Julius Axelrod

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Julius Axelrod

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Pharmacology

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Julius Axelrod's Degrees

PhD Pharmacology George Washington University

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Julius Axelrod's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Stress hormones: their interaction and regulation. (1984) (1539)
Enzymatic O-methylation of epinephrine and other catechols. (1958) (1211)
Phospholipid methylation and biological signal transmission. (1980) (1038)
A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE. (1963) (940)
A phospholipase A2 inhibitory protein in rabbit neutrophils induced by glucocorticoids. (1980) (765)
Biochemical and pharmacological changes in the rat following chronic administration of morphine nalorphine and normorphine. (1959) (698)
The pineal gland. (1965) (688)
A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain. (1967) (563)
Ascorbic acid in aromatic hydroxylation. I. A model system for aromatic hydroxylation. (1954) (536)
Control of enzymatic synthesis of adrenaline in the adrenal medulla by adrenal cortical steroids. (1966) (529)
A sensitive and specific fluorescence assay for tissue serotonin. (1965) (522)
Purification and properties of phenylethanolamine-N-methyl transferase. (1962) (520)
Biochemistry of catecholamines. (1971) (510)
Inhibition of Uptake of Tritiated-noradrenaline in the Intact Rat Brain by Imipramine and Structurally Related Compounds (1964) (482)
Receptor-mediated activation of phospholipase A2 via GTP-binding proteins: arachidonic acid and its metabolites as second messengers (1988) (466)
A sensitive enzymatic assay for dopamine- -hydroxylase. (1971) (460)
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. (1993) (455)
Norepinephrine and dopamine content of hypothalamic nuclei of the rat. (1974) (452)
The estimation of antipyrine in biological materials. (1949) (443)
Localizing Tritiated Norepinephrine in Sympathetic Axons by Electron Microscopic Autoradiography (1962) (426)
The fate of H3-norepinephrine in animals. (1961) (414)
Sensitive assay for serotonin N-acetyltransferase activity in rat pineal. (1972) (411)
Effect of drugs on the uptake and metabolism of H3-norepinephrine. (1961) (366)
CONTROL OF HYDROXYINDOLE O-METHYLTRANSFERASE ACTIVITY IN THE RAT PINEAL GLAND BY ENVIRONMENTAL LIGHTING. (1965) (365)
Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline (1958) (356)
Purification and properties of hydroxyindole-O-methyl transferase. (1961) (352)
The fate of melatonin in animals. (1961) (339)
Increase in tyrosine hydroxylase activity after reserpine administration. (1969) (336)
The distribution and properties of a histamine-methylating enzyme. (1959) (333)
Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat (1996) (332)
EFFECT OF DRUGS ON THE UPTAKE, RELEASE, AND METABOLISM OF H3-NOREPINEPHRINE IN THE RAT BRAIN. (1965) (322)
Enzymatic methylation of phosphatidylethanolamine increases erythrocyte membrane fluidity (1978) (322)
Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells. (1986) (321)
The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-amino-phenol, free and total conjugated, in biological fluids and tissues. (1948) (318)
Serum Dopamine‐Beta‐Hydroxylase Activity (1971) (315)
Adrenaline Synthesis: Control by the Pituitary Gland and Adrenal Glucocorticoids (1965) (312)
Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2. (1987) (308)
The physiological disposition of H3-epinephrine and its metabolite metanephrine. (1959) (306)
Regional studies of catecholamines in the rat brain. IV. Effects of drugs on the disposition and metabolism of H3-norepinephrine and H3-dopamine. (1966) (305)
Methylation reactions in the formation and metabolism of catecholamines and other biogenic amines. (1966) (297)
The fate of aminopyrine (pyramidon) in man and methods for the estimation of aminopyrine and its metabolites in biological material. (1950) (285)
beta-Adrenergic receptor agonists increase phospholipid methylation, membrane fluidity, and beta-adrenergic receptor-adenylate cyclase coupling. (1979) (285)
A specific and sensitive enzymatic-isotopic microassay for serotonin in tissues. (1973) (284)
Control of circadian change of serotonin N-acetyltransferase activity in the pineal organ by the beta--adrenergic receptor. (1972) (277)
Trans-synaptic induction of adrenal tyrosine hydroxylase. (1969) (277)
Localisation of phenylethanolamine N-methyl transferase in the rat brain nuclei (1974) (273)
Enzymatic formation of uridine diphosphoglucuronic acid. (1957) (272)
Stimulation of phospholipase A2 activity in bovine rod outer segments by the beta gamma subunits of transducin and its inhibition by the alpha subunit. (1987) (264)
Changes in Central Catecholaminergic Neurons in the Spontaneously (Genetic) Hypertensive Rat (1978) (262)
TYROSINE HYDROXYLASE IN RAT BRAIN: DEVELOPMENTAL CHARACTERISTICS (1972) (259)
The pineal gland. (1970) (258)
The fate of caffeine in man and a method for its estimation in biological material. (1953) (256)
Studies on sympathomimetic amines. II. The biotransformation and physiological disposition of d-amphetamine, d-p-hydroxyamphetamine and d-methamphetamine. (1954) (256)
Fate of Tritiated Noradrenaline at the Sympathetic Nerve-Endings (1961) (255)
METABOLISM OF [3H]NOREPINEPHRINE IN THE RAT BRAIN (1965) (254)
Receptor-mediated activation of phospholipase A2 and arachidonic acid release in signal transduction. (1990) (249)
Chemoattractants stimulate degradation of methylated phospholipids and release of arachidonic acid in rabbit leukocytes. (1979) (249)
Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region. (1974) (248)
The fate of antipyrine in man. (1950) (247)
Rapid changes in rat pineal beta-adrenergic receptor: alterations in l-(3H)alprenolol binding and adenylate cyclase. (1975) (236)
Effect of Cocaine on the Disposition of Noradrenaline labelled with Tritium (1960) (235)
DEVELOPMENT OF THE UPTAKE AND STORAGE OF L‐[3H]NOREPINEPHRINE IN THE RAT BRAIN (1971) (234)
Biosynthesis of melatonin: enzymic conversion of serotonin to N-acetylserotonin. (1960) (230)
Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents (1993) (229)
Adrenaline-forming enzyme in brainstem: elevation in genetic and experimental hypertension. (2003) (225)
Congenital jaundice in rats, due to a defect in glucuronide formation. (1958) (218)
Lack of Uptake of Catecholamines after Chronic Denervation of Sympathetic Nerves (1961) (212)
DOPAMINE‐β‐HYDROXYLASE IN THE RAT BRAIN: DEVELOPMENTAL CHARACTERISTICS (1972) (210)
Stimulation of phospholipid methylation, Ca2+ influx, and histamine release by bridging of IgE receptors on rat mast cells. (1980) (208)
Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes. (1994) (206)
THE FATE OF ACETOPHENETIDIN (PHENACETIN) IN MAN AND METHODS FOR THE ESTIMATION OF ACETOPHENETIDIN AND ITS METABOLITES IN BIOLOGICAL MATERIAL (1949) (205)
Serotonin stimulates phospholipase A2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis. (1990) (204)
A sensitive and specific enzymatic isotopic assay for tissue histamine. (1966) (198)
Neuroprotective Antioxidants from Marijuana a (2000) (195)
