Peter G. Schultz

Q: What Schools Are Affiliated With Peter G. Schultz

Peter G. Schultz is affiliated with the following schools: University of California, Berkeley, Yale University, California Institute of Technology, Princeton University, Stanford University, Nagoya University, Massachusetts Institute of Technology

Peter G. Schultz's AcademicInfluence.com Rankings

Peter G. Schultz

Biology

#769

World Rank

#1328

Historical Rank

#414

USA Rank

Genetics

#169

World Rank

#209

Historical Rank

#97

USA Rank

biology Degrees

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Biology

Peter G. Schultz's Degrees

PhD Chemistry California Institute of Technology
Bachelors Chemistry California Institute of Technology

Why Is Peter G. Schultz Influential?

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According to Wikipedia, Peter G. Schultz is an American chemist. He is the CEO and Professor of Chemistry at The Scripps Research Institute, the founder and former director of GNF, and the founding director of the California Institute for Biomedical Research , established in 2012. In August 2014, Nature Biotechnology ranked Schultz the #1 top translational researcher in 2013.

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Peter G. Schultz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Organization of 'nanocrystal molecules' using DNA (1996) (2306)
Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock (2002) (2233)
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites (2009) (2058)
Large-scale analysis of the human and mouse transcriptomes (2002) (1576)
Adding new chemistries to the genetic code. (2010) (1436)
Expanding the Genetic Code of Escherichia coli (2001) (1269)
A chemical switch for inhibitor-sensitive alleles of any protein kinase (2000) (1035)
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines (2007) (1008)
Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells (2010) (931)
A general method for site-specific incorporation of unnatural amino acids into proteins. (1989) (865)
Genomic analysis of the host response to hepatitis C virus infection (2002) (846)
A Combinatorial Approach to Materials Discovery (1995) (800)
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. (1998) (761)
A Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFAT (2005) (735)
Expanding the genetic code. (2002) (703)
An Expanded Eukaryotic Genetic Code (2003) (696)
Molecular classification of human carcinomas by use of gene expression signatures. (2001) (680)
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974 (2013) (654)
Genomically Recoded Organisms Expand Biological Functions (2013) (649)
Addition of p-azido-L-phenylalanine to the genetic code of Escherichia coli. (2002) (622)
Effects of environmental enrichment on gene expression in the brain. (2000) (607)
Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli (2002) (602)
Mitotic misregulation and human aging. (2000) (586)
An enhanced system for unnatural amino acid mutagenesis in E. coli. (2010) (554)
The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations (2009) (537)
At the crossroads of chemistry and immunology: catalytic antibodies. (1991) (523)
DNA-Based Assembly of Gold Nanocrystals. (1999) (521)
Selective chemical catalysis by an antibody. (1986) (521)
Structural insights into the evolution of an antibody combining site. (1997) (518)
Single-molecule fluorescence spectroscopy of enzyme conformational dynamics and cleavage mechanism. (1999) (472)
Single-pair fluorescence resonance energy transfer on freely diffusing molecules: observation of Förster distance dependence and subpopulations. (1999) (464)
Synthesis of site-specific antibody-drug conjugates using unnatural amino acids (2012) (458)
A Class of Cobalt Oxide Magnetoresistance Materials Discovered with Combinatorial Synthesis (1995) (433)
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen (2008) (423)
Discovery of SARS-CoV-2 Antivirals through Large-scale Drug Repositioning (2020) (422)
Single-molecule protein folding: diffusion fluorescence resonance energy transfer studies of the denaturation of chymotrypsin inhibitor 2. (2000) (404)
A regenerative approach to the treatment of multiple sclerosis (2013) (401)
Identification of Small Molecule Activators of Cryptochrome (2012) (397)
Oxysterols direct immune cell migration via EBI2 (2011) (385)
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline (2002) (372)
A chemical toolkit for proteins — an expanded genetic code (2006) (367)
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4 (2009) (358)
Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK (2007) (348)
A Stem Cell–Based Approach to Cartilage Repair (2012) (335)
Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae. (2003) (334)
Addition of the keto functional group to the genetic code of Escherichia coli (2002) (318)
Synthetic small molecules that control stem cell fate (2003) (314)
The effects of aging on gene expression in the hypothalamus and cortex of mice. (2001) (311)
Self-renewal of embryonic stem cells by a small molecule (2006) (311)
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery (2011) (307)
A role for chemistry in stem cell biology (2004) (303)
Designing meaningful density functional theory calculations in materials science—a primer (2004) (294)
Switch-mediated activation and retargeting of CAR-T cells for B-cell malignancies (2016) (286)
Beyond the Canonical 20 Amino Acids: Expanding the Genetic Lexicon* (2010) (285)
Efficient incorporation of unnatural amino acids into proteins in Escherichia coli (2006) (282)
Dedifferentiation of lineage-committed cells by a small molecule. (2004) (277)
A genetically encoded fluorescent amino acid. (2006) (277)
An expanded genetic code with a functional quadruplet codon. (2004) (274)
Peptide ligands for a sugar-binding protein isolated from a random peptide library. (1992) (273)
General approach to the synthesis of short .alpha.-helical peptides (1991) (270)
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry (2003) (269)
A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3β (2008) (261)
A Novel Copper-Mediated DNA Base Pair (2000) (257)
Site-specific PEGylation of proteins containing unnatural amino acids. (2004) (244)
A genetically encoded photocaged amino acid. (2004) (242)
The in vivo neuromodulatory effects of the herbal medicine ginkgo biloba (2001) (242)
Mechanistic Studies of the Oxidation of Isoniazid by the Catalase Peroxidase from Mycobacterium tuberculosis (1994) (240)
An approach to rapid protein crystallization using nanodroplets (2002) (239)
A general approach to site-specific antibody drug conjugates (2014) (236)
Small molecules that induce cardiomyogenesis in embryonic stem cells. (2004) (231)
Substrate recognition by the AAA+ chaperone ClpB (2004) (229)
Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis (2015) (228)
Generation of a bacterium with a 21 amino acid genetic code. (2003) (226)
An unnatural biopolymer. (1993) (225)
Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors. (1999) (225)
Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. (2008) (220)
A versatile platform for single- and multiple-unnatural amino acid mutagenesis in Escherichia coli. (2013) (220)
Site-specific incorporation of biophysical probes into proteins. (1994) (210)
Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway. (2004) (209)
Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice (2002) (207)
The Immunological Evolution of Catalysis (1996) (207)
High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase (2010) (205)
Genetic incorporation of unnatural amino acids into proteins in mammalian cells (2007) (204)
Protein conjugation with genetically encoded unnatural amino acids. (2013) (202)
Genome-wide gene expression profiles of the developing mouse hippocampus (2001) (202)
Versatile strategy for controlling the specificity and activity of engineered T cells (2016) (201)
Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity (2009) (201)
A Comparison of the Celera and Ensembl Predicted Gene Sets Reveals Little Overlap in Novel Genes (2001) (201)
Sapphire (0001) Surface, Clean and with d -Metal Overlayers (1999) (200)
Site-directed spin labeling of a genetically encoded unnatural amino acid (2009) (200)
A genetically encoded infrared probe. (2006) (198)
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells (2003) (198)
A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells. (2002) (192)
A general approach for the generation of orthogonal tRNAs. (2001) (191)
Studies on the Mechanism of Action of Isoniazid and Ethionamide in the Chemotherapy of Tuberculosis (1995) (188)
Myoseverin, a microtubule-binding molecule with novel cellular effects (2000) (187)
A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase. (2006) (186)
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing (2020) (184)
Optimized clinical performance of growth hormone with an expanded genetic code (2011) (184)
Ratiometric single-molecule studies of freely diffusing biomolecules. (2001) (184)
Control of protein phosphorylation with a genetically encoded photocaged amino acid. (2007) (184)
Structure of a copper-mediated base pair in DNA. (2001) (183)
Playing with the Molecules of Life. (2018) (183)
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (2013) (178)
Electronic structure of intrinsic defects in crystalline germanium telluride (2006) (178)
Probing Protein Structure and Function with an Expanded Genetic Code (1995) (178)
A genomic screen for activators of the antioxidant response element (2007) (177)
A genetically encoded photocaged tyrosine. (2006) (173)
An efficient system for the evolution of aminoacyl-tRNA synthetase specificity (2002) (172)
A small molecule primes embryonic stem cells for differentiation. (2009) (170)
A new strategy for the site-specific modification of proteins in vivo. (2003) (170)
An efficient rapid system for profiling the cellular activities of molecular libraries. (2006) (168)
Adding amino acids to the genetic repertoire. (2005) (168)
