Jan Blatný
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Czech physician
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Jan Blatný's Degrees
- Masters Medicine Charles University
- PhD Medical Ethics Charles University
Why Is Jan Blatný Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jan Blatný is a Czech physician, teacher and politician. On 29 October 2020 he was named as Minister of Health of the Czech Republic by Prime Minister Andrej Babiš following the resignation of Roman Prymula. On 7 April 2021 he was replaced by Petr Arenberger.
Jan Blatný's Published Works
Published Works
- I-path analysis (1993) (742)
- Construction and use of a versatile set of broad-host-range cloning and expression vectors based on the RK2 replicon (1997) (260)
- Improved broad-host-range RK2 vectors useful for high and low regulated gene expression levels in gram-negative bacteria. (1997) (178)
- A new gene required for cellulose production and a gene encoding cellulolytic activity in Acetobacter xylinum are colocalized with the bcs operon (1994) (164)
- A large kindred with X‐linked neutropenia with an I294T mutation of the Wiskott‐Aldrich syndrome gene (2009) (92)
- New broad-host-range promoter probe vectors based on the plasmid RK2 replicon. (2001) (89)
- Prophylactic treatment of haemophilia patients with inhibitors: clinical experience with recombinant factor VIIa in European Haemophilia Centres (2007) (89)
- Characterization of Airborne Bacteria at an Underground Subway Station (2012) (87)
- Detection of Vibrio cholerae by Real-Time Nucleic Acid Sequence-Based Amplification (2007) (87)
- Effects of winter military training on energy balance, whole-body protein balance, muscle damage, soreness, and physical performance. (2014) (74)
- Comparative Testing and Evaluation of Nine Different Air Samplers: End-to-End Sampling Efficiencies as Specific Performance Measurements for Bioaerosol Applications (2014) (72)
- Tracking airborne Legionella and Legionella pneumophila at a biological treatment plant. (2008) (69)
- Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: communication from the SSC of the ISTH (2017) (64)
- Effects of a 7-day military training exercise on inflammatory biomarkers, serum hepcidin, and iron status (2013) (57)
- Physiological Analysis of the Expression of the Styrene Degradation Gene Cluster in Pseudomonas fluorescensST (2000) (52)
- Real-time PCR and NASBA for rapid and sensitive detection of Vibrio cholerae in ballast water. (2012) (50)
- Alternative routes for dissemination of Legionella pneumophila causing three outbreaks in Norway. (2010) (46)
- Temporal Variability of the Bioaerosol Background at a Subway Station: Concentration Level, Size Distribution, and Diversity of Airborne Bacteria (2013) (45)
- Performing and interpreting individual pharmacokinetic profiles in patients with Hemophilia A or B: Rationale and general considerations (2018) (41)
- Pm promoter expression mutants and their use in broad-host-range RK2 plasmid vectors. (2000) (40)
- Complete genome sequence of the Lactococcus lactis temperate phage phiLC3: comparative analysis of phiLC3 and its relatives in lactococci and streptococci. (2004) (39)
- Use of Real-Time Quantitative PCR for the Analysis of φLC3 Prophage Stability in Lactococci (2003) (37)
- Effects of Diverse Environmental Conditions on φLC3 Prophage Stability in Lactococcus lactis (2005) (36)
- High‐level gene expression in Lactobacillus plantarum using a pheromone‐regulated bacteriocin promoter (2004) (36)
- Determination of normal concentration levels of Cd, Pb, Hg, Cu, Zn and Se in urine of the population in the Czech Republic. (2002) (36)
- Rapid Identification of Bacillus anthracis Spores in Suspicious Powder Samples by Using Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) (2013) (34)
- European principles of inhibitor management in patients with haemophilia (2018) (31)
- Genetic distribution of 295 Bacillus cereus group members based on adk-screening in combination with MLST (Multilocus Sequence Typing) used for validating a primer targeting a chromosomal locus in B. anthracis. (2007) (27)
- Identification of airborne bacteria by 16S rDNA sequencing, MALDI-TOF MS and the MIDI microbial identification system (2015) (26)
- Genotyping of B. licheniformis based on a novel multi-locus sequence typing (MLST) scheme (2012) (26)