Identification and Properties of Methyltransferases That Synthesize Phosphatidylcholine in Rat Brain Synaptosomes (1980) (195)
DISTRIBUTION OF CATECHOL‐O‐METHYL TRANSFERASE IN THE NERVOUS SYSTEM AND OTHER TISSUES (1959) (184)
Identification and properties of two methyltransferases in conversion of phosphatidylethanolamine to phosphatidylcholine. (1978) (183)
The dopamine-1 agonist, SKF 82526, stimulates phospholipase-C activity independent of adenylate cyclase. (1989) (180)
Ascorbic acid in aromatic hydroxylation. II. Products formed by reaction of substrates with ascorbic acid, ferrous ion, and oxygen. (1954) (178)
An enzymatic assay for octopamine and other beta-hydroxylated phenylethylamines. (1969) (178)
The metabolic fate of H3-epinephrine and C14-metanephrine in the rat. (1961) (177)
ENZYMATIC OXIDATION OF URIDINE DIPHOSPHATE GLUCOSE TO URIDINE DIPHOSPHATE GLUCURONIC ACID (1954) (176)
Dopamine- -hydroxylase: regulation of its synthesis and release from nerve terminals. (1972) (175)
Psychotomimetic N-Methylated Tryptamines: Formation in Brain in vivo and in vitro (1972) (175)
The enzymatic N-methylation of serotonin and other amines. (1962) (173)
O-Methylation of catechol amines in vivo. (1958) (173)
PROPERTIES OF NOREPINEPHRINE STORAGE PARTICLES OF THE RAT HEART. (1963) (172)
Phospholipid methylation unmasks cryptic beta-adrenergic receptors in rat reticulocytes. (1979) (172)
The enzymatic deamination of amphetamine (benzedrine). (1955) (172)
The enzymic cleavage of aromatic ethers. (1956) (171)
Enzymatic synthesis and rapid translocation of phosphatidylcholine by two methyltransferases in erythrocyte membranes. (1978) (170)
Effects of drugs on the disposition of H-3-norepinephrine in the rat brain. (1966) (169)
Storage and synthesis of norepinephrine in the reserpine-treated rat brain. (1966) (168)
Coexistence of several putative neurotransmitters in single identified neurons of Aplysia. (1974) (166)
Metabolism of epinephrine and other sympathomimetic amines. (1959) (166)
Increased Tyrosine Hydroxylase Activity after Drug-induced Alteration of Sympathetic Transmission (1969) (166)
Effect of Drugs on the Uptake and Release of 3H-Norepinephrine in the Rat Heart (1962) (162)
THE UPTAKE OF H3-MELATONIN IN ENDOCRINE AND NERVOUS TISSUES AND THE EFFECTS OF CONSTANT LIGHT EXPOSURE. (1964) (161)
The enzymatic N-demethylation of narcotic drugs. (1956) (161)
3-Methoxy-4-hydroxyphenylglycol sulfate, a new metabolite of epinephrine and norepinephrine. (1959) (159)
Intracellular Localization of Catecholamines in Tissues of the Rat (1962) (157)
The fate of acetanilide in man. (1948) (156)
Neurally mediated increase in dopamine-beta-hydroxylase activity. (1970) (156)
Mechanism of the potentiating action of beta-diethylaminoethyl diphenylpropylacetate. (1954) (154)
Hormone secretagogues increase cytosolic calcium by increasing cAMP in corticotropin-secreting cells. (1985) (154)
Induction and superinduction of serotonin N-acetyltransferase by adrenergic drugs and denervation in rat pineal organ. (1972) (150)
Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases. (1981) (149)
Some factors affecting glucuronide formation in vitro. (1960) (149)
Supersensitivity and subsensitivity of the beta-adrenergic receptor in pineal gland regulated by catecholamine transmitter. (1973) (149)
Catecholamine Metabolism in Experimental Hypertension in the Rat (1967) (148)
Rapid Stimulation of protein carboxymethylation in leukocytes by a chemotactic peptide (1978) (148)
Mepacrine blocks beta-adrenergic agonist-induced desensitization in astrocytoma cells. (1980) (147)
Pituitary Gland: Enzymic Formation of Methanol from S-Adenosylmethionine (1965) (147)
Reduced plasma dopamine-beta-hydroxylase activity in familial dysautonomia. (1971) (146)
Stimulation of C14-melatonin synthesis from C14-tryptophan by noradrenaline in rat pineal in organ culture. (1969) (146)
Increase of corticotropin-releasing factor staining in rat paraventricular nucleus neurones by depletion of hypothalamic adrenaline (1984) (145)
THE DISTRIBUTION AND METABOLISM OF LYSERGIC ACID DIETHYLAMIDE (1957) (142)
Inhibitory effects of beta-diethylaminoethyl diphenylpropylacetate on a variety of drug metabolic pathways in vitro. (1954) (142)
Relationship between Sodium Intake and Norepinephrine Storage during the Development of Experimental Hypertension (1968) (142)
Catechol estrogen-forming enzyme of brain: demonstration of a cytochrome p450 monooxygenase. (1977) (140)
CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND. (1965) (139)
Methyltransferase enzymes in red blood cells. (1971) (139)
Circadian cycles in binding of 3H-alprenolol to β-adrenergic receptor sites in rat pineal (1975) (139)
Stimulation of arachidonic acid release and inhibition of mitogenesis by cloned genes for muscarinic receptor subtypes stably expressed in A9 L cells. (1988) (137)
Uptake, storage and metabolism of norepinephrine in tissues of the developing rat. (1967) (137)
THE UPTAKE AND BINDING OF CIRCULATING SEROTONIN AND THE EFFECT OF DRUGS. (1963) (133)
A 24-hour rhythm in the content of norepinephrine in the pineal and salivary glands of the rat. (1966) (132)
A transfected m1 muscarinic acetylcholine receptor stimulates adenylate cyclase via phosphatidylinositol hydrolysis. (1989) (132)
The physiologic disposition and metabolism of norepinephrine in immunosympathectomized animals. (1966) (130)
Association of the changes in cytosolic Ca2+ and iodide efflux induced by thyrotropin and by the stimulation of alpha 1-adrenergic receptors in cultured rat thyroid cells. (1985) (129)
Melatonin Synthesis in the Hen Pineal Gland and its Control by Light (1964) (128)
Effect of steroid hormones, ovariectomy, estrogen pretreatment, sex and immaturity on the distribution of 3H-estradiol. (1966) (128)
THE METABOLISM, STORAGE, AND RELEASE OF CATECHOLAMINES. (1965) (125)
REGIONAL AND SUBCELLULAR DISTRIBUTION OF PROTEIN CARBOXYMETHYLASE IN BRAIN AND OTHER TISSUES (1976) (121)
Transfected D2 dopamine receptors mediate the potentiation of arachidonic acid release in Chinese hamster ovary cells. (1991) (120)
Photic and neural control of the 24-hour norepinephrine rhythm in the rat pineal gland. (1967) (120)
Inhibition of release of dopamine- -hydroxylase and norepinephrine from sympathetic nerves by colchicine, vinblastine, or cytochalasin-B (hypogastric nerve stimulation-exocytosis-microtubules-microfilaments-guinea pig). (1972) (119)
Interrelationships of sodium intake, hypertension, and norepinephrine storage in the rat. (1969) (119)
Turnover and synthesis of norepinephrine in experimental hypertension in rats. (1969) (118)
Central control of the pineal gland: visual pathways. (1968) (118)
Rapid elevation of biogenic amine metabolites in human CSF following probenecid. (1970) (118)
Somatostatin inhibits multireceptor stimulation of cyclic AMP formation and corticotropin secretion in mouse pituitary tumor cells. (1982) (117)
Inhibition of the extraneuronal accumulation and metabolism of norepinephrine by adrenergic blocking agents. (1967) (116)
Actions of bretylium and guanethidine on the uptake and release of [3H]-noradrenaline. (1962) (115)
Benzodiazepine and β-adrenergic receptor ligands independently stimulate phospholipid methylation (1979) (113)
