Concetta DiRusso
Biochemistry researcher
Concetta DiRusso's AcademicInfluence.com Rankings
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Biology
Concetta DiRusso's Degrees
- Bachelors Biochemistry University of California, Berkeley
- PhD Biochemistry Stanford University
Why Is Concetta DiRusso Influential?
(Suggest an Edit or Addition)According to Wikipedia, Concetta DiRusso is an American scientist and Professor of Biochemistry. She is best known for her work on transcriptional regulation of fatty acid metabolism in bacteria. Biography DiRusso received her B.A. from Hampshire College, and in 1982 she completed her Ph.D. in cell and molecular biology from the University of Vermont. In 2015, she was invested with the George Holmes University Professorship in Biochemistry at the University of Nebraska-Lincoln DiRusso is a Fellow of the American Association for the Advancement of Science. In 2014, she served as Jefferson Science Fellow in the Global Health Bureau of the United States Agency for International Development.
Concetta DiRusso's Published Works
Published Works
- Fatty acid transporter 2 reprograms neutrophils in cancer (2019) (261)
- Multiple Factors Independently RegulatehilA and Invasion Gene Expression in Salmonella enterica Serovar Typhimurium (2000) (237)
- Transmembrane Movement of Exogenous Long-Chain Fatty Acids: Proteins, Enzymes, and Vectorial Esterification (2003) (228)
- Characterization of FadR, a global transcriptional regulator of fatty acid metabolism in Escherichia coli. Interaction with the fadB promoter is prevented by long chain fatty acyl coenzyme A. (1992) (187)
- A method for extracting high-molecular-weight deoxyribonucleic acid from fungi. (1982) (180)
- Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation. (2007) (178)
- Cloning, sequencing, and expression of the fadD gene of Escherichia coli encoding acyl coenzyme A synthetase. (1992) (177)
- Disruption of the Saccharomyces cerevisiae Homologue to the Murine Fatty Acid Transport Protein Impairs Uptake and Growth on Long-chain Fatty Acids* (1997) (157)
- The Acyl-CoA Synthetases Encoded within FAA1 andFAA4 in Saccharomyces cerevisiaeFunction as Components of the Fatty Acid Transport System Linking Import, Activation, and Intracellular Utilization* (2001) (155)
- Mutational Analysis of a Fatty Acyl-Coenzyme A Synthetase Signature Motif Identifies Seven Amino Acid Residues That Modulate Fatty Acid Substrate Specificity* (1997) (153)
- Molecular and biochemical analyses of fatty acid transport, metabolism, and gene regulation in Escherichia coli. (1994) (152)
- Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family Published, JLR Papers in Press, August 1, 2004. DOI 10.1194/jlr.E400002-JLR200 (2004) (152)
- The structural basis of acyl coenzyme A‐dependent regulation of the transcription factor FadR (2001) (148)
- Comparative Biochemical Studies of the Murine Fatty Acid Transport Proteins (FATP) Expressed in Yeast* (2005) (141)
- Integrated quantitative analysis of nitrogen stress response in Chlamydomonas reinhardtii using metabolite and protein profiling. (2014) (133)
- Molecular inroads into the regulation and metabolism of fatty acids, lessons from bacteria. (1999) (131)
- Functional Role of Fatty Acyl-Coenzyme A Synthetase in the Transmembrane Movement and Activation of Exogenous Long-chain Fatty Acids (2002) (128)
- Long-chain Acyl-CoA Synthetase 6 Preferentially Promotes DHA Metabolism* (2005) (121)
- Role of the Escherichia coli FadR regulator in stasis survival and growth phase-dependent expression of the uspA, fad, and fab genes (1996) (117)
- Crystal structure of FadR, a fatty acid‐responsive transcription factor with a novel acyl coenzyme A‐binding fold (2000) (110)
