Walter Fiers

Q: What Schools Are Affiliated With Walter Fiers

Walter Fiers is affiliated with the following schools: Université libre de Bruxelles, Ghent University, University of Antwerp

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Walter Fiers

Biology

#90

World Rank

#158

Historical Rank

Molecular Biology

#32

World Rank

#32

Historical Rank

biology Degrees

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Biology

Walter Fiers's Degrees

PhD Molecular Biology Ghent University
Masters Chemistry Ghent University

Why Is Walter Fiers Influential?

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According to Wikipedia, Walter Fiers was a Belgian molecular biologist. He obtained a degree of Engineer for Chemistry and Agricultural Industries at the University of Ghent in 1954, and started his research career as an enzymologist in the laboratory of Laurent Vandendriessche in Ghent. In 1956–57, he worked with in Copenhagen . In 1960, he obtained a fellowship from the Rockefeller Foundation and joined the group of Bob Sinsheimer as a postdoc. At the California Institute of Technology Walter Fiers was exposed to Molecular Biology, which was then just developing, studying viral DNA. He demonstrated the physical, covalently closed circularity of Bacteriophage PhiX-174 DNA. In 1962, Fiers moved to Madison, Wisconsin, to work in the laboratory of future Nobel laureate, Gobind Khorana.

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Walter Fiers's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role (1991) (1744)
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon. (1986) (1438)
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. (2000) (1415)
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. (1986) (1099)
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation. (1992) (962)
Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor (1998) (900)
More than one way to die: apoptosis, necrosis and reactive oxygen damage (1999) (893)
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia (1993) (863)
Two tumour necrosis factor receptors: structure and function. (1995) (814)
The complete DNA sequence of yeast chromosome III (1992) (804)
Complete nucleotide sequence of SV40 DNA (1978) (802)
Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells. (1986) (757)
p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways Are Required for Nuclear Factor-κB p65 Transactivation Mediated by Tumor Necrosis Factor* (1998) (744)
A universal influenza A vaccine based on the extracellular domain of the M2 protein (1999) (741)
Tumor necrosis factor Characterization at the molecular, cellular and in vivo level (1991) (722)
Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes. (1982) (721)
The p38/RK mitogen‐activated protein kinase pathway regulates interleukin‐6 synthesis response to tumor necrosis factor. (1996) (708)
Complete nucleotide sequence of bacteriophage MS2 RNA: primary and secondary structure of the replicase gene (1976) (679)
Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis (1995) (638)
Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. (1995) (618)
Ia expression by vascular endothelium is inducible by activated T cells and by human gamma interferon (1983) (589)
Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene‐inductive effects of TNF. (1993) (579)
Dual Signaling of the Fas Receptor: Initiation of Both Apoptotic and Necrotic Cell Death Pathways (1998) (563)
Plasmid vectors for high-efficiency expression controlled by the PL promoter of coliphage lambda. (1981) (543)
Immune interferon activates multiple class II major histocompatibility complex genes and the associated invariant chain gene in human endothelial cells and dermal fibroblasts. (1984) (530)
A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific α chain and a β chain shared with the receptor for GM-CSF (1991) (525)
Lymphocytes recognize human vascular endothelial and dermal fibroblast Ia antigens induced by recombinant immune interferon (1983) (468)
Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro. (1986) (464)
Nucleotide Sequence of the Gene Coding for the Bacteriophage MS2 Coat Protein (1972) (439)
EVIDENCE FOR TUMOUR NECROSIS FACTOR/CACHECTIN PRODUCTION IN CANCER (1987) (429)
Activation of cultured human endothelial cells by recombinant lymphotoxin: comparison with tumor necrosis factor and interleukin 1 species. (1987) (422)
Recombinant tumor necrosis factor and immune interferon act singly and in combination to reorganize human vascular endothelial cell monolayers. (1986) (410)
Glucocorticoid-mediated repression of nuclear factor-kappaB-dependent transcription involves direct interference with transactivation. (1997) (402)
Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro. (1991) (387)
ESM-1 Is a Novel Human Endothelial Cell-specific Molecule Expressed in Lung and Regulated by Cytokines* (1996) (348)
TUMOR NECROSIS FACTOR INCREASES THE PRODUCTION OF PLASMINOGEN ACTIVATOR INHIBITOR IN HUMAN ENDOTHELIAL CELLS IN VITRO AND IN RATS IN VIVO (1988) (340)
Structural analysis of the sequence coding for an inducible 26-kDa protein in human fibroblasts. (1986) (328)
Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma. (1986) (323)
Atractyloside‐induced release of cathepsin B, a protease with caspase‐processing activity (1998) (310)
Improved plasmid vectors with a thermoinducible expression and temperature-regulated runaway replication. (1983) (295)
The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors. (1987) (294)
Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40. (1975) (289)
Recombinant interleukin-2 directly augments the cytotoxicity of human monocytes (1987) (289)
Preparative two-dimensional polyacrylamide gel electrophoresis of 32 P-labeled RNA. (1972) (288)
The Zinc Finger Protein A20 Inhibits TNF-induced NF-κB–dependent Gene Expression by Interfering with an RIP- or TRAF2-mediated Transactivation Signal and Directly Binds to a Novel NF-κB–inhibiting Protein ABIN (1999) (284)
M2e-based universal influenza A vaccine. (2009) (276)
Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex. (1986) (276)
Molecular cloning of human interleukin 2 cDNA and its expression in E. coli (1983) (276)
The antitumor function of tumor necrosis factor (TNF), I. Therapeutic action of TNF against an established murine sarcoma is indirect, immunologically dependent, and limited by severe toxicity (1988) (273)
Is amyloidogenesis during Alzheimer's disease due to an IL-1-/IL-6-mediated 'acute phase response' in the brain? (1991) (272)
Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines. (1986) (271)
Universal Vaccine Based on Ectodomain of Matrix Protein 2 of Influenza A: Fc Receptors and Alveolar Macrophages Mediate Protection (2011) (269)
Molecular mechanisms of tumor necrosis factor‐induced cytotoxicity (1994) (257)
A "universal" human influenza A vaccine. (2004) (255)
Cell death induction by receptors of the TNF family: towards a molecular understanding (1997) (252)
Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome (1986) (252)
Isolation and structure of a human fibroblast interferon gene (1980) (250)
Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75 (1980) (233)
Universal influenza A vaccine: optimization of M2-based constructs. (2005) (230)
Human tumor xenografts treated with recombinant human tumor necrosis factor alone or in combination with interferons. (1986) (223)
Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria (2001) (220)
Interferons as macrophage-activating factors. III. Preferential effects of interferon-gamma on the interleukin 1 secretory potential of fresh or aged human monocytes. (1985) (215)
Characterization of seven murine caspase family members (1997) (209)
Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis. (1992) (206)
Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments (2009) (205)
Crucial role of tumor necrosis factor (TNF) receptor 2 and membrane‐bound TNF in experimental cerebral malaria (1997) (201)
The proteolytic procaspase activation network: an in vitro analysis (1999) (196)
B cell growth modulating and differentiating activity of recombinant human 26‐kd protein (BSF‐2, HuIFN‐beta 2, HPGF). (1987) (195)
Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA (1980) (194)
Down‐regulation of E‐cadherin expression in madin darby canine kidney (MDCK) cells inside tumors of nude mice (1991) (189)
Tumor necrosis factor induces the production of urokinase-type plasminogen activator by human endothelial cells. (1990) (188)
Human TNF mutants with selective activity on the p55 receptor (1993) (185)
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells. (1995) (184)
In vivo anti‐tumour activity of recombinant human and murine TNF, alone and in combination with murine IFN‐γ, on a syngeneic murine melanoma (1986) (176)
Expression of human fibroblast interferon gene in Escherichia coli (1980) (175)
Interferon-Inducible Protein Mx1 Inhibits Influenza Virus by Interfering with Functional Viral Ribonucleoprotein Complex Assembly (2012) (174)
The 55-kDa Tumor Necrosis Factor Receptor Induces Clustering of Mitochondria through Its Membrane-proximal Region* (1998) (174)
Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses. (1998) (171)
Secondary structure of mRNA and efficiency of translation initiation. (1980) (170)
The structure of the DNA of bacteriophage phi-X174. III. Ultracentrifugal evidence for a ring structure. (1962) (168)
Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells. (1982) (167)
Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts. (1987) (166)
Cloned human interferon-gamma, but not interferon-beta or -alpha, induces expression of HLA-DR determinants by fetal monocytes and myeloid leukemic cell lines. (1984) (162)
Recombination signal sequence binding protein Jkappa is constitutively bound to the NF-kappaB site of the interleukin-6 promoter and acts as a negative regulatory factor (1997) (161)
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells. (1997) (160)
Complete structure of A/duck/Ukraine/63 influenza hemagglutinin gene: Animal virus as progenitor of human H3 Hong Kong 1968 influenza hemagglutinin (1981) (160)
Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75. (1998) (153)
The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation. (1987) (149)
Cathepsin B-mediated activation of the proinflammatory caspase-11. (1998) (149)
The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases (1999) (147)
Expression and characterization of the product of a human immune interferon cDNA gene in Chinese hamster ovary cells. (1983) (146)
Identification of a new caspase homologue: caspase-14 (1998) (145)