DISTRIBUTION AND TURNOVER OF OCTOPAMINE IN TISSUES (1972) (112)
THE UPTAKE OF CIRCULATING [3H]NOREPINEPHRINE BY THE PITUITARY GLAND AND VARIOUS AREAS OF THE BRAIN (1961) (112)
Enhanced release of dopamine -hydroxylase and norepinephrine from sympathetic nerves by dibutyryl cyclic adenosine 3', 5'-monophosphate and theophylline. (1973) (112)
CHAPTER 5 – The β-Adrenergic Receptor and the Regulation of Circadian Rhythms in the Pineal Gland (1977) (111)
Phospholipid methylation: a biochemical signal modulating lymphocyte mitogenesis. (1980) (111)
The physiological disposition of dicumarol in man. (1950) (111)
THE DISTRIBUTION AND PROPERTIES OF THE NONSPECIFIC N‐METHYLTRANSFERASE IN BRAIN (1973) (110)
EFFECT OF DEXAMETHASONE ON PHENYLETHANOLAMINE N‐METHYLTRANSFERASE IN CHROMAFFIN TISSUE OF THE NEONATAL RAT (1973) (109)
On the mechanism of release of norepinephrine from sympathetic nerves induced by depolarizing agents and sympathomimetic drugs. (1975) (109)
Selectivity of estrogen distribution in tissues. (1965) (109)
Interleukin 1 amplifies receptor-mediated activation of phospholipase A2 in 3T3 fibroblasts. (1988) (108)
PHYSIOLOGICAL DISPOSITION OF H3-NOREPINEPHRINE IN THE DEVELOPING RAT. (1964) (107)
Inhibition of trans-synaptically increased tyrosine hydroxylase activity by cycloheximide and actinomycin D. (1969) (107)
Phospholipid methylation and phospholipase A2 activation in cytotoxicity by human natural killer cells. (1981) (107)
Concanavalin A stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells. (1979) (106)
EFFECTS OF URINARY pH ON AMPHETAMINE METABOLISM (1971) (105)
Influence of Pituitary, Thyroid, and Adrenal Hormones on Norepinephrine Turnover and Metabolismin the Rat Heart (1968) (105)
Increased Ca2+ -ATPase activity associated with methylation of phospholipids in human erythrocytes. (1979) (105)
Mepacrine treatment prevents immobilization-induced desensitization of beta-adrenergic receptors in rat hypothalamus and brain stem (1981) (105)
The uptake and storage of H3-norepinephrine in the reserpine-pretreated rat heart. (1965) (104)
O-methylation, the principal pathway for the metabolism of epinephrine and norepinephrine in the rat. (1958) (102)
Catechol Estrogens: Presence in Brain and Endocrine Tissues (1977) (100)
Histamine content of hypothalamic nuclei of the rat. (1974) (100)
Changes in Enzymes involved in the Biosynthesis and Metabolism of Noradrenaline and Adrenaline after Psychosocial Stimulation (1970) (99)
Inhibition of neuronally induced tyrosine hydroxylase by nicotinic receptor blockade (1970) (99)
Dynamic aspects of enzymatic O-methylation and -demethylation of catechols in vitro and in vivo. (1960) (99)
Elevation of Serum Dopamine-β-hydroxylase Activity with Forced Immobilization (1971) (98)
AN INHIBITORY EFFECT OF MELATONIN ON THE ESTROUS PHASE OF THE ESTROUS CYCLE OF THE RODENT. (1964) (97)
FATE OF H3-NORADRENALINE IN SKELETAL MUSCLE BEFORE AND FOLLOWING SYMPATHETIC STIMULATION. (1963) (97)
Effect of Psychosocial Stimulation on the Enzymes Involved in the Biosynthesis and Metabolism of Noradrenaline and Adrenaline (1971) (97)
The enzymic acetylation of serotonin and other naturally ocurring amines (1961) (96)
Studies on the storage of norepinephrine and the effect of drugs. (1963) (95)
Evidence for a nonretinal pathway of light to the pineal gland of newborn rats. (1966) (95)
The enzymatic formation of bilirubin glucuronide. (1957) (95)
AGE AND ENZYME ACTIVITY IN THE HUMAN PINEAL. (1964) (94)
Pineal β-Adrenergic Receptor: Diurnal Variation in Sensitivity (1974) (94)
The uptake, storage, release and metabolism of noradrenaline in sympathetic nerves. (1969) (94)
Characterization and substrate specificity of a protein carboxymethylase in the pituitary gland. (1974) (94)
A specific and sensitive enzymatic assay for tryptamine in tissues. (1972) (94)
Circadian rhythm in the serotonin content of the rat pineal gland: regulating factors. (1967) (93)
A Biochemical Lesion in Congenital, Non-obstructive, Non-hæmolytic Jaundice (1957) (93)
A SENSITIVE ASSAY FOR 5-HYDROXYTRYPTOPHAN DECARBOXYLASE. (1964) (91)
The enzymatic demethylation of ephedrine. (1955) (90)
Thyroid function and the cardiac disposition of catecholamines. (1963) (90)
Daily rhythmic changes in tyrosine transaminase activity of the rat liver. (1967) (89)
Differential binding and release of norepinephrine and tachyphylaxis. (1962) (88)
Phospholipid methylation affects immunoglobulin E-mediated histamine and arachidonic acid release in rat leukemia basophils. (1980) (88)
Effect of pituitary and ACTH on the maintenance of basal tyrosine hydroxylase activity in the rat adrenal gland. (1970) (88)
A dimethyltryptamine-forming enzyme in human blood. (1973) (87)
Corticotropin releasing factor stimulates adrenocorticotropin and β-endorphin release from AtT-20 mouse pituitary tumor cells (1982) (86)
Thyrotropin-releasing hormone-like material in the rat retina: changes due to environmental lighting. (1977) (85)
A transduction pathway associated with receptors coupled to the inhibitory guanine nucleotide binding protein Gi that amplifies ATP-mediated arachidonic acid release. (1991) (85)
Subcellualr distribution of protein carboxymethylase and its endogenous substrates in the adrenal medulla: possible role in excitation-secretion coupling. (1976) (84)
Localization of triiodothyronine in nerve ending fractions of rat brain. (1976) (84)
Pineal beta adrenergic receptor: correlation of binding of 3H-l-alprenolol with stimulation of adenylate cyclase. (1976) (84)
Bradykinin stimulates phospholipid methylation, calcium influx, prostaglandin formation, and cAMP accumulation in human fibroblasts. (1983) (84)
Abnormal Storage of Norepinephrine in Experimental Hypertension in the Rat (1967) (83)
Enhanced release of dopamine- -hydroxylase from sympathetic nerves by calcium and phenoxybenzamine and its reversal by prostaglandins. (1971) (82)
Enzymatic p-O-Methylation by Catechol O-Methyl Transferase (1959) (82)
IgE-mediated histamine release in rat basophilic leukemia cells: receptor activation, phospholipid methylation, Ca2+ flux, and release of arachidonic acid. (1981) (82)
Metabolism of 7-H3-epinephrine-d-bitartrate in normal young men. (1961) (82)
Distinct bradykinin receptors mediate stimulation of prostaglandin synthesis by endothelial cells and fibroblasts. (1988) (81)
Estrogen-2-hydroxylase in the rat. Distribution and response to hormonal manipulation. (1980) (81)
Elevated plasma dopamine-beta-hydroxylase activity in autosomal dominant torsion dystonia. (1973) (78)
Beta-adrenergic stimulation of pineal N-acetyltransferase: adenosine 3':5'-cyclic monophosphate stimulates both RNA and protein synthesis. (1975) (78)
Effect of decentralization and ganglionic blocking agents on the spontaneous release of H3-norepinephrine. (1962) (76)
Effect of drugs on the tryptamine content of rat tissues. (1973) (75)
Alpha 1-adrenergic stimulation of arachidonic acid release and metabolism in a rat thyroid cell line. Mediation of cell replication by prostaglandin E2. (1986) (74)
CHANGES IN THE ENZYMATIC SYNTHESIS OF METABOLISM IN THE PINEAL DURING THE ESTROUS CYCLE. (1965) (73)
Inhibition of H3-norepinephrine release by monoamine oxidase inhibitors. (1961) (73)
