Salvador Moncada | Academic Influence

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Salvador Moncada

Medical

#31

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#57

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Pharmacology

#3

World Rank

#4

Historical Rank

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Salvador Moncada's Degrees

Doctorate Medicine University of El Salvador

Why Is Salvador Moncada Influential?

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According to Wikipedia, Sir Salvador Enrique Moncada Seidner, FRS, FRCP, FMedSci is a Honduran pharmacologist and professor. He is currently Research Domain Director for Cancer at the University of Manchester. In the past, he was the Research Director of the Wellcome Research Laboratories from 1986 to 1995 and, until recently, the Director of the UCL Wolfson Institute, which he established at University College London in 1996. His research interests include inflammation and vascular biology and he is currently working on the regulation of cell proliferation. He gained fame for his discoveries related to nitric oxide function and metabolism, and his exclusion from the 1996 Lasker Award and the 1998 Nobel Prize in medicine.

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Salvador Moncada's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Nitric oxide: physiology, pathophysiology, and pharmacology. (1991) (16074)
Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor (1987) (10739)
Vascular endothelial cells synthesize nitric oxide from L-arginine (1988) (4863)
The L-arginine-nitric oxide pathway. (1993) (4797)
An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation (1976) (3173)
Nitric oxide synthases in mammals. (1994) (2787)
Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor (1986) (2461)
Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure (1992) (2163)
Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo (1990) (1946)
Role of endothelium-derived nitric oxide in the regulation of blood pressure. (1989) (1800)
EFFECTS OF ENDOTHELIUM-DERIVED NITRIC OXIDE ON PERIPHERAL ARTERIOLAR TONE IN MAN (1989) (1676)
EICOSAPENTAENOIC ACID AND PREVENTION OF THROMBOSIS AND ATHEROSCLEROSIS? (1978) (1668)
Pharmacology and endogenous roles of prostaglandin endoperoxides, thromboxane A2, and prostacyclin. (1978) (1656)
ENDOGENOUS NITRIC OXIDE INHIBITS HUMAN PLATELET ADHESION TO VASCULAR ENDOTHELIUM (1987) (1494)
Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase. (1989) (1420)
L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. (1988) (1407)
Altered immune responses in mice lacking inducible nitric oxide synthase (1995) (1380)
Biosynthesis of nitric oxide from L-arginine. A pathway for the regulation of cell function and communication. (1989) (1257)
Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide (1994) (1235)
An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. (1990) (1226)
Mitochondrial Biogenesis in Mammals: The Role of Endogenous Nitric Oxide (2003) (1203)
The anti‐aggregating properties of vascular endothelium: interactions between prostacyclin and nitric oxide (1987) (1177)
Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. (1979) (1160)
Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. (1990) (1128)
Induction of calcium-dependent nitric oxide synthases by sex hormones. (1994) (1101)
Calorie Restriction Promotes Mitochondrial Biogenesis by Inducing the Expression of eNOS (2005) (1077)
Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides. (1976) (997)
Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans. (1991) (973)
Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac ateries and inhibits platelet aggregation. (1976) (949)
A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation (1989) (920)
NMDA receptor activation induces nitric oxide synthesis from arginine in rat brain slices. (1989) (901)
Indomethacin and aspirin abolish prostaglandin release from the spleen. (1971) (900)
HUMAN ARTERIAL AND VENOUS TISSUES GENERATE PROSTACYCLIN (PROSTAGLANDIN X), A POTENT INHIBITOR OF PLATELET AGGREGATION (1977) (892)
Comparative pharmacology of endothelium‐derived relaxing factor, nitric oxide and prostacyclin in platelets (1987) (834)
Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. (1998) (834)
Roles of nitric oxide in tumor growth. (1995) (802)
Molecular mechanisms and therapeutic strategies related to nitric oxide (1995) (790)
Does nitric oxide modulate mitochondrial energy generation and apoptosis? (2002) (784)
The discovery of nitric oxide and its role in vascular biology (2006) (781)
Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine. (1990) (768)
The role of nitric oxide and cGMP in platelet adhesion to vascular endothelium. (1987) (764)
Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases. (1992) (737)
Endogenous nitric oxide: physiology, pathology and clinical relevance (1991) (718)
Redistribution of Intracellular Oxygen in Hypoxia by Nitric Oxide: Effect on HIF1α (2003) (711)
Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide. (1992) (694)
The chemical structure of prostaglandin X (prostacyclin). (1976) (689)
Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium. (1977) (689)
Endothelium-derived relaxing factor. Identification as nitric oxide and role in the control of vascular tone and platelet function. (1988) (679)
Induction and potential biological relevance of a Ca2+‐independent nitric oxide synthase in the myocardium (1992) (661)
The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1 (2009) (659)
Hyperdynamic circulation in cirrhosis: a role for nitric oxide? (1991) (652)
Widespread tissue distribution, species distribution and changes in activity of Ca2+‐dependent and Ca2+‐independent nitric oxide synthases (1991) (651)
Nitric oxide synthase activity in human breast cancer. (1995) (640)
Protective and pathological roles of nitric oxide in endotoxin shock. (1992) (617)
The 1991 Ulf von Euler Lecture. The L-arginine: nitric oxide pathway. (1992) (614)
Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone: an insight into endotoxin shock. (1990) (614)
Inhibition of nitric oxide synthase as a potential therapeutic target. (1999) (600)
Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets. (1977) (595)
A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation. (1976) (594)
A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells. (1989) (593)
Synthesis of nitric oxide from L-arginine by neutrophils. Release and interaction with superoxide anion. (1989) (557)
Modulation of acute inflammation by endogenous nitric oxide. (1992) (552)
An Enzyme Isolated from Arteries Transforms Prostaglandin Endoperoxides to an Unstable Substance that Inhibits Platelet Aggregation. (1977) (548)
Effects of a nitric oxide synthase inhibitor in humans with septic shock. (1994) (547)
Nitric oxide, cell bioenergetics and neurodegeneration (2006) (544)
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides (1976) (517)
The Discovery of Nitric Oxide as the Endogenous Nitrovasodilator (1988) (514)
Development and mechanism of a specific supersensitivity to nitrovasodilators after inhibition of vascular nitric oxide synthesis in vivo. (1991) (508)
Role of leukocytes in acute myocardial infarction in anesthetized dogs: relationship to myocardial salvage by anti-inflammatory drugs. (1984) (508)
Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals. (2004) (495)
cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase. (1996) (479)
Endogenous Dimethylarginine as an Inhibitor of Nitric Oxide Synthesis (1992) (471)
Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat (1990) (470)
Nitric oxide synthase activity in ulcerative colitis and Crohn's disease (1993) (469)
Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. (1990) (458)
Control of regional blood flow by endothelium-derived nitric oxide. (1990) (455)
Unstable metabolites of arachidonic acid and their role in haemostasis and thrombosis. (1978) (448)
Nitric oxide synthase activity in human gynecological cancer. (1994) (443)
The simultaneous generation of superoxide and nitric oxide can initiate lipid peroxidation in human low density lipoprotein. (1992) (443)
Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway (2004) (425)
Inhibition of nitric oxide synthesis in septic shock: how much is beneficial? (1991) (418)
Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat. (1990) (411)
Feedback inhibition of nitric oxide synthase activity by nitric oxide (1993) (409)
Differential induction of brain, lung and liver nitric oxide synthase by endotoxin in the rat. (1990) (401)
Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies (2002) (398)
Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa (1980) (397)
Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-gamma in murine macrophages. (1992) (395)
The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death. (2000) (393)
The role of TH1 and TH2 cells in a rodent malaria infection. (1993) (391)
Different responses of astrocytes and neurons to nitric oxide: The role of glycolytically generated ATP in astrocyte protection (2001) (390)
Effect of local intra-arterial NG-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal. (1992) (389)
DIPYRIDAMOLE AND OTHER PHOSPHODIESTERASE INHIBITORS ACT AS ANTITHROMBOTIC AGENTS BY POTENTIATING ENDOGENOUS PROSTACYCLIN (1978) (385)
Prostacyclin (PGX) is the endogeneous metabolite responsible for relaxation of coronary arteries induced by arachidonic acid (1977) (381)
Prostacyclin is a circulating hormone (1978) (381)
International Union of Pharmacology Nomenclature in Nitric Oxide Research. (1997) (377)
Localization of nitric oxide synthase in the adult rat brain. (1994) (375)
Nitric oxide synthase activities in human myocardium (1993) (366)
Paradoxical fate and biological action of peroxynitrite on human platelets. (1994) (363)
Mitochondria as signaling organelles in the vascular endothelium. (2006) (359)
Nitric oxide and the vascular endothelium. (2006) (356)
Nitric Oxide Functions as an Inhibitor of Platelet Adhesion Under Flow Conditions (1992) (348)
Nitric Oxide in the Vasculature: Physiology and Pathophysiology (1997) (344)
Comparison of the effects of prostacyclin (PGI2), prostaglandin E1 and D2 on platelet aggregation in different species. (1978) (337)
S‐nitroso‐glutathione inhibits platelet activation in vitro and in vivo (1992) (334)
