Mahlon DeLong
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American neurologist
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Why Is Mahlon DeLong Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mahlon R. DeLong is an American neurologist and professor at the Medical School of Emory University. His research has advanced the understanding and treatment of Parkinson's disease, dystonia, tremor and other neurological movement disorders.
Mahlon DeLong's Published Works
Published Works
- Parallel organization of functionally segregated circuits linking basal ganglia and cortex. (1986) (8159)
- Primate models of movement disorders of basal ganglia origin (1990) (3600)
- Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. (1990) (2702)
- Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. (1990) (1883)
- Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis (1981) (1721)
- Phenomenology and classification of dystonia: A consensus update (2013) (1573)
- The primate subthalamic nucleus. II. Neuronal activity in the MPTP model of parkinsonism. (1994) (1336)
- Mood Disorders in the Medically Ill: Scientific Review and Recommendations (2005) (1009)
- Circuits and circuit disorders of the basal ganglia. (2007) (1009)
- Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease (2010) (885)
- Deep brain stimulation for Parkinson disease: an expert consensus and review of key issues. (2011) (814)
- Functional and pathophysiological models of the basal ganglia (1996) (734)
- Activity of pallidal neurons during movement. (1971) (713)
- Primate globus pallidus and subthalamic nucleus: functional organization. (1985) (591)
- Treatment of advanced Parkinson's disease by posterior GPi pallidotomy: 1‐year results of a pilot study (1996) (580)
- Neuronal activity in the basal ganglia in patients with generalized dystonia and hemiballismus (1999) (512)
- Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy (2017) (502)
- The subthalamic nucleus in Parkinson's disease: somatotopic organization and physiological characteristics. (2001) (467)
- Altered Tonic Activity of Neurons in the Globus Pallidus and Subthalamic Nucleus in the Primate MPTP Model of Parkinsonism (1987) (444)
- The primate subthalamic nucleus. III. Changes in motor behavior and neuronal activity in the internal pallidum induced by subthalamic inactivation in the MPTP model of parkinsonism. (1994) (402)
- The primate subthalamic nucleus. I. Functional properties in intact animals. (1994) (368)
- Microstimulation of the primate neostriatum. II. Somatotopic organization of striatal microexcitable zones and their relation to neuronal response properties. (1985) (366)
- Relations between parameters of step-tracking movements and single cell discharge in the globus pallidus and subthalamic nucleus of the behaving monkey (1983) (361)
- Prevalence, etiology, and treatment of depression in Parkinson’s disease (2003) (355)
- Prevalence of vitamin d insufficiency in patients with Parkinson disease and Alzheimer disease. (2008) (345)
- Deep Brain Stimulation for Neurologic and Neuropsychiatric Disorders (2006) (314)
- Microelectrode-guided pallidotomy: technical approach and its application in medically intractable Parkinson's disease. (1998) (303)
- Comparison of MPTP-induced changes in spontaneous neuronal discharge in the internal pallidal segment and in the substantia nigra pars reticulata in primates (1999) (302)
- Comorbidity of depression with other medical diseases in the elderly (2002) (276)
- Dopaminergic Neurons Intrinsic to the Primate Striatum (1997) (262)
- Pathophysiology of Parkinson's Disease: The MPTP Primate Model of the Human Disorder (2003) (254)
- Relations between movement and single cell discharge in the substantia nigra of the behaving monkey (1983) (238)
