Anindya Dutta
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Indian-born American biochemist and cancer researcher
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Anindya Dutta's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry Delhi University
Why Is Anindya Dutta Influential?
(Suggest an Edit or Addition)According to Wikipedia, Anindya Dutta is an Indian-born American biochemist and cancer researcher, a Chair of the Department of Genetics at the University of Alabama at Birmingham School of Medicine since 2021, who has served as Chair of the Department of Biochemistry and Molecular Genetics at the University of Virginia School of Medicine in 2011–2021. Dutta's research has focused on the mammalian cell cycle with an emphasis on DNA replication and repair and on noncoding RNAs. He is particularly interested in how de-regulation of these processes promote cancer progression. For his accomplishments he has been elected a Fellow of the American Association for the Advancement of Science, received the Ranbaxy Award in Biomedical Sciences, the Outstanding Investigator Award from the American Society for Investigative Pathology, the Distinguished Scientist Award from the University of Virginia and the Mark Brothers Award from the Indiana University School of Medicine.
Anindya Dutta's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (2007) (5196)
- p21 in cancer: intricate networks and multiple activities (2009) (2278)
- DNA replication in eukaryotic cells. (2002) (2197)
- The ENCODE (ENCyclopedia Of DNA Elements) Project (2004) (2194)
- The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. (2007) (1235)
- A novel class of small RNAs: tRNA-derived RNA fragments (tRFs). (2009) (902)
- Muscle-specific microRNA miR-206 promotes muscle differentiation (2006) (779)
- MicroRNAs in cancer. (2009) (735)
- Preventing re-replication of chromosomal DNA (2005) (697)
- Inhibition of eukaryotic DNA replication by geminin binding to Cdt1. (2000) (633)
- Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA (1995) (617)
- Small RNAs with Imperfect Match to Endogenous mRNA Repress Translation (2003) (452)
- The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration (2014) (433)
- Initiation of DNA replication in eukaryotic cells. (1997) (412)
- A p53-dependent checkpoint pathway prevents rereplication. (2003) (410)
- Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets (2014) (395)
- Inhibition of DNA replication factor RPA by p53 (1993) (372)
- Depletion of Human Micro-RNA miR-125b Reveals That It Is Critical for the Proliferation of Differentiated Cells but Not for the Down-regulation of Putative Targets during Differentiation* (2005) (362)
- PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. (2008) (361)
- Cyclin-binding motifs are essential for the function of p21CIP1 (1996) (359)
- miR-206 and -486 Induce Myoblast Differentiation by Downregulating Pax7 (2010) (336)
- Biogenesis and Function of Transfer RNA-Related Fragments (tRFs). (2016) (306)
- Right Place, Right Time, and Only Once: Replication Initiation in Metazoans (2005) (306)
- Replication from oriP of Epstein-Barr Virus Requires Human ORC and Is Inhibited by Geminin (2001) (292)
- Long non-coding RNAs as emerging regulators of differentiation, development, and disease (2014) (287)
- Human CDC6/Cdc18 Associates with Orc1 and Cyclin-cdk and Is Selectively Eliminated from the Nucleus at the Onset of S Phase (1998) (280)
- PCNA Is a Cofactor for Cdt1 Degradation by CUL4/DDB1-mediated N-terminal Ubiquitination* (2006) (274)
- UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. (2006) (268)
- NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells. (2010) (263)
- cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication. (1992) (262)
- Rereplication by Depletion of Geminin Is Seen Regardless of p53 Status and Activates a G2/M Checkpoint (2004) (255)
- CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation. (2010) (251)
- The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1* (2009) (250)
- miR-99 family of MicroRNAs suppresses the expression of prostate-specific antigen and prostate cancer cell proliferation. (2011) (223)
- Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1. (2006) (218)
- RVB1/RVB2: running rings around molecular biology. (2009) (217)
- tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner (2018) (213)
- Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. (2004) (213)
- DNA replication and progression through S phase (2005) (207)
- The APC/C inhibitor, Emi1, is essential for prevention of rereplication. (2007) (203)
- Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein–Barr virus (2001) (201)