Dissociation of TNF‐alpha cytotoxic and proinflammatory activities by p55 receptor‐ and p75 receptor‐selective TNF‐alpha mutants. (1994) (145)
Binding of human tumor necrosis factor to high affinity receptors on HeLa and lymphoblastoid cells sensitive to growth inhibition. (1985) (142)
Cleavage of PITSLRE Kinases by ICE/CASP-1 and CPP32/CASP-3 during Apoptosis Induced by Tumor Necrosis Factor* (1997) (141)
Protection by alpha 1-acid glycoprotein against tumor necrosis factor- induced lethality (1994) (140)
Recombinant tumour necrosis factor inhibits malaria parasites in vivo but not in vitro. (1987) (139)
Generation and Biological Characterization of Membrane-bound, Uncleavable Murine Tumor Necrosis Factor (*) (1995) (138)
An Influenza A Vaccine Based on Tetrameric Ectodomain of Matrix Protein 2* (2008) (138)
Redox regulation of TNF signaling (1999) (135)
DNA fragmentation and cytotoxicity caused by tumor necrosis factor is enhanced by interferon‐γ (1987) (134)
Tumor necrosis factor and lymphotoxin (1998) (133)
CTA1-M2e-DD: a novel mucosal adjuvant targeted influenza vaccine. (2008) (132)
Three distinct classes of regulatory cytokines control endothelial cell MHC antigen expression. Interactions with immune gamma interferon differentiate the effects of tumor necrosis factor and lymphotoxin from those of leukocyte alpha and fibroblast beta interferons (1988) (131)
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma (1992) (129)
Tumor necrosis factor, its receptors and the connection with interleukin 1 and interleukin 6. (1993) (129)
Circulating interleukin 6 during a continuous infusion of tumor necrosis factor and interferon gamma (1989) (128)
The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection. (2006) (127)
Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture. (1987) (126)
Simple, efficient in vitro synthesis of capped RNA useful for direct expression of cloned eukaryotic genes. (1982) (126)
Improved design and intranasal delivery of an M2e-based human influenza A vaccine. (2006) (125)
Genes for IFN-beta-2 (IL-6), tumor necrosis factor, and IL-1 are expressed at high levels in the organs of normal individuals. (1988) (125)
M2e-Based Universal Influenza A Vaccines (2015) (125)
A-Protein gene of bacteriophage MS2 (1975) (124)
Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit. (1992) (122)
Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration. (1993) (122)
Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity. (1993) (113)
Tight Transcriptional Control Mechanism Ensures Stable High-Level Expression from T7 Promoter-Based Expression Plasmids (1995) (112)
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis. (1995) (111)
Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta. (1982) (110)
A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. (1991) (110)
Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism. (1987) (110)
Alpha 1-acid glycoprotein and alpha 1-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice. (1997) (109)
Analysis of 32P-labeled bacteriophage MS2 RNA by a mini-fingerprinting procedure. (1976) (109)
Inefficient translation initiation causes premature transcription termination in the IacZ gene (1986) (108)
alpha1-Antitrypsin inhibits the lethal response to TNF in mice. (1996) (108)
Role of tumor necrosis factor in flavone acetic acid-induced tumor vasculature shutdown. (1990) (107)
Universal influenza A M2e-HBc vaccine protects against disease even in the presence of pre-existing anti-HBc antibodies. (2008) (104)
Paradoxical effects of tumour necrosis factor in experimental ovarian cancer (1989) (102)
Cell membrane permeabilization and cellular collapse, followed by loss of dehydrogenase activity: early events in tumour necrosis factor-induced cytotoxicity. (1993) (101)
Localization of the active site of human tumour necrosis factor (hTNF) by mutational analysis. (1991) (101)
Recombinant tumor necrosis factor: species specificity for a variety of human and murine transformed cell lines. (1986) (100)
Efficient KEX2-Like Processing of a Glucoamylase-Interleukin-6 Fusion Protein by Aspergillus Nidulans and Secretion of Mature Interleukin-6 (1991) (98)
Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential (2000) (97)
Lysis gene expression of RNA phage MS2 depends on a frameshift during translation of the overlapping coat protein gene (1982) (94)
Secretion of biologically active murine interleukin-2 by Lactococcus lactis subsp. lactis (1995) (93)
Nucleotide sequence of the Hind-C fragment of simian virus 40 DNA. Comparison of the 5'-untranslated region of wild-type virus and of some deletion Mutants. (1979) (93)
Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone. (1991) (93)
Inducible high level synthesis of mature human fibroblast interferon in Escherichia coli. (1983) (90)
Structural characterization of N-linked oligosaccharides from cellobiohydrolase I secreted by the filamentous fungus Trichoderma reesei RUTC 30. (1997) (90)
Recombinant neuraminidase vaccine protects against lethal influenza. (1996) (89)
Hypothermia and hypoglycemia induced by anti‐CD3 monoclonal antibody in mice: Role of tumor necrosis factor (1990) (89)
Micro thin-layer techniques for rapid sequence analysis of 32P-labeled RNA: double digestion and pancreatic ribonuclease analyses. (1977) (89)
M2-based influenza vaccines: recent advances and clinical potential (2017) (88)
Intraperitoneal secretion of interleukin-6 during continuous ambulatory peritoneal dialysis. (1990) (88)
Lithium chloride potentiates tumor necrosis factor-mediated cytotoxicity in vitro and in vivo. (1989) (87)
Induction and regulation of mRNA encoding 26-kDa protein in human cell lines treated with recombinant human tumor necrosis factor. (1987) (86)
Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen. (1998) (85)
Species specificity of human and murine tumor necrosis factor. A comparative study of tumor necrosis factor receptors. (1986) (85)
Limited involvement of interleukin‐6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin‐6 or its receptor in various murine models (1992) (83)
High-level expression of human interferon gamma in Escherichia coli under control of the pL promoter of bacteriophage lambda. (1984) (82)
Recombinant soluble human interleukin-5 (hIL-5) receptor molecules. Cross-linking and stoichiometry of binding to IL-5. (1993) (81)
The structure of the DNA of bacteriophage phi-X174. I. The action of exopolynucleotidases. (1962) (81)
The Oxidative Metabolism of Glutamine (1996) (81)
Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se. (1991) (80)
Protection of mice against a lethal influenza challenge by immunization with yeast-derived recombinant influenza neuraminidase. (1997) (80)
Molecular basis of a high affinity murine interleukin‐5 receptor. (1991) (79)
Cross-talk between steroids and NF-κB: what language? (1998) (78)
Response of interleukin‐6‐deficient mice to tumor necrosis factor‐induced metabolic changes and lethality (1994) (77)
Characterization of interleukin 5 receptors on eosinophilic sublines from human promyelocytic leukemia (HL-60) cells (1990) (75)
Casein Kinase-1 Phosphorylates the p75 Tumor Necrosis Factor Receptor and Negatively Regulates Tumor Necrosis Factor Signaling for Apoptosis (*) (1995) (75)
Recombinant human tumour necrosis factor (rTNF)2 enhances leukotriene biosynthesis in neutrophils and eosinophils stimulated with the Ca2+ ionophore A23187. (1987) (73)
Total nucleotide sequence of a nearly full-size DNA copy of satellite tobacco necrosis virus RNA. (1980) (73)
Alterations upstream from the Shine-Dalgarno region and their effect on bacterial gene expression. (1985) (72)
Search for mediators of the lipogenic effects of tumor necrosis factor: potential role for interleukin 6. (1990) (72)
Structure-activity studies of human tumour necrosis factors. (1994) (71)
Transformation of Aspergillus niger with the homologous nitrate reductase gene. (1989) (71)
Induction of interleukin 6 by human and murine recombinant interleukin 1 in mice (1990) (71)
Systematic alteration of the nucleotide sequence preceding the translation initiation codon and the effects on bacterial expression of the cloned SV40 small-t antigen gene. (1982) (70)
Evidence for a unique human fibroblast interferon (IFN-beta 1) chromosomal gene, devoid of intervening sequences. (1981) (69)
Studies on the bacteriophage MS2. The untranslated 5'-terminal nucleotide sequence preceding the first cistron. (1971) (69)
Regulation of microsomal triglyceride transfer protein mRNA expression by endotoxin and cytokines. (1998) (68)
Synergistic induction of endothelial tissue factor by tumor necrosis factor and vascular endothelial growth factor: functional analysis of the tumor necrosis factor receptors (1996) (68)
Endocytic pathway of recombinant murine tumor necrosis factor in L-929 cells. (1988) (68)
Tumor necrosis factor-alpha induces the phosphorylation of 28kDa stress proteins in endothelial cells: possible role in protection against cytotoxicity? (1989) (67)
Induced Expression of Trimerized Intracellular Domains of the Human Tumor Necrosis Factor (TNF) p55 Receptor Elicits TNF Effects (1997) (67)
Therapeutic Potential of Tumor Necrosis Factor-α and γ-Interferon in Experimental Human Ovarian Cancer (1987) (66)
Involvement of a serine protease in tumour-necrosis-factor-mediated cytotoxicity. (1988) (66)
Involvement of the liver, but not of IL-6, in IL-1-induced desensitization to the lethal effects of tumor necrosis factor. (1991) (66)
M2e-tetramer-specific memory CD4 T cells are broadly protective against influenza infection (2017) (66)
[7] Fractionation of RNA by electrophoresis on polyacrylamide gel slabs (1971) (65)
Interactions of T lymphocytes with human vascular endothelial cells: role of endothelial cells surface antigens. (1984) (65)
Functional Display of a Heterologous Protein on the Surface of Lactococcus lactis by Means of the Cell Wall Anchor of Staphylococcus aureus Protein A (1998) (65)
Studies on the bacteriophage MS2. I. Distribution of purine sequences in the viral RNA and in yeast RNA. (1965) (64)
Fab Chains As an Efficient Heterodimerization Scaffold for the Production of Recombinant Bispecific and Trispecific Antibody Derivatives1 (2000) (64)
Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin. (1999) (63)
Inflammatory properties of recombinant tumor necrosis factor in rabbit skin in vivo (1989) (63)
Cloning and structure of the human immune interferon‐gamma chromosomal gene. (1982) (63)
Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway. (1992) (63)
Evidence for the direct involvement of DNA replication origin in synthesis of late SV40 RNA (1982) (62)
Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF. (1999) (61)
Tumor necrosis factor and the systemic inflammatory response syndrome. (1996) (60)
Initiation of transcription by RNA polymerase II in permeable, SV40-infected or noninfected, CVI cells; evidence for multiple promoters of SV40 late transcription. (1981) (59)
Modulation of tumor necrosis factor-alpha cytotoxicity in L929 cells by bacterial toxins, hydrocortisone and inhibitors of arachidonic acid metabolism. (1987) (58)
Human cytolytic T lymphocyte interactions with vascular endothelium and fibroblasts: role of effector and target cell molecules. (1984) (58)
Codon usage and mistranslation. In vivo basal level misreading of the MS2 coat protein message. (1983) (58)
Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase. (2000) (57)
TRAF2 plays a dual role in NF‐κB‐dependent gene activation by mediating the TNF‐induced activation of p38 MAPK and IκB kinase pathways (1998) (57)
A micromethod for base analysis of 32P-labeled oligoribonulcleotides. (1977) (56)
Tumor necrosis factor‐α augmented tumor response in B16BL6 melanoma‐bearing mice treated with stealth liposomal doxorubicin (Doxil®) correlates with altered Doxil® pharmacokinetics (2004) (56)
Selective species specificity of tumor necrosis factor for toxicity in the mouse. (1992) (55)
Expression of an exogenous tumor necrosis factor (TNF) gene in TNF-sensitive cell lines confers resistance to TNF-mediated cell lysis. (1992) (55)
Abnormal glutathione and sulfate levels after interleukin 6 treatment and in tumor‐induced cachexia (1996) (55)
Single-Domain Antibodies Targeting Neuraminidase Protect against an H5N1 Influenza Virus Challenge (2014) (55)
Cleavage map of the simian-virus-40 genome by the restriction endonuclease III of Haemopholus aegyptius. (1976) (54)
A Method for Fast and Pure DNA Elution from Agarose Gels by Centrifugal Filtration (1985) (54)
Defective IFN-gamma production in the human neonate. II. Role of increased sensitivity to the suppressive effects of prostaglandin E. (1985) (54)
Heterologous gene expression by filamentous fungi: secretion of human interleukin-6 by Aspergillus nidulans. (1990) (54)
Two discrete types of tumor necrosis factor-resistant cells derived from the same cell line. (1991) (53)
Overlapping of the VP2-VP3 gene and the VP1 gene in the SV40 genome (1977) (52)
Complete nucleotide sequence of the influenza B/Singapore/222/79 virus hemagglutinin gene and comparison with the B/Lee/40 hemagglutinin. (1983) (52)
Cleavage of caspase family members by granzyme B: a comparative study in vitro (1997) (52)
Identification of caspases that cleave presenilin‐1 and presenilin‐2 (1999) (52)
Methylprednisolone differentially regulates IL‐10 and tumour necrosis factor (TNF) production during murine endotoxaemia (1996) (51)
Molecular mechanisms of nucleotide-sequence rearrangements in cDNA clones of human fibroblast interferon mRNA. (1981) (51)
Characterization of critical residues in the cytoplasmic domain of the human interleukin‐5 receptor α chain required for growth signal transduction (1995) (51)
Nuclear magnetic resonance analysis of tumor necrosis factor-induced alterations of phospholipid metabolites and pH in Friend leukemia cell tumors and fibrosarcomas in mice. (1987) (50)
Detailed analysis of the IL‐5‐IL‐5R alpha interaction: characterization of crucial residues on the ligand and the receptor. (1995) (50)
Rapid phosphorylation of a 27 kDa protein induced by tumor necrosis factor (1988) (50)
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF. (1995) (50)
Nucleotide sequence of the chromosomal gene for human fibroblast (beta 1) interferon and of the flanking regions. (1981) (50)
Four different interleukin-1 species sensitize to the lethal action of tumour necrosis factor. (1989) (50)
A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus. (2011) (50)
TNF receptor p55 plays a major role in centrally mediated increases of serum IL-6 and corticosterone after intracerebroventricular injection of TNF. (1996) (50)
Specific binding of eukaryotic initiation factor 2 to satellite tobacco necrosis virus RNA at a 5'-terminal sequence comprising the ribosome binding site. (1981) (50)
Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody (2015) (50)
Human dermal fibroblasts present tetanus toxoid antigen to antigen-specific T cell clones. (1985) (49)
Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha. (1991) (49)
Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor. (1994) (49)
Expression of the tumor necrosis factor gene in tumor cells correlates with reduced tumorigenicity and reduced invasiveness in vivo. (1991) (49)
Structural studies of the carbohydrate chains of human gamma-interferon. (1986) (49)
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein (2014) (49)
Autocrine secretion of tumor necrosis factor under the influence of interferon-gamma amplifies HLA-DR gene induction in human monocytes. (1988) (47)
Natural and long-lasting cellular immune responses against influenza in the M2e-immune host (2012) (47)
Invasiveness and metastatic capability of rat fibroblast-like cells before and after transfection with immortalizing and transforming genes. (1986) (47)
Characterization of soluble factors that induce the cytolytic activity and the expression of T cell growth factor receptors of a T cell hybrid (1984) (47)
A20, an inhibitor of cell death, self‐associates by its zinc finger domain (1996) (46)
Tumor necrosis factor and interleukin 1 activate phospholipase in rat chondrocytes (1988) (46)
Growth inhibition and cytotoxicity of tumor necrosis factor in L929 cells is enhanced by high cell density and inhibition of mRNA synthesis. (1986) (45)
Tumor necrosis factor : molecular and cellular biology and clinical relevance (1993) (45)
On codon usage (1979) (45)
Pandemic preparedness: toward a universal influenza vaccine. (2009) (45)
Recombinant IL-1 receptor antagonist protects against TNF-induced lethality in mice. (1994) (45)
Nucleotide sequence deletions within the coding region for small-t antigen of simian virus 40 (1979) (44)
Long-Lasting Cross-Protection Against Influenza A by Neuraminidase and M2e-based immunization strategies (2016) (44)
Biologic therapy with TNF: preclinical studies (1995) (43)
Complete nucleotide sequence of a human influenza neuraminidase gene of subtype N2 (A/Victoria/3/75). (1982) (43)
Sequences at the 5′-Terminus of Bacteriophage Qβ RNA (1969) (43)
Improved localization of phosphorylation sites in simian virus 40 large T antigen (1983) (43)
M2e-Displaying Virus-Like Particles with Associated RNA Promote T Helper 1 Type Adaptive Immunity against Influenza A (2013) (42)
Proteolytic cleavage of β‐catenin by caspases: an in vitro analysis (1999) (42)
High-level transient expression of influenza virus proteins from a series of SV40 late and early replacement vectors. (1988) (41)
The structure of the DNA of bacteriophage phi-X174. II. Thermal inactivation. (1962) (41)
A20 Inhibits NF-κB Activation Independently of Binding to 14-3-3 Proteins (1997) (41)
Versatile, multi-featured plasmids for high-level expression of heterologous genes in Escherichia coli: overproduction of human and murine cytokines. (1995) (41)
Evidence for ‘splicing’ of SV40 16S mRNA (1978) (40)
Bacteriophage Ms2 RNA: nucleotide sequence of the end of the a protein gene and the intercistronic region. (1973) (40)
The structure of mouse tumour-necrosis factor at 1.4 A resolution: towards modulation of its selectivity and trimerization. (1999) (40)
MODULATION OF THE RELEASE OF CYTOKINES AND REDUCTION OF THE SHOCK SYNDROME INDUCED BY ANTI‐CD3 MONOCLONAL ANTIBODY IN MICE BY INTERLEUKIN‐10 (1994) (40)
Production of soluble and active recombinant murine interleukin-2 in Escherichia coli: high level expression, Kil-induced release, and purification. (1995) (40)
Folding of the MS2 coat protein in Escherichia coli is modulated by translational pauses resulting from mRNA secondary structure and codon usage: a hypothesis. (1993) (40)
Use of monoclonal antibodies to detect human placental alkaline phosphatase. (1983) (40)
Production and purification of recombinant human interleukin-6 secreted by the yeast Saccharomyces cerevisiae. (1991) (39)
Construction and characterization of a plasmid containing a nearly full-size DNA copy of bacteriophage MS2 RNA. (1979) (39)
Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti‐Fas antibodies (1998) (39)
Expression of human and murine interleukin-5 in eukaryotic systems. (1989) (39)
Recombinant tumor necrosis factor can induce interleukin 2 receptor expression and cytolytic activity in a rat × mouse T cell hybrid (1987) (39)
Functional Characterization of the Prodomain of Interleukin1β-converting Enzyme* (1996) (39)
Structure and Function of RNA Bacteriophages (1979) (39)
Effects of interleukin-6 and leukemia inhibitory factor on the acute phase response and DNA synthesis in cultured rat hepatocytes. (1991) (38)
Heterogeneity of the 5' terminus of late mRNA induced by a viable simian virus 40 deletion mutant (1979) (38)
Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth factor withdrawal (1997) (38)
Recent progress in the sequence determination of bacteriophage MS2 RNA. (1971) (38)
Endothelial-Dependent Mechanisms of Leukocyte Adhesion: Regulation by Interleukin-1 and Tumor Necrosis Factor (1987) (38)
Specific cleavage and physical mapping of simian-virus-40 DNA by the restriction endonuclease of Arthrobacter luteus. (1976) (38)
Cloning and structure of the human interleukin 2 chromosomal gene. (1983) (37)
The Influence of Modulating Substances on Tumor Necrosis Factor and Interleukin‐6 Levels After Injection of Murine Tumor Necrosis Factor or Lipopolysaccharide in Mice (1991) (37)
Studies on the bacteriophages MS2. XXXIII. Comparison of the nucleotide sequences in related bacteriophage RNAs. (1976) (37)
Toxic effects of recombinant tumor necrosis factor in suckling mice. Comparisons with interferon alpha/beta. (1987) (37)
Studies on the bacteriophage MS2. V. The 5′‐terminal tetranucleotide sequence of the viral RNA chain (1968) (37)
Lymphokines and monokines in anti-cancer therapy. (1986) (36)
Characterization of the 5'-terminal cap structures of early simian virus 40 mRNA (1980) (36)
Studies on the bacteriophage MS2. Nucleotide fragments from the coat protein cistron (1971) (36)
Protection against Influenza A Virus Challenge with M2e-Displaying Filamentous Escherichia coli Phages (2015) (36)
Enhancement of tumor necrosis factor cytotoxicity by lithium chloride is associated with increased inositol phosphate accumulation. (1993) (36)
