Diether Lambrechts
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(Suggest an Edit or Addition)According to Wikipedia, Diether Lambrechts is a Belgian geneticist and professor at the KU Leuven and VIB. He is the director of the Vesalius Research Center. Lambrechts is known for his multidisciplinary approach to dissecting tumor biology. Major scientific contributions include identifying oxygen supply regulation as an anti-cancer treatment strategy.
Diether Lambrechts's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
- Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. (2010) (1968)
- Large-scale genotyping identifies 41 new loci associated with breast cancer risk (2013) (1063)
- Gene prioritization through genomic data fusion (2006) (924)
- Association analysis identifies 65 new breast cancer risk loci (2017) (922)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death (2003) (881)
- Phenotype molding of stromal cells in the lung tumor microenvironment (2018) (867)
- Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk (2015) (838)
- Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1 (2003) (782)
- Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trial (2011) (736)
- Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes (2018) (559)
- MicroRNA Related Polymorphisms and Breast Cancer Risk (2014) (557)
- Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. (2012) (544)
- Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. (2011) (536)
- Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer (2013) (534)
- Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS (2005) (516)
- Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche (2014) (511)
- VEGF: once regarded as a specific angiogenic factor, now implicated in neuroprotection (2004) (504)
- Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer (2015) (502)
- Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism (2008) (482)
- Prediction of Breast Cancer Risk Based on Profiling With Common Genetic Variants (2015) (471)
- Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene (2009) (452)
- Tumor hypoxia causes DNA hypermethylation by reducing TET activity (2016) (445)
- Gain of function of mutant p53 by coaggregation with multiple tumor suppressors. (2011) (444)
- Underestimated and under-recognized: the late consequences of acute coronary syndrome (GRACE UK-Belgian Study). (2010) (422)
- Thrombomodulin mutations in atypical hemolytic-uremic syndrome. (2009) (420)
- Genome-wide association studies identify four ER negative–specific breast cancer risk loci (2013) (411)
- Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations (2014) (397)
- Role and therapeutic potential of VEGF in the nervous system. (2009) (396)
- Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy. (2016) (379)
- Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival (2008) (367)
- Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk (2017) (359)
- A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor–negative breast cancer in the general population (2010) (357)
- GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer (2013) (350)
- A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24 (2010) (341)
- p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity (2016) (336)
- Neurovascular signalling defects in neurodegeneration (2008) (313)
- Markers of response for the antiangiogenic agent bevacizumab. (2013) (312)
- Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair (2015) (308)
- VEGF: A modifier of the del22q11 (DiGeorge) syndrome? (2003) (307)
- A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor–negative breast cancer (2011) (306)
- PIK3CA Mutations Are Not a Major Determinant of Resistance to the Epidermal Growth Factor Receptor Inhibitor Cetuximab in Metastatic Colorectal Cancer (2009) (304)
- Genome-wide association analysis identifies three new breast cancer susceptibility loci (2012) (291)
- Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis (2018) (288)
- Common variants at 19p13 are associated with susceptibility to ovarian cancer (2010) (262)
- Centrosome Amplification Is Sufficient to Promote Spontaneous Tumorigenesis in Mammals. (2017) (259)
- Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer (2017) (244)
- A genetic Xenopus laevis tadpole model to study lymphangiogenesis (2005) (236)
- Prognostic Significance of POLE Proofreading Mutations in Endometrial Cancer (2014) (229)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer (2020) (225)
- Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancers. (2013) (225)
- Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer. (2014) (221)
- Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening (2019) (211)
- Optimized filtering reduces the error rate in detecting genomic variants by short-read sequencing (2011) (210)
- Genomic Characterization of Primary Invasive Lobular Breast Cancer. (2016) (207)
- A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling (2020) (204)
- The role of fatty acid β-oxidation in lymphangiogenesis (2016) (197)
- Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium. (2011) (192)
- CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (2017) (191)
- Discriminating mild from critical COVID-19 by innate and adaptive immune single-cell profiling of bronchoalveolar lavages (2020) (189)
- Identification of Novel Genetic Markers of Breast Cancer Survival (2015) (185)
- VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials. (2012) (184)
- ABCA transporter gene expression and poor outcome in epithelial ovarian cancer. (2014) (177)
- CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populations (2013) (176)
- The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. (2016) (176)
- Identification of six new susceptibility loci for invasive epithelial ovarian cancer (2014) (176)
- PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS (2016) (174)
- A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer (2021) (169)
- Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer (2013) (167)
- An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates. (2020) (165)
- Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization (2021) (164)
- CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer. (2012) (164)
- Evidence of Gene–Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors (2013) (159)
- Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting (2013) (156)
- A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer (2018) (149)
- Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis (2016) (148)
- Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma (2015) (148)
- Sequencing an Ashkenazi reference panel supports population-targeted personal genomics and illuminates Jewish and European origins (2014) (146)
- Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. (2016) (146)
- Genome-wide association study identifies a common variant associated with risk of endometrial cancer (2011) (142)
- Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis. (2018) (138)
- Germline Mutation in BRCA1 or BRCA2 and Ten-Year Survival for Women Diagnosed with Epithelial Ovarian Cancer (2014) (135)
- Somatic Mutation Profiling and Associations With Prognosis and Trastuzumab Benefit in Early Breast Cancer (2013) (133)
- Transient PLK4 overexpression accelerates tumorigenesis in p53-deficient epidermis (2015) (132)
- The P450 oxidoreductase *28 SNP is associated with low initial tacrolimus exposure and increased dose requirements in CYP3A5-expressing renal recipients. (2011) (132)
- Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties. (2013) (130)
- Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations (2017) (127)
- Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity (2020) (125)
- Common breast cancer susceptibility loci are associated with triple-negative breast cancer. (2011) (124)
- Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 (2016) (122)
- Identification of nine new susceptibility loci for endometrial cancer (2018) (122)
- Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk (2013) (120)
- Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration (2008) (117)
- 19p13.1 is a triple-negative-specific breast cancer susceptibility locus. (2012) (115)
- Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes (2016) (113)
- Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (2014) (112)
- HIF-1α Promotes Glutamine-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics to Support Postimplantation Bone Cell Survival. (2016) (111)
- Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 (2013) (110)
- Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2019) (110)
- Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. (2013) (109)
- Expression profiling of budding cells in colorectal cancer reveals an EMT-like phenotype and molecular subtype switching (2016) (109)
- Lessons from the adjuvant bevacizumab trial on colon cancer: what next? (2011) (107)
- Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization. (2015) (107)
- The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema. (2010) (106)
- Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium (2015) (104)
- VEGF at the neurovascular interface: therapeutic implications for motor neuron disease. (2006) (103)
- Somatic Profiling of the Epidermal Growth Factor Receptor Pathway in Tumors from Patients with Advanced Colorectal Cancer Treated with Chemotherapy ± Cetuximab (2013) (101)
- Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2 (2021) (101)
- Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study (2010) (100)
- Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study. (2016) (96)
- Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer (2016) (95)
- The role of genetic breast cancer susceptibility variants as prognostic factors. (2012) (95)
- Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib (2013) (94)
- Role of Gas6 in erythropoiesis and anemia in mice. (2008) (92)
- Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency. (2012) (90)
- Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium. (2011) (90)
- Lipid availability determines skeletal progenitor cell fate via SOX9 (2020) (88)
- Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association Consortium. (2018) (86)
- Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1. (2015) (86)
- No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing (2016) (83)
- The Association of the 4q25 Susceptibility Variant for Atrial Fibrillation With Stroke Is Limited to Stroke of Cardioembolic Etiology (2010) (83)
- Meta-analysis of vascular endothelial growth factor variations in amyotrophic lateral sclerosis: increased susceptibility in male carriers of the −2578AA genotype (2008) (82)
- Genome-wide significant risk associations for mucinous ovarian carcinoma (2015) (81)
- Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (2019) (81)
- Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis. (2018) (80)
- Matrix-Binding Vascular Endothelial Growth Factor (VEGF) Isoforms Guide Granule Cell Migration in the Cerebellum via VEGF Receptor Flk1 (2010) (79)
- Lineage-specific functions of TET1 in the postimplantation mouse embryo (2017) (79)
- Association Between BRCA 1 and BRCA 2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer (2012) (77)
- BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. (2016) (76)
- High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma. (2013) (75)
- Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2019) (74)
- Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks (2014) (73)
- Uncovering the genomic heterogeneity of multifocal breast cancer (2015) (73)
- Chromosomal Instability in Cell-Free DNA as a Highly Specific Biomarker for Detection of Ovarian Cancer in Women with Adnexal Masses (2016) (72)
- Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models (2020) (70)
- Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer (2017) (70)
- Shared genetics underlying epidemiological association between endometriosis and ovarian cancer. (2015) (68)
- Low expression VEGF haplotype increases the risk for tetralogy of Fallot: a family based association study (2005) (68)
- Genetic modifiers of CHEK2*1100delC associated breast cancer risk (2016) (68)
- The Cancer Cell Oxygen Sensor PHD2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts. (2015) (68)
- Shared heritability and functional enrichment across six solid cancers (2018) (67)
- BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer. (2017) (67)
- Microglial Upregulation of Progranulin as a Marker of Motor Neuron Degeneration (2010) (67)
- Implementing liquid biopsies into clinical decision making for cancer immunotherapy (2017) (66)
- Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response (2018) (65)
- Five endometrial cancer risk loci identified through genome-wide association analysis (2016) (64)
- A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome: the GRACE Genetics Study. (2010) (64)
- Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation (2016) (63)
- Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association Consortium (2014) (62)
- Genetic variability in the multidrug resistance associated protein-1 (ABCC1/MRP1) predicts hematological toxicity in breast cancer patients receiving (neo-)adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide (FEC). (2013) (62)
- Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts (2017) (61)
- Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients (2011) (61)
- Adult body mass index and risk of ovarian cancer by subtype: a Mendelian randomization study. (2016) (60)
- Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a chemicogenetic study in Xenopus tadpoles. (2008) (60)
- Integrated genome analysis of uterine leiomyosarcoma to identify novel driver genes and targetable pathways (2018) (60)
- Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) (2012) (60)
- Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesis (2008) (58)
- Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex. (2017) (58)
- Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus (2016) (58)
- The molecular genetic basis of ovarian cancer and its roadmap towards a better treatment. (2010) (58)
- The Role of KRAS rs61764370 in Invasive Epithelial Ovarian Cancer: Implications for Clinical Testing (2011) (56)
- Genetic variants in CDC42 and NXPH1 as susceptibility factors for constipation and diarrhoea predominant irritable bowel syndrome (2013) (56)
- Vascular endothelial growth factor counteracts the loss of phospho‐Akt preceding motor neurone degeneration in amyotrophic lateral sclerosis (2007) (56)
- Genetic overlap between endometriosis and endometrial cancer: evidence from cross‐disease genetic correlation and GWAS meta‐analyses (2018) (56)
- Lipid availability determines fate of skeletal progenitor cells via SOX9 (2020) (55)
- Biology of breast cancer during pregnancy using genomic profiling. (2014) (55)
- Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer (2016) (54)
- Clinical and genetic risk factors for epirubicin-induced cardiac toxicity in early breast cancer patients (2015) (54)
- Mixed adenoneuroendocrine carcinoma of the colon: molecular pathogenesis and treatment. (2014) (53)
- Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer (2019) (53)
- Functional Polymorphisms in the TERT Promoter Are Associated with Risk of Serous Epithelial Ovarian and Breast Cancers (2011) (53)
- Systemic anti-vascular endothelial growth factor therapies induce a painful sensory neuropathy. (2012) (52)
- Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. (2015) (51)
- Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma. (2021) (51)
- CYP19A1 fine-mapping and Mendelian randomization: estradiol is causal for endometrial cancer (2015) (50)
- Opportunities and Challenges in the Genetics of COPD 2010: An International COPD Genetics Conference Report (2011) (50)
- Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2 (2015) (50)
- Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer (2015) (50)
- Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy (2018) (49)
- Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition (2018) (49)
- Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast (2014) (49)
- Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies (2013) (49)
- Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer. (2016) (49)
- Clinical practice guidelines for BRCA1 and BRCA2 genetic testing. (2021) (48)
- Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies. (2015) (48)
- Genetic evidence for a role of IL33 in nasal polyposis (2010) (47)
- VEGF: necessary to prevent motoneuron degeneration, sufficient to treat ALS? (2004) (47)
- Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk (2014) (47)
- The diagnostic value of next generation sequencing in familial nonsyndromic congenital heart defects (2015) (47)
- Genetic predisposition to ductal carcinoma in situ of the breast (2016) (46)
- DNA methylation in imprinted genes IGF2 and GNASXL is associated with prenatal maternal stress (2015) (45)
- VEGFR1 single nucleotide polymorphisms associated with outcome in patients with metastatic renal cell carcinoma treated with sunitinib – a multicentric retrospective analysis (2014) (45)
- Tamoxifen Metabolism and Efficacy in Breast Cancer: A Prospective Multicenter Trial (2018) (44)
- Genome-wide association study of germline variants and breast cancer-specific mortality (2019) (44)
- The role of KRAS, BRAF, NRAS, and PIK3CA mutations as markers of resistance to cetuximab in chemorefractory metastatic colorectal cancer. (2009) (44)
- Influence of 23 coronary artery disease variants on recurrent myocardial infarction or cardiac death: the GRACE Genetics Study. (2013) (44)
- Genomic signatures as predictive biomarkers of homologous recombination deficiency in ovarian cancer. (2017) (44)
- Neuronal FLT1 receptor and its selective ligand VEGF‐B protect against retrograde degeneration of sensory neurons (2011) (44)
- Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy (2014) (44)
- Prediction of lymph node involvement in breast cancer from primary tumor tissue using gene expression profiling and miRNAs (2011) (43)
- Genomic copy number determines functional expression of {beta}-defensin 2 in airway epithelial cells and associates with chronic obstructive pulmonary disease. (2010) (43)
- Olmsted syndrome: exploration of the immunological phenotype (2013) (43)
- Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study (2017) (42)
- Allele-specific DNA methylation reinforces PEAR1 enhancer activity. (2016) (42)
- Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10. (2014) (42)
- A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling (2020) (41)
- A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium. (2014) (40)
- Exome sequencing reveals HINT1 mutations as a cause of distal hereditary motor neuropathy (2013) (40)
- DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer (2020) (40)
- Genome-Wide Association Study Identifies a Possible Susceptibility Locus for Endometrial Cancer (2012) (39)
- Influence of rs5065 atrial natriuretic peptide gene variant on coronary artery disease. (2012) (39)
- Somatic copy number alterations predict response to platinum therapy in epithelial ovarian cancer. (2014) (39)
- Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. (2015) (39)
- Fine‐scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer (2016) (38)
- 11q13 is a susceptibility locus for hormone receptor positive breast cancer (2012) (38)
- Body mass index and breast cancer survival: a Mendelian randomization analysis (2017) (38)
- Impaired Autonomic Regulation of Resistance Arteries in Mice With Low Vascular Endothelial Growth Factor or Upon Vascular Endothelial Growth Factor Trap Delivery (2010) (37)
- Epigenetic effects of carbon nanotubes in human monocytic cells (2017) (37)
- Self-Maintaining Gut Macrophages Are Essential for Intestinal Homeostasis (2019) (37)
- Assessment of Hepatocyte Growth Factor in Ovarian Cancer Mortality (2011) (37)
- An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates. (2020) (37)
- Comprehensive fine mapping of chr12q12-14 and follow-up replication identify activin receptor 1B (ACVR1B) as a muscle strength gene (2011) (36)
- Chronic Fatigue Syndrome and DNA Hypomethylation of the Glucocorticoid Receptor Gene Promoter 1F Region: Associations With HPA Axis Hypofunction and Childhood Trauma (2015) (36)
- Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ/δ mouse model of amyotrophic lateral sclerosis (2010) (36)
- Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk (2015) (36)
- High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification (2021) (35)
- An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression. (2016) (35)
- Genetics in zebrafish, mice, and humans to dissect congenital heart disease: insights in the role of VEGF. (2004) (35)
- Investigation of gene‐environment interactions between 47 newly identified breast cancer susceptibility loci and environmental risk factors (2015) (35)
- Combined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk (2020) (35)
- Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk (2014) (34)
- Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response (2016) (34)
- Genetic variability in drug transport, metabolism or DNA repair affecting toxicity of chemotherapy in ovarian cancer (2015) (34)
- Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer (2016) (34)
- Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21 (2016) (33)
- Another angiogenic gene linked to amyotrophic lateral sclerosis. (2006) (33)
- Confirmation of 5p12 As a Susceptibility Locus for Progesterone-Receptor–Positive, Lower Grade Breast Cancer (2011) (33)
- Evaluation of efficacy and safety markers in a phase II study of metastatic colorectal cancer treated with aflibercept in the first-line setting (2015) (33)
- Vascular endothelial growth factor pathway in endometriosis: genetic variants and plasma biomarkers. (2016) (33)
- Identification of New Genetic Susceptibility Loci for Breast Cancer Through Consideration of Gene‐Environment Interactions (2014) (33)
- Randomized phase II CLIO study on olaparib monotherapy versus chemotherapy in platinum-resistant ovarian cancer. (2019) (33)
- Whole-genome sequencing reveals a coding non-pathogenic variant tagging a non-coding pathogenic hexanucleotide repeat expansion in C9orf72 as cause of amyotrophic lateral sclerosis (2012) (33)
- Improved metabolite identification with MIDAS and MAGMa through MS/MS spectral dataset-driven parameter optimization (2016) (33)
- Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus (2016) (32)
- Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1 (2015) (32)
- Sculpting Heart Valves with NFATc and VEGF (2004) (32)
- A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast (2020) (32)
- The TERT-CLPTM1L locus for lung cancer predisposes to bronchial obstruction and emphysema (2011) (32)
- Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study (2015) (31)
- DNA methylation analysis of Homeobox genes implicates HOXB7 hypomethylation as risk factor for neural tube defects (2015) (31)
- DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance (2020) (31)
- Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study (2014) (31)
- Common germline polymorphisms associated with breast cancer-specific survival (2015) (31)
- Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium (2015) (31)
- Mutation profile and clinical outcome of mixed endometrioid-serous endometrial carcinomas are different from that of pure endometrioid or serous carcinomas (2015) (31)
- PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (2022) (30)
- Single-cell transcriptome analysis of the Akimba mouse retina reveals cell-type-specific insights into the pathobiology of diabetic retinopathy (2020) (30)
- Pharmaco-epigenomics: discovering therapeutic approaches and biomarkers for cancer therapy (2010) (30)
- Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk. (2018) (29)
- Amplification of 1q32.1 Refines the Molecular Classification of Endometrial Carcinoma (2017) (29)
- IL1β Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D (2020) (29)
- Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models. (2015) (28)
- Phospholipase C gamma 1 (PLCG1) R707Q mutation is counterselected under targeted therapy in a patient with hepatic angiosarcoma (2015) (28)
- Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1 (2017) (28)
- The genetic landscape of 87 ovarian germ cell tumors. (2018) (28)
- Efflux pump ABCB1 single nucleotide polymorphisms and dose reductions in patients with metastatic renal cell carcinoma treated with sunitinib (2014) (28)
- No Association between FTO or HHEX and Endometrial Cancer Risk (2010) (28)
- Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk. (2020) (27)
- Genetic predisposition scores associate with muscular strength, size, and trainability. (2013) (27)
- Epithelial Ovarian Cancer: Rationale for Changing the One-Fits-All Standard Treatment Regimen to Subtype-Specific Treatment (2014) (27)
- Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs) (2016) (27)
- A Complex Network of Tumor Microenvironment in Human High-Grade Serous Ovarian Cancer (2017) (27)
- The Emerging Role of DNA Methylation in Kidney Transplantation: A Perspective (2016) (27)
- A network analysis to identify mediators of germline-driven differences in breast cancer prognosis (2020) (27)
- Genomic and epigenomic analysis of high-risk prostate cancer reveals changes in hydroxymethylation and TET1 (2016) (27)
- Genetic markers of bevacizumab-induced hypertension (2014) (26)
- Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC) (2015) (26)
- Gemcitabine Recruits M2-Type Tumor-Associated Macrophages into the Stroma of Pancreatic Cancer (2020) (26)
- Polymorphisms in Inflammation Pathway Genes and Endometrial Cancer Risk (2012) (26)
- Methylation Defect in Imprinted Genes Detected in Patients with an Albright's Hereditary Osteodystrophy Like Phenotype and Platelet Gs Hypofunction (2012) (26)
- Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk (2015) (25)
- Fat Induces Glucose Metabolism in Nontransformed Liver Cells and Promotes Liver Tumorigenesis (2021) (25)
- A new approach to imprinting mutation detection in GNAS by Sequenom EpiTYPER system. (2010) (25)
- Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer (2020) (25)
- Interleukin-17 receptor polymorphism predisposes to primary graft dysfunction after lung transplantation. (2015) (25)
- Loss of Chromosome 18q11.2-q12.1 Is Predictive for Survival in Patients With Metastatic Colorectal Cancer Treated With Bevacizumab. (2018) (25)
- 9q31.2-rs865686 as a Susceptibility Locus for Estrogen Receptor-Positive Breast Cancer: Evidence from the Breast Cancer Association Consortium (2012) (24)
- A cellular hierarchy in melanoma uncouples growth and metastasis (2022) (24)
- Vitamin D supplementation in cutaneous malignant melanoma outcome (ViDMe): a randomized controlled trial (2017) (24)
- The genomic landscape of nonsmall cell lung carcinoma in never smokers (2019) (24)
- Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis (2009) (24)
- Validation of VEGFR1 rs9582036 as predictive biomarker in metastatic clear‐cell renal cell carcinoma patients treated with sunitinib (2016) (24)
- Molecular characterization of 7 new established cell lines from high grade serous ovarian cancer. (2015) (24)
- Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA (2013) (24)
- Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer. (2015) (23)
- Impact of Selection Bias on Estimation of Subsequent Event Risk (2017) (23)
- VEGF Receptor-2 (Flk-1) Overexpression in Mice Counteracts Focal Epileptic Seizures (2012) (23)
- Comparative oncogenomics identifies tyrosine kinase FES as a tumor suppressor in melanoma (2017) (23)
- Tumor PIK3CA mutations, lymphocyte infiltration, and recurrence-free survival (RFS) in early breast cancer (BC): Results from the FinHER trial. (2012) (23)
- Progesterone receptor gene variants and risk of endometrial cancer. (2011) (23)
- Clinical practices underlie COVID-19 patient respiratory microbiome composition and its interactions with the host (2020) (22)
- Multivariable regression analysis of febrile neutropenia occurrence in early breast cancer patients receiving chemotherapy assessing patient-related, chemotherapy-related and genetic risk factors (2014) (22)
- FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium (2014) (22)
- Ischemia-Induced DNA Hypermethylation during Kidney Transplant Predicts Chronic Allograft Injury. (2018) (22)
- Assessing the genetic architecture of epithelial ovarian cancer histological subtypes (2016) (22)
- Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium (2017) (22)
- Prediction and clinical utility of a contralateral breast cancer risk model (2019) (22)
- Analysis of Over 10,000 Cases Finds No Association between Previously Reported Candidate Polymorphisms and Ovarian Cancer Outcome (2013) (22)
- Impact of genetic variability and treatment-related factors on outcome in early breast cancer patients receiving (neo-) adjuvant chemotherapy with 5-fluorouracil, epirubicin and cyclophosphamide, and docetaxel (2014) (22)
- Regeneration Defects in Yap and Taz Mutant Mouse Livers are Caused by Bile Duct Disruption and Cholestasis. (2020) (22)
- Breast cancer risk variants at 6 q 25 display different phenotype associations and regulate ESR 1 , RMND 1 and CCDC 170 (2016) (22)
- Comprehensive Mutation Analysis in Colorectal Flat Adenomas (2012) (21)
- Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events (2019) (21)
- Epithelial‐Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk (2015) (21)
- Genetic variant in the osteoprotegerin gene is associated with aromatase inhibitor-related musculoskeletal toxicity in breast cancer patients. (2016) (21)
- Gene‐based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms (2017) (20)
- Large-Scale Evaluation of Common Variation in Regulatory T Cell–Related Genes and Ovarian Cancer Outcome (2014) (20)
- Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy (2015) (20)
- Huvariome: a web server resource of whole genome next-generation sequencing allelic frequencies to aid in pathological candidate gene selection (2012) (20)
- The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer (2019) (20)
- Induction and recovery of CpG site specific methylation changes in human bronchial cells after long-term exposure to carbon nanotubes and asbestos. (2020) (20)
- 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy (2014) (19)
- Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy (2015) (19)
- Gene–environment interactions involving functional variants: Results from the Breast Cancer Association Consortium (2017) (19)
- Loss of 1p36.33 Frequent in Low-Grade Serous Ovarian Cancer (2019) (19)
- Association of CDH11 with non‐syndromic ASD (2014) (19)
- Interleukin-6 is an activator of pituitary stem cells upon local damage, a competence quenched in the aging gland (2021) (19)
- Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci (2017) (19)
- Effect of ABCB1 diplotype on tacrolimus disposition in renal recipients depends on CYP3A5 and CYP3A4 genotype (2016) (18)
- GLI2 promoter hypermethylation in saliva of children with a respiratory allergy (2018) (18)
- No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. (2016) (18)
- Heterogeneity in motoneuron disease (2007) (18)
- The BRCA2 c.68‐7T > A variant is not pathogenic: A model for clinical calibration of spliceogenicity (2018) (18)
- Establishment and Characterization of Histologically and Molecularly Stable Soft-tissue Sarcoma Xenograft Models for Biological Studies and Preclinical Drug Testing (2019) (18)
- Cigarette Smoke–Induced Emphysema Exhausts Early Cytotoxic CD8+ T Cell Responses against Nascent Lung Cancer Cells (2018) (17)
- Glucocorticoid receptor DNA methylation and childhood trauma in chronic fatigue syndrome patients. (2018) (17)
- The footprint of the ageing stroma in older patients with breast cancer (2017) (17)
- Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study. (2015) (17)
- Genetic variation in interleukin-17 receptor A is functionally associated with chronic rejection after lung transplantation. (2013) (17)
- Genetic variation in the lymphotoxin-α (LTA)/tumour necrosis factor-α (TNFα) locus as a risk factor for idiopathic achalasia (2013) (16)
- Transcriptome-wide association study of breast cancer risk by estrogen-receptor status (2020) (16)
- Phylogenetic reconstruction of breast cancer reveals two routes of metastatic dissemination associated with distinct clinical outcome (2020) (16)
- Genetic changes in nonepithelial ovarian cancer (2013) (16)
- Genetic modifiers of CHEK 2 * 1100 delC-associated breast cancer risk (2017) (15)
- A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers (2021) (15)
- 1414 POSTER Single Nucleotide Polymorphism Analysis and Outcome in Advanced-stage Cancer Patients Treated With Bevacizumab (2011) (15)
- The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients (2015) (15)
- DNA methylation profiling of non-small cell lung cancer reveals a COPD-driven immune-related signature (2015) (15)
- DNA methylation in imprinted genes IGF2 and GNASXL is associated with prenatal maternal stress (2015) (15)
- Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade. (2014) (14)
- Lung epithelial and myeloid innate immunity in influenza-associated or COVID-19-associated pulmonary aspergillosis: an observational study (2022) (14)
- Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer. (2015) (14)
- Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17 q 21 . 31 (2013) (14)
- Breast Cancer Risk and 6q22.33: Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2 (2012) (14)
- Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium (2021) (14)
- Subsequent Event Risk in Individuals With Established Coronary Heart Disease (2019) (14)
- Prevalent breast cancer patients with a homozygous mutant status for CYP2D6*4: response and biomarkers in tamoxifen users (2009) (14)
- 16LBA VEGFR-1 polymorphisms as potential predictors of clinical outcome in bevacizumab-treated patients with metastatic pancreatic cancer (2009) (13)
- Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer (2020) (13)
- Outcome of Colorectal Cancer Patients Treated with Combination Bevacizumab Therapy: A Pooled Retrospective Analysis of Three European Cohorts from the Angiopredict Initiative (2016) (13)
- Age-related changes in DNA methylation affect renal histology and post-transplant fibrosis. (2019) (13)
- The genetic landscape of 5T models for multiple myeloma (2018) (13)
- Patient-derived cell line models revealed therapeutic targets and molecular mechanisms underlying disease progression of high grade serous ovarian cancer. (2019) (13)
- Establishment and characterization of uterine sarcoma and carcinosarcoma patient-derived xenograft models. (2017) (12)
- Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival. (2020) (12)
- Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study (2018) (12)
- Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (2021) (12)
- TET enzymes as oxygen-dependent tumor suppressors: exciting new avenues for cancer management. (2016) (12)
- Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts (2020) (12)
- Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function (2021) (12)
- Neurodegenerative phenotypes in an A 53 T a-synuclein transgenic mouse model are independent of LRRK 2 (2012) (12)
- Expression of immune‐related genes in rectum and colon descendens of Irritable Bowel Syndrome patients is unrelated to clinical symptoms (2019) (12)
- Detection of microsatellite instability (MSI) in colorectal cancer samples with a novel set of highly sensitive markers by means of the Idylla MSI Test prototype. (2018) (11)
- Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk. (2014) (11)
- Postmortem Examination of an Aggressive Case of Medullary Thyroid Carcinoma Characterized by Catastrophic Genomic Abnormalities. (2017) (11)
- Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (11)
- CRAF mutations in lung cancer can be oncogenic and predict sensitivity to combined type II RAF and MEK inhibition (2019) (11)
- Fine-mapping of the HNF 1 B multicancer locus identi fi es candidate variants thatmediate endometrial cancer risk (2015) (11)
- Polymorphisms in the Von Hippel–Lindau Gene Are Associated With Overall Survival in Metastatic Clear‐Cell Renal‐Cell Carcinoma Patients Treated With VEGFR Tyrosine Kinase Inhibitors (2018) (11)
- Identification and characterization of novel associations in the CASP 8 / ALS 2 CR 12 region on chromosome 2 with breast cancer risk (2014) (11)
- BCL9 regulates CD226 and CD96 checkpoints in CD8+ T cells to improve PD-1 response in cancer (2021) (11)
- Variation in NF-κB Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer (2014) (10)
- Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche DTU Orbit (05/11/2017) (2014) (10)
- Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop. (2022) (10)
- BCL(X)L and BCL2 increase the metabolic fitness of breast cancer cells: a single-cell imaging study (2020) (10)
- Exposure–response analysis of endoxifen serum concentrations in early-breast cancer (2020) (10)
- Randomized CLIO/BGOG-ov10 trial of olaparib monotherapy versus physician's choice chemotherapy in relapsed ovarian cancer. (2022) (10)
- Inherited variants affecting RNA editing may contribute to ovarian cancer susceptibility: results from a large-scale collaboration (2016) (10)
- A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients (2015) (10)
- Establishing a Unified COVID-19 “Immunome”: Integrating Coronavirus Pathogenesis and Host Immunopathology (2020) (10)
- TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer (2017) (10)
- Successful application of endoscopic ultrasound-guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts: a pilot study (2016) (10)
- International Experts Panel Meeting of the Italian Association of Thoracic Oncology on Antiangiogenetic Drugs for Non–Small Cell Lung Cancer: Realities and Hopes (2016) (10)
- Assessment of concordance between fresh-frozen and formalin-fixed paraffin embedded tumor DNA methylation using a targeted sequencing approach (2017) (9)
- PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1 (2017) (9)
- Identification and prioritization of NUAK1 and PPP1CC as positional candidate loci for skeletal muscle strength phenotypes. (2011) (9)
- Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes (2019) (9)
- Polymorphisms in Stromal Genes and Susceptibility to Serous Epithelial Ovarian Cancer: A Report from the Ovarian Cancer Association Consortium (2011) (9)
- Molecular underpinnings of glandular tropism in metastatic clear cell renal cell carcinoma: therapeutic implications (2021) (9)
- Genome-Wide Association Study for Ovarian Cancer Susceptibility Using Pooled DNA (2012) (9)
- Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility (2018) (9)
- Current Methodological Challenges of Single-Cell and Single-Nucleus RNA-Sequencing in Glomerular Diseases (2021) (8)
- Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer (2020) (8)
- Global and gene-specific DNA methylation effects of different asbestos fibres on human bronchial epithelial cells. (2018) (8)
- Corrigendum: The genomic landscape of juvenile myelomonocytic leukemia (2015) (8)
- Variants in the 15q24/25 Locus Associate with Lung Function Decline in Active Smokers (2013) (8)
- Limited potential of genetic predisposition scores to predict muscle mass and strength performance in Flemish Caucasians between 19 and 73 years of age. (2017) (8)
- Molecular Subtypes and Gene Expression Signatures as Prognostic Features in Fully Resected Clear Cell Renal Cell Carcinoma: A Tailored Approach to Adjuvant Trials. (2021) (7)
- Histopathological and Molecular Profiling of Clear Cell Sarcoma and Correlation with Response to Crizotinib: An Exploratory Study Related to EORTC 90101 “CREATE” Trial (2021) (7)
- Immunogenomic, single-cell and spatial dissection of CD8+T cell exhaustion reveals critical determinants of cancer immunotherapy (2021) (7)
- RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue (2018) (7)
- MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma (2021) (7)
- Medicine: Genetic spotlight on a blood defect (2004) (7)
- Multi-tissue transcriptome-wide association study identifies eight candidate genes and tissue-specific gene expression underlying endometrial cancer susceptibility (2021) (7)
- Tumors smother their epigenome (2016) (7)
- Erratum: Gene prioritization through genomic data fusion (2006) (6)
- Microsatellite Instable and Microsatellite Stable Primary Endometrial Carcinoma Cells and Their Subcutaneous and Orthotopic Xenografts Recapitulate the Characteristics of the Corresponding Primary Tumor (2014) (6)
- Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element (2021) (6)
- Common variants in breast cancer risk loci predispose to distinct tumor subtypes (2022) (6)
- Common breast cancer risk loci predispose to distinct tumor subtypes (2019) (6)
- The pulmonary vasculature in lethal COVID-19 and idiopathic pulmonary fibrosis at single-cell resolution (2022) (6)
- Genomic Characterisation and Response to Trastuzumab and Paclitaxel in Advanced or Recurrent HER2-positive Endometrial Carcinoma. (2016) (6)
- Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation (2018) (6)
- Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression (2021) (6)
- Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study. (2011) (6)
- The antitumor effect of metformin with and without carboplatin on primary endometrioid endometrial carcinoma in vivo. (2015) (6)
- LBA78 A microsimulation model to assess the impact of SARS-CoV-2 on cancer outcomes, healthcare organization and economic burden (2020) (6)
- Predictive value of the Leuven HRD test compared with Myriad myChoice PLUS on 468 ovarian cancer samples from the PAOLA-1/ENGOT-ov25 trial (LBA 6) (2022) (6)
- Abstract 986: Unraveling breast cancer progression through geographical and temporal sequencing (2014) (6)
- Comprehensive Molecular Analysis of Inflammatory Myofibroblastic Tumors Reveals Diverse Genomic Landscape and Potential Predictive Markers for Response to Crizotinib (2021) (5)
- CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers (2021) (5)
- Genetic Variation in Caveolin-1 Affects Survival After Lung Transplantation (2014) (5)
- Decoding the activated stem cell phenotype of the neonatally maturing pituitary (2022) (5)
- Whole-genome sequencing reveals a coding non-pathogenic variant tagging a non-coding pathogenic hexanucleotide repeat expansion in C 9 orf 72 as cause of amyotrophic lateral sclerosis (2012) (5)
- FISH analysis of PTEN in endometrial carcinoma. comparison with SNP arrays and MLPA (2014) (5)
- Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women (2019) (5)
- Genetic biomarkers in the VEGF pathway predicting response to anti-VEGF therapy in age-related macular degeneration (2019) (5)
- It's T Time for Normal Blood Vessels. (2017) (5)
- Genetic Variation in Immunoglobulin G Receptor Affects Survival After Lung Transplantation (2014) (4)
- PIK 3 CAMutations Are Not aMajor Determinant of Resistance to the Epidermal Growth Factor Receptor Inhibitor Cetuximab in Metastatic Colorectal Cancer (2009) (4)
- Organoids from human tooth showing epithelial stemness phenotype and differentiation potential (2022) (4)
- Pan-cancer detection and typing by mining patterns in large genome-wide cell-free DNA sequencing datasets (2022) (4)
- Heterogeneity in PHGDH protein expression potentiates cancer cell dissemination and metastasis (2021) (4)
- A genetic predisposition score associates with reduced aerobic capacity in response to acute normobaric hypoxia in lowlanders. (2015) (4)
- Correction: Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC) (2012) (4)
- Combination of variations in inflammation- and endoplasmic reticulum-associated genes as putative biomarker for bevacizumab response in KRAS wild-type colorectal cancer (2020) (4)
- Correction: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer (2016) (4)
- Molecular Biomarkers of Response to Eribulin in Patients with Leiomyosarcoma (2021) (4)
- Publisher Correction: Shared heritability and functional enrichment across six solid cancers (2019) (4)
- Incorporating progesterone receptor expression into the PREDICT breast prognostic model. (2022) (4)
- Pembrolizumab, radiotherapy, and an immunomodulatory five-drug cocktail in pretreated patients with persistent, recurrent, or metastatic cervical or endometrial carcinoma: Results of the phase II PRIMMO study (2022) (4)
- Single-cell Transcriptomics Uncover a Novel Role of Myeloid Cells and T-lymphocytes in the Fibrotic Microenvironment in Peyronie's Disease. (2021) (4)
- Fibroblast Growth Factor Receptor‐2 Polymorphism rs2981582 is Correlated With Progression‐free Survival and Overall Survival in Patients With Metastatic Clear‐cell Renal Cell Carcinoma Treated With Sunitinib (2019) (4)
