleotide Sequence Database (2007) (71)
A Comparison of Peak Callers Used for DNase-Seq Data (2014) (71)
The Origins, Evolution, and Functional Potential of Alternative Splicing in Vertebrates (2011) (70)
Mining the draft human genome (2001) (70)
A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans (2014) (69)
Comparison of Mascot and X!Tandem Performance for Low and High Accuracy Mass Spectrometry and the Development of an Adjusted Mascot Threshold*S (2008) (68)
Chromatin Accessibility Data Sets Show Bias Due to Sequence Specificity of the DNase I Enzyme (2013) (65)
The DNA sequence and comparative analysis of human chromosome 10 (2004) (65)
Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans (2020) (64)
Comparative analysis of pseudogenes across three phyla (2014) (63)
Combining RT-PCR-seq and RNA-seq to catalog all genic elements encoded in the human genome (2012) (60)
Adding Some SPICE to DAS (2005) (58)
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage (2021) (51)
RMS/Coverage graphs: A qualitative method for comparing three‐dimensional protein structure predictions (1999) (50)
Characterizing genetic variants for clinical action (2014) (48)
Discovery of Candidate Disease Genes in ENU–Induced Mouse Mutants by Large-Scale Sequencing, Including a Splice-Site Mutation in Nucleoredoxin (2009) (47)
Lessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 Mb region of pig chromosome 17 (2007) (46)
Human and mouse essentiality screens as a resource for disease gene discovery (2019) (45)
BioJava: open source components for bioinformatics (2000) (45)
NestedMICA as an ab initio protein motif discovery tool (2008) (43)
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (43)
Gathering them in to the fold (1996) (42)
Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach. (2010) (42)
SCOP, Structural Classification of Proteins database: applications to evaluation of the effectiveness of sequence alignment methods and statistics of protein structural data. (1998) (41)
Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis (2020) (40)
Genomic anatomy of the Tyrp1 (brown) deletion complex. (2006) (37)
Critical assessment of methods of protein structure prediction (CASP): Round III (1999) (33)
Developing and implementing an institute-wide data sharing policy (2011) (32)
Use of /spl beta/-strand interaction pseudo-potentials in protein structure prediction and modelling (1994) (32)
Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis (2019) (31)
Protein engineering and design. (1989) (31)
18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design. (1988) (31)
Numerical criteria for the evaluation of ab initio predictions of protein structure (1997) (30)
The Protein Feature Ontology: a tool for the unification of protein feature annotations (2008) (29)
Open annotation offers a democratic solution to genome sequencing (2000) (29)
CASP5 target classification (2003) (27)
New tools and expanded data analysis capabilities at the protein structure prediction center (2007) (27)
Databases and tools for browsing genomes. (2002) (26)
DYNC2H1 hypomorphic or retina-predominant variants cause nonsyndromic retinal degeneration (2020) (26)
Heterozygous lamin B1 and lamin B2 variants cause primary microcephaly and define a novel laminopathy (2020) (25)
Comparison of in silico strategies to prioritize rare genomic variants impacting RNA splicing for the diagnosis of genomic disorders (2020) (25)
Biological information: making it accessible and integrated (and trying to make sense of it) (2002) (25)
Protein design on computers. Five new proteins: Shpilka, grendel, fingerclasp, leather, and aida (1992) (23)
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2018) (22)
Proceedings Of The Third International Conference On Intelligent Systems For Molecular Biology (1995) (22)
Whole genome sequencing for the diagnosis of neurological repeat expansion disorders in the UK: a retrospective diagnostic accuracy and prospective clinical validation study (2022) (22)
Update on protein structure prediction: results of the 1995 IRBM workshop. (1996) (21)
Cancer gene discovery in mouse and man (2009) (21)
Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome (2013) (20)
Genome-wide end-sequenced BAC resources for the NOD/MrkTac☆ and NOD/ShiLtJ☆☆ mouse genomes (2010) (19)
Use of beta-strand Interaction Pseudo-Potentials in Protein Structure Prediction and Modeling (1994) (19)
Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma (2021) (18)
The DNA sequence and biological annotation of human chromosome 1 (vol 441, pg 315, 2006) (2006) (18)
The Distributed Annotation System for Integration of Biological Data (2006) (18)
ITFoM - The IT Future of Medicine (2011) (17)
What can we learn from noncoding regions of similarity between genomes? (2003) (16)
Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease (2014) (15)
An ancestral 10-bp repeat expansion in VWA1 causes recessive hereditary motor neuropathy (2021) (14)
A machine learning strategy to identify candidate binding sites in human protein-coding sequence (2006) (14)
An interactive genome browser of association results from the UK10K cohorts project (2015) (14)
Transcriptional activity and strain-specific history of mouse pseudogenes (2020) (13)
iMotifs: an integrated sequence motif visualization and analysis environment (2010) (13)
The Vertebrate Genome Annotation (Vega) database (2004) (13)
Erratum to: Making sense of big data in health research: towards an EU action plan (2016) (12)
MaxBench: evaluation of sequence and structure comparison methods (2002) (11)
Prediction targets of CASP4 (2001) (11)
SCOP database in 2002 (2002) (10)
Population statistics of protein structures (1997) (10)
18TH KREBS,HANS LECTURE - KNOWLEDGE-BASED PROTEIN MODELING AND DESIGN (1988) (10)
Genotype–phenotype correlations for COL4A3–COL4A5 variants resulting in Gly substitutions in Alport syndrome (2022) (10)
Evaluating the performance of a clinical genome sequencing program for diagnosis of rare genetic disease, seen through the lens of craniosynostosis (2021) (9)
Mining Social Media Data to Study the Consequences of Dementia Diagnosis on Caregivers and Relatives (2020) (9)