Nitric oxide: discovery and impact on clinical medicine (1999) (333)
Modulation of adjuvant arthritis by endogenous nitric oxide (1993) (330)
Characterization of the l‐arginine: nitric oxide pathway in human platelets (1990) (329)
Biphasic Regulation of NF-κB Activity Underlies the Pro- and Anti-Inflammatory Actions of Nitric Oxide1 (2001) (327)
Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose. (1996) (324)
NITRIC OXIDE PHYSIOLOGY (1997) (320)
Prostaglandins, Aspirin-like Drugs and the Oedema of Inflammation (1973) (317)
Glycolysis: a bioenergetic or a survival pathway? (2010) (315)
TNF-alpha downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents. (2006) (315)
Nitric oxide and mitochondrial signaling: from physiology to pathophysiology. (2007) (314)
On the mechanism by which vascular endothelial cells regulate their oxygen consumption. (1999) (314)
Prostaglandins and the mechanism of analgesia produced by aspirin‐like drugs (1997) (311)
The L-arginine:nitric oxide pathway is the major source of plasma nitrite in fasted humans. (1995) (308)
Cloning, characterization, and expression of a cDNA encoding an inducible nitric oxide synthase from the human chondrocyte. (1993) (307)
The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat (1993) (305)
Nitric oxide synthesized from L‐arginine regulates vascular tone in the coronary circulation of the rabbit (1989) (305)
The role of prostacyclin in vascular tissue. (1979) (304)
Patients with achalasia lack nitric oxide synthase in the gastro‐oesophageal junction (1993) (303)
Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. (1994) (301)
Imidazole: a selective inhibitor of thromboxane synthetase. (1977) (301)
Nitric oxide as a signal in blood vessels. (1992) (294)
Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes. (1978) (292)
Role of endothelium-derived relaxing factor in regulation of renal hemodynamic responses. (1990) (290)
Induction of nitric oxide synthase in human chondrocytes. (1993) (285)
Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major (1994) (282)
Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline. (1991) (282)
COMPARISON OF THE VASODEPRESSOR EFFECTS OF PROSTACYCLIN AND 6‐OXO‐PROSTAGLANDIN F1α WITH THOSE OF PROSTAGLANDIN E2 IN RATS AND RABBITS (1978) (278)
Effects of NG-nitro-L-arginine methyl ester on renal function and blood pressure. (1991) (278)
The prostacyclin--thromboxane A2 balance: pathophysiological and therapeutic implications. (1983) (275)
Nitric oxide inhibits mitochondrial NADH:ubiquinone reductase activity through peroxynitrite formation. (2001) (273)
The killing of Leishmania major by human macrophages is mediated by nitric oxide induced after ligation of the Fc epsilon RII/CD23 surface antigen. (1995) (273)
Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition. (1992) (266)
EIGHTH GADDUM MEMORIAL LECTURE UNIVERSITY OF LONDON INSTITUTE OF EDUCATION DECEMBER 1980: BIOLOGICAL IMPORTANCE OF PROSTACYCLIN (1982) (264)
Peroxynitrite modification of low‐density lipoprotein leads to recognition by the macrophage scavenger receptor (1993) (262)
Identification of N‐iminoethyl‐l‐ornithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells (1991) (258)
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production (2007) (256)
Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries (1990) (256)
Regulation of hypoxia-inducible factor-1alpha by nitric oxide through mitochondria-dependent and -independent pathways. (2003) (254)
The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammation. (1980) (251)
Nitric oxide from L-arginine stimulates the soluble guanylate cyclase in adrenal glands. (1989) (250)
The role of nitric oxide in endothelial cell damage and its inhibition by glucocorticoids (1992) (247)
Bioassay of prostacyclin and endothelium‐derived relaxing factor (EDRF) from porcine aortic endothelial cells (1997) (243)
L-arginine transport is increased in macrophages generating nitric oxide. (1992) (243)
Effects of inhibiting nitric oxide biosynthesis on the systemic and splanchnic circulation of rats with portal hypertension (1992) (242)
A possible novel pathway of regulation by murine T helper type‐2 (Th2) cells of a Th1 cell activity via the modulation of the induction of nitric oxide synthase on macrophages (1991) (240)
Defective Mitochondrial Biogenesis: A Hallmark of the High Cardiovascular Risk in the Metabolic Syndrome? (2007) (234)
Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo (2005) (234)
Platelet adhesion to human vascular endothelium is modulated by constitutive and cytokine induced nitric oxide. (1993) (233)
Rapid development of atherosclerotic lesions in the rabbit carotid artery induced by perivascular manipulation. (1989) (231)
Understanding the controversy over the identity of EDRF (1994) (230)
Regulation of Vascular Homeostasis by Nitric Oxide (1993) (229)
Resistance to Leishmania major infection correlates with the induction of nitric oxide synthase in murine macrophages (1991) (228)
Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint. (1975) (228)
The role of nitric oxide in cardiac depression induced by interleukin‐1β and tumour necrosis factor‐α (1995) (219)
Arrest of preterm labour and prolongation of gestation with glyceryl trinitrate, a nitric oxide donor (1994) (219)
Inhibition of platelet activity by S-nitrosoglutathione during coronary angioplasty (1994) (219)
Endogenous nitric oxide as a probable modulator of pulmonary circulation and hypoxic pressor response in vivo. (1990) (216)
Inducible nitric oxide synthase is increased in murine lung epithelial cells by cytokine stimulation. (1994) (213)
Mechanism of action of some inhibitors of endothelium-derived relaxing factor. (1986) (212)
The actions of nitric oxide donors in the prevention or induction of injury to the rat gastric mucosa (1993) (211)
Biosynthesis and biological activity of leukotriene B5. (1984) (210)
An improved method for washing of human platelets with prostacyclin. (1983) (209)
Expression of inducible nitric oxide synthase in human heart failure. (1997) (209)
Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment. (2003) (205)
L-arginine: nitric oxide pathway in endotoxemia and human septic shock. (1995) (205)
Human colorectal adenocarcinoma cells: differential nitric oxide synthesis determines their ability to aggregate platelets. (1991) (200)
Effects of inhibition of nitric oxide formation on basal vasomotion and endothelium-dependent responses of the coronary arteries in awake dogs. (1991) (200)
Differential induction of nitric oxide synthase in various organs of the mouse during endotoxaemia: role of TNF-alpha and IL-1-beta. (1994) (199)
Oxidative stress and S‐nitrosylation of proteins in cells (2000) (197)
Direct electrochemical measurement of nitric oxide released from human platelets. (1993) (196)
The formation of nitric oxide donors from peroxynitrite (1995) (195)
Nitric oxide, cytochrome C oxidase, and the cellular response to hypoxia. (2010) (190)
Identification of inhibitors of nitric oxide synthase that do not interact with the endothelial cell l‐arginine transporter (1992) (189)
A rapid and simple method for the measurement of nitrite and nitrate in plasma by high performance capillary electrophoresis. (1994) (189)
Endogenous NO regulates superoxide production at low oxygen concentrations by modifying the redox state of cytochrome c oxidase. (2004) (185)
The biology of nitric oxide (1997) (180)
Prostaglandins, their intermediates and precursors: cardiovascular actions and regulatory roles in normal and abnormal circulatory systems. (1979) (178)
Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation. (1994) (176)
Nitric oxide induces coupling of mitochondrial signalling with the endoplasmic reticulum stress response (2004) (176)
Selective nitrergic neurodegeneration in diabetes mellitus–a nitric oxide‐dependent phenomenon (1999) (174)
AMPKalpha1 regulates the antioxidant status of vascular endothelial cells. (2009) (173)
Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. (2003) (173)
Regional haemodynamic changes during oral ingestion of NG‐monomethyl‐l‐arginine or NG‐nitro‐l‐arginine methyl ester in conscious Brattleboro rats (1990) (171)
Induction of nitric oxide synthases early in pregnancy. (1994) (170)
The release of leukotriene B4 during experimental inflammation. (1983) (170)
Differential effect of nitric oxide on glutathione metabolism and mitochondrial function in astrocytes and neurones: implications for neuroprotection/neurodegeneration? (2003) (169)
Macrophage Endothelial Nitric-oxide Synthase Autoregulates Cellular Activation and Pro-inflammatory Protein Expression* (2003) (168)
Direct measurement of nitric oxide in human beings (1995) (166)
Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition. (1976) (166)
Induction of nitric oxide synthase in rat peritoneal neutrophils and its inhibition by dexamethasone (1991) (165)
E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation (2009) (165)
Nitric oxide synthase in cultured endocardial cells of the pig (1991) (164)
Prostacyclin and arterial wall biology. (1982) (163)
Bradykinin and ATP stimulate L-arginine uptake and nitric oxide release in vascular endothelial cells. (1991) (157)
Effect of prostacyclin (PGI2) on platelet adhesion to rabbit arterial subendothelium. (1978) (155)
RECIRCULATION OF PROSTACYCLIN (PGI2) IN THE DOG (1978) (155)
The biological and pharmacological role of nitric oxide in platelet function. (1993) (153)
Responses of human and baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: their relevance to cerebral arterial spasm in man. (1979) (152)
Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells (2011) (152)
Effects of all cis-5,8,11,14,17 eicosapentaenoic acid and PGH3 on platelet aggregation. (1979) (152)
Time‐dependent enhancement or inhibition of endotoxin‐induced vascular injury in rat intestine by nitric oxide synthase inhibitors (1994) (151)
Vasoconstriction with thromboxane A2 induces ulceration of the gastric mucosa (1981) (150)
Actions of prostacyclin (PGI2) and its product, 6-oxo-PGF1alpha on the rat gastric mucosa in vivo and in vitro. (1978) (150)
Modulation of platelet aggregation by an L-arginine-nitric oxide pathway. (1991) (150)
Kinetic characteristics of nitric oxide synthase from rat brain. (1990) (149)
Role of endogenous nitric oxide in septic shock. (1993) (147)
ASPIRIN: A PARADOXICAL EFFECT ON BLEEDING-TIME (1978) (145)