An evolved aminoacyl-tRNA synthetase with atypical polysubstrate specificity. (2011) (167)
A genetically encoded fluorescent amino acid. (2006) (167)
In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy. (2008) (166)
Engineering a tRNA and aminoacyl-tRNA synthetase for the site-specific incorporation of unnatural amino acids into proteins in vivo. (1997) (165)
A general and efficient route for chemical aminoacylation of transfer RNAs (1991) (164)
Progress toward the evolution of an organism with an expanded genetic code. (1999) (164)
Site-specific incorporation of novel backbone structures into proteins. (1992) (162)
Oxygen-induced restructuring of the TiO2(110) surface: a comprehensive study (1999) (160)
Reshaping Antibody Diversity (2013) (158)
Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. (2009) (157)
Directed evolution of the site specificity of Cre recombinase (2002) (156)
A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer. (2008) (155)
In vivo incorporation of an alkyne into proteins in Escherichia coli. (2005) (153)
Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic (2020) (152)
Biosynthetic method for introducing unnatural amino acids site-specifically into proteins. (1991) (150)
Ratiometric measurement and identification of single diffusing molecules (1999) (148)
The incorporation of a photoisomerizable amino acid into proteins in E. coli. (2006) (146)
Genetic incorporation of multiple unnatural amino acids into proteins in mammalian cells. (2013) (146)
A New Strategy for the Synthesis of Glycoproteins (2004) (145)
Enthalpy arrays. (2004) (145)
An antibody-catalyzed bimolecular Diels-Alder reaction (1990) (144)
Site-directed mutagenesis with an expanded genetic code. (1995) (144)
Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase. (2000) (143)
A metabolite-derived protein modification integrates glycolysis with KEAP1-NRF2 signaling (2018) (143)
A combinatorial scaffold approach toward kinase-directed heterocycle libraries. (2002) (143)
Site-specific protein modification using a ketone handle (1996) (142)
Immunological origins of binding and catalysis in a Diels-Alderase antibody. (1998) (142)
A genetically encoded fluorescent probe in mammalian cells. (2013) (142)
Identification of p53 regulators by genome-wide functional analysis. (2004) (141)
A functional genomics approach to the mode of action of apratoxin A (2006) (140)
A method for directed evolution and functional cloning of enzymes. (1998) (140)
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation. (2010) (139)
Protein evolution with an expanded genetic code (2008) (139)
A genetically encoded bidentate, metal-binding amino acid. (2007) (138)
Synthesis of bispecific antibodies using genetically encoded unnatural amino acids. (2012) (137)
Profiling protein function with small molecule microarrays (2002) (136)
DNA affinity cleaving : Sequence specific cleavage of DNA by Distamycin-EDTA - Fe(II) and EDTA-distamycin Fe(II) (1984) (135)
Directed evolution of novel polymerase activities: Mutation of a DNA polymerase into an efficient RNA polymerase (2002) (135)
Evolution of amber suppressor tRNAs for efficient bacterial production of proteins containing nonnatural amino acids. (2009) (134)
Genome-wide functional analysis of human cell-cycle regulators (2006) (134)
In Vivo Photocrosslinking with Unnatural Amino Acid Mutagenesis (2002) (133)
Overexpression, Purification, and Characterization of the Catalase-peroxidase KatG from Mycobacterium tuberculosis* (1997) (132)
Chemical control of stem cell fate and developmental potential. (2011) (132)
Expanding the scope of RNA catalysis. (1994) (130)
Expanding the genetic code: selection of efficient suppressors of four-base codons and identification of “shifty” four-base codons with a library approach in Escherichia coli1 (2001) (128)
A new strategy for the generation of catalytic antibodies (1989) (127)
A novel silver(i)-mediated DNA base pair. (2002) (127)
Combinatorial synthesis and high throughput evaluation of ferroelectric/dielectric thin-film libraries for microwave applications (1998) (127)
A facile system for encoding unnatural amino acids in mammalian cells. (2009) (126)
Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter (2001) (126)
Recombinant expression of selectively sulfated proteins in Escherichia coli (2006) (125)
A New Functional Suppressor tRNA/ Aminoacyl-tRNA Synthetase Pair for the in Vivo Incorporation of Unnatural Amino Acids into Proteins (2000) (125)
The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis (2018) (124)
Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation. (2007) (123)
A phage display system with unnatural amino acids. (2004) (123)
Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells (2007) (123)
Generation of a hybrid sequence-specific single-stranded deoxyribonuclease. (1987) (122)
Redirection of genetically engineered CAR-T cells using bifunctional small molecules. (2015) (121)
The site-specific incorporation of p-iodo-L-phenylalanine into proteins for structure determination (2004) (121)
Structural plasticity and the evolution of antibody affinity and specificity. (2003) (121)
CXCR4 Expression in Prostate Cancer Progenitor Cells (2012) (120)
Probing protein stability with unnatural amino acids. (1992) (119)
Development and characterization of nonpeptidic small molecule inhibitors of the XIAP/caspase-3 interaction. (2003) (119)
A small-molecule agonist of the Wnt signaling pathway. (2005) (118)
Monitoring the conformational fluctuations of DNA hairpins using single-pair fluorescence resonance energy transfer. (2001) (117)
Site-specific DNA-antibody conjugates for specific and sensitive immuno-PCR (2012) (117)
An antibody-catalyzed Claisen rearrangement (1988) (116)
Combination Therapy Targeting Both Tumor-Initiating and Differentiated Cell Populations in Prostate Carcinoma (2010) (115)
Analysis of the Heyd-Scuseria-Ernzerhof density functional parameter space. (2012) (113)
Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe. (2009) (111)
Identification of Human Kinases Involved in Hepatitis C Virus Replication by Small Interference RNA Library Screening* (2008) (111)
Site-specific incorporation of a redox-active amino acid into proteins. (2003) (111)
Small-molecule synergist of the Wnt/β-catenin signaling pathway (2007) (111)
Site-specific incorporation of methyl- and acetyl-lysine analogues into recombinant proteins. (2008) (110)
Porphyrin metalation catalyzed by a small RNA molecule (1996) (109)
Enhancing protein stability with extended disulfide bonds (2016) (109)
Evolution of cyclic peptide protease inhibitors (2011) (109)
Development of a functionalized xenon biosensor. (2004) (109)
A genome-wide overexpression screen in yeast for small-molecule target identification. (2005) (109)
The use of 5'-phospho-2 deoxyribocytidylylriboadenosine as a facile route to chemical aminoacylation of tRNA. (1989) (109)
Searching for Interferon-Induced Genes That Inhibit Hepatitis B Virus Replication in Transgenic Mouse Hepatocytes (2003) (108)
CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling (2012) (108)
Construction of a light-activated protein by unnatural amino acid mutagenesis (1991) (107)
Expanding the genetic code. (2002) (107)
A small molecule accelerates neuronal differentiation in the adult rat (2010) (106)
A small molecule promotes mitochondrial fusion in mammalian cells. (2012) (106)
Design synthesis of a sequence-specific DNA cleaving molecule. (Distamycin-EDTA)iron(II) (1982) (106)
A method for the generation of glycoprotein mimetics. (2003) (105)
Probing the structure and mechanism of Ras protein with an expanded genetic code. (1993) (105)
At the Interface of Chemical and Biological Synthesis: An Expanded Genetic Code. (2016) (105)
Ribosomal route to small-molecule diversity. (2012) (104)
Scanning tip microwave near field microscope (1996) (103)
Systematic chromosomal deletion of bacterial ribosomal protein genes. (2011) (102)
A Structure-Based Library Approach to Kinase Inhibitors (1996) (101)
A Strategy for the Chemical Synthesis of Nanostructures (1995) (101)
Genome-scale functional profiling of the mammalian AP-1 signaling pathway (2003) (100)
SDS capillary gel electrophoresis of proteins in microfabricated channels. (1999) (100)
Unnatural amino acid mutagenesis of green fluorescent protein. (2003) (100)
A new strategy for selective protein cleavage (1990) (99)
Nondestructive Imaging of Dielectric-Constant Profiles and Ferroelectric Domains with a Scanning-Tip Microwave Near-Field Microscope (1997) (99)
Adding L-3-(2-Naphthyl)alanine to the genetic code of E. coli. (2002) (98)
Probing Protein–Protein Interactions with a Genetically Encoded Photo‐crosslinking Amino Acid (2011) (97)
Antibody catalysis of difficult chemical transformations (1993) (97)
An experimental approach to evaluating the role of backbone interactions in proteins using unnatural amino acid mutagenesis. (1997) (97)
A genomic screen identifies TYRO3 as a MITF regulator in melanoma (2009) (95)
Nonequivalence of the generalized gradient approximations PBE and PW91 (2006) (95)
Theory of defect levels and the "band gap problem" in silicon. (2006) (94)
Screening the mammalian extracellular proteome for regulators of embryonic human stem cell pluripotency (2010) (94)
Density functional theory and DFT+U study of transition metal porphines adsorbed on Au(111) surfaces and effects of applied electric fields. (2006) (91)
A Genetically Encoded Diazirine Photocrosslinker in Escherichia coli (2007) (91)
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria (2017) (91)
Reversine increases the plasticity of lineage-committed mammalian cells (2007) (91)
A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals (2020) (91)
Progress toward an expanded eukaryotic genetic code. (2003) (91)
A biosynthetic route to dehydroalanine-containing proteins. (2007) (89)
Adaptation of an orthogonal archaeal leucyl-tRNA and synthetase pair for four-base, amber, and opal suppression. (2003) (89)
