Shinya Yamanaka | Academic Influence

Why Is Shinya Yamanaka Influential?

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Shinya Yamanaka is the director of Center for iPS Cell Research and Application (iPS – induced Pluripotent Stem Cell), senior investigator for the J. David Gladstone Institutes, a professor for Kyoto University’s Institute for Frontier Medical Services, and a professor of anatomy for the University of California at San Francisco. He studied at Osaka Kyoiku University before earning his M.D. at Kobe University and his Ph.D. from Osaka City University Graduate School. He completed a residency in orthopedic surgery at National Osaka Hospital and a postdoctoral fellowship for the J. David Gladstone Institutes of Cardiovascular Disease.

When it appeared that being a surgeon wasn’t really his strength, he went into research at Nara Institute of Science and Technology. So began his career as a professor and researcher that earned him a Nobel Prize in 2012.

In 2012, Yamanaka and his colleague, Sir John B. Gurdon, were recognized with the Nobel Prize in Physiology or Medicine for their work with stem cells that found that mature cells could become pluripotent, if reprogrammed correctly.

His work has also been recognized with a Kyoto Prize, Balzan Prize for Stem Cells, Wolf Prize in Medicine, Millennium Technology Prize, and a Breakthrough Prize in Life Sciences.

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According to Wikipedia, is a Japanese stem cell researcher and a Nobel Prize laureate. He serves as the director of Center for iPS Cell Research and Application and a professor at the Institute for Frontier Medical Sciences at Kyoto University; as a senior investigator at the UCSF-affiliated Gladstone Institutes in San Francisco, California; and as a professor of anatomy at University of California, San Francisco . Yamanaka is also a past president of the International Society for Stem Cell Research .

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Shinya Yamanaka's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Papers

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors (2006) (23027)
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors (2007) (15621)
Generation of germline-competent induced pluripotent stem cells (2007) (4218)
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells (2003) (3268)
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts (2008) (2815)
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors (2008) (1979)
A more efficient method to generate integration-free human iPS cells (2011) (1623)
Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. (2005) (1369)
Suppression of induced pluripotent stem cell generation by the p53–p21 pathway (2009) (1293)
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells (2008) (1063)
Nanog Is the Gateway to the Pluripotent Ground State (2009) (1033)
Induction of pluripotent stem cells from fibroblast cultures (2007) (1008)
Immunogenicity of induced pluripotent stem cells. (2011) (909)
Variation in the safety of induced pluripotent stem cell lines (2009) (866)
Induced pluripotent stem cell technology: a decade of progress (2017) (856)
Visfatin: A Protein Secreted by Visceral Fat That Mimics the Effects of Insulin (2005) (756)
Induced pluripotent stem cells: past, present, and future. (2012) (748)
Nuclear reprogramming to a pluripotent state by three approaches (2010) (746)
Hypoxia enhances the generation of induced pluripotent stem cells. (2009) (735)
A Fresh Look at iPS Cells (2009) (727)
Strategies and new developments in the generation of patient-specific pluripotent stem cells. (2007) (712)
Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness. (2013) (641)
mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells (2004) (593)
Autologous Induced Stem‐Cell–Derived Retinal Cells for Macular Degeneration: Brief Report (2017) (588)
A decade of transcription factor-mediated reprogramming to pluripotency (2016) (571)
An Efficient Nonviral Method to Generate Integration‐Free Human‐Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells (2013) (555)
Elite and stochastic models for induced pluripotent stem cell generation (2009) (522)
Reactivation of the Paternal X Chromosome in Early Mouse Embryos (2004) (516)
Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced Pluripotent Stem Cells (2008) (503)
Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells (2012) (494)
Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury (2010) (491)
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage (2011) (483)
Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9 (2014) (468)
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice (2011) (464)
Modeling familial Alzheimer's disease with induced pluripotent stem cells. (2011) (457)
A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells (2014) (425)
Promotion of direct reprogramming by transformation-deficient Myc (2010) (380)
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1 (2011) (376)
Steps Toward Safe Cell Therapy Using Induced Pluripotent Stem Cells (2013) (374)
