Arthur Riggs

Q: What Schools Are Affiliated With Arthur Riggs

Arthur Riggs is affiliated with the following schools: National Chung Hsing University, Tohoku University, University of Leeds, La Trobe University, California Institute of Technology, University of California, Riverside, Columbia University

Arthur Riggs 's AcademicInfluence.com Rankings

Arthur Riggs

Biology

#960

World Rank

#1670

Historical Rank

#511

USA Rank

Molecular Biology

#251

World Rank

#255

Historical Rank

#105

USA Rank

Genetics

#234

World Rank

#281

Historical Rank

#122

USA Rank

biology Degrees

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Biology

Arthur Riggs 's Degrees

PhD Biochemistry California Institute of Technology

Why Is Arthur Riggs Influential?

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According to Wikipedia, Arthur Dale Riggs was an American geneticist who worked with Genentech to express the first artificial gene in bacteria. His work was critical to the modern biotechnology industry because it was the first use of molecular techniques in commercial production of drugs and enabled the large-scale manufacturing of protein drugs, including insulin. He was also a major factor in the origin of epigenetics.

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Arthur Riggs 's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genomic sequencing. (1993) (2898)
DNA methylation and gene function. (1980) (1859)
X inactivation, differentiation, and DNA methylation. (1975) (1203)
Epigenetic mechanisms of gene regulation (1996) (926)
On the mechanism of DNA replication in mammalian chromosomes. (1968) (867)
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. (1977) (759)
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells (2017) (755)
Expression in Escherichia coli of chemically synthesized genes for human insulin. (1979) (741)
The lac repressor-operator interaction. 3. Kinetic studies. (1970) (639)
Lac repressor-operator interaction. I. Equilibrium studies. (1970) (603)
The lac represser-operator interaction (1970) (543)
Clonal analysis using recombinant DNA probes from the X-chromosome. (1987) (457)
Tiggers and DNA transposon fossils in the human genome. (1996) (409)
5-methylcytosine, gene regulation, and cancer. (1983) (407)
Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequences. (1995) (377)
DNA Methylation and Demethylation in Mammals* (2011) (368)
Genomic sequencing and methylation analysis by ligation mediated PCR. (1989) (355)
X-chromosome inactivation and cell memory. (1992) (338)
A human B cell methylome at 100−base pair resolution (2009) (328)
The Histone Methyltransferase SETDB1 and the DNA Methyltransferase DNMT3A Interact Directly and Localize to Promoters Silenced in Cancer Cells* (2006) (318)
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer (2008) (299)
The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes (1975) (298)
The antisense strand of small interfering RNAs directs histone methylation and transcriptional gene silencing in human cells. (2005) (296)
Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay (2007) (284)
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC (2007) (281)
Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. (1990) (271)
Lac repressor binding to non-operator DNA: detailed studies and a comparison of eequilibrium and rate competition methods. (1972) (246)
lac repressor--operator interaction. II. Effect of galactosides and other ligands. (1970) (238)
MIRs are classic, tRNA-derived SINEs that amplified before the mammalian radiation (1995) (233)
DNA methylation, biochemistry, and biological significance (1984) (233)
In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1. (1990) (232)
Measurement by quantitative PCR of changes in HPRT, PGK-1, PGK-2, APRT, MTase, and Zfy gene transcripts during mouse spermatogenesis. (1990) (226)
DNA binding of the lac repressor. (1968) (221)
Methylation of polycomb target genes in intestinal cancer is mediated by inflammation. (2008) (213)
Physical and functional interactions between the human DNMT3L protein and members of the de novo methyltransferase family (2005) (213)
Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern. (1997) (210)
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation (2012) (209)
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations (2008) (207)
Evaluating the Role of Epigenetic Histone Modifications in the Metabolic Memory of Type 1 Diabetes (2014) (196)