- POLRMT as a Novel Susceptibility Gene for Cardiotoxicity in Epirubicin Treatment of Breast Cancer Patients (2021) (4)
- Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk (2014) (4)
- Genetic variation at CYP 3 A is associated with age at menarche and breast cancer risk : a case-control study (2014) (4)
- A neural crest stem cell-like state drives nongenetic resistance to targeted therapy in melanoma (2020) (4)
- rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology (2018) (4)
- MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma (2021) (4)
- 700O Kidney ccRCC immune classification (KIC) enhances the predictive value of T effector (Teff) and angiogenesis (Angio) signatures in response to nivolumab (N) (2020) (4)
- A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation (2022) (4)
- A variant at chromosome 9 p 21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome (2010) (4)
- Prospective study evaluating the effect of impaired tamoxifen metabolisation on efficacy in breast cancer patients receiving tamoxifen in the neo-adjuvant or metastatic setting. (2016) (4)
- Single-cell transcriptomics identifies pathogenic T-helper 17.1 cells and pro-inflammatory monocytes in immune checkpoint inhibitor-related pneumonitis (2022) (4)
- Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH 2 B 3 and TSHZ 1 (2015) (4)
- Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer (2016) (3)
- Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis (2022) (3)
- Resistance to Immune Checkpoint Blockade in Uterine Leiomyosarcoma: What Can We Learn from Other Cancer Types? (2021) (3)
- VEGF, a modifier of motor neuron degeneration in SOD1 G93A mice, protects against motor neuron loss after spinal cord ischemia: evidence for a vascular hypothesis (2003) (3)
- O19-3Genome dynamics of the human embryonic kidney 293 (HEK293) lineage in response to cell biology manipulations (2014) (3)
- Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer (2021) (3)
- Severe COVID-19 patients display hyper-activated NK cells and NK cell-platelet aggregates (2022) (3)
- c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of the phase 3 ICON7 trial (2022) (3)
- Emerging single cell endothelial heterogeneity supports sprouting tumour angiogenesis and growth (2021) (3)
- Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci. (2017) (3)
- Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies (2020) (3)
- Breast cancer diagnosed in the post-weaning period is indicative for a poor outcome. (2021) (3)
- PD-003Analysis of single-nucleotide polymorphisms (SNPs) in the phase 3 CORRECT trial of regorafenib vs placebo in patients with metastatic colorectal cancer (mCRC) (2016) (3)
- Mendelian randomisation study of smoking exposure in relation to breast cancer risk (2021) (3)
- A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma (2022) (3)
- Deletion of the hypoxia-response element in the VEGF promoter causes adult onset motor neuron degeneration (2002) (3)
- Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers (2022) (3)
- Association of germline genetic variants with breast cancer-specific survival in patient subgroups defined by clinic-pathological variables related to tumor biology and type of systemic treatment (2021) (3)
- ABCG2 Polymorphism rs2231142 and hypothyroidism in metastatic renal cell carcinoma patients treated with sunitinib (2019) (3)
- Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (2019) (3)
- Mechanical ventilation affects respiratory microbiome of COVID-19 patients and its interactions with the host (2020) (3)
- The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells (2020) (3)
- Abstract P3-07-46: CYPTAM-BRUT 3: Endometrial thickness cannot be used as a marker for tamoxifen metabolization in postmenopausal breast cancer patients (2016) (3)
- Associations between Genetically Predicted Circulating Protein Concentrations and Endometrial Cancer Risk (2021) (3)
- DNA Methylation Repels Binding of HIF Transcription Factors to Maintain Tumour Immunotolerance (2020) (3)
- No Evidence That Genetic Variation in the Myeloid-Derived Suppressor Cell Pathway Influences Ovarian Cancer Survival (2016) (3)
- Molecular characterization of early-stage her2-overexpressing breast cancer (her2+ bc) treated with adjuvant trastuzumab: identification of prognostic groups (2012) (2)
- P5-05-01: Vitamin D Status in Newly Diagnosed Breast Cancer Patients Inversely Correlates with Tumor Size and Moderately Correlates with Outcome. (2011) (2)
- In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis (2022) (2)
- Low 25-hydroxyvitamin d3 serum levels are associated with larger breast tumor size (2011) (2)
- articleDownregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFδ / δ mouse model of amyotrophic lateral sclerosis (2010) (2)
- A pharmacogenomic scoring system predicting median time to progression (mTTP) on sunitinib (SUN) as first-line treatment in patients (pts) with metastatic renal cell carcinoma (mRCC). (2012) (2)
- Identification of a Locus Near ULK1 Associated With Progression-Free Survival in Ovarian Cancer (2021) (2)
- Vitamin D Binding Protein Phenotypes Have An Impact On Vitamin D Substitution In COPD (2011) (2)
- GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide (2022) (2)
- ABCB-1 and VEGFR-3 Single Nucleotide Polymorphisms (SNPs) and Outcome on Sunitinib (SUN) Treatment in Metastatic Clear Cell Renal Cell Carcinoma (RCC) (2011) (2)
- Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (2021) (2)
- Expression profiling of tumour budding cells in colorectal cancer suggests an EMT-like phenotype and molecular subtype switching (2016) (2)
- Melanoma susceptibility variant rs869330 in the MTAP gene is associated with melanoma outcome. (2019) (2)
- Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility (2016) (2)
- Randomized phase II CLIO study on olaparib monotherapy versus chemotherapy in platinum-sensitive recurrent ovarian cancer (2020) (2)
- Two truncating variants in FANCC and breast cancer risk (2019) (2)
- Identification, clinical-pathological characteristics and treatment outcomes of patients with metastatic breast cancer and somatic human epidermal growth factor receptor 2 (ERBB2) mutations (2018) (2)
- Donor Polymorphisms in Common Autoimmunity Genes Are Associated with Acute Renal Allograft Rejection (2011) (2)
- Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci (2017) (2)
- Fine-mapping identi fi es two additional breast cancer susceptibility loci at 9 q 31 . 2 (2015) (2)
- Role for Granulocyte Colony‐Stimulating Factor in Neutrophilic Extramedullary Myelopoiesis in a Murine Model of Systemic Juvenile Idiopathic Arthritis (2022) (2)
- CA-125 Levels Are Predictive of Survival in Low-Grade Serous Ovarian Cancer—A Multicenter Analysis (2022) (2)
- Polymorphisms in In fl ammation Pathway Genes and Endometrial Cancer Risk (2013) (2)
- A pharmacogenomic scoring system predicting median time to progression (mTTP) on sunitinib (SUN) as first-line treatment in patients (pts) with metastatic renal cell carcinoma (mRCC). (2012) (2)
- Inflammasome- and gasdermin D-independent IL-1β production mobilizes neutrophils to inhibit antitumor immunity (2020) (2)
- Accelerated lung function decline in smokers: spotlight on vitamin D deficiency. (2012) (2)
- Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study (2017) (2)
- DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer (2020) (2)
- Erratum: Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations (2017) (2)
- Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study (2022) (2)
- 7115 POSTER DISCUSSION ABCB-1 and VEGFR-3 Single Nucleotide Polymorphisms (SNPs) and Outcome on Sunitinib (SUN) Treatment in Metastatic Clear Cell Renal Cell Carcinoma (RCC) (2011) (2)
- Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer (2022) (2)
- Chromosomal instability in cell-free DNA as a highly specific biomarker for ovarian cancer detection (2016) (2)
- Decoding the activated stem cell phenotype of the vividly maturing neonatal pituitary (2022) (1)
- Functional validation of a genetic locus in the VEGFR-1 tyrosine kinase (TK) domain as a predictive marker for bevacizumab (2012) (1)
- Tuesday, 28 August 2012 (2012) (1)
- Polymorphisms in immunosuppression transporters affect outcome after lung transplantation (2017) (1)
- Genome-wide association study of germline variants and breast cancer-speci fi c mortality (2019) (1)
- Adult height is associated with increased risk of ovarian cancer: a Mendelian randomisation study (2018) (1)
- Abstract P3-07-04: Molecular characterization of mucinous breast cancers (2019) (1)
- Identification of a novel predictive genomic biomarker for response to combination bevacizumab in metastatic colorectal cancer (mCRC). (2017) (1)
- Anticancer immunotherapies transition postcapillary venules into high-endothelial venules that generate TCF1+ T lymphocyte niches through a feed-forward loop (2021) (1)
- Transcriptome Sequencing of Tumor vs. Surrounding Non-Malignant Lung Tissue in Non-Small Cell Lung Cancer (2015) (1)
- Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Breast Cancer Patients. (2022) (1)
- Genetic variation in the STAT3 gene has an impact on survival after lung transplantation (2017) (1)
- A network analysis to identify mediators of germline-driven differences in breast cancer prognosis (2020) (1)
- Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (1)
- Advantages of the Vegf Inhibitor, Macugen: A More Favourable Toxicity Profile (2008) (1)
- A variant in FTO gene shows association with histological ulceration in cutaneous melanoma (2020) (1)
- Association of a novel set of 7 homopolymer indels for detection of MSI with tumor mutation burden and total indel load in endometrial and colorectal cancers. (2018) (1)
- Molecularly targeted therapies for colorectal cancer: Strategies for implementing translational research in clinical trials. (2010) (1)
- Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer. (2015) (1)
- A novel role for VEGF-B in motorneuron degeneration in ALS (2005) (1)
- Syddansk Universitet Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12 p 11 locus (2016) (1)
- Genomic analysis of localized high-risk prostate cancer identifies XPO1 as a potential driver mechanism of metastatic progression (2019) (1)
- Genome-Wide Analysis of Biobanked Blood, Saliva and Cord Blood Identifies DNA Methylation Marks Related to Environmental Programming of Respiratory Allergy (2016) (1)
- Tumour mutational burden ring trial: Evaluation of targeted next-generation sequencing platforms for implementation in clinical practice (2019) (1)
- Prediction and clinical utility of a contralateral breast cancer risk model (2019) (1)
- CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation. (2022) (1)
- Gene-Environment Interactions Relevant to Estrogen and Risk of Breast Cancer: Can Gene-Environment Interactions Be Detected Only among Candidate SNPs from Genome-Wide Association Studies? (2021) (1)
- Pre-treatment cross-talk between the tumoural and peripheral immune system predicts response to checkpoint inhibition in advanced HCC: a single-cell study (2022) (1)
- Erratum to: Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy (2016) (1)
- Abstract S2-05: Characterization and clinical relevance of the genomic alterations defining lobular breast cancer (2015) (1)