In vitro conversion of the carbohydrate moiety of fungal glycoproteins to mammalian-type oligosaccharides--evidence for N-acetylglucosaminyltransferase-I-accepting glycans from Trichoderma reesei. (1997) (36)
Molecular cloning and identification of murine caspase-8. (1998) (35)
Localization of the 5' terminus of late SV40 mRNA. (1978) (35)
Inhibition of tumor necrosis factor-induced necrotic cell death by the zinc finger protein A20. (1999) (35)
The initiation region of the SV40 VP1 gene (1976) (34)
The glucocorticoid antagonist RU38486 mimics interleukin‐1 in its sensitization to the lethal and interleukin‐6‐inducing properties of tumor necrosis factor (1992) (34)
Construction of stable laboratory and industrial yeast strains expressing a foreign gene by integrative transformation using a dominant selection system. (1986) (34)
The nucleotide sequence of a third cyclophilin‐homologous gene from Saccharomyces cerevisiae (1991) (34)
Growth of CD34+ acute myeloblastic leukemia colony-forming cells in response to recombinant hematopoietic growth factors. (1990) (34)
Identification of Tumor Necrosis Factor (TNF) Amino Acids Crucial for Binding to the Murine p75 TNF Receptor and Construction of Receptor-selective Mutants* (2001) (34)
Anti‐tumor effects of interferon in mice injected with interferon‐sensitive and interferon‐resistant friend leukemia cells. V. Comparisons with the action of tumor necrosis factor (1986) (33)
Synergistic induction of interleukin‐6 by tumor necrosis factor and lithium chloride in mice: Possible role in the triggering and exacerbation of psoriasis by lithium treatment (1992) (33)
Tumor Necrosis Factor-induced Microtubule Stabilization Mediated by Hyperphosphorylated Oncoprotein 18 Promotes Cell Death* (2000) (33)
The Zinc Finger Protein A 20 Inhibits TNF-induced NFk B – dependent Gene Expression by Interfering with an RIP-or TRAF 2-mediated Transactivation Signal and Directly Binds to a Novel NFk B – inhibiting Protein (1999) (32)
Proteolytic cleavage of beta-catenin by caspases: an in vitro analysis. (1999) (32)
Complete nucleotide sequence of the nucleoprotein gene from the human influenza strain A/PR/8/34 (HON1). (1981) (32)
Deletion mapping of the inducible promoter of human IFN-β gene (1983) (32)
Anti‐tumor activity of recombinant mouse tumor necrosis factor (TNF) on colon cancer in rats is promoted by recombinant rat interferon gamma; toxicity is reduced by indomethacin (1987) (32)
Studies on the bacteriophage MS2. G‐U‐G as the initiation codon of the A‐protein cistron (1973) (32)
The enzymic addition of poly(A) to the 3'-end of RNA using bacteriophage MS 2 RNA as a model system. (1976) (32)
Nucleotide sequence of the simian virus 40 small-t gene. (1978) (32)
Organization and chromosomal localization of the human interleukin 5 receptor alpha-chain gene. (1992) (32)
Dissociation of TNF- cytotoxic and proinflammatory activities by p55 and p75 receptor-selective TNF- mutants (1994) (32)
Recombinant Influenza Virus Carrying the Respiratory Syncytial Virus (RSV) F85-93 CTL Epitope Reduces RSV Replication in Mice (2013) (32)
Efficient secretion of biologically active recombinant OB protein (leptin) in Escherichia coli, purification from the periplasm and characterization. (1998) (31)
A System for Dominant Transformation and Plasmid Amplification in Saccharomyces cerevisiae (1985) (31)
The effect of recombinant human tumour necrosis factor on growth and macromolecular synthesis of human epithelial cells. (1987) (31)
Purification, crystallization and preliminary X-ray data of the bacteriophage MS2. (1986) (30)
Heterotrimers Formed by Tumor Necrosis Factors of Different Species or Muteins* (2001) (30)
Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock. (1999) (30)
Synthesis and maturation of recombinant human tumor necrosis factor in eukaryotic systems (1986) (30)
Tumor necrosis factor cytotoxicity is associated with phospholipase D activation. (1993) (30)
Inhibition by glucocorticoids of tumor necrosis factor‐mediated cytotoxicity (1990) (29)
Tumor necrosis factor induces acute phase proteins in rats. (1987) (29)
Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the region coding for the carboxyl terminus of the T antigen (1979) (28)
Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression. (1991) (28)
Bacteriophage MS2 RNA: A correlation between the stability of the codon: Anticodon interaction and the choice of code words (1978) (28)
Crystal Structure of the Conserved Amino Terminus of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus Gripped by an Antibody (2015) (28)
Structure/Function Analysis of p55 Tumor Necrosis Factor Receptor and Fas-associated Death Domain (2000) (28)
Induction of tolerance allows separation of lethal and antitumor activities of tumor necrosis factor in mice. (1991) (27)
Tumor necrosis factor α induces early morphologic and metabolic alterations in friend leukemia cell tumors and fibrosarcomas in mice (1988) (27)
Characterization of the 5'-terminal capped structures of late simian virus 40-specific mRNA (1978) (27)
Cross-talk between steroids and NF-kappa B: what language? (1998) (26)
Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine. (1993) (26)
Nucleotide sequence of simian virus 40 Hind H restriction fragment. (1977) (26)
Functional expression of individual plasmid‐coded RNA bacteriophage MS2 genes (1982) (26)
Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses (2015) (26)
Cloning and Expression of the Canine Interferon-γ Gene (1992) (26)
External standardization in liquid scintillation counting of homogeneous samples labeled with one, two, or three isotopes (1967) (26)
A broad-host-range expression vector based on the pL promoter of coliphage lambda: regulated synthesis of human interleukin 2 in Erwinia and Serratia species (1987) (25)
High-level synthesis in Escherichia coli of the SV40 small-t antigen under control of the bacteriophage lambda pL promoter. (1982) (25)
Studies on the bacteriophage MS2. VII. Structure determination of the longer polypurine sequences present in the pancreatic ribonuclease digest of the viral RNA. (1969) (25)
TNF-R55-specific form of human tumor necrosis factor-alpha induces collagenase gene expression by human skin fibroblasts. (1995) (25)
TNF in combination with interferon-gamma is cytotoxic to normal, untransformed mouse and rat embryo fibroblast-like cells. (1989) (25)
Different preparations of natural and recombinant human interleukin-6 (IFN-beta 2, BSF-2) similarly stimulate acute phase protein synthesis and uptake of alpha-aminoisobutyric acid by cultured rat hepatocytes. (1989) (25)
Mechanism of tolerance to tumor necrosis factor: receptor-specific pathway and selectivity. (1995) (25)
Development of a simple, sensitive and specific bioassay for interleukin-1 based on the proliferation of RPMI 1788 cells. Comparison with other bioassays for IL-1. (1990) (25)
Characterization of the major altered leader sequence of late mRNA induced by SV40 deletion mutant d1-1811. (1979) (25)
Recombinant secreted haemagglutinin protects mice against a lethal challenge of influenza virus. (1993) (24)
Soluble recombinant influenza vaccines. (2001) (24)
TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways. (1998) (24)
Tumor‐selective cytotoxic effects of murine tumor necrosis factor (TNF) and interferon‐gamma (EN‐gamma) in organ culture of B16 melanoma cells and heart tissue (1988) (23)
An antibody which binds to the membrane-proximal end of influenza virus haemagglutinin (H3 subtype) inhibits the low-pH-induced conformational change and cell-cell fusion but does not neutralize virus. (1998) (23)
Purification of recombinant glycosylated human gamma interferon expressed in transformed Chinese hamster ovary cells. (1984) (23)
Hormone sensitivity in vitro and in vivo of v‐ras‐transfected mcf‐7 cell derivatives (1990) (23)
Studies on the bacteriophage MS2. IX. The heptanucleotide sequences present in the pancreatic ribonuclease digest of the viral RNA. (1971) (22)
Location of the small restriction fragments, Hind-L, Hind-M and Hpa-E, on the simian virus 40 genome. (1975) (22)
Increased stability of phage T7g10 mRNA is mediated by either a 5'- or a 3'-terminal stem-loop structure. (1996) (22)
Interferon-γ is a strong modulator of NK susceptibility and expression of β2-microglobulin but not of transferrin receptors of K562 cells (1985) (22)
Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes. (1991) (22)
Activation of the nuclear factor kappa B is not sufficient for regulation of tumor necrosis factor-induced interleukin-6 gene expression. (1993) (22)
Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma. (1997) (21)
The Oxidative Metabolism of Glutamine A MODULATOR OF REACTIVE OXYGEN INTERMEDIATE-MEDIATED CYTOTOXICITY OF TUMOR NECROSIS FACTOR IN L929 FIBROSARCOMA CELLS* (1995) (21)
The leader sequence from the 5'-terminus to the A-protein initiation codon in MS2-virus RNA. (1971) (21)
3'-Terminal nucletide sequence (n equals 361) of bacteriophage MS2 RNA. (1975) (20)
Controlling Influenza by Cytotoxic T-Cells: Calling for Help from Destroyers (2010) (20)
Polar agents with differentiation inducing capacity potentiate tumor necrosis factor‐mediated cytotoxicity in human myeloid cell lines (1995) (20)
Dimerization of chimeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: necessity for the 75 kDa-TNF receptor transmembrane domain. (1995) (20)
Effects of tumor necrosis factor on prostacyclin production and the barrier function of human endothelial cell monolayers. (1991) (20)
Expression in plants of the cloned satellite tobacco necrosis virus genome and of derived insertion mutants. (1987) (20)
A new method for partial digestion useful for sequence analysis of polynucleotides (1971) (19)
Identification of the translocatable element IS1 in a molecular chimera constructed with plasmid pBR322 DNA into which a bacteriophage MS2 DNA copy was inserted by the poly(dA).poly(dT) linker method. (1979) (19)
A bifunctional murine::human chimeric antibody with one antigen-binding arm replaced by bacterial beta-lactamase. (1994) (19)
Molecular and immunological characterization of soluble aggregated A/Victoria/3/75 (H3N2) influenza haemagglutinin expressed in insect cells (2005) (19)
Analysis of the structure-function relationship of tumour necrosis factor. Human/mouse chimeric TNF proteins: general properties and epitope analysis. (1990) (19)
Interleukin 1α acts as an autocrine growth factor for RPMI1788, an Epstein‐Barr virus‐transformed human B cell line (1988) (19)
The human fibroblast and human immune interferon genes and their expression in homologous and heterologous cells. (1982) (19)
Tumour growth results in changes in placental amino acid transport in the rat: a tumour necrosis factor alpha-mediated effect. (1996) (19)