Chromatin differences between active and inactive X chromosomes revealed by genomic footprinting of permeabilized cells using DNase I and ligation-mediated PCR. (1991) (180)
Epigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort (2016) (173)
A quantitative HpaII-PCR assay to measure methylation of DNA from a small number of cells. (1990) (172)
Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli. (1984) (167)
Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation (1990) (166)
Interaction of effecting ligands with lac repressor and repressor-operator complex. (1975) (162)
In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction. (1991) (154)
Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function. (1982) (154)
Binding of transcription factors creates hot spots for UV photoproducts in vivo (1992) (152)
High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes (2003) (150)
Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase. (1984) (148)
Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5' end of the gene for phosphoglycerate kinase (1986) (144)
Synthetic lacoperator DNA is functional in vivo (1976) (143)
On the assay, isolation and characterization of the lac repressor. (1968) (143)
DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene. (2005) (140)
Molecular Mechanisms of Chromosome Pairing, Folding and Function (1971) (135)
The tumorigenicity of 5-azacytidine in the male Fischer rat. (1984) (134)
Transcription factor complex formation and chromatin fine structure alterations at the murine c-fms (CSF-1 receptor) locus during maturation of myeloid precursor cells. (2002) (133)
Lac operator analogues: bromodeoxyuridine substitution in the lac operator affects the rate of dissociation of the lac repressor. (1972) (132)
Autoradiography of chromosomal DNA fibers from Chinese hamster cells. (1966) (127)
Epigenetic Silencing May Aid Evolution by Gene Duplication (2003) (122)
MicroRNA-26a targets ten eleven translocation enzymes and is regulated during pancreatic cell differentiation (2013) (122)
Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen. (1988) (121)
Methylation of mouse liver DNA studied by means of the restriction enzymes msp I and hpa II. (1979) (118)
DNA methylation and late replication probably aid cell memory, and type I DNA reeling could aid chromosome folding and enhancer function. (1990) (109)
Genome-wide analysis of histone lysine methylation variations caused by diabetic conditions in human monocytes. (2010) (109)
CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs (2009) (107)
Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance (2013) (106)
Methylation and epigenetic fidelity (2003) (105)
DNA methylation biomarkers for lung cancer (2011) (105)
Methylation dynamics, epigenetic fidelity and X chromosome structure. (1998) (104)
Chromatin fine structure profiles for a developmentally regulated gene: reorganization of the lysozyme locus before trans-activator binding and gene expression. (2000) (103)
Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel (2013) (102)
Cloning of the genes for T84.66, an antibody that has a high specificity and affinity for carcinoembryonic antigen, and expression of chimeric human/mouse T84.66 genes in myeloma and Chinese hamster ovary cells. (1990) (102)
The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts (1998) (100)
Nucleotide Excision Repair Eliminates Unique DNA-Protein Cross-links from Mammalian Cells* (2007) (98)
Overview of Epigenetic Mechanisms (1996) (97)
Purification and DNA-binding properties of the catabolite gene activator protein. (1971) (97)
COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis (2013) (95)
HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence (2005) (93)
A sensitive, quantitative assay for measurement of allele-specific transcripts differing by a single nucleotide. (1992) (93)
Preparation of spermatogonia, spermatocytes, and round spermatids for analysis of gene expression using fluorescence-activated cell sorting. (1995) (91)
Dynamic methylation adjustment and counting as part of imprinting mechanisms. (1996) (87)
Maintenance and regulation of DNA methylation patterns in mammals. (2005) (83)
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model (2016) (82)
Molecular cloning of a gene belonging to the carcinoembryonic antigen gene family and discussion of a domain model. (1987) (80)