Phase difference in the induction of tyrosine hydroxylase in cell body and nerve terminals of sympathetic neurones. (1970) (72)
The Pineal Gland and its Endocrine Role (1983) (71)
Prolonged somatostatin pretreatment desensitizes somatostatin's inhibition of receptor-mediated release of adrenocorticotropin hormone and sensitizes adenylate cyclase. (1983) (71)
The accumulation of C14-serotonin in the guinea-pig vas deferens. (1969) (70)
The direct determination of phosphatidyl ethanolamine and phosphatidyl serine in plasma and red blood cells. (1953) (69)
Heterogeneity of N-and O-methyltransferases. (1970) (69)
Enzymatic Formation of Corticosteroid Glucuronides1 (1955) (68)
Induction of dopamine- -hydroxylase and tyrosine hydroxylase in rat hearts and sympathetic ganglia. (1972) (67)
6-Hydroxylation, the major metabolic pathway for melatonin. (1960) (67)
O-Methylation in the conversion of tyrosine to melanin. (1963) (67)
Ascorbic acid in aromatic hydroxylation. III. Effect of ascorbic acid on hydroxylation of acetanilide, aniline and antipyrine in vivo. (1954) (66)
Cholera toxin and pertussis toxin stimulate prostaglandin E2 synthesis in a murine macrophage cell line. (1988) (66)
Phospholipase activation in the IgE-mediated and Ca2+ ionophore A23187-induced release of histamine from rat basophilic leukemia cells. (1981) (65)
Demonstration and distribution of phenylethanolamine in brain and other tissues. (1973) (65)
Association between fighting behavior and catecholamine biosynthetic enzyme activity in two inbred mouse sublines. (1974) (65)
Metabolism of theophylline (1,3-dimethylxanthine) in man. (1952) (65)
On the mechanism of tachyphylaxis to tyramine in the isolated rat heart. (1962) (65)
EFFECTS OF DENERVATION ON THE UPTAKE AND BETA-HYDROXYLATION OF TYRAMINE IN THE RAT SALIVARY GLAND. (1964) (64)
THE DISPOSITION OF CATECHOLAMINES IN THE RAT UTERUS AND THE EFFECT OF DRUGS AND HORMONES. (1964) (64)
Factors affecting the enzymatic formation of O-methylated dihydroxy derivatives. (1965) (64)
Effect of drugs on the accumulation and metabolism of extraneuronal norepinephrine in the rat heart. (1967) (63)
SUBCELLULAR LOCALIZATION OF CATECHOLAMINES IN TISSUES OF THE RAT. (1963) (63)
Catecholestrogen synthesis and metabolism by human breast tumors in vitro. (1979) (63)
Enzymatic methylation of carboxyl groups of chromaffin granule membrane proteins. (1978) (62)
Superinduction of serotonin N-acetyltransferase and supersensitivity of adenyl cyclase to catecholamines in denervated pineal gland. (1973) (62)
Bridging of IgE receptors activates phospholipid methylation and adenylate cyclase in mast cell plasma membranes. (1981) (62)
Formation of Melatonin and 5-Hydroxyindole Acetic Acid from 14C-Tryptophan by Rat Pineal Glands in Organ Culture (1968) (62)
Control of pineal N-acetylserotonin by a beta adrenergic receptor. (1973) (61)
THE FORMATION OF O-METHYLATED CATECHOLS BY MICROSOMAL HYDROXYLATION OF PHENOLS AND SUBSEQUENT ENZYMATIC CATECHOL O-METHYLATION. SUBSTRATE SPECIFICITY. (1965) (61)
Dopamine-β-hydroxylase Activity in the Rat After Hypophysectomy (1970) (60)
Quinacrine-blocked desensitization of adrenoceptors after immobilization stress or repeated injection of isoproterenol in rats. (1981) (60)
Genetic regulation of the catecholamine biosynthetic enzymes. II. Inheritance of tyrosine hydroxylase, dopamine-beta-hydroxylase, and phenylethanolamine N-methyltransferase. (1974) (60)
Variants of the rat basophilic leukemia cell line for the study of histamine release. (1982) (60)
The cloned vasopressin V1a receptor stimulates phospholipase A2, phospholipase C, and phospholipase D through activation of receptor-operated calcium channels (1994) (60)
Activation of beta 2-adrenergic receptors on mouse anterior pituitary tumor cells increases cyclic adenosine 3':5'-monophosphate synthesis and adrenocorticotropin release (1983) (59)
Multireceptor-induced release of adrenocorticotropin from anterior pituitary tumor cells. (1982) (59)
Species differences in inducibility of phenylethanolamine-N-methyl transferase. (1968) (58)
Regulation of sensitivity to beta-adrenergic stimulation in induction of pineal N-acetyltransferase. (1975) (57)
Interleukin 1 potentiates the secretion of beta-endorphin induced by secretagogues in a mouse pituitary cell line (AtT-20). (1989) (57)
Inhibition of tyrosine transaminase activity by norepinephrine. (1969) (57)
Beta-adrenergic mechanism of insulin-induced adrenocorticotropin release from the anterior pituitary. (1984) (56)
Sex differences and hormonal control of histamine methyltransferase activity. (1965) (56)
Estrogen-induced efflux of endogenous catecholamines from the hypothalamus in vitro (1979) (56)
S-DEMETHYLATION BY MICROSOMAL ENZYMES. (1964) (56)
METABOLISM AND DISPOSITION OF TETRAHYDROCANNABINOLS IN NÄIVE SUBJECTS AND CHRONIC MARIJUANA USERS (1971) (56)
CONTROL OF 5-HYDROXYTRYPTOPHAN DECARBOXYLASE ACTIVITY IN THE RAT PINEAL GLAND BY SYMPATHETIC NERVES. (1965) (56)
Enzymatic Synthesis of the Skin-lightening Agent, Melatonin, in Amphibians (1965) (55)
Increased rate of metabolism of epinephrine and norepinephrine by sympathomimetic amines. (1960) (55)
Direct stimulation of beta 2-adrenergic receptors in rat anterior pituitary induces the release of adrenocorticotropin in vivo. (1983) (54)
ENZYMIC OXIDATION OF EPINEPHRINE TO ADRENOCHROME BY THE SALIVARY GLAND. (1964) (54)
The effect of estradiol on catechol-O-methyltransferase activity in rat liver. (1971) (54)
EFFECTS OF COLCHICINE AND VINBLASTINE ON AXONAL TRANSPORT AND TRANSMITTER RELEASE IN SYMPATHETIC NERVES (1975) (54)
Relationship between Serum Dopamine‐β‐Hydroxylase Activity, Catecholamine Metabolism, and Hemodynamic Changes during Paroxysmal Hypertension in Quadriplegia (1974) (53)
A transfected m5 muscarinic acetylcholine receptor stimulates phospholipase A2 by inducing both calcium influx and activation of protein kinase C. (1990) (53)
Mediation of Some Effects of Illumination on the Rat Estrous Cycle by the Sympathetic Nervous System (1964) (52)
Genetically controlled alterations in the rate of degradation of phenylethanolamine N-methyltransferase. (1973) (51)
Phospholipid metabolism, calcium flux, and the receptor-mediated induction of chemotaxis in rabbit neutrophils (1982) (51)
Synthesis of Serotonin by Pineal Glands of the Rat in Organ Culture (1967) (50)
Long-term synaptic transformation of hippocampal CA1 gamma-aminobutyric acid synapses and the effect of anandamide. (1995) (50)
THE FORMATION, METABOLISM, AND PHYSIOLOGIC EFFECTS OF MELATONIN IN MAMMALS. (1965) (50)
Interleukin 1 induces beta-endorphin secretion via Fos and Jun in AtT-20 pituitary cells. (1990) (50)
Evidence for the presence of monoamine oxidase in sympathetic nerve endings (1965) (49)
Neuronally dependent induction of adrenal phenylethanolamine-N-methyltransferase by 6-hydroxydopamine. (1970) (49)
Evidence for two methyltransferase involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in the rat liver. (1981) (48)
α1‐Adrenergic Receptor Mediates Arachidonic Acid Release in Spinal Cord Neurons Independent of Inositol Phospholipid Turnover (1990) (48)
A SENSITIVE ENZYMATIC‐ISOTOPIC METHOD FOR THE ANALYSIS OF TYRAMINE IN BRAIN AND OTHER TISSUES (1976) (48)