A GFP Expressing Influenza A Virus to Report In Vivo Tropism and Protection by a Matrix Protein 2 Ectodomain-Specific Monoclonal Antibody (2015) (19)
Production of enzymatically active rat protein disulfide isomerase in Escherichia coli. (1994) (19)
Platelet-activating factor is a mediator in tumor necrosis factor/galactosamine-induced lethality. (1995) (19)
A simple apparatus for injection of nanoliter quantities into Xenopus laevis oocytes. (1981) (18)
Modulation of cellular susceptibility to the cytotoxic/cytostatic action of tumor necrosis factor by adenovirus E1 gene expression is cell type-dependent. (1990) (18)
The 5'-terminal and group of the RNA of the bacteriophage MS2. (1968) (18)
A role for interleukin 1 in the in vivo actions of tumor necrosis factor. (1989) (18)
Induction of cytolytic cells by pure recombinant human interleukin 2 (1984) (18)
Induction of Unresponsiveness to Tumor Necrosis Factor (TNF) after Autocrine TNF Expression Requires TNF Membrane Retention* (1998) (18)
Antiserum against the conserved nine amino acid N-terminal peptide of influenza A virus matrix protein 2 is not immunoprotective. (2011) (18)
Efficient specific release of periplasmic proteins from Escherichia coli using temperature induction of cloned kil gene of pMB9 (1994) (17)
Tumor necrosis factor-induced interleukin-6 expression and cytotoxicity follow a common signal transduction pathway in L929 cells. (1991) (17)
STUDIES ON POLYNUCLEOTIDES. XXII. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. A. PURIFICATION, PROPERTIES, AND SUBSTRATE SPECIFICITY. (1963) (17)
Response of murine cell lines to an IL-1/IL-2-induced factor in a rat/mouse T hybridoma (PC60): differential induction of cytokines by human IL-1 alpha and IL-1 beta and partial amino acid sequence of rat GM-CSF. (1990) (17)
The 3'-Terminal nucleotide sequence of encephalomyocarditis virus RNA. (1978) (17)
Studies on the bacteriophage MS2 6. The nucleoside 5'-triphosphate end groups of the replicative intermediate and the replicative form. (1969) (16)
Synthesis by avian-myeloblastosis-virus RNA-dependent DNA polymerase of discrete reverse transcripts of bacteriophage RNA polyadenylated in vitro. (1977) (16)
Simian virus 40 mutants carrying extensive deletions in the 72-base-pair repeat region (1983) (16)
Metabolic turnover of phosphorylation sites in simian virus 40 large T antigen (1983) (16)
Approaches to the sequence determination of SV40 DNA. (1975) (16)
TNF‐mediated IL6 gene expression and cytotoxicity are co‐inducible in TNF‐resistant L929 cells (1992) (16)
Studies on the bacteriophage MS2. Some nucleotide sequences from the RNA‐polymerase gene (1972) (16)
Characterization of the murine IL-5 receptor complex with the use of a panel of monoclonal antibodies. Relationship to the murine IL-3 receptor. (1991) (16)
Studies on the bacteriophage MS2. XVI. The termination signal of the A protein cistron. (1972) (16)
Nucleotide sequence of the restriction fragment Hind F-Eco RI2 of SV40 DNA. (1977) (16)
Studies on the bacteriophage MS2 nucleotide sequence of a 3′‐terminal fragment (n = 104) (1971) (16)
Efficient synthesis of secreted murine interleukin-2 by Saccharomyces cerevisiae: influence of 3'-untranslated regions and codon usage. (1992) (16)
Studies on bacteriophage MS2. II. Mono-, di- and trinucleotide composition of the pancreatic ribonuclease digest of MS2 RNA. (1965) (15)
Potentiation of interferon action by mixtures of recombinant DNA-derived human interferons. (1984) (15)
Different pro-inflammatory profiles of interleukin 1 (IL 1) and tumor necrosis factor (TNF) in anin vivo model of inflammation (2005) (15)
Controlled synthesis of the coat protein of satellite tobacco necrosis virus in Escherichia coli. (1984) (15)
Production of functionally active murine and murine::human chimeric F(ab')2 fragments in COS-1 cells. (1992) (15)
Bispecific T cell engaging antibody constructs targeting a universally conserved part of the viral M2 ectodomain cure and prevent influenza A virus infection (2017) (15)
Pap pili as a vector system for surface exposition of an immunoglobulin G-binding domain of protein A of Staphylococcus aureus in Escherichia coli (1993) (15)
A fairly conserved epitope on the hemagglutinin of influenza A (H3N2) virus with variable accessibility to neutralizing antibody. (1995) (15)
The tRNA pyrophosphorylase activity of Escherichia coli. A study on substrate specificity. (1970) (15)
Genes for the tumor necrosis factors a and 1 are linked to the human major histocompatibility complex (1999) (15)
High-level expression, purification, and renaturation of recombinant murine interleukin-2 from Escherichia coli. (1993) (15)
Screening of sera and tumor extracts of cancer patients using a monoclonal antibody directed against human placental alkaline phosphatase. (1985) (14)
Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride. (1991) (14)
Oral delivery of Escherichia coli persistently infected with M2e‐displaying bacteriophages partially protects against influenza A virus (2017) (14)
Modulation of expression of class II histocompatibility antigens by secretion of a cellular inhibitor in K562 leukemic cells (1987) (14)
Mechanism of induction of tolerance to tumour necrosis factor (TNF): no involvement of modulators of TNF bioavailability or receptor binding. (1994) (14)
Construction and characterization of a plasmid containing a nearly full-size DNA copy of satellite tobacco necrosis virus RNA. (1980) (14)
Studies on the bacteriophage MS2. 3. Sedimentation heterogeneity of viral RNA preparations. (1967) (14)
Transforming growth factor‐β and epidermal growth factor modulate basal and interleukin‐6‐induced amino acid uptake and acute phase protein synthesis in cultured rat hepatocytes (1990) (14)
Addition by ATP: RNA adenylyltransferase from Escherichia coli of 3'-linked oligo(A) to bacteriophage Qbeta RNA and its effect on RNA replication. (1976) (13)
Immunogenicity of Live Attenuated B. pertussis BPZE1 Producing the Universal Influenza Vaccine Candidate M2e (2013) (13)
13 Chemical Structure and Biological Activity of Bacteriophage MS2 RNA (1975) (13)
Combined treatment of colon adenocarcinoma in rats with tumor necrosis factor and the interferon inducer ABPP. (1988) (13)
Treatment of murine colitis by Lactococcus lactis secreting IL-10 (2001) (13)
Sequence of 129 nucleotides at the 3'-terminus of encephalomyocarditis virus RNA. (1978) (13)
Recognition sequence for the restriction endonuclease BglI from Bacillus globigii. (1980) (13)
The role of complement activation in tumour necrosis factor-induced lethal hepatitis. (1999) (13)
Murine IL-12 is involved in Calmette-Guérin bacillus-induced sensitization and is by itself sufficient to sensitize mice to the lethal effects of human TNF1. (1996) (13)
Isolation and characterization of IFN-gamma mRNA derived from mitogen-induced human splenocytes. (1982) (13)
Bioavailability of recombinant tumor necrosis factor determines its lethality in mice (2002) (13)
Phosphorylation patterns of tumour antigens in cells lytically infected or transformed by simian virus 40 (1981) (12)
Nucleotide sequence of the restriction fragments hind L and hind M of SV40 DNA. (1976) (12)
Involvement of IFN-gamma in Bacillus Calmette-Guérin-induced but not in tumor-induced sensitization to TNF-induced lethality. (1995) (12)
Cytotoxic activity of tumor necrosis factor is inhibited by amiloride derivatives without involvement of the Na+/H+ antiporter (1990) (12)
Studies on the bacteriophage MS2. XXIV. Hydrodynamic properties of the native and acid MS2 RNA structures (1973) (12)
The determination of ribonuclease activity. (1961) (12)
Use of the yeast three-hybrid system as a tool to study caspases. (1998) (12)
Anti‐tumor activity of tumor necrosis factor in combination with interferon‐γ is not affected by prior tolerization (1995) (12)
The occurrence of human placental alkaline phosphatase (PLAP) in extracts of normal, benign and malignant tissues of the female genital tract. (1985) (12)
Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases (1999) (12)
High-level Constitutive Expression of α1-acid Glycoprotein and Lack of Protection Against Tumor Necrosis Factor-induced Lethal Shock in Transgenic Mice (1998) (12)
Disulphide bridge formation in the periplasm of Escherichia coli: β‐lactamase::human lgG3 hinge fusions as a model system (1992) (12)
Production of interferon gamma by peripheral blood mononuclear cells from normal subjects and from patients with rheumatoid arthritis. (1988) (11)
A method for the isolation of cytidylate series from ribonuclease T1-oligonucleotides. (1975) (11)
Autocrine Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) α Differentially Modulate Cellular Sensitivity to TNF/LT-α Cytotoxicity in L929 Cells (1998) (11)
Secondary structure of the 5' end of bacteriophage MS2 RNA Methoxyamine and kethoxal modification. (1979) (11)
Human fibroblast interferon RNA transcripts of different sizes in poly(I).poly(C) induced cells. (1983) (11)
The expression of the Photinus pyralis luciferase gene in Staphylococcus aureus Cowan I allows the development of a live amplifiable tool for immunodetection (1996) (11)
Pioneering work. (1995) (11)
Inhibition of and sensitization to the lethal effects of tumor necrosis factor. (1995) (11)
Expression in non-lymphoid cells of mouse recombinant immunoglobulin directed against the tumour marker human placental alkaline phosphatase. (1988) (11)
A two-dimensional electrophoretic procedure for the separation of DNA restriction fragments. (1977) (11)
Studies on the primary structure and the replication mechanism of bacteriophage RNA. (1969) (11)
Protein kinase activities in immune complexes of simian virus 40 large T-antigen and transformation-associated cellular p53 protein (1984) (11)
Gene cloning and structure--function relationship of cytokines such as TNF and interleukins. (1987) (11)
The 3′‐terminal nucleotide sequence (n = 16) of bacteriophage MS2 RNA (1970) (10)
Circulating interferon in rabbits after simultaneous intramuscular administration of human alpha and gamma interferons. (1984) (10)
Expression, purification and crystallization of fully active, glycosylated human interleukin‐5 (1993) (10)
Interference with simian virus 40 DNA replication by adenovirus type 2 during mixed infection of monkey cells (1978) (10)
A20 inhibits NF-kappaB activation independently of binding to 14-3-3 proteins. (1997) (10)
Cyclooxygenase Inhibitors Prevent the Induction of Tolerance to the Toxic Effects of Tumor Necrosis Factor (1993) (10)
Structure-function relationship of tumour necrosis factor and its mechanism of action. (1987) (10)
