Peter Hegemann
German biophysicist
Peter Hegemann's AcademicInfluence.com Rankings
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Physics
Peter Hegemann's Degrees
- PhD Physics University of Regensburg
Why Is Peter Hegemann Influential?
(Suggest an Edit or Addition)According to Wikipedia, Peter Hegemann is a Hertie Senior Research Chair for Neurosciences and a Professor of Experimental Biophysics at the Department of Biology, Faculty of Life Sciences, Humboldt University of Berlin, Germany. He is known for his discovery of channelrhodopsin, a type of ion channels regulated by light, thereby serving as a light sensor. This created the field of optogenetics, a technique that controls the activities of specific neurons by applying light. He has received numerous accolades, including the Rumford Prize, the Shaw Prize in Life Science and Medicine, and the Albert Lasker Award for Basic Medical Research.
Peter Hegemann's Published Works
Published Works
- Channelrhodopsin-2, a directly light-gated cation-selective membrane channel (2003) (2345)
- Neocortical excitation/inhibition balance in information processing and social dysfunction (2011) (1983)
- Channelrhodopsin-1: A Light-Gated Proton Channel in Green Algae (2002) (1024)
- Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms (2013) (740)
- Ultrafast optogenetic control (2010) (675)
- Bi-stable neural state switches (2009) (537)
- Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri (2008) (515)
- Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. (2005) (513)
- Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics (2013) (506)
- The Microbial Opsin Family of Optogenetic Tools (2011) (459)
- Crystal structure of the channelrhodopsin light-gated cation channel (2012) (458)
- High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels (2011) (376)
- A Streptomyces rimosus aphVIII gene coding for a new type phosphotransferase provides stable antibiotic resistance to Chlamydomonas reinhardtii. (2001) (359)
- Conversion of Channelrhodopsin into a Light-Gated Chloride Channel (2014) (321)
- Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil Bacterium Beggiatoa*♦ (2010) (315)
- A synthetic gene coding for the green fluorescent protein (GFP) is a versatile reporter in Chlamydomonas reinhardtii. (1999) (307)
- Active cortical dendrites modulate perception (2016) (273)
- Rhodopsin-regulated calcium currents in Chlamydomonas (1991) (255)
- Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling (2013) (252)
- Fast manipulation of cellular cAMP level by light in vivo (2007) (232)
- Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. (2003) (223)
- Optogenetic Tools for Subcellular Applications in Neuroscience (2017) (213)
- Algal sensory photoreceptors. (2008) (213)
- Phot-LOV1: photocycle of a blue-light receptor domain from the green alga Chlamydomonas reinhardtii. (2003) (197)
- Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics (2013) (195)
- Hydrogen-bond switching through a radical pair mechanism in a flavin-binding photoreceptor. (2006) (193)
- Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity (2015) (171)
- The form and function of channelrhodopsin (2017) (171)
- Monitoring Light-induced Structural Changes of Channelrhodopsin-2 by UV-visible and Fourier Transform Infrared Spectroscopy* (2008) (169)
- Channelrhodopsin-1 Initiates Phototaxis and Photophobic Responses in Chlamydomonas by Immediate Light-Induced Depolarization[W] (2008) (166)
- Channelrhodopsins: directly light-gated cation channels. (2005) (165)
- Targeting of Photoreceptor Genes in Chlamydomonas reinhardtii via Zinc-Finger Nucleases and CRISPR/Cas9 (2017) (156)
- Photoactivation of Channelrhodopsin* (2008) (155)
- Color-tuned Channelrhodopsins for Multiwavelength Optogenetics (2012) (154)
- A blue-light photoreceptor mediates the feedback regulation of photosynthesis (2016) (153)
- Biophysics of Channelrhodopsin. (2015) (147)
- Engineering of a red-light–activated human cAMP/cGMP-specific phosphodiesterase (2014) (144)
- Nuclear gene targeting in Chlamydomonas using engineered zinc-finger nucleases. (2013) (139)
- pH dependence of the absorption and emission behaviour of riboflavin in aqueous solution (2002) (136)
- Multiple photocycles of channelrhodopsin. (2005) (132)
- Monitoring dynamic expression of nuclear genes in Chlamydomonas reinhardtii by using a synthetic luciferase reporter gene (2005) (127)
- Chlamyrhodopsin represents a new type of sensory photoreceptor. (1995) (127)
- Photo-induced degradation of some flavins in aqueous solution (2005) (126)
- The abundant retinal protein of the Chlamydomonas eye is not the photoreceptor for phototaxis and photophobic responses. (2001) (125)