The fate of papaverine in man and other mammals. (1958) (48)
Subcellular localization of monoamine oxidase in rat tissues. (1969) (47)
Cannabinoid Receptors and Their Endogenous Agonist, Anandamide (1998) (46)
Evidence for estradiol binding sites in the hypothalamus-effect of drugs. (1967) (46)
Stimulation of phospholipase A 2 activity in bovine rod outer segments by the 18 y subunits of transducin and its inhibition by the a subunit (46)
Enzymatic Synthesis of N-Glucuronic Acid Conjugates (1957) (46)
Enzymatic carboxymethylation of the nicotinic acetylcholine receptor. (1980) (45)
Protein Carboxyl Methylation Increases in Parallel With Differentiation of Neuroblastoma Cells (1983) (45)
Phorbol esters and diacylglycerols amplify bradykinin-stimulated prostaglandin synthesis in Swiss 3T3 fibroblasts. Possible independence from protein kinase C. (1988) (45)
Studies on sympathomimetic amines. I. The biotransformation and physiological disposition of l-ephedrine and l-norephedrine. (1953) (45)
The Uptake and Release of Catecholamines and the Effect of Drugs (1964) (45)
Estimation of Dicumarol, 3, 31-Methylenebis (4-Hydroxycoumarin) in Biological Fluids.* (1949) (45)
Tyrosine hydroxylase and dopamine‐β ‐hydroxylase: distribution in the individual rat hypothalamic nuclei (1974) (44)
Increased Monoamine Oxidase Activity during the Development of Cardiac Hypertrophy in the Rat (1968) (43)
Relationship between catecholamines and other hormones. (1975) (43)
The enzymatic conversion of codeine to morphine. (1955) (43)
The metabolism of catecholamines in vivo and in vitro. (1959) (42)
METABOLISM AND DISPOSITION OF Δ9-TETRAHYDROCANNABINOL IN MAN (1971) (42)
Photic and neural control of indoleamine metabolism in the rat pineal gland. (1968) (42)
EVIDENCE FOR EXTRANEURONAL BINDING OF NOREPINEPHRINE. (1965) (42)
Relation Between the Œstrous Cycle and the Binding of Catecholamines in the Rat Uterus (1963) (41)
Release of Tritiated Epinephrine following Sympathetic Nerve Stimulation (1964) (41)
Actions of cocaine and tyramine on the uptake and release of H3-norepinephrine in the heart. (1961) (41)
Biosynthesis and metabolism of endogenous tyramine and its normal presence in sympathetic nerves. (1976) (41)
CONTROL OF THE CIRCADIAN RHYTHM IN SEROTONIN CONTENT OF THE RAT PINEAL GLAND. (1964) (41)
LOCALIZATION OF NOREPINEPHRINE IN ADRENERGIC AXONS BY LIGHT- AND ELECTRON-MICROSCOPIC AUTORADIOGRAPHY (1962) (41)
SEX STEROIDS, CARDIAC 3H-NOREPINEPHRINE, AND TISSUE MONOAMINE OXIDASE LEVELS IN THE RAT. (1963) (40)
Enzymatic N-Methylation of Histamine (1959) (40)
ENZYMATIC FORMATION OF O-METHYLATED DIHYDROXY DERIVATIVES FROM PHENOLIC AMINES AND INDOLES. (1965) (39)
Regulation of rat adrenal dopamine β-hydroxylase. II. Receptor interaction in the regulation of enzyme synthesis and degradation (1976) (39)
Catecholamines and hypertension. (1976) (38)
[101b] Catechol-O-methyl transferase from rat liver: (1962) (38)
Abnormal Cardiac Norepinephrine Storage in Isoproterenol‐Treated Rats (1968) (38)
DEVELOPMENTAL CHARACTERISTICS OF PHENYLETHANOLAMINE AND OCTOPAMINE IN THE RAT BRAIN (1974) (38)
Hydroxyindole-O-methyltransferase in several avian species. (1968) (38)
EVIDENCE FOR EXTRANORADRENERGIC DOPAMINE‐β‐HYDROXYLASE ACTIVITY IN RAT SALIVARY GLAND (1974) (38)
Beta adrenergic stimulation of protein carboxymethylation and amylase secretion in rat parotid gland. (1978) (38)
Regional differences in dopamine-mediated release of TRH-like material from synaptosomes (1977) (37)
Protein carboxymethylation: effects of 2% sodium chloride administration on protein carboxymethylase and its endogenous substrates in rat posterior pituitary. (1978) (37)
Activation and Inhibition of Adrenaline Metabolism (1959) (37)
The inhibitory action of nalorphine on the enzymatic N-demethylation of narcotic drugs. (1957) (36)
The physiologic disposition of H3-histamine in the rat brain. (1966) (36)
Protein methylesterase and leukocyte chemotaxis. (1980) (36)
A reduction in the accumulation of H3-norepinephrine in experimental hypertension. (1966) (36)
Phospholipase A2 and G proteins (1995) (36)
Rat basophilic leukemia cell lines defective in phospholipid methyltransferase enzymes, Ca2+ influx, and histamine release: reconstitution by hybridization. (1981) (36)
Light-Induced Changes in Pineal Hydroxyindole-O-Metthyltransferase: Abolition by Lateral Hypothalamic Lesions (1966) (35)
Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids. (1967) (35)
THE STORAGE OF NOREPINEPHRINE AND SOME OF ITS DERIVATIVES IN BRAIN SYNAPTOSOMES. (1965) (34)
Catecholamines and methyltransferases in the South American toad (Bufo marinus). (1962) (34)
A SENSITIVE ENZYMATIC‐RADIOISOTOPIC ASSAY FOR 3,4‐DIHYDROXYPHENYLACETIC ACID (1977) (34)
Dopaminergic neurons in explants of substantia nigra in culture. (1973) (33)
Enzymatic methylation of the membrane-bound nicotinic acetylcholine receptor. (1982) (33)
Diurnal variation in the requirement for RNA synthesis in the induction of pineal N-acetyltransferase. (1976) (33)
Subcellular localization of H3-norepinephrine in the rat brain and the effect of drugs. (1966) (33)
METHYLATION AND DEMETHYLATION IN RELATION TO THE IN VITRO METABOLISM OF MESCALINE (1962) (33)
Increased biosynthesis of cardiac norepinephrine after hypophysectomy. (1969) (33)
Demonstration of Hydroxyindole-O-methyl Transferase, Melatonin, and Serotonin in a Metastatic Parenchymatous Pinealoma (1964) (32)
Induction of adrenal tyrosine hydroxylase in organ culture. (1972) (32)
Studies on the Metabolism of Catecholamines (1961) (32)
THE ROLE OF MONOAMINE OXIDASE IN THE RELEASE AND METABOLISM OF NOREPINEPHRINE (1963) (31)
Changes in phospholipid methyltransferases and membrane microviscosity during induction of rat liver microsomal cytochrome P-450 by phenobarbital and 3-methylcholanthrene. (1981) (31)
Phenol-O-methyltransferase. (1968) (31)
Interaction of neuropeptides and biogenic amines on cyclic adenosine monophosphate accumulation in hypothalamic nuclei (1986) (31)
The regulation of pineal serotonin by a beta adrenergic receptor. (1973) (31)
The fate of dibenzyline in the body and the role of fat in its duration of action. (1954) (31)
The formation, metabolism and physiologic effects of melatonin. (1968) (30)
Incorporation of 14C-tryptophan into 14C-protein by cultured rat pineals: stimulation by l-norepinephrine. (1969) (30)
N-Methyladrenaline, a new catecholamine in the adrenal gland. (1960) (30)
Inhibition of phenylethanolamine-N-methyl transferase. (1967) (29)
Hypothalamic regulation of the daily rhythm in hepatic tyrosine transaminase activity. (1971) (29)
Reduced Uptake of Tritiated Noradrenaline in Tissues of Immunosympathectomized Animals (1965) (29)
The biosynthesis of octopamine (2004) (29)
Inhibition by Drugs of the Accumulation in vitro of 5-Hydroxytryptamine in Guinea-pig Vas Deferens (1968) (29)
Journey of a Late Blooming Biochemical Neuroscientist (2003) (29)
SOME CLINICAL, BIOCHEMICAL, AND PHYSIOLOGICAL ACTIONS OF THE PINEAL GLAND. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH. (1964) (28)
The fate of noradrenaline in the sympathetic neurone. (1973) (28)
STIMULATION OF SEROTONIN N‐ACETYLTRANSFERASE IN PINEAL ORGAN CULTURE BY DRUGS (1974) (28)