Molecular and Cellular Biology of Tumor Necrosis Factor, Interferon-γ, and their Synergism (1987) (10)
Molecular variation of influenza surface antigens (1983) (10)
Specific suppression elicited by EL4 lymphoma cells in syngeneic mice. Specificity includes self‐antigens on EL4 (1987) (10)
Expression of Human and Murine Interleukins in Lactococcus lactis (1996) (10)
A radioactive assay for sialyltransferase activity using 96-well multiscreen filtration plates. (1997) (9)
Allocation of polypurine tracts to two fragments of bacteriophage MS2 RNA. (1969) (9)
Precursor structures and structure-function analysis of TNF and lymphotoxin. (1992) (9)
Studies on the bacteriophage MS2. XX. Expansion of the virion in low salt. (1972) (9)
Acquisition by the murine host of responsiveness toward various neoplastic cell lines, but not toward self, through adoptive transfer of a helper T-lymphocyte clone with antiself specificity. (1989) (9)
A simple and highly sensitive method for sequence determination of 32P-labeled oligonucleotides. (1974) (9)
Potentiation of tumour necrosis factor-mediated activities by lithium salts: a review (1992) (9)
Structure-function relationship of tumor necrosis factor and its mechanism of action (1987) (9)
An ongoing in vivo immune response affects the abundancy and differentiation of lymphokine-activated killer cell precursors, but does not influence their broad spectrum target reactivity. (1989) (9)
The sequence specificity of endonucleases CauI and CauII isolated from chloroflexus aurantiacus. (1982) (9)
Studies on bacteriophage MS2. VIII. Evidence for dimer formation of MS2 RNA by reaction with formaldehyde at acidic pH (1970) (9)
Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the late region of the genome (1979) (9)
Partial transformation of human tumor cell lines showing defective interaction between unusual p53 gene product and SV40 large-T antigen. (1990) (9)
Changes in gene expression and protein phosphorylation in murine cells, transformed or abortively infected with wild type and mutant simian virus 40. (1983) (9)
Molecular basis of a high affinity interleukin-5 receptor (1991) (9)
Coley's vaccine and TNF therapy (1992) (8)
The ribonuclease-activity of barley. (1961) (8)
Improved periplasmic production of biologically active murine interleukin-2 in Escherichia coli through a single amino acid change at the cleavage site (2006) (8)
Nucleotide sequence of the simian-virus-40 DNA region coding for the carboxyl-terminal part of the T antigen. (1978) (8)
Expression and excretion of human fibroblast beta 1 interferon in monkey cells after transfection with a recombinant SV40 plasmid vector. (1982) (8)
Recombinant interferon gamma in rheumatoid arthritis. A double-blind study comparing immuneron (recombinant interferon gamma) with placebo (1988) (8)
INITIATION OF TRANSCRIPTION BY RNA POLYMERASE II IN PERMEABLE, SV40-INFECTED OR NONINFECTED, CV1 CELLS (1981) (8)
Interleukin-6: Biological Function and Regulation of the Gene Expression in Vitro and in Vivo (1989) (8)
Species specificity and involvement of other cytokines in endotoxic shock action of recombinant tumour necrosis factor in mice (2005) (8)
Studies on the bacteriophage MS2. XXII. Conformation of MS2 RNA in acid medium (1973) (8)
Pathology of tumours produced in syngeneic Fischer rats by fibroblast-like cells before and after transfection with oncogenes. (1987) (8)
Further evidence on the role of the A protein in bacteriophage MS2 particles (1972) (8)
Comparative activity of human and murine tumor necrosis factor in toxicity and anti-infectious assays in mice. (1990) (8)
Recombinant interleukin 2 induces immunoglobulin secretion in Staphylococcus aureus Cowan strain I activated human B-cells. (1985) (7)
Studies on the bacteriophage MS2. An internal nucleotide fragment resembling some ribosomal binding sites. (1973) (7)
Two conserved tryptophan residues of tumor necrosis factor and lymphotoxin are not involved in the biological activity (1988) (7)
Effects of tumour necrosis factor on human tumour xenografts in nude mice. (2007) (7)
Cloning and expression of the canine interferon-gamma gene. (1992) (7)
Differentiation of EL4 lymphoma cells by tumoral environment is associated with inappropriate expression of the large chondroitin sulfate proteoglycan PG‐M and the tumor‐associated antigen HTgp‐175 (1998) (7)
Evaluation of recombinant A/Victoria/3/75 (H3N2) influenza neuraminidase mutants as potential broad-spectrum subunit vaccines against influenza A (1998) (7)
pH-dependent aggregation and secretion of soluble monomeric influenza hemagglutinin (2014) (7)
LamB as a carrier molecule for the functional exposition of IgG-binding domains of the Staphylococcus aureus Protein A at the surface of Escherichia coli K12 (2004) (7)
Tumor necrosis factor: a potential antitumor agent? (1987) (7)
Studies on the induction of the interleukin-6 promoter in cell lines of human and simian origin. (1994) (7)
Isolation and characterization of a specific deletion mutant of human adenovirus type 2. (1979) (7)
GAL4 is a substrate for caspases: implications for two-hybrid screening and other GAL4-based assays. (1999) (7)
Nucleotide sequence of the simian virus 40 Hind II + III restriction fragment J and the total amino acid sequence of the major structural protein VP1. (1978) (7)
Model substrates for the rapid assay of specific ribonuclease activity. (1968) (7)
Nucleotide sequence of simian virus 40 DNA: structure of the middle segment of the HindII + III restriction fragment B (sixth part of the T antigen gene) and codon usage. (2005) (7)
Expression of heterologous unfused protein in Escherichia coli. (1987) (7)
Complete nucleotide sequence of the simian-virus 40 Hind-G fragment and localisation of the carboxyl terminus of the VP1 protein. (1978) (6)
Mycoplasma in african green monkey kidney cell cultures: Biochemical detection and effects in virus-infected cells (1977) (6)
Receptor-selective mutants of tumour necrosis factor in the therapy of cancer: preclinical studies. (1994) (6)
STUDIES ON POLYNUCLEOTIDES. 23. ENZYMIC DEGRADATION. AN EXONUCLEASE FROM LACTOBACILLUS ACIDOPHILUS R26. B. STEPWISE DEGRADATION OF OLIGONUCLEOTIDES. (1963) (6)
The Invasion Suppressor Role of E-Cadherin (1992) (6)
1.4 A RESOLUTION STRUCTURE OF MOUSE TUMOR NECROSIS FACTOR, TOWARDS MODULATION OF ITS SELECTIVITY AND TRIMERISATION (1999) (6)
Nucleotide sequence of the simian virus 40 HindII + III restriction fragment A (second part of the T antigen gene). (2005) (6)
Use of the phage lambda PL promoter for high-level expression of human interferons in Escherichia coli. (1986) (6)
Nucleotide sequence of the simian virus 40 Hind-K restriction fragment. (1978) (6)
Studies on the bacteriophage MS2. XLI. Nature of the azure mutation. (1980) (6)
TNF: its potential as an antitumour agent. (1988) (6)
Detection of uridine 3'-ethyl phosphate and homologues in digests of ribonucleic acid hydrolyzed with pancreatic ribonuclease in the presence of traces of ethanol. (1966) (6)
Nucleotide sequence of part of the simian virus 40 Hind-D restriction fragment. The presumed initiation region of the VP2 gene. (1978) (6)
Nucleotide sequence of the simian virus 40 HindII + III restriction fragment D and the total amino acid sequence of the late proteins VP2 and VP3. (1978) (6)
Structure of the components of the adenovirus-simian virus 40 hybrid population Ad2++HEY and reciprocal molecular interactions. (1978) (6)
Studies on the inducibility of the IL6 promoter using a reporter gene construction. (1993) (6)
On the possible modulating role of the isoleucine AUA-codon in bacteriophage MS2 RNA. (1976) (6)
Asymmetric linker molecules for recombinant DNA constructions. (1979) (6)
Purification of human interleukin-4 produced in Escherichia coli. (1989) (6)
Cloning and structure of a mouse interleukin-2 chromosomal gene (2004) (6)
Oxygen radicals as second messengers. (1991) (5)
Expression of cell surface glycoproteins in tumour invasion in vitro (1986) (5)
Deoxynucleotide substitution: a new technique for sequence analysis of RNA. (1974) (5)
Induction of 26kDa Protein mRNA in Human Cells Treated with Recombinant Human Tumour Necrosis Factor (rTNF) (1987) (5)
Amino acid sequence analysis of a mouse interleukin 5 receptor protein reveals homology with a mouse interleukin 3 receptor protein (1991) (5)
Correlation between temperature-dependent cytoplasmic solubility and periplasmic export of a heterologous protein in Escherichia coli. (1989) (5)
Human interferon-beta, expressed in Saccharomyces cerevisiae, is predominantly directed to the vacuoles. Influence of modified co-expression of secretion factors and chaperones. (1994) (5)
Increased IL-6 production and IL-6-mediated Ig secretion in murine host-vs-graft disease. (1993) (5)
Strategies to Broaden the Therapeutic Margin of Tumor Necrosis Factor1 (1993) (5)
Phenotypic effects in Saccharomyces cerevisiae after regulated expression of beta-(1,3)-glucanase from Nicotiana plumbaginifolia. (1993) (5)
Tumor Necrosis Factor Cytotoxicity is Associated with Activation of Cellular Phospholipases (1993) (5)
In vitro and in vivo Action of Tumor Necrosis Factor1 (1990) (5)
II. Yeast sequencing reports. The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp70 stress protein genes SSA3 and SSA4 (1994) (5)
Crystallization of bacteriophage MS2. (1979) (5)
Catabolism of nucleosides by barley-extracts. (1960) (5)
The complex effects of recombinant tumour necrosis factor-alpha (rhTNF-alpha) in human ovarian cancer xenograft models. (1990) (5)
In vitro cotranslational processing of human pre-interferon beta 1 enhances its biological activity. (1982) (4)
Rhythmic Genetic Code of Ribonucleic Acid Bacteriophages (1966) (4)
The presence of homologous regions between interferon sequences (1984) (4)
Tumour necrosis factor (1991) (4)
Treatment of murine interferon-α/β-sensitive and -resistant Friend leukemia cells with tumor necrosis factor in combination with murine interferon-α/β or -γ (1986) (4)
Effect of oncogene transfection or passage in vivo on malignant phenotypes of rat2 cells. (1989) (4)
Production in Escherichia coli of a functional murine and murine::human chimeric F(ab')2 fragment and mature antibody directed against human placental alkaline phosphatase. (1995) (4)
3'-Terminal nucleotide sequence (N = 41) of satellite tobacco necrosis virus RNA. (1979) (4)
Studies on the bacteriophage MS2. XXIII. Fixation of the MS2 RNA acid structure by formaldehyde (1973) (4)
Nucleotide sequence of the restriction fragment Hind-F-EcoRI1 of simian-virus-40 DNA (part of the VP1 gene). (1978) (4)
Two dimensional electrophoretic separation of restriction fragments. (1977) (3)