- Xenopus Mcm10 binds to origins of DNA replication after Mcm2-7 and stimulates origin binding of Cdc45. (2002) (200)
- tRFdb: a database for transfer RNA fragments (2014) (193)
- Mcm10 and And-1/CTF4 recruit DNA polymerase α to chromatin for initiation of DNA replication (2007) (192)
- MiR-322/424 and -503 Are Induced during Muscle Differentiation and Promote Cell Cycle Quiescence and Differentiation by Down-Regulation of Cdc25A (2010) (192)
- Extrachromosomal MicroDNAs and Chromosomal Microdeletions in Normal Tissues (2012) (189)
- miR-26a is required for skeletal muscle differentiation and regeneration in mice. (2012) (186)
- Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection (2010) (182)
- Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer. (1995) (171)
- Human Rvb1/Tip49 Is Required for the Histone Acetyltransferase Activity of Tip60/NuA4 and for the Downregulation of Phosphorylation on H2AX after DNA Damage (2008) (163)
- MicroRNA-378 Targets the Myogenic Repressor MyoR during Myoblast Differentiation* (2011) (155)
- The Evolutionarily Conserved Zinc Finger Motif in the Largest Subunit of Human Replication Protein A Is Required for DNA Replication and Mismatch Repair but Not for Nucleotide Excision Repair* (1998) (151)
- CRL4(Cdt2) E3 ubiquitin ligase monoubiquitinates PCNA to promote translesion DNA synthesis. (2010) (149)
- An Eukaryotic RuvB-like Protein (RUVBL1) Essential for Growth* (1998) (146)
- A Bipartite Substrate Recognition Motif for Cyclin-dependent Kinases* (2001) (134)
- Differential efficacy of 3-hydroxy-3-methylglutaryl CoA reductase inhibitors on the cell cycle of prostate cancer cells (2006) (132)
- Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathway. (2010) (131)
- Degradation of Cdt1 during S Phase Is Skp2-independent and Is Required for Efficient Progression of Mammalian Cells through S Phase* (2005) (131)
- The miR-99 family regulates the DNA damage response through its target SNF2H (2012) (131)
- p21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complex. (1996) (130)
- Normal and Cancerous Tissues Release Extrachromosomal Circular DNA (eccDNA) into the Circulation (2017) (129)
- Mechanisms to control rereplication and implications for cancer. (2007) (126)
- Mcm10 and And-1/CTF4 recruit DNA polymerase alpha to chromatin for initiation of DNA replication. (2007) (124)
- MUNC, a Long Noncoding RNA That Facilitates the Function of MyoD in Skeletal Myogenesis (2014) (121)
- Temporal profile of replication of human chromosomes. (2005) (119)
- Pan-S replication patterns and chromosomal domains defined by genome-tiling arrays of ENCODE genomic areas. (2007) (119)
- CRL4Cdt2: master coordinator of cell cycle progression and genome stability. (2011) (117)
- latheo Encodes a Subunit of the Origin Recognition Complex and Disrupts Neuronal Proliferation and Adult Olfactory Memory When Mutant (1999) (117)
- Expression of geminin as a marker of cell proliferation in normal tissues and malignancies. (2002) (116)
- Rvb1p and Rvb2p Are Essential Components of a Chromatin Remodeling Complex That Regulates Transcription of over 5% of Yeast Genes* (2001) (116)
- p130‐Angiomotin associates to actin and controls endothelial cell shape (2006) (112)
- Architecture of the Human Origin Recognition Complex* (2001) (112)
- Discoveries of Extrachromosomal Circles of DNA in Normal and Tumor Cells. (2018) (108)
- p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases (1997) (107)
- The lncRNA DRAIC/PCAT29 Locus Constitutes a Tumor-Suppressive Nexus (2015) (102)
- The role of microRNAs in glioma initiation and progression. (2012) (102)
- Geminin-Cdt1 balance is critical for genetic stability. (2005) (100)
- An ATR- and BRCA1-Mediated Fanconi Anemia Pathway Is Required for Activating the G2/M Checkpoint and DNA Damage Repair upon Rereplication (2006) (99)
- MicroRNAs: small but potent oncogenes or tumor suppressors. (2006) (98)
- Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells (2013) (98)
- Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity. (2015) (96)
- Genomic instability in cancer. (2013) (95)
- The MCM8-MCM9 Complex Promotes RAD51 Recruitment at DNA Damage Sites To Facilitate Homologous Recombination (2013) (93)
- The Origin Recognition Complex Localizes to Telomere Repeats and Prevents Telomere-Circle Formation (2007) (93)
- Multiple Mechanisms Regulate Subcellular Localization of Human CDC6* (2001) (93)
- UBE2T, the Fanconi Anemia Core Complex, and FANCD2 Are Recruited Independently to Chromatin: a Basis for the Regulation of FANCD2 Monoubiquitination (2007) (93)