The relationship between phospholipid methylation and calcium influx in murine lymphocytes stimulated with native and modified Con A. (1982) (28)
Elevation and depression of hepatic tyrosine transaminase activity by depletion and repletion of norepinephrine. (1968) (28)
Relationship between catecholamines and serotonin in sympathetic nerves of the rat pineal gland. (1969) (28)
Protein carboxymethylase and methyl-acceptor proteins in human platelets and erythrocytes. (1978) (27)
Neural and Photic Regulation of 5-Hydroxytryptophan Decarboxylase in the Rat Pineal Gland (1964) (27)
Inhibitors of the cytochrome P-450 enzymes block the secretagogue-induced release of corticotropin in mouse pituitary tumor cells. (1985) (27)
Protein carboxyl-methylation in rat testes: a study of inherited and X-ray-induced seminiferous tubule failure. (1979) (27)
Phospholipid methylation and human platelet function. (1981) (26)
Muscarinic receptors mediate the release of arachidonic acid from spinal cord and hippocampal neurons in primary culture (1990) (26)
Catechol estrogens: presence in brain and endocrine tissues. (1977) (26)
Metabolism of Lysergic Acid Diethylamide (1956) (25)
Use of N-Acetyl 4-Aminoantipyrine (NAAP)∗ in Measurement of Total Body Water (1951) (25)
Suppression of the Daily Rhythm in Tyrosine Transaminase Activity by Acute Elevation of Norepinephrine (1968) (25)
Peripheral and central catecholaminergic neurons in genetic and experimental hypertension in rats. (1976) (25)
SUBCELLULAR LOCALIZATION OF PROTEIN CARBOXYL‐METHYLASE AND ITS SUBSTRATES IN RAT PITUITARY LOBES (1979) (25)
Corticotropin releasing factor stimulation of protein carboxylmethylation in mouse pituitary tumor cells. (1983) (24)
A rapid and sensitive radioenzymatic assay for catechol estrogens in tissues. (1977) (24)
Neurally Mediated Increase in Dopamine-fl-Hydroxylase Activity (23)
Inhibition of the Extraneuronal Metabolism of Noradrenaline in the Isolated Heart by Adrenergic Blocking Agents (1967) (23)
Reduced accumulation of 3H-norepinephrine in the rat heart following hypophysectomy. (1968) (23)
Interleukin 1 induces early protein phosphorylation and requires only a short exposure for late induced secretion of beta-endorphin in a mouse pituitary cell line. (1990) (22)
Metabolism and disposition of delta-9-tetrahydrocannabinol in man. (1971) (22)
The physiological disposition and biotransformation of dibenamine and a method for its estimation in biological tissues. (1952) (21)
Electrophoretic properties of dopamine -hydroxylase in several tissues from three species. (1972) (21)
The Metabolism of the Catecholamines (Clinical Implications): Combined Clinical Staff Conference of the National Institutes of Health (1962) (21)
Corticotropin-releasing factor stimulates phospholipid methylation and corticotropin secretion in mouse pituitary tumor cells. (1982) (21)
The enzymatic formation of catecholestrogens from 2-methoxyestrogens by rat liver microsomes. (1980) (21)
adivation of phospholipase Az via GTP- binding proteins: arachidonic acid and its metabolites as second messengers (1988) (20)
Presence of 3-Methoxy-4-hydroxyphenylglycol and Metanephrine in Phæochromocytoma Tissue (1960) (20)
Distribution of the Adrenaline-forming Enzyme in the Adrenal Gland of a Snake, Xenodon merremii (1967) (20)
THE RELATION BETWEEN MELATONIN, A PINEAL SUBSTANCE, AND THE EFFECTS OF LIGHT ON THE RAT GONAD (1964) (20)
Regulation of the daily rhythm in tyrosine transaminase activity by environmental factors. (1968) (19)
Regulation of the beta-adrenergic receptor by methylation of membrane phospholipids. (1981) (19)
Studies on the Chemical and Enzymatic Oxidation of Lysergic Acid Diethylamide1 (1957) (19)
LOCALIZATION OF EXTRANEURONAL DOPAMINE‐β‐HYDROXYLASE IN RAT SALIVARY GLAND BY IMMUNOFLUORESCENCE HISTOCHEMISTRY (1975) (19)
The disposition and metabolism of tryptamine and the in vivo formation of 6-hydroxytryptamine in the rabbit. (1971) (19)
INHIBITION OF HISTAMINE METHYLATION IN VIVO BY DRUGS. (1964) (19)
Enhancement of H-3-norepinephrine uptake in rat tissues by O-methylated metabolites of catecholamines. (1966) (18)
Effect of Chlorpromazine and Other Drugs on the Disposition of Circulating Melatonin (1966) (18)
[The fate of benzazoline (priscoline) in dog and man and a method for its estimation in biological material]. (1952) (17)
Glucuronide Formation of Narcotic Drugs in vitro and in vivo (1960) (17)
UTERINE EPINEPHRINE AND BLOOD FLOW IN PREGNANT AND POSTPARTURIENT RATS. (1963) (17)
3,4-Dihydroxyphenylglycol, a metabolite of epinephrine. (1960) (17)
Octopamine as a putative neurotransmitter. (1976) (17)
Medial forebrain bundle lesions: blockade of effects of light on rat gonads and pineal. (1967) (16)
A daily rhythm in the rate of depletion of brain norepinephrine by reserpine. (1969) (16)
The pineal gland: a biological clock. (1966) (16)
Catecholamine Neurotransmitters, Psychoactive Drugs, and Biological Clocks (1981) (16)
Phospholipid methylation and the transmission of biological signals through membranes (1980) (16)
Enzymatic synthesis of N-glucosyluronic acid conjugates. (1958) (16)
Biochemical and morphologic study of catecholamine metabolism in spontaneously hypertensive rats. (1977) (15)
The effects of ligands on enzymic carboxyl-methylation of neurophysins. (1976) (15)
Brain tryptamine and the effects of drugs. (1974) (15)
Lectin-induced mitosis and phospholipid methylation. (1982) (15)
Neuronal and Hormonal Control of Tyrosine Hydroxylase and Phenylethanolamine N-Methyltransferase Activity (1970) (15)
TISSUE METABOLISM OF HISTAMINE -C14 IN VIVO. (1965) (14)
The fate of norepinephrine and the effect of drugs. (1968) (14)
THE PHYSIOLOGICAL DISPOSITION OF C14-SEROTONIN IN THE RAT UTERUS. (1964) (14)
Concepts in Biochemical Pharmacology (1971) (14)
Regulation of the Neurotransmitter Norepinephrine (1974) (14)
Muscarinic Acetylcholine Receptor Subtypes Associated with Release of Alzheimer Amyloid Precursor Derivatives Activate Multiple Signal Transduction Pathways (1993) (14)
The fate of acetophenetidin in man and methods for the estimation of acetophenetidin and its metabolites in biological material. (1949) (14)
Introductory remarks on regulation of pineal indoleamine synthesis. (Chairman's introduction). (1978) (14)
Interleukin-1 potentiation of β-endorphin secretion and the dynamics of interleukin-1 internalization in pituitary cells (1991) (14)
The possible functional significance of phosphatidylethanolamine methylation: Reply from J. Axelrod and F. Hirata (1980) (13)
Enzymic conversion of metanephrine to epinephrine. (1958) (13)
Perspectives in neuropharmacology : a tribute to Julius Axelrod (1972) (13)
Methyltransferase Enzymes in the Metabolism of Physiologically Active Compounds and Drugs (1971) (12)
Studies of a methionine-activating enzyme. (1972) (12)
The formation, metabolism and some actions of melatonin, a pineal gland substance. (1966) (12)
Phospholipid methylation: a possible mechanism of signal transduction across biomembranes. (1981) (12)
Elevation of serum dopamine-beta-hydroxylase activity with forced immobilization. (1971) (12)
Increased monoamine oxidase activity in isoproterenol-stimulated submaxillary glands. (1968) (12)
Hydroxylation and N-demethylation of N,N-dimethyltryptamine (1959) (12)