- Abstract GS1-06: Unraveling lobular breast cancer progression and endocrine resistance mechanisms through genomic and immune characterization of matched primary and metastatic samples (2019) (1)
- A machine-learning approach for the identification of highly predictive germline SNPs as biomarkers for response to bevacizumab in metastatic colorectal cancer using Elastic Net and Lasso. (2018) (1)
- The Cancer Cell Oxygen S ensor PHD 2 Promotes Metastasis via Activation of Cancer-Associated Fibroblasts Graphical (1)
- Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk (2020) (1)
- Rare germline copy number variants (CNVs) and breast cancer risk (2022) (1)
- Cytotoxic T-lymphocytes and dendritic cells driving the inflammatory micro-environment of Peyronie’s disease (2020) (1)
- Abstract P6-07-14: Mutational and transcriptomic characterization of breast cancer (BC) arising in young patients (pts) and during pregnancy and their associations with long-term outcome (2012) (1)
- Binding Gene . and Correlates with Variants in the Vitamin D Vitamin D Deficiency is Highly Prevalent in COPD (2009) (1)
- Why should results from metastatic trials no longer matter for early-stage disease? (2013) (1)
- Copy number alterations as predictive biomarkers for response to bevacizumab in metastatic colorectal cancer (2016) (1)
- Single-walled and multi-walled carbon nanotubes induce epigenetic alterations in association with the nuclear deposition in 16 HBE cells (2018) (1)
- Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer (2016) (1)
- TP 53-based interaction analysis identifies cis-eQTL variants for TP 53 BP 2 , FBXO 28 , and FAM 53 A that associate with survival and treatment outcome in breast cancer (2017) (1)
- Data describing the poor outcome associated with a breast cancer diagnosis in the post-weaning period (2021) (1)
- Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study (2014) (1)
- High throughput somatic profiling of the Ras-Raf-MAP and PI3K-PTEN-Akt pathways in advanced colorectal cancer and correlations with response to cetuximab (2010) (1)
- Determinants of 25-hydroxyvitamin D Status in a Cutaneous Melanoma Population (2022) (1)
- Abstract 2752: Genetic heterogeneity of ovarian cancer survival effects inBRCA1/2germline mutations: a large, multi-center study (2011) (1)
- Abstract LB-447: Functional validation of a genetic locus in the VEGFR-1 tyrosine kinase (TK) domain as a predictive marker for bevacizumab (2012) (1)
- Correlation of Immunological and Molecular Profiles with Response to Crizotinib in Alveolar Soft Part Sarcoma: An Exploratory Study Related to the EORTC 90101 “CREATE” Trial (2022) (1)
- Identification of nine new susceptibility loci for endometrial cancer (2018) (1)
- Abstract PD3-7: Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analyses in breast cancer (2015) (1)
- Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy (2015) (1)
- Erratum: Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma (2016) (1)
- TP53 mutations in cell-free DNA as early markers of therapeutic response in platinum-resistant relapsed ovarian cancer (PROC): a prospective translational analysis of the phase II GANNET53 clinical trial (2019) (1)
- Abstract CT135: Uncovering the genomic heterogeneity of multifocal breast cancer (2015) (1)
- Fine-mapping of the HNF1Bmulticancer locus identifies candidate variants thatmediate endometrial cancer risk (2015) (1)
- Molecular Heterogeneity Between Paired Primary and Metastatic Lesions from Clear Cell Renal Cell Carcinoma (2022) (1)
- The RNA demethylase FTO controls m6A marking on SARS-CoV-2 and classifies COVID-19 severity in patients (2022) (1)
- Genetic predisposition to ductal carcinoma in situ of the breast (2016) (1)
- DNA hypomethylation of the glucocorticoid receptor gene promoter 1F region in chronic fatigue syndrome (2014) (1)
- PIK3CA mutations do not confer resistance to the EGFR-inhibitor cetuximab in chemorefractory metastatic colorectal cancer (2009) (1)
- CD8+ T-Cell Metabolic Rewiring Defined by Single-Cell RNA-Sequencing Identifies a Critical Role of ASNS Expression Dynamics in T-Cell Differentiation (2021) (1)
- Breast Cancer Risk and 6 q 22 . 33 : Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA 1 / 2 (2012) (1)
- 2022-RA-1136-ESGO A single-cell map of rare ovarian cancer (2022) (1)
- Gene prioritization by genomic data fusion (2007) (1)
- Organoids from mouse molar and incisor as new tools to study tooth-specific biology and development. (2023) (0)
- Abstract P4-06-14: Single-cell RNA sequencing to delineate changes in tumor microenvironment induced by immunotherapy (2019) (0)
- Phenotype molding of stromal cells in the lung tumor microenvironment (2018) (0)
- The impact of baseline and genetic parameters on progression free survival and overall survival in breast cancer patients receiving neoadjuvant or adjuvant chemotherapy with fluorouracil, epirubicin, cyclophosphamide (FEC) and docetaxel (D) (2013) (0)
- Metabolomic and transcriptomic response to imatinib treatment of gastrointestinal stromal tumour in xenograft-bearing mice (2023) (0)
- Genetic variation in FCGR2A is associated with increased mortality after lung transplantation (2013) (0)
- High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification (2021) (0)
- Abstract PD10-10: PD10-10 Single cell characterization of longitudinal biopsies from breast cancer patients treated with the aromatase inhibitors letrozole and exemestane in sequence (2023) (0)
- Differences in MWCNT- and SWCNT-induced DNA methylation alterations in association with the nuclear deposition (2018) (0)
- Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop. (2023) (0)
- DIFFERENTIAL EXPRESSION OF PD-L1, PD1 AND CTLA4 RECEPTOR ACCORDING TO HISTOLOGY AND TUMOUR VS. SURROUNDING NON-MALIGNANT LUNG TISSUE IN NON-SMALL CELL LUNG CANCER: RNA SEQUENCING DATA (2013) (0)
- Complete Genome Sequencing of Monozygotic Twins with Discordant Schizophrenia Phenotypes (2010) (0)
- K-ras mutations and cetuximab in colorectal cancer. (2009) (0)
- Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer (2023) (0)
- TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA (2023) (0)
- PLATELETS AND THROMBOPOIESIS Allele-speci fi c DNA methylation reinforces PEAR1 enhancer activity (2016) (0)
- 1073 Prostate cancer copy number score predicts metastatic disease (2016) (0)
- Imprinting defect in patients with Albright’s Hereditary Osteodystrophy and platelet Gs hypofunction (2012) (0)
- Identification of genetic risk factors associated with idiopathic achalasia by a genetic candidate study (2012) (0)
- Genetic analysis of ovarian cancer progression using full genome sequencing (2010) (0)
- 210 Toll-Like Receptor 4 Polymorphisms and the Risk of Primary Graft Dysfunction after Lung Transplantation (2012) (0)
- Blood flow deficits due to perivascular nerve degeneration: a novel mechanism of ALS (2005) (0)
- PD-L1/PD-L2 gene expression differs in tumor vs. lung tissue in non-small cell lung cancer patients (2016) (0)
- Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry (2023) (0)
- Exploration of the immunological phenotype of Olmsted syndrome (2013) (0)
- European Mathematical Genetics Meeting, Heidelberg, Germany, 12th–13th April 2007 (2007) (0)
- Plasma markers showing differential baseline expression in relapsing versus non-relapsing patients with hormone sensitive breast tumors (2020) (0)
- VEGF protects sensory axons against a retrograde axonopathy: implications for anti-angiogenic therapies (2010) (0)
- MO249SINGLE-CELL TRANSCRIPTOME OF COVID19 ASSOCIATED IGA NEPHROPATHY* (2021) (0)
- 336 Retrospective CYPTAM-BRUT 1 Study Shows Association Between the Genetic Variants Rs1800716 and Rs727479 in Tamoxifen Metabolisation and Tamoxifen-induced Increase in Double Endometrial Thickness (2012) (0)
- CCNE1 and survival of patients with tubo‐ovarian high‐grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study (2022) (0)
- CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers (2021) (0)
- Abstract 2779: A genome-wide analysis of more than 160,000 individuals identifies four novel pleiotropic risk loci shared between breast and ovarian cancer (2015) (0)
- Abstract 4122: TIL-containing patient-derived explant cultures reveal role of metformin on antigen presenting cell activation (2023) (0)
- Abstract OT2-19-01: Single cell characterization of longitudinal biopsies from breast cancer patients treated neoadjuvantly with the aromatase inhibitor letrozole and the CDK4/6 inhibitor ribociclib in concert (2023) (0)
- Abstract 1896: Chromosome 9p21 Polymorphism Interacts With Waist-to-Hip Ratio in Carotid Plaque (2009) (0)
- Multivariable regression analysis of febrile neutropenia occurrence in early breast cancer patients receiving chemotherapy assessing patient-related, chemotherapy-related and genetic risk factors (2014) (0)
- Improved metabolite identification with MIDAS and MAGMa through MS/MS spectral dataset-driven parameter optimization (2016) (0)
- 478. Lung Hybrid Neutrophils and Subsequent Extracellular Traps Are Protective In COVID-19-Associated Pulmonary Aspergillosis (2022) (0)
- Rare copy number variants (CNVs) and breast cancer risk (2021) (0)
- SO009ISCHEMIA IN KIDNEY TRANSPLANTATION CAUSES DNA HYPERMETHYLATION AND PREDICTS GRAFT FIBROSIS: AN EPIGENOME-WIDE ASSOCIATION STUDY (2017) (0)
- Author response: A new protocol for single-cell RNA-seq reveals stochastic gene expression during lag phase in budding yeast (2020) (0)
- Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma (2023) (0)
- Abstract P4-10-07: Genetic predictors of chemotherapy-related amenorrhea (2016) (0)
- GLI2 promoter hypermethylation in saliva of children with a respiratory allergy (2018) (0)
- Discovery of somatic variants in gynaecological cancers using Complete Genomics’ sequencing service (2011) (0)
- VEGF may induce axonal sprouting and preserve neuromuscular junction integrity in vivo (2006) (0)
- The footprint of the ageing stroma in older patients with breast cancer (2017) (0)
- THE EPIGENETIC SIGNATURE OF OLD DONOR KIDNEYS MIGHT BE EXPLAINED BY CHRONIC HYPOXIA (2019) (0)
- Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy (2018) (0)
- Abstract 3402: BCAT1 as a druggable target in immuno-oncology (2020) (0)
- Genome-wide association study of germline variants and breast cancer-specific mortality (2019) (0)
- Association of the CHEK2 c.1100delC variant, radiotherapy, and systemic treatment with contralateral breast cancer risk and breast cancer-specific survival (2023) (0)
- Use of different genetic predisposition score techniques to predict muscle mass and muscle function over the adult life span in Flemish Caucasians (2015) (0)
- The 9p21 locus interacts with obesity to increase atherosclerotic burden (2009) (0)
- Treatment of an aggressive form of motor neuron degeneration by VEGF protein and gene transfer in ALS animal models (2004) (0)
- P115 Quality-of-life analysis in the randomized phase II CLIO trial comparing olaparib with standard chemotherapy in platinum-resistant recurrent ovarian cancer (2019) (0)
- Abstract PO002: Pretreatment immune cell composition and checkpoint ligand expression define the response to immunotherapy in advanced HCC: a study using single-cell sequencing (2022) (0)