iPS cells: a game changer for future medicine (2014) (360)
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells (2003) (358)
Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. (2015) (350)
Induced Pluripotent Stem Cells (2011) (339)
Premature Termination of Reprogramming In Vivo Leads to Cancer Development through Altered Epigenetic Regulation (2014) (336)
Generation of retinal cells from mouse and human induced pluripotent stem cells (2009) (318)
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability (2009) (305)
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells (2010) (294)
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture (2011) (288)
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells (2012) (281)
Fbx15 Is a Novel Target of Oct3/4 but Is Dispensable for Embryonic Stem Cell Self-Renewal and Mouse Development (2003) (278)
Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells. (2014) (272)
Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. (2013) (267)
Pluripotent Stem Cell-Based Cell Therapy-Promise and Challenges. (2020) (266)
Efficient and Scalable Purification of Cardiomyocytes from Human Embryonic and Induced Pluripotent Stem Cells by VCAM1 Surface Expression (2011) (251)
Induced pluripotent stem cells: opportunities and challenges (2011) (250)
Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy (2009) (245)
Generation of mouse-induced pluripotent stem cells with plasmid vectors (2010) (241)
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues (2010) (235)
Induced pluripotent stem cells in medicine and biology (2013) (234)
Induction of pluripotent stem cells from mouse fibroblasts by four transcription factors (2007) (234)
Direct Comparison of Autologous and Allogeneic Transplantation of iPSC-Derived Neural Cells in the Brain of a Nonhuman Primate (2013) (229)
The Use of Induced Pluripotent Stem Cells in Drug Development (2011) (226)
Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins (2005) (224)
Pluripotency and nuclear reprogramming (2008) (223)
Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture. (2013) (219)
Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity (2012) (217)
Toward the development of a global induced pluripotent stem cell library. (2013) (211)
Rethinking Differentiation: Stem Cells, Regeneration, and Plasticity (2014) (207)
iPS cell technologies: significance and applications to CNS regeneration and disease (2014) (204)
Dental Pulp Cells for Induced Pluripotent Stem Cell Banking (2010) (200)
The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes. (2014) (195)
Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential (2014) (193)
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. (2010) (191)
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells (2013) (190)
iPS cells: a source of cardiac regeneration. (2011) (177)
The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. (2009) (175)
In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. (2009) (171)
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration (2010) (169)
Efficient Detection and Purification of Cell Populations Using Synthetic MicroRNA Switches. (2015) (169)
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice* (2004) (166)
[Induction of pluripotent stem cells from mouse fibroblast cultures]. (2006) (166)
Induced Pluripotent Stem Cells 10 Years Later: For Cardiac Applications (2017) (163)
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease (2011) (157)
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis (2017) (157)
Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells (2010) (156)
Adipogenic differentiation of human induced pluripotent stem cells: Comparison with that of human embryonic stem cells (2009) (154)
Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity. (2016) (150)
Gingival Fibroblasts as a Promising Source of Induced Pluripotent Stem Cells (2010) (148)
Induced Pluripotent Stem Cells and Their Use in Human Models of Disease and Development. (2019) (141)
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts (2009) (141)
MHC matching improves engraftment of iPSC-derived neurons in non-human primates (2017) (135)
Enhanced engraftment, proliferation, and therapeutic potential in heart using optimized human iPSC-derived cardiomyocytes (2016) (135)
Induction and Enhancement of Cardiac Cell Differentiation from Mouse and Human Induced Pluripotent Stem Cells with Cyclosporin-A (2011) (134)
Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells (2006) (134)
Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development. (2013) (131)
Role of the phosphoinositide 3-kinase pathway in mouse embryonic stem (ES) cells. (2005) (131)
Intracellular signaling pathways regulating pluripotency of embryonic stem cells. (2006) (129)
Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation (2004) (129)
Broader implications of defining standards for the pluripotency of iPSCs. (2009) (126)
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells* (2005) (122)
Induction and Isolation of Vascular Cells From Human Induced Pluripotent Stem Cells—Brief Report (2009) (116)