Incorporation of fluorotyrosines into ribonucleotide reductase using an evolved, polyspecific aminoacyl-tRNA synthetase. (2011) (89)
Site-specific incorporation of ε-N-crotonyllysine into histones. (2012) (89)
A synthetic small molecule that induces neuronal differentiation of adult hippocampal neural progenitor cells. (2006) (89)
Blue-fluorescent antibodies. (2000) (88)
Efforts toward expansion of the genetic alphabet: replication of DNA with three base pairs. (2001) (88)
From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling. (2001) (88)
Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells (2013) (88)
An improved system for the generation and analysis of mutant proteins containing unnatural amino acids in Saccharomyces cerevisiae. (2007) (87)
A Chemical Genomic Analysis of Decoquinate, a Plasmodium falciparum Cytochrome b Inhibitor (2011) (87)
Selective Staudinger Modification of Proteins Containing p‐Azidophenylalanine (2005) (86)
The Solid - Phase Synthesis of Oligoureas (1996) (86)
An expanded genetic code in mammalian cells with a functional quadruplet codon. (2013) (86)
Synthesis and Isolatin of a Homodimer of Cadmium Selenide Nanocrystals (1997) (86)
siRNA in human cells selectively localizes to target RNA sites (2006) (86)
Identification of small-molecule inducers of pancreatic β-cell expansion (2009) (85)
Stereospecific Hydrolysis of Alkyl Esters by Antibodies (1989) (85)
The interplay between chemistry and biology in the design of enzymatic catalysts. (1988) (85)
Exploring the limits of codon and anticodon size. (2002) (85)
Peroxidase activity of an antibody-heme complex (1990) (85)
A genetically encoded metabolically stable analogue of phosphotyrosine in Escherichia coli. (2007) (84)
Two-dimensional IR spectroscopy of protein dynamics using two vibrational labels: a site-specific genetically encoded unnatural amino acid and an active site ligand. (2011) (83)
Local electrostatic moments and periodic boundary conditions (1999) (83)
In vivo selection for metastasis promoting genes in the mouse (2007) (83)
Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody-Drug Conjugates. (2016) (83)
Uncoupling of transfer of the presequence and unfolding of the mature domain in precursor translocation across the mitochondrial outer membrane. (1999) (82)
Site-specific labeling of proteins with NMR-active unnatural amino acids (2010) (82)
The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication. (2006) (81)
Synthesis at the interface of chemistry and biology. (2009) (80)
Site-specific antibody-polymer conjugates for siRNA delivery. (2013) (80)
Small-molecule inducer of β cell proliferation identified by high-throughput screening. (2013) (80)
Cover Picture: Expanding the Genetic Code (Angew. Chem. Int. Ed. 1/2005) (2005) (80)
An expanding genetic code. (2004) (79)
A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis (2017) (79)
A Genetically Encoded aza-Michael Acceptor for Covalent Cross-Linking of Protein–Receptor Complexes (2014) (79)
A method to site-specifically introduce methyllysine into proteins in E. coli. (2010) (78)
An immunosuppressive antibody-drug conjugate. (2015) (78)
Age-related effects of Ginkgo biloba extract on synaptic plasticity and excitability (2004) (78)
An expanding genetic code. (2005) (78)
Biosynthesis of a site-specific DNA cleaving protein. (2008) (77)
Introduction of nucleophiles and spectroscopic probes into antibody combining sites. (1988) (76)
Probing the environment along the protein import pathways in yeast mitochondria by site-specific photocrosslinking. (1997) (76)
Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis. (2005) (76)
All-atom ab initio energy minimization of the kaolinite crystal structure (1997) (75)
Evolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coli (2012) (75)
In vitro suppression of an amber mutation by a chemically aminoacylated transfer RNA prepared by runoff transcription (1990) (74)
A small-molecule inducer of the antioxidant response element. (2010) (74)
Mechanistic studies of a small-molecule modulator of SMN2 splicing (2018) (74)
Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer. (2016) (73)
Roadmap on multiscale materials modeling (2020) (73)
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen (2010) (73)
Expression studies of catalytic antibodies. (1995) (73)
A genetically encoded boronate-containing amino acid. (2008) (72)
Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells (2004) (72)
Design of allele-specific protein methyltransferase inhibitors. (2001) (72)
Identification of the tyrosine phosphatase PTP-MEG2 as an antagonist of hepatic insulin signaling. (2006) (72)
TEMPORAL FLUCTUATIONS OF FLUORESCENCE RESONANCE ENERGY TRANSFER BETWEEN TWO DYES CONJUGATED TO A SINGLE PROTEIN (1999) (72)
Designing small-molecule switches for protein-protein interactions. (2000) (72)
The selective incorporation of alkenes into proteins in Escherichia coli. (2002) (71)
Combinatorial synthesis of 2,9-substituted purines (1997) (71)
Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. (2007) (71)
A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer. (2015) (71)
Tom40 protein import channel binds to non-native proteins and prevents their aggregation (2003) (71)
Bispecific small molecule–antibody conjugate targeting prostate cancer (2013) (71)
Optimization of Xenon Biosensors for Detection of Protein Interactions (2005) (69)
A Small‐Molecule Antagonist of the Hedgehog Signaling Pathway (2007) (69)
The interplay between binding energy and catalysis in the evolution of a catalytic antibody (1997) (69)
Inhibition and reversal of myogenic differentiation by purine-based microtubule assembly inhibitors. (2002) (69)
A second-generation copper(II)-mediated metallo-DNA-base pair. (2004) (67)
COMBINATORIAL SYNTHESIS AND EVALUATION OF EPITAXIAL FERROELECTRIC DEVICE LIBRARIES (1998) (67)
Targeting human C-type lectin-like molecule-1 (CLL1) with a bispecific antibody for immunotherapy of acute myeloid leukemia. (2014) (66)
Three sweet receptor genes are clustered in human Chromosome 1 (2003) (66)
Self-assembled antibody multimers through peptide nucleic acid conjugation. (2013) (66)
Unnatural amino acid mutagenesis of fluorescent proteins. (2012) (66)
A comparative analysis of the immunological evolution of antibody 28B4. (2001) (65)
Somatic hypermutation maintains antibody thermodynamic stability during affinity maturation (2013) (65)
Photosensitized cleavage of a thymine dimer by an antibody (1988) (64)
Development of improved tRNAs for in vitro biosynthesis of proteins containing unnatural amino acids. (1996) (64)
Generation of a catalytic antibody by site-directed mutagenesis. (1989) (63)
Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors (2018) (62)
Alternate protein frameworks for molecular recognition. (1995) (62)
AB INITIO STRUCTURAL PREDICTIONS FOR ULTRATHIN ALUMINUM OXIDE FILMS ON METALLIC SUBSTRATES (1999) (61)
Evolution of proteins with genetically encoded "chemical warheads". (2009) (61)
A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts. (1999) (61)
Probing the mechanism of staphylococcal nuclease with unnatural amino acids: kinetic and structural studies. (1993) (60)
Combinatorial approaches to materials science (1998) (60)
An archaebacteria-derived glutamyl-tRNA synthetase and tRNA pair for unnatural amino acid mutagenesis of proteins in Escherichia coli. (2003) (60)
Crystal structures of apo wild‐type M. jannaschii tyrosyl‐tRNA synthetase (TyrRS) and an engineered TyrRS specific for O‐methyl‐L‐tyrosine (2005) (60)
Genetic Incorporation of Unnatural Amino Acids into Proteins in Mycobacterium tuberculosis (2010) (60)
Protein biosynthesis with conformationally restricted amino acids (1993) (59)
Microfluidic device for single-molecule experiments with enhanced photostability. (2009) (59)
Small molecule antagonists in distinct binding modes inhibit drug-resistant mutant of smoothened. (2011) (59)
Site-specific coupling and sterically controlled formation of multimeric antibody fab fragments with unnatural amino acids. (2011) (59)
Identification of a novel protein regulating microtubule stability through a chemical approach. (2004) (59)
Genetically encoded alkenes in yeast. (2010) (59)
1,1'-carbonylbis(3-methylimidazolium) triflate: an efficient reagent for aminoacylations (1989) (58)
Analysis of Active Site Residues in Escherichia coli Chorismate Mutase by Site-Directed Mutagenesis (1996) (58)
Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis (2017) (57)
Antibody catalysis in reverse micelles (1988) (57)
Mutagenesis Study of Active Site Residues in Chorismate Mutase from Bacillus subtilis (1996) (57)
Exploring the potential impact of an expanded genetic code on protein function (2015) (56)
First-principles approach to the charge-transport characteristics of monolayer molecular-electronics devices : Application to hexanedithiolate devices (2006) (56)
Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin. (2007) (56)
Development of A Chimeric Antigen Receptor Targeting C-Type Lectin-Like Molecule-1 for Human Acute Myeloid Leukemia (2017) (55)
Crystal structures of the free and liganded form of an esterolytic catalytic antibody. (1997) (55)
Site-specific cleavage of duplex DNA by a semisynthetic nuclease via triple-helix formation. (1990) (55)
Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells. (2011) (55)
Genetic Incorporation of Histidine Derivatives Using an Engineered Pyrrolysyl-tRNA Synthetase (2014) (55)
The chemistry of the antibody molecule. (2002) (54)
Discovery of estrogen sulfotransferase inhibitors from a purine library screen. (2001) (54)
A small molecule modulates circadian rhythms through phosphorylation of the period protein. (2011) (54)
Small-molecule synergist of the Wnt/beta-catenin signaling pathway. (2007) (54)
Synchrotron x-ray microbeam diagnostics of combinatorial synthesis (1998) (54)
Layer intermixing during metal/metal oxide adsorption: Ti/sapphire(0001) (2002) (54)
A CXCR4-targeted site-specific antibody-drug conjugate. (2014) (54)
The effect of minor-groove hydrogen-bond acceptors and donors on the stability and replication of four unnatural base pairs. (2003) (53)