- Randomized trial of pallidotomy versus medical therapy for Parkinson's disease (2003) (222)
- Magnetic resonance imaging-based stereotactic localization of the globus pallidus and subthalamic nucleus. (1999) (218)
- Parkinson's Disease Therapeutics: New Developments and Challenges Since the Introduction of Levodopa (2012) (216)
- Dorsal subthalamotomy for Parkinson's disease (2001) (211)
- Update on models of basal ganglia function and dysfunction. (2009) (210)
- Cognitive impairments in advanced PD without dementia (2002) (202)
- Motor subcircuits mediating the control of movement velocity: a PET study. (1998) (201)
- Bilateral subthalamotomy in Parkinson's disease: initial and long-term response. (2005) (195)
- Milestones in research on the pathophysiology of Parkinson's disease (2011) (192)
- Patient selection and assessment recommendations for deep brain stimulation in Tourette syndrome (2006) (192)
- Excitotoxic acid lesions of the primate subthalamic nucleus result in transient dyskinesias of the contralateral limbs. (1992) (183)
- Scientific and ethical issues related to deep brain stimulation for disorders of mood, behavior, and thought. (2009) (176)
- The focal dystonias: Current views and challenges for future research (2013) (176)
- Thalamic single neuron activity in patients with dystonia: dystonia-related activity and somatic sensory reorganization. (1999) (175)
- Do cortical and basal ganglionic motor areas use “motor programs” to control movement? (1992) (173)
- Functional organization of the basal ganglia: contributions of single-cell recording studies. (1984) (168)
- Activity of basal ganglia neurons during movement. (1972) (168)
- Functional neuroanatomy of the basal ganglia in Parkinson's disease. (2003) (167)
- The Subthalamic Nucleus and Tremor in Parkinson's Disease (2008) (167)
- Role of basal ganglia in limb movements. (1984) (167)
- Single cell studies of the primate putamen (2004) (166)
- Physiologic properties and somatotopic organization of the primate motor thalamus. (1994) (163)
- Corticostriatal Activity in Primary Motor Cortex of the Macaque (2000) (162)
- Basal Ganglia Circuits as Targets for Neuromodulation in Parkinson Disease. (2015) (162)
- A reappraisal of the functions of the nucleus basalis of Meynert (1988) (157)
- Pallidotomy in Parkinson's disease increases supplementary motor area and prefrontal activation during performance of volitional movements an H2(15)O PET study. (1997) (154)
- Single cell studies of the primate putamen (2004) (149)
- Relation of basal ganglia, cerebellum, and motor cortex units to ramp and ballistic limb movements. (1974) (147)
- Microstimulation of the primate neostriatum. I. Physiological properties of striatal microexcitable zones. (1985) (145)
- GPi pallidotomy for dystonia: clinical outcome and neuronal activity. (1998) (143)
- Pathophysiology of parkinsonian motor abnormalities. (1993) (142)
- Activity of identified wrist-related pallidal neurons during step and ramp wrist movements in the monkey. (1990) (139)
- Pathophysiologic basis of surgery for Parkinson's disease. (2000) (137)
- Therapeutic efficacy of unilateral subthalamotomy in Parkinson’s disease: results in 89 patients followed for up to 36 months (2009) (132)
- Effects of Transient Focal Inactivation of the Basal Ganglia in Parkinsonian Primates (2002) (131)
- The functional anatomy of parkinsonian bradykinesia (2003) (131)
- Excitotoxic acid lesions of the primate subthalamic nucleus result in reduced pallidal neuronal activity during active holding. (1992) (130)
- Restoration of thalamocortical activity after posteroventral pallidotomy in Parkinson's disease (1994) (129)
- Beneficial effects of testosterone replacement for the nonmotor symptoms of Parkinson disease. (2002) (129)