- A signature of differential gene expression in bronchoalveolar lavage fluid predicts mortality in influenza-associated pulmonary aspergillosis (2023) (0)
- Genetic and chemico-genetic lymphangiogenesis study of VEGFR-3 and its ligands VEGF-D and VEGF-C in Xenopus laevis tadpoles (2006) (0)
- Olmsted syndrome: immunodysregulation with TRPV3 mutation (2013) (0)
- Abstract 4529: Tailoring approaches for global epigenome analysis from archival formalin-fixed paraffin-embedded tissue samples (2016) (0)
- Validation of the Correlation Between Single Nucleotide Polymorphism rs307826 in VEGFR3 and Outcome in Metastatic Clear-Cell Renal Cell Carcinoma Patients Treated with Sunitinib (2020) (0)
- Author Correction: A cellular hierarchy in melanoma uncouples growth and metastasis (2022) (0)
- Influence of rs5065 Atrial Natriuretic Peptide Gene Variant on Coronary Artery Disease (2012) (0)
- 2022-RA-1473-ESGO Randomized phase II CLIO study on olaparib monotherapy versus chemotherapy in recurrent ovarian cancer – results of the Leuven HRD test (2022) (0)
- Pharmaco‐Epigenomics to Improve Cancer Therapies (2012) (0)
- Sa1597 - Upregulation of Mast Cell Related Genes in Irritable Bowel Syndrome (2018) (0)
- Genome-wide association study of germline variants and breast cancer-speci fi c mortality (2019) (0)
- Human epidermal growth factor receptor 2 mutations and androgen receptor: new therapeutic targets in breast cancer? (2015) (0)
- Somaticcopynumberalterations predictresponsetoplatinumtherapyin epithelial ovarian cancer (2014) (0)
- The impact of patient-related factors on the occurrence of febrile neutropenia in breast cancer patients receiving (neo-)adjuvant chemotherapy with 5-fluorouracil, epirubicin, and cyclofosfamide (FEC) x6 or FEC x3 followed by docetaxel (D) x3. (2013) (0)
- Advanced clear-cell renal cell carcinoma (accRCC): Association of microRNAs (miRNAs) with molecular subtypes, mRNA targets and outcome (2019) (0)
- Abstract PD14-05: Portraying tumor evolution of lobular breast cancer through phylogenetic analysis (2022) (0)
- Abstract P2-08-23: Early intratumoral changes after a single dose of anti-PD-1 treatment in patients with early breast cancer (BC) (2022) (0)
- Abstract 2579: Loss of chromosome 18q11.2-18q12.1 is predictive for progression-free survival in metastatic colorectal cancer patients treated with bevacizumab (2018) (0)
- Abstract B110: The use of patient-derived xenograft models to explore new treatment strategies in uterine sarcomas (2015) (0)
- Edinburgh Research Explorer A variant at chromosome 9p21 is associated with recurrent myocardial infarction and cardiac death after acute coronary syndrome (2017) (0)
- 15 Genetic and molecular validation of uterine sarcoma patient-derived xenograft models (2014) (0)
- Complete genome sequencing of discordant monozygotic twins: finding the differences (2010) (0)
- The MUC5B Promoter Polymorphism is Not Associated With Non-ILD Chronic Respiratory Diseases or Post-transplant Outcome (2022) (0)
- Abstract P5-05-06: ctDNA detection in seven different types of body liquids in patients with metastatic breast cancer (2023) (0)
- Metastases-prone localized prostate cancer: a genomic analysis (2016) (0)
- Abstract P3-05-03: Characterization of PIK3CA mutations in lobular breast cancer (2012) (0)
- Abstract 1118: Absence of mouse-specific tumor evolution in patient-derived cancer xenografts (2020) (0)
- Cell‐type specific insights into the pathobiology of advanced diabetic retinopathy using single‐cell transcriptome analysis of the Akimba retina (2019) (0)
- OP-JNCI200057 329..337 (2021) (0)
- The impact of baseline and genetic parameters on progression free survival and overall survival in breast cancer patients receiving neoadjuvant or adjuvant chemotherapy with fluorouracil, epirubicin and cyclophosphamide (2013) (0)
- Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci (2022) (0)
- A variant at chromosome 9p21 is associated with recurrent myocardial infarction after acute coronary syndrome: The GRACE Genetics Study (2009) (0)
- chemicogenetic study in Xenopus tadpoles Role of VEGF-D and VEGFR-3 in developmental lymphangiogenesis, a (2013) (0)
- Genetic markers of bevacizumab-induced hypertension (2014) (0)
- Mendelian randomization Association of vitamin D levels and risk of ovarian cancer : a Mendelian randomization study (2016) (0)
- New cell line models for the development of personalized therapy for high grade serous ovarian cancer. (2017) (0)
- The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer (2019) (0)
- Genomic analysis of localised prostate cancer identifies AZIN1 as driver of metastatic progression (2019) (0)
- A multi-layered systems approach for renal cell carcinoma (2020) (0)
- Abstract 230: Joint genome-wide association study of endometrial cancer and ovarian cancer identifies a novel genetic risk region at 14q23.3 (2018) (0)
- Characterization of PI3KCA Mutation in Lobular Breast Cancer. (2012) (0)
- HumanVariome: A High Quality Human Variation study and Resource for Rare Variant Detection and Validation (2011) (0)
- Survival after Lung Transplantation Is Linked with a Genetic Polymorphism in Caveolin-1 (2013) (0)
- Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- Abstract PD4-06: PD4-06 Obesity-associated changes in transcriptomic profile and immune landscape of primary breast cancer revealed by bulk and single-cell gene expression data (2023) (0)
- Optimizing The Micro-Environment In A Tissue Engineering Scaffold: A Computational Approach (2010) (0)
- Genetic variability in drug transport, metabolism or DNA repair affecting toxicity of chemotherapy in ovarian cancer (2015) (0)
- Abstract P1-03-05: Genetic variant in the OPG gene is associated with aromatase inhibitor-related musculoskeletal toxicity in breast cancer patients (2015) (0)
- Two-stage fine-mapping of a linkage peak for knee strength on chromosome 12 (2008) (0)
- RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue (2018) (0)
- Genomic instability in high-grade serous ovarian cancer - development of a cell-free DNA based biomarker (2015) (0)
- 208 IL-23R Locus Polymorphism Is Associated with Higher Mortality, after Lung Transplantation (2012) (0)
- OC-0047: PD-L1/PD-L2 gene expression differs in tumor vs. lung tissue in non-small cell lung cancer patients (2016) (0)
- Minimally invasive detection of tumor-specific copy number alterations in the plasma of patients with ovarian cancer (2015) (0)
- Abstract 794: Molecular analysis of archival inflammatory myofibroblastic tumor tissue samples from EORTC 90101 “CREATE” and correlation with response to crizotinib (2020) (0)
- DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance (2020) (0)
- strength in humans Linkage of myostatin pathway genes with knee (2015) (0)
- Abstract 2006: Sequencing of mismatch repair deficient tumors identifies a synthetic lethal interaction with other DNA repair pathways. (2013) (0)
- S3.3d Influenza versus COVID-19-associated pulmonary aspergillosis: Profiling lower respiratory tract epithelial and myeloid innate immunity in patient samples (2022) (0)
- 2022-RA-638-ESGO Pembrolizumab with multimodal immunomodulation in chemotherapy-pretreated cervical, endometrial, and uterine cancer: the PRIMMO phase II trial (2022) (0)
- The impact of genetic variability on severe toxicity of (neo-) adjuvant chemotherapy in breast cancer patients receiving 5-fluorouracil, epirubicin, and cyclofosfamide (FEC). (2012) (0)
- Association of rs12662670 with breast cancer in Asian ER (2012) (0)
- Shared heritability and functional enrichment across six solid cancers (2019) (0)
- Solar Lentigines are Associated with Better Outcome in Cutaneous Melanoma. (2019) (0)
- Abstract P1-01-10: Exome sequencing of circulating tumor cells in metastatic breast cancer (2017) (0)
- The genetic landscape of 5T models for multiple myeloma (2018) (0)
- CHAPTER 19 – VEGF, an Angiogenic Factor with Neurotrophic Activity, Useful for Treatment of ALS? (2006) (0)
- Full genome sequencing of highly rearranged, contaminated tumor samples: a feasibility study (2010) (0)
- MP33-18 CYTOTOXIC T-LYMPHOCYTES AND DENDRITIC CELLS MAINTAINING THE INFLAMMATORY MICRO-ENVIRONMENT OF PEYRONIE'S DISEASE (2020) (0)
- Predictors of pretreatment CA125 at ovarian cancer diagnosis: a pooled analysis in the Ovarian Cancer Association Consortium (2017) (0)
- Data for: Loss of 1p36.33 frequent in low grade serous ovarian cancer (2019) (0)
- KRAS, PIK3CA, TP53 and FBWX7 Mutations as Prognostic Markers For Primary Endometrial Cancer (2011) (0)
- Molecular pathology and functional genomics of lung disease (2011) (0)
- 311 A pharmacogenomic scoring system predicting median time-to-progression on sunitinib as first line treatment in patients with metastatic renal cell carcinoma (2012) (0)
- Abstract P4-03-01: The footprint of the aging stroma in older breast cancer patients (2017) (0)
- SO013AGING IS ASSOCIATED WITH EPIGENETIC CHANGES IN GENES INVOLVED IN FIBROSIS IN THE KIDNEY: AN EPIGENOME-WIDE STUDY (2017) (0)
- Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA (2013) (0)
- RENAL TRANSPLANTATION EXPERIMENTAL AND INFLAMMATION SO009 ISCHEMIA IN KIDNEY TRANSPLANTATION CAUSES DNA HYPERMETHYLATION AND PREDICTS GRAFT FIBROSIS: AN EPIGENOME-WIDE ASSOCIATION STUDY (2017) (0)
- Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis (2021) (0)
- Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- Abstract LB-331: Polymorphisms in inflammation pathway genes and endometrial cancer (2012) (0)
- Quality control of Complete Genomics sequences of germline and fresh tumor derived DNA samples (2010) (0)
- Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology (2022) (0)
- Polygenic risk modeling for prediction of epithelial ovarian cancer risk (2022) (0)
- Rare but Relevant Kidney Disorders (2009) (0)
- A child’s spit epigenome can reveal its respiratory allergy risk (2016) (0)
- Corrigendum to "Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer" [Eur J Cancer 53 (2016) 51-64]. (2016) (0)
- a novel candidate breast cancer susceptibility locus on (2017) (0)
- Abstract A26: The successful application of endoscopic ultrasound guided fine needle biopsy to establish pancreatic patient-derived tumor xenografts (2016) (0)
- Effects of genotoxicity, DNA methylation and transcriptional changes by Carbon Nanotube exposure in vitro (2015) (0)
- Abstract OT2-1-05: Prospective multicenter study evaluating the effect of impaired tamoxifen metabolization on efficacy in breast cancer patients receiving tamoxifen in the neo-adjuvant or metastatic setting - The CYPTAM-BRUT 2 trial (2012) (0)
- Mass-spectrometric analysis of GNAS methylation in Pseudohypoparathyroydism type Ib patients reveals overall methylation defects also for the familial cases (2009) (0)
- randomization Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study (2016) (0)
- Pentraxin-3 Polymorphisms are Associated with Invasive Pulmonary Aspergillosis after Lung Transplantation (2019) (0)
- Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus (2016) (0)
- Chromosome 18q11.2 loss as a predictive marker for response to bevacizumab in metastatic colorectal cancer (2016) (0)
- Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1 (2017) (0)
- Variation in NFk B Signaling Pathways and Survival in Invasive Epithelial Ovarian Cancer (2014) (0)