Recombinant thiopeptides containing noncanonical amino acids (2016) (53)
Stable and Selective Hybridization of Oligonucleotides with Unnatural Hydrophobic Bases (2000) (53)
A phosphoproteomic analysis of the ErbB2 receptor tyrosine kinase signaling pathways. (2006) (52)
A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers (2017) (52)
A Genetically Encoded ε‐N‐Methyl Lysine in Mammalian Cells (2010) (52)
One-pot two-step microwave-assisted reaction in constructing 4,5-disubstituted pyrazolopyrimidines. (2003) (52)
Small molecules and future regenerative medicine. (2005) (52)
Ab initio calculations of Ru, Pd, and Ag cluster structure with 55, 135, and 140 atoms (1997) (52)
Photocleavage of the polypeptide backbone by 2-nitrophenylalanine. (2009) (52)
Repurposing isoxazoline veterinary drugs for control of vector-borne human diseases (2018) (52)
Mutational Analysis of Backbone Hydrogen Bonds in Staphylococcal Nuclease (1997) (52)
Structural plasticity of an aminoacyl-tRNA synthetase active site. (2006) (52)
Opportunities at the interface of chemistry and biology. (1999) (51)
Theory of persistent, p-type, metallic conduction in c-GeTe (2005) (51)
Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids (2009) (51)
Immunochemical termination of self-tolerance (2008) (51)
Antibody-Catalyzed Prodrug Activation (1994) (51)
Long‐range poisoning of D2 dissociative chemisorption on Pt(111) by coadsorbed K (1991) (51)
Mouse limb skeletal growth and synovial joint development are coordinately enhanced by Kartogenin. (2014) (51)
Deeply Inverted Electron-Hole Recombination in a Luminescent Antibody-Stilbene Complex (2008) (50)
A New Orthogonal Suppressor tRNA/Aminoacyl‐tRNA Synthetase Pair for Evolving an Organism with an Expanded Genetic Code (2000) (50)
Distamycin and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving. (1984) (50)
The synthesis and biological characterization of a ceramide library. (2002) (50)
Selective formation of covalent protein heterodimers with an unnatural amino acid. (2011) (49)
Addition of an α-Hydroxy Acid to the Genetic Code of Bacteria† (2008) (49)
Analysis of hydrogen bonding strengths in proteins using unnatural amino acids (1995) (49)
Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase‐Directed Library (2000) (49)
Photolithographic Immobilization of Biopolymers on Solid Supports (1992) (49)
Universal bases for hybridization, replication and chain termination. (2000) (48)
Drug repurposing screens identify chemical entities for the development of COVID-19 interventions (2021) (48)
An Antibody‐Mediated Redox Reaction (1988) (48)
Expanding the genetic repertoire of the methylotrophic yeast Pichia pastoris. (2009) (48)
A semisynthetic catalytic antibody (1989) (48)
Expanding the diversity of purine libraries (2001) (48)
Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA X Fe(II). (1983) (48)
Polymerase recognition of unnatural base pairs. (2002) (47)
Site-selective cleavage of RNA by a hybrid enzyme (1988) (47)
Design, synthesis, and activity of HDAC inhibitors with a N-formyl hydroxylamine head group. (2004) (47)
Alternative modes of substrate distortion in enzyme and antibody catalyzed ferrochelation reactions. (1998) (46)
Valence and atomic size dependent exchange barriers in vacancy-mediated dopant diffusion (1998) (46)
Protein-DNA photo-crosslinking with a genetically encoded benzophenone-containing amino acid. (2009) (46)
Generating New Molecular Function: A Lesson from Nature (1999) (46)
Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolution. (1996) (45)
Rapid dynamics of general transcription factor TFIIB binding during preinitiation complex assembly revealed by single-molecule analysis (2016) (45)
Loss of CD4 T-cell–dependent tolerance to proteins with modified amino acids (2011) (45)
Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin•Fe^(II)) and EDTA-bis(distamycin)•Fe^(II) (1983) (45)
Mutational analysis of the affinity maturation of antibody 48G7. (1999) (44)
Structural evidence for substrate strain in antibody catalysis (2003) (44)
The genetic incorporation of a distance probe into proteins in Escherichia coli. (2006) (44)
Evidence for interstitial hydrogen as the dominant electronic defect in nanometer alumina films. (2003) (44)
Directed mutagenesis of the redox-active disulfide in the flavoenzyme mercuric ion reductase. (1985) (43)
Simple intrinsic defects in gallium arsenide (2009) (43)
Small rings and amorphous tetrahedral carbon (1999) (43)
Catalytic antibodies: A new class of transition-state analogues used to elicit hydrolytic antibodies (1990) (43)
A Bacterial Strain with a Unique Quadruplet Codon Specifying Non‐native Amino Acids (2014) (43)
Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery (2016) (42)
Subcellular Protein Localization by Using a Genetically Encoded Fluorescent Amino Acid (2011) (42)
Structural and kinetic evidence for strain in biological catalysis. (1998) (42)
Targeted Delivery of LXR Agonist Using a Site-Specific Antibody-Drug Conjugate. (2015) (41)
A genetic approach to the generation of antibodies with enhanced catalytic activities. (1993) (41)
A chemically induced vaccine strategy for prostate cancer. (2011) (41)
Genetic Incorporation of ε-N-2-Hydroxyisobutyryl-lysine into Recombinant Histones. (2015) (41)
Characterization of an 'orthogonal' suppressor tRNA derived from E. coli tRNA2(Gln). (1997) (41)
Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. (2014) (41)
A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli. (2013) (41)
Low temperature annealing in tetrahedral amorphous carbon thin films observed by13C NMR spectroscopy (2003) (41)
Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins. (2016) (41)
Mechanistic Studies of an Antibody-Catalyzed Elimination Reaction (1994) (41)
A mutagenesis study of a catalytic antibody. (1991) (40)
Efficient expression of tyrosine-sulfated proteins in E. coli using an expanded genetic code (2009) (40)
Targeted Disruption of Myc-Max Oncoprotein Complex by a Small Molecule. (2017) (40)
Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors. (2001) (40)
One plasmid selection system for the rapid evolution of aminoacyl-tRNA synthetases. (2009) (40)
First-principles investigation of low energy E' center precursors in amorphous silica. (2011) (40)
PHOTOCHEMICALLY INITIATED PROTEIN SPLICING (1995) (40)
MECHANISTIC STUDIES OF ANTIBODY-CATALYZED PYRIMIDINE DIMER PHOTOCLEAVAGE (1995) (39)
2-Sulfonyl pyridines as tunable, cysteine-reactive electrophiles. (2020) (39)
A single mutation in the first transmembrane domain of yeast COX2 enables its allotopic expression (2010) (39)
Mutagenesis and evolution of sulfated antibodies using an expanded genetic code. (2009) (39)
Protein Crosslinking by Genetically Encoded Noncanonical Amino Acids with Reactive Aryl Carbamate Side Chains. (2017) (39)
Therapeutic Applications of an Expanded Genetic Code (2014) (39)
Activation Parameters and Stereochemistry of an Antibody‐Catalyzed Claisen Rearrangement (1992) (39)
Sequence-selective hydrolysis of duplex DNA by an oligonucleotide-directed nuclease (1989) (39)
Linear Free Energy Analysis of Hydrogen Bonding in Proteins (1995) (38)
A promiscuous aminoacyl-tRNA synthetase that incorporates cysteine, methionine, and alanine homologs into proteins. (2008) (38)
Conformational effects in biological catalysis: an antibody-catalyzed oxy-cope rearrangement. (2000) (37)
Redirecting the immune response: ligand-mediated immunogenicity (1991) (37)
Recruiting cytotoxic T cells to folate-receptor-positive cancer cells. (2013) (37)
A hybrid sequence-selective ribonuclease S (1988) (37)
Efforts toward the direct experimental characterization of enzyme microenvironments: tyrosine100 in dihydrofolate reductase. (2009) (36)
A concise and traceless linker strategy toward combinatorial libraries of 2,6,9-substituted purines. (2001) (36)
Regenerative phenotype in mice with a point mutation in transforming growth factor β type I receptor (TGFBR1) (2011) (36)
A potent and highly selective sulfotransferase inhibitor. (2002) (36)
Multiformat T-cell-engaging bispecific antibodies targeting human breast cancers. (2015) (36)
Synthesis of a cyclic urea as a nonnatural biopolymer scaffold (1996) (35)
Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids. (2018) (35)
Elucidating the molecular mechanism of cardiac remodeling using a comparative genomic approach. (2003) (35)
MOLECULAR ORIENTATION WITH VISIBLE LIGHT : REFLECTANCE-ANISOTROPY SPECTROSCOPY OF 3-THIOPHENE CARBOXYLATE ON CU(110) SURFACES (1998) (35)
The solid phase synthesis of N-alkylcarbamate oligomers (1996) (35)
A biochemical screen for GroEL/GroES inhibitors. (2014) (35)
Stepwise Chemically Induced Cardiomyocyte Specification of Human Embryonic Stem Cells (2011) (35)
Stabilizing and destabilizing effects of placing beta-branched amino acids in protein alpha-helices. (1994) (34)
Neratinib protects pancreatic beta cells in diabetes (2019) (34)
Antibody catalysis of peptide bond formation. (1994) (34)
Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections (2019) (34)
GroEL/ES inhibitors as potential antibiotics. (2016) (34)
The combinatorial synthesis and evaluation of functional materials (1997) (33)
Direct studies of 1,1-diazenes. Syntheses, infrared and electronic spectra, and kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene (1982) (33)
Site-specific mutagenesis with unnatural amino acids. (1989) (33)
An Antibody-Catalyzed Oxy-Cope Rearrangement (1994) (33)
Genetic introduction of a diketone-containing amino acid into proteins. (2006) (33)
Probing the role of loop 2 in Ras function with unnatural amino acids. (1993) (32)
Resin-capture and release strategy toward combinatorial libraries of 2,6,9-substituted purines. (2002) (32)
Synthetase polyspecificity as a tool to modulate protein function. (2011) (32)
Enzymatic phosphorylation of unnatural nucleosides. (2002) (32)
Generation of a catalytic sequence-specific hybrid DNase. (1989) (32)