- Cortico-basal ganglia relations and coding of motor performance (1983) (127)
- High prevalence of hypovitaminosis D status in patients with early Parkinson disease. (2011) (125)
- Models of basal ganglia function and pathophysiology of movement disorders. (1998) (125)
- Putamen: Activity of Single Units during Slow and Rapid Arm Movements (1973) (124)
- Nucleus basalis of Meynert neuronal activity during a delayed response task in monkey (1986) (122)
- Tactile spatial acuity and roughness discrimination: Impairments due to aging and Parkinson's disease (1997) (121)
- Acute stimulation in the external segment of the globus pallidus improves parkinsonian motor signs (2004) (117)
- Refractory nonmotor symptoms in male patients with Parkinson disease due to testosterone deficiency: a common unrecognized comorbidity. (2002) (115)
- Treatment of advanced Parkinson's disease by unilateral posterior GPi pallidotomy: 4‐year results of a pilot study (2000) (113)
- Deep Brain Stimulation for Movement Disorders of Basal Ganglia Origin: Restoring Function or Functionality? (2016) (111)
- Fiber pathways of basal forebrain cholinergic neurons in monkeys (1987) (107)
- Parkinsonian Symptomatology An Anatomical and Physiological Analysisa a (1988) (106)
- Changing Views of Basal Ganglia Circuits and Circuit Disorders (2010) (103)
- Complications of gamma knife surgery for Parkinson disease. (2001) (103)
- Normalizing motor-related brain activity (2006) (102)
- Electrophysiological studies of the functions of the nucleus basalis in primates. (1991) (99)
- Inversion of Dopamine Responses in Striatal Medium Spiny Neurons and Involuntary Movements (2008) (99)
- Consensus Paper: Experimental Neurostimulation of the Cerebellum (2019) (99)
- The primate globus pallidus: neuronal activity related to direction of movement (2004) (97)
- Synaptic innervation of neurons in the internal pallidal segment by the subthalamic nucleus and the external pallidum in monkeys (1994) (95)
- Context-dependent responses of primate nucleus basalis neurons in a go/no-go task (1990) (95)
- An open study of repetitive transcranial magnetic stimulation in treatment-resistant depression with Parkinson’s disease (2007) (95)
- Antiparkinsonian and Behavioral Effects of Inactivation of the Substantia Nigra Pars Reticulata in Hemiparkinsonian Primates (2001) (92)
- Microstimulation of primate motor thalamus: somatotopic organization and differential distribution of evoked motor responses among subnuclei. (1996) (87)
- Surgery for Parkinson's disease. (1997) (83)
- Alzheimer's Disease and Down's Syndrome * (1982) (79)
- Rodent models for dystonia research: Characteristics, evaluation, and utility (2005) (75)
- Deep-Brain Stimulation for Basal Ganglia Disorders. (2011) (74)
- Parkinsonian symptomatology. An anatomical and physiological analysis. (1988) (73)
- Plasma testosterone levels in Alzheimer and Parkinson diseases (2004) (71)
- Topographic, non-collateralized basal forebrain projections to amygdala, hippocampus, and anterior cingulate cortex in the rhesus monkey (1988) (71)
- Posteroventral pallidotomy for Parkinson's disease. (1992) (70)
- Aberrant phosphorylation of neurofilaments accompanies transmitter-related changes in rat septal neurons following transection of the fimbria-fornix (1989) (70)
- Role of the cerebellum and basal ganglia in voluntary movement (2017) (67)
- Basal ganglia discharge abnormalities in Parkinson's disease. (2006) (66)
- Pseudobulbar crying induced by stimulation in the region of the subthalamic nucleus (2004) (64)
- The contribution of basal ganglia to limb control. (1986) (63)
- Validity of the 30‐item geriatric depression scale in patients with Parkinson's disease (2006) (62)