[243c] Histamine-N-methyltransferase (Pig liver) (1971) (12)
Phospholipid methylation and the receptor-induced release of histamine from cells (1982) (12)
Inhibition of the metabolism of H3-melatonin by phenothiazines. (1968) (11)
Observations on the fate of dromoran in the dog and its secretion into the gastric juice. (1955) (11)
Substrate and inhibitor kinetics of bovine phenylethanolamine-N-methyltransferase. (1975) (11)
Comparative Biochemistry of the Pineal Gland (1970) (11)
The exzymic acetylation of serotonin and other naturally occurring amines. (1961) (11)
Adrenergic regulation of beta-endorphin secretion from anterior pituitary in conscious rats: effects of thyroid state. (1987) (11)
Desensitization of beta 2-adrenergic receptors and adrenocorticotropin release. (1983) (11)
A Deficient Binding Mechanism for Norepinephrine in Hearts of Scorbutic Guinea Pigs (1966) (11)
METABOLISM AND INACTIVATION OF NORADRENALINE AND ADRENALINE AND THE EFFECT OF DRUGS (1965) (10)
The discovery of the microsomal drug-metabolizing enzymes (1982) (10)
Effect of Drugs on Amine Uptake Mechanisms in the Brain (1970) (10)
ROLE OF β-ADRENERGIC RECEPTOR IN THE CONTROL OF SEROTONIN N-ACETYLTRANSFERASE IN RAT PINEAL (1973) (10)
Biochemical factors in the activation and inactivation of drugs (2004) (9)
EFFECTS OF DEXAMETHASONE ON NEUROTRANSMITTER ENZYMES IN CHROMAFFIN TISSUE OF THE NEWBORN RAT (1975) (9)
CHAPTER 4 – The Regulation of Some Biochemical Circadian Rhythms (1970) (9)
Pineal beta-adrenergic receptor: diurnal variation in sensitivity. (1974) (9)
ROLE FOR METHYLATION IN LEUKOCYTE CHEMOTAXIS (1979) (9)
Regulation of Circadian Rhythms of Indoleamines in the Pineal Gland (1983) (9)
Transmission and regulation of triggering signals induced by bridging of IgE receptors on rat mast cells. (1981) (9)
Studies on benzodiazepine receptors. (1980) (8)
Biphasic effect of norepinephrine in the regulation of hepatic tyrosine transaminase activity. (1970) (8)
CONTROL OF CATECHOLAMINE AND INDOLEAMINE METABOLISM BY SYMPATHETIC NERVES (1966) (8)
Triiodothyronine in rat submaxillary salivary gland: effects of altered adrenergic function. (1977) (8)
Enzymatic-isotopic micromethods for the measurement of biogenic amines in brain tissue and body fluids. (1974) (7)
Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3 T 3 fibroblasts : Evidence for G protein regulation of phospholipase A 2 ( arachidonic acid / glucocorticoids / protein kinase C ) (7)
THE ENZYMATIC DEAMINATION OF AMPHETAMINE (2003) (7)
Phospholipase A 2 and phospholipase C are activated by distinct GTP-binding proteins in response to a 1-adrenergic stimulation in FRTL 5 thyroid cells ( arachidonic acid / inositol phosphate / intracellular calcium / pertussis toxin / protein kinase C ) (6)
The enzymic conversion of adenine to 3-methyladenine. (1962) (6)
Formation of alpha-methyldopamine ("Catecholamphetamine") from p-hydroxyamphetamine by rat brain microsomes. (1979) (6)
Stress, the role of catecholamines and other neurotransmitters : proceedings of the Third International Symposium on Catecholamines and Other Neurotransmitters in Stress, Smolenice Castle, Czechoslovakia, June 7-12, 1983 (1984) (6)
The physiologic effects of melatonin and the control of its biosynthesis. (1966) (6)
18. Cellular adaptation in the development of tolerance to drugs. (1968) (6)
Regulation of beta-adrenergic receptors by phospholipid methylation. (1980) (6)
Formation of Methanol by an Enzyme in an Ectopic Pinealoma (1967) (6)
Interleukin I potentiates agonist-induced secretion of β-endorphin in anterior pituitary cells (1990) (5)
Factors affecting the metabolism of epinephrine and other amines. (1962) (5)
RINGDEHYDROXYLATION AND N-METHYLATION OF NORADRENALINE AND DOPAMINE IN THE INTACT RAT BRAIN (1973) (5)
Phospholipid methylation and receptor-mediated transmission of biological signals through membranes (1981) (5)
Biochemical pharmacology of catecholamines and its clinical implications. (1971) (5)
CONTROL OF β-ADRENERGIC RECEPTORS IN HELA CELLS (1979) (5)
BIOCHEMICAL FACTORS IN THE FORMATION OF ACTIVE AND TOXIC METABOLIC PRODUCTS (1965) (4)
DEVELOPMENTAL ASPECTS OF CATECHOLESTROGEN SYNTHESIS (1981) (4)
The sympathochromaffin system and the pituitary-adrenocortical response to hypoglycemia. (1986) (4)
Dopamine-beta-hydroxylase activity in the rat after hypophysectomy. (1970) (4)
Increased serum dopamine-β-hydroxylase activity during neurogenic hypertension in quadriplegia (1974) (4)
Trans-synaptic induction of dopamine (3,4-dihydroxyphenethylamine) -hydroxylase in adrenergic tissues of the rat. (1971) (4)
Alpha-1 adrenergic receptor mediates the release of arachidonic acid in spinal cord neurons independent of phosphatidylinositol-specific phospholipase C. (1990) (4)
The effect of elevated temperature on the retention of 3H-norepinephrine in the hearts of normal and thyroidectomized rats. (1968) (4)
Phospholipid methyltransferase asymmetry in synaptosomal membranes (1980) (4)
PHARMACODYNAMICS OF HUMAN DISEASE. 1. BIOCHEMICAL FACTORS IN THE ACTION OF ANALGESIC AND NARCOTIC DRUGS. (1963) (3)
Interleukin-1 amplifies the action of pituitary secretagogues via protein kinases. (1990) (3)
Wrong move (1995) (3)
Regulation of Dopamine @-Hydroxylase in Rat Adrenal Glands (2003) (3)
Receptor Mediated Activation of Phospholipase A2: Arachidonic Acid and its Metabolites as Second Messengers (1987) (3)
Stress : neuroendocrine and molecular approaches : proceedings of the Fifth International Symposium on Catecholamines and Other Neurotransmitters in Stress, Smolenice Castle, Czechoslovakia, 24-29 June, 1991 (1992) (3)
PHOSPHOLIPID METHYLATION, MEMBRANE FLUIDITY AND COUPLING OF THE β-ADRENERGIC RECEPTOR (1979) (3)
CHAPTER 2 - Receptor-mediated activation of phospholipase A2 (1990) (3)
Effects of Melatonin, a Pineal Substance, on the Rat Ovary. (1963) (3)
Catecholamine neurotransmitters, psychoactive drugs, and biological clocks. The 1981 Harvey Cushing oration. (1981) (3)
Corticotropin releasing factor stimulates adrenocorticotropin and beta-endorphin release from AtT-20 mouse pituitary tumor cells. (1982) (3)
Octopamine, Phenylethanolamine, Phenylethylamine and Tryptamine in the Brain (2008) (2)
Effect of gonadal hormones on aromatic amino acid decarboxylase in the rat uterus. (1966) (2)
[243a] Phenylethanolamine-N-methyltransferase (Mammalian adrenal glands) (1971) (2)
The toxicity of wax crayons in animals. (1948) (2)
Nonstriatal dopaminergic neurons: Section I. Mesocortical dopaminergic neurons: Introduction: mesocortical dopaminergic neurons. (1977) (2)
Pre- and Postsynaptic Regulation of Catecholamine Neurotransmitters (1979) (2)
Regulation of the β-Adrenergic Receptor in the Pineal Gland and Red Cell Membranes (1979) (2)
Alterations in norepinephrine storage in inbred rats made hypertensive by triiodothyronine and sodium chloride. (1971) (2)
THE NORMAL OCCURRENCE OF TRYPTAMINE IN BRAIN AND ITS CONVERSION TO N-METHYL AND N-DIMETHYLTRYPTAMINE IN VITRO AND IN VIVO (1973) (2)
Secretagogues elevate cytosolic calcium by stimulating cyclic AMP formation in a corticotropin secreting cell line. (1985) (2)
THE PINEAL GLAND. (1965) (2)
Rat basophilic leukemia cell lines defective in phospholipid methyltransferase enzymes: Reconstitution by hybridization of IgE-mediated Ca 2+ influx, phospholipid methylation and histamine release (1982) (2)
