Daniel Nathans
#3,426
Most Influential Person
American Microbiologist
Why Is Daniel Nathans Influential?
(Suggest an Edit or Addition)According to Wikipedia, Daniel Nathans was an American microbiologist. He shared the 1978 Nobel Prize in Physiology or Medicine for the discovery of restriction enzymes and their application in restriction mapping. Early life and education Nathans was born in Wilmington, Delaware, the last of nine children born to Russian Jewish immigrant parents, Sarah and Samuel Nathans. During the Great Depression his father lost his small business and was unemployed for a long time.
Daniel Nathans's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc. (1987) (754)
- DNA binding activities of three murine Jun proteins: Stimulation by Fos (1988) (725)
- A gene activated in mouse 3T3 cells by serum growth factors encodes a protein with "zinc finger" sequences. (1988) (645)
- A gene activated by growth factors is related to the oncogene v-jun. (1988) (631)
- Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun. (1992) (524)
- DNA binding site of the growth factor-inducible protein Zif268. (1989) (519)
- Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells. (1985) (482)
- A gene inducible by serum growth factors encodes a member of the steroid and thyroid hormone receptor superfamily. (1988) (478)
- jun-D: a third member of the jun gene family. (1989) (411)
- Restriction endonucleases in the analysis and restructuring of dna molecules. (1975) (400)
- A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity (1991) (395)
- Induction of protooncogene c-jun by serum growth factors. (1988) (381)
- Letter: A suggested nomenclature for bacterial host modification and restriction systems and their enzymes. (1973) (376)
- Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3. (1995) (362)
- PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS. (1964) (353)
- An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene. (1991) (344)
- Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae. (1971) (333)
- Growth factor-induced delayed early response genes (1992) (313)
- rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein. (1994) (298)
- Studies of simian virus 40 DNA. VII. A cleavage map of the SV40 genome. (1973) (298)
- Isolation of mutants of an animal virus in bacteria. (1980) (270)
- A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence. (1990) (250)
- Amino acid transfer from aminoacyl-ribonucleic acids to protein on ribosomes of Escherichia coli. (1961) (206)
- In vitro activation of Stat3 by epidermal growth factor receptor kinase. (1996) (205)
- Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene (1983) (205)
- Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors. (1988) (201)
- Local mutagenesis: a method for generating viral mutants with base substitutions in preselected regions of the viral genome. (1978) (197)
- Bidirectional replication of Simian Virus 40 DNA. (1972) (180)
- Structural Requirements for Puromycin Inhibition of Protein Synthesis (1963) (179)
- Functional serum response elements upstream of the growth factor-inducible gene zif268 (1989) (175)
- Multivalent DNA-binding properties of the HMG-1 proteins. (1996) (157)
- Inhibition of aminoacyl-sRNA binding to ribosomes by tetracycline (1965) (154)
- Isolation of cloned cDNA encoding mammalian ornithine decarboxylase. (1984) (153)
- Functional differences between Stat3alpha and Stat3beta (1997) (150)
- Growth-related changes in specific mRNAs of cultured mouse cells. (1983) (150)
- Specific Ablation of Stat3β Distorts the Pattern of Stat3-Responsive Gene Expression and Impairs Recovery from Endotoxic Shock (2002) (149)
- Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family. (1984) (146)
- Deletion mutants of simian virus 40 generated by enzymatic excision of DNA segments from the viral genome. (1974) (144)
- Trophoblastic giant cells of the mouse placenta as the site of proliferin synthesis. (1988) (141)
- Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants (1983) (141)
- Mutational analysis of the simian virus 40 replicon: pseudorevertants of mutants with a defective replication origin. (1979) (139)
- Identification of proliferin mRNA and protein in mouse placenta. (1985) (135)
- Translational regulation of mammalian ornithine decarboxylase by polyamines. (1985) (133)