- 435 Genetic Variability in the Methylenetetrahydrofolate Reductase (NAD(P)H) Gene (MTHFR) is Associated with Severe Non Hematological Toxicity of Adjuvant FEC in Breast Cancer (2012) (0)
- Identification and characterization of four bacteriome- and mycobiome-derived subtypes in tumour and adjacent mucosa tissue of colorectal cancer patients (2022) (0)
- First evidence and experience of patient-derived xenograft models for endometrial cancer (2013) (0)
- The old antibiotic acriflavine inhibits epithelial-to-mesenchymal transition and the unfolded protein response thereby resensitizing resistant hepatoma cells to sorafenib (2016) (0)
- Abstract AS13: Epidemiologic predictors of pre-treatment CA125 in women with ovarian cancer (2015) (0)
- A Genetic Polymorphism in IL-23 Receptor Is Protective for Primary Graft Dysfunction (2014) (0)
- 796 Establishment of Primary Endometrial Carcinoma Cell Cultures as a Preclinical Tool for Drug Screening – Methods and Characterization (2012) (0)
- Gender-specific association of GABBR1 DNA methylation with pregnancy anxiety (2016) (0)
- P1-08-20: Parity Interferes with the Effect of Age at Diagnosis on the Frequency Breast Cancers Are Triple-Negative. (2011) (0)
- The 9p21 locus and arterial stiffening in the general population: results from ASKLEPIOS (2009) (0)
- Title Obesity and survival among women with ovarian cancer : Results from the Ovarian Cancer Association Consortium Permalink (2015) (0)
- P2-06-02: FOXO3a Genotype Predicts Age of Breast Cancer Onset and Correlates with Lymph Node Involvement. (2011) (0)
- Common germline polymorphisms associated with breast cancer-specific survival (2015) (0)
- SNP rs2180341 per-allele hazard ratios (HRs) and 95% confidence intervals (CIs) among Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) in A. BRCA1 mutation carriers B. BRCA2 mutation carriers. (2012) (0)
- Abstract LB-78: Pharmacogenomic analysis of a phase III trial of gemcitabine/axitinib versus gemcitabine/placebo in patients with advanced pancreatic cancer (2010) (0)
- Abstract PR03: Pretreatment immune cell composition and checkpoint ligand expression define the response to immunotherapy in advanced HCC: a study using single-cell sequencing (2022) (0)
- Association of vitamin D deficiency with COPD and vitamin D binding proteins (2009) (0)
- C5aR1 signaling triggers lung immunopathology in COVID-19 through neutrophil extracellular traps. (2023) (0)
- Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations (2019) (0)
- Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer (2022) (0)
- An oncogenomics-based in vivo screen identifies novel melanoma tumor-suppressors (2016) (0)
- Body mass index and breast cancer survival (2017) (0)
- 415 Genetic Variability in Multi Drug Resistance Protein 1 (ABCC1/MRP1) and UDP-Glucuronosyltransferase-2B7 (UGT2B7) Are Highly Correlated with Severe Haematological Toxicity of Adjuvant FEC in Breast Cancer (2012) (0)
- Results in Brief Association between FTO or HHEX and Endometrial B & P cer Risk (2010) (0)
- The successful application of endoscopic ultrasound guided fine needle biopsy to establish pancreatic patient-derived tumor xenogafts (2016) (0)
- Vitamin D Binding Gene . COPD and Correlates with Variants in the Vitamin D Deficiency is Highly Prevalent in (2009) (0)
- Author response: Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks (2014) (0)
- LBA81 Keeping exhausted T-cells in check in COVID-19 (2020) (0)
- MODL-27. PRECLINICAL INTERROGATION OF IMMUNOTHERAPY TREATMENT STRATEGIES IN GLIOBLASTOMA (GBM) USING A CLINICALLY RELEVANT DISEASE MODEL (2022) (0)
- Common variants in breast cancer risk loci predispose to distinct tumor subtypes (2022) (0)
- A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer (2018) (0)
- Development of psoriasiform skin lesions under anti-TNF therapy: a genetic link? (2008) (0)
- DNA hypermethylation caused by ischemia in kidney transplants predicts future chronic injury to the allograft (2017) (0)
- Abstract P6-14-12: Evaluation of changes in sequencing quality and transcriptomic profiles with increasing post-mortem interval: results from an optimization experiment within the UPTIDER tissue donation program (2023) (0)
- GNAS NESP and XL hypermethylation in pseudopseudohypoparathyroidism patients (2011) (0)
- VEGF is a modifier gene of amyotrophic lateral sclerosis in humans (2003) (0)
- Assessing the genetic architecture of epithelial ovarian cancer histological subtypes (2016) (0)
- The assessment of asbestos and carbon nanotubes induced genotoxic effects (2015) (0)
- Whole genome epigenetic and transcriptional effects of exposing human bronchial epithelial cells to single- and multi-wall carbon nanotubes (2016) (0)
- Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis (2022) (0)
- Functional Association between a Genetic Variant in the IL-17 Receptor Gene and Chronic Rejection after Lung Transplantation (2013) (0)
- DOWN-REGULATION OF HYPOXIA INDUCIBLE FACTOR-1_(HIF-1_) EXPRESSION, THROUGH MTOR PATHWAY, BY LETROZOLE IN ER plus VE BREAST CANCER PATIENTS: CLINICAL IMPLICATIONS (2009) (0)
- Abstract P2-03-05: Identification, clinical characteristics and treatment outcomes of somatic human epidermal growth factor receptor 2 (ERBB2) mutations in metastatic breast cancer patients (2017) (0)
- DNA methylation profiling of non-small cell lung cancer reveals an immune signature in COPD patients (2013) (0)
- Analysis of miRNA – microarray data of breast cancer for the prediction of lymph node invasion (2010) (0)
- Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers (2021) (0)
- Abstract 5197: Patient-derived xenograft (PDX) models of soft tissue sarcoma (STS): a preclinical platform for early drug testing (2016) (0)
- FP334THE RENAL EPIGENETIC CLOCK IS A BETTER SURROGATE FOR KIDNEY AGE THAN TELOMERE ATTRITION (2019) (0)
- Hepatoma cells acquiring sorafenib resistance show mesenchymal differentiation driven by DNA methylation and genetic rearrangements (2016) (0)
- Multiomics and spatial mapping characterizes human CD8+ T cell states in cancer (2023) (0)
- Abstract 5785: A pan-cancer single-cell tumor micro-environment atlas predictive of immunotherapy response (2023) (0)
- Genetic markers within the Vascular Endothelial Growth Factor (VEGF) pathway as predictors of the response to the treatment of the Age Related Macular Degeneration (ARMD) (2017) (0)
- Figure 1—source data 2. (2014) (0)
- Activin Receptor 1 B (ACVR1B) as a muscle strength determining gene: genetic fine mapping of chr12q12-14 (2008) (0)
- 0183 Progranulin (PC-derived growth factor) levels in serum do not predict response to neoadjuvant capecitabine (X), docetaxel (T) and trastuzumab (H) for patients (pts) with locally advanced breast cancer (LABC) (2009) (0)
- Abstract PD8-02: Phylogenetic reconstruction of advanced breast cancer reveals two different routes of metastatic dissemination associated with distinct clinical outcome (2020) (0)
- A novel panel to detect microsatellite instability and concordance with clinical reference methods in colorectal cancer patients. (2015) (0)
- Abstract 3397: Post-mortem examination of an aggressive case of medullary thyroid cancer characterised by catastrophic genomic abnormalities (2017) (0)
- The footprint of the aging stroma in older breast cancer patients. (2017) (0)
- Antizyme Inhibitor 1 regulates matrikine expression and enhances the metastatic potential of aggressive primary prostate cancer. (2022) (0)
- Genomic analysis of primary high-risk prostate cancer tumors with metastatic recurrence identifies antizyme inhibitor 1 as a regulator of cancer cell migration through regulation of collagen expression (2018) (0)
- Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes (2020) (0)
- A child's spit epigenome can reveal its respiratory allergy risk (2016) (0)
- BCAT1 inhibition affects CD8+ T cell activation, exhaustion, and tumoral immunity by altering iron homeostasis (2023) (0)
- Abstract 4280: Potential molecular biomarkers of response to eribulin in patients with leiomyosarcoma (2020) (0)
- Association of protective IL13 polymorphism with irritable bowel syndrome (2012) (0)
- Intermediate molecular phenotypes to identify genetic markers of anthracycline-induced cardiotoxicity risk (2023) (0)
- CYPTAM-BRUT 2: A prospective multicenter observational study in the neoadjuvant and metastatic setting investigating tamoxifen response between women with a favorable versus unfavorable endoxifen profile. (2011) (0)
- Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (2022) (0)
- Multi-tissue transcriptome-wide association study identifies genetic mechanisms underlying endometrial cancer susceptibility (2020) (0)
- PS-3-5 Dendritic Cells and Cytotoxic T-Lymphocytes Driving the Inflammation in the Peyronie's Disease Micro-Environment (2020) (0)
- Genetic Biomarkers for Anti-angiogenic Therapies – a Race to Report (2010) (0)
- Exome sequencing of circulating tumor cells in metastatic breast cancer (2016) (0)
- A01*Genomic hallmarks of invasive lobular breast carcinoma and their clinical relevance (2015) (0)
- Edinburgh Research Explorer TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer (2018) (0)
- Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer (2019) (0)
- Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (2019) (0)
- 17AþIFN-cþ Th17/1 cells associated with steroid resistance in nephrotic syndrome through both IL-17A and IFN-c. MO249 SINGLE-CELL TRANSCRIPTOME OF COVID19 ASSOCIATED IGA NEPHROPATHY* (2021) (0)
- PHGDH heterogeneity potentiates cancer cell dissemination and metastasis (2022) (0)
- VEGF inhibitors aggravate ALS, possibly by reducing neural perfusion (2006) (0)
- Abstract 1202: ERG344: A novel IRG1 inhibitor for the treatment of colon cancer (2021) (0)
- University of Birmingham Tumour hypoxia causes DNA hypermethylation by reducing TET activity (2016) (0)
- EP-1149: Influence of histology and smoking status on PD-L1, PD1 and CTLA4 expression of tumor vs. normal lung tissue in NSCLC (2014) (0)
- A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients (2015) (0)
- Timing evolution of lobular breast cancer through phylogenetic analysis (2022) (0)
- Pharmacogenomics in a trial of gemcitabine/axitinib compared with gemcitabine/placebo in advanced pancreatic cancer (2010) (0)
- Genetic variability of VEGF pathway genes in six randomized phase III trials assessing the addition of bevacizumab to standard therapy (2014) (0)
- Genetic variant in the OPG gene is associated with aromatase inhibitor-related musculoskeletal toxicity in breast cancer patients (2015) (0)
- The role of placental growth factor in the nervous system (2008) (0)
- Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression (2021) (0)
- Abstract A75: Serine auxotrophy: A novel metabolic vulnerability of platinum-resistant ovarian cancer? (2020) (0)
- Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses (2020) (0)
- (Epi)genetic variation in ageing of metabolic fitness (2015) (0)
- Abstract 5584: Analysis of cell free DNA to predict outcome to Bevacizumab combination therapy in metastatic colorectal cancer patients (2023) (0)
- 1 Subsequent Event Risk in Individuals with Established Coronary Heart Disease : Design and Rationale of the GENIUS-CHD Consortium Running title : (2019) (0)
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