- Novel Anti-Apoptotic MicroRNAs 582-5p and 363 Promote Human Glioblastoma Stem Cell Survival via Direct Inhibition of Caspase 3, Caspase 9, and Bim (2014) (92)
- Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription. (2011) (92)
- Acute Reduction of an Origin Recognition Complex (ORC) Subunit in Human Cells Reveals a Requirement of ORC for Cdk2 Activation* (2005) (88)
- p21-dependent Inhibition of Colon Cancer Cell Growth by Mevastatin Is Independent of Inhibition of G1 Cyclin-dependent Kinases* (2003) (87)
- A 39 amino acid fragment of the cell cycle regulator p21 is sufficient to bind PCNA and partially inhibit DNA replication in vivo. (1996) (86)
- Notch3 and Mef2c Proteins Are Mutually Antagonistic via Mkp1 Protein and miR-1/206 MicroRNAs in Differentiating Myoblasts* (2012) (83)
- Dissection of Functional Domains of the Human DNA Replication Protein Complex Replication Protein A* (1996) (83)
- A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition. (2004) (83)
- Noncanonical Roles of tRNAs: tRNA Fragments and Beyond. (2020) (81)
- Mutational Analysis of the Cy Motif from p21 Reveals Sequence Degeneracy and Specificity for Different Cyclin-Dependent Kinases (2001) (81)
- Recruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cells. (2005) (80)
- Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. (2008) (79)
- ORC5L, a New Member of the Human Origin Recognition Complex, Is Deleted in Uterine Leiomyomas and Malignant Myeloid Diseases* (1998) (79)
- A New lncRNA, APTR, Associates with and Represses the CDKN1A/p21 Promoter by Recruiting Polycomb Proteins (2014) (78)
- Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing (2019) (77)
- Deubiquitination of Tip60 by USP7 Determines the Activity of the p53-Dependent Apoptotic Pathway (2013) (77)
- The effect of the intra-S-phase checkpoint on origins of replication in human cells. (2011) (75)
- Identification of HsORC4, a Member of the Human Origin of Replication Recognition Complex* (1997) (75)
- Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis (2016) (75)
- Identification and Characterization of the Human ORC6 Homolog* (2000) (75)
- Molecular requirements for transformation of fallopian tube epithelial cells into serous carcinoma. (2011) (72)
- CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration. (2013) (70)
- Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma (2014) (68)
- MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex (2015) (68)
- The Human Homolog of Saccharomyces cerevisiae CDC45 * (1998) (68)
- BH‐protocadherin‐c, a member of the cadherin superfamily, interacts with protein phosphatase 1 alpha through its intracellular domain (1999) (64)
- Identification and characterization of extrachromosomal circular DNA in maternal plasma (2020) (64)
- ATR Pathway Is the Primary Pathway for Activating G2/M Checkpoint Induction After Re-replication* (2007) (63)
- ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines (2020) (63)
- The Emergence of the Conserved AAA+ ATPases Pontin and Reptin on the Signaling Landscape (2013) (62)
- Tip60 Degradation by Adenovirus Relieves Transcriptional Repression of Viral Transcriptional Activator EIA (2012) (61)
- The SKP1-Cul1-F-box and Leucine-rich Repeat Protein 4 (SCF-FbxL4) Ubiquitin Ligase Regulates Lysine Demethylase 4A (KDM4A)/Jumonji Domain-containing 2A (JMJD2A) Protein* (2011) (60)
- Inhibition of cdk2 Activating Phosphorylation by Mevastatin* (2003) (60)
- A Prognostic Signature for Lower Grade Gliomas Based on Expression of Long Non-Coding RNAs (2018) (60)
- Phosphorylation of human replication protein A by the DNA-dependent protein kinase is involved in the modulation of DNA replication. (1996) (59)
- Overcoming Platinum Resistance in Preclinical Models of Ovarian Cancer Using the Neddylation Inhibitor MLN4924 (2013) (58)
- Defective nuclear import of Tpr in Progeria reflects the Ran sensitivity of large cargo transport (2013) (55)
- Small extrachromosomal circular DNAs, microDNA, produce short regulatory RNAs that suppress gene expression independent of canonical promoters (2019) (54)
- Rpa4, a homolog of the 34-kilodalton subunit of the replication protein A complex (1995) (54)
- Subsets of Human Origin Recognition Complex (ORC) Subunits Are Expressed in Non-proliferating Cells and Associate with Non-ORC Proteins* (2000) (48)
- In vivo cyclin E expression as a marker for early cervical neoplasia. (1998) (47)
- CRL4Cdt2 E3 Ubiquitin Ligase and Proliferating Cell Nuclear Antigen (PCNA) Cooperate to Degrade Thymine DNA Glycosylase in S Phase* (2014) (47)
- Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4Cdt2 Ubiquitin Ligase Complex (2011) (46)
- DNA replication and the cell cycle. (1992) (45)