- The fats of Escherichia coli during infancy and old age: regulation by global regulators, alarmones and lipid intermediates (1998) (109)
- Fatty Acid Transport in Saccharomyces cerevisiae (2002) (104)
- Bacterial Long Chain Fatty Acid Transport: Gateway to a Fatty Acid-responsive Signaling System* (2004) (99)
- Vectorial Acylation in Saccharomyces cerevisiae (2003) (91)
- Two different pathways are involved in the β‐oxidation of n‐alkanoic and n‐phenylalkanoic acids in Pseudomonas putida U: genetic studies and biotechnological applications (2001) (86)
- Analysis of Acyl Coenzyme A Binding to the Transcription Factor FadR and Identification of Amino Acid Residues in the Carboxyl Terminus Required for Ligand Binding (*) (1995) (85)
- Long-chain acyl-CoA-dependent regulation of gene expression in bacteria, yeast and mammals. (2000) (83)
- Primary sequence of the Escherichia coli fadBA operon, encoding the fatty acid-oxidizing multienzyme complex, indicates a high degree of homology to eucaryotic enzymes (1990) (75)
- The medium-/long-chain fatty acyl-CoA dehydrogenase (fadF) gene of Salmonella typhimurium is a phase 1 starvation-stress response (SSR) locus. (1999) (69)
- Hepatic Gene Expression Changes in Mouse Models with Liver-specific Deletion or Global Suppression of the NADPH-Cytochrome P450 Reductase Gene (2005) (63)
- Long-chain fatty acid transport in bacteria and yeast. Paradigms for defining the mechanism underlying this protein-mediated process. (1999) (58)
- Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking. (2008) (58)
- Characterization of the Fatty Acid-responsive Transcription Factor FadR (1997) (56)
- Fatty Acyl-CoA Binding Domain of the Transcription Factor FadR (1998) (54)
- Human Fatty Acid Transport Protein 2a/Very Long Chain Acyl-CoA Synthetase 1 (FATP2a/Acsvl1) Has a Preference in Mediating the Channeling of Exogenous n-3 Fatty Acids into Phosphatidylinositol* (2011) (54)
- Long-chain fatty acid transport in Escherichia coli. Cloning, mapping, and expression of the fadL gene. (1985) (50)
- Triacylglycerol synthesis during nitrogen stress involves the prokaryotic lipid synthesis pathway and acyl chain remodeling in the microalgae Coccomyxa subellipsoidea (2015) (49)
- Fatty acid transport by vectorial acylation in mammals: roles played by different isoforms of rat long-chain acyl-CoA synthetases. (2006) (49)
- Murine FATP alleviates growth and biochemical deficiencies of yeast fat1Delta strains. (2000) (48)
- A live-cell high-throughput screening assay for identification of fatty acid uptake inhibitors. (2005) (46)
- Fatty Acid Transport Proteins: Targeting FATP2 as a Gatekeeper Involved in the Transport of Exogenous Fatty Acids. (2016) (45)
- Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking. (2007) (43)
- Cloning and characterization of a gene (fadR) involved in regulation of fatty acid metabolism in Escherichia coli (1985) (43)
- Functional domains of the fatty acid transport proteins: studies using protein chimeras. (2008) (41)
- Fatty acyl CoA esters as regulators of cell metabolism. (1995) (40)
- Dietary omega-3 and omega-6 polyunsaturated fatty acids modulate hepatic pathology. (2018) (38)
- Nucleotide sequence of the fadR gene, a multifunctional regulator of fatty acid metabolism in Escherichia coli. (1988) (37)
- Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death. (2015) (37)
- Dietary polyunsaturated fatty acids (C18:2 omega6 and C18:3 omega3) do not suppress hepatic lipogenesis. (2008) (37)
- Rapid Detection and Quantification of Triacylglycerol by HPLC–ELSD in Chlamydomonas reinhardtii and Chlorella Strains (2013) (35)