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts (2013) (115)
Cell Therapy Using Human Induced Pluripotent Stem Cell‐Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice (2015) (115)
Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia (2014) (114)
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. (2012) (113)
Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm. (2014) (113)
Direct cardiac reprogramming: progress and challenges in basic biology and clinical applications. (2015) (111)
From Genomics to Gene Therapy: Induced Pluripotent Stem Cells Meet Genome Editing. (2015) (108)
Focal Transplantation of Human iPSC-Derived Glial-Rich Neural Progenitors Improves Lifespan of ALS Mice (2014) (107)
Reprogramming somatic cells towards pluripotency by defined factors. (2007) (107)
Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier (2013) (107)
Efficient and Rapid Induction of Human iPSCs/ESCs into Nephrogenic Intermediate Mesoderm Using Small Molecule-Based Differentiation Methods (2014) (105)
Characterization of Dendritic Cells and Macrophages Generated by Directed Differentiation from Mouse Induced Pluripotent Stem Cells (2009) (102)
Induced pluripotent stem cells and reprogramming: seeing the science through the hype (2009) (102)
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway* (2005) (101)
Generation of Human Melanocytes from Induced Pluripotent Stem Cells (2011) (101)
Human Induced Pluripotent Stem Cells on Autologous Feeders (2009) (99)
Patient-specific pluripotent stem cells become even more accessible. (2010) (98)
Transplantation of mouse induced pluripotent stem cells into the cochlea (2009) (96)
Induction of pluripotency by defined factors (2011) (96)
A developmental framework for induced pluripotency (2015) (94)
Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming. (2013) (92)
New advances in iPS cell research do not obviate the need for human embryonic stem cells. (2007) (92)
Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis (2011) (92)
Comparison of human mesenchymal stem cells derived from bone marrow, synovial fluid, adult dental pulp, and exfoliated deciduous tooth pulp. (2016) (91)
Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation (2013) (87)
Bioengineered Myocardium Derived from Induced Pluripotent Stem Cells Improves Cardiac Function and Attenuates Cardiac Remodeling Following Chronic Myocardial Infarction in Rats (2012) (86)
Efficient reprogramming of human and mouse primary extra‐embryonic cells to pluripotent stem cells (2009) (86)
Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes (2010) (82)
To be immunogenic, or not to be: that's the iPSC question. (2013) (81)
Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice (2013) (80)
Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes (2014) (80)
Concise Review: Laying the Groundwork for a First‐In‐Human Study of an Induced Pluripotent Stem Cell‐Based Intervention for Spinal Cord Injury (2018) (76)
Suppression of facilitative glucose transporter 1 mRNA can suppress tumor growth. (2000) (73)
Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells (2014) (72)
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation (2006) (70)
Enhanced Therapeutic Effects of Human iPS Cell Derived-Cardiomyocyte by Combined Cell-Sheets with Omental Flap Technique in Porcine Ischemic Cardiomyopathy Model (2017) (70)
Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors (2011) (68)
Generation and characterization of human induced pluripotent stem cells. (2009) (67)
MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells (2016) (67)
Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency. (2017) (64)
Harmonizing standards for producing clinical-grade therapies from pluripotent stem cells (2014) (64)
Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. (2016) (64)
Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. (2012) (62)
The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth (2015) (59)
Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. (2010) (59)
Rapid and deep profiling of human induced pluripotent stem cell proteome by one-shot NanoLC-MS/MS analysis with meter-scale monolithic silica columns. (2013) (58)
BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence (2016) (56)
Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells (2016) (56)
Global splicing pattern reversion during somatic cell reprogramming. (2013) (55)
Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo. (2013) (54)
Germline development from human pluripotent stem cells toward disease modeling of infertility. (2012) (54)
Computational image analysis of colony and nuclear morphology to evaluate human induced pluripotent stem cells (2014) (52)
Fabrication and Thermal Properties of Carbon Nanotube/Nickel Composite by Spark Plasma Sintering Method (2007) (52)
Evolutionarily conserved non-AUG translation initiation in NAT1/p97/DAP5 (EIF4G2). (2005) (51)
Defining Developmental Potency and Cell Lineage Trajectories by Expression Profiling of Differentiating Mouse Embryonic Stem Cells (2008) (50)