Unusual Structural Relaxation for Rare-Earth Impurities in Sapphire: Ab Initio Study of Lanthanum (1998) (32)
The nature of multiple bonds. 1. .sigma.,.pi. Bonds versus bent bonds, a computational survey (1993) (32)
Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists (2015) (31)
Energetic Analysis of an Engineered Cation−π Interaction in Staphylococcal Nuclease (1998) (31)
Site‐Specific in vivo Labeling of Proteins for NMR Studies (2005) (31)
Solid-phase synthesis of 2,3,5-trisubstituted indoles. (2001) (31)
Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models. (2018) (31)
Design of Potent and Proteolytically Stable Oxyntomodulin Analogs. (2016) (31)
Lessons from the Immune System: From Catalysis to Materials (1996) (31)
IN02, a positive regulator of lipid biosynthesis, is essential for the formation of inducible membranes in yeast. (2002) (31)
Evolution of Iron(II)‐Finger Peptides by Using a Bipyridyl Amino Acid (2014) (31)
Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids. (2017) (31)
Small-molecule switches for zinc finger transcription factors. (2003) (30)
First principles site occupation and migration of hydrogen, helium, and oxygen in β-phase erbium hydride (2008) (30)
Ab initio calculations of adsorbate hydrogen-bond strength : ammonia on Pt(111) (1996) (30)
Rational Design of CXCR4 Specific Antibodies with Elongated CDRs (2014) (29)
Identification of metal ion binding peptides containing unnatural amino acids by phage display. (2013) (29)
Functional antibody CDR3 fusion proteins with enhanced pharmacological properties. (2013) (29)
A new strategy to photoactivate green fluorescent protein. (2010) (29)
Antibody-Catalyzed Retro-Aldol Reaction (1996) (29)
Dual regulation of hepatitis C viral RNA by cellular RNAi requires partitioning of Ago2 to lipid droplets and P-bodies. (2011) (29)
Trapping a transition state in a computationally designed protein bottle (2015) (29)
Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA). (2018) (29)
Genomic effects of polyamide/DNA interactions on mRNA expression. (2002) (29)
Antibody-catalyzed bimolecular imine formation (1991) (28)
The nature of multiple bonds. 2. Significance of the perfect-pairing approximation (1993) (28)
Antibody catalysis by transition state stabilization. (1987) (28)
K–CO on transition metals: A local ionic interaction (1987) (28)
Defect level distributions and atomic relaxations induced by charge trapping in amorphous silica (2012) (28)
Targeted Delivery of an Anti-inflammatory PDE4 Inhibitor to Immune Cells via an Antibody-drug Conjugate. (2016) (28)
Structural characterization of a p-acetylphenylalanyl aminoacyl-tRNA synthetase. (2005) (28)
Large-scale analysis of the human and mouse (2002) (28)
Trapping of the C5 Methylene Intermediate in Thymidylate Synthase (1998) (27)
Small molecule-based approaches to adult stem cell therapies. (2013) (27)
Stereospecific antibody-catalyzed reduction of an .alpha.-keto amide (1992) (27)
Calculations of systematics in B2 structure 3d transition metal aluminides (1993) (27)
Analysis of Backbone Hydrogen Bonding in a β-Turn of Staphylococcal Nuclease (1997) (27)
A Photochemical Switch for Controlling Protein-Protein Interactions. (1998) (27)
Stepwise chemically induced cardiomyocyte specification of human embryonic stem cells. (2011) (27)
Localization of GroEL determined by in vivo incorporation of a fluorescent amino acid. (2011) (27)
A new tool for studying protein structure and function (1994) (26)
Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant (2016) (26)
Mechanistic studies of a tyrosine-dependent catalytic antibody. (1991) (26)
A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water. (2003) (26)
Isoabzymes: structurally and mechanistically similar catalytic antibodies from the same immunization. (1993) (26)
A rugged energy landscape mechanism for trapping of transmembrane receptors during endocytosis. (2003) (26)
An Efficient Antibody-Catalyzed Oxygenation Reaction (1994) (26)
Engineering yeast endosymbionts as a step toward the evolution of mitochondria (2018) (25)
Bonding and brittleness in B2 structure 3d transition metal aluminides:; Ionic, directional, or does it make a difference (1992) (25)
Small molecule selectively suppresses MYC transcription in cancer cells (2017) (25)
A biosynthetic approach for the incorporation of unnatural amino acids into proteins. (1998) (25)
Introduction of a metal-dependent regulatory switch into an enzyme. (1989) (25)
Targeting the HSP60/10 chaperonin systems of Trypanosoma brucei as a strategy for treating African sleeping sickness. (2016) (25)
Fast through-bond diffusion of nitrogen in silicon (2001) (25)
Functional Replacement of Histidine in Proteins To Generate Noncanonical Amino Acid Dependent Organisms. (2018) (25)
Sensitive, multiplex and direct quantification of RNA sequences using a modified RASL assay (2014) (25)
Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli. (2004) (25)
Genetically Encoded Fluorescent Probe for Detecting Sirtuins in Living Cells. (2017) (25)
Generalized valence bond description of the bonding in [1.1.1]propellane (1986) (25)
Phage selection for site-specific incorporation of unnatural amino acids into proteins in vivo. (2001) (24)
A catalysis-based selection for peroxidase antibodies with increased activity. (2004) (24)
An antibody CDR3-erythropoietin fusion protein. (2013) (24)
Synthesis and Screening of Linear and Cyclic Oligocarbamate Libraries. Discovery of High Affinity Ligands for GPIIb/IIIa (1998) (24)
An antibody with a variable-region coiled-coil "knob" domain. (2014) (24)
Structural basis for the recognition of para-benzoyl-L-phenylalanine by evolved aminoacyl-tRNA synthetases. (2007) (24)
A genetically encoded metallocene containing amino acid (2007) (24)
A Genetically Encoded Direct Sensor of Antibody–Antigen Interactions (2009) (23)
Porphyrin distortion during affinity maturation of a ferrochelatase antibody, monitored by Resonance Raman spectroscopy. (2004) (23)
Theoretical evidence for “bent bonds” in the co2 molecule (1986) (22)
A short ORF-encoded transcriptional regulator (2021) (22)
Site-specific cleavage of duplex DNA with a. lambda. repressor-staphylococcal nuclease hybrid (1990) (22)
Site-selective cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid. (1989) (22)
A versatile linkage strategy for solid-phase synthesis of N,N-dimethyltryptamines and beta-carbolines. (2002) (22)
Photochemistry of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene, dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene (1982) (22)
A Single Functional Group Substitution in C5a Breaks B Cell and T Cell Tolerance and Protects Against Experimental Arthritis (2014) (21)
Rational design of a humanized glucagon-like peptide-1 receptor agonist antibody. (2015) (21)
Analysis of the Role of the Active Site Tyrosine in Human Glutathione Transferase A1-1 by Unnatural Amino Acid Mutagenesis (1998) (21)
An antibody-catalyzed dehydration reaction (1992) (21)
Dual Unnatural Amino Acid Incorporation and Click‐Chemistry Labeling to Enable Single‐Molecule FRET Studies of p97 Folding (2016) (21)
Progress toward an Antibody Glycosidase (1994) (21)
Applications of laser-polarized 129Xe to biomolecular assays. (2003) (20)
An antibody-catalyzed cis-trans isomerization reaction (1991) (20)
Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors. (2016) (20)
Antibody-catalyzed hydrolysis of phosphate monoesters (1991) (20)
A small interfering RNA screen for modulators of tumor cell motility identifies MAP 4 K 4 as a promigratory kinase (2006) (20)
New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice. (2020) (20)
Rational design of humanized dual-agonist antibodies. (2015) (20)
Phage-display evolution of tyrosine kinases with altered nucleotide specificity. (2001) (20)
Addition of an alpha-hydroxy acid to the genetic code of bacteria. (2008) (19)
A glycosidase antibody elicited against a chair-like transition state analog by in vitro immunization. (1998) (19)
Selecting folded proteins from a library of secondary structural elements. (2008) (19)
Site-specific recombination of asymmetric lox sites mediated by a heterotetrameric Cre recombinase complex. (2006) (19)
Synthesis and direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene. Comparison of five- and six-membered cyclic 1,1-dialkyldiazenes (1980) (19)
The effects of antibodies on stilbene excited-state energetics. (2006) (19)
Mechanical properties of metal dihydrides (2016) (19)
Antibody catalysis of peptidyl-prolyl cis-trans isomerization in the folding of RNase T1. (1998) (18)
Stereoselective Antibody-Catalyzed Oxime Formation (1994) (18)
A tumor-targeted immune checkpoint blocker (2019) (18)
Dose-rate dependence of radiation-induced interface trap density in silicon bipolar transistors (2006) (18)
Efficient hybrid evolutionary optimization of interatomic potential models. (2010) (18)
The nature of multiple bonds. 3. Benzene, bent bonds, and resonance (1993) (18)
Oral drug repositioning candidates and synergistic remdesivir combinations for the prophylaxis and treatment of COVID-19 (2020) (18)
Transcriptional Effects of the Potent Enediyne Anti-Cancer Agent Calicheamicin γ1I (2002) (18)
Replacement of Thymidine by a Modified Base in the Escherichia coli Genome. (2016) (18)
Small‐Molecule Regulators of Human Stem Cell Self‐Renewal (2011) (18)
A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer (2019) (17)
MECHANISTIC STUDIES OF AN ANTIBODY-CATALYZED PERICYCLIC REARRANGEMENT (1998) (17)
Density Functional Theory Study of the Geometry, Energetics, and Reconstruction Process of Si(111) Surfaces (2005) (17)
Engineering Protein Specificity: Gene Manipulation with Semisynthetic Nucleases (1991) (17)
Directed embryonic stem cell differentiation with small molecules. (2010) (17)
An image-based screen identifies a small molecule regulator of megakaryopoiesis (2012) (17)
Structure and band gaps of Ga-(V) semiconductors: The challenge of Ga pseudopotentials (2008) (16)
Site-Specific Incorporation of a Thioester Containing Amino Acid into Proteins (2018) (16)