Bradykinin receptor stimulation of cAMP involves phospholipid methylation, Ca flux, phospholipase A2 activation and prostaglandin formation (1981) (2)
Raipid stimulation of protein carboxymethylation in leukocytes by a chemotatic peptide. (1978) (2)
Neural and hormonal control of catecholamine synthesis. (1972) (2)
Enzymatic conversion of metanephrine to normetanephrine (1960) (2)
Estimation of O-methylated metabolites of catecholamines. (1961) (1)
Neural Control of Indoleamine Metabolism in the Pineal (2008) (1)
CARBACHOL STIMULATION CAUSES INHIBITION OF MITOGENESIS AND CELL ELONGATION IN CHO CELLS TRANSFECTED WITH MUSCARINIC RECEPTOR GENES (1989) (1)
7 – Regulation of ACTH Secretion and Synthesis (1987) (1)
The effect of thyroid and estrogen on the fate of catecholamines. (1966) (1)
Inhiition of neuronally induced tyrosine hydroxylase by nitinic receptor blockade. (1970) (1)
2726 – REGULATION OF CATECHOLAMINE NEUROTRANSMITTERS, METABOLISM AND β-ADRENERGIC RECEPTORS (1978) (1)
Lipids and the Receptor Mediated Release of Histamine (1982) (1)
The physiological disposition of acetophenetidin in man. (1948) (1)
Interleukin 1 potentiates agonist-induced secretion of beta-endorphin in anterior pituitary cells. (1990) (1)
Relation between blockade of H3-noradrenaline uptake and pharmacological actions produced by phenothiazine derivatives (1963) (1)
The clinician and the biologic clock. (1968) (1)
370 Demethylation and Methylation of Drugs and Physiologically Active Compounds (1961) (1)
Physiological Disposition of 2-Phenyl Quinoline-4-Carboxylic Acid (Ginchophen) in Man. Method for its Estimation in Biological Material (1954) (1)
Melatonin Synthesis in the Pineal Gland: Effect of Light Mediated by the Sympathetic Nervous System. (1964) (0)
The Fate of Catecholamines and Its Impact in Psychopharmacology (1985) (0)
RELATIONSHIP BETWEEN β-ADRENERGIC RECEPTOR AND SPECIFIC MYOCARDIAL PROTEIN SYNTHESIS (1979) (0)
activity may be of importance following administration of other drugs as well as monoamine oxidase inhibitors, after development of tachyphylaxis to sympathomi- (1964) (0)
Beta-Adrenergic Stimulation of Pineal N-Acetyltransferase : Adenosine 3 ' : 5 '-Cyclic Monophosphate Stimulates Both RNA and Protein Synthesis ( actinomycin D / circadian rhythms / catecholamine neurotransmitters / arylamine acetyltransferase ) (0)
STUDIES ON SYMPATHOMIMETIC AMINES. II. THE UIc~‘l’I’,A3-S- FOltMATION AND PHYSIOLOGICAL DISPOSITIOK OF D-Aiil- PHETAMIKE, D-P-HYDROXYAiLlPHETAMINE AND D-METH- AMPHETAMINE (2000) (0)
Metabolism of N[or]A[drenaline] (1957) (0)
Caffeine Analysis of Various Commercial Brands of Soluble Coffee (1950) (0)
Drugs as tools in biomedical research. (1970) (0)
Inhibitors of the cytochrome P-450 induced release of corticotropin in (2016) (0)
Interleukin 1amplifies receptor-mediated activation of phospholipase A2in3T3fibroblasts (signal transduction/prostaglandin/bradykinin/thrombin/bombesin) (1988) (0)
Anandamide, anendogenous cannabimimetic eicosanoid, bindsto thecloned humancannabinoid receptor andstimulates (1993) (0)
ESTROGEN DEPENDENT EFFLUX OF ENDOGENOUS CATECHOLAMINES FROM THE HYPOTHALAMUS IN VITRO (1979) (0)
Fate of norepinephrine in sympathetic nerons and by cardiovascular drugs. (1968) (0)
ME,'TABOLISM OF 7-H3-El'INE'HRI1 NIE-d-BLITAiTRltA''ATE IN NORMNAL YOUNG MEN (1960) (0)
The effect of concanavalin A on phospholipid methylation in murine splenic lymphocytes (1979) (0)
The fate of acetanilide in the body. (1947) (0)
Incorporation of super 14 C-tryptophan into super 14 C-protein by cultured rat pineals - Stimulation by 1-norepinephrine. (1969) (0)
egu 1 ation of the Neurotransmitter Norepinephrine (0)
Catecholamines and hyper tension (0)
Cannabinoids as antioxidants and neuroprotective agent (1999) (0)
Mepacrine blocks f 3-adrenergic agonist-induced desensitization in astrocytoma cells ( P-adrenergic receptors / methylation / phospholipids / phospholipase inhibition ) (0)
Phospholipid methylation and beta adrenergic receptors in HeLa cells (1979) (0)
Monograph on Noradrenaline (1967) (0)
Phospholipid methylation: Abiochemical signal modulating lymphocyte mitogenesis (arachidonic acid/prostaglandins/concanavalin A/methylation inhibition) (1980) (0)
Bradykinin stimulates phospholipid methylation, calcium influx, prostaglandin formation, andcAMPaccumulation in (1983) (0)
Corticotropin-releasing factor stimulates phospholipid methylation and corticotropin secretion in mouse pituitary tumor cells ( corticotropin-releasing factor analogues / methyltransferase / adrenocorticotropic hormone ) (0)
Science the Pineal Gland: a Neurochemical Transducer (0)
1-(3′-methoxy-4′-hydroxy benzyl) 6–7 dimethoxy isoquinoline, a major metabolite of papaverine (1957) (0)
Phospholipid methylation: A possible biochemical event in signal transduction (1979) (0)
INTERACTIONS OF INTERLEUKIN 1 WITH PITUITARY CELLS (1992) (0)
Studies of catecholamine metabolism in two hereditary forms of dystonia. (1973) (0)
Distribution of biogenic amines in the rat hypothalamus (1974) (0)
INCORPORATION OF 14 C-TRYPTOPHAN INTO 14 C-PROTEIN BY CULTURED RAT PINEALS : STIMULATION BY 1-NOREPINEPHRINE (2004) (0)
[243] Methyltransferase enzymes in biogenic amine metabolism (1971) (0)
Fate of the neurotransmitter noradrenaline and regulation of its biosynthesis. (1972) (0)
Serotonin stimulates phospholipase A 2 and the release of arachidonic acid in hippocampal neurons by a type 2 serotonin receptor that is independent of inositolphospholipid hydrolysis ( phorbol ester / lysophosphatidylcholine / extracellular calcium ) (0)
f 3-Adrenergic receptor agonists increase phospholipid methylation , membrane fluidity , and fl-adrenergic receptor-adenylate cyclase coupling ( membrane translocation / fluidity / S-adenosylmethionine / reticulocytes ) (0)
JEROME A. ROTH AND C. N. GILLIS. Some Structural Requirements for Inhibition of Type A and B Forms of Rabbit Monoamine Oxidase by Tricyclic Psychoactive (1975) (0)
ENZYMATIC FORMATION OF URIDINE (2003) (0)
Biochemical mechanism of histamine release from rat mast cells and basophilic leukemia cells (1982) (0)
Biochem.ical and Pharm.acological Approaches in the Study of Sym.pathetic Nerves (1992) (0)
The Metabolism of the Catecholamines (Clinical Implications) (2020) (0)
[Sympathetic control of catecholamine and indolamine metabolism]. (1966) (0)
MEDIATION OF SOME EFFECT OF ILLUMINATION ON THE RAT ESTROUS CYCLE BY THE SYMPATHETIC NERVOUS SYSTEM. (1964) (0)
[243b] Hydroxyindole-O-methyltransferase (Bovine pineal gland) (1971) (0)
Biochemical and Pharmacological Approaches in the Study of Sympathetic Nerves (1992) (0)
The Fate of Adrenaline and Noradrenaline (2008) (0)
Inhibition of the metabolism of H super 3 -melatonin by phenothiazines. (1968) (0)
The control of indole metabolism in the rat pineal gland by a β adrenergic receptor (1973) (0)
ENZYMATIC-ISOTOPIC MICROMETHODS FOR THE MEASUREMENT OF BIOGENIC AMINES IN BRAIN TISSUE AND BODY FLUIDS (1975) (0)
Regulation of Sensitivity to β-Adrenergic Stimulation in the Rat Pineal (1978) (0)
Enzymatic Formation of Dopamine. Norepi[nephrine] & Epi[nephrine] (1962) (0)

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