Orderly hematopoietic development of induced pluripotent stem cells via Flk‐1+ hemoangiogenic progenitors (2009) (50)
Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells. (2010) (49)
Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells (2018) (49)
Recent policies that support clinical application of induced pluripotent stem cell-based regenerative therapies (2016) (48)
Development of a global network of induced pluripotent stem cell haplobanks. (2015) (47)
Patient-Specific Human Induced Pluripotent Stem Cell Model Assessed with Electrical Pacing Validates S107 as a Potential Therapeutic Agent for Catecholaminergic Polymorphic Ventricular Tachycardia (2016) (46)
Induced 2C Expression and Implantation-Competent Blastocyst-like Cysts from Primed Pluripotent Stem Cells (2019) (46)
Delivery of Full-Length Factor VIII Using a piggyBac Transposon Vector to Correct a Mouse Model of Hemophilia A (2014) (45)
Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells (2013) (44)
Towards Precision Medicine With Human iPSCs for Cardiac Channelopathies. (2019) (43)
SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells (2016) (42)
Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells (2015) (41)
Essential Roles of ECAT15-2/Dppa2 in Functional Lung Development (2011) (41)
Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA‐binding protein with broad RNA targets (2006) (39)
A chemical probe that labels human pluripotent stem cells. (2014) (37)
Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5) (2006) (37)
Circulating osteocrin stimulates bone growth by limiting C-type natriuretic peptide clearance (2017) (36)
Identification of genes involved in tumor-like properties of embryonic stem cells. (2006) (35)
Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program (2016) (34)
KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency (2015) (33)
Stem cells assessed (2012) (33)
Induction of pluripotency by defined factors. (2010) (32)
Of Mice and Humans (2011) (30)
Genome‐wide DNA methylation profile of tissue‐dependent and differentially methylated regions (T‐DMRs) residing in mouse pluripotent stem cells (2010) (29)
Density functional study of tetrahedral manganese clusters (2003) (28)
First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol (2021) (27)
Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models (2016) (27)
An update on stem cell biology and engineering for brain development (2017) (27)
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies (2009) (26)
The winding road to pluripotency (Nobel Lecture). (2013) (26)
Epigenetic foundations of pluripotent stem cells that recapitulate in vivo pluripotency (2017) (25)
Ab initio extended density functional theory for strongly correlated electron systems: Fundamental aspects of the broken-symmetry approach and possible applications for molecular material design (2004) (25)
Reprogramming of somatic cells to pluripotency. (2010) (23)
Ekiden to iPS Cells (2009) (23)
The homeobox gene DLX4 promotes generation of human induced pluripotent stem cells (2014) (23)
A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of autologous human somatic stem cells☆ (2015) (21)
Generation and Characterization of Induced Pluripotent Stem Cells from Aid-Deficient Mice (2014) (20)
The fate of cell reprogramming (2014) (20)
ECAT11/L1td1 Is Enriched in ESCs and Rapidly Activated During iPSCGeneration, but It Is Dispensable for the Maintenance and Induction of Pluripotency (2011) (19)
Glis1, a unique pro-reprogramming factor, may facilitate clinical applications of iPSC technology (2011) (19)
MYC Releases Early Reprogrammed Human Cells from Proliferation Pause via Retinoblastoma Protein Inhibition. (2018) (18)
Efficient CRISPR/Cas9‐Based Genome Engineering in Human Pluripotent Stem Cells (2016) (18)
ERas is Expressed in Primate Embryonic Stem Cells but not Related to Tumorigenesis (2009) (18)
Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins (2016) (18)
Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells (2016) (17)
Labor pains of new technology: direct cardiac reprogramming. (2012) (17)
A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of autologous human induced pluripotent stem(-like) cells☆ (2015) (16)
Practical Integration‐Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells (2015) (16)
Making steady progress on direct cardiac reprogramming toward clinical application. (2013) (16)
Circulatory CNP Rescues Craniofacial Hypoplasia in Achondroplasia (2017) (15)
Design and synthesis of functional layered nanocomposites (1991) (15)
Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells. (2020) (15)
Donor Recruitment and Eligibility Criteria for HLA-Homozygous iPS Cell Bank in Japan (2014) (15)
A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of allogeneic human somatic stem cells☆ (2015) (14)
Fabrication and Thermal Evaluation of Carbon Nanotube/Aluminium composite by Spark Plasma Sintering Method (2006) (14)
Involvement of ER Stress in Dysmyelination of Pelizaeus-Merzbacher Disease with PLP1 Missense Mutations Shown by iPSC-Derived Oligodendrocytes (2015) (14)