Parental imprinting studied by allele-specific primer extension after PCR: paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation. (1992) (79)
GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease. (2018) (79)
Equilibrium binding of inducer to lac repressor.operator DNA complex. (1980) (79)
Methylation of DNA in mouse early embryos, teratocarcinoma cells and adult tissues of mouse and rabbit. (1979) (78)
Photochemical attachment of lac repressor to bromodeoxyuridine-substituted lac operator by ultraviolet radiation. (1974) (76)
X chromosome inactivation and DNA methylation. (1993) (75)
Dynamic reorganization of chromatin structure and selective DNA demethylation prior to stable enhancer complex formation during differentiation of primary hematopoietic cells in vitro. (2004) (74)
Sex chromosome evolution: platypus gene mapping suggests that part of the human X chromosome was originally autosomal. (1991) (71)
Genome-wide Analysis of Histone Lysine Methylation Variations Caused by Diabetic Conditions in Human Monocytes* (2007) (70)
Chemical synthesis of restriction enzyme recognition sites useful for cloning. (1977) (70)
Efficient correction of a mutation by use of chemically synthesized DNA. (1978) (70)
Lac repressor purification without inactivation of DNA binding activity. (1977) (68)
Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis (2016) (68)
Histones bind more tightly to bromodeoxyuridine-substituted DNA than to normal DNA. (1976) (67)
The X chromosome of monotremes shares a highly conserved region with the eutherian and marsupial X chromosomes despite the absence of X chromosome inactivation. (1990) (66)
Identification of Oct4-activating compounds that enhance reprogramming efficiency (2012) (64)
Lac Repressor Binding to DNA not containing the Lac Operator and to Synthetic Poly dAT (1970) (64)
Establishment and characterization of a cell line from the american opossum (Didelphys virginiana) (1978) (63)
Isolation of a cDNA clone for human X-linked 3-phosphoglycerate kinase by use of a mixture of synthetic oligodeoxyribonucleotides as a detection probe. (1983) (61)
5-Methylcytosine content of rat hepatoma DNA substituted with bromodeoxyuridine. (1977) (59)
CpG island clusters and pro-epigenetic selection for CpGs in protein-coding exons of HOX and other transcription factors (2010) (59)
Cloning and physical mapping of a gene fragment coding for a 64-kilodalton major late antigen of human cytomegalovirus. (1984) (58)
Epigenetic stability, adaptability, and reversibility in human embryonic stem cells (2012) (58)
Ribonuclease H (hybrid) in Escherichia coli. Identification and characterization. (1973) (58)
Chromatin structure analysis by ligation-mediated and terminal transferase-mediated polymerase chain reaction. (1999) (56)
Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes (2016) (56)
Developmentally Regulated Recruitment of Transcription Factors and Chromatin Modification Activities to Chicken Lysozyme cis-Regulatory Elements In Vivo (2003) (56)
Tiggers and other DNA transposon fossils in the human genome ( interspersed repeats / pogo / mariner / Tcl / centromere protein CENP-B ) (2005) (56)
Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L. (2006) (56)
Determinator-inhibitor pairs as a mechanism for threshold setting in development: a possible function for pseudogenes. (1986) (54)
Lac repressor-operator interaction. V. Characterization of super- and pseudo-wild-type repressors. (1972) (54)
Evolutionary conservation of the substrate‐binding cleft of phosphoglycerate kinases (1986) (52)
Ligation-mediated PCR for quantitative in vivo footprinting (2000) (52)
Carcinogenicity and haemoglobin synthesis induction by cytidine analogues. (1988) (50)
Terminal transferase-dependent PCR: a versatile and sensitive method for in vivo footprinting and detection of DNA adducts. (1998) (50)
X chromosome inactivation, differentiation, and DNA methylation revisited, with a tribute to Susumu Ohno (2003) (47)
Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes (2016) (46)
Differences in methylation on the active and inactive human X chromosomes (1985) (45)
Purification of human DNA (cytosine‐5‐)‐methyltransferase (1985) (45)
Active human-yeast chimeric phosphoglycerate kinases engineered by domain interchange (1986) (45)
Histone Methylation Patterns Are Cell-Type Specific in Human Monocytes and Lymphocytes and Well Maintained at Core Genes1 (2008) (45)