Therapeutic potential of nitric oxide donors in the prevention and treatment of atherosclerosis. (2005) (145)
Differential distribution of nitric oxide synthase between cell fractions isolated from the rat gastric mucosa. (1992) (145)
Glomeruli synthesize nitrite in experimental nephrotoxic nephritis. (1990) (142)
Comparative pharmacology of EDRF and nitric oxide on vascular strips. (1987) (141)
Eicosanoids in inflammation. (1984) (140)
The Role of Nitric Oxide in Endotoxic Shock: Effects of NG‐Monomethyl‐L‐Arginine (1992) (138)
Human colon cancer cell lines show a diverse pattern of nitric oxide synthase gene expression and nitric oxide generation. (1994) (136)
The effects of BW755C and other anti‐inflammatory drugs on eicosanoid concentrations and leukocyte accumulation in experimentally‐induced acute inflammation (1983) (135)
The oxidation of α‐tocopherol in human low‐density lipoprotein by the simultaneous generation of superoxide and nitric oxide (1993) (134)
Inhibition of mitochondrial respiration by endogenous nitric oxide: A critical step in Fas signaling (2002) (130)
A nitric oxide donor improves uterine artery diastolic blood flow in normal early pregnancy and in women at high risk of pre‐eclampsia (1994) (129)
Eicosapentaenoic acid as a modulator of inflammation. Effect on prostaglandin and leukotriene synthesis. (1986) (129)
Protective effect of S-nitroso-N-acetyl-penicillamine in endotoxin-induced acute intestinal damage in the rat. (1990) (129)
The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis. (1998) (128)
Mitochondrial biogenesis as a cellular signaling framework. (2004) (127)
The source of thromboxane and prostaglandins in experimental inflammation (1983) (126)
BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation: a promising neuroprotective strategy. (1999) (126)
Role of endothelium-derived relaxing factor in parasympathetic coronary vasodilation. (1992) (125)
Induction of nitric oxide synthase in colonic smooth muscle from patients with toxic megacolon. (1995) (124)
Anaphase-promoting complex/cyclosome-Cdh1 coordinates glycolysis and glutaminolysis with transition to S phase in human T lymphocytes (2010) (124)
Some effects of inhibiting endogenous prostaglandin formation on the responses of the cat spleen (1973) (124)
Synthesis of 6-keto-PGF1a by ram seminal vesicle microsomes (1977) (123)
Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids (1976) (123)
Acetylcholine induces vasodilatation in the rabbit isolated heart through the release of nitric oxide, the endogenous nitrovasodilator (1988) (122)
Inhibition of cellular respiration by endogenously produced carbon monoxide (2006) (122)
Induction of nitric oxide synthase and microvascular injury in the rat jejunum provoked by indomethacin (1995) (121)
Prostacyclin release and the modulation of some vasoactive hormones. (1980) (120)
The crucial role of physiological Ca2+ concentrations in the production of endothelial nitric oxide and the control of vascular tone (1990) (120)
Vascular actions of arachidonic acid and its metabolites in perfused mesenteric and femoral beds of the dog. (1978) (120)
Nitric oxide mediates tumor necrosis factor-α cytotoxicity in endothelial cells (1992) (119)
Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells (1982) (119)
The Effect of Prostacyclin (PGI2) on Platelet Behaviour. Thrombus Formation in Vivo and Bleeding Time (1979) (119)
Nitric oxide from inflammatory‐activated glia synergizes with hypoxia to induce neuronal death (2005) (119)
Biochemical characterization of S-nitrosohemoglobin. Mechanisms underlying synthesis, no release, and biological activity. (1999) (119)
Endogenous nitric oxide as a modulator of rabbit skeletal muscle microcirculation in vivo (1990) (118)
Involvement of endogenous nitric oxide in the regulation of rat intestinal motility in vivo. (1992) (117)
Lack of Oxygen Deactivates Mitochondrial Complex I (2009) (117)
Activated macrophages utilize glycolytic ATP to maintain mitochondrial membrane potential and prevent apoptotic cell death (2010) (116)
S-Nitrosation of Mitochondrial Complex I Depends on Its Structural Conformation* (2007) (116)
Carbacyclin--a potent stable prostacyclin analogue for the inhibition of platelet aggregation. (1980) (115)
Prostacyclin and thromboxane A2 synthesis by rabbit pulmonary artery. (1980) (114)
Prostacyclin: its biosynthesis, actions, and clinical potential. (1981) (114)
Pharmacological interactions between prostacyclin and thromboxanes. (1983) (114)
Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. (2000) (114)
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle (2011) (113)
The use of prostacyclin in the separation from plasma and washing of human platelets. (1982) (113)
Polymorphonuclear leukocytes produce thromboxane A2-like activity during phagocytosis. (1976) (113)
Synthesis of Nitric Oxide by the Haemocytes of the American Horseshoe Crab (Limulus polyphemus) (1991) (112)
Biology and therapeutic potential of prostacyclin. (1983) (111)
Nitric oxide synthesised from L-arginine mediates endothelium dependent dilatation in human veins in vivo. (1989) (110)
Diversion of prostaglandin endoperoxide metabolism by selective inhibition of thromboxane A2 biosynthesis in lung, spleen or platelets. (1977) (110)
Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells. (2003) (109)
Effect of local intra-arterial asymmetric dimethylarginine (ADMA) on the forearm arteriolar bed of healthy volunteers. (1993) (109)
Induction of nitric oxide synthase in rat immune complex glomerulonephritis. (1994) (108)
Biosynthesis of prostaglandin (PGI2) and 12L-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) by pericardium, pleura, peritoneum and aorta of the rabbit. (1979) (107)
Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting. (2003) (107)
Nitric oxide inhibition of Drp1-mediated mitochondrial fission is critical for myogenic differentiation (2010) (106)
Synergistic action of advanced glycation end products and endogenous nitric oxide leads to neuronal apoptosis in vitro: A new insight into selective nitrergic neuropathy in diabetes (2004) (106)
Effects of intravenous infusion of prostacyclin (PGI2) in man. (1980) (106)
Nitric oxide is a factor in the stabilization of hypoxia-inducible factor-1alpha in cancer: role of free radical formation. (2006) (105)
PROSTACYCLIN CAN REPLACE HEPARIN IN HÆMODIALYSIS IN DOGS (1978) (105)
The effects of prostacyclin (PGI2) on tissues which detect prostaglandins (PG'S). (1977) (105)
Association of microvascular leakage with induction of nitric oxide synthase: effects of nitric oxide synthase inhibitors in various organs. (1995) (105)
Actions of nitric oxide on the release of prostacyclin from bovine endothelial cells in culture. (1988) (103)
Receptor specificity and trigemino‐vascular inhibitory actions of a novel 5‐HT1B/1D receptor partial agonist, 311C90 (zolmitriptan) (1997) (102)
Y‐27632, an inhibitor of Rho‐kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum (2001) (102)
The salvage of ischaemic myocardium by BW755C in anaesthetised dogs. (1982) (102)
Effect of orally administered eicosapentaenoic acid (EPA) on the formation of leukotriene B4 and leukotriene B5 by rat leukocytes. (1984) (100)
Synthesis of nitric oxide in the bovine retina. (1991) (100)
Modulation of autonomic neuroeffector transmission by nitric oxide in guinea pig ileum. (1990) (98)
Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages. (2005) (97)
The modulation of IL-6 and TNF-α release by nitric oxide following stimulation of J774 cells with LPS and IFN-γ (1995) (97)
Arterial wall hypoxia following thrombosis of the vasa vasorum is an initial lesion in atherosclerosis (1991) (97)
Nitric oxide is present in exhaled breath in humans: direct GC-MS confirmation. (1994) (96)
Transformation of arachidonic acid and prostaglandin endoperoxides by the guinea pig heart. Formation of RCS and prostacyclin. (1978) (96)
Nitric oxide and the haemodynamic profile of endotoxin shock in the conscious mouse (1998) (95)
Nitric oxide gas: mediator, modulator, and pathophysiologic entity. (1992) (95)
Adventures in vascular biology: a tale of two mediators (2006) (95)
Stimulation of cyclic GMP production in cultured endothelial cells of the pig by bradykinin, adenosine diphosphate, calcium ionophore A23187 and nitric oxide (1990) (94)
Peroxynitrite and atherosclerosis. (1993) (94)
Vascular smooth muscle contains a depletable store of a vasodilator which is light-activated and restored by donors of nitric oxide. (1993) (93)
Discrepancies Between Nitroglycerin and NO-Releasing Drugs on Mitochondrial Oxygen Consumption, Vasoactivity, and the Release of NO (2005) (91)
Nitric oxide synthase is expressed in human macrophages during foreign body inflammation. (1997) (91)
Inflammatory effects of prostacyclin (PGI2) and 6-oxo-PGF1α in the rat paw (1978) (90)
PROSTACYCLIN: A SOLUTION TO SOME PROBLEMS OF EXTRACORPOREAL CIRCULATION Experiments in Greyhounds (1979) (89)
Human and rabbit cavernosal smooth muscle cells express Rho-kinase (2002) (86)
Protective effects of inhibitors of nitric oxide synthase in immune complex‐induced vasculitis (1992) (86)
GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo (2005) (85)
Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway (2016) (85)
Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt. (2003) (84)
Role of basal release of nitric oxide on coronary flow and mechanical performance of the isolated rat heart. (1992) (84)
Hormonal, renal, and metabolic alterations during hypertension induced by chronic inhibition of NO in rats. (1994) (84)
Glucocorticoids do not affect the induction of a novel calcium-dependent nitric oxide synthase in rabbit chondrocytes. (1992) (83)
Cytochrome c oxidase regulates endogenous nitric oxide availability in respiring cells: A possible explanation for hypoxic vasodilation (2007) (81)
Nitrergic control of peripheral sympathetic responses in the human corpus cavernosum: a comparison with other species. (1997) (81)
Pain and Inflammatory Mediators (1978) (81)
Endothelium-derived relaxing factor is identified as nitric oxide (1987) (80)
THE DISCOVERY OF PROSTACYCLIN – – – A FRESH INSIGHT INTO ARACHIDONIC ACID METABOLISM (1977) (79)
Nitric oxide synthase inhibitors cause sustained, but reversible, hypertension and hindquarters vasoconstriction in Brattleboro rats. (1992) (79)