- The Czech National Diamond-Blackfan Anemia Registry: clinical data and ribosomal protein mutations update. (2012) (25)
- A multiplatform real-time polymerase chain reaction detection assay for Vibrio cholerae. (2009) (25)
- Airborne Legionella bacteria from pulp waste treatment plant: aerosol particles characterized as aggregates and their potential hazard (2011) (25)
- Detection of bioterror agents in air samples using real‐time PCR (2008) (23)
- Evaluation of a highly discriminating multiplex multi-locus variable-number of tandem-repeats (MLVA) analysis for Vibrio cholerae. (2009) (23)
- Thrombotic events in neonates receiving recombinant factor VIIa or fresh frozen plasma (2009) (23)
- Analysis of the genetic distribution among members of Clostridium botulinum group I using a novel multilocus sequence typing (MLST) assay. (2014) (22)
- The phenotypes of temperature-sensitive mini-RK2 replicons carrying mutations in the replication control gene trfA are suppressed nonspecifically by intragenic cop mutations (1992) (21)
- Analysis of a regulator involved in the genetic switch between lysis and lysogeny of the temperate Lactococcus lactis phage φLC3 (2001) (19)
- L-alanine-induced germination in Bacillus licheniformis -the impact of native gerA sequences (2014) (18)
- Fibrinogen Nový Jičín and Praha II: Cases of hereditary Aα 16 Arg→Cys and Aα 16 Arg→His dysfibrinogenemia (2007) (18)
- Dispersion of Legionella-containing aerosols from a biological treatment plant, Norway. (2011) (18)
- Species-Dependent Phenotypes of Replication-Temperature-SensitivetrfA Mutants of Plasmid RK2: a Codon-Neutral Base Substitution Stimulates Temperature Sensitivity by Leading to Reduced Levels of trfA Expression (1998) (16)
- The prospective Hemophilia Inhibitor PUP Study reveals distinct antibody signatures prior to FVIII inhibitor development. (2020) (16)
- Negative screening tests in classical galactosaemia caused by S135L homozygosity (2009) (16)
- Fibrinogen Nový Jicín and Praha II: cases of hereditary Aalpha 16 Arg-->Cys and Aalpha 16 Arg-->His dysfibrinogenemia. (2007) (16)
- Legionella and non-Legionella bacteria in a biological treatment plant. (2013) (16)
- Significance and causes of abnormal preoperative coagulation test results in children (2012) (16)
- Use of Recombinant Activated Factor VII for Bleeding in Pancreatitis: A Case Series (2005) (15)
- Changes in haemocoagulation in healthy volunteers after a 1-hour thrombotripsy using a diagnostic 2–4 MHz transcranial probe (2008) (15)
- Prophylaxis with recombinant factor VIIa for the management of bleeding episodes during immune tolerance treatment in a boy with severe haemophilia A and high‐response inhibitors (2008) (14)
- On the optimization of performance of time-sharing systems by simulation (1972) (13)
- A case of anaplastic large cell lymphoma‐induced hemophagocytic lymphohistiocytosis in an adolescent female (2007) (13)
- Heterologous gene expression in Lactococcus lactis; expression of the Azotobacter vinelandii algE6 gene product displaying mannuronan C-5 epimerase activity. (2003) (13)
- Transcriptional analysis of the genetic elements involved in the lysogeny/lysis switch in the temperate lactococcal bacteriophage ϕLC3, and identification of the Cro-like protein ORF76 (2003) (12)
- A small derivative of the broad-host-range plasmid RK2 which can be switched from a replicating to a non-replicating state as a response to an externally added inducer. (1999) (12)
- Do the SIPPET study results apply to the patients I treat? (2017) (12)
- The EPIC Study: A Clinical Trial To Assess Whether Early Low Dose Prophylaxis In The Absence Of Immunological Danger Signals Reduces Inhibitor Incidence In Previously Untreated Patients (PUPs) With Hemophilia A (2013) (11)
- Gamma/delta T-cell lymphoma in a dog. (2009) (10)
- Additional evidence of genetic changes in children with ALL and TEL/AML1 fusion gene (2002) (10)
- The life cycles of the temperate lactococcal bacteriophage phiLC3 monitored by a quantitative PCR method. (2000) (10)
- SUCCESSFUL TREATMENT OF ASPERGILLUS BRAIN ABSCESS IN A CHILD WITH ACUTE LYMPHOBLASTIC LEUKEMIA AND LIVER FAILURE (2005) (9)
- Social support and resilience in persons with severe haemophilia: An interpretative phenomenological analysis (2020) (9)