- Nucleotide sequence of murine ornithine decarboxylase mRNA. (1985) (126)
- The isolation of simian virus 40 variants with specifically altered genomes. (1974) (124)
- Identification of simian virus 40 protein A (1977) (122)
- Mapping temperature-sensitive mutants of simian virus 40: rescue of mutants by fragments of viral DNA. (1974) (121)
- A map of temperature-sensitive mutants of simian virus 40. (1975) (119)
- Regulatory mutants of simian virus 40. Effect of mutations at a T antigen binding site on DNA replication and expression of viral genes. (1982) (116)
- A new member of the prolactin‐growth hormone gene family expressed in mouse placenta. (1985) (115)
- Biosynthesis of the coat protein of coliphage f2 by E. coli extracts. (1962) (114)
- The basic region of Fos mediates specific DNA binding. (1989) (110)
- Genes induced by serum growth factors (1991) (105)
- Metal binding properties and secondary structure of the zinc-binding domain of Nup475. (1996) (105)
- A map of simian virus 40 transcription sites expressed in productively infected cells. (1973) (103)
- Regulatory mutants of simian virus 40: constructed mutants with base substitutions at the origin of DNA replication. (1979) (97)
- Cold-sensitive regulatory mutants of simian virus 40. (1980) (97)
- The evolution of new species of viral DNA during serial passage of simian virus 40 at high multiplicity. (1973) (91)
- Posttranscriptional Selection of Simian Virus 40-Specific RNA (1975) (87)
- Specific origin in SV40 DNA replication. (1972) (85)
- The genome of simian virus 40. (1977) (78)
- Intestinal transport of amino acids studies in vitro with L-[1311] monoiodotyrosine. (1960) (74)
- An endothelial cell growth factor from the mouse neuroblastoma cell line NB41. (1989) (74)
- Genomic response to growth factors. (1988) (69)
- THE FORMATION OF MYELOMA PROTEIN BY A MOUSE PLASMA CELL TUMOR (1958) (69)
- INHIBITION OF PROTEIN SYNTHESIS BY PUROMYCIN. (1964) (68)
- Purification of simian virus 40 large T antigen by immunoaffinity chromatography (1985) (63)
- Cell-free protein synthesis directed by coliphage MS2 RNA: synthesis of intact viral coat protein and other products. (1965) (63)
- Synergistic Activity of STAT3 and c-Jun at a Specific Array of DNA Elements in the α2-Macroglobulin Promoter* (2001) (62)
- Evolutionary variants of simian virus 40: cloned substituted variants containing multiple initiation sites for DNA replication. (1975) (59)
- Transcriptional regulatory elements downstream of the JunB gene. (1993) (59)
- Evolutionary variants of simian virus 40: characterization of cloned complementing variants. (1975) (59)
- Regulation of protein synthesis directed by coliphage MS2 RNA. II. In vitro repression by phage coat protein. (1969) (58)
- Regulation of protein synthesis directed by coliphage MS2 RNA. I. Phage protein and RNA synthesis in cells infected with suppressible mutants. (1969) (56)
- Mammalian Sug1 and c-Fos in the nuclear 26S proteasome. (1996) (55)
- Directed mutagenesis. (1981) (55)
- Evolutionary variants of simian virus 40: Cellular DNA sequences and sequences at recombinant joints of substituted variants. (1978) (49)
- Non-specific termination of simian virus 40 DNA replication. (1975) (49)
- Translation of the genome of a ribonucleic acid bacteriophage. (1972) (47)
- A colinear map relating the simian virus 40 (SV40) DNA segments of six adenovirus-SV40 hybrids to the DNA fragments produced by restriction endonuclease cleavage of SV40 DNA. (1974) (46)
- Evolutionary variants of simian virus 40: Nucleotide sequence of a conserved SV40 DNA segment containing the origin of viral DNA replication as an inverted repetition. (1978) (46)
- Local mutagenesis within deletion loops of DNA heteroduplexes. (1982) (46)
- Restriction endonucleases, simian virus 40, and the new genetics. (1979) (46)
- BACTERIOPHAGE-SPECIFIC PROTEINS IN E. COLI INFECTED WITH AN RNA BACTERIOPHAGE* (1966) (45)
- Characterization of a rearrangement in viral DNA: mapping of the circular simian virus 40-like DNA containing a triplication of a specific one-third of the viral genome. (1974) (44)
- Simian virus 40 mutant T antigens with relaxed specificity for the nucleotide sequence at the viral DNA origin of replication (1984) (44)
- The nucleic acid of an SV40-like virus isolated from a patient with progressive multifocal leukoencephalopathy. (1973) (44)