Nitric oxide generation. A predictive parameter of acute allograft rejection. (1994) (78)
Relationship Between Nitric Oxide Synthesis and Increase in Systolic Blood Pressure in Women with Hypertension in Pregnancy (1993) (77)
Platelet and cardiovascular activity of the hydantoin BW245C, a potent prostaglandin analogue. (1983) (77)
Nitric oxide as a factor in inflammation (1999) (77)
The Ontogeny of Cerebral and Cerebellar Nitric Oxide Synthase in the Guinea Pig and Rat (1996) (76)
Nitrergic neurotransmission mediates the non‐adrenergic non‐cholinergic responses in the clitoral corpus cavernosum of the rabbit (1998) (74)
The biological significance of nitric oxide formation from L-arginine. (1989) (73)
Leucocyte infiltration and cartilage proteoglycan loss in immune arthritis in the rabbit (1988) (73)
Arachidonate metabolism in blood cells and the vessel wall. (1986) (72)
The role of nitric oxide in cardiac depression induced by interleukin-1 beta and tumour necrosis factor-alpha. (1995) (71)
Prostacyclin mediates the potentiated hypotensive effect of bradykinin following captopril treatment. (1980) (71)
Treatment of cutaneous leishmaniasis with nitric-oxide donor (1998) (71)
Sequential induction of nitric oxide synthase by Corynebacterium parvum in different organs of the mouse (1995) (71)
Regional and cardiac haemodynamic effects of NG, NG,dimethyl‐l‐arginne and their reversibility by vasodilators in conscious rats (1993) (69)
Phagocytosis and induction of nitric oxide synthase in murine macrophages. (1993) (68)
Induction of macrophage parasiticidal activity by Staphylococcus aureus and exotoxins through the nitric oxide synthesis pathway. (1993) (68)
Prostacyclin (PGI2) induces coronary vasodilatation in anaesthetised dogs. (1978) (68)
Inhibition of mitochondrial respiration by the anticancer agent 2-methoxyestradiol. (2004) (68)
The L-arginine: nitric oxide pathway, cellular transduction and immunological roles. (1993) (68)
Interleukin-8 inhibits the induction of nitric oxide synthase in rat peritoneal neutrophils. (1992) (68)
Inhibition of nitrergic relaxations by a selective inhibitor of the soluble guanylate cyclase (1996) (67)
Coronary vasodilatation induced by endotoxin in the rabbit isolated perfused heart is nitric oxide‐dependent and inhibited by dexamethasone (1991) (67)
Glucocorticoids inhibit the induction of nitric oxide synthase and the related cell damage in adenocarcinoma cells. (1991) (66)
Fulfilling the metabolic requirements for cell proliferation. (2012) (66)
Nitric oxide and hypoxia. (2007) (65)
Prostacyclin in the cardiovascular system. (1980) (65)
Biotransformation and cardiovascular effects of arachidonic acid in the dog. (1979) (64)
Transcellular regulation of cell respiration by nitric oxide generated by activated macrophages (1998) (64)
The mechanism of enhancement by fatty acid hydroperoxides of anaphylactic mediator release. (1978) (64)
Treatment of HELLP syndrome with nitric oxide donor (1995) (64)
Release of nitric oxide by nerve stimulation in the human urogenital tract. (1994) (63)
Regulation of Oxygen Distribution in Tissues by Endothelial Nitric Oxide (2009) (63)
Nitric oxide, a vital poison inside the immune and inflammatory network. (1995) (63)
Nitric oxide mediates rat mucosal vasodilatation induced by intragastric capsaicin. (1992) (62)
BAY41-2272, a novel nitric oxide independent soluble guanylate cyclase activator, relaxes human and rabbit corpus cavernosum in vitro. (2003) (62)
Recombinant migration inhibitory factor induces nitric oxide synthase in murine macrophages. (1993) (61)
Nitric oxide and the regulation of blood pressure in the hypertension-prone and hypertension-resistant Sabra rat. (1996) (61)
Prostacyclin (PGI2) is a weak contractor of coronary arteries of the pig. (1977) (61)
Catalase inhibits nitric oxide synthesis and the killing of intracellular Leishmania major in murine macrophages (1992) (61)
Nitric oxide: orchestrating hypoxia regulation through mitochondrial respiration and the endoplasmic reticulum stress response (2005) (61)
Prostacyclin prolongs viability of washed human platelets. (1982) (61)
Nitric oxide: from discovery to the clinic. (1998) (60)
Nitric oxide: The elusive mediator of the hyperdynamic circulation of cirrhosis? (1992) (60)
Metabolism of Arachidonic Acid (1988) (59)
Prostacyclin (PGI2) and thromboxane A2 interaction in vivo. Regulation by aspirin and relationship with anti-thrombotic therapy. (1978) (59)
Release of nitric oxide evoked by nerve stimulation in guinea-pig intestine (1993) (59)
The anaphylactic release of platelet‐activating factor from perfused guinea‐pig lungs (1986) (59)
Porcine ventricular endocardial cells in culture express the inducible form of nitric oxide synthase (1993) (59)
Reduction by prostacyclin of acetaminophen‐induced liver toxicity in the mouse (1988) (58)
The Determination of Plasma Nitrite and Nitrate by Capillary Ion Analysis (1995) (57)
Prostacyclin in physiology and pathophysiology. (1982) (56)
Mapping of the genes encoding human inducible and endothelial nitric oxide synthase (NOS2 and NOS3) to the pericentric region of chromosome 17 and to chromosome 7, respectively. (1994) (56)
Prolonged paradoxical effect of aspirin on platelet behaviour and bleeding time in man. (1979) (56)
Enhancement of anaphylactic mediator release from guinea-pig perfused lungs by fatty acid hydroperoxides. (1978) (56)
Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid. (1977) (55)
Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator, BAY 41-2272. (2003) (55)
Local opioid‐sensitive afferent sensory neurones in the modulation of gastric damage induced by Paf (1989) (55)
S-Nitrosoglutathione inhibits platelet activation and deposition in coronary artery saphenous vein grafts in vitro and in vivo (1998) (54)
Endogenous nitric oxide modulates morphine-induced constipation. (1991) (54)
Substituting Angiotensin-(1-7) to Prevent Lung Damage in SARS-CoV-2 Infection? (2020) (54)
Cytochrome c oxidase maintains mitochondrial respiration during partial inhibition by nitric oxide (2006) (54)
The arginine/nitric oxide pathway modulates sphincter of Oddi motor activity in guinea pigs and rabbits. (1993) (53)
Modulatory role of endogenous nitric oxide in pulmonary circulation in vivo. (1990) (53)
Nitric oxide synthase. Structural studies using anti-peptide antibodies. (1993) (53)
Inhibition by Lamotrigine of the Generation of Nitric Oxide in Rat Forebrain Slices (1995) (53)
Comparative pharmacology of analogues of S‐nitroso‐N‐acetyl‐dl‐penicillamine on human platelets (1994) (52)
Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock. (1992) (52)
Constitutive and inducible nitric oxide synthases in human megakaryoblastic cells. (1992) (52)
Inhibition of gastric acid secretion by stress: a protective reflex mediated by cerebral nitric oxide. (1996) (52)
Arachidonic acid metabolism as a source of inflammatory mediators and its inhibition as a mechanism of action for anti-inflammatory drugs (1981) (52)
Arterial wall hypoxia following hyperfusion through the vasa vasorum is an initial lesion in atherosclerosis (1990) (52)
Further experiments to establish that the analgesic action of aspirin-like drugs depends on the inhibition of prostaglandin biosynthesis. (1973) (51)
Localization of inducible nitric oxide synthase in acute renal allograft rejection in the rat. (1994) (51)
Bioassay of prostaglandins and biologically active substances derived from arachidonic acid. (1978) (51)
Interactions of constitutive nitric oxide with PAF and thromboxane on rat intestinal vascular integrity in acute endotoxaemia (1994) (50)
Visualisation of nitric oxide released by nerve stimulation (1997) (50)
Molecular cloning and structural organization of the human inducible nitric oxide synthase gene (NOS2). (1996) (50)
ANTITHROMBOTIC PROPERTIES OF VASCULAR ENDOTHELIUM (1977) (49)
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis (2002) (49)
PROSTACYCLIN (PGI2) INHIBITS THE FORMATION OF PLATELET THROMBI IN ARTERIOLES AND VENULES OF THE HAMSTER CHEEK POUCH (1978) (49)
The use of stable prostaglandins to investigate prostacyclin (PGI2)-binding sites and PGI2-sensitive adenylate cyclase in human platelet membranes. (1984) (49)
Role of nitric oxide synthesis in the regulation of coronary vascular tone in the isolated perfused rabbit heart. (1992) (49)
Subcellular localization of nitric oxide synthase in the cerebral ventricular system, subfornical organ, area postrema, and blood vessels of the rat brain (1997) (48)
Increased expression of arginase II in patients with different forms of arthritis. Implications of the regulation of nitric oxide. (2002) (47)
Biosynthesis and Role of the Endothelium‐Derived Vasodilator, Nitric Oxide, in the Gastric Mucosa (1992) (47)
Repeated induction of nitric oxide synthase and leishmanicidal activity in murine macrophages (1993) (47)
Nitric Oxide - From Mediator to Medicines (1994) (46)
Purification to homogeneity and characterisation of rat brain recombinant nitric oxide synthase. (1995) (46)
Monitoring cytochrome redox changes in the mitochondria of intact cells using multi-wavelength visible light spectroscopy. (2003) (46)
Characterization of the non‐nitrergic NANC relaxation responses in the rabbit vaginal wall (2002) (46)
Regulation of gall bladder motility by the arginine-nitric oxide pathway in guinea pigs. (1993) (46)
The first Robert Furchgott lecture: from endothelium-dependent relaxation to the L-arginine:NO pathway. (1990) (45)
Prostacyclin release induced by bradykinin may contribute to the antihypertensive action of angiotensin-converting enzyme inhibitors. (1980) (44)
Inhibition of the induction of nitric oxide synthase by glucocorticoids: yet another explanation for their anti-inflammatory effects? (1991) (44)
Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755C. (1984) (44)
Preparation and biochemical properties of PGH3. (1979) (43)
Does nitric oxide allow endothelial cells to sense hypoxia and mediate hypoxic vasodilatation?in vivo and in vitro studies (2003) (42)
Biosynthesis and actions of nitric oxide. (1991) (42)
Differential release of eicosanoids by bradykinin, arachidonic acid and calcium ionophore A23187 in guinea‐pig isolated perfused lung (1985) (42)
Role of nitric oxide pathway in the protection against lethal endotoxemia afforded by low doses of lipopolysaccharide. (1993) (41)
Impairment of nitrergic‐mediated relaxation of rat isolated duodenum by experimental diabetes (1995) (41)