Analysis of diagnoses extracted from electronic health records in a large mental health case register (2017) (9)
Automated PDF highlighting to support faster curation of literature for Parkinson’s and Alzheimer’s disease (2017) (8)
New horizons in sequence analysis. (1997) (8)
The GENCODE human gene set (2010) (8)
Biallelic variants in KARS1 are associated with neurodevelopmental disorders and hearing loss recapitulated by the knockout zebrafish (2021) (7)
The significance of performance ranking in CASP--response to Marti-Renom et al. (2002) (7)
The NHS England 100,000 Genomes Project: feasibility and utility of centralised genome sequencing for children with cancer (2022) (6)
Publisher Correction: Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (2022) (6)
Metamotifs - a generative model for building families of nucleotide position weight matrices (2010) (6)
AnnoTrack - a tracking system for genome annotation (2010) (6)
GENCODE: reference annotation for the human and mouse genomes in 2023 (2022) (5)
SOX11 variants cause a neurodevelopmental disorder with infrequent ocular malformations and hypogonadotropic hypogonadism and with distinct DNA methylation profile. (2022) (5)
Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies (2021) (5)
Corrigendum: Characterisation of mental health conditions in social media using Informed Deep Learning (2017) (5)
Protein structure prediction: playing the fold. (1996) (5)
Understanding protein structure (1996) (5)
Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly (2016) (4)
Assessing the digenic model in rare disorders using population sequencing data (2022) (4)
Update On The Zebrafish Genome Project (2009) (4)
Pharmacogenomic testing in paediatrics: Clinical implementation strategies (2021) (3)
GLASS: A tool to visualize protein structure prediction data in three dimensions and evaluate their consistency (1998) (3)
SPEM: a parser for EMBL style flat file database entries (1998) (3)
Human Genome: Draft Sequence (2005) (2)
Update on protein structure prediction (1996) (2)
Update on protein structure prediction (1996) (2)
A browser for expression data (2000) (2)
Biallelic variants in coenzyme Q10 biosynthesis pathway genes cause a retinitis pigmentosa phenotype (2022) (2)
RMS/coverage graphs (1999) (2)
RMS/coverage graphs (1999) (2)
Challenges and opportunities for system biology standards and tools in medical research (2016) (2)
Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity (2017) (2)
Large-Scale Gene Regulatory Motif Discovery with NestedMICA (2011) (2)
Modelling Protein Structures (2007) (1)
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy (2022) (1)
Identification and analysis of functional elements in 1 % of the human genome by the ENCODE pilot project The ENCODE Project Consortium * (2007) (1)
EGASP: the human ENCODE Genome Annotation Assessment (2015) (1)
The Third Computational Linguistics and Clinical Psychology Workshop (CLPsych) (2016) (1)
AnnoTrack - a tracking system for genome (2010) (1)
Pseudogenes in the mouse lineage: transcriptional activity and strain-specific history (2018) (1)
Mendelian gene identification through mouse embryo viability screening (2022) (1)
Relevance Vector Machines for classifying points and regions in biological sequences. (2003) (1)
Targeting de novo loss-of-function variants in constrained disease genes improves diagnostic rates in the 100,000 Genomes Project (2022) (1)
Expanding SPTAN1 monoallelic variant associated disorders: From epileptic encephalopathy to pure spastic paraplegia and ataxia. (2022) (1)
A Specification for Defining and Annotating Regions of Macromolecular Structures (1995) (1)
From identification to validation to gene count (2010) (1)
Author Correction: Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans (2020) (1)
A Machine Learning Strategy to Identity Exonic Splice Enhancers in Human Protein-coding Sequence (2004) (1)
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume (2019) (1)
Chicken gene annotation in Ensembl (2013) (0)
Author Correction: Perspectives on ENCODE (2022) (0)
De novo design and the synthesis of TIM barrel proteins (1992) (0)
Proposal SAMPLE 1 : Improved Scoring Schemes for Profile-HMMs applied to Protein Analysis (0)
RGASP: assessment of gene-finding tools in the high-throughput era (2010) (0)
Making sense of big data in health research: Towards an EU action plan (2016) (0)
Scientists on the Spot: Sequencing the human genome to influence patient healthcare (2018) (0)
The Human Genome Project (2005) (0)
Pathogenicity of missense variants affecting the collagen IV α5 carboxy non-collagenous domain in X-linked Alport syndrome (2022) (0)
The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision (2022) (0)
Multilocus Inherited Neoplasia Allele Syndrome (MINAS): an update (2022) (0)
The genomic landscape of familial glioma (2023) (0)
Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing (2022) (0)
Whole genome sequencing delineates regulatory, copy number, and cryptic splice variants in early onset cardiomyopathy (2022) (0)
The GENCODE pseudogene resource (2012) (0)
Application of ensemble clustering and survival tree analysis for identifying prognostic clinicogenomic features in patients with colorectal cancer from the 100,000 Genomes Project (2021) (0)
Nuclear-mitochondrial DNA segments resemble paternally inherited mitochondrial DNA in humans (2020) (0)
Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes (2022) (0)
Heterozygous UCHL1 loss-of-function variants cause a neurodegenerative disorder with spasticity, ataxia, neuropathy, and optic atrophy. (2022) (0)
Density Networks with Application to Protein Modelling Statement regarding Originality of Thesis (1998) (0)
Human and mouse essentiality screens as a resource for disease gene discovery (2020) (0)
GENCODE: Creating a Validated Manually Annotated Geneset for the Whole Human Genome (2009) (0)
UK 10 K Consortium (2019) (0)
Universitet Low-frequency variation in TP 53 has large effects on head circumference and intracranial (2019) (0)

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Tim Hubbard is affiliated with the following schools:

King's College London

Tim Hubbard's Academic­Influence.com Rankings