The electronic transport mechanism in amorphous tetrahedrally-coordinated carbon films (1997) (16)
Replacement of 2'-Deoxycytidine by 2'-Deoxycytidine Analogues in the E. coli Genome. (2016) (16)
Mutational analysis of 48G7 reveals that somatic hypermutation affects both antibody stability and binding affinity. (2013) (16)
Tyrosine 146 of thymidylate synthase assists proton abstraction from the 5-position of 2'-deoxyuridine 5'-monophosphate. (1999) (16)
In vivo selection of basic region-leucine zipper proteins with altered DNA-binding specificities. (1996) (16)
Effects of basis set quality on the prediction of structures, energies, and properties of amorphous tetrahedral carbon (1998) (16)
Dorsomorphin promotes human embryonic stem cell self-renewal. (2011) (15)
A chromogenic assay for screening large antibody libraries (1992) (15)
An Antibody-Catalyzed Isomerization Reaction (1996) (15)
YAP-dependent proliferation by a small molecule targeting annexin A2 (2021) (15)
Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli. (2004) (15)
Photochemistry of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene (1981) (14)
A Metalloantibody That Irreversibly Binds a Protein Antigen* (2007) (14)
A Strategy for Creating Organisms Dependent on Noncanonical Amino Acids. (2017) (14)
Role of tRNA Orthogonality in an Expanded Genetic Code (2014) (14)
Noncoded amino acid replacement probes of the aspartate aminotransferase mechanism. (1997) (14)
Rational design of antibody protease inhibitors. (2015) (14)
Identification and characterization of small-molecule inducers of epidermal keratinocyte differentiation. (2007) (14)
A permutational approach toward protein-DNA recognition. (1994) (14)
Generation of an Orthogonal Protein-Protein Interface with a Noncanonical Amino Acid. (2017) (14)
The electronic structure of the benzene molecule (1987) (14)
A comparative analysis of HGSC and Celera human genome assemblies and gene sets (2003) (14)
Reactivities of ultrathin alumina films exposed to intermediate pressures of H2O: Substrate-mediated mechanism for growth and loss of surface order (2007) (14)
A MODEL FOR HYDRIDE TRANSFER IN THYMIDYLATE SYNTHASE BASED ON UNNATURAL AMINO ACID MUTAGENESIS (1999) (13)
Small molecule mediated proliferation of primary retinal pigment epithelial cells. (2013) (13)
Comparative analysis of human genome assemblies reveals genome-level differences. (2002) (13)
The scope of antibody catalysis. (1995) (12)
Stabilizing Protein Motifs with a Genetically Encoded Metal-Ion Chelator. (2016) (12)
Design of catalytic antibodies. (1989) (12)
Analysis of hapten binding and catalytic determinants in a family of catalytic antibodies. (1998) (12)
Homogeneously modified immunoglobulin domains for therapeutic application. (2015) (11)
Unconstrained and constrained minimization, localization, and the Grassmann manifold: Theory and application to electronic structure (2001) (11)
A valence bond theory of off-center impurities in silicon (1984) (11)
Antibody catalysis of pericyclic reactions. (1996) (11)
A mutational study of a Diels-Alderase catalytic antibody. (1999) (11)
A general strategy for engineering noncanonical amino acid dependent bacterial growth. (2019) (11)
Probing the role of lysine 16 in ras p21 protein with unnatural amino acids (1993) (11)
BaO/W(100) thermionic emitters and the effects of Sc, Y, La, and the density functional used in computations (2004) (10)
An Epitope-Specific Respiratory Syncytial Virus Vaccine Based on an Antibody Scaffold. (2015) (10)
Bringing biological solutions to chemical problems. (1998) (10)
A Novel Role for RARα Agonists as Apolipoprotein CIII Inhibitors Identified from High Throughput Screening (2017) (10)
Versatile fluorescence labeling method using activated esters on solid support. (1999) (10)
Eupalinilide E inhibits erythropoiesis and promotes the expansion of hematopoietic progenitor cells. (2013) (10)
Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity. (2020) (10)
A PSMA-targeted bispecific antibody for prostate cancer driven by a small-molecule targeting ligand (2021) (10)
Differentiation of mesenchymal stem cells (2010) (10)
Phage display of catalytically active staphylococcal nuclease. (1994) (10)
Development of a high-throughput screen for protein catalysts: application to the directed evolution of antibody aldolases. (2003) (9)
Commentary on combinatorial chemistry (2003) (9)
Incorporation of the unnatural amino acid p-benzoyl-L-phenylalanine (Bpa) into a G protein-coupled receptor in its native context. (2009) (9)
Modeling charged defects inside density functional theory band gaps (2013) (9)
[17] Catalytic antibodies (1991) (9)
The Scripps Research Institute (La Jolla, CA) (2010) (9)
Semi-synthesis of a Bacterium with Non-Canonical Cell Wall Crosslinks. (2020) (9)
A Single Reactive Noncanonical Amino Acid Is Able to Dramatically Stabilize Protein Structure. (2019) (8)
Catalysis of carbamate Hydrolysis by an antibody (1994) (8)
DIET in the bulk: evidence for hot electron cleavage of SiH bonds in SiO2 films (1997) (8)
Engineering Bifunctional Antibodies with Constant Region Fusion Architectures. (2017) (8)
Bacterial Genome Containing Chimeric DNA-RNA Sequences. (2018) (8)
Purine-Based Inhibitors of Inositol1,4,5-trisphosphate-3-kinase (2010) (8)
A novel inhibitor of inducible NOS dimerization protects against cytokine‐induced rat beta cell dysfunction (2018) (8)
An Antibody-Catalyzed [2,3]-Elimination Reaction (1996) (8)
Transcriptional effects of the potent enediyne anti-cancer agent Calicheamicin gamma(I)(1). (2002) (8)
Discriminating a deep gallium antisite defect from shallow acceptors in GaAs using supercell calculations (2016) (8)
Cyclic and linear oligocarbamate ligands for human thrombin. (1999) (8)
An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli. (2020) (8)
Effects of nitrogen on the interface density of states distribution in 4H-SiC metal oxide semiconductor field effect transistors: Super-hyperfine interactions and near interface silicon vacancy energy levels (2018) (8)
Shift in XPS levels in ionic adsorbate layers due to electrostatic effects (1989) (7)
Spontaneous ionization of hydrogen atoms at the Si-SiO2 interface. (2004) (7)
1,4,5-trisphosphate-3-kinase (2002) (7)
Site-directed spin labeling of a genetically encoded unnatural amino acid (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 51 (21637-21642)) (2010) (7)
Structure of the Michaelis Complex of an Efficient Antibody Acyl Transferase Determined by Transferred Nuclear Overhauser Enhancement Spectroscopy (1998) (7)
Construction and Screening of a Lentiviral Secretome Library. (2017) (7)
Euphohelioscopin A is a PKC activator capable of inducing macrophage differentiation. (2012) (7)
Activities of recombinant human bleomycin hydrolase on bleomycins and engineered analogues revealing new opportunities to overcome bleomycin-induced pulmonary toxicity. (2018) (7)
Toward understanding photoemission in K+CO coadsorption systems (1990) (6)
A small molecule inhibitor of alpha4 integrin-dependent cell migration. (2009) (6)
Identification and Characterization of Small‐Molecule Inducers of Fetal Hemoglobin (2011) (6)
Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis (2021) (6)
Visualization of the Delivery and Release of Small RNAs Using Genetic Code Expansion and Unnatural RNA-Binding Proteins. (2018) (6)
SELECTIVE ANTIBODY-CATALYZED SOLVOLYSIS OF ENDO-2-NORBORNYL MESYLATE (1999) (6)
Electrical effects of transient neutron irradiation of silicon devices (2007) (6)
Expanding the genetic code of the human hematopoietic system (2020) (6)
Generalized valence bond description of multiple bonds (1988) (6)
Probing the structural determinants of a catalytic RNA with isomerase activity (1995) (5)
Development of KA34 as a cartilage regenerative therapy for Osteoarthritis (2020) (5)
Towards a synthetic yeast endosymbiont with a minimal genome. (2019) (5)
Expanding the Diversity of Purine Libraries. (2002) (5)
Synthesis of diverse ethoxyformacetal oligomers. Toward libraries of metal-coordinating unnatural biopolymers (1997) (5)
Antibody-catalysed glycosyl transfer reactions from in vitro immunization (1997) (5)
A metabolite-derived protein modification integrates glycolysis with KEAP1–NRF2 signalling (2018) (5)
An Antibody-Catalyzed Bimolecular Diels-Alder Reaction. (1991) (5)
The E1–E2 center in gallium arsenide is the divacancy (2015) (5)
Towards the Generation of Artificial O6‐Alkylguanine‐DNA Alkyltransferases: In Vitro Selection of Antibodies with Reactive Cysteine Residues (2002) (5)
Modeling Thermal Abuse in Transportation Batteries (2012) (5)
Impact of Incorporation Kinetics on Device Fabrication with Atomic Precision (2021) (5)
Discovery and SAR studies of 3-amino-4-(phenylsulfonyl)tetrahydrothiophene 1,1-dioxides as non-electrophilic antioxidant response element (ARE) activators. (2021) (4)
Building blocks for peptide and carbamate libraries (1996) (4)
Retraction of "Mutational Analysis of 48G7 Reveals that Somatic Hypermutation Affects Both Antibody Stability and Binding Affinity". (2013) (4)
Corrigendum: A Genetically Encoded ε‐N‐Methyl Lysine in Mammalian Cells (2010) (4)
The impact of stochastic incorporation on atomic-precision Si:P arrays (2021) (4)
Theoretical study of intrinsic defects in cubic silicon carbide 3C -SiC (2021) (4)
Directed evolution of the substrate specificities of a site-specific recombinase and an aminoacyl-tRNA synthetase using fluorescence-activated cell sorting (FACS). (2003) (4)
A New Strategy for Creating Noncanonical Amino Acid Dependent Organisms (2017) (4)
A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure. (2019) (4)
Catalytic antibodies. (1990) (4)
First-principles calculations of metal surfaces. II. Properties of low-index platinum surfaces toward understanding electron emission (2021) (4)
Simple intrinsic defects in GaAs : numerical supplement. (2012) (4)
Off-center Tl and Na dopant centers in CsI (2013) (4)
Rational Design of Dual Agonist-Antibody Fusions as Long-acting Therapeutic Hormones. (2016) (4)
Defect reaction network in Si-doped GaAs : numerical predictions. (2012) (3)