- APC/C – the master controller of origin licensing? (2007) (44)
- RVBs Are Required for Assembling a Functional TIP60 Complex (2013) (44)
- Sequential replication-coupled destruction at G1/S ensures genome stability (2015) (44)
- The Acetyltransferase Tip60 Is a Critical Regulator of the Differentiation-Dependent Amplification of Human Papillomaviruses (2015) (42)
- The Immortal Strand Hypothesis: How Could It Work? (2008) (42)
- The destruction box of human Geminin is critical for proliferation and tumor growth in human colon cancer cells (2004) (41)
- Requirement of CDC45 for Postimplantation Mouse Development (2001) (40)
- Supplemental Data Rvb 1 p / Rvb 2 p Recruit Arp 5 p and Assemble a Functional Ino 80 Chromatin Remodeling Complex (40)
- Autocatalytic Phosphorylation of CDK2 at the Activating Thr160 (2007) (40)
- The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors (2015) (39)
- The Evolution of Guanylyl Cyclases as Multidomain Proteins: Conserved Features of Kinase-Cyclase Domain Fusions (2009) (39)
- 14-3-3 Proteins Play a Role in the Cell Cycle by Shielding Cdt2 from Ubiquitin-Mediated Degradation (2014) (39)
- miR-206 and -486 Induce Myoblast Differentiation by Downregulating Pax7 (2011) (38)
- Human Cdt1 Lacking the Evolutionarily Conserved Region That Interacts with MCM2–7 Is Capable of Inducing Re-replication* (2008) (37)
- Cellular Checkpoint Mechanisms Monitoring Proper Initiation of DNA Replication* (2005) (37)
- Proliferating Human Cells Hypomorphic for Origin Recognition Complex 2 and Pre-replicative Complex Formation Have a Defect in p53 Activation and Cdk2 Kinase Activation* (2006) (35)
- Degradation of p12 Subunit by CRL4Cdt2 E3 Ligase Inhibits Fork Progression after DNA Damage* (2013) (35)
- Serum and v-src increase the level of a CCAAT-binding factor required for transcription from a retroviral long terminal repeat. (1990) (35)
- The Deubiquitinase USP46 Is Essential for Proliferation and Tumor Growth of HPV-Transformed Cancers. (2018) (34)
- LINC00152 Promotes Invasion through a 3′-Hairpin Structure and Associates with Prognosis in Glioblastoma (2018) (33)
- Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells (2020) (33)
- MicroRNAs regulate and provide robustness to the myogenic transcriptional network. (2012) (33)
- The metazoan origin recognition complex. (1999) (33)
- DNA replication and genomic instability. (2005) (30)
- Long noncoding RNA DRAIC inhibits prostate cancer progression by interacting with IKK to inhibit NF-κB activation. (2020) (30)
- A pan-cancer analysis of prognostic genes (2015) (30)
- Two subunits of human ORC are dispensable for DNA replication and proliferation (2016) (30)
- Evaluation of Cyclin Expression in Testicular Germ Cell Tumors: Cyclin E Correlates with Tumor Type, Advanced Clinical Stage, and Pulmonary Metastasis (2000) (30)
- Detection of DNA fusion junctions for BCR-ABL translocations by Anchored ChromPET (2010) (29)
- MUNC, an Enhancer RNA Upstream from the MYOD Gene, Induces a Subgroup of Myogenic Transcripts in trans Independently of MyoD (2018) (28)
- Cyclin A and MIB1 (Ki67) as markers of proliferative activity in primary renal neoplasms. (1998) (28)
- tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model (2019) (27)
- ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks. (2017) (27)
- Proteasome inhibitors alter the orderly progression of DNA synthesis during S-phase in HeLa cells and lead to rereplication of DNA. (2000) (25)
- Evaluation of EVI1 and EVI1s (Delta324) as potential therapeutic targets in ovarian cancer. (2010) (25)
- ATR checkpoint kinase and CRL1βTRCP collaborate to degrade ASF1a and thus repress genes overlapping with clusters of stalled replication forks (2014) (25)
- Partial nucleotide sequence of Rous sarcoma virus-29 provides evidence that the original Rous sarcoma virus was replication defective (1985) (25)
- Loss of transactivation and transrepression function, and not RPA binding, alters growth suppression by p53. (1996) (24)
- Nuclear Scaffold Attachment Sites within ENCODE Regions Associate with Actively Transcribed Genes (2011) (24)
- 3 Assembly of Pre-replication Complexes (2006) (23)
- MicroRNAs induced in melanoma treated with combination targeted therapy of Temsirolimus and Bevacizumab (2013) (23)
- Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2 (2013) (22)
- DNA Replication: Mammalian Treslin–TopBP1 Interaction Mirrors Yeast Sld3–Dpb11 (2011) (22)
- Phosphorylation of replication protein A: a role for cdc2 kinase in G1/S regulation. (1991) (21)
- Noncoding RNAs in Glioblastoma (2017) (21)
- Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPK 2 but not AMPK 1 (2006) (21)
- Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPK (cid:1) 2 but not AMPK (cid:1) 1 (2006) (19)
- Chromosomal structural variations during progression of a prostate epithelial cell line to a malignant metastatic state inactivate the NF2, NIPSNAP1, UGT2B17, and LPIN2 genes (2013) (18)
- Site-specific amino acid substitution in dodecameric peptides determines the stability and unfolding of c-MYC quadruplex promoting apoptosis in cancer cells (2018) (18)
- Geminin and p53: Deterrents to Re-replication in Human Cancer Cells (2003) (18)
- CRL4Cdt2 (2011) (17)
- TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer (2022) (16)
- Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System. (2017) (16)
- The pan-cancer landscape of prognostic germline variants in 10,582 patients (2019) (16)
- Simultaneous mobility in MIPv6 (2005) (16)
- Targeted comparative RNA interference analysis reveals differential requirement of genes essential for cell proliferation. (2006) (15)
- Chaotic license for genetic instability and cancer (2007) (15)
- Master coordinator of cell cycle progression and genome stability (2011) (15)
- Activation of Fanconi Anemia Pathway in Cells with Re-Replicated DNA (2006) (14)
- Biological Processes Discovered by High-Throughput Sequencing. (2016) (14)
- Yeast genome analysis identifies chromosomal translocation, gene conversion events and several sites of Ty element insertion (2009) (13)
- Integrating QoS support in TeleMIP's mobility architecture (2000) (13)
- CIP 1 and Cdc 25 A : Competition between an Inhibitor and an Activator of Cyclin-Dependent Kinases (1997) (12)
- Microarray analysis of DNA replication timing. (2009) (12)
- Long noncoding RNAs in cancer immunity: a new avenue in drug discovery. (2020) (12)
- Erratum: A p53-dependent checkpoint pathway prevents rereplication (Molecular Cell (April 2003) 11 (997-1008)) (2003) (10)
- Low power frequeney-to-time conversion for cellular systems using predictive zero-crossing (1997) (10)
- Serum independence of transcription from the promoter of an avian retrovirus in v-src-transformed cells is a primary, intracellular effect of increased tyrosine phosphorylation. (1990) (9)
- Regulation of S phase. (2006) (9)
- MCM 8-9 complex promotes resection of double-strand break ends by MRE 11-RAD 50-NBS 1 complex (2015) (9)
- Non-micro-short RNAs: the new kids on the block (2012) (9)
- miR-206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro (2019) (9)
- A Prognostic Signature for Lower Grade Gliomas Based on Expression of Long Non-Coding RNAs (2018) (9)
- Distinct MUNC lncRNA structural domains regulate transcription of different promyogenic factors (2021) (8)
- A tumor suppressive long noncoding RNA, DRAIC, inhibits protein translation and induces autophagy by activating AMPK. (2021) (8)
- Human Primpol1: a novel guardian of stalled replication forks (2013) (8)
- Trans-plication factors? (1993) (8)
- What Is Extrachromosomal Circular DNA and What Does It Do? (2020) (8)
- The Germline Variants rs61757955 and rs34988193 Are Predictive of Survival in Lower Grade Glioma Patients (2019) (7)
- CDK2-Activating Kinase (CAK): More Questions than Answers (2006) (7)
- Germline Variants That Affect Tumor Progression. (2020) (6)
- Adaptive multiuser detector for asynchronous DS-CDMA in Rayleigh fading (1997) (6)
- p21 CIP1 and Cdc25A: Competition between an Inhibitor and an Activator of Cyclin-Dependent Kinases (1997) (6)
- A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins (2020) (5)
- MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage (2021) (5)
- ATAC-Seq-based Identification of Extrachromosomal Circular DNA in Mammalian Cells and Its Validation Using Inverse PCR and FISH. (2021) (5)
- Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A. (2021) (5)
- Faculty Opinions recommendation of Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing. (2010) (5)
- ATAC-seq identifies thousands of extrachromosomal circular DNA in cancers and cell lines (2019) (5)
- A human cancer cell line initiates DNA replication normally in the absence of ORC5 and ORC2 proteins (2020) (5)
- Dimerization ability, denaturation mechanism, and the stability of a staphylococcal phage repressor and its two domains. (2019) (4)
- A tumor suppressive long noncoding RNA, DRAIC, inhibits protein translation and induces autophagy by activating AMPK (2021) (4)
- miR‐206 family is important for mitochondrial and muscle function, but not essential for myogenesis in vitro (2020) (4)
- Promoter G-quadruplex favours epigenetic reprogramming-induced atypical expression of ZEB1 in cancer cells. (2021) (4)