- ST Pseudomonas fluorescens the Styrene Degradation Gene Cluster in Physiological Analysis of the Expression of (2000) (9)
- Safety and efficacy of recombinant activated factor VII in nonhemophilia children with severe or life-threatening bleeding: a report from the SeveNBleeP registry (2014) (8)
- Treatment of deep vein thrombosis with continuous intravenous infusion of LMWH in children--an alternative to subcutaneous application when needed. (2009) (8)
- A Practical, One-Clinic Visit Protocol for Pharmacokinetic Profile Generation with the ADVATE myPKFiT Dosing Tool in Severe Hemophilia A Subjects (2021) (7)
- Czech and Slovak Diamond-Blackfan Anemia (DBA) Registry update: Clinical data and novel causative genetic lesions. (2019) (7)
- Haemophilia care in Central and Eastern Europe: challenges and ways forward from clinicians' perspective (2015) (7)
- RT level test scheduling (1993) (7)
- Can mutations in the ribosomal protein S26 (RPS26) gene lead to Klippel-Feil syndrome in Diamond-Blackfan anemia patients? An update from the Czech Diamond-Blackfan Anemia registry. (2011) (7)
- Inhibitors incidence rate in Czech previously untreated patients with haemophilia A has not increased since introduction of recombinant factor VIII treatment in 2003 (2015) (6)
- Paroxysmal nocturnal hemoglobinuria in a girl with hemolysis and “hematuria” (2004) (5)
- Extraosseal Ewing sarcoma as a rare cause of the blueberry muffin baby syndrome: a case report and the review of the literature. (2011) (5)
- European principles of inhibitor management in patients with haemophilia: implications of new treatment options (2020) (5)
- Analysis of von Willebrand Disease in the South Moravian Population (Czech Republic): Results from the BRNO-VWD Study (2019) (5)
- Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children (2011) (5)
- Sharing datasets of the COVID-19 epidemic in the Czech Republic (2022) (5)
- The use of recombinant–activated factor VII in von Willebrand disease: a case series (2006) (4)
- The second Team Haemophilia Education Meeting, 2016, Frankfurt, Germany (2017) (4)
- Prophylaxis in children with haemophilia in an evolving treatment landscape (2021) (4)
- Novel homozygous fibrinogen Aα chain truncation causes severe afibrinogenemia with life threatening complications in a two-year-old boy. (2013) (3)
- Incidence of inhibitor development in PUPs with severe Haemophilia A in the CEE region between 2005 and 2015. (2020) (3)
- [Recombinant activated factor VII in the treatment of life threatening post-partum haemorrhage; registry UniSeven in the Czech Republic]. (2010) (3)
- Severe postpartum haemorrhage treated with recombinant activated factor VII in 80 Czech patients: analysis of the UniSeven registry. (2011) (3)
- Cerebrovascular Complications of COVID-19 Disease in Children: A Single-Center Case Series (2022) (3)
- Defect in B Cell Production Driven By GATA2 Mutation Results in Their Absolute Reduction and Mature Phenotype in Pediatric Patients (2014) (3)
- Sampling and identification of Legionella spp. at Borregaard Ind. Ltd. (2007) (3)
- Data Coming out of the Human Inhibitor PUP Study (HIPS) Reveal 4 Subgroups of Patients with Distinct Antibody Signatures (2018) (3)
- Changes Identified by Flow Cytometry and WT1 Expression in Consecutive Bone Marrow Samples in Refractory Cytopenia of Childhood and Aplastic Anemia Before Start of the Therapy (2011) (3)
- Validation of the air collector SASS 2000PLUS in a bioaerosol test (BAT) chamber at TNO (2008) (2)
- Fibrinolytic activity in hepatic cirrhosis. (1972) (2)
- [Hemorrhagic complications during warfarin treatment]. (2006) (2)
- Partnering to change the world for people with haemophilia: 6th Haemophilia Global Summit, Prague, Czech Republic, 24–26th September 2015 (2016) (2)
- [Acute lipid degeneration of liver in gravidity (author's transl)]. (1976) (1)
- Early and reliable detection and identification - an important element for efficient biodefense preparedness and response (2005) (1)
- Erratum: A new gene required for cellulose production and a gene encoding cellulolytic activity in Acetobacter xylinum are colocalized with the bcs operon (Journal of Bacteriology 176:3 (665-672)) (1994) (1)
- Detection of Legionella pneumophila in a biological treatment plant by co-cultivatiobn with Acanthamoeba castellanii (2014) (1)
- Detecting and Responding to Bioterrorism (2007) (1)