A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of allogeneic human induced pluripotent stem(-Like) cells☆ (2015) (13)
Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death (2018) (13)
Drosophila NAT1, a homolog of the vertebrate translational regulator NAT1/DAP5/p97, is required for embryonic germband extension and metamorphosis (2007) (13)
A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from the processing of human embryonic stem cells☆ (2015) (12)
Perspectives for induced pluripotent stem cell technology: new insights into human physiology involved in somatic mosaicism. (2014) (12)
Dual inhibition of TMPRSS2 and Cathepsin Bprevents SARS-CoV-2 infection in iPS cells (2021) (12)
Base-Resolution Methylome of Retinal Pigment Epithelial Cells Used in the First Trial of Human Induced Pluripotent Stem Cell-Based Autologous Transplantation (2019) (12)
Retraction (2007) (12)
Self-Renewal and Mouse Development Dispensable for Embryonic Stem Cell Fbx 15 Is a Novel Target of Oct 3 / 4 but Is (2003) (10)
C-type natriuretic peptide restores impaired skeletal growth in a murine model of glucocorticoid-induced growth retardation. (2016) (9)
The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency (2020) (8)
New Models for Therapeutic Innovation from Japan (2017) (7)
Anti-A b Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer ’ s Disease (2011) (7)
Utilization of digital differential display to identify novel targets of Oct3/4. (2006) (7)
Thermal Properties of Carbon Nanotube/Nickel Composites Fabricated by Hetero Aggregation (2006) (7)
Bringing Induced Pluripotent Stem Cell Technology to the Bedside (2018) (7)
Application of induced pluripotent stem cells to primary immunodeficiency diseases. (2019) (7)
Response to Comment on “Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells” (2013) (6)
Structural and spatial chromatin features at developmental gene loci in human pluripotent stem cells (2017) (6)
Aging and CMV Infection Affect Pre-existing SARS-CoV-2-Reactive CD8+ T Cells in Unexposed Individuals (2021) (6)
Screening of Human cDNA Library Reveals Two differentiation‐Related Genes, HHEX and HLX, as Promoters of Early Phase Reprogramming toward Pluripotency (2016) (6)
Corrigendum: Harmonizing standards for producing clinical-grade therapies from pluripotent stem cells (2014) (6)
10 Questions: Clinical Outlook for iPSCs. (2016) (5)
A New High-Resolution Printer for Digitally Synthetic Holograms (2004) (5)
Generation of high quality iPS cells (2007) (5)
Implantation-Competent Blastocyst-Like Structures from Mouse Pluripotent Stem Cells (2018) (5)
An emerging strategy of gene therapy for cardiac disease. (2012) (5)
[Molecular mechanisms underlying pluripotency of embryonic stem cells]. (2006) (4)
Shinya Yamanaka (2010) (4)
[Derivation of engraftable myogenic precursors from murine ES/iPS cells and generation of disease-specific iPS cells from patients with Duchenne muscular dystrophy (DMD) and other diseases]. (2010) (4)
" Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells " ( 2007 ) , by Junying Yu (2017) (4)
Mathematical Modeling of Planar Cell Polarity To (2008) (4)
iPS Cells 10 Years Later (2016) (4)
A novel therapeutic strategy for midfacial hypoplasia using the CNP/GC-B system ☆ (2017) (4)
シンポジウム07―3 再生医学研究最前線（日本神経化学会との共同開催） Derivation of Engraftable Myogenic Precursors from Murine ES/iPS cells and Generation of Disease-specific iPS cells from Patients with Duchenne Muscular dystrophy (DMD) and Other Diseases (2010) (4)
Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I. (2019) (3)
Function of Myc for Generation of Induced Pluripotent Stem Cells (2012) (3)
[Research for cell therapy by induced pluripotent stem cell]. (2011) (3)
Thermal Conductivity of Carbon Nanotube/Copper Composites Fabricated by Colloidal Process (2008) (2)
Foramen magnum stenosis and midface hypoplasia in C-type natriuretic peptide-deficient rats and restoration by the administration of human C-type natriuretic peptide with 53 amino acids (2019) (2)
Induced pluripotent stem cell technology: venturing into the second decade (2020) (2)
Title Precise correction of the dystrophin gene in duchenne muscular dystrophy patient induced pluripotent stem cells by TALEN and CRISPR-Cas 9 (2018) (2)
Evaluation of safety of induced pluripotent stem cells by genome integrity (2014) (2)
Abstract 2965: Cardiomyocyte Sheets Derived From Induced Pluripotent Stem (iPS) Cells Improve Cardiac Function and Attenuate Cardiac Remodeling in Myocardial Infarction in Mice (2009) (2)
Abstract 16184: Single Cell RNA Sequencing Reveals Dynamic and Heterogeneous Changes of Transcriptome During Cardiac Differentiation in vitro (2014) (2)
Naohiro Egawa Cells Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem (2012) (2)
Generation of disease-specific induced pluripotent stem cells from Alzheimer's disease patients (2010) (2)
Establishment of mouse induced pluripotent stem cells selected for Nanog expression (2008) (2)
The Winding Road to Pluripotency (2014) (2)
Chapter 18 – Induced Pluripotent Stem Cells (2013) (2)