- Comparison Between The Severity Of Atopic Dermatitis In Indian Children Born And Brought Up In UK And USA And That Of Indian Children Born And Brought UP In India (2003) (4)
- Germline variants predictive of tumor mutational burden and immune checkpoint inhibitor efficacy (2021) (4)
- Rad18 emerges as a critical regulator of the Fanconi anemia pathway (2011) (3)
- Processability and performance property correlation for LDPE/PA6-based nanocomposite and its monolayer blown film for packaging application (2022) (3)
- Function and Therapeutic Implications of tRNA Derived Small RNAs (2022) (3)
- Ruthenium-Benzothiadiazole Building Block Derived Dynamic Heterometallic Ru-Ag Coordination Polymer and Its Enhanced Water-Splitting Feature. (2021) (3)
- Global gene repression by Dicer-independent tRNA Fragments (2017) (2)
- EccDNA formation is dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA double-strand break (2020) (2)
- Extrachromosomal circular DNA, microDNA, without canonical promoters produce short regulatory RNAs that suppress gene expression (2019) (2)
- Short-term diet intervention alters the small non-coding RNA (sncRNA) landscape of human sperm (2021) (2)
- A Pro-metastatic tRNA Pathway (2016) (2)
- Immune response and possible therapeutics in COVID-19 (2020) (2)
- SV40-Based in Vitro DNA Replication Assay (1996) (1)
- Small Molecule Therapeutics Overcoming Platinum Resistance in Preclinical Models of Ovarian Cancer Using the Neddylation Inhibitor MLN 4924 (2013) (1)
- Initiation of replication in Xenopus egg extracts at a spatially defined origin (2015) (1)
- High energy proton implantation effect on the emission wavelength and strain phenomenon of strain coupled InAs/In(Ga)As submonolayer (SML) QDs and Stranski-Krastanov (SK) QDs (2022) (1)
- Aggregation induced enhanced emission in Dimethyl-2,5-bis(4-methoxyphenylamino)terephthalate (2020) (1)
- Continuous Ambulatory Peritoneal Dialysis Peritonitis Guidelines – Consensus Statement of Peritoneal Dialysis Society of India - 2020 (2021) (1)
- Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets (2014) (1)
- Expression of PACT and EIF2C2, Implicated in RNAi and MicroRNA pathways, in various human cell lines (2004) (1)
- The role of ANGIOGENIN, or lack thereof, in the generation of stress-induced tRNA halves and of smaller tRNA fragments that enter Argonaute complexes (2019) (1)
- The lncRNA DRAIC/PCAT29 Locus Constitutes a (2015) (1)
- The Germline Variants rs61757955 and rs34988193 are Predictive of Survival in Low Grade Glioma Patients (2018) (1)
- Modeling of early events in serous carcinogenesis: Molecular prerequisites for transformation of fallopian tube epithelial cells (2011) (1)
- Characteristic Analysis of Polarization and Dispersion Properties of PANDA Fiber Using Finite Element Methods (2007) (1)
- Nuclear localization of RFC40 by RIα: A link between cellular signaling and proliferation (2005) (1)
- Characterization of novel small non-coding RNAs and their modifications in bladder cancer using an updated small RNA-seq workflow (2022) (1)
- tRForest: a novel random forest-based algorithm for tRNA-derived fragment target prediction (2021) (1)
- MicroRNAs induced in melanoma treated with combination targeted therapy of Temsirolimus and Bevacizumab (2012) (1)
- De-stressing the T cells in need (2021) (1)
- The putative trans-activator in the MAgag region of Rous sarcoma virus is not required for cell transformation (1988) (1)
- FMRP directly interacts with R-loop and shows complex interplay with the DHX9 helicase (2022) (1)
- Re-replication 7 Is Capable of Inducing − MCM 2 Conserved Region That Interacts with Human Cdt 1 Lacking the Evolutionarily and Chromosome Dynamics : DNA : Replication , Repair (2008) (0)
- Faculty Opinions recommendation of Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses. (2013) (0)
- Abstract 3380: Overcoming platinum resistance in ovarian cancer using the novel compound MLN4924. (2013) (0)
- Author response: Two subunits of human ORC are dispensable for DNA replication and proliferation (2016) (0)
- Extraction of Human DNA Replication Timing Patterns from Discrete Microarray Data (2008) (0)
- Faculty Opinions recommendation of Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription. (2021) (0)
- Modeling optical second harmonic generation for oxide semiconductor interface characterization (2022) (0)
- Improved tensile and impact responses of microcellular PP/γ-irradiated elastomer blends corroborating microstructure and crystallinity (2021) (0)
- Regulation of S phase. (1998) (0)
- tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis (2022) (0)
- Faculty Opinions recommendation of Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins. (2016) (0)