- On the reaction mechanism of adduct formation in LOV domains of the plant blue-light receptor phototropin. (2004) (120)
- "Vision" in single-celled algae. (2004) (116)
- Monitoring dynamic expression of nuclear genes in Chlamydomonas reinhardtii by using a synthetic luciferase reporter gene (2004) (114)
- Optogenetics: 10 years after ChR2 in neurons—views from the community (2015) (112)
- Fluorescence quenching of flavin adenine dinucleotide in aqueous solution by pH dependent isomerisation and photo-induced electron transfer (2003) (109)
- All-trans retinal constitutes the functional chromophore in Chlamydomonas rhodopsin. (1991) (108)
- Vision in microalgae (1997) (107)
- Optogenetic Acidification of Synaptic Vesicles and Lysosomes (2015) (102)
- Channelrhodopsin engineering and exploration of new optogenetic tools (2011) (101)
- In vitro identification of rhodopsin in the green alga Chlamydomonas. (1991) (97)
- The Photoreceptor Current of the Green Alga Chlamydomonas (1992) (95)
- The photocycle of the chloride pump halorhodopsin. II: Quantum yields and a kinetic model (1985) (95)
- Hydrogen bond switching among flavin and amino acid side chains in the BLUF photoreceptor observed by ultrafast infrared spectroscopy. (2008) (95)
- An improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo (2015) (92)
- A Photochromic Histidine Kinase Rhodopsin (HKR1) That Is Bimodally Switched by Ultraviolet and Blue Light* (2012) (92)
- The photocycle of the chloride pump halorhodopsin. I: Azidecatalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump (1985) (84)
- From channelrhodopsins to optogenetics (2013) (82)
- The nature of rhodopsin-triggered photocurrents in Chlamydomonas. I. Kinetics and influence of divalent ions. (1996) (82)
- Of ion pumps, sensors and channels - perspectives on microbial rhodopsins between science and history. (2014) (82)
- Controlling fertilization and cAMP signaling in sperm by optogenetics (2015) (80)
- In Channelrhodopsin-2 Glu-90 Is Crucial for Ion Selectivity and Is Deprotonated during the Photocycle* (2012) (80)
- Glu 87 of Channelrhodopsin‐1 Causes pH‐dependent Color Tuning and Fast Photocurrent Inactivation † (2009) (79)
- Nuclear-Gene Targeting by Using Single-Stranded DNA Avoids Illegitimate DNA Integration in Chlamydomonas reinhardtii (2005) (78)
- H+ -pumping rhodopsin from the marine alga Acetabularia. (2006) (77)
- Vibrational spectroscopy of an algal Phot-LOV1 domain probes the molecular changes associated with blue-light reception. (2003) (76)
- Evolution of the channelrhodopsin photocycle model. (2010) (75)
- Quantum yield of triplet formation of riboflavin in aqueous solution and of flavin mononucleotide bound to the LOV1 domain of Phot1 from Chlamydomonas reinhardtii (2003) (74)
- Spectroscopic Characterization of Flavin Mononucleotide Bound to the LOV1 Domain of Phot1 from Chlamydomonas reinhardtii¶ (2002) (73)
- In vivo generation of flavoproteins with modified cofactors. (2009) (72)
- Early formation of the ion-conducting pore in channelrhodopsin-2. (2015) (72)
- Towards an understanding of channelrhodopsin function: simulations lead to novel insights of the channel mechanism. (2013) (72)
- ALGAL SENSORY PHOTORECEPTORS (2001) (71)
- Fluoresence quenching of riboflavin in aqueous solution by methionin and cystein (2003) (71)
- The rhodopsin–guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling (2015) (69)
- The phot LOV2 domain and its interaction with LOV1. (2005) (69)
- Crystal structure of the red light-activated channelrhodopsin Chrimson (2018) (68)
- The role of key amino acids in the photoactivation pathway of the Synechocystis Slr1694 BLUF domain. (2009) (68)
- The branched photocycle of the slow-cycling channelrhodopsin-2 mutant C128T. (2010) (66)
- Removal of mismatched bases from synthetic genes by enzymatic mismatch cleavage (2005) (65)
- Absorption and fluorescence spectroscopic characterization of BLUF domain of AppA from Rhodobacter sphaeroides (2005) (65)
- Nuclear gene targeting in Chlamydomonas as exemplified by disruption of the PHOT gene. (2009) (64)
- Ion selectivity and competition in channelrhodopsins. (2013) (64)
- Two open states with progressive proton selectivities in the branched channelrhodopsin-2 photocycle. (2010) (63)
- Recording of blue light-induced energy and volume changes within the wild-type and mutated phot-LOV1 domain from Chlamydomonas reinhardtii. (2004) (63)
- REVERSIBLE BLEACHING OF Chlamydomonas reinhardtii RHODOPSIN in vivo (1988) (63)
- Photodynamics of the small BLUF protein BlrB from Rhodobacter sphaeroides. (2006) (62)