- Microelectrode-guided pallidotomy for medically intractable Parkinson's disease. (1997) (61)
- Basal forebrain neurons provide major cholinergic innervation of primate neocortex (1986) (60)
- Anatomy and physiology of the basal ganglia: relevance to Parkinson's disease and related disorders. (2007) (59)
- Noncollateral projections of basal forebrain neurons to frontal and parietal neocortex in primates (1985) (59)
- Neurobiology: Oscillations in the basal ganglia (1999) (58)
- Human striatal recordings reveal abnormal discharge of projection neurons in Parkinson’s disease (2016) (56)
- Visual fields in patients with posterior GPi pallidotomy (1998) (55)
- Course of motor and associative pallidothalamic projections in monkeys (2001) (53)
- Primary motor cortex of the parkinsonian monkey: altered encoding of active movement. (2016) (52)
- Effects of deep brain stimulation on rest tremor progression in early stage Parkinson disease (2018) (49)
- Basal ganglia, movement disorders and deep brain stimulation: advances made through non-human primate research (2018) (48)
- Role of the thalamus in parkinsonian tremor: evidence from studies in patients and primate models. (1993) (46)
- Deep brain stimulation for movement and other neurologic disorders (2012) (45)
- Somatotopic organization in the internal segment of the globus pallidus in Parkinson's disease (2010) (44)
- The Basal Ganglia VI (2003) (41)
- Stereotactic pallidotomy in the treatment of Parkinson disease: an expert opinion. (1999) (41)
- Intraoperative neurophysiology in DBS for dystonia (2011) (40)
- Transient impairment of recognition memory following ibotenic-acid lesions of the basal forebrain in macaques (2004) (40)
- Amelioration of sensory limb discomfort of restless legs syndrome by pallidotomy (1999) (40)
- Neuropsychological and psychiatric sequelae of pallidotomy for PD: Clinical trial findings (2002) (39)
- Cognitive and neuropsychiatric effects of subthalamotomy for Parkinson's disease. (2010) (38)
- A personal computer-based spike detector and sorter: implementation and evaluation (1992) (37)
- Functional Implications of Tonic and Phasic Activity Changes in Nucleus Basalis Neurons (1991) (37)
- Effects of scopolamine and physostigmine on recognition memory in monkeys with ibotenic-acid lesions of the nucleus basalis of Meynert (2004) (36)
- The neurophysiologic basis of abnormal movements in basal ganglia disorders. (1983) (36)
- Globus Pallidus lesions in the monkey produced by kainic acid: histologic and behavioral effects. (1979) (35)
- Corticostriatal and mesocortical dopamine systems: do species differences matter? (2013) (34)
- Motor Functions of the Basal Ganglia (2011) (33)
- Discovery of high-frequency deep brain stimulation for treatment of Parkinson disease: 2014 Lasker Award. (2014) (33)
- Wilson's disease. Development of neurological disease after beginning penicillamine therapy. (1990) (32)
- Parkinson's Disease and the Basal Ganglia: Lessons from the Laboratory and from Neurosurgery (1995) (32)
- The External Pallidum and the Subthalamic Nucleus Send Convergent Synaptic Inputs onto Single Neurones in the Internal Pallidal Segment in Monkey:Anatomical Organization and Functional Significance (1994) (30)
- Local Inactivation of the Sensorimotor Territories of the Internal Segment of the Globus Pallidus and the Subthalamic Nucleus Alleviates Parkinsonian Motor Signs in MPTP Treated Monkeys (1994) (29)
- Temporal profile of improvement of tardive dystonia after globus pallidus deep brain stimulation. (2015) (26)
- Animal models for drug discovery in dystonia (2008) (23)
- Testosterone deficiency in a Parkinson's disease clinic: results of a survey. (2004) (23)
- Proceedings of the Second Annual Deep Brain Stimulation Think Tank: What's in the Pipeline (2015) (20)
