Barbara McClintock
American scientist and cytogeneticist
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Biology
Barbara McClintock's Degrees
- PhD Botany Cornell University
Why Is Barbara McClintock Influential?
(Suggest an Edit or Addition)According to Wikipedia, Barbara McClintock was an American scientist and cytogeneticist who was awarded the 1983 Nobel Prize in Physiology or Medicine. McClintock received her PhD in botany from Cornell University in 1927. There she started her career as the leader of the development of maize cytogenetics, the focus of her research for the rest of her life. From the late 1920s, McClintock studied chromosomes and how they change during reproduction in maize. She developed the technique for visualizing maize chromosomes and used microscopic analysis to demonstrate many fundamental genetic ideas. One of those ideas was the notion of genetic recombination by crossing-over during meiosis—a mechanism by which chromosomes exchange information. She produced the first genetic map for maize, linking regions of the chromosome to physical traits. She demonstrated the role of the telomere and centromere, regions of the chromosome that are important in the conservation of genetic information. She was recognized as among the best in the field, awarded prestigious fellowships, and elected a member of the National Academy of Sciences in 1944.
Barbara McClintock's Published Works
Published Works
- The significance of responses of the genome to challenge. (1984) (2297)
- The Stability of Broken Ends of Chromosomes in Zea Mays. (1941) (1499)
- The origin and behavior of mutable loci in maize (1950) (1427)
- Chromosome organization and genic expression. (1951) (1159)
- Controlling elements and the gene. (1956) (712)
- The Behavior in Successive Nuclear Divisions of a Chromosome Broken at Meiosis. (1939) (548)
- Mutable Loci in Maize (1951) (514)
- The Production of Homozygous Deficient Tissues with Mutant Characteristics by Means of the Aberrant Mitotic Behavior of Ring-Shaped Chromosomes. (1938) (449)
- The Fusion of Broken Ends of Chromosomes Following Nuclear Fusion. (1942) (300)
- The control of gene action in maize (1965) (278)
- A Correlation of Cytological and Genetical Crossing-Over in Zea Mays. (1931) (253)
- Induction of Instability at Selected Loci in Maize. (1953) (239)
- Neurospora. I. Preliminary observations of the chromosomes of Neurospora crassa (1945) (226)
- A Cytological and Genetical Study of Triploid Maize. (1929) (199)
- Cytological observations of deficiencies involving known genes, translocations and an inversion in Zea mays (1931) (196)
- Mechanisms that rapidly reorganize the genome (1978) (192)
- The association of non-homologous parts of chromosomes in the mid-prophase of meiosis in zea mays (1933) (188)
- Cytogenetic Studies of Maize and Neurospora (1945) (183)
- The fusion of broken ends of sister half-chromatids following chromatid breakage at meiotic anaphases (1938) (174)
- CHROMOSOME MORPHOLOGY IN ZEA MAYS. (1929) (166)
- Some Parallels Between Gene Control Systems in Maize and in Bacteria (1961) (164)
- A Correlation of Ring-Shaped Chromosomes with Variegation in Zea Mays. (1932) (153)
- A CYTOLOGICAL DEMONSTRATION OF THE LOCATION OF AN INTERCHANGE BETWEEN TWO NON-HOMOLOGOUS CHROMOSOMES OF ZEA MAYS. (1930) (152)
- The Suppressor-Mutator System of Control of Gene Action in Maize (1958) (130)
- Mutations in Maize and Chromosomal Aberrations in Neurospora (1954) (127)
- A Method for Making Aceto-Carmin Smears Permanent (1929) (120)
- Intranuclear systems controlling gene action and mutation. (1956) (113)
- The Relation of Homozygous Deficiencies to Mutations and Allelic Series in Maize. (1944) (112)
- Mutation in maize (1956) (110)
- Aspects of gene regulation in maize (1964) (103)
- SPONTANEOUS ALTERATIONS IN CHROMOSOME SIZE AND FORM IN ZEA MAYS (1941) (100)
- Maize genetics. (1946) (94)
- Topographical relations between elements of control systems in maize (1962) (94)
- Further Studies of Gene-Control Systems in Maize (1963) (87)
- Controlled mutation in maize (1955) (83)
- Components of action of the regulators Spm and Ac (1965) (79)
- Genetic and cytological studies of maize (1959) (75)