- Control of phobic behavioral responses by rhodopsin-induced photocurrents in Chlamydomonas. (1997) (61)
- Channelrhodopsins of Volvox carteri Are Photochromic Proteins That Are Specifically Expressed in Somatic Cells under Control of Light, Temperature, and the Sex Inducer[C][W] (2009) (60)
- Blue light induces global and localized conformational changes in the kinase domain of full-length phototropin. (2010) (60)
- Phototropin Influence on Eyespot Development and Regulation of Phototactic Behavior in Chlamydomonas reinhardtii[W] (2012) (58)
- Volvoxrhodopsin, a Light-Regulated Sensory Photoreceptor of the Spheroidal Green Alga Volvox carteri (1999) (56)
- Reconstitution of the light-driven electrogenic ion pump halorhodopsin in black lipid membranes (1984) (56)
- Rectification of the channelrhodopsin early conductance. (2011) (55)
- Light‐induced stop response in Chlamydomonas reinhardtii: Occurrence and adaptation phenomena (1989) (53)
- Two light-activated conductances in the eye of the green alga Volvox carteri. (1999) (51)
- Irreversible photoreduction of flavin in a mutated Phot-LOV1 domain. (2003) (51)
- Evidence for a light-induced H(+) conductance in the eye of the green alga Chlamydomonas reinhardtii. (2002) (51)
- Potassium channel-based optogenetic silencing (2018) (51)
- Bimodal Activation of Different Neuron Classes with the Spectrally Red-Shifted Channelrhodopsin Chimera C1V1 in Caenorhabditis elegans (2012) (51)
- Structural Model of Channelrhodopsin* (2012) (50)
- Photo-dynamics of roseoflavin and riboflavin in aqueous and organic solvents (2009) (50)
- Functional variations among LOV domains as revealed by FT-IR difference spectroscopy. (2004) (49)
- Light-dark Adaptation of Channelrhodopsin C128T Mutant* (2013) (48)
- Direct measurement of cytosolic calcium and pH in living Chlamydomonas reinhardtii cells. (1999) (47)
- Microbial opsins: a family of single-component tools for optical control of neural activity. (2011) (47)
- Identification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin from Proteomonas sulcata* (2016) (47)
- Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior (2017) (46)
- Characterization of a flavin radical product in a C57M mutant of a LOV1 domain by electron paramagnetic resonance. (2003) (46)
- Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers. (2015) (46)
- Unifying photocycle model for light adaptation and temporal evolution of cation conductance in channelrhodopsin-2 (2018) (44)
- The chromoprotein of halorhodopsin is the light-driven electrogenic chloride pump in halobacterium halobiumt. (1984) (44)
- Unfolding of the C-Terminal Jα Helix in the LOV2 Photoreceptor Domain Observed by Time-Resolved Vibrational Spectroscopy. (2016) (44)
- Structure of the retinal chromophore in halorhodopsin (1985) (44)
- Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain (2018) (43)
- Absorption and emission spectroscopic characterization of blue-light receptor Slr1694 from Synechocystis sp. PCC6803. (2007) (42)
- Hydrogen Bond Switching among Flavin and Amino Acids Determines the Nature of Proton-Coupled Electron Transfer in BLUF Photoreceptors (2012) (42)
- Reaction dynamics of the chimeric channelrhodopsin C1C2 (2017) (41)
- Probing visual transduction in a plant cell: Optical recording of rhodopsin-induced structural changes from Chlamydomonas reinhardtii. (1990) (41)
- Sensory Photoreceptors and Light Control of Flagellar Activity (2009) (40)
- MerMAIDs: a family of metagenomically discovered marine anion-conducting and intensely desensitizing channelrhodopsins (2019) (38)
- BiPOLES is an optogenetic tool developed for bidirectional dual-color control of neurons (2021) (38)
- Gloeobacter rhodopsin, limitation of proton pumping at high electrochemical load. (2013) (38)
- SINGLE PHOTONS ARE SUFFICIENT TO TRIGGER MOVEMENT RESPONSES IN Chlamydomonas reinhardtii (1988) (35)
- Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools (2014) (35)
- Picosecond events in the photochemical cycle of the light-driven chloride-pump halorhodopsin. (1985) (35)
- Spectroscopic Characterization of Flavin Mononucleotide Bound to the LOV1 Domain of Phot1 from Chlamydomonas reinhardtii ¶ (2002) (34)
- The transport activity of the light-driven chloride pump halorhodopsin is regulated by green and blue light (1985) (34)
- Photophobic responses and phototaxis in Chlamydomonas are triggered by a single rhodopsin photoreceptor (1994) (34)
- An Efficient Visual Screen for CRISPR/Cas9 Activity in Arabidopsis thaliana (2017) (33)
- Optogenetic Modulation of an Adenylate Cyclase in Toxoplasma gondii Demonstrates a Requirement of the Parasite cAMP for Host-Cell Invasion and Stage Differentiation* (2013) (33)