Tumour necrosis factor: mechanism of action at the molecular, cellular and in vivo level. (1992) (3)
TNF-induced mechanisms for IL6 gene induction (1995) (3)
Expression of functional mouse antibodies directed against the tumour marker human placental alkaline phosphatase in non‐lymphoid cells (1988) (3)
Studies on the bacteriophage MS 2 (2004) (3)
The reaction mechanism of a nucleoside phosphorylase. (1962) (3)
Alloinduced suppression and cytotoxicity: two functions of a single cell. (1987) (3)
Nucleotide sequence of the Hind-I-proximal part of simian virus 40 HindII + III restriction fragment B (fifth part of the T antigen gene). (2005) (3)
Bacteriophage MS2 RNA andEscherichia coli 23 S ribosomal RNA have a similar conformation after reaction with formaldehyde at low pH (1972) (3)
Nuclear Magnetic Resonance Analysis of Tumor Necrosis Factor-induced Alterations of Phospholipid Metabolites and pH in Friend Leukemia Cell Tumors and Fibrosarcomas in Mice 1 (2006) (3)
A host factor required for Q-beta-RNA-replication in "Escherichia coli". (1973) (3)
The distribution of tetranucleotides present in the pancreatic ribonuclease digests of bacteriophage MS2 RNA and yeast RNA. (1966) (3)
48 Induction of u-PA antigen and mRNA in human endothelial cells by inflammatory mediators (1988) (3)
Therapeutic potential of tumor necrosis factor-alpha and gamma-interferon in experimental human ovarian cancer. (1987) (3)
Cloning and expression of cytokine genes (1995) (3)
Satellite tobacco necrosis virus: a new vector in plant genetic engineering (1986) (3)
Specific dimer formation of ribosomal RNA and of viral RNA in the presence of formaldehyde (1970) (3)
Isolation and characterization of a human fibroblast interferon gene and its expression in Escherichia coli. (1981) (3)
Sequence determination of Gp‐rich oligonucleotides by means of the kethoxal modification (1976) (3)
Tumorigenicity, invasiveness and metastatic capability of FR3T3 rat cells before and after transfection with bovine papilloma virus type 1 DNA (2005) (3)
Transforming growth factor-beta and epidermal growth factor modulate basal and interleukin-6-induced amino acid uptake and acute phase protein synthesis in cultured rat hepatocytes. (1990) (2)
Cutting Edge Approaches Toward Novel and Cross-Protective Influenza Vaccines (2012) (2)
Spontaneous and oncogene-mediated acquisition of the invasive phenotype by cells in culture. (2002) (2)
A universal vaccine against influenza. (2006) (2)
Slippage of DNA polymerase I during synthesis of ds-cDNA. (1988) (2)
Natural killer cell response to interferons. (1986) (2)
Interferon-gamma is a strong modulator of NK susceptibility and expression of beta 2-microglobulin but not of transferrin receptors of K562 cells. (1985) (2)
Resistance to tumor necrosis factor (TNF) cytotoxicity by autocrine TNF production is independent of intracellular signaling pathways (1997) (2)
Simultaneous light emission from cloned Vibrio fischeri lux genes and expression of LamB or LamB–protein A fusion proteins in Escherichia coli depends on using a single chimeric operon (1995) (2)
Induction of urokinasetype plasminogen activator in human endothelial cells by inflammatory mediators (1989) (2)
Synergy between interferon and tumor-necrosis-factor - mechanism of action (1987) (2)
Rhythmic variations in purine run frequencies in bacteriophage RNA. (1976) (2)
Expression in Escherichia coli of the death domain of the human p55 tumor necrosis factor receptor. (2001) (2)
Interleukin 1 alpha acts as an autocrine growth factor for RPMI 1788, an Epstein-Barr virus-transformed human B cell line. (1988) (2)
The chromatography of barley ribonuclease (1962) (2)
Tumour Necrosis Factor and Interleukin-6: Structure and Mechanism of Action of the Molecular, Cellular and in Vivo Level (1989) (2)
CHAPTER 14 – The Structure of Viral RNA (1973) (2)
Studies on the bacteriophage MS2. IV. The 3'-OH terminal undecanucleotide sequence of the viral RNA chain. (1967) (2)
Autocrine Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) (cid:97) Differentially Modulate Cellular Sensitivity to TNF/LT- (cid:97) Cytotoxicity in L929 Cells (1998) (2)
The 5'-terminal tetranucleotide sequence of bacteriophage MS2 ribonucleic acid. (1968) (1)
Engineering of the carbohydrate moiety of fungal proteins to a mammalian type (1998) (1)
An advanced vector system for high-level recombinant gene expression in Escherichia coli (1999) (1)
Expression of the murine interleukin-5 receptor on Xenopus laevis oocytes. (1990) (1)
Mechanisms of tumor necrosis factor dependent antigen induction in vascular endothelium (1986) (1)
Regulation of expression of a cistron in the RNA bacteriophage MS2. (1974) (1)
Proceedings: Chemical modification of some hairpin loops of the MS2 genome with the methoxyamine reagent. (1976) (1)
Crystallization and preliminary X-ray studies of mouse tumor necrosis factor. (1997) (1)
TNF-induced, cytotoxicity-linked IL6 gene expression in L929 cells may require factors other than NF-kappa B. (1992) (1)
IL-4 acts synergistically on the IL-2 response of an autoreactive T-cell clone; synergism correlates with increased intracellular IL-2, but not with a modified IL-2 receptor expression. (1990) (1)
A new method for purification of influenza neuraminidase released by pronase digestion. (1993) (1)
Studies on the bacteriophage MS 2. XVII. Suppressor-sensitive mutants of the A protein cistron. (1972) (1)
Limited enzymatic degradation of bacteriophage MS2 RNA. (1968) (1)
Animals and Medicines (1986) (1)
Abnormal glutathione sulfate levels after interleukin 6 treatment tumor-induced cachexia (1996) (1)
The Chromatographic Separation of Mixtures of Diglyceromonophosphoric Acids and Related Products (2010) (1)
INHIBITION OF TUMOR NECROSIS FACTOR‐INDUCED LIVER TOXICITY AND LETHALITY BY THE ACUTE PHASE PROTEINS &agr;‐1‐ACID GLYCOPROTEIN AND &agr;‐1‐ANTITRYPSIN.: 256 (1997) (1)
Sequences at the 5'-terminus of bacteriophage Q-beta-RNA. (1969) (1)
Three-dimensional structure of the extracellular domain of Matrix protein 2 of influenza A virus (2014) (1)
Nucleotide sequence of the SV40 DNA restriction fragment Hind C-Hap 2. (1977) (1)
A micro-method for the determination of ribonuclease activity. (1960) (1)
Can antiviral drug-resistant chikungunya viruses be transmitted by mosquitoes ? (2016) (1)
DRIFT AND SHIFT OF INFLUENZA VIRUS STUDIED AT THE GENOMIC LEVEL (1981) (1)
3 '-Terminal nucleotide sequence ( n = 361 ) of bacteriophage MS 2 RNA ( viral RNA polymerase / termination signals / untranslated RNA ) (2003) (1)
Nature of the acid phosphatase present in scales of human skin. (1960) (1)
The human fibroblast interferon gene(s) and their expression in heterologous cells. (1982) (1)
Cloning and expression of human interferon-beta: from bc to ac. (2009) (1)
Deletion mapping of the inducible promoter of human IFN-beta gene. (1983) (1)
Oligonucleotide directed mutagenesis: Selection of mutants by hemimethylation of GATC-sequences (2004) (1)
Differential role of calcium in TNF-mediated apoptosis and GM-CSF secretion in a T cell hybridoma (1997) (1)
Characterization of the interaction between murine tumour necrosis factor and monoclonal antibodies. (2002) (1)
The receptor for human interleukin-5 (1991) (0)
The use of interleukin-15 (1998) (0)
Proceedings: Bacteriophage ms2 rna: nucleotide sequence determination of the A protein gene. (1974) (0)
Construction of a mouse and a mouse-human chimeric immunotoxin on the genetic level and production of functional protein in E. coli (1993) (0)
The factor-dependence of bacteriophage Q-beta RNA-polymerase. (1969) (0)
[Micromethod for the determination of ribonuclease activity & its application in the amoeba Chaos chaos]. (1958) (0)
Ser thr protein-kinases involved in mitogenic, cytotoxic or chemotactic signaling pathways (1993) (0)
[Double-stranded RNA from "Escherichia coli" infected with the bacteriophage MS2: the parental RNA-labelled replicative forms and properties of an infectious RNA-containing structure]. (1967) (0)
Trispecific Antibody Derivatives Production of Recombinant Bispecific and Heterodimerization Scaffold for the Fab Chains As an Efficient (2000) (0)
The heptanucleotide sequences present in the pancreatic ribonuclease digest of bacteriophage MS2 RNA. (1970) (0)
Interferon and inducers: Tumor necrosis factor and interferon-γ : strong synergism in the human and murine system (1985) (0)
The molecular weight of a fast sedimenting MS2 RNA form (1972) (0)
Two Pathways of Tumor Necrosis Factor Signal Transduction: In vitro and in vivo Implications (1993) (0)
T Cell Responsiveness to Antigen + Activities of IL-15 Enhance Secondary CD 4 Quiescence-Inducing and Antiapoptotic (1998) (0)
Host factor dependent and factor-free polyribonucleic acid synthesizing activities of the bacteriophage Q RNA replication enzyme. (1971) (0)
Plasmid vectors, processes for their preparation and process for preparing the polypeptide (1981) (0)
Toxic Effects ofRecombinant Tumor Necrosis Factor in Suckling Mice (2007) (0)
ENGINEERING OF THE CARBOHYDRATE MOIETY OF FUNGAL GLYCOPROTEINS TO A MAMMALIAN TYPE. (1995) (0)
Process for the preparation of recombinant alpha chains of human interleukin 5 receptor and pharmaceutical compositions containing them (1991) (0)
Position of the first initiation codon in the RNA of bacteriophages MS2 and R17. (1971) (0)
Foerfarandena Foer framstaellning of polypeptidhomologer of tumoernekrosisfaktorer with stor yield. (1985) (0)
Genetic manipulations derived from RNA viruses containing recombinant DNA sequences (1990) (0)
Methoxyamine and Kethoxal Modification (1979) (0)
Synthesis of a tumorspecific single-chain antibody and derivatives in E. coli and COS-1 cells (1997) (0)
Role of the signal peptide in the trans-membrane transport of PBR322 coded β-lactamase (1981) (0)
T7-RNA-polymerase terminates at poly-A regions on plasmids. (1993) (0)
The Future Role in Medicine of Proteins Made by Genetic Engineering (1986) (0)
11 – Role of Reactive Oxygen Species in Tumor Necrosis Factor Toxicity (2000) (0)
The β-lactamase gene of PBR322 is transcribed from two different promoters (1981) (0)
Nucleic Acids Research (2010) (0)
Complex of Influenza M2e and Antibody (2015) (0)
Increase in production of tumor necrosis factor (1995) (0)
A monoclonal antibody reactive with a tumor antigen that is expressed upon tumor progression (1997) (0)
[Column chromatography of barley ribonuclease]. (1959) (0)
Foerbaettrade vektorer foerfaranden Foer framstaellning from these two vektorer Science Foer expression of klonade gener (1981) (0)
Diversity of 5'-termini in mRNA of SV40 deletion mutant dl-1811 [proceedings]. (1979) (0)