- Targeting the fatty acid transport proteins (FATP) to understand the mechanisms linking fatty acid transport to metabolism. (2009) (35)
- Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae1[OPEN] (2017) (35)
- Vectorial Acylation in Saccharomyces cerevisiae Fat1p AND FATTY ACYL-CoA SYNTHETASE ARE INTERACTING COMPONENTS OF A FATTY ACID IMPORT COMPLEX* (2003) (34)
- Affinity Labeling Fatty Acyl-CoA Synthetase with 9-p-Azidophenoxy Nonanoic Acid and the Identification of the Fatty Acid-binding Site* (2000) (33)
- Combining Mass Spectrometry and NMR Improves Metabolite Detection and Annotation. (2018) (32)
- Overexpression of human fatty acid transport protein 2/very long chain acyl-CoA synthetase 1 (FATP2/Acsvl1) reveals distinct patterns of trafficking of exogenous fatty acids. (2013) (32)
- Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival (2018) (29)
- Fatty Acid Transport in Saccharomyces cerevisiae DIRECTED MUTAGENESIS OF FAT1 DISTINGUISHES THE BIOCHEMICAL ACTIVITIES ASSOCIATED WITH Fat1p* (2002) (26)
- Identification and characterization of small compound inhibitors of human FATP2. (2010) (26)
- Topology of the yeast fatty acid transport protein Fat1p: mechanistic implications for functional domains on the cytosolic surface of the plasma membrane Published, JLR Papers in Press, August 6, 2007. (2007) (25)
- Rat Long Chain Acyl-CoA Synthetase 5, but Not 1, 2, 3, or 4, Complements Escherichia coli fadD* (2004) (24)
- Carbon and Acyl Chain Flux during Stress-induced Triglyceride Accumulation by Stable Isotopic Labeling of the Polar Microalga Coccomyxa subellipsoidea C169* (2016) (23)
- High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias Published, JLR Papers in Press, October 10, 2007. (2008) (22)
- Immune regulation and anti-cancer activity by lipid inflammatory mediators. (2018) (21)
- Energetics underlying the process of long-chain fatty acid transport. (1999) (21)
- Mechanistic studies of the long chain acyl-CoA synthetase Faa1p from Saccharomyces cerevisiae. (2007) (21)
- Innovations in improving lipid production: Algal chemical genetics. (2018) (21)
- Direct interaction of Saccharomyces cerevisiae Faa1p with the Omi/HtrA protease orthologue Ynm3p alters lipid homeostasis (2006) (20)
- Defining a relationship between dietary fatty acids and the cytochrome P450 system in a mouse model of fatty liver disease. (2011) (18)
- Phenotypic screening identifies Brefeldin A/Ascotoxin as an inducer of lipid storage in the algae Chlamydomonas reinhardtii (2015) (17)
- Fatty acid transport protein 2 reprograms neutrophils in cancer (2019) (16)
- Methods to monitor Fatty Acid transport proceeding through vectorial acylation. (2009) (16)
- Deletion of fatty acid transport protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes (2020) (15)
- Fatty acid transport protein-2 inhibitor Grassofermata/CB5 protects cells against lipid accumulation and toxicity. (2015) (15)
- Novel DNA-Sepharose purification of the FadR transcription factor. (1994) (15)
- Triglyceride quantification by catalytic saturation and LC–MS/MS reveals an evolutionary divergence in regioisometry among green microalgae (2014) (14)
- Long-Chain Omega-3 Polyunsaturated Fatty Acids Modulate Mammary Gland Composition and Inflammation (2018) (12)
- Induction of oil accumulation by heat stress is metabolically distinct from N stress in the green microalgae Coccomyxa subellipsoidea C169 (2018) (12)
- Corrigendum to “Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation” [Biochim. Biophys. Acta 1771 (2007) 286–298] (2007) (11)
- The amino-terminal region of the long-chain fatty acid transport protein FadL contains an externally exposed domain required for bacteriophage T2 binding. (2000) (11)