- The photochemistry of the light-, oxygen-, and voltage-sensitive domains in the algal blue light receptor phot. (2006) (32)
- NeoR, a near-infrared absorbing rhodopsin (2020) (32)
- The nature of rhodopsin-triggered photocurrents in Chlamydomonas. II. Influence of monovalent ions. (1996) (32)
- Quantitative Study for Oxygen Reduction and Evolution in Aprotic Organic Electrolytes at Gas Diffusion Electrodes by DEMS (2015) (31)
- Active site structure and absorption spectrum of channelrhodopsin-2 wild-type and C128T mutant (2016) (31)
- Enzymerhodopsins: novel photoregulated catalysts for optogenetics. (2019) (31)
- Single photon detection by an archaebacterium. (1988) (31)
- Color tuning in binding pocket models of the chlamydomonas-type channelrhodopsins. (2011) (30)
- Desensitization and Dark Recovery of the Photoreceptor Current in Chlamydomonas reinhardtii (1997) (30)
- Key residues for the light regulation of the blue light-activated adenylyl cyclase from Beggiatoa sp. (2014) (30)
- Hindered rotation of a cofactor methyl group as a probe for protein-cofactor interaction. (2010) (29)
- Photo dynamics of BLUF domain mutant H44R of AppA from Rhodobacter sphaeroides (2007) (29)
- Electrical properties, substrate specificity and optogenetic potential of the engineered light-driven sodium pump eKR2 (2018) (29)
- THE ROLE OF CALCIUM IN Chlamydomonas PHOTOMOVEMENT RESPONSES AS ANALYSED BY CALCIUM CHANNEL INHIBITORS (1990) (29)
- Absorption and emission spectroscopic characterisation of the LOV2-domain of phot from Chlamydomonas reinhardtii fused to a maltose binding protein (2004) (28)
- Optogenetic approaches addressing extracellular modulation of neural excitability (2016) (28)
- Lateral Gene Transfer of Anion-Conducting Channelrhodopsins between Green Algae and Giant Viruses (2020) (28)
- The hydrogen-bond switch reaction of the Blrb Bluf domain of Rhodobacter sphaeroides. (2011) (27)
- Upgrading a microplate reader for photobiology and all-optical experiments. (2015) (27)
- Time-resolved infrared spectroscopic techniques as applied to channelrhodopsin (2015) (26)
- Molecular determinants of proton selectivity and gating in the red-light activated channelrhodopsin Chrimson (2017) (25)
- Absorption and emission spectroscopic characterisation of the LOV2-His domain of phot from Chlamydomonas reinhardtii (2005) (25)
- Conversion of a light-driven proton pump into a light-gated ion channel (2015) (24)
- Covalent immobilization of oligonucleotides on electrodes (2003) (24)
- Phot-LOV 1 : Photocycle of a BlueLight Receptor Domain from the Green Alga Chlamydomonas reinhardtii (2003) (24)
- Photoadduct Formation from the FMN Singlet Excited State in the LOV2 Domain of Chlamydomonas reinhardtii Phototropin. (2016) (24)
- Photo-dynamics of the BLUF domain containing soluble adenylate cyclase (nPAC) from the amoeboflagellate Naegleria gruberi NEG-M strain (2011) (24)
- Redox Properties of LOV Domains: Chemical versus Photochemical Reduction, and Influence on the Photocycle (2007) (23)
- Photo-reduction of flavin mononucleotide to semiquinone form in LOV domain mutants of blue-light receptor phot from Chlamydomonas reinhardtii. (2007) (23)
- Heterogeneity of the Transmembrane Protein Conformation in Purple Membranes Identified by Infrared Nanospectroscopy. (2017) (23)
- Opsin evolution: out of wild green yonder? (2000) (22)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin (2021) (22)
- Photopysical and photochemical excitation and relaxation dynamics of LOV domains of phot from Chlamydomonas reinhardtii (2005) (22)
- The chromophore structure of the long‐lived intermediate of the C128T channelrhodopsin‐2 variant (2011) (22)
- Tip-Enhanced Infrared Difference-Nanospectroscopy of the Proton Pump Activity of Bacteriorhodopsin in Single Purple Membrane Patches (2019) (21)
- Optogenetics for light control of biological systems (2022) (21)
- Channelrhodopsin-1 Phosphorylation Changes with Phototactic Behavior and Responds to Physiological Stimuli in Chlamydomonas (2019) (21)
- Fast, repetitive light-activation of CaV3.2 using Channelrhodopsin 2 (2010) (20)
- Engineered Passive Potassium Conductance in the KR2 Sodium Pump. (2019) (19)
- Crystal structure of the red light-activated channelrhodopsin Chrimson (2018) (18)
- Bistable Retinal Schiff Base Photodynamics of Histidine Kinase Rhodopsin HKR1 from Chlamydomonas reinhardtii (2014) (18)
- Photophysical characterisation and photo-cycle dynamics of LOV1-His domain of phototropin from Chlamydomonas reinhardtii with roseoflavin monophosphate cofactor. (2010) (18)
- Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin (2019) (18)
- Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins. (2017) (18)