Chemical DNA synthesis and recombinant DNA studies. (1980) (43)
Epigenetic Changes and Repositioning Determine the Evolutionary Fate of Duplicated Genes (2005) (42)
Ligation-mediated PCR improves the sensitivity of methylation analysis by restriction enzymes and detection of specific DNA strand breaks. (1990) (42)
Real-time PCR assay for quantitative mismatch detection. (2003) (41)
Sensitive detection of 5-methylcytosine and quantitation of the 5-methylcytosine/cytosine ratio in DNA by gas chromatography--mass spectrometry using multiple specific ion monitoring. (1979) (41)
The nucleotide sequence of a cDNA clone containing the entire coding region for mouse X-chromosome-linked phosphoglycerate kinase. (1986) (40)
Marsupials and Mechanisms of X-Chromosome Inactivation (1989) (40)
Mapping Human Pluripotent-to-Cardiomyocyte Differentiation: Methylomes, Transcriptomes, and Exon DNA Methylation “Memories” (2016) (38)
Lac repressor binding to operator analogues: comparison of poly(d(A-T)), poly(d(A-BrU)), and poly(d(A-U)). (1971) (37)
The Histone Methyltransferase KMT2B Is Required for RNA Polymerase II Association and Protection from DNA Methylation at the MagohB CpG Island Promoter (2013) (37)
Analysis of methylation and chromatin structure. (1993) (37)
Expression in Escherichia coli of a chemically synthesized gene for a "mini-C" analog of human proinsulin. (1981) (37)
Epigenetic Silencing and Activation of a Maize r Gene (1996) (36)
Quantitative analysis of messenger RNA levels: reverse transcription-polymerase chain reaction single nucleotide primer extension assay. (1993) (36)
A comparison of lac repressor binding to operator and to nonoperator DNA. (1975) (36)
Detection of antisense and ribozyme accessible sites on native mRNAs: application to NCOA3 mRNA. (2001) (35)
Site-directed mutagenesis of glutamate-190 in the hinge region of yeast 3-phosphoglycerate kinase: implications for the mechanism of domain movement. (1987) (34)
The binding of lac repressor and the catabolite gene activator protein to halogen-substituted analogues of poly[d(A-T)]. (1976) (34)
Lac repressor binding to synthetic DNAs of defined nucleotide sequence. (1972) (32)
A potentially critical Hpa II site of the X chromosome-linked PGK1 gene is unmethylated prior to the onset of meiosis of human oogenic cells. (1992) (32)
The chicken lysozyme chromatin domain contains a second, widely expressed gene. (2002) (31)
Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes. (1995) (31)
SR4 Uncouples Mitochondrial Oxidative Phosphorylation, Modulates AMP-dependent Kinase (AMPK)-Mammalian Target of Rapamycin (mTOR) Signaling, and Inhibits Proliferation of HepG2 Hepatocarcinoma Cells* (2015) (30)
Oligonucleotide scanning of native mRNAs in extracts predicts intracellular ribozyme efficiency: ribozyme-mediated reduction of the murine DNA methyltransferase. (2000) (29)
Deletion of a direct repeat element has no effect on Igf2 and H19 imprinting (2001) (29)
Extension product capture improves genomic sequencing and DNase I footprinting by ligation-mediated PCR. (1992) (29)
SAIC: an iterative clustering approach for analysis of single cell RNA-seq data (2017) (28)
Repositioning-dependent fate of duplicate genes. (2005) (28)
Bacterial Production of Human Insulin (1981) (28)
Rlip depletion prevents spontaneous neoplasia in TP53 null mice (2018) (27)
DNA affinity capture and protein profiling by SELDI-TOF mass spectrometry: effect of DNA methylation. (2002) (26)
Killer cell Ig-like receptor (KIR) 3DL1 down-regulation enhances inhibition of type 1 diabetes by autoantigen-specific regulatory T cells (2011) (26)
Genomic footprinting by ligation mediated polymerase chain reaction. (1993) (26)
The lac repressor-operator interaction. IV. Assay and purification of operator DNA. (1970) (26)
Methylation analysis by genomic sequencing of 5′ region of mousePgk-1 gene and a cautionary note concerning the method (1993) (26)
Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. (2016) (25)
Methylation of the PGK promoter region and an enhancer way-station model for X-chromosome inactivation. (1985) (24)
Mouse endogenous X-linked genes do not show lineage-specific delayed inactivation during development. (1995) (24)
Terminal Transferase-Dependent PCR (TDPCR) for In Vivo UV Photofootprinting of Vertebrate Cells (2001) (24)
DNA methylation mediates development of HbA1c-associated complications in type 1 diabetes (2020) (24)