- Pathophysiological Considerations in Basal Ganglia Surgery: Role of the Basal Ganglia in Hypokinetic and Hyperkinetic Movement Disorders (2000) (19)
- Parkinsonian Tremor is Associated with Low Frequency Neuronal Oscillations in Selective Loops of the Basal Ganglia (1994) (19)
- Tracing the brain's circuitry with functional imaging (1997) (18)
- Time to focus on the locus. (2003) (18)
- Anatomical Investigations of the Pallidotegmental Pathway in Monkey and Man (1996) (18)
- Lesion of the basal ganglia and surgery for Parkinson disease. (2001) (17)
- Globus pallidus deep brain stimulation for adult-onset axial dystonia. (2014) (17)
- Transient manic behavior after pallidotomy (2003) (16)
- Responses of Nucleus Basalis of Meynert Neurons in Behaving Monkeys (1988) (16)
- Deep brain stimulation for Parkinson's disease (2001) (15)
- 25-Hydroxyvitamin D Depletion Does Not Exacerbate MPTP-Induced Dopamine Neuron Damage in Mice (2012) (13)
- Clinical subtypes of anterocollis in parkinsonian syndromes (2012) (13)
- Pallidotomy and Deep Brain Stimulation as a Treatment for Dystonia (1999) (13)
- Possible involvement of central pacemakers in clinical disorders of movement. (1978) (12)
- Clinical outcomes of globus pallidus deep brain stimulation for Parkinson disease: a comparison of intraoperative MRI- and MER-guided lead placement. (2020) (12)
- 1.003 FACILITATING CLINICAL RESEARCH: THE NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS (NINDS) AND STROKE PARKINSON'S DISEASE COMMON DATA ELEMENTS PROJECT (2012) (12)
- Posterior ventral pallidotomy: techniques and theoretical considerations. (1997) (12)
- The primate nucleus basalis of Meynert: neuronal activity related to a visuomotor tracking task (2004) (11)
- Magnetic resonance planned thalamotomy followed by X-ray/CT-guided thalamotomy. (1987) (11)
- Clinical outcomes of pallidal deep brain stimulation for dystonia implanted using intraoperative MRI. (2020) (10)
- Functional Topography of the Human Subthalamic Nucleus: Relevance for Subthalamotomy in Parkinson's Disease (2021) (9)
- Cortical Cholinergic Innervation: Distribution and Source in Monkeys (1986) (9)
- Monkey-based Research on Human Disease: The Implications of Genetic Differences. (2015) (8)
- AUTISM SPECTRUM DISORDERS FOLLOWING IN UTERO EXPOSURE TO ANTIEPILEPTIC DRUGS (2009) (8)
- “Complex” dystonia is not a category in the new 2013 consensus classification (2016) (7)
- Pallidotomy: Theory and Technique (1999) (7)
- [Functional and pathophysiological models of the basal ganglia: therapeutic implications]. (2000) (6)
- Basal Ganglia Circuits in Movement and Movement Disorders (2001) (6)
- Deep-Brain Stimulation for Neurologic and Psychiatric Disorders (2010) (6)
- Deep brain stimulation of the centromedian thalamic nucleus for essential tremor: a case report (2017) (5)
- Ocular Palatal Tremor Plus Dystonia: New Syndromic Association (2015) (5)
- Parkinson Disease and Other Synucleinopathies (2015) (4)
- An 18F-FDG PET study of cervical muscle in parkinsonian anterocollis (2014) (4)
- Levodopa-induced Dyskinesia and Thalamotomy (1993) (4)
- Not our knife: gamma knife surgery for Parkinson disease. (2002) (4)
- Parkinson's Disease (2000) (4)
- Abstracts. Third international dystonia symposium (1997) (3)
- LEVODOPA-INHIBITING EFFECT OF PALLIDAL SURGERY. AUTHORS' REPLY (1997) (3)
- Microphysiological recordings at CT gantry site during stereotactic thalamotomy. (1989) (3)
- Differential responses of nucleus basalis of meynert neurons in a go no go task in monkey macaca mulatta (1986) (3)
- Neurotransmitters and Disorders of the Basal Ganglia (2012) (3)
- The dystonias: Past, present, and future (2013) (3)
- A reappraisal of the fundions of the nudeus basalis of Meynert (1988) (2)