The role of nitric oxide in mediating endothelium dependent relaxations in the human epicardial coronary artery. (1990) (41)
Continuous exposure to high concentrations of nitric oxide leads to persistent inhibition of oxygen consumption by J774 cells as well as extraction of oxygen by the extracellular medium. (2000) (41)
NCX‐4016, a nitric oxide‐releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function (2002) (40)
Cloning and expression of a rat neuronal nitric oxide synthase coding sequence in a baculovirus/insect cell system. (1993) (40)
NG-monomethyl-L-arginine does not inhibit the hindquarters vasodilator action of endothelin-1 in conscious rats. (1989) (39)
Reversible inhibition of cellular respiration by nitric oxide in vascular inflammation. (2001) (38)
Visualisation of nitric oxide generated by activated murine macrophages. (1996) (38)
Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival (2014) (38)
Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress (2007) (38)
The Effects of a Novel Series of Selective Inhibitors of Arachidonate 5‐Lipoxygenase on Anaphylactic and Inflammatory Responses (1988) (38)
Characterization of nitrergic neurotransmission during short‐and long‐term electrical stimulation of the rabbit anococcygeus muscle (1995) (37)
Nitric oxide and cell respiration: physiology and pathology. (2000) (37)
Prostaglandins and thromboxanes from fatty acids. (1986) (37)
An antiserum to 5,6-dihydro prostacyclin (PGI1) which also binds prostacyclin. (1978) (37)
VASODILATION Evolution of nitric oxide (1993) (37)
Relationship between prostacyclin and nitric oxide in the thrombotic process. (1990) (37)
Short term suppression of hyperacute renal allograft rejection in presensitised dogs with prostacyclin. (1980) (36)
Megakaryocytes from patients with coronary atherosclerosis express the inducible nitric oxide synthase. (1995) (36)
The role of induction of nitric oxide synthesis in the altered responses of jugular veins from endotoxaemic rabbits (1992) (36)
The interactions of platelet-derived mediators on isolated canine coronary arteries. (1982) (36)
Ultrastructural Findings in the Murine Nonciliated Bronchiolar Cells (NCBC) after Subacute Inhalation of Lead Acetate (1999) (35)
Chlorpromazine inhibits both the constitutive nitric oxide synthase and the induction of nitric oxide synthase after LPS challenge. (1993) (35)
Identification of the domains of neuronal nitric oxide synthase by limited proteolysis. (1996) (35)
Nitric oxide mediates tumor necrosis factor-alpha cytotoxicity in endothelial cells. (1992) (35)
Biological significance and therapeutic potential of prostacyclin. (1980) (35)
Platelet actions of stable carbocyclic analogues of prostacyclin. (1985) (35)
The modulation of IL-6 and TNF-alpha release by nitric oxide following stimulation of J774 cells with LPS and IFN-gamma. (1995) (35)
The renal haemodynamic and excretory actions of prostacyclin and 6-oxo-PGF1 alpha in anaesthetized dogs. (1979) (34)
From pollutant gas to biological messenger: the diverse actions of nitric oxide in cancer. (2002) (34)
Prostacyclin, thromboxane A2 interactions in haemostasis and thrombosis. (1979) (34)
Myometrial arginase activity increases with advancing pregnancy in the guinea pig. (1996) (34)
Proceedings: Potentiation by prostaglandins of the nociceptive activity of bradykinin in the dog knee joint. (1974) (34)
Nitric oxide (NO) synthase immunoreactivity in the starfish Marthasterias glacialis (1994) (34)
Association between biosynthesis of nitric oxide and changes in immunological and vascular parameters in patients treated with interleukin‐2 (1994) (34)
Elevated Immunoglobulin E against Recombinant Brugia malayi γ-Glutamyl Transpeptidase in Patients with Bancroftian Filariasis: Association with Tropical Pulmonary Eosinophilia or Putative Immunity (2003) (34)
Nitric oxide donors preferentially inhibit neuronally mediated rat gastric acid secretion. (1994) (34)
Prostacyclin, from discovery to clinical application. (1985) (34)
Immunological detection of nitric oxide synthase(s) in human tissues using heterologous antibodies suggesting different isoforms (1992) (33)
Prostacyclin: homeostatic regulator or biological curiosity? (1981) (33)
Effect of nitric oxide gas on the generation of nitric oxide by isolated blood vessels: implications for inhalation therapy (1994) (33)
BLOOD PRESSURE, ERYTHROPOIETIN, AND NITRIC OXIDE (1988) (33)
PROSTACYCLIN FORMATION AND EFFECTS (1979) (33)
The Problems and the Promise of Prostaglandin Influences in Atherogenesis (1985) (32)
Isolation and washing of human platelets with nitric oxide. (1988) (32)
The effects of prostagladin endoperoxides and thromboxane A2 on strips of rabbit coeliac artery and certain other smooth muscle preparations [proceedings]. (1976) (32)
Disappearance of prostacyclin (PGI2) in the circulation of the dog [proceedings]. (1978) (32)
Nitric oxide and pulmonary arterial hypertension (2017) (31)
Prostacyclin and its clinical applications. (1984) (31)
Microcirculatory effects of prostacyclin (PGI2) in the hamster cheek pouch. (1979) (30)
Nitric oxide and the pathogenesis of heart muscle disease (1995) (30)
Mitochondrial dysfunction and HIF1α stabilization in inflammation (2008) (29)
Attenuation by nitrosothiol NO donors of acute intestinal microvascular dysfunction in the rat (1995) (29)
on renal function and blood pressure (1991) (29)
Enzymatic preparation of prostaglandin endoperoxides. (1977) (29)
Hemostatic mechanisms, independent of platelet aggregation, arrest gastric mucosal bleeding. (1986) (29)
Prostacyclin (PGI2), the Vascular Wall and Vasodilatation (1978) (29)
Effects of prostacyclin on coronary circulation, heart rate and myocardial contractile force in isolated hearts of guinea pig and rabbit - comparison with prostaglandin E2. (1979) (29)
Activation of adrenal medullary L-arginine: nitric oxide pathway by stimuli which induce the release of catecholamines. (1993) (29)
The endothelin explosion. A pathophysiological reality or a biological curiosity? (1990) (28)
NITRIC OXIDE FROM INDUCIBLE NITRIC OXIDE SYNTHASE SENSITIZES THE INFLAMED AORTA TO HYPOXIC DAMAGE VIA RESPIRATORY INHIBITION (2005) (28)
Calcium supplementation prevents pregnancy-induced hypertension by increasing the production of vascular nitric oxide. (1995) (28)
Central vagal activation by an analogue of TRH stimulates gastric nitric oxide release in rats. (1995) (28)
The deleterious effect of high concentrations of D-glucose requires pro-inflammatory preconditioning (2008) (28)
Leukotriene B4 production in normal rat glomeruli. (1987) (27)
Proceedings: the concomitant release of bradykinin and prostaglandin in the inflammatory response to carrageenin. (1974) (27)
Regulation by endogenous INTERLEUKIN-10 of the expression of nitric oxide synthase induced after ligation of CD23 in human macrophages. (1998) (27)
Modulation by opioids and by afferent sensory neurones of prostanoid protection of the rat gastric mucosa (1992) (27)
Effect of a thromboxane synthetase inhibitor on eicosanoid synthesis and glomerular injury during acute unilateral glomerulonephritis in the rat. (1986) (27)
Cardiovascular actions of prostacyclin (PCI2) in chloralose anaesthetized dogs [proceedings]. (1977) (27)
Symposium on regression of atherosclerosis (1993) (27)
Unstable metabolites of arachidonic acid aspirin and the formation of the haemostatic plug. (1978) (26)
Enhancers of nonspecific immunity induce nitric oxide synthase: Induction does not correlate with toxicity or adjuvancy (1992) (26)
Release of prostaglandins and incapacitation after injection of endotoxin in the knee joint of the dog. (1975) (26)
Endotoxin inhibition of distension‐stimulated gastric acid secretion in rat: mediation by NO in the central nervous system (1995) (25)
Inflammatory properties of lipoxygenase products and the effects of indomethacin and BW755C on prostaglandin production, leukocyte migration, and plasma exudation in rabbit skin. (1982) (25)
Silent 5-HT A receptor antagonists: utility as research tools and therapeutic agents (1993) (25)
Endothelium-derived nitric oxide (1999) (25)
Induction and role of NO synthase in hypotensive hepatic failure. (1997) (25)
Use of the rabbit transverse stomach-strip to identify and assay prostacyclin, PGA2, PGD2 and other prostaglandins. (1979) (25)
Molecular genetic analysis of the duplication of human inducible nitric oxide synthase (NOS2) sequences. (1995) (24)
MODE OF ACTION OF BENOXAPROFEN (1984) (24)
Modulation of the conformational state of mitochondrial complex I as a target for therapeutic intervention (2017) (23)
A perfusion system for the long term study of macrophage activation (1992) (23)
The relative activity of prostacyclin (PGI2) and a stable analogue 6β‐PGI1 on the gastrointestinal and cardiovascular systems (1978) (23)
Mitochondrial dynamics, biogenesis, and function are coordinated with the cell cycle by APC/C CDH1. (2012) (23)
Effects of calcium and parathyroid hormone on prostacyclin synthesis by vascular tissue. (1987) (23)
The oxidation of alpha-tocopherol in human low-density lipoprotein by the simultaneous generation of superoxide and nitric oxide. (1993) (23)
Localisation of nitric oxide synthase within non-adrenergic, non-cholinergic nerves in the mouse anococcygeus (1993) (23)
Relative potency of prostacyclin, prostaglandin E1 and D2 as inhibitors of platelet aggregation in several species [proceedings]. (1977) (22)
Antithrombotic assessment and clinical potential of prostacyclin analogues. (1984) (22)
Persistent induction of nitric oxide synthase in tumours from mice treated with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid. (1998) (22)
Prostaglandins in the pathogenesis and prevention of vascular disease. (1987) (22)
Benoxaprofen does not inhibit formation of leukotriene B4 in a model of acute inflammation. (1984) (21)
Effect of prostacyclin on myogenic activity and adrenergic neuroeffector interaction in canine isolated veins. (1978) (21)
Elimination of prostacyclin (PGI2) and 6‐oxo‐PGF1α in anaesthetized dogs (1979) (21)
Adhesion of human platelets to collagen in the presence of prostacyclin, indomethacin and compound BW 755C. (1986) (21)
Evaluation of inhibitors of eicosanoid synthesis in leukocytes: possible pitfall of using the calcium ionophore A23187 to stimulate 5' lipoxygenase. (1985) (21)
Prostacyclin as a potent dilator of arterioles in the hamster cheek pouch [proceedings]. (1978) (21)