- The correlator system for GMRT (1995) (0)
- MicroRNAs in control of cell proliferation (2008) (0)
- Identifying determinants of chromosomal domains as defined by time of replication (2009) (0)
- Efficient Search of Circular Repeats and MicroDNA Reintegration in DNA Sequences (2020) (0)
- Faculty Opinions recommendation of Structure and evolution of double minutes in diagnosis and relapse brain tumors. (2019) (0)
- Alternative Sigma Factor of Staphylococcus aureus Interacts with the Cognate Antisigma Factor Primarily Using Its Domain 3. (2021) (0)
- Faculty Opinions recommendation of Transcription shapes DNA replication initiation to preserve genome integrity. (2021) (0)
- HPVE6-USP46 Mediated Cdt2 Stabilization Reduces Set8 Mediated H4K20-Methylation to Induce Gene Expression Changes (2021) (0)
- XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis. (2023) (0)
- Faculty Opinions recommendation of eccDNAs are apoptotic products with high innate immunostimulatory activity. (2021) (0)
- Wireless-sensor-networks-based localization system for tracking positions in indoor systems. (2010) (0)
- Abstract 3174: Integrative analysis of genome-wide DNA replication origins in human cells (2023) (0)
- Figure 1, [miRNA biogenesis and functions. Black...]. (2017) (0)
- The pan-cancer landscape of prognostic germline variants in 10,582 patients (2020) (0)
- Faculty Opinions recommendation of Telomere repeat-binding factor 2 binds extensively to extra-telomeric G-quadruplexes and regulates the epigenetic status of several gene promoters. (2019) (0)
- regeneration and miR-675-5 p to promote skeletal muscle differentiation and long noncoding RNA gives rise to microRNAs miR-675-3 p H 19 The Material Supplemental (2014) (0)
- Development of Inhibitors That Selectively Disrupt Substrate Recognition by Cyclin-Dependent Kinases (2002) (0)
- Lipid Clustering in Mycobacterial Cell Envelope Layers Governs Spatially Resolved Solvation Dynamics. (2022) (0)
- Mapping Critical DNA Sequence Elements Required for Amplification of erbB2 in Breast Cancer (2002) (0)
- Faculty Opinions recommendation of Endoreduplication of the mouse genome in the absence of ORC1. (2018) (0)
- In Vitro Analysis of SV40 DNA Replication (1999) (0)
- SP-339-01: Performance-Based Seismic Design of the Tocumen Airport Terminal 2 (2020) (0)
- Transfer RNA Fragments (tRFs) , Novel MicroRNA‐like Short RNAs Generated independent of Dicer, Associate with Target mRNAs in Ago complexes and are De‐regulated in Many Cancers (2015) (0)
- Faculty Opinions recommendation of Replicative aging is associated with loss of genetic heterogeneity from extrachromosomal circular DNA in Saccharomyces cerevisiae. (2020) (0)
- Cryptic lncRNA-encoded ORFs: A hidden source of regulatory proteins (2023) (0)
- Identification and characterization of a flexile G-quadruplex in the distal promoter region of stemness gene REX1. (2023) (0)
- Action of the p53 Effector, p21, on its Targets: Cyclin-cdk and PCNA (2000) (0)
- Interaction of the Tumor Suppressor p53 with Replication Protein A. (1995) (0)
- Faculty Opinions recommendation of PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination. (2017) (0)
- Modified adaptive multiuser detector for DS-CDMA in multipath fading (1997) (0)
- MicroRNAs in Prostate Cancer (2008) (0)
- Integrated bioinformatic pipeline using whole-exome and RNAseq data to identify germline variants correlated with cancer (2022) (0)
- Structure‐Function Studies of MUNC LncRNA Reveal Domains Required for Its Promyogenic Phenotype (2021) (0)
- Wafl disrupts the recruitment of human Fenl by proliferating-cell nuclear antigen into the DNA replication complex ( cell cycle / maturation factor I / DNA repair ) (2005) (0)
- Faculty Opinions recommendation of Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. (2007) (0)
- Faculty Opinions recommendation of PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells. (2020) (0)
- Faculty Opinions recommendation of RNA promotes the formation of spatial compartments in the nucleus. (2021) (0)
- Faculty Opinions recommendation of Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional control over hCdt1. (2005) (0)
- Production of Extrachrom osomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity Graphical (2015) (0)
- Discovery and Development of Inhibitors that Selectively Interfere with Cyclin-Dependent Kinase Substrate Recognition (2005) (0)
- Title : Overcoming platinum resistance in preclinical models of ovarian cancer using the neddylation inhibitor MLN 4924 (2013) (0)
- Faculty Opinions recommendation of Homology explains the functional similarities of Treslin/Ticrr and Sld3. (2010) (0)