- Current Guidelines and Strategies in Management of Renal Vein Thrombosis (2013) (1)
- L-alanine-induced germination in Bacillus licheniformis -the impact of native gerA sequences (2014) (1)
- Immune Tolerance Induction Programs (2011) (1)
- Changes in fibrinolytic system after continual Doppler monitoring in healthy volunteers (2009) (1)
- Consensual guidelines of the Czech National Haemophilia Programme (CNHP) for the dia gnosis and treatment of patients with haemophilia, 3rd edition, year 2021 (2021) (1)
- Complete Genome Sequences of Six Legionella pneumophila Isolates from Two Collocated Outbreaks of Legionnaires’ Disease in 2005 and 2008 in Sarpsborg/Fredrikstad, Norway (2016) (1)
- Consensual guidelines of the Czech National Haemophilia Programme (CNHP) for the diagnosis and treatment of patients with congenital haemophilia and FVIII/ FIX inhibitors (2021) (1)
- A Practical, One Clinic Visit, Population Pharmacokinetic (PK) Protocol for Generation of PK Profiles in Subjects with Severe Hemophilia a (2018) (1)
- [Congenital deficiency of Hageman factor (factor XII)]. (1979) (1)
- Composition of Cellular Subsets by Flow Cytometry Identifies Differences Between MDS Subtypes and Aplastic Anemia but No Differences Are Identified Between Cases with and without Monosomy 7. (2009) (1)
- Essential thrombocythaemia in children in the Czech Republic (2006) (1)
- Combined Use of Rapid Von Willebrand Factor (VWF) Activity,VWF-Propetide and Classical VWF Assays for Improved Diagnosisof Von Willebrand Disease Type 1, 2N and 2E Due to Mutations inthe D1, D2, D’, D3 and D4 Domains of the VWF Gene (2019) (1)
- Control Centre for Intensive Care as a Tool for Effective Coordination, Real-Time Monitoring, and Strategic Planning During the COVID-19 Pandemic (2021) (1)
- Hemorrhagic disease of the newborn caused by vitamin K deficiency (2022) (0)
- Scientific Programme (1971) (0)
- The Hardware Accelerator SFDL/SCL (1995) (0)
- Prophylaxis with recombinant factor Viia the management ofbleeding episodes during immune tolerance treatment in a boywith severe haemophilia A and inhibitors (2008) (0)
- [Peripartal life-threatening hemorrhage - interdisciplinary consensus opinion]. (2012) (0)
- Uniseven Registry - Important in Clinical Practise (2008) (0)
- Analysis of von Willebrand Disease in the “Heart of Europe” (2022) (0)
- [Prevention of venous thromboembolism in paediatry]. (2006) (0)
- Inherited coagulation disorders (2022) (0)
- Sharing Datasets of the COVID-19 Pandemic in the Czech Republic (Preprint) (2021) (0)
- [Factor VIII-like antigen in haemophilia A and in Willebrand's disease (author's transl)]. (1975) (0)
- The survival and stability of water pathogens in artificially contaminated water (2009) (0)
- [Current possibilities in the laboratory detection of hemophilia A carrier state]. (1978) (0)
- The SFDL/SCL simulation system (1987) (0)
- Case forum: Capillary leak syndrome—An unusual complication of MDS-RAEB? (2006) (0)
- Acute leukemia in a dog: a case report. (2009) (0)
- Disseminated intravascular coagulation in children (2022) (0)
- Preparation of biological contaminated samples for chemical analysis (2009) (0)
- DETECTING AND RESPONDING (2007) (0)
- IS IT POSSIBLE TO TREAT SAFELY AND EFFECTIVELY DEEP VEIN THROMBOSIS WITH CONTINUOUS I.V. INFUSION OF LMWH IN CHILDREN (2007) (0)
- ADMINISTRATION OF RECOMBINANT ACTIVATED FACTOR VII IN PATIENTS WITHOUT HEMOPHILIA IN THE CZECH REPUBLIC: ANALYSIS OF SELECTED DATA FROM UNISEVEN REGISTER.: 171-S (2005) (0)
- Author's response to reviews Title: Effects of a 7-day military training exercise on inflammatory biomarkers, serum hepcidin, and iron status Authors: (2013) (0)
- Control Centre for Intensive Care as a Tool for Effective Coordination, Real-Time Monitoring, and Strategic Planning During the COVID-19 Pandemic (Preprint) (2021) (0)
- Identification of biological threat agents in the environment and its challenge (2008) (0)
- A Case of Anaplastic Large Cell Lymphoma-Induced HemophagocyticLymphohistiocytosis in an Adolescent Female. A Letter to theEditor. (2007) (0)
- Report from Round Robin 2006 - SIBA 7th laboratory exercise (2007) (0)
- Basic Insights into the Molecular Etiology and Pathology of Von Willebrand Factor (VWF) Behind the ISTH And ECLM Classifications of Von Willebrand Disease Using a Complete Set of VWF Parameters (2019) (0)