ANTIBODIES WITH THIOL-S-TRANSFERASE ACTIVITY (1996) (3)
News Members of the Editorial Board and International Advisory Board. (2016) (3)
Sequence-specific double-strand cleavage of DNA by bis(EDTA-distamycin.iron(II)) and EDTA-bis(distamycin).iron(II) (1983) (3)
The generation of antibody combining sites containing catalytic residues. (1991) (3)
Antibody Catalysis of Difficult Chemical Transformations. (1993) (3)
First principles (Density Functional Theory) calculations on ErT2(111) He bubble surfaces. (2005) (3)
Recent advances in catalytic antibodies. (1991) (3)
Site-specific Incorporation of a Dithiolane Containing Amino Acid into Proteins. (2019) (3)
Adding new chemistries to the central dogma of molecular biology (2021) (3)
Adaptive wideband optical nulling for an antenna system (1994) (3)
Modelling challenges for battery materials and electrical energy storage (2013) (3)
Small‐Molecule Stimulators of NRF1 Transcriptional Activity (2020) (3)
The Chemistry of the Antibody Molecule (2003) (3)
First-principles calculations of metal surfaces. I. Slab-consistent bulk reference for convergent surface properties (2021) (2)
Erratum: Small-molecule synergist of the Wnt/β-catenin signaling pathway (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 18, (7444-7448) DOI: 10.1073/pnas.0702136104) (2007) (2)
Simulation and modeling of the electronic structure of GaAs damage clusters (2012) (2)
Self-Renewal of Hematopoietic Stem Cells by a Small Molecule (2008) (2)
First Principles Predictions of Intrinsic Defects in Aluminum Arsenide, AlAs (2011) (2)
Erratum: Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (Proceedings of the National Academy of Sciences of the United States of America (2013) 27:110 (E2510-E2517)) (2013) (2)
Automated Algorithms for Quantum-Level Accuracy in Atomistic Simulations: LDRD Final Report. (2012) (2)
Crystal structure of sulfo-hirudin complexed to thrombin (2007) (2)
Chemical Control of Stem Cell Fate and Developmental (2011) (2)
Progress toward a reduced phage genetic code. (2018) (2)
1,1′Carbonylbis(3-methylimidazolium) Triflate: An Efficient Reagent for Aminoacylations. (1989) (2)
Stereospecific Antibody-Catalyzed Reduction of an α-Keto Amide. (1992) (2)
Bridging Scales from Ab Initio Models to Predictive Empirical Models for Complex Materials (2008) (2)
Temporal fluctuations in single molecule dipole orientation and single molecule energy transfer as a probe for protein conformational dynamics (1998) (2)
in vivo alkynyl amino acids to proteins in eubacteria incorporation (2005) (2)
A Genetically Encoded Boronate Amino Acid (2010) (2)
Simple intrinsic defects in InP : numerical predictions. (2012) (2)
A Unified Computational Approach to Oxide Aging Processes (1999) (2)
A synthetic 5,3-cross-link in the cell wall of rod-shaped Gram-positive bacteria (2021) (2)
The Interplay between Chemistry and Biology in the Design of Enzymatic Catalysts (1988) (2)
Stereospecific Hydrolysis of Alkyl Esters by Antibodies. (1989) (2)
Insights into antibody catalysis : Structure of an oxygenation catalyst at 1 . 9A resolution ( crystal structure / catalytic antibody / oxidation ) (2005) (2)
Catalytic antibodies. (1991) (1)
Photosensitized Cleavage of a Thymine Dimer by an Antibody. (1989) (1)
The genetic incorporation of p-azidomethyl-l-phenylalanine into proteins in yeast. (2018) (1)
RNA Catalysis and Transition State Stabilization (1996) (1)
An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli (2020) (1)
Antibody‐Catalyzed Hydrolysis of Phosphate Monoesters. (1992) (1)
Monoclonal antibodies with sequence specific affinity for a stem - loop structure in DNA (1991) (1)
Structural Studies of Catalytic Antibodies (1996) (1)
A Mechanism for Enhanced Low-Dose-Rate Sensitivity of Bipolar Transistors (2000) (1)
Effects of 4.5 MeV and 63 MeV proton irradiation on carrier lifetime of InAs/InAsSb type-II superlattices (Conference Presentation) (2017) (1)
Simple intrinsic defects in InAs (2013) (1)
Development of a genetic selection for catalytic antibodies. (2002) (1)
In Vivo Incorporation of Unnatural Amino Acids into Proteins (2000) (1)
RASLseqTools: open-source methods for designing and analyzing RNA-mediated oligonucleotide Annealing, Selection, and, Ligation sequencing (RASL-seq) experiments (2016) (1)
for crystal formation (2002) (1)
Development of novel sterol-based Liver X Receptor agonists as therapeutics for inflammatory diseases (HUM1P.307) (2015) (1)
A940 Does training in a full scale anesthesia simulator improve residents' performance? (1997) (1)
Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (vol 110, pg E2510, 2013) (2013) (1)
Catalytic antibodies. (1996) (1)
P-262 A PDE4 Inhibitor-antibody Conjugate for Treating Ulcerative Colitis (2017) (1)
Current understanding of the oxygen vacancy in SiO2 and its role in radiation effects in the MOS system. (2004) (1)
An Antibody-Mediated Redox Reaction. (1988) (1)
First in Human Study of an on/Off Switchable CAR-T Cell Platform Targeting CD19 for B Cell Malignancies (CLBR001 + SWI019) (2021) (1)
Density functional theory study of the geometry, energetics, and reconstruction process of Si111 surfaces. (2005) (1)
Kartogenin promotes mouse embryo limb joint formation and skeletal growth (2013) (0)
Recent Advances in Catalytic Antibodies (1993) (0)
Combinatorial hydrothermal synthesis of new materials (1995) (0)
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase (2008) (0)
Crystal Structure of a Copper-Mediated Base Pair in DNA (2001) (0)
Synthesis at the Interface of Chemistry and Biology (2014) (0)
Nondestructive Imaging of Periodic Structures of Dielectric Constant and Ferroelectric Domains by a Scanning Tip Microwave Near-field Microscope (1997) (0)
Crystal structure of p-bromo-l-phenylalanine-tRNA sythetase in complex with p-bromo-l-phenylalanine (2006) (0)
MUTAGENESIS WITH AN EXPANDED GENETIC CODE (1995) (0)
Thermodynamic and Binding Effects of Antibody Affinity Maturation (2014) (0)
Probing Ras function with unnatural amino acids (1994) (0)
MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN (1999) (0)
Fabrication Issues in Combinatorial Synthesis of Metal Oxide Thin Film and Device Libraries (1998) (0)
IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY (1997) (0)
Design and Synthesis of Semisynthetic Enzymes. (1987) (0)
Activation Parameters and Stereochemistry of an Antibody-Catalyzed Claisen Transformation (1992) (0)
Novel Biopolymeric Materials. (1996) (0)
UNLIGANDED MATURE OXY-COPE CATALYTIC ANTIBODY (2000) (0)
Preview: ChemBioChem 10/2002 (2002) (0)
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT (1996) (0)
Building Blocks for Peptide and Carbamate Libraries. (1997) (0)
I. Ground and Excited State Studies of Persistent 1,1-Diazenes. II. Design of Sequence Specific DNA Cleaving Molecules (1984) (0)
THE UNLIGANDED GERMLINE PRECURSOR TO THE SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4. (2001) (0)
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 (2004) (0)
Clearance of A2E From RPE Cells by Select Lysosomotropes (2010) (0)
Enzyme engineering for biodegradation of chlorinated organic pollutants. 1997 annual progress report (1997) (0)
Dual-channel Raman investigation of porphyrin binding to anti-porphyrin antibody (1992) (0)
Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli : V216AcrF mutant (2015) (0)
Effects of YAP small molecule activators on human neural crest stem cells and corneal endothelial cells (2017) (0)
MicroRNA 1915 modulate insulin signalling pathway by suppressing of DNAJ Heat Shock Protein Family ( Hsp 40 ) Member B 3 ( DNAJB 3 ) expression (2019) (0)
Erratum: Identification of small-molecule inducers of pancreatic β-cell expansion (Proceedings of the National Academy of Sciences of the United States of America (2009) 106 (1427-1432)) (2009) (0)
Antibody Catalysis in Reverse Micelles. (1989) (0)
Combinatorial Sythese of new materials (1995) (0)
Characterization of the mechanism of action of a catalytic antibody. (1991) (0)
crystal structure of apo M. jannashii tyrosyl-tRNA synthetase (2005) (0)
A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts (chemical librariesycell cycle) (1999) (0)
48G7 HYBRIDOMA LINE FAB COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID (1996) (0)
DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR (1998) (0)
FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY (1997) (0)
catalytic antibody 21h3 (2004) (0)
One‐Pot Two‐Step Microwave‐Assisted Reaction in Constructing 4,5‐Disubstituted Pyrazolopyrimidines. (2004) (0)
Correction for A small molecule accelerates neuronal differentiation in the adult rat, by Heiko Wurdak, Shoutian Zhu (2010) (0)
Location-spicifik inkorporing of redox-active amino acids in protiener (2004) (0)
Crystal Structure of p-acetylphenylalanine-tRNA synthetase in complex with p-acetylphenylalanine (2006) (0)
Compositions of the orthogonal lysyl tRNA and aminoacyl-tRNA synthetase pairs and their uses (2004) (0)
genetically programmed protein expression selectively sulfated in eubacteria (2007) (0)
Screening of organometallic compounds for catalysis (1995) (0)
10 Artificial Nucleases (1993) (0)
mRNA expression profile of a human cancer cell line in response to a phytochemical extract with antioxidant properties (1999) (0)
A Catalytic Antibody for Hydrolysis of Peptides (1998) (0)
Synthesis of Diverse Ethoxyformacetal Oligomers. Toward Libraries of Metal-Coordinating Unnatural Biopolymers. (1998) (0)
A study of a catalytic antibody. (2008) (0)
Catalytic Antibodies: A New Class of Transition‐State Analogues Used to Elicit Hydrolytic Antibodies (1991) (0)
Chimeric Mature Fab 7g12-Apo (2003) (0)
IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY (1997) (0)
Crystal Structure of L-3-(2-napthyl)alanine-tRNA synthetase in complex with L-3-(2-napthyl)alanine (2006) (0)
Characterization of a novel cdk inhibitor using Xenopus egg extracts. (1998) (0)
Progress Toward an Antibody Glycosidase. (2010) (0)
Catalytic Antibody 21H3 with alcohol substrate (2004) (0)