The nomenclature system should be sustainable, but also practical. (2011) (2)
Generation of Retinal Progenitor Cells From Human Induced Pluripotent Stem Cells (2009) (2)
Expression dynamics of HAND1/2 in in vitro human cardiomyocyte differentiation (2021) (2)
Generation of Blood Cells from Human Ips Cells in Vitro through the Hematopoietic Progenitors Concentrated within the Unique Structures, Ips-Sac. (2008) (1)
Recent advance in induced pluripotent stem cells (2008) (1)
Title Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient iPS Cells by TALEN and (2016) (1)
The subcommissural organ maintains features of neuroepithelial cells in the adult mouse (2022) (1)
Generation of disease-specific induced pluripotent stem cells from sporadic Parkinson's disease patients (2011) (1)
Reconstruction of Nuclear Reprogramming by Defined Factors (2009) (1)
Improved Sendai viral system for reprogramming to naive pluripotency (2022) (1)
and of Using (2017) (1)
Stem Cells in Translation (2013) (1)
Young Researchers in Japan (2013) (1)
Transplantation of human iPS cell-derived neurospheres for the treatment of spinal cord injury in NOD-scid mice (2010) (1)
Title ECAT 11 / L 1 td 1 is enriched in ESCs and rapidly activated during iPSC generation , but it is dispensable for the maintenance and induction of pluripotency (2017) (1)
Induced Pluripotent Stem Cells [1] (2019) (1)
Cancellation of c-MYC Silencing in Human Induced Pluripotent Stem Cells Contributes to the Efficient in Vitro Production of Platelets with the Ability of Hemostasis In Vivo. (2009) (1)
Multi-omics approach reveals posttranscriptionally regulated genes are essential for human pluripotent stem cells (2022) (1)
, Satoshi Pluripotent Stem Cells Directed and Systematic Differentiation of Cardiovascular Cells From Mouse Induced (2008) (1)
Introduction: Guest Editor: Shinya Yamanaka (2008) (1)
The 2012 Nobel Prize in Physiology or (2013) (1)
When Myc's asleep, embryonic stem cells are dormant (2016) (1)
Chapter 26 – Induced Pluripotent Stem Cells (2014) (1)
A case of gas gangrene in the head and neck progressing to descending necrotizing mediastinitis (2016) (1)
A case of peripheral ameloblastoma that developed in the maxillary gingiva of child (2020) (1)
Association of Education and Depressive Symptoms with Tooth Loss (2020) (1)
A case of oral lichenoid reaction during nivolumab therapy (2020) (1)
Disease Modeling and Drug Discovery Using Induced Pluripotent Stem Cells From CINCA Syndrome Patients (2012) (0)
Title MHC matching improves engraftment of iPSC-derived neurons in non-human primates (2018) (0)
An interview with... Shinya Yamanaka. Interview by Mary Muers. (2010) (0)
Risk analysis for Boston lab slammed as 'shoddy' (2007) (0)
Induction of astrocyte differentiation from human induced pluripotent stem cells carrying mutant SOD1 (2011) (0)
PE-454 Cell Line-dependent Differentiation of Mouse Induced-pluripotent Stem Cells into Cardiomyocytes(PE076,Regeneration (M),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society) (2009) (0)
Faculty Opinions recommendation of Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. (2007) (0)
AIDS worker's misconduct ban belatedly comes to light (2007) (0)
MOLECULAR SIGNATURES AND MECHANISMS OF HUMAN GERMLINE DEVELOPMENT IN VIVO Regulations on the Study of Human Germline Development (2012) (0)
Methods for Evaluating Human Induced Pluripotent Stem Cells (2012) (0)
Endangered species cling on as rulings are overturned (2007) (0)
A clinical-grade HLA haplobank of human induced pluripotent stem cells matching approximately 40% of the Japanese population. (2022) (0)
A New Path: Induced Pluripotent Stem Cells (2009) (0)
iPS cell differentiation (2018) (0)
Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Maturation Defect of Myelodysplastic Syndromes (2014) (0)
The iPS Breakthrough Paper (2014) (0)
Evaluation of human iPS cells by neural differentiation and tumorigenicity (2011) (0)
Recent progress in iPS cell research and application (2017) (0)
[Possibility of iPS cells (discussion)]. (2009) (0)
A stress-reduced passaging technique improves the viability of human pluripotent cells (2021) (0)
A Cell-ebration of Induced Pluripotency. (2016) (0)
Generation of induced pluripotent stem cells from a familial Alzheimer's disease patient (2011) (0)
Abstract 3227: Molecular Characterization of Induced Pluripotent Stem (iPS) Cell-Derived Cardiomyocytes (2009) (0)
Differentiation of induced pluripotent stem cells from ALS patients generates motor neurons (2010) (0)
Title Patient-specific human induced pluripotent stem cell model assessed with electrical pacing validates S107 as a potential therapeutic agent for catecholaminergic polymorphic ventricular tachycardia (2018) (0)
OP73 A SMALL MOLECULE THAT FACILITATES THE DIFFERENTIATION INTO PANCREATIC ENDOCRINE CELLS FROM HUMAN ES/IPS CELLS (2014) (0)
SUN-313 A NEW NEPHRON PROGENITOR CELL REPLACEMENT SYSTEM CAN REGENERATE NEPHRONS FROM HUMAN INDUCED PLURIPOTENT STEM CELLS (2020) (0)
Abstract 15113: A Novel Purification Method for Cardiomyocytes and Endothelial Cells Derived From Human Pluripotent Stem Cells Using Microrna-responsive Messenger Rna (2014) (0)