- Considerations for shared decision management in previously untreated patients with hemophilia A or B (2023) (0)
- SeveN BleeP Registry – 5 Years Later: An Update. (2010) (0)
- Treatment of Deep Vein Thrombosis with Continuous I.V. Infusion of LMWH in Children - Safe and Efficient Alternative to S.C. Application. (2006) (0)
- Use of Real-Time Quantitative PCR for the Analysis of (cid:2) LC3 Prophage Stability in Lactococci (2002) (0)
- Tracking Legionella in air generated from a biological treatment plant: a case study of the outbreak of legionellosis in Norway (2011) (0)
- Patients with inhibitors: diagnostic and therapeutic challenges, multidisciplinary approach (2016) (0)
- Assessment of Immature Platelet Fraction in Patients with Ph-Negative Myeloproliferative Disorders and Thrombocytosis. (2009) (0)
- [Degradation products of fibrinogen during thrombolysis]. (1973) (0)
- Rapid Identification of Bacillus anthracis Spores in Suspicious Powder Samples by Using Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) (2013) (0)
- Platelet function analyser in diagnosis of von Willebrand disease (2019) (0)
- [Complications in the thrombolytic treatment using streptokinase]. (1974) (0)
- [Quantitative determination of blood factor VIII - like antigen (author's transl)]. (1975) (0)
- [Peripartal life-threating haemorrhage - intensive care and haematological treatment]. (2013) (0)
- Counter biological and chemical terrorism - WP6000: emergency preparedness and response (2009) (0)
- Severe Spontaneous Intracranial Bleeding in 11 Months Old Boy with Congenital Afibrinogenemia with Novel Mutation - Deletion aα 6477A in Fibrinogen Gene (2014) (0)
- Robustness and Generalization of Multilayer Neural Networks (1993) (0)
- Diversity of Airborne Bacteria Concentration Level , Size Distribution , and Background at a Subway Station : Temporal Variability of the Bioaerosol (2013) (0)
- Inherited Pro-Thrombotic Risk Factors in Children of South Moravia Region, Czech Republic (2012) (0)
- Cerebral venous thromboses in children with acute lymphoblastic leukemia – a multicentre study from the Czech Pediatric Hematology Working Group (2018) (0)
- [Antithrombin activity in arteriosclerotic changes of the blood vessels and venous obstruction]. (1971) (0)
- Postauthorization safety surveillance study of antihaemophilic factor (recombinant) reconstituted in 2 mL sterile water for injection in children with haemophilia A (2020) (0)
- Genotyping of B. licheniformisbased on a novel multi-locus sequence typing (MLST) scheme (2012) (0)
- Superiority of the Rapid Von Willebrand Factor (VWF) VWF:GPIbR and VWF:GPIbM Assays in Type 2A, 2B and 2M Von Willebrand Disease (2019) (0)
- [Quantitative assay of fibrinogen and fibrin grafts. Simple radial immunodiffusion and electroimmunoassay (author's transl)]. (1976) (0)
- Biological aerosol background characterization (2011) (0)
- Prospective hemophilia inhibitor PUP study reveals distinct antibody signatures during FVIII inhibitor eradication. (2022) (0)
- Capnometry during neonatal transport—Mini review (2023) (0)
- “UniSeven” - Registry for Life Threatening Bleeding Treated with rFVIIa. Medical and Technical Background and First Output. (2004) (0)
- FP19-TU-01 Sono-thrombolytic activation of the fibrinolytic system in acute stroke patients using a diagnostic 1–4MHz transcranial probe (2009) (0)
- Diethyl ether sorption on titanium trichloride and its correlation with catalytic activity in the polymerization of propene (1983) (0)
- Determination of Two Rapid Von Willebrand Factor (VWF) Activity assays VWF: Gpibm and VWF: Gpibr in Well Defined Von Willebrand Disease Patients Using a Complete Set of Classical and Sensitive VWF Assays (2018) (0)
- The Risk of Thrombotic Events in Neonates Treated with Recombinant Factor VIIa. (2007) (0)
- Prospective Evaluation of Bleeding Incidence in Fibrinogen Deficiency (PRO-RBDD Study) (2016) (0)
- Molecular Etiology and Laboratory Phenotypes of Recessive Von Willebrand Disease 2N Due to Mutations in the D’D3 Factor VIII-Binding Domain of the Von Willebrand Factor Gene: A Critical Appraisal of the Literature and Personal Experiences (2019) (0)
- Heparin-induced thrombocytopenia in children threated with low-molecular weight heparins. Is there any reason to misgiving? (2018) (0)
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