- Chromosome constitution of races of maize. Its significance in the interpretation of relationships between races and varieties in the Americas (1981) (71)
- The Cytological Identification of the Chromosome Associated with the R-G Linkage Group in ZEA MAYS. (1931) (68)
- A GENIC DISTURBANCE OF MEIOSIS IN ZEA MAYS. (1928) (63)
- Genetic systems regulating gene expression during development (1968) (63)
- Development of the maize endosperm as revealed by clones (1978) (60)
- The Association of Mutants with Homozygous Deficiencies in Zea Mays. (1940) (56)
- The Order of the Genes C, Sh and Wx in Zea Mays with Reference to a Cytologically Known Point in the Chromosome. (1931) (53)
- The Contribution of One Component of a Control System to Versatility of Gene Expression (1971) (53)
- The cytogenetics of maize (1935) (48)
- Regulation of pattern of gene expression by controlling elements in maize. (1966) (45)
- Chromosome Constitutions of Mexican and Guatemalan Races of Maize (1960) (37)
- The states of a gene locus in maize (1967) (36)
- Artefacts created during oral biopsy procedures. (1987) (34)
- Polyploidy in Zea Mays L. (1926) (34)
- Significance of chromosome constitutions in tracing the origin and migration of races of maize in the Americas (1978) (31)
- A 2n-1 chromosomal chimera in maize (1929) (23)
- Modified gene expressions induced by transposable elements (1980) (14)
- The Correlation of Cytological and Genetical Crossing-Over in Zea Mays. A Corroboration. (1935) (14)
- Ichthyodeterrent Properties of Lipophilic Extracts from Bermudian Sponges (1997) (12)
- Restoration of A1 gene action by crossing over (1965) (9)
- Mechanisms that rapidly reorganize the genome : (genome reorganizations, transposable gene control systems, restriction enzymes, stabilizing mechanisms) (1978) (8)
- The production of maize plants mosaic for homozygous deficiencies: Simulation of the bm1 phenotype through loss of the Bm1 locus (1937) (4)
- A Method for Detecting Potential Mutations of a Specific Chromosomal Region (1938) (3)
- California Institute of Technology Lectures (1954) (3)
- Chromosome Organization and Function in Higher Organisms (1964) (3)
- Trauma as a Means of Initiating Change in Genome Organization and Expression (1983) (3)
- A Case of Ac-induced Instability at the Bronze Locus in Chromosome 9 (1955) (2)
- Genome Shock as a Means of Reprogramming Genomes (1983) (2)
- Breakage-fusion-bridge cycle induced deficiencies in the short arm of chromosome 9 (1944) (2)
- Attempts to Separate Ds from neighboring gene loci (1965) (2)
- Continued Study of a Structurally Modified Chromosome 9 (1957) (2)
- Transposition sequences of Ac (1955) (1)
- System responsible for mutations at a1m-2 (1955) (1)
- Studies of instability of chromosome behavior of components of a modified chromosome 9 (1956) (1)
- Columbia University Lectures (1964) (1)
- Spread of Mutational Change Along the Chromosome (1955) (1)
- The Cytological Identification of the Chromosomes Associated with the 'R-golden' and 'B-liguleless' Linkage Groups in Zea Mays (1)
- A Genic Disturbance of Meiosis in Zea mays (1928) (1)
- Continued Study of Stability of Location of Spm (1957) (1)
- Letter from Barbara McClintock to Curt and Evelyn Stern (1934) (0)
- "The Ds Locus. Part III. Transposition of the Ds Locus" (pages 51-77) (1949) (0)
- Memorandum from Barbara McClintock to William L. Brown (1962) (0)
- The Genetic Location and Cytological Behavior of Ds (1954) (0)
- The sixth volume of Essays of an Information Scientist contained all of my essays published during the previous year in Current Contents (1998) (0)
- A suppressor-mutator system of control of genic action and mutational change (1955) (0)
- Letter from Barbara McClintock to J. R. S. Fincham (1973) (0)
- The Breakage-fusion-bridge Cycle and the Origin of Instability at Gene Loci (1954) (0)
- Letter from Barbara McClintock to Curt Stern (1933) (0)
- "Memorandum to Marcus Rhoades (about the Ds Locus)" [pages 26-54] (1949) (0)
- Spread of Mutation Change Along Chromosome. The a1 m-1; a1 m-2 Control Systems (1954) (0)
- How Chromosomes Have Been Used to Trace the Origin and Migration of Races of Maize in the Americas (1980) (0)
- BOTANY: CREIGHTON A ND McCLINTOCK hoc. N. A. S. THE CORRELATION OF CYTOLOGICAL AND GENETICAL CROSSING-OVER IN ZEA MA YS. A CORROBORATION (2001) (0)