Prostacyclin (PGI2) inhibits the formation of platelet thrombi in arterioles and venules of the hamster cheek pouch (1997) (21)
Formation of prostacyclin (PGl2) by different layers of the arterial wall. (1977) (20)
An ultrastructural study of stored human platelets after washing using prostacyclin (1985) (20)
Pulmonary Inflammation Induced by a Recombinant Brugia malayi γ-glutamyl transpeptidase Homolog: Involvement of Humoral Autoimmune Responses (2001) (20)
An overview of antiplatelet and antithrombotic drugs. (1985) (19)
EXPERIMENTAL ASSESSMENT OF PROSTACYCLIN IN THE HARVESTING OF KIDNEYS FOR TRANSPLANTATION (1980) (19)
Inhibition of platelet activation by prostacyclin: possible consequences in coagulation and anticoagulation. (1981) (19)
Inactivation of nitric oxide by cytochrome c oxidase under steady-state oxygen conditions. (2010) (18)
The endogenous nitrovasodilator produced by the vascular endothelium. (1989) (18)
Influence of cholesterol feeding on the production of eicosanoids, tissue plasminogen activator and superoxide anion (O2-) by rabbit blood monocytes. (1986) (18)
Effect of eicosapentaenoic acid on eicosanoids formation by stimulated human polymorphonuclear leukocytes (1986) (18)
DIPYRIDAMOLE AND PLATELET FUNCTION (1978) (18)
Prostacyclin can Replace Heparin for Haemodialysis in Dogs (1979) (18)
Implications of prostacyclin generation for modulation of vascular tone. (1978) (18)
Techniques for the measurement of nitric oxide. (1995) (17)
Leukocytes and tissue injury: the use of eicosapentaenoic acid in the control of white cell activation. (1986) (17)
Enzymatic characterisation of recombinant murine inducible nitric oxide synthase. (1995) (17)
Mitochondria as pharmacological targets (2010) (17)
Prostacylin modulates the responses to leukotrienes C4 and D4 of guinea-pig airway smooth muscle (1984) (16)
Cardiomyopathy: a role for nitric oxide? (1995) (16)
Induction of nitric oxide synthase in rat intestine and its association with tissue injury (2005) (16)
Effect of SKF 525A on the release of nitric oxide and prostacyclin from endothelial cells. (1988) (16)
Inhibition of prostaglandin synthesis augments the effects of sympathetic nerve stimulation on the cat spleen. (1971) (16)
Enzymology, biochemistry and immunology (1992) (16)
Visualization of nitric oxide formation in cell cultures and living tissue. (1999) (16)
Evolution of nitric oxide. (1993) (15)
Polyunsaturated fatty acids and thrombosis (1979) (15)
PROSTACYCLIN CAN EITHER INCREASE OR DECREASE HEART RATE DEPENDING ON THE BASAL STATE (1982) (15)
Physiological and clinical aspects (1992) (15)
The anti-thrombotic effects of prostacyclin. (2009) (15)
Prostacyclin-release by bradykinin in vivo [proceedings]. (1979) (15)
The synthesis of eicosanoids induced by anaphylaxis in guinea-pig isolated lungs perfused via the trachea. (1986) (15)
PROSTACYCLIN (PGI2) INHIBITS THE FORMATION OF PLATELET THROMBI IN ARTERIOLES AND VENULES OF THE HAMSTER CHEEK POUCH (1997) (15)
Interrelationships between prostacyclin and thromboxane A2. (2008) (14)
The effect of prostacyclin on platelet aggregation and disaggregation in vivo. (1980) (14)
Ulceration induced by an endoperoxide analog and by indomethacin in the canine stomach. (1983) (14)
Prostacyclin-sensitive adenylate cyclase in cultured myocytes: differences between rabbit aorta and mesenteric artery. (1984) (14)
Some actions of prostacyclin (PGI2) on the cardiovascular system and the gastric microcirculation. (1978) (14)
Biological Activities of Some Metabolites and Analogues of Prostacyclin (1981) (14)
The differential response of a novel bioassay tissue, the rabbit transverse stomach-strip, to prostacyclin (PGI2) and other prostaglandins [proceedings]. (1977) (13)
Foetal erythrocytes exhibit an increased ability to scavenge for nitric oxide. (1998) (13)
Prostacyclin/thromboxane-mediated mechanisms in platelet-vascular wall interactions. (1985) (13)
Prostacyclin and the vascular endothelium. (1981) (13)
Prostaglandins and the mechanism of analgesia produced by aspirin‐like drugs (1973) (13)
Proceedings: Formation of prostaglandin endoperoxides and rabbit aorta contracting substance (RCS) by coupling two enzyme systems. (1976) (12)
Prostacyclin and Blood Coagulation (1981) (12)
The Role of Prostaglandins in Platelet-Vessel Wall Interactions (1982) (12)
626 A tender sinus does not always mean sinusitis (2000) (12)
Nitric Oxide: Role in Human Disease (2003) (12)
Carbon tetrachloride-induced eicosanoid synthesis and enzyme release from rat peritoneal leucocytes. (1985) (11)
Nitric oxide from L-arginine : a bioregulatroy system : proceedings of the symposium held at the Royal Society, London, 14-15 September, 1989 /editors, Salvador Moncada, E. Annie Higgs (1990) (11)
Arachidonic acid metabolism in inflammation and the mode of action of anti-inflammatory drugs. (1979) (11)
Prostacyclin--physiology and clinical uses. (1983) (11)
The release of lyso-PAF from guinea-pig lungs. (1985) (11)
Release of eicosanoids from isolated lungs of guinea-pigs exposed to pure oxygen: effect of dexamtethasone. (1986) (11)
Modulation of noradrenergic responses by nitric oxide from inducible nitric oxide synthase. (1997) (11)
Nitrergic modulation of cholinergic responses in the opossum lower oesophageal sphincter (1997) (11)
Prostacyclin production by rabbit aorta, pericardium, pleura, peritoneum and dura mater. (1978) (10)
Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera (2007) (10)
Mode of action of aspirin-like drugs. (1979) (10)
Interaction between anti-inflammatory drugs and inflammatory mediators. A reference to products of arachidonic acid metabolism. (1977) (10)
Prostaglandin X, the vascular metabolite of arachidonic acid responsible for relaxation of bovine coronary artery strips [proceedings]. (1977) (10)
Therapeutic Potential of NOS Inhibitors in Septic Shock (2000) (10)
Prostacyclin (PGI2) inhibits the formation of platelet thrombi induced by adenosine diphosphate (ADP) in vivo [proceedings]. (1977) (10)
Prostacyclin eliminates the thrombocytopenia associated with charcoal hemoperfusion and minimizes heparin and fibrinogen consumption. (1980) (10)
Biological actions of prostacyclin and its pharmacological use in platelet studies. (1985) (9)
The Vascular Endothelium II (2006) (9)
THE STRUCTURE OF PROSTAGLANDIN I 2 (1977) (9)
Regional haemodynamic changes in brattleboro rats during oral ingestion of L-nitroarginine methylester (L-NAME) (1990) (9)
INHALED CORTICOSTEROIDS FOR RESPIRATORY DISTRESS? (1985) (9)
6-oxo-Prostaglandin F1α and Thromboxane B2 in Uterine Vein Blood - A Possible Role in Menstrual Bleeding (1982) (9)
Nitrergic neurotransmission in the physiology of penile erection and pathophysiology of erectile dysfunction (2000) (8)
Characterization and biological significance of endothelium-derived relaxing factor. (1988) (8)
The effect of cyclo-oxygenase and thromboxane synthetase inhibitors on shock induced by injection of heterologous blood in cats. (1983) (8)
Can endogenous gaseous messengers control mitochondrial biogenesis in mammalian cells? (2004) (8)
Inhibitory effect of N(G)-monomethyl-L-arginine on endothelium-dependent relaxations to vasopressin (1990) (8)
Prostacyclin reduces the number of 'slow moving' leucocytes in hamster cheek pouch venules [proceedings]. (1978) (8)
Inhibition of human platelet aggregation by vitamin K. (1985) (8)
Nitric oxide mediates the vascular actions of cytokines in septic shock (1992) (8)
Does Prostaglandin Release Contribute to the Hypotension Induced by Inhibitors of Angiotensin Converting Enzyme (1983) (8)
"Ottorino Rossi" Award 1997. The biology of nitric oxide. (1997) (8)
[Nitric oxide: from endogenous vasodilator to biologic mediator]. (1990) (8)
Inflammatory effects of prostacyclin (PGI2) and 6-oxo-PGF1alpha in the rat paw. (1978) (7)
A2. Nitric oxide and bioenergetics: Physiology and pathophysiology (2007) (7)
The role of prostacyclin and thromboxane A2 in the regulation of platelet behaviour. (1980) (7)
Adventures in pharmacology, aspirin, prostacyclin and nitric oxide. (2004) (7)
RECIRCULATIONOF PROSTACYCLIN(PGI2)INTHE DOG (1978) (7)
Secretory function of vascular endothelium. (1987) (7)
Effect of prostacyclin on myogenic activity and adrenergic neuroeffector interaction in isolated canine veins. (1978) (7)
Release of vasoactive substances from guinea pig isolated lungs perfused via the trachea. (1987) (7)
Hydroxychloroquine/ chloroquine as a treatment choice or prophylaxis for Covid-19 at the primary care level in developing countries: A Primum non Nocere dilemma (2020) (7)
Nitric Oxide and the Cell: Proliferation, Differentiation, and Death (2017) (7)
Mitochondrial biogenesis as a cellular signaling framework (vol 67, pg 1, 2004) (2004) (7)
Physiological regulation and pathological inhibition of tissue respiration by nitric oxide in vivo (2000) (7)
GW273629 is a highly selective, short-acting iNOS (NOS-2) inhibitor both in vitro and in vivo: beneficial effects in endotoxin shock (2000) (7)
Formation of prostacyclin and its product 6-oxo-PGF1alpha by the gastric mucosa of several species [proceedings]. (1978) (6)
Neuronal nitric oxide synthase immunoreactivity in the respiratory tract of the frog, Rana temporaria (2017) (6)
Unstable Metabolites of Arachidonic Acid in Relation to Thrombosis (1979) (6)
Prostaglandin endoperoxides and thromboxanes: Formation and effects (2004) (6)
A comparison of the inhibitory effects of prostacyclin and carbacyclin on platelet adhesion to collagen. (1982) (6)
The modification of low density lipoprotein (LDL) by peroxynitrite and systems generating nitric oxide (NO) and superoxide (1993) (6)
Biotransformation of arachidonic acid in the circulation of the dog [proceedings]. (1978) (6)
Inducible nitric oxide synthase and inflammation (1999) (6)
The anti-inflammatory effect of glucocorticoid-induced phospholipase inhibitory proteins (1985) (6)
The Synthesis and Inhibition of Eicosanoids in Inflammation (1985) (6)
Biosyntesis and biological activity of LTB5 (1984) (5)
Role of Nitric Oxide in Endothelial Cell - Platelet Interactions (1991) (5)
Metabolism of leukotrienes B4 and B5 by human polymorphonuclear leukocytes (1986) (5)
Regulation of platelet function by nitric oxide (1993) (5)
[Significance of endogenous nitric oxide production for the effect of nitrates and in septic shock]. (1993) (5)
Leukotrienes in disease. Implications for drug development. (1985) (5)