- The two parallel photocycles of the Chlamydomonas sensory photoreceptor histidine kinase rhodopsin 1. (2017) (18)
- A Set of Engineered Escherichia coli Expression Strains for Selective Isotope and Reactivity Labeling of Amino Acid Side Chains and Flavin Cofactors (2013) (17)
- Isolation and characterization of the retinal‐binding component of halorhodopsin (1982) (16)
- Rhodopsin-related proteins, Cop1, Cop2 and Chop1, in chlamydomonas reinhardtii (2003) (16)
- Photoreception in Chlamydomonas (1991) (16)
- The halo‐opsin gene. I. Identification and isolation (1987) (15)
- Dual Photoisomerization on Distinct Potential Energy Surfaces in a UV-Absorbing Rhodopsin (2020) (15)
- Absorption and emission spectroscopic characterization of BLUF protein Slr1694 from Synechocystis sp. PCC6803 with roseoflavin cofactor. (2009) (15)
- Adaptation of Chlamydomonas phototaxis: I. A light‐scattering apparatus for measuring the phototactic rate of microorganisms with high time resolution (1990) (15)
- Photo-dynamics and thermal behavior of the BLUF domain containing adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain (2013) (14)
- Thermal protein unfolding in photo-activated adenylate cyclase nano-clusters from the amoeboflagellate Naegleria gruberi NEG-M strain (2011) (14)
- Complex Photochemistry within the Green-Absorbing Channelrhodopsin ReaChR. (2017) (14)
- Biotechnology: Programming genomes with light (2013) (14)
- Mechanistic insights in light-induced cAMP production by photoactivated adenylyl cyclase alpha (PACα) (2009) (14)
- Yield of photo-adduct formation of LOV domains from Chlamydomonas reinhardtii by picosecond laser excitation (2005) (13)
- Light‐generated Paramagnetic Intermediates in BLUF Domains † (2011) (13)
- Photochemical chromophore isomerization in histidine kinase rhodopsin HKR1 (2015) (12)
- Streptomyces rimosus Aminoglycoside 3"-Phosphotransferase VIII: Comparisons with Aminoglycoside 3"-Phosphotransferases of Aminoglycoside-Producing Strains and with Eukaryotic Protein Kinases (2004) (12)
- Dynamics of voltage profile in enzymatic ion transporters, demonstrated in electrokinetics of proton pumping rhodopsin. (2008) (12)
- Absorption and fluorescence characteristics of photo-activated adenylate cyclase nano-clusters from the amoeboflagellate Naegleria gruberi NEG-M strain (2012) (11)
- Light-Induced Rearrangement of the β5 Strand in the BLUF Photoreceptor SyPixD (Slr1694). (2015) (11)
- Absorption and emission spectroscopic characterisation of 8-amino-riboflavin (2009) (10)
- Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (10)
- Concept for a single-shot mid-infrared spectrometer using synchrotron radiation (2014) (10)
- Photo-dynamics of BLUF domain containing adenylyl cyclase NgPAC3 from the amoeboflagellate Naegleria gruberi NEG-M strain (2014) (10)
- Collective exchange processes reveal an active site proton cage in bacteriorhodopsin (2020) (10)
- Absorption and emission spectroscopic characterization of photo-dynamics of photoactivated adenylyl cyclase mutant bPAC-Y7F of Beggiatoa sp. (2014) (9)
- Proton transfer reactions in the red light-activatable channelrhodopsin variant ReaChR and their relevance for its function (2017) (9)
- Photocycle Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor QuasAr1 (2019) (8)
- Gene Editing in Green Alga Chlamydomonas reinhardtii via CRISPR-Cas9 Ribonucleoproteins. (2022) (8)
- Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels (2022) (8)
- Towards an identification of chemically different flavin radicals by means of theirg-tensor (2006) (8)
- BiPOLES: a tool for bidirectional dual-color optogenetic control of neurons (2020) (8)
- The femtosecond-to-second photochemistry of red-shifted fast-closing anion channelrhodopsin PsACR1. (2017) (8)
- Trans-cis isomerization of retinal and a mechanism for ion translocation in halorhodopsin (1986) (8)
- Absorption and Emission Spectroscopic Investigation of the Thermal Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor QuasAr1 (2019) (7)
- Féry IR Spectrometer for Single-Shot Analysis of Protein Dynamics. (2019) (7)
- Photocycle dynamics of the Archaerhodopsin 3 based fluorescent voltage sensor Archon2. (2021) (7)
- QuasAr Odyssey: the origin of fluorescence and its voltage sensitivity in microbial rhodopsins (2022) (7)
- Reconstitution of halorhodopsin in black lipid membranes. (1984) (7)
- Modeling Light-induced Currents in the Eye of Chlamydomonas reinhardtii (2002) (6)
- Tracking Pore Hydration in Channelrhodopsin by Site-Directed Infrared-Active Azido Probes. (2019) (6)
- Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae (2017) (6)