A Cell-ebration of Induced Pluripotency (2016) (0)
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007 [ 1 ] (2019) (0)
Human Induced Pluripotent Stem Cell Generation: Conventional Method (2012) (0)
" Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins " ( 2009 ) , by Hongyan Zhou (2018) (0)
Title Structural and spatial chromatin features at developmental geneloci in human pluripotent stem cells (2019) (0)
Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts " ( 2007 ) , by Masato (2019) (0)
Safer way to make human stem-like cells revealed (2007) (0)
Chapter 13 – Induced Pluripotent Stem Cells (2011) (0)
Understanding Intracellular Signaling Advances Cardiac Reprogramming Technology Toward Clinical Applications. (2016) (0)
"Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins" (2009), by Hongyan Zhou et al (2018) (0)
Comprehensive Comparison Of Gene Expression, Genomic DNA Methylation, and In Vitro Hematopoietic Differentiation Among Many Human iPS and ES Cell Lines (2013) (0)
Base-resolution methylome analysis of the retinal pigment epithelium used in the first case of patient-derived induced pluripotent stem cell-based autologous transplantation (2016) (0)
model for dissecting somatic mosaicism and drug discovery Induced pluripotent stem cells from CINCA syndrome patients as a (2013) (0)
Ethics and Induced Pluripotent Stem Cells [1] (2019) (0)
Mouse Molecular Genetics Symposium : Upstream and downstream regulators of Nanog and ERas, two important molecules in ES cell biology (2004) (0)
Shinya Yamanaka: purveyor of pluripotency. Interview by Ruth Williams. (2013) (0)
Neurodegenerative disease-specific induced pluripotent Stem cells research (2009) (0)
1. Possibility of IPS Cells (-induced Pluripotent Stem Cell) and Its Challenge (2009) (0)
Title Rats deficient C-type natriuretic peptide suffer from impairedskeletal growth without early death (2018) (0)
P-151 Trichostatin A, an HDAC Inhibitor, Induces Differentiation of Induced Pluripotent Stem Cells into Cardiomyocytes in Mice (2009) (0)
[RNA editing]. (1997) (0)
Nuclear Reprogramming without Embryos (2006) (0)
Abstract 10103: Cell Cycle Activation of Hypertrophic Cardiomyopathy: Insights From Research of Patient-Specific Induced Pluripotent Stem Cells-Derived Cardiomyocytes (2013) (0)
Resource Efficient Detection and Pu rification of Cell Populations Using Synthetic MicroRNA Switches Graphical (2015) (0)
CRISPRi mediated Down regulation of SFPQ Gene Expression in Human induced Pluripotent Stem Cells Results in Massive Cell Death (2021) (0)
In This Issue (2007) (0)
Title A study on ensuring the quality and safety of pharmaceuticals and medical devices derived from processing of allogeneic human induced pluripotent stem (-Like ) cells (2018) (0)
Abstract 12431: Analysis of Cardiomyocytes Differentiated from Disease-Specific Induced Pluripotent Stem Cells in Lamin A/C-related Cardiomyopathy (2011) (0)
Analysis of Clone Structure of iPSCs Using Whole Genome Sequencing (2016) (0)
The mechanism of post-transcriptional control in human induced pluripotent stem cells by analyses of global transcriptome and proteome data (2015) (0)
Analyzing the Stepwise Developmental Pathway From ES/IPS Cells to Functional Mature Erythrocytes. (2009) (0)
Erratum for DOI: 10.31662/jmaj.2018-0005 (2018) (0)
Factor 4 E-Binding Proteins Amino Acids and Insulin on Initiation mTOR Cooperate To Mediate the Effects of Distinct Signaling Events Downstream of (2005) (0)
Abstract 17537: Stably Expressed APEX2 Identifies the Integration of iPSC-derived Cardiomyocytes in a Mouse Model of Myocardial Infarction (2015) (0)
[Mechanism for maintaining pluripotency in embryonic stem cells and inner cell mass]. (2005) (0)
HLA 6 loci matched allogeneic iPS cells derived retinal pigment epithelial cells (iPSC-RPE) transplantation (2019) (0)
Aoi Stomach Cells Generation of Pluripotent Stem Cells from Adult Mouse Liver and (2012) (0)
"Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts" (2007), by Masato Nakagawa et al (2017) (0)
Title A novel efficient feeder-free culture system for the derivationof human induced pluripotent stem cells (2017) (0)
Cell reprogramming factor. (2006) (0)
Symposium: Nuclear reprogramming and the control of differentiation in mammalian embryos. Introduction. (2008) (0)
Ethics and Induced Pluripotent Stem Cells [1] (2022) (0)
" Generation of Induced Pluripotent Stem Cells without Myc from Mouse and Human Fibroblasts " ( 2007 ) (2018) (0)
Induced Pluripotent Stem Cell Experiments by Kazutoshi Takahashi and Shinya Yamanaka in 2006 and 2007 (2018) (0)
Post-transcriptionally regulated genes are essential for pluripotent stem cell survival (2021) (0)
Applications for the Use of Induced Pluripotent Stem Cells and Related Concerns: An Overview Steps Toward Safe Cell Therapy Using Induced Pluripotent Stem Cells Steps Toward Safe Cell Therapy Using Induced (2013) (0)
Title iPS cells : A source of cardiac regeneration (2017) (0)
Abstract 18307: T-tubules and Dyad Formation in Engrafted iPSC-Derived Cardiomyocytes With Stable APEX2 Expression (2016) (0)