A chemistry-based approach to identify factors involved in spindle assembly (1999) (0)
Catalytic Antibody 21H3 with hapten (2004) (0)
Approaches to the design of semisynthetic metal-dependent catalytic antibodies. (1991) (0)
Enzyme engineering for biodegradation of chlorinated organic pollutants (1998) (0)
Sequence-specific double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA * Fe ( II ) ( minor groove binding / netropsin / distamycin / restriction enzymes ) (1999) (0)
BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE (2004) (0)
Patent Number : 5 , 429 , 936 45 ) Date of Patent : Jul . 4 , 1995 Antibodies : The Claisen Rearrangement ' , Proc (2017) (0)
Crystal structure of a p-benzoyl-L-phenylalanyl-tRNA synthetase (2007) (0)
A sulfide oxidation catalytic antibody (1996) (0)
Germline 7G12 with N-methylmesoporphyrin (2003) (0)
Chimeric Germline Fab 7g12-apo (2003) (0)
Semisynthetic Catalytic Antibodies (1990) (0)
HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B (1999) (0)
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO] METHYLPHOSPHONIC ACID) (1996) (0)
Cover Picture: Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding (ChemBioChem 11/2016) (2016) (0)
Synthesis of a Cyclic Urea as a Nonnatural Biopolymer Scaffold. (1996) (0)
Methods and compositions for the production of orthogonal tRNA pairs of aminoacyl-tRNA synthetase (2002) (0)
The Protective Effects of Betaine Against DSS-induced Colitis (2017) (0)
Applications of Genetically Encoded Unnatural Amino Acids for Protein Structure Mapping by Site-Directed Spin Labeling (2011) (0)
Combinatorial synthesis of new materials (1995) (0)
THE HAPTEN COMPLEXED GERMLINE PRECURSOR TO SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4 (2001) (0)
Probing a catalytic antibody active site using spin-labelled haptens (1993) (0)
Hybrid Enzymes and the Sequence-Specific Cleavage of Nucleic Acids (1991) (0)
IND-Enabling Studies of a Switchable Chimeric Antigen Receptor-T Cell (CLBR001+SWI019) to Support First in Human Clinical Study (2021) (0)
Abstract 3904: Overcoming resistance to HER2 inhibitors through cell based screening (2016) (0)
Kristen Johnson Based Approach to Cartilage Repair − A Stem Cell (2012) (0)
Supplementary Materials for Genomically Recoded Organisms Expand Biological Functions (2013) (0)
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof (2017) (0)
Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, F42W, Y79A, and F123Y mutant (2015) (0)
UNLIGANDED GERMLINE PRECURSOR OF AN OXY-COPE CATALYTIC ANTIBODY (2000) (0)
Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant. (2015) (0)
A Small Molecule Inhibitor of α 4 Integrin-Dependent Cell Migration (2010) (0)
Crystal Structure of T4 lysozyme with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 131 (2009) (0)
An Antibody-Catalyzed Reduction of Ketone (1998) (0)
Chimeric Germline Fab 7g12 with jeffamine fragment bound (2003) (0)
Embryonic stem cells Ectoderm Mesoderm Endoderm Neurons Pigment cells Skin cells Cardiomyocytes Hematopoietic cells Muscle cells Hepatocytes Pancreatic cells Lung cells Embryonic stem cells Germ layer progenitors Tissue-specific cells Self-renewal Self-renewal Differentiation Differentiation Special (0)
Corrigendum to “Development of a Genetic Selection for Catalytic Antibodies” [Bioorg. Med. Chem. Lett. 12 (2002) 1691]† (2002) (0)
Sub-micron Non-contact Conductivity and Dielectric Constant Imaging by Scanning Near Field Microwave Microscope (1997) (0)
A mutagenesis study of a catalytic antibody (antibody catalysis/phosphocholine/mutages) (1991) (0)
crystal structure of a mutant M. jannashii tyrosyl-tRNA synthetase specific for O-methyl-tyrosine (2005) (0)
CONFORMATION EFFECTS IN BIOLOGICAL CATALYSIS INTRODUCED BY OXY-COPE ANTIBODY MATURATION (2000) (0)
Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin (2003) (0)
Antibody Catalysis of Pericyclic Reactions (1996) (0)
Lysyl-tRNA compositions and orthogonal aminoacyl-tRNA synthetase pairs and uses thereof. (2004) (0)
Boitano Human Hematopoietic Stem Cells Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of (2012) (0)
Antibody-Catalyzed Glycosyl Transfer Reactions from in vitro Immunization. (1998) (0)
DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE (1998) (0)
Crystal Structure T4 Lysozyme incorporating an unnatural amino acid p-iodo-L-phenylalanine at position 153 (2004) (0)
Jonathan Ellman (2018) (0)
Provide specific installation of ketoaminosäuren in proteins (2003) (0)
Meister Antimalarial Drug Discovery Liver Stages to Drive Next-Generation Plasmodium Imaging of (2012) (0)
Ab-Initio TCAD Models of Dopant Diffusion in Silicon (1999) (0)
Atomically Precise Single Donor Placement by STM Lithography. (2016) (0)
Roles of Oxygen in Crystalline GST and at the GST/TiAlN Interface (2007) (0)
Generating structural models of amorphous tetrahedral carbon: basis set dependencies (1997) (0)
Unconstrained and Constrained Minimization, Linear Scaling, and the Grassmann Manifold: Theory and Applications (2000) (0)
Interaction of Hydrogen with Silicon-Silicon Dioxide Interfaces (2005) (0)
Response to Comment on 'Theory of Defect Levels and the %22Band Gap Problem%22 in SIlicon'. (2008) (0)
Electron transport through self-assembled molecular monolayers (2003) (0)
First-principles simulations of GaAs defects: The challenge of Ga pseudopotentials (2008) (0)
The O vacancy in alpha-quartz: supercells and density functional theory (2003) (0)
Adapting DFT C6-corrections for modeling graphene on metal surfaces (2015) (0)
First principles predictions of intrinsic defects in aluminum arsenide, AlAs : numerical supplement. (2012) (0)
Nitrogen in silicon: Fast diffusion through a purely interstitialcy mechanism (2001) (0)
Synthesis and biological evaluation of novel FiVe1 derivatives as potent and selective agents for the treatment of mesenchymal cancers. (2022) (0)
Multiphoton dissociation of dimers by infrared laser irradiation (A) (1978) (0)
The journey from forensic to predictive materials science using density functional theory (2017) (0)
Retrofit of the HSE density functional. (2012) (0)
Development of an Analytical Bond Order Potential for Al-Cu-H Systems. (2013) (0)
Generalized Valence Bond Description of the Bonding in (1.1.1)Propellane. (1987) (0)
Electronic and geometric structure of transition-metal nanoclusters (1996) (0)
The role of the Ge vacancy in electron transport in GeTe (2004) (0)
Effects of 3He in ErT2. (2011) (0)
CSRF Interim Project Report: Current Topics in Density Functional Theory (2006) (0)
From density functional theory to defect level in silicon: Does the “band gap problem” matter? (2008) (0)
AMORPHOUS TETRAHEDRALLY-COORDINATED CARBON FILMS ~ , 4 4 ~ -9 7-/ 473 C (0)
Defect and Dopant Properties in CsI and NaI. (2012) (0)
First principles site occupation and migration of helium in Beta-phase erbium hydride. (2009) (0)
Modeling charged defects and defects levels in semiconductors and oxides with DFT: An improved inside-out perspective. (2015) (0)
Defect levels in semiconductors - is the “band gap problem” truly a problem? (2006) (0)
Computers and crystals on the connection between materials physics computing (1994) (0)
A model for proton generation at the Si-SiO2 Interface (2001) (0)
Supercell issues in density functional calculations (2005) (0)
Radiolytic Hydrogen Sources in Silicon Dioxide (2004) (0)
Correction to "Small-Molecule Inducer of β Cell Proliferation Identified by High-Throughput Screening" (2013) (0)
Thin Aluminum Oxide Films on a Metallic Substrate: LDA Results (1998) (0)
Atomic step disorder on polycrystalline surfaces leads to spatially inhomogeneous work functions (2021) (0)
Predicting growth of graphene nanostructures using high-fidelity atomistic simulations (2015) (0)
FIRST-PRINCIPLES DEFECT CHEMISTRY FOR MODELING IRRADIATED GaAs AND III-V SEMICONDUCTOR DEVICES. (2011) (0)
Accurate numerical integration of an electron exchange hole with a screened Coulomb interaction (2012) (0)
Crystal structure of a bipyridylalanyl-tRNA synthetase (2008) (0)
Density functional theory study of transition metal porphine adsorption on gold surface and electric field induced conformation changes. (2005) (0)
Optical remote measurement of temperature in the range 0 to 2000/sup 0/C (1974) (0)
Greetings from the new Editors-in-Chief (2016) (0)
The density functional theory defect band gap in GaAs (2010) (0)
Effects of 3He in ErT2 and Pd. (2012) (0)
The Sapphire (0001) Surface, Clean and with d-metal Overlayers: Density Functional - LDA Results (1998) (0)
Quantum mechanical studies of carbon structures (2015) (0)
Vacuum Field Emission Models Measurements and Simulations. (2017) (0)
Modelling Charged Defects in Non-Cubic Semiconductors for Radiation Effects Studies in Next Generation Materials (2018) (0)
Development of PIC-DSMC Model for Breakdown in the Presence of a Dielectric. (2015) (0)
Photoelectron spectroscopy and chemical bonding: valence bond model viewpoint (1989) (0)
Electronic structure of intrinsic defects in c -gallium nitride: Density functional theory study without the jellium approximation (2022) (0)
Simple intrinsic defects in GaP and InP (2012) (0)
Charge trap distributions and correlated atomic relaxations in amorphous silica. (2012) (0)
Massively parallel Gaussian-based local density functional calculations for large molecular systems (1993) (0)
Abstract Submitted for the MAR08 Meeting of The American Physical Society (2007) (0)
Interface Effects on Total Energy Calculations for Radiation-Induced Defects (2013) (0)
Theory of the metastable injection-bleached <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>E</mml:mi><mml:mn>3</mml:mn><mml:mi>c</mml:mi></mml:mrow></mml:math> center in GaAs (2022) (0)
The anaesthesia simulator as an educational tool: 55 (1997) (0)
STEM-20. A CANCER STEM CELL-SELECTIVE APOPTOSIS-INDUCING SMALL MOLECULE FOR THE TREATMENT OF GBM (2020) (0)
Special-Issue Preface (1986) (0)
A Novel Role for RARα Agonists as Apolipoprotein CIII Inhibitors Identified from High Throughput Screening (2017) (0)

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