[The purification and the characterization of an exonuclease of Lactobacillus acidophilus R 26]. (1963) (0)
Combinations of necrosis-tumor-factors and entzuendungshemmenden agents for the treatment of malignant and non-malignant diseases. (1987) (0)
Nucleotide sequence of the simian virus 40 HindII + III restriction fragment I (fourth part of the T antigen gene). (1980) (0)
DNA sequence encoding the receptor alpha chain of human interleukin 5. (1991) (0)
Cytokine research in Belgium. (2011) (0)
influenza antigen immune Protective and its use for vaccination (1998) (0)
The thermal inactivation of barley ribonuclease. (1961) (0)
Mediate Protection Receptors and Alveolar Macrophages Matrix Protein 2 of Influenza A: Fc Universal Vaccine Based on Ectodomain of (2010) (0)
Chemical evidence for the exclusive occurrence of pppGp nucleoside tetraphosphate in the alkaline hydrolysates of MS2 replicative form and replicative intermediate: implications for the structure of the replicative intermediates and for the mechanism of viral RNA replication. (1968) (0)
SYMPOSIUM ‐ RECEPTOR ASSOCIATED PROTEINS AND INTRACELLULAR SIGNALLING ‐ CELL DEATH. (2000) (0)
Structural studies on the SV40 DNA genome [proceedings]. (1977) (0)
Expression of E-cadherin in eptthelial tumor cells abrogates malignant invasion (1990) (0)
Optimalization and application in TNF-related models of a method to estimate NO production in vivo. (1995) (0)
The 5'-terminal end group of the ribonucleic acid of the bacteriophage MS2. (1968) (0)
Infection-permissive immunity provided by NA- and M2e-based vaccines protects against influenza A virus challenge and allows the induction of heterosubtypic immunity during subsequent infections. (VAC5P.1127) (2015) (0)
Structure and function of the bacteriophage MS2 RNA (1973) (0)
EXPRESSION OF HUMAN FIBROBLAST AND HUMAN IMMUNE INTERFERON GENES IN HOMOLOGOUS AND HETEROLOGOUS CELLS (1982) (0)
The generation of mitochondrial oxygen radicals as a crucial step in the cytotoxic action of TNF (1991) (0)
Using a Lactococcus producing cytokines to treat colitis. (1999) (0)
Preliminary studies on tumor necrosis factor (TNF) (1987) (0)
Protection against Tumor Necrosis Factor-Induced Lethality1 (1993) (0)
Tumor necrosis factor: mechanisms of action and therapeutic possibilities (1995) (0)
Increase of the soluble fraction of human interferon-y expressed in Escherichia coli, due to the chaperonin activity of GroEL/ES. (1993) (0)
EXTERNAL STANDARDIZATION IN HOMOGENEOUS LIQUID SCINTILLATION COUNTING OF $sup 3$H, $sup 14$C, AND $sup 32$P, SINGLY OR IN COMBINATION. (1966) (0)
The effect of salt concentration on the polyribonucleotide synthesizing activities in extracts of uninfected and RNA-bacteriophage infected "Escherichia coli". (1970) (0)
Cloning and Expression of a Fused Gene Encoding TNFRI Death Domain and Chloramphenicol Acetyltransferase. (1998) (0)
Future prospects and problems. (1989) (0)
Interference withSimian Virus 40DNA Replication by Adenovirus Type2During MixedInfection ofMonkeyCells (1978) (0)
Metabolic Turnover ofPhosphorylation Sites inSimian Virus 40LargeTAntigen (1983) (0)
Crystal structure of mTNF (1996) (0)
The purine sequences of yeast ribonucleic acid. (1964) (0)
Immunoprotective antigen flu and its use in vaccination. (1998) (0)
Vivo Invasiveness Correlates with Reduced Tumorigenicity and Reduced Expression of the Tumor Necrosis Factor Gene in Tumor Cells (2006) (0)
Proceedings: Information content of an RNA genome. (1974) (0)
Improved escherichia coli host cell (1995) (0)
Tumor Necrosis Factor-Induced Gene Expression and Cytotoxicity Share a Signal Transduction Pathway (1991) (0)
Tumor Necrosis Factor: Mechanism of Action and its Potential for Anticancer Therapy (1992) (0)
Antibody Derivatives multi-purpose (1999) (0)
[Cancer: what does the future bring?]. (2001) (0)
Tumor necrosis factor: Mechanisms of action and potential role in cancer treatment (1993) (0)
[A micromethod for the determination of ribonuclease and its applications]. (1963) (0)
Molecular biology approaches to cancer and to cancer therapy. (1991) (0)
ID: 208: Comparison of the antiviral activity of Mus spretus Mx1 and Mus musculus A2G Mx1 against influenza A viruses (2015) (0)
Bacteriophage MS2 induced proteins. (1968) (0)
370 Determination of human placental alkaline phosphatase (hPLAP) in sera and tumor extracts of cancer patients using an anti-hPLAP monoclonal antibody (1983) (0)
Structural studies on sv40 dna genome (1977) (0)
Tumour necrosis factor: intracellular mechanism of action (1997) (0)
The separation of mono-, di- and trinucleotide sequences from the pancreatic ribonuclease digest of the ribonucleic acid of the bacteriophage MS2. (1965) (0)
Mapping of polypurine sequences in bacteriophage MS2 RNA. (1969) (0)
[Comparison of the phosphatase activity of the psoriasic epidermis and squamae]. (1959) (0)
Preparation of recombinant dna molecule (1995) (0)
Treatment of murine interferon-alpha/beta-sensitive and -resistant friend leukemia cells with tumor necrosis factor in combination with murine interferon-alpha/beta or -gamma. (1986) (0)
Synthesis of discrete reverse transcripts of polyadenylated phage RNA. (1976) (0)
Control of release of periplasm protein into culture medium (1989) (0)
CRYSTALLOGRAPHY OF BIOLOGICAL MACROMOLECULES (2005) (0)
Synthesis of a poly(A)-segment, covalently linked to the 3'-end of bacteriophage MS2 RNA. (1974) (0)
Proceedings: Nucleotide sequence analysis of the SV40 - hind H DNA fragment. (1974) (0)
[26] Expression of heterologous unfused protein in Escherichia coli (1987) (0)
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences: 356 (1416) (2001) (0)
TNF Cdc 42-Mediated Filopodium Formation by in Macrophages : Inhibition of Regulate TNF-Induced Actin Reorganization Multiple Signal Transduction Pathways and (1998) (0)
Mechanisms of Anticancer Action of Interferons on Human Tumour Xenografts in Nude Mice (1987) (0)
Dna coding alpha-chain or its part, particularly shil5r alpha of human interleukin receptor, vector containing the same, host cell transformed with the vector and its production and use (1991) (0)
Tailoring of an Anti-Human Placental Alkaline Phosphatase Immunoglobulin Using Genetic Engineering (1989) (0)
Translational coupling: the importance of the translational efficiency of the first cistron. (1993) (0)
Functional exposition of streptavidin at the surface of Escherichia coli using the IgAß domain of the IgA protease of Neisseria gonorrhoea. (1993) (0)
External standardization in homogeneous liquid scintillation counting of H3, C14, and P32, singly or in combination. (1966) (0)
HIGH LEVEL SYNTHESIS OF PROTEINS IN HETEROLOGOUS CELLS USING GENETIC ENGINEERING APPROACHES (1984) (0)
Nucleic Acids Research (2012) (0)
Similarities and Dissimilarities in the Effects of Tumor Necrosis Factor and Interferon-α/β on Transplantable Tumors and on Suckling Mice (1988) (0)
B cellgrowth modulating anddifferentiating activity of recombinant human26-kdprotein (BSF-2, HuIFN-02, HPGE) (1987) (0)
A method of producing human interleukin-5 receptor (1991) (0)
IL-2 discriminates between activation-induced cell death and anergy induction in CD4+ T lymphocytes (1997) (0)
Mechanisms of sensitization by infections towards tumour necrosis factor induced sirs (2005) (0)
The choice of code words in phage MS2 RNA. (1973) (0)
Inhibiteurs de l'activation de nf-kb (1999) (0)
The distribution of purine sequences in the ribonucleic acid of the bacteriophage MS2. (1965) (0)
Title Page / Contents / Acknowledgements / Preface (1993) (0)
Induction of HLA class II antigens by IFN-gamma on K562 cells depends on the production of a specific inhibitor and on the acquisition of a differentiated phenotype (1988) (0)
Viral RNA polymerase levels induced in non-permissive "escherichia coli" cells by suppressor-sensitive mutants of bacteriophage MS2. (1967) (0)
H.Feldmann 1,2, M.Aigle3, G.Aljinovic4, B.Andre5, M.C.Baclet3, C.Barthe3, A.Baur6, A.-M.Becam7, N.Biteau3, E.Boles6, T.Brandt8, M.BrendeI9, M.Brückner10, F.Bussereau11, C.Christiansen8, R.Contreras12, M.Crouzet3, C.Cziepluch13, N.Demolis11, Th.Delaveau14, F.Doignon3, H.Domdey15, S.Düsterhus16, E.D (2004) (0)
Recombinant dna containing sequence derived from rnatype virus and genetic manipulation using the dna (1990) (0)
SENSITIZATION TO AND INHIBITION OF THE LETHAL EFFECTS OF TNF IN INFECTED MICE: 328 (1997) (0)
Characterization of the sequence next to the 3-terminal poly-(A) of encephalomyocarditis virus RNA [proceedings]. (1977) (0)
Selected talk 2 MCMV exploits the spleen as a transfer hub for systemic dissemination upon oronasal inoculation (2015) (0)
Improved vectors, methods for making such vectors and expression of cloned genes. (1981) (0)
A novel human Respiratory Syncytial Virus vaccine based on the extracellular domain of the Small Hydrophobic protein (2012) (0)
Virus-specific RNA synthesis in bacteriophage MS2-infected "Escherichia coli". (1971) (0)
The Structure of the DNA of Bacteriophage cf » X 174 m . Ultracentrifugal Evidence for a Ring Structure (2009) (0)
The base sequence at the 5'-terminus of bacteriophage Q-beta RNA. (1969) (0)
Protein Kinase Activities inImmuneComplexes ofSimianVirus40 LargeT-Antigen andTransformation-Associated Cellular p53Protein (1984) (0)
Late abstracts 186–187 (2005) (0)
Nouvel homologue de caspase (1999) (0)
Production of enzymatically active rat protein disulfide isomerase in COS-1 cells. (1993) (0)
A new method for sequence analysis of plant virus RNA [on Satellite Tobacco Necrosis Virus]. (1977) (0)
Effect of TNF-α on Human Ovarian Cancer Xenografts in Nude Mice (1988) (0)
Sensitization of T \ imor Cells to l \ imor Necrosis Factor Action by the Protein Kinase Inhibitor Staurosporine 1 (2006) (0)
The application of a monoclonal antibody for the detection of human placental alkaline phosphatase in sera and tumor extracts of cancer patients. (1984) (0)
TNF-gene expression confers TNF-resistance (1990) (0)
Role of FADD and Caspase family members in TNF-induced apoptosis in a T cell hybridoma (1997) (0)
Nucleotide sequence of the 3'-end of MS2 RNA. (1973) (0)
Interferon and Tumor Necrosis Factor Alter the Phospholipid Metabolism in Friend Leukemia Cell Tumors in Mice (1987) (0)
Proceedings: Studies on the excision process of SV40-DNA during infection with Adeno-SV40-hybrid Ad.2++ HEY. (1976) (0)
Use of a cytokine-producing Lactococcus strain for the treatment of colitis (1999) (0)
Reaction of formaldehyde with viral MS2-RNA at low pH. (1970) (0)
X-ray structure of the (Ala-84→Val] mutant of human tumor necrosis factor (1993) (0)
Monoclonal antibodies as a tool in the detection of human placental alkaline phosphatase. (1984) (0)

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