The blockade of the local generation of prostaglandins explains the analgesic action of aspirin (1973) (5)
Some properties of rabbit aorta contracting substance-releasing factor (RCS-RF) [proceedings]. (1976) (5)
Endogenous nitric oxide is involved in hemodynamics disturbances in portal hypertensive (PH) rats (1991) (5)
Inhibition of vasculur nitric oxide synthesis by novel L-arginine analogues (1990) (5)
Prostacyclin modulates the responses to leukotrienes C4 and D4 of guinea-pig airway smooth muscle. (1984) (5)
Vascular Endothelium (2010) (5)
Prostaglandins and blood flow in the dog's knee joint. (1976) (5)
The Pharmacology and Clinical Potential of Prostacyclin (1980) (5)
869 – STIMULATION OF RENIN RELEASE BY PROSTACYCLIN (PGI2) IN ANAESTHETIZED DOGS (1978) (5)
The biological importance of the formation of nitric oxide from L-arginine (1990) (5)
Activated macrophages utilize glycolytic ATP to maintain mitochondrial membrane potential and prevent apoptotic cell death (2012) (5)
Nitric Oxide in the Cardiovascular System (1995) (5)
Nitric oxide in cardiovascular function and disease (2000) (5)
Generation of thromboxane A2-like activity from prostaglandin endoperoxides by polymorphonuclear leukocyte homogenates [proceedings]. (1976) (5)
Polyunsaturated fatty acids as precursors of prostaglandins. (1979) (5)
Discovery and Biological Relevance of the L-Arginine: Nitric Oxide Pathway (1990) (4)
Nitric oxide favours tumour-promoting inflammation through mitochondria-dependent and -independent actions on macrophages (2022) (4)
Neuronal nitric oxide synthase immunoreactivity in the respiratory tract of the frog,Rana temporaria (1995) (4)
Prostacyclin and Thromboxane A2 in Platelet Vessel Wall Interactions (1980) (4)
Thermospray tandem mass spectrometric analysis of oxygen incorporation into citrulline by nitric oxide synthase. (1991) (4)
Prostacyclin, EDRF and atherosclerosis. (1988) (4)
Endogenous nitric oxide asamodulator ofrabbit skeletal muscle microcirculation invivo (1990) (4)
Aminoguanidine promotes vasoconstriction and leukocyte adherence in rat mesentery through inhibition of constitutive nitric oxide synthase (1995) (4)
Bio-synthesis of PGD2 and TXB2 by rabbit blood monocytes. (1986) (4)
Nitric oxide, physiology, pathology and clinical relevance (1992) (4)
Drugs that modulate prostaglandins, prostacyclin, and thromboxane A2. (1982) (4)
[Role of nitric oxide in cell respiration]. (1998) (4)
Biosynthesis and function of prostacyclin (PGX) in the heart (1977) (3)
Endothelial dysfunction on cerebral small vessel disease (2019) (3)
Bioassay of prostacyclin and endothelium‐derived relaxing factor (EDRF) from porcine aortic endothelial cells (1986) (3)
Rapid development of atherosclerotic lesions in the rabbit carotid artery induced by perivascular manipulation: reply to the letter of R.M.K.W. Lee. (1990) (3)
La vía L-Arginina: óxido nítrico (1994) (3)
Corrigendum to “Mitochondrial biogenesis as a cellular signaling framework”: [Biochem. Pharmacol. 67 (2004) 1–15] (2004) (3)
[Production of prostacyclin and endothelium-derived relaxing factor from endothelial cells]. (1986) (3)
The renal haemodynamic and excretory actions of prostacyclin (PGI2) in anaesthetized dogs [proceedings]. (1978) (3)
JUXTAGLOMERULAR CELLS IN RAT-KIDNEY CONTAIN NITRIC-OXIDE SYNTHASE IMMUNOREACTIVITY (1992) (3)
Regulation ofgall bladder motility bythearginine- nitric oxide pathway inguinea pigs (1993) (3)
Detection of S-nitrosothiols in biological fluids (2000) (3)
Antithrombotic drugs in relation to prostaglandin metabolism. (1980) (3)
Prostaglandins and the mechanism of analgesia produced by aspirin‐like drugs (1997) (3)
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, regulate glycolysis during the cell cycle (2011) (2)
Nitric oxide and posttranslational modification of the vascular proteome (2007) (2)
Differential expression of inducible nitric oxide synthase in murine myocardium infected with wildtype or attenuated Coxsackievirus B3. (1997) (2)
Nitric oxide, a mediator of cellular communication (1990) (2)
Antiinflammatory effects of eicosapentaenoic acid: relevance to icosanoid formation. (1985) (2)
Prostacyclin and its analogues for the therapy of thromboembolic disorders. (1984) (2)
ATHEROSCLEROSIS MODEL. REPLY (1993) (2)
Anaphylactic release of platelet activating factor acether and eicosanoids from lungs of guinea pigs sensitized to ovalbumin aerosol. (1987) (2)
Nitric Oxide and Hypertension: Physiology and Pathophysiology (1997) (2)
Synthesis of eicosanoids by tissues of the synovial joint during the development of chronic erosive synovitis (2005) (2)
Erratum to: Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway (2017) (2)
National Health under new management (1997) (2)
Bradykinin Stimulates L-Arginine Transport and Nitric Oxide Release in Vascular Endothelial Cells (1993) (2)
ARACHIDONIC ACID METABOLITES IN THE CARDIOVASCULAR SYSTEM (1981) (2)
3.C.4 Nitric oxide (1997) (2)
Nitric oxide and hypoxia. In: Essays in Biochemistry - Oxygen sensing and hypoxia-induced responses. (2007) (2)
863 – PROSTACYCLIN (PGI2) PRODUCTION IN THE CAT SPLEEN (1978) (2)
Synthesis of 6-keto-PGF1alpha by ram seminal vesicle microsomes. (1977) (2)
Drugs that alter nitric oxide homeostasis: a reply. (1994) (2)
The "Sanchez-Medal" Lecture Award: nitric oxide 1994. (1994) (2)
Non-adrenergic non-cholinergic responses in the rabbit vaginal wall are mediated by nitrergic neurotransmission (1999) (2)
Biochemical Characterization ofS-Nitrosohemoglobin (1999) (2)
Prostacyclin, biological role and therapeutic potential (1981) (1)
RAT MESANGIAL CELLS IN CULTURE CONTAIN NITRIC-OXIDE SYNTHASE IMMUNOREACTIVITY (1992) (1)
Mitochondria of activated macrophages utilize glycolytic ATP to maintain membrane potential and prevent apoptosis (2010) (1)
Nitric oxide (2015) (1)
11. Cytoprotective actions of nitric oxide in hepatic inflammation (2017) (1)
834 – ENHANCEMENT OF ANAPHYLACTIC MEDIATOR RELEASE FROM GUINEA-PIG LUNG BY 15-HYDROPEROXY ARACHIDONIC ACID (1978) (1)
The Biological Importance and Therapeutic Potential of Prostacyclin (1981) (1)
Bioassay of prostacyclin and endothelium‐derived relaxing factor (EDRF) from porcine aortic endothelial cells (1997) (1)
868 – PROSTACYCLIN (PGI2) AND ARACHIDONIC ACID. BIOTRANSFORMATION IN THE CIRCULATION OF THE DOG (1978) (1)
Nitric Oxide and Cell Metabolism Dysfunction in the Metabolic Syndrome (2005) (1)
Inhibition of NADH-ubiquinone reductase by nitric oxide is mediated by intramitochondrial peroxynitrite (2000) (1)
Erratum: Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals (Proceedings of The National Academy of Sciences USA (February 15, 2005) 102:7 (2649-2654)) (2005) (1)
Regional and cardiac haemodynamic effects of NG-nitro-L-arginine methyl ester (L-NAME) in conscious, Long???Evans rats (1990) (1)
Nitric oxide in mitochondrial function and injury (1999) (1)
Symmetric and asymmetric dimethylarginine inhibit arginine transport and nitric oxide synthesis in J774 macrophages (1996) (1)
Prostacyclin and the Mechanism of Action of Antithrombotic Drugs (1979) (1)
Prostacyclin and Its Therapeutic Potential (1982) (1)
Redox signaling: Mechanisms and Biological Impact (2006) (1)
Elimination of prostacyclin (PGI2) and 6-oxo-PGF1 alpha in anaesthetized dogs. (1979) (1)
The Use of Prostacyclin [PGI2) During Charcoal Haemoperfusion (1979) (1)
Leukotrienes in Disease (1985) (1)
Mitochondria, nitric oxide and cell bioenergetics (2009) (1)
Transient Glycolysis Enables Mitochondrial Fusion and Stimulates S Phase Entry: The Role of FoxO3a (2014) (1)
Prostacyclin-release by bradykinin in vivo (2007) (1)
Prostacyclin: Production by Vascular Endothelium and Effects on Platelet Aggregation (1979) (1)
Kinetics of nitric oxide synthase: a reply (1990) (1)
Clinical significance of arachidonic acid metabolites in blood vessels and platelets (1986) (1)
The L-Arginine: Nitric Oxide Pathway in Physiology and Pathology (1992) (1)
Prostacyclin eliminates the bioincompatibility of charcoal haemoperfusion. (1979) (1)
2170 – PROSTACYCLIN (PGI2) - A SPECIFIC CORONARY DILATING AGENT IN RAT, GUINEA PIG AND RABBIT (1978) (1)
Expression of inducible nitric oxide synthase in the developing mouse placenta. (1996) (1)
Identification of Prostacyclin, Thromboxane A2 and Prostaglandins in Pharmacological Experiments (1980) (1)
Endothelium-Derived Vasodilators (1989) (1)
Mitochondrial biogenesis in mammals: the role of nitric oxide (2004) (1)
Derivatives of prostaglandins and drugs containing these derivatives (1977) (0)
Exogenous nitric oxide induces acute inflammation (1992) (0)
AN OVERVIEW OF GASEOUS SIGNALING BY NITRIC OXIDE (2003) (0)
3. Interactions between nitric oxide and cytochrome-c oxidase in turnover (2017) (0)
Role of conformational changes in mitochondrial complex I in the hypoxic response (2010) (0)
Nitric oxide: discovery and biological relevance (2000) (0)
Koninklijke Academie voor Geneeskunde van België. Nitric oxide and cell respiration: physiology and pathology (1999) (0)
IS ATHEROSCLEROSIS A DISEASE OF THE OUTSIDE OF ARTERIES? (1987) (0)
Inhibition of complex I and GAPDH enzymes by NO is preceded by a decrease in GSH concentrations in several cell lines (2000) (0)
COMPARATIVE ACTIONS OF IONOPHORE A23187 AND BRADYKININ ON THE INTEGRITY OFBOVINE ENDOTHELIAL CELLS IN CULTURE AND ON THE RELEASE OF PROSTACYCLIN AND NITRIC OXIDE (1991) (0)
26. CD95-induced calcium release and apoptosis are regulated by nitric oxide via a cGMP dependent pathway in human γδ T-lymphocytes (2017) (0)
12. Activation of nuclear factor-κB and activator protein- I, and steady-state level of mRNA encoding tumour necrosis factor-α and inducible nitric oxide synthase in rat liver during different types of cell proliferation (2017) (0)
22. Evidence that nitric oxide induces apoptotic cell death in the lateral geniculate nucleus of dark-reared rabbits (2017) (0)
Erratum (1976) (0)
Nitric oxide and the cell : proliferation, differentiation and death : proceedings of the symposium held in Calabria, Italy, in September 1996, under the auspices of the British and Italian Pharmalogical Societies (1998) (0)
Putative role of Nrf2 as a tumor suppressor through inhibition of angiogenesis (2012) (0)
Interaction between the L-arginine: No pathway and morphine (1992) (0)
Óxido nítrico: papel del NO en la respiración celular (2001) (0)
19. Neuromodulatory and neuroprotective actions of nitric oxide in the striatum (2017) (0)