- ASPECTS OF GEKE REGULATIOK IN MAIZE (2001) (0)
- Further study of Ac control of mutation at the bronze locus in chromosome 9 (1956) (0)
- Letter from Barbara McClintock to Peter A. Peterson (1972) (0)
- Letter from Barbara McClintock to Angel Kato (1964) (0)
- Lecture Notes on Maize (1986) (0)
- The Discovery of Ds. Its Behavior and its Relation to Mutable Loci (1954) (0)
- Letter from Barbara McClintock to Joshua Lederberg (1948) (0)
- MUTABLE LOCI IN (2001) (0)
- Aspects of Gene Control in Higher Organisms (1965) (0)
- BARBARA McCLINTOCK : STATEMENT OF ACHIEVDlENTS Resume (1999) (0)
- THE ORDER OF THE GENES C, Sh AND Wx IN ZEA MA YS WITH REFERENCE TO A CYTOLOGICALLY KNOWN POINT IN THE CHROMOSOME BY BARBARA MCCLINTOCE (2001) (0)
- Cyto-Genetics in 1932 (1932) (0)
- Letter from Barbara McClintock to George W. Beadle (1972) (0)
- Talk on genomes (1983) (0)
- "Memorandum to Marcus Rhoades (about the Ds Locus)" [Appendix] (1949) (0)
- "The Ds Locus. Part III. Transposition of the Ds Locus" (Title Page and Table of Contents) (1949) (0)
- Letter from Barbara McClintock to Melvin Green (1968) (0)
- Letter from Barbara McClintock to F. G. Brieger (1962) (0)
- Introduction to Study of Variegation in Maize (1954) (0)
- Gene Control Mechanisms in Higher Organisms: Two Common Types and Several Special Types (1964) (0)
- Letter from Barbara McClintock to Marcus M. Rhoades (1950) (0)
- Letter from Barbara McClintock to Frank Press, National Academy of Sciences (1991) (0)
- Continuation of Inheritance Behavior in Ac (1954) (0)
- "Mode of Operation of a System of Controlling Elements in Maize" (pages 1-31) (1956) (0)
- Principles Derived from Study of Bacterial and Phage Genetic Systems (1964) (0)
- List of McClintock publications (1984) (0)
- Letter from Barbara McClintock to Harold Frank Robinson (1962) (0)
- The Mechanism of Transposition of Ds; Origin and Behavior of cm-1 (1954) (0)
- Draft of letter from Barbara McClintock to Angel Kato (1970) (0)
- Letter from Barbara McClintock to William L. Brown (1959) (0)
- Alteration of Gene Action by Genetic Mechanisms (1958) (0)
- The Inheritance Behavior and the Mode of Action of Ac (1954) (0)
- "Mode of Operation of a System of Controlling Elements in Maize" (Appendix) (1956) (0)
- The Interpretation of Origin and Behavior of the Controlling Systems (1954) (0)
- Changes in State of Ac -- the Effects; Breakage-fusion-bridge Cycles in Endosperm; Transposition of Ds (Begin) (1954) (0)
- [Barbara McClintock's Curriculum Vitae] (1967) (0)
- A METHOD FOR MAKING ACETO-CARMIN SMEARS (1997) (0)
- Letter from Barbara McClintock to W. Ronnie Coffman (1990) (0)
- Review of Previous Discussions (1954) (0)
- Degree of spread of mutation along the chromosome induced by Ds (1956) (0)
- Further study of the a1m-1 Spm system (1956) (0)
- Letter from Barbara McClintock to David H. Timothy (1959) (0)
- Gene-Control Mechanisms in Higher Organisms. Part II (1964) (0)
- Expanding Concepts in Genetics (1971) (0)
- Polypoidy in Zea mays L. (0)
- Six Plants Examined in Each Race (1963) (0)
- :.HE PRODUCTION OF HOMOZYGOUS DEFICIENT TISSUES ,’ WITH MUTAST CHARACTERISTICS BY ME-AX’S OF i \ THE ABERRANT MITOTIC BEHAVIOR OF RING-SHAPED CHROMOSOIMES* (2001) (0)
- Letter from Barbara McClintock to Charles R. Burnham (1931) (0)
- The Origin and Behavior of c-m2; The Origin and Behavior of wx-m1 (1954) (0)
- Letter from Barbara McClintock to Oliver E. Nelson, Jr. (1970) (0)
- Conclusions on c-m1; Outline of bz-m1; Begin c-m2 (1954) (0)
- Nobel Prize Banquet (1983) (0)
- MUTABLE LOCI IN MAIZE t, (2001) (0)
- [Unpublished index of corn specimens] (section 4, image 4) (1971) (0)
- Letter from Barbara McClintock to Elizabeth H. Blackburn (1983) (0)
- Continuation of Discussion of wx-m1; The Induction of Mutability at Selected Loci; The States of a1-m3 (1954) (0)
- Continuation of Transposition of Ac; and its Relation to Somatic Sectoring and to Controls of Mutation of Mutable Genes (1954) (0)
- Continuation of Transposition of Ds; Locations of Ds in Short Arm of Chromosome 9. The Missing Regions; Why. The States of Ds (1954) (0)
- Letter from Barbara McClintock to Almiro Blumenschein (1966) (0)
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