- FadR, fatty acid responsive transcription factor from E. coli (2000) (10)
- Reactive Oxygen Species (ROS) mediated degradation of organophosphate pesticides by the green microalgae Coccomyxa subellipsoidea (2020) (10)
- Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation (2019) (8)
- Orotidylate decarboxylase activity in Schizophyllum commune (1983) (7)
- The Role of Long Chain Acyl-CoA Esters in the Regulation of Gene Expression and Metabolism in Escherichia Coli (1996) (7)
- Crystallization and X-ray diffraction studies of the fatty-acid responsive transcription factor FadR from Escherichia coli. (2000) (6)
- Remodeling of Chlamydomonas Metabolism Using Synthetic Inducers Results in Lipid Storage during Growth1[OPEN] (2019) (6)
- Possible roles of long-chain fatty Acyl-CoA esters in the fusion of biomembranes. (2000) (5)
- Multiple forms of brain adenylate cyclase: stimulation by Mn2+. (1977) (5)
- Remodeling of Chlamydomonas Metabolism Using Synthetic Inducers Results in Lipid Storage during Growth1 [OPEN]. (2019) (3)
- High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias (2020) (3)
- Deletion of fatty acid transport protein 2 (FATP2) in the mouse liver changes the metabolic landscape by increasing the expression of PPARα-regulated genes. (2020) (3)
- Healthy pregnancies and essential fats: focus group discussions with Zambian women on dietary need and acceptability of a novel RUSF containing fish oil DHA (2020) (2)
- Erratum: Characterization of FadR, a global transcriptional regulator of fatty acid metabolism in Escherichia coli (The Journal of Biological Chemistry (1992) 267 (8685-8691)) (1992) (2)
- Long-chain fatty acid transport in bacteria andyeast. Paradigms for defining the mechanism underlying this protein-mediated process (2004) (2)
- Long-chain omega-3 polyunsaturated fatty acids decrease mammary tumor growth, multiorgan metastasis and enhance survival (2018) (1)
- Editorial [Hot Topic: Dietary Lipid Absorption (Guest Editors: C.C. DiRusso and P.N. Black)] (2009) (1)
- Corrigendum to “Identification and characterization of small compound inhibitors of human FATP2” [Biochem. Pharmacol. 79 (2010) 990–999] (2012) (1)
- Complementation of the mammalian fatty acid transport protein in the yeast s. cerevis1ae containing a deltion in iati (1998) (0)
- Remodeling of Chlamydomonas Metabolism UsingSynthetic Inducers Results in Lipid Storageduring Growth (2019) (0)
- Dietary regulation of hepatic and extra‐hepatic lipid metabolism in the liver specific NADPH‐cytochrome P450 reductase knockout model (2006) (0)
- High throughput screening systems for identification of fatty acid uptake inhibitors (2006) (0)
- Impact of DHA status on serum markers of obesity and inflammation in pregnant women (1001.4) (2014) (0)
- Fatty acid transport protein chimeras define functional domains (2006) (0)
- Evaluation of n‐3 fatty acid status of pregnant women in Zambia with relation to HIV infection (2019) (0)
- Characterization of the Biochemical Activities Associated with Splice Variants of Human FATP2 (2008) (0)
- Quantitative analysis of the green microalga Coccomyxa subellipsoidea C169 reveals homeostasis of complex lipid synthesis retained during nitrogen stress (605.14) (2014) (0)
- Inflammatory and Nutritional Biomarkers in the Plasma of Women in Zambia Reflect Low DHA and HIV Status (2019) (0)
- Effects of Lipid Activating Chemical Compounds on the Growth and Production of Fatty Acids and Metabolites in Green Algae (2018) (0)
- Novel Cyclobutene and Cyclobutane-functionalized Fatty Acids are Incorporated into Complex Lipids and Impact Function of HepG2 Cellsa (2016) (0)