- Absorption and emission spectroscopic characterisation of combined wildtype LOV1-LOV2 domain of phot from Chlamydomonas reinhardtii. (2005) (6)
- Modulation of Light Energy Transfer from Chromophore to Protein in the Channelrhodopsin ReaChR. (2020) (5)
- Stability of Tetraglyme for Reversible Magnesium Deposition from a Magnesium Aluminum Chloride Complex (2019) (5)
- Phototaxis of Chlamydomonas eugametos pairs is controlled by the mt+ partner (1991) (5)
- WiChR, a highly potassium-selective channelrhodopsin for low-light one- and two-photon inhibition of excitable cells (2022) (5)
- Photo-degradation behaviour of roseoflavin in some aqueous solutions (2010) (5)
- Chlamydomonas POLQ is necessary for CRISPR/Cas9-mediated gene targeting (2021) (5)
- Photo-dynamics of the lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain (2013) (5)
- Optogenetic tools for manipulation of cyclic nucleotides functionally coupled to cyclic nucleotide‐gated channels (2021) (5)
- Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in the dark state. (2003) (5)
- Photoreceptor current and photoorientation in chlamydomonas mediated by 9-demethylchlamyrhodopsin. (2001) (4)
- E. Hochmuth, Photo-induced Degradation of some Flavines in Aqueous Solution, (2005) (4)
- Photoreactions of the Histidine Kinase Rhodopsin Ot-HKR from the Marine Picoalga Ostreococcus tauri. (2019) (4)
- Photodynamics of the optogenetic BLUF coupled photoactivated adenylyl cyclases (PACs) (2016) (4)
- The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy (2021) (4)
- Altered N-glycan composition impacts flagella mediated adhesion in Chlamydomonas reinhardtii (2020) (4)
- Corrigendum to “Quantum yield of triplet formation of riboflavin in aqueous solution and of flavin mononucleotide bound to the LOV1 domain of Phot1 from Chlamydomonas reinhardtii” [Chemical Physics 291 (2003) 97–114] (2003) (4)
- Absorption and emission spectroscopic investigation of thermal dynamics and photo-dynamics of the rhodopsin domain of the rhodopsin-guanylyl cyclase from the aquatic fungus Blastocladiella emersonii (2016) (4)
- Conformational changes of a membrane protein determined by infrared difference spectroscopy beyond the diffraction limit (2021) (3)
- Erratum: Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools (2015) (3)
- Absorption and Emission Spectroscopic Investigation of the Thermal Dynamics of the Archaerhodopsin 3 Based Fluorescent Voltage Sensor Archon2 (2020) (3)
- BIOCHEMICAL CHARACTERIZATION OF PHOTOACTIVATED ADENYLYL CYCLASE FROM NAEGLERIA GRUBERI (2014) (3)
- Molecular determinants of proton selectivity and gating in the red-light activated channelrhodopsin Chrimson (2017) (3)
- Chapter 11 – Photoreception in Chlamydomonas (1993) (2)
- Oxygen Reduction and Oxygen Evolution Reactions in Non-Aqueous Electrolyte As Studies By Dems (2014) (2)
- Optogenetic tools for manipulation of cyclic nucleotides, functionally coupled to CNG-channels (2020) (2)
- WiChR, a highly potassium selective channelrhodopsin for low-light two-photon neuronal inhibition (2022) (2)
- Tailoring Organic LEDs for Bidirectional Optogenetic Control via Dual‐Color Switching (2021) (2)
- Chapter 8 Algal eyes and their rhodopsin photoreceptors (2001) (2)
- Altered N-glycan composition impacts flagella-mediated adhesion in Chlamydomonas reinhardtii (2020) (2)
- [Identification of Rad51 protein from Chlamydomonas reinhardtii: recombinational characteristics]. (2005) (2)
- All-optical closed-loop voltage clamp for precise control of muscles and neurons in live animals (2022) (2)
- Fluorescence Quenching of Aqueous Solutions of Riboflavin by Methionin andCystein (2003) (2)
- Absorption and Emission Spectroscopic Characterisation of BLUF Domain ofAppA from Rhodobacter spheroides. (2005) (1)
- Adventure beyond borders of scientific fields with optogenetics (2013) (1)
- Author Correction: Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior (2018) (1)
- Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii (2022) (1)
- Photo-cycle dynamics of LOV1-His domain of phototropin from Chlamydomonas reinhardtii with roseoflavin monophosphate cofactor (2010) (1)
- Artificial anion-conducting channelrhodopsins with tuned spectra, modified kinetics and enhanced light sensitivity (2017) (1)
- The Microbial Opsin Family of Optogenetic Tools Citation (2011) (1)
- Optogenetic Modulation of Cardiomyocyte Excitability (2017) (1)
- A cytoplasmic protein kinase couples engagement of Chlamydomonas ciliary receptors to cAMP-dependent cellular responses. (2022) (1)
- Author response: Controlling fertilization and cAMP signaling in sperm by optogenetics (2014) (1)
- Nanospectroscopy of single purple membranes by mid-IR resonantly-enhanced mechanical photoexpansion (2017) (1)