In Vivo Ultraviolet and Dimethyl Sulfate Footprinting of the 5′ Region of the Expressed and Silent XistAlleles* (1997) (24)
SMC1A is associated with radioresistance in prostate cancer and acts by regulating epithelial‐mesenchymal transition and cancer stem‐like properties (2018) (23)
Immunoglobulin transcripts and molecular history of a hybridoma that produces antibody to carcinoembryonic antigen. (1985) (23)
In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice. (2014) (22)
Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome. (2005) (21)
Mapping psoralen cross-links at the nucleotide level in mammalian cells: suppression of cross-linking at transcription factor- or nucleosome-binding sites. (2001) (21)
Making, Cloning, and the Expression of Human Insulin Genes in Bacteria: The Path to Humulin (2020) (19)
Epigenetics and Evolution: Transposons and the Stochastic Epigenetic Modification Model (2015) (18)
Enhanced evolution by stochastically variable modification of epigenetic marks in the early embryo (2014) (18)
In vivo, high-resolution analysis of yeast and mammalian RNA-protein interactions, RNA structure, RNA splicing and ribozyme cleavage by use of terminal transferase-dependent PCR. (2000) (18)
PCR-aided DNaseI footprinting of single copy gene sequences in permeabilized cells. (1990) (18)
Synthetic DNA and medicine. (1979) (17)
Bioenergetic modulation with the mitochondria uncouplers SR4 and niclosamide prevents proliferation and growth of treatment-naïve and vemurafenib-resistant melanomas (2018) (17)
DNA methylation and cell memory (1989) (16)
Genomic sequencing by ligation-mediated PCR (1996) (16)
Ligation-mediated PCR for chromatin-structure analysis of interphase and metaphase chromatin. (1997) (16)
X-Chromosome Inactivation and Epigenetic Mechanisms (1996) (16)
Differential replication timing of X-linked genes measured by a novel method using single-nucleotide primer extension. (1998) (16)
Inhibition of S-phase kinase-associated protein 2 (Skp2) reprograms and converts diabetogenic T cells to Foxp3+ regulatory T cells (2012) (16)
2'-Hydroxyflavanone: A promising molecule for kidney cancer prevention. (2015) (15)
A Functional Chromatin Domain Does Not Resist X Chromosome Inactivation: Silencing of cLys Correlates with Methylation of a Dual Promoter-Replication Origin (2002) (15)
X Inactivation, DNA Methylation, and Differentiation Revisited (1984) (15)
Tissue-resident PSGL1loCD4+ T cells promote B cell differentiation and chronic graft-versus-host-disease-associated autoimmunity. (2020) (14)
The Role of DNA Methylation in Plant Development (1996) (14)
Introduction and General Overview (1984) (14)
Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses (2021) (14)
Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro. (2015) (13)
Analysis of high-resolution 3D intrachromosomal interactions aided by Bayesian network modeling (2017) (13)
A complex duplication created by gene targeting at the imprinted H19 locus results in two classes of methylation and correlated Igf2 expression phenotypes. (2001) (12)
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice (2015) (12)
DNA methylation mediates HbA1c-associated complications development in Type 1 diabetes (2020) (12)
Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis (2021) (12)
Examination of the DNA substrate selectivity of DNA cytosine methyltransferases using mass tagging. (2000) (11)
Frequent monoallelic or skewed expression for developmental genes in CNS-derived cells and evidence for balancing selection (2018) (11)
Epigenetic modifications and gene silencing in plants. (1996) (11)
Multipotent progenitor cells isolated from adult human pancreatic tissue. (2005) (10)
Rapid, solid-phase based automated analysis of chromatin structure and transcription factor occupancy in living eukaryotic cells (2005) (10)
Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice (2020) (10)
IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice (2021) (9)
DNA binding factors for the CpG-rich island containing the promoter of the human X-linkedPGK gene (1988) (9)
Mammalian X-chromosome inactivation. (1983) (8)
Ligation-mediated PCR: robotic liquid handling for DNA damage and repair. (2002) (8)
A Simple and Cost-Effective Approach for In Vitro Production of Sliced siRNAs as Potent Triggers for RNAi (2017) (8)
An epigenetic perspective on the failing heart and pluripotent-derived-cardiomyocytes for cell replacement therapy (2015) (7)