- Distinguishing Biochemical Activities of Splice Variants of Human FATP2 (2010) (0)
- Exploring the effects of FATP2 gene deletion on fatty acid‐responsive gene expression in liver (2019) (0)
- Fatty acid transporter 2 regulates the suppressive functions of PMN-MDSC in cancer (2019) (0)
- Discovery of small molecule hyperlipid accumulating triggers of algae Chlamydomonas reinhardtii identified via in vivo phenotype based screen (597.1) (2014) (0)
- Dietary Poly Unsaturated Fatty Acid (PUFA) regulation of Organ and Tissue Microenvironments in an Iso-Caloric Pair-Fed Mouse Model (2016) (0)
- Identification and characterization of inhibitors of hsFATP‐dependent fatty acid uptake in humanized yeast and human Caco‐2 cells (2008) (0)
- IDENTIFICATION OF INHIBITORS OF ACSVL3, A THERAPEUTIC TARGET IN GLIOMA (2017) (0)
- Effect of dietary fatty acids on lipid profile and gene expression in blood, skeletal muscle, adipose, liver and intestine (2010) (0)
- Quantifying Pathways of Stress-Induced TG Synthesis in Algae 1 Carbon and Acyl Chain Flux During Stress-Induced Triglyceride Accumulation by Stable Isotopic Labeling of the Polar Microalga Coccomyxa subellipsoidea C 169 (2016) (0)
- Evaluation of Compounds that Inhibit Fatty Acid Uptake in Mice (2016) (0)
- Dietary fatty acid composition modulates parallel shifts in the metabolic profiles of mice and gut microbiota populations (637.7) (2014) (0)
- Comparative studies of human fatty acid transport proteins 1, 4 and 6 in the vectorial acylation of exogenous long chain fatty acids (2008) (0)
- Identi fi cation and Metabolite Pro fi ling of Chemical Activators of Lipid Accumulation in Green Algae 1[OPEN] (2017) (0)
- Effects of Dietary Fatty Acids on Hepatic Function and Gene Expression in a Model of Hepatic Steatosis (2008) (0)
- Co-cultures of Coccomyxa subellipsoidea and Psuedomonas denitrificans increases lipid accumulation independent of nutrient conditions (2022) (0)
- Abstract 4323: Dietary omega-3 suppress mammary tumor growth, metastasis and enhances survival in an iso-caloric pair-fed mice model (2016) (0)
- Remediation of Nitrate in Drinking Water and Accumulation of Lipids using Microalgae (2020) (0)
- RNA seq Analysis of Livers from Mice Lacking Fatty Acid Transport Protein 2 (FATP2) Demonstrate Metabolic Linkages in Genes Involved in PPARa‐responsive Lipid Metabolic Pathways (2019) (0)
- FADR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI IN COMPLEX WITH FADB OPERATOR (2001) (0)
- Lipid Homeostasis, Chemistry of (2008) (0)
- Abstract 245: Dietary long-chain omega-3 fatty acids reduce adipose inflammation in mammary tissue of mice fed moderate fat-isocaloric diets (2017) (0)
- Mechanistic Enzyme Studies of Acyl‐CoA Synthetase (2006) (0)
- Proteolysis of a fatty acid transport protein defines a region which is hypothesized to represent a fatty acid-specific channel (1998) (0)
- Small molecule inhibitors of fatty acid uptake in 3T3‐L1, primary human adipocytes, INS‐1E and C2C12 cell lines (2010) (0)
- Identification of Two Splice Variants of Human FATP2, Which Distinguish Fatty Acid Transport and Activation Activities (2007) (0)
- Reactive Oxygen Species (ROS) mediated degradation of organophosphate T pesticides by the green microalgae (2020) (0)
- Editorial: Dietary Lipid Absorption (2009) (0)
- Computational Modeling of Human Fatty Acid Transport Protein 2 (2017) (0)
- The med i um-/long-cha in fatty acy l-CoA dehydrogenase (fadF) gene of Salmonella typhimurium is a phase I starvation-stress (1999) (0)
- FadR, FATTY ACID RESPONSIVE TRANSCRIPTION FACTOR FROM E. COLI, in complex with myristoyl-CoA (2001) (0)
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