- Inside Cover: Evolution of the Channelrhodopsin Photocycle Model (ChemPhysChem 6/2010) (2010) (1)
- Gating and ion selectivity of Channelrhodopsins are critical for photo-activated orientation of Chlamydomonas as shown by in vivo point mutation (2022) (1)
- Aion is a bistable anion-conducting channelrhodopsin that provides temporally extended and reversible neuronal silencing (2022) (1)
- Reaction dynamics of the chimeric channelrhodopsin C1C2 (2017) (1)
- Vibrational contrast imaging and nanospectroscopy of single cell membranes by mid-IR resonantly-enhanced mechanical photoexpansion (2016) (1)
- Back Cover: Early Formation of the Ion‐Conducting Pore in Channelrhodopsin‐2 (Angew. Chem. Int. Ed. 16/2015) (2015) (0)
- Multicolor optogenetics (2011) (0)
- Tracking Pore Hydration within the Red-Activatable Channelrhodopsin ReaChR by Site-Directed Labeling with Infrared-Active Azido Probes (2017) (0)
- The photochemistry of novel flavin-binding photoreceptors (2006) (0)
- Vibrational Contrast Imaging of Membrane Proteins by Tip-enhanced Absorption in the Mid-infrared (2015) (0)
- Photoactivated cyclases: In memoriam Masakatsu Watanabe. (2015) (0)
- Site-Specific Tagging of Channelrhodopsins with Genetically-Encoded Azido Groups (2014) (0)
- SUMOylome Modulates Intraflagellar Transport Machinery and Eukaryotic Cilia Motility (2021) (0)
- Functional Studies of Volvox Channelrhodopsin Chimeras (2010) (0)
- Leading Edge Primer The Microbial Opsin Family of Optogenetic Tools (2011) (0)
- New Concepts for Presynaptic Optogenetics (2014) (0)
- From channel rhodopsins to optogenetics (2017) (0)
- Thephotocycle ofthechloride pump halorhodopsin. I:Azide- catalyzed deprotonation ofthechromophore isa sidereaction ofphotocycle intermediates inactivating thepump (1985) (0)
- Yellow Optogenetics with Volvox Channelrhodopsin Variants (2012) (0)
- Calcium-permeable channelrhodopsins for the photocontrol of calcium signalling (2022) (0)
- Channelrhodopsin: Ideas about Gating and Ion Transport (2012) (0)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: 250 microsecond structure (0)
- by Ultraviolet and Blue Light A Photochromic Histidine Kinase Rhodopsin (HKR1) That Is Bimodally Switched (2015) (0)
- Spectroscopic Investigation of the Protonpump CsR and its Leaky Derivatives (2017) (0)
- Electrical properties, substrate specificity and optogenetic potential of the engineered light-driven sodium pump eKR2 (2018) (0)
- Rhodopsin Serves as the Photoreceptor for Photomovement Responses (1991) (0)
- Author response: Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin (2021) (0)
- Light-induced conformational changes of protein receptors probed by difference mid-IR microspectroscopy (2018) (0)
- Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior (2017) (0)
- Channelrhodopsin-2 Variants with Accelerated and Decelerated Channel Kinetics (2010) (0)
- Gaining control over membrane potential by light using Channelrhodopsin (2009) (0)
- Ultrafast Laser Energy Density and Retinal Absorption Cross-Section Determination by Saturable Absorption Measurements (2014) (0)
- TheRoleofKeyAminoAcidsinthePhotoactivationPathwayoftheSynechocystisSlr1694 BLUF Domain (2009) (0)
- Spectroscopic and Computational Observation of Glutamine Tautomerization in the Blue Light Sensing Using Flavin Domain Photoreaction (2023) (0)
- Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications (2017) (0)
- Correction (2013) (0)
- Picosecond measurements on halorhodopsin of halobacterium halobium (A) (1984) (0)
- Introduction to the Symposium‐in Print: Blue light effects (2011) (0)
- Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in illuminated state. Data set of a single crystal. (2003) (0)
- crystal structure of the catalytic core of a rhodopsin-guanylyl cyclase with converted specificity in complex with ATPalphaS (2018) (0)
- Lysine acetylation regulates moonlighting activity of the E2 subunit of the chloroplast pyruvate dehydrogenase complex in Chlamydomonas. (2022) (0)
- Light-regulated adsorption and desorption of Chlamydomonas cells at surfaces. (2022) (0)
- Comparison of the Two Retinal Proteins Bacteriorhodopsin and Halorhodopsin (1986) (0)
- The Diversity of Light-Driven Ion Pumps and their Conversion into Ion Channels (2016) (0)
- Photoactivation and signal transduction of Blue Light sensors Using FAD (BLUF) (2015) (0)
- Molecular characterization of phototropin signalosome regulating photophysiological processes in green algae. (2023) (0)
- Light-Activated Cyclic Nucleotide Phosphodiesterases (2017) (0)
- Temporally extended and reversible neuronal silencing with Aion (2022) (0)