- Biochemical Analysis of RNA-DNA Hybrid and R-Loop Unwinding Via Motor Proteins. (2022) (0)
- Sequence driven interaction of amino acids in de-novo designed peptides determines c-Myc G-quadruplex unfolding inducing apoptosis in cancer cells. (2022) (0)
- Correction to: Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma (2018) (0)
- Transfer RNA Fragments (tRFs): a Novel Class of Non‐micro Short RNAs that Uses Ago1, 3 and 4 to Repress Specific Target RNAs Through 5′ Seed Sequences (2016) (0)
- Abstract 608: Oncogenic role of cullin 4 E3 ubiquitin ligase (CRL4-CDT2) in epithelial ovarian cancer (2011) (0)
- Editorial: The Role of RNA in Genome Stability: To Wreck or Repair? (2022) (0)
- Faculty Opinions recommendation of A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. (2007) (0)
- Identification of somatic mutations in uterine leiomyosarcomas (2015) (0)
- Functional TIP60 Complex RVBs Are Required for Assembling a (2014) (0)
- 1 Architecture of the Human Origin Recognition Complex (2001) (0)
- To Facilitate Homologous Recombination RAD51 Recruitment at DNA Damage Sites The MCM8-MCM9 Complex Promotes (2014) (0)
- Molecular Characterization of Extrachromosomal MicroDNAs in Human Cancer Cell Lines Using Synthetic Minicircles (2015) (0)
- Faculty Opinions recommendation of ATRX Promotes DNA Repair Synthesis and Sister Chromatid Exchange during Homologous Recombination. (2018) (0)
- The APC/C inhibitor, Emi1, is essential for prevention of re‐replication (2007) (0)
- Faculty Opinions recommendation of Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C. (2007) (0)
- Cellular Proteins Interacting with the Tumor Suppressor Protein p53. (1997) (0)
- Global Analysis of LncRNAs in Gliomas and Glioblastomas (2016) (0)
- Noncoding RNAs Regulating Differentiation and Cancer (2017) (0)
- Anindya Dutta (2015) (0)
- Abstract 5480: Expression and function of EVI1 and EVI1s (Δ324) ovarian cancer (2010) (0)
- Abstract 2396: Widespread occurrence of extrachromosomal microDNAs in normal and cancerous vertebrate tissues and cell lines (2014) (0)
- Faculty Opinions recommendation of Genomic analysis of circulating cell-free DNA infers breast cancer dormancy. (2012) (0)
- Faculty Opinions recommendation of Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. (2011) (0)
- ThePutative trans-Activator intheMA9'9Region ofRousSarcoma Virus IsNotRequired forCellTransformation (1988) (0)
- Faculty Opinions recommendation of Programmed genome rearrangements in Oxytricha produce transcriptionally active extrachromosomal circular DNA. (2019) (0)
- Abstract 1909: Identification and characterization of microRNA-134 as a novel receptor tyrosine kinase-regulated tumor suppressive hub in glioblastoma (2014) (0)
- Faculty Opinions recommendation of Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53. (2005) (0)
- Facial Nerve Neuroma : A Case Report. (2005) (0)
- Abstract 1771: Extrachromosomal microDNAs in normal vertebrate tissues. (2013) (0)
- Faculty Opinions recommendation of Cell type-specific responses of human cells to inhibition of replication licensing. (2004) (0)
- Total bladder replacement by detubularised sigmoid colon segment. (1994) (0)
- A mechanism for sequential replication‐coupled destruction of CRL4‐Cdt2 substrates (616.1) (2014) (0)
- Faculty Opinions recommendation of Tipin/Tim1/And1 protein complex promotes Pol alpha chromatin binding and sister chromatid cohesion. (2010) (0)
- Faculty Opinions recommendation of RNA-guided human genome engineering via Cas9. (2013) (0)
- Faculty Opinions recommendation of Genomic Copy-Number Loss Is Rescued by Self-Limiting Production of DNA Circles. (2019) (0)
- Studies on the Activity of the Long Terminal Repeat of Rous Sarcoma Virus in Animal Cells and in Yeast (1989) (0)
- Faculty Opinions recommendation of Long noncoding RNAs with snoRNA ends. (2013) (0)
- A comparative study of single layer InAs SK, SML, and coupled SK-on-SML QDs heterostructure by incorporating InGaAsSb (Type-II) as capping layer (2022) (0)
- Controlling foamability of polypropylene/γ-irradiated ethylene acrylic elastomer blends by extent of crosslinking and domain microstructure of elastomer (2021) (0)
- CSIG-07. GAIN-OF-FUNCTION MUTANT P53 REGULATES LONG-NONCODING RNAS IN GLIOBLASTOMA (2022) (0)
- Mechanism and Regulation of DNA Replication Lessons from Sv-40 (1991) (0)
- The genomics of DNA replication of human chromosomes (2009) (0)
- Analyzing DNA Replication Timing in the Human Genome (2009) (0)
- Lipid Clustering within Mycobacterial Cell Envelope Layers Governs Spatially Resolved Solvation Dynamics (2021) (0)
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