Inhibition of dimethylarginine dimethylaminohydrolase: a novel mechanism for the regulation of blood pressure (1995) (0)
27. Nitric oxide-initiated apoptotic cell death: activating and antagonistic signalling components (2017) (0)
S6.5 Nitric oxide and HIF-1α synergise to activate glycolysis during inflammation (2008) (0)
Retraction Notice to: Mitochondrial Dynamics, Biogenesis, and Function Are Coordinated with the Cell Cycle by APC/CCDH1 (2012) (0)
Morphological evidence for nitric oxide production by the human enteric nervous system (1993) (0)
(All-Z) -5,8,11,14,17-eicosapentaenoic acid and / or derivatives thereof containing formulations, as well as processes for their preparation (1978) (0)
C20RESISTANCE TO HYPERTENSION AND INCREASED ENDOTHELIAL NITRIC OXIDE SYNTHASE ACTIVITY IN THE SABRA SBN RATS. (1995) (0)
Interaction between cytochrome c oxidase and nitric oxide: physiological and pathophysiological consequences (2009) (0)
Pharmaceutical combination, processes for their preparation and their use (1977) (0)
Synergy between medicinal chemistry and biological research. (2014) (0)
Adventures in pharmacology, aspirin, prostacyclin and nitric oxide. (2004) (0)
The cross-talk between nitric oxide and sphingomyelinases regulates apoptosis induction by tumour necrosis factor-α (2003) (0)
New insights into the biological significance of nitric oxide: cytochrome c interactions (2007) (0)
Commentary on "Prostacyclin" (PGI2) inhibits the formation of platelet thrombi in arterioles and venules of the hamster cheek pouch". (1997) (0)
European Perspectives in Cardiology European Perspectives in Cardiology (2006) (0)
Protective effects ofinhibitors ofnitric oxide synthase in immunecomplex-induced vasculitis (1992) (0)
Anti-leukocyte properties of a novel non NO-based soluble guanylate cyclase activator, BAY 41-2272 (2003) (0)
Elevation of glutathione in astrocytes exposed to nitric oxide (2001) (0)
4. Nitric oxide interactions with mitochondria and oxygen metabolism (2017) (0)
Abstracts (2007) (0)
Increased concentrations ofnitrite insynovial fluid andserum samples suggestincreased nitric oxide synthesis inrheumatic diseases (1992) (0)
28. Nitric oxide-induced apoptosis of RAW264.7 peritoneal macrophages: relationship between apoptosis and integrin expression profiles (2017) (0)
Inhibition of endothelial nitric oxide production does not antagonize hindquarters dilatation to endothelin-1 (1989) (0)
29. Nitric oxide, p53 and cancer (2017) (0)
Fatty acids, derivatives thereof and drugs containing it (1979) (0)
Óxido nítrico: antecedentes históricos (2001) (0)
PROGRESS IN CEREBROVASCULAR DISEASE Biology and Therapeutic (2008) (0)
A pharmaceutical preparation for prevention of platelet aggregation (1978) (0)
Leucocyte infiltration andcartilage proteoglycan loss inimmunearthritis intherabbit (1988) (0)
20. Microdialysis study in vivo of the nitric oxide/cGMP pathway in the hippocampus and cerebellum of adult and aged rats (2017) (0)
LETTERS TO THE EDITOR (1993) (0)
Nitrergic-noradrenergic interaction in the penile corpus cavernosum of diabetic rabbits (2000) (0)
S8.22 Regulation of mitochondrial complex I by nitric oxide during hypoxia (2008) (0)
Regulación de la homeostasis vascular mediante óxido nítrico (1994) (0)
Nitric oxide production by benign and malignant breast tissue (1993) (0)
Abstracts of IV International Workshop on "Nitric Oxide in Cancer", Seville, Spain, March 13-14, 2015 (2015) (0)
The Priestley Lecture 1997 Nitric Oxide (1998) (0)
N(G)-monomethyl-L-arginine inhibits thrombin-stimulated production of cyclic GMP in cultured porcine aortic endothelial cells (1990) (0)
Nitric oxide on cell respiration: Its role in cell survival or death. (2001) (0)
Risk in the Metabolic Syndrome ? Defective Mitochondrial Biogenesis : A Hallmark of the High Cardiovascular (2007) (0)
Cyclic ethers, process for their preparation and pharmaceutical compositions containing them (1977) (0)
Interactions between endogenous nitric oxide and tachykinins in the modulation of spontaneous motility of rat duodenum (1995) (0)
From endothelium-derived relaxing factor to nitric oxide. The role of vascular endothelium in the control of blood flow (1990) (0)
1. Nitric oxide, mitochondria and cytotoxicity (2017) (0)
1. Nitric oxide, mitochondria and cytotoxicity (2017) (0)
P/17 Nitric oxide: Mitochondrial interactions in physiology and pathophysiology (2008) (0)
Effects of Endogenous Nitric Oxide on Basal Vasomotor Tone and Stimulated Endothelium-Dependent Responses in the Coronary Arterial Circulation (1993) (0)
Mitochondrial dysfunction and HIF1&agr; stabilization in inflammation (2012) (0)
9. Control of cell growth by nitric oxide: the role of cGMP-dependent and -independent events occurring at various steps of growth factor-activated signalling processes (2017) (0)
7. Differential inhibitory action of nitric oxide and peroxynitrite on the R2 subunit of ribonucleotide reductase (2017) (0)
Neuroprotection by PARP-1 during endogenous oxidative stress (2007) (0)
PFKFB3 Depletion Activates β-Cell Replication by Cell Competitive Culling of Compromised β-Cells Under Stress (2021) (0)
Nitric oxide and bioenergeties: Physiology and pathophysiology (2007) (0)
Prostacyclin—recent developments (1981) (0)
5. Resistance factors for nitrosative and oxidative stress (2017) (0)
drug combinations comprising prostacyclin or dihydroprostacycline (1978) (0)
United Kingdom - Director of the Cruciform Project (1997) (0)
A process for the extraction, isolation and synthesis of prostaglandin (1977) (0)
Prostacyclin is a Heparin-Sparing Agent during Haemodialysis (1978) (0)
Nitric oxide synthases in mammals 251 OCH 3 H 2 NNH (2005) (0)
The biology of nitric oxide : proceedings of the 4th International Meeting on the Biology of Nitric Oxide, Amelia Island, Florida, U.S.A. (1996) (0)
31. Nitric oxide priming inhibits nitric oxide-mediated apoptosis (2017) (0)
Paracoccus complex I as a model for the bovine enzyme: Developing methods to study proton translocation (2012) (0)
β-cell-specific deletion of PFKFB3 restores cell fitness competition and physiological replication under diabetogenic stress (2022) (0)
Analogifremgangsmaade for preparing prostaglandin derivatives (1977) (0)
The differential effect of nitric oxide on glutathione metabolism in astrocytes and neurons (2002) (0)
Nitric oxide and mitochondrial Interactions: physiology and pathophysiology (2010) (0)
16. Role of nitric oxide and nerve growth factor in the mechanisms of neurotoxicity induced by the HIV-1 coat protein gp l 20 in rat (2017) (0)
Abstract 560: Inflammation Converts Glucose Into A Deleterious Agent In Human Aortic Smooth Muscle Cells (2014) (0)
24. A further insight into the mechanism of lipoxygenase inhibition by nitric oxide (2017) (0)
Linking metabolic requirements and cell cycle progression: the role of Myc (2013) (0)
Nitric oxide and cell respiration: Physiology and pathophysiology (1998) (0)
THE ROLES OF NITRIC-OXIDE IN ENDOTOXIN-SHOCK (1992) (0)
[Nitric oxide and Hirschsprung's disease: a causal relation biochemically, immunohistochemically and functionally demonstrated]. (1994) (0)
Frompollutant gastobiological messenger: thediverse actions ofnitric oxide incancer (2002) (0)
Regulación de la motilidad de la vesícula biliar mediante óxido nítrico (1994) (0)
AMPKa1 regulates the antioxidant defence of the vascular endothelial cells (2009) (0)
Induction of Early Atherosclerosis by Perivascular Manipulation (1988) (0)
Nitric oxide…from the beginning (2012) (0)
8. Hydroxyguanidines as modifiers of cell proliferation and death: a possible role for nitric oxide (2017) (0)
Peter Debyeprize 1994 on Molecular Biology of Cardiovascular Diseases--Fundamental and Clinical Aspects Awarded to Drs Lydie Rappaport, Ketty Schwartz, and Bernard Swynghedauw from Unit 127 of INSERM, Paris, France. Committee of Deans, University of Limburg. (1994) (0)
Impaired Responsiveness to Endogenous Vasoconstrictors and Endothelium-Derived Vasoactive Factors in Cirrhosis (1994) (0)
13. The mechanism of nitric oxide-induced apoptosis in the pancreatic β-cell may involve cGMP and protein kinase G (2017) (0)
THE PENTOSE PHOSPHATE PATHWAY IS A KEY FACTOR IN HIGH GLUCOSE- ASSOCIATED VASCULAR DAMAGE (2018) (0)
Prostaglandins And Uterine Bleeding (1981) (0)
10. Nitric oxide controls cell proliferation during Drosophila development (2017) (0)
O15. Nitric oxide, mitochondria and their dynamics in myogenesis (2008) (0)
The blockade of the local generation of prostaglandins explains the analgesic action of aspirin. (1973) (0)
The role of nitric oxide in atherosclerosis (1995) (0)
Commentary on "Bioassay of prostacyclin and endothelium-derived relaxing factor (EDRF) from porcine aortic endothelial cells. (1997) (0)
Nitric oxide triggers the early reduction of mitochondrial cytochromes in respiring mammalian cells (2006) (0)
15. The role of astroglial cell-derived nitric oxide and prostanoids in death and repair mechanisms in the brain (2017) (0)
Prostacyclin: its biosynthesis, actions and clinical potential. (1981) (0)
21. Mechanisms of neuronal apoptosis elicited by glutamate or nitric oxide donors (2017) (0)
Atherosclerosis model. (1993) (0)
23. Nitric oxide and prostaglandins in inflammation (2017) (0)
THE HARNESSING OF GLYCOLYSIS AND GLUTAMINOLYSIS FOR CELL PROLIFERATION (2011) (0)
The biology of nitric oxide : proceedings of the 6th International Meeting on the Biology of Nitric Oxide, held in Stockholm, Sweden, in September 1999 (2000) (0)
18. Nitric oxide mediates differentiation and survival of neuronal cells (2017) (0)
Retraction: Recombinant Migration Inhibitory Factor Induces Nitric Oxide Synthase in Murine Macrophages (2012) (0)
Nitric oxide : brain and immune system : proceedings of the conference held in Calabria, Italy in Autumun 1992, under the auspices of Società Italiana di Neuroimmunomodulazione (SINIM) (1993) (0)
The biology of nitric oxide : proceedings of the 5th International Meeting on the Biology of Nitric Oxide, September 1997, Kyoto, Japan (1998) (0)
S5/2 Regulation of mitochondrial dynamics by nitric oxide is a key event in myogenesis (2008) (0)
Sergio Henrique Ferreira (1934–2016) (2016) (0)
25. The role of nitric oxide in T-cell functions (2017) (0)
cardiology pioneer speaks to Mark Nicholls about the discovery of prostacyclin and his research in the field of nitric oxide (0)

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