- Mutations in Cys 128 cause extreme decelerations of the Channelrhodopsin-2 kinetics (2009) (0)
- Color Shifted Channelrhodopsins- Towards Red Light Optogenetics (2010) (0)
- Color Change in Channelrhodopsin Chimera by a Single Amino Acid Replacement (2008) (0)
- Reaction Dynamics in the Chrimson Channelrhodopsin: Observation of Product-State Evolution and Slow Diffusive Protein Motions (2023) (0)
- Potassium Channel-Based Two Component Optogenetic Tool for Silencing of Excitable Cells (2018) (0)
- photoreceptor Hydrogen-bond switching through a radical pair mechanism in a flavin-binding (2006) (0)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: 50 microsecond structure (0)
- The inner mechanics of Rhodopsin (0)
- Dieter Oesterhelt (1940–2022): Life with light and color, pioneer of membrane protein research (2023) (0)
- Use of biological photoreceptor as ion channels directly controlled by light. (2003) (0)
- Author response: Altered N-glycan composition impacts flagella-mediated adhesion in Chlamydomonas reinhardtii (2020) (0)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: Dark state structure (2021) (0)
- MerMAIDs: A novel family of metagenomically discovered, marine, anion-conducting and 2 intensely desensitizing channelrhodopsins. (2019) (0)
- List of Contributors to Volume 3 (2021) (0)
- Author Correction: QuasAr Odyssey: the origin of fluorescence and its voltage sensitivity in microbial rhodopsins (2022) (0)
- HOME NEWS NOTICES PRODUCTS BUYERS GUIDE JOBS EMPLOYERS EVENTS PUBLICATIONSADVERTISE (2019) (0)
- Use of biological photoreceptor as a directly light-controlled ion channels (2003) (0)
- Difference mid-IR nanospectroscopy on individual patches of purple membranes: the proton pump activity of bacteriorhodopsin at the nanoscale (2019) (0)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: 1 microsecond structure (0)
- Author response: The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy (2021) (0)
- 1PT128 Crystal Structure of a light-gated cation channel, channeirhodopsin(The 50th Annual Meeting of the Biophysical Society of Japan) (2012) (0)
- Color-tuned Channelrhodopsins for Multiwavelength Optogenetics □ S (2020) (0)
- Limitation of Light Driven Proton Pumps at High Electrochemical Load (2014) (0)
- Light-induced conformational changes of two different Channelrhodopsin mutants probed by difference mid-Infrared microspectroscopy with Synchrotron radiation (2020) (0)
- The light activation mechanism of a novel blue-light photoreceptor (2007) (0)
- Calredoxin regulates the chloroplast NADPH-dependent thioredoxin reductase in Chlamydomonas reinhardtii (2022) (0)
- Two Hundredth Anniversary of Humboldt – University, time for new cooperations with old friends (2010) (0)
- Collective exchange processes reveal an active site proton cage in bacteriorhodopsin (2020) (0)
- Engineering photoswitchable ion channel (2011) (0)
- Optical Control of cGMP Signaling (2017) (0)
- A non-essential tryptophan residue reports structural changes of the protein backbone in a blue light photoreceptor (2015) (0)
- Intermediates of the Channel Rhodopsin Photocycle (2012) (0)
- Molecular Determinants of Photocurrent Kinetics of the Red Light Activable Channelrhodopsin Chrimson (2017) (0)
- Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling (2013) (0)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: 4 ms structure (0)
- Crystal structure of the Phot-LOV1 domain from Chlamydomonas reinhardtii in illuminated state. Composite data set. (2003) (0)
- Potassium channel-based optogenetic silencing (2018) (0)
- Artificial Anion Conducting Channelrhodopsins with Tuned Spectra, Modified Kinetics and Enhanced Light Sensitivity (2017) (0)
- Understanding the voltage-sensitivity of Arch3-based microbial rhodopsins. (2023) (0)
- A cytoplasmic protein kinase in Chlamydomonas couples engagement of ciliary receptors to rapid cellular responses (2021) (0)
- Time-resolved serial femtosecond crystallography reveals early structural changes in channelrhodopsin: 1 ms structure (0)
- Optogenetics for light control of biological systems (2022) (0)
- Author Correction: Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior (2018) (0)
- Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain (2018) (0)
- A synchrotron-based single-shot spectrometer for mid-infrared measurements (2017) (0)
- Electrophysiology of the engineered light-driven sodium pump eKR2 and its conversion into a channel (2018) (0)
- Electrophysiological Investigation of the Sodium Pump KR2 (2017) (0)
- Channelrhodopsin variants and new microbial photoreceptors for optogenetic application (2011) (0)
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