- Fate of maturation protein during infection by coliphage MS2. (1971) (43)
- Biological activities of deletion mutants of simian virus 40. (1976) (43)
- Studies of SV40 DNA. 3. Differences in DNA from various strains of SV40. (1972) (42)
- Suppression of a VP1 mutant of simian virus 40 by missense mutations in serine codons of the viral agnogene (1983) (42)
- Mouse adenovirus: growth of plaque-purified FL virus in cell lines and characterization of viral DNA. (1977) (41)
- Mapping the genes of simian virus 40. (1975) (38)
- Differential synthesis of bacteriophage-specific proteins in MS2-infected Escherichia coli treated with actinomycin. (1966) (37)
- Deletion mutants of SV40 that affect the structure of viral tumor antigens. (1980) (35)
- The B/C gene of simian virus 40. (1976) (34)
- A transcriptional map of the SV40 genome in transformed cell lines. (1975) (33)
- Amino acid transfer from sRNA to microsome. 2. Isolation of a heat-labile factor from liver supernatant. (1960) (33)
- trans-dominant defective mutants of simian virus 40 T antigen (1987) (32)
- Differential inhibition of coliphage MS2 protein synthesis by ribosome-directed antibiotics. (1972) (31)
- Studies of SV 40 DNA. V. Conversion of circular to linear SV 40 DNA by restriction endonuclease from Escherichia coli B. (1973) (30)
- Cell-free protein synthesis directed by colphage MS2 RNA: sequential synthesis of specific phage proteins. (1967) (30)
- Evolutionary variants of simian virus 40: replication and encapsidation of variant DNA. (1979) (29)
- Protein synthesis from aminoacyl-soluble ribonucleic acid. (1962) (28)
- Studies of SV40 DNA. VI. Cleavage of SV40 DNA by restriction endonuclease from Hemophilus parainfluenzae. (1973) (28)
- Alignment of the restriction map of mouse adenovirus FL with that of human adenovirus 2. (1979) (28)
- COLIPHAGE MS2 CONTAINING 5-FLUOROURACIL. I. PREPARATION AND PHYSICAL PROPERTIES. (1965) (27)
- Effect of L-arginine on elevated blood ammonia levels in man. (1957) (27)
- Secretion of proliferin. (1987) (24)
- Characterization of cloned evolutionary variants of simian virus 40. (1975) (24)
- Functional Differences between Stat3a and Stat3b (1997) (23)
- Sites of origin and removal of blood ammonia formed during glycine infusion: effect of L-arginine. (1958) (23)
- Association of bacteriophage proteins and RNA in E. coli infected with MS2. (1967) (22)
- The mouse aquaporin-1 gene. (1995) (21)
- Characterization of "heavy" and "light" SV40-like particles from a patient with PML. (1974) (18)
- Letter: Potential biohazards of recombinant DNA molecules. (1974) (16)
- Coliphage MS2 containing 5-fluorouracil. II. RNA-deficient particles formed in the presence of 5-fluorouracil. (1967) (14)
- Cooperative transcriptional activity of Jun and Stat3f3, a short form of Stat3 (2005) (12)
- Fragments of MS2 RNA as messengers for specific bacteriophage proteins: fragments from fluorouracil-containing particles. (1968) (10)
- Constructed Mutants of Simian Virus 40 (1979) (9)
- The preparation of coliphage MS 2 containing 5-fluorouracil. (1964) (8)
- [160] Natural RNA coding of bacterial protein synthesis (1968) (8)
- Science Over Politics (1999) (8)
- Acylation of a-Chymotrypsin by Oxygen and Sulfur Esters of Specific Substrates : Kinetic Evidence for a Tetrahedral Intermediate " by (6)
- Mutants of simian virus 40 with base substitutions at the origin of DNA replication. (1979) (6)
- Dissecting the genome of a small tumor virus. (1974) (6)
- In vitro activation of Stat 3 by epidermal growth factor receptor kinase ( signal transduction / growth factors / cytokines / JAK proteins (5)
- Functional Differences between Stat 3 a and Stat 3 b (1997) (5)
- "Potential Biohazards of Recombinant DNA Molecules" [Letter to the Editor of Science] (1974) (4)
- PURIFICATION OF A SUPERNATANT FACTOR THAT STIMULATES AMINO ACID TRANSFER FROM SOLUBLE RIBONUCLEIC ACID TO PROTEIN (1960) (3)
- Use of restriction endonucleases in analyzing the genome of simian virus 40. (1974) (3)
- Translation of the genome of a ribonucleic acid bacteriophage (1972) (2)
- A molecular approach to carcinogenesis: dissecting the genome of a small tumor virus. (1976) (2)
- Transcription Factors Induced by Growth-Stimulating Agents (1991) (2)
- The Gordon Wilson Lecture. The new genetics. (1980) (1)
- Plea to the scientific community. (1982) (1)