- EAN/MDS-ES Guidelines on pallidotomy for Parkinson´s disease: Let´s be accurate. (2022) (2)
- Systems Level Physiology of the Basal Ganglia, and Pathophysiology of Parkinson's Disease (2008) (2)
- Pathophysiology of Parkinson’s Disease (2009) (2)
- MPTP Parkinsonism Model (2009) (2)
- European Academy of Neurology/Movement Disorder Society-European Section Guidelines on Pallidotomy for Parkinson's Disease: Let's Be Accurate. (2022) (2)
- 122 NEUROCIRCUITRY OF PARKINSON ’ S DISEASE (2002) (2)
- Secondary Dystonia in a Novel Mitochondriopathy Responsive to Deep Brain Stimulation Therapy (2020) (2)
- Lasker Award Winner Mahlon DeLong (2014) (1)
- Erratum: Pallidotomy in Parkinson's disease increases supplementary motor area and prefrontal activation during performance of volitional movements. An H2 15O PET study (Brain. Journal of Neurology (1997) 120, 8 (1301-1313)) (1998) (1)
- [Neuronal activity in the basal ganglia of the behaving monkey: insights into function and pathophysiology of clinical disorders]. (1982) (1)
- Segregating the Frontal Cortex with Deep Brain Stimulation (2023) (1)
- Rationale for Surgical Interventions in Movement Disorders (2011) (1)
- Basal Ganglia, Functional Organization (2010) (1)
- Advanced therapies for movement disorders in neurotherapeutics (2008) (1)
- Naturalizing motor control theory: Isn't it time for a new paradigm? (1992) (1)
- Non-animal Replacements for Acute Toxicity Testing (2015) (1)
- SURGERY FOR PD. AUTHOR'S REPLY (1993) (0)
- Dear Editor. (2015) (0)
- Clustering of pallidal neurons responding to manipulations of single joints in the monkey (1990) (0)
- European Academy of Neurology/Movement Disorder Society-European Section´s Guidelines on pallidotomy for Parkinson´s disease: Let´s remain accurate. (2022) (0)
- P2.048 Screening and selection process for deep brain stimulation: the Emory experience (2009) (0)
- Back 43 The Basal Ganglia (2006) (0)
- Reply (1997) (0)
- Parkinson's disease. (2000) (0)
- Deep Brain Stimulation for Movement Disorders of Basal Ganglia Origin: Restoring Function or Functionality? (2016) (0)
- Invited Commentary (0)
- Reply: Dystonia after severe head injuries (2014) (0)
- Consensus Paper: Experimental Neurostimulation of the Cerebellum (2019) (0)
- Patients with Cognitive Impairment in Parkinson's Disease Benefit from Deep Brain Stimulation: A Case‐Control Study (2023) (0)
- Clinical Outcomes Of Deep Brain Stimulation Placement Using Intraoperative MRI for Parkinson Disease (P3.359) (2016) (0)
- Concerns about the European Academy's Recommendations and Guidelines Regarding Pallidotomy for Parkinson's Disease (2023) (0)
- Gamma knife radiosurgery as an alternative form of therapy for movement disorders. Authors' reply (2002) (0)
- Deep Brain Stimulation Placement Using Intraoperative MRI for Dystonia: One Year Clinical Outcomes (S30.003) (2016) (0)
- Concerns About the European Academy's Recommendations and Guidelines Regarding Pallidotomy for Parkinson's Disease (2023) (0)
- Deep Brain Stimulation for Tremor in Parkinson’s Disease (2019) (0)
- Reply (1997) (0)
- Treatment of Essential Tremor: Deep Brain Stimulation (2019) (0)
- Alim-Louis Benabid and Mahlon DeLong win the 2014 (2014) (0)
- Evidence-Based Reviews and Guidelines: Let's Avoid Future Confusion. (2022) (0)
- Muhammad Ali and Young-Onset Idiopathic Parkinson Disease-The Missing Evidence. (2022) (0)
- Editorial Board (1991) (0)
- Surgery for PD (1993) (0)
- Response : Treating Parkinson's Disease with Lesions of the Subthalamic Nucleus (1991) (0)
- Hemiballismus induced by microlesions of monkey subthalamic nucleus (STN) (1991) (0)
- Title Proceedings of the Second Annual Deep Brain Stimulation Think Tank : What ' s in the Pipeline Permalink (2015) (0)
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