Title Global Splicing Pattern Reversion during Somatic CellReprogramming (2017) (0)
Integration-Free Method for the Generation of Human Induced Pluripotent Stem Cells (2012) (0)
Metal compound of the aromatic hydroxycarboxylic acid charge control agent, toner and powder dye (1996) (0)
Title Induced pluripotent stem cells : opportunities and challenges (2017) (0)
Synthesis and Physical Properties of Yb1+xIn1-xCu4 -Two-step Magnetic Anomaly in the High Field Magnetization Process- (2020) (0)
Phase difference film layered body having layer with specified ratio of polyphenylene ether to polystyrene-based polymer and method for producing the same (2013) (0)
" Alternative Sources of Human Pluripotent Stem Cells " ( 2005 ) , by Leon Kass and the President ? s Council on Bioethics (2018) (0)
Temperature and Pressure Dependences of the Electronic and Crystal Structures of Yb4TGe8 (T = Cr, Mn, Fe, Co, and Ni) Studied by High-resolution X-ray Absorption Spectroscopy, X-ray Diffraction, and Photoelectron Spectroscopy (2022) (0)
Establishment of iPS cells from amyotrophic lateral sclerosis model mice (2010) (0)
Research for the quantum critical point of CeAg x Cu 1-x Sb 2 (2020) (0)
Generation of disease-specific induced pluripotent stem cells from hereditary Parkinson’s disease (2010) (0)
Shinya Yamanaka (1962- ) (2018) (0)
Establishment of iPS cells from amyotrophic lateral sclerosis model mice and motor neuronal differentiation (2011) (0)
Low temperature physical properties of layered compounds T x TaS 2 ( T :3d transition metal) (2019) (0)
Establishment and characterization of iPS cells derived from XPA patients (2016) (0)
Valence Transitions in Yb1+xIn1−xCu4 Studied by High-resolution X-ray Absorption Spectroscopy, X-ray Diffraction, and Photoelectron Spectroscopy (2022) (0)
Anomalous low-temperature physical properties of the ytterbium-based Kondo-lattice compounds <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msub><mml:mi>Yb</mml:mi><mml:mn>4</mml:mn></mml:msub><mml:mi>T</mml:mi><mml:msub><mml:mi>Ge</mml:mi><mml:mn>8</mml:mn></mml:msub></mml (2022) (0)
A kinetic model for isothermal coverage oscillations of charged species on film surfaces (1984) (0)
New Era of Medicine with iPS Cells (2018) (0)
Various magnetic structures in layered compounds M x TX 2 ( M = Cr, Co, Ni, T = Nb, Ta, X = S, Se) (2020) (0)
Charge control agent, production method and toner for developing electrostatic images (2000) (0)
Abstract 17534: The Most Appropriate Number of Personnel Needed for Chest Compressions for In-hospital Cardiac Arrest: A Randomized, Crossover Manikin Study (2015) (0)
Abstract IA12: Induction of pluripotency by defined factors (2011) (0)
1 iPS cells : A source of cardiac regeneration (2016) (0)
Methode de reprogrammation nucleaire (2008) (0)
Konnichiwa: Japanese scientists and their struggle to speak English (2021) (0)
Current status of X-ray imaging using synchrotron radiation PARP1 regulates cellular processes mediated by exosomal miRNAs in dental pulp stem cells The 30th Annual Meeting of the Society for Hard Tissue Regenerative Biology Period: August 26-27, 2022 (2022) (0)
Generation of Retinal Progenitor Cells From Induced Pluripotent Stem (iPS) Cells (2008) (0)
Periodontal Tissue as a Biomaterial for Hard-Tissue Regeneration following bmp-2 Gene Transfer (2022) (0)
OE-251 Molecular Characterization, Safety and Feasibility of Induced Pluripotent Stem (iPS) Cell-derived Cardiomyocytes for Heart Regenerative Therapy(OE43,Regeneration (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society) (2009) (0)
Nonexposed antiresorptive agent-related osteomyelitis of the jaw: a single-center cohort study (2022) (0)
Association between tooth loss and longitudinal changes in B-type natriuretic peptide over 5 years in postmenopausal women: the Nagahama Study. (2021) (0)
Faculty Opinions recommendation of FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. (2007) (0)
Effect of C-type natriuretic peptide on craniofacial skeletogenesis in mice during the pubertal growth spurt. (2022) (0)
Circulatory C-type natriuretic peptide reduces mucopolysaccharidosis-associated craniofacial hypoplasia in vivo (2022) (0)
Naoki Nagata and Shinya Yamanaka Physiology Involved in Somatic Mosaicism Perspectives for Induced Pluripotent Stem Cell Technology : New Insights Into Human (2014) (0)
Abstract 15182: Imaging iPSC-Derived Cardiomyocytes Engrafted in a Mouse Model of Myocardial Infarction Using Stably Expressed APEX2 (2017) (0)
Abstract 11156: Very High Engraftment, Proliferation, and Therapeutic Potential of IPSC-Derived Cardiomycytes (2014) (0)
John Bertrand Gurdon (1933- ) [1] (2022) (0)
[Signaling maintaining pluripotency in ES cells]. (2004) (0)
Ips Technology Revealed the Genetic and Functional Diversity Present in a Secondary AML Patient (2016) (0)
Title Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells (2018) (0)
Abstract 3871: Inhibition of Histone Deacetylation Markedly Induces Myocardial Differentiation of Induced Pluripotent Stem Cells in Mice (2009) (0)

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