- Myeloma proteins and macroglobulins associated with plasma cell tumors in experimental animals. (1960) (1)
- The Johns Hopkins Institutions (1995) (1)
- Viruses in aging and cancer: introductory remarks. (1982) (1)
- Local mutagenesis : A method for generating viral mutants substitutions in preselected regions of the viral genome * (1)
- Letter from Daniel Nathans to Larry Gold (1973) (0)
- Letter from Daniel Nathans to Bernard Weisblum (1973) (0)
- Site-specific mutagenesis in the analysis of a viral replicon. (1980) (0)
- Letter from Daniel Nathans to Ray Wu (1973) (0)
- National Academy of Sciences. Science, An American Bicentennial View. (Washington, D.C.: National Academy of Sciences, 1977 (1978) (0)
- Letter from Daniel Nathans to Maxine Singer (1972) (0)
- Letter from Daniel Nathans to David C. Ward (1971) (0)
- Iron Clearance and Utilization in Rats Using a Direct Method of Counting Fe59 (1954) (0)
- Letter from Daniel Nathans to Wallace P. Rowe (1975) (0)
- Studies of Simian Virus 40 DNA VII. A Cleavage Map of the SV40 Genome (1989) (0)
- Letter from Daniel Nathans to I. Arita (1979) (0)
- Genomic Response to Growth Factors: Progress Report: September, 1991 to July, 1996 (1996) (0)
- Corrections and Clarifications (1995) (0)
- Bacterial Viruses: RNA Phages . Norton D. Zinder, Ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., 1975. x, 428 pp., illus. $28. Cold Spring Harbor Monograph Series. (1975) (0)
- Letter from Daniel Nathans to Ernest Winocour (1969) (0)
- Plea to the Scientific Community (1982) (0)
- Letter from Daniel Nathans to Aaron J. Shatkin (1975) (0)
- Letter from Daniel Nathans to Antonio M. Persico (1992) (0)
- Letter from Daniel Nathans to David McConnell (1973) (0)
- Letter from Daniel Nathans to Senator Tom Harkin (1990) (0)
- Letter from Daniel Nathans to Janet E. Mertz (1974) (0)
- National Academy of Sciences. Research with Recombinant DNA. (Washington, D.C.: National Academy of Sciences, 1977 (1978) (0)
- Letter from Daniel Nathans to Purnell Choppin (1994) (0)
- Tenth miles international symposium: Impact of recombinant molecules on science and society (2004) (0)
- Letter from Daniel Nathans to Roy D. Schmickel (1969) (0)
- Milgram, Stanley. "Subject Reaction: The Neglected Factor in the Ethics of Experimentation." Hastings Center Report, October 1977: 19-23 (1978) (0)
- Simian Virus 40MutantTAntigens withRelaxed Specificity forthe Nucleotide Sequence attheViral DNA Origin ofReplication (1984) (0)
- Memorandum from Daniel Nathans to W. Barry Wood (1969) (0)
- Letter from Daniel Nathans to William F. Harrington (1980) (0)
- Memorandum from Daniel Nathans to Thomas B. Turner (1981) (0)
- DNA Recombination in Cells Infected with Simian Virus 40 (1978) (0)
- Letter from Daniel Nathans to Ernest Winocour and Maxine Singer (1972) (0)
- Mullins, Carolyn J. A Guide to Writing and Publishing in the Social and Behavioral Sciences. (New York: John Wiley and Sons, 1977 (1978) (0)
- Corrections and Clarifications (1995) (0)
- Letter from Daniel Nathans to Kathleen J. Danna (1972) (0)
- 1964 Gordon Research Conference on Nucleic Acids (2008) (0)
- Genomic Response to Growth Factors: Research Review (Period covered: February 1987 to February 1990) (1990) (0)
- National Academy of Sciences. Biographical Memoirs, VOLUME 79 (0)
- Letter from Daniel Nathans to Joshua Lederberg (1978) (0)
- Suppression ofa VP1MutantofSimian Virus40byMissense Mutations inSerine CodonsoftheViral Agnogene (1983) (0)
- Letter from Daniel Nathans to Byron Lane (1984) (0)
- Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae. 1971. (1999) (0)
- The Johns Hopkins Institutions (1995) (0)
- Letter from Daniel Nathans to Paul Berg (1973) (0)
- Effect of ACTH on Distribution of Ascorbic Acid in Rat Adrenal Gland as Determined by Direct Microchemical Analysis (1954) (0)
- Testimony before the House Subcommittee on Science, Research, and Technology. March 30, 1977. Daniel Nathans, Professor and Director, Department of Microbiology, Johns Hopkins University School of Medicine (1977) (0)
- Agricultural Research Lacks Leaders (1975) (0)
- Morse, Philip M. In at the Beginnings: A Physicist's Life. (Cambridge, Massachusetts : The MIT Press, 1977 (1978) (0)
- Maintaining and Nuturing Excellence in Science and Technology (1994) (0)
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