Colony-forming progenitor cells in the postnatal mouse liver and pancreas give rise to morphologically distinct insulin-expressing colonies in 3D cultures. (2014) (7)
In Vitro Colony Assays for Characterizing Tri-potent Progenitor Cells Isolated from the Adult Murine Pancreas. (2016) (7)
Large-scale purification of two forms of active lac operator from plasmids. (1980) (6)
FROM CHINESE HAMSTER CELLS (2016) (6)
Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity. (2021) (6)
Use of terminal transferase-dependent antisense RNA amplification to determine the transcription start site of the Snrpn gene in individual neurons. (2000) (6)
Gene mapping studies confirm the homology between the platypus X and echidna X1 chromosomes and identify a conserved ancestral monotreme X chromosome (1992) (6)
Mechanism of DNA methlyation in vertebrates and its biological significance. (1996) (5)
Directed mutagenesis as a technique to study protein function: application to beta-lactamase. (1984) (5)
Differences in silencing of mismatched targets by sliced versus diced siRNAs (2018) (5)
MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice (2018) (5)
Inhibition of p38 mitogen-activated protein kinase protects human islets from cryoinjury and improves the yield, viability, and quality of frozen-thawed islets. (2005) (4)
COHCAP: an integrative genomic pipeline for single-nucleotide resolution DNA methylation analysis (2019) (4)
Elimination of human folypolyglutamate synthetase alters programming and plasticity of somatic cells (2019) (4)
In vivo detection of ribozyme cleavage products and RNA structure by use of terminal transferase-dependent PCR. (2004) (3)
PAP-LMPCR for improved, allele-specific footprinting and automated chromatin fine structure analysis (2008) (3)
Synthesis, cloning, and expression of hormone genes in Escherichia coli. (1980) (3)
Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice. (2020) (3)
A method for establishing cell lines fromDrosophila melanogaster embryos (2007) (3)
PD-L1/CD80 and PD-L1/PD-1 Signaling Reciprocally Regulate Alloreactive CD8+ T Cell Glycolysis, Proliferation, Apoptosis and Gvhd-Inducing Capacity (2015) (3)
Analysis of RNA structure and RNA-protein interactions in mammalian cells by use of terminal transferase-dependent PCR. (2008) (2)
Proteins to Order Use of Synthetic DNA to Generate Site-Specific Mutations (1982) (2)
Abstract 220: SR4 uncouples mitochondrial oxidative-phosphorylation, modulates AMPK-mTOR signaling, and inhibits proliferation of HepG2 hepatocarcinoma cells (2016) (2)
5-Azacytidine. Promoting activity for rat hepatocellular carcinoma. (1984) (2)
Abstract 3180: Blockade of PD-L1 interaction with CD80in transaugments anti-tumor immunity by increasing NOS2 in tumor-associated macrophages (2021) (1)
WRNIP1 is a key regulator of antigen-specific Treg cells. (IRC4P.480) (2014) (1)
Mapping Oxidative DNA Damage at Nucleotide Resolution in Mammalian Cells (2002) (1)
Metaphase synchronization and chromosome preparation from the OK opossum cell line having a potentially isolatable X chromosome (1984) (1)
Polymerase Chain Reaction-Aided Genomic Footprinting: Principles and Applications (1997) (1)
G-Quadruplex Helicase DHX36/G4R1 Engages Nuclear Lamina Proteins in Quiescent Breast Cancer Cells (2020) (1)
THE INTERACTION OF CHEMICALLY SYNTHESIZED 21 BASE PAIR LAC OPERATOR WITH THE LAC REPRESSOR (1976) (1)
Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene (2022) (1)
Abstract 2160: Targeting SMC1 in combination therapy for triple negative breast cancer (2016) (1)
DNA methylation mediates development of HbA1c-associated complications in type 1 diabetes (2020) (1)
Patents and literature (1986) (1)
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. 1977. (1992) (1)
Essentials of Mouse Development (1996) (1)
A method of producing an immunoglobulin comprising heavy and light chain, with specificity for a particular identified antigen, replicable expression vectors comprising DNA sequences coding for, respectively, the heavy and light chains, and recombinant host cells transformed with the vectors (1992) (0)
Molecular cloning of macro molecular binding domains of human fibronectin (1982) (0)
Part I. Studies on Mycoplasm gallisepticum. Part II. Autoradiography of Chromosomal DNA Fibers from Chinese Hamster Cells (1966) (0)
Methode d'identification de sites de liaison accessibles dans l'arn (2000) (0)
Preface/Front Matter (1996) (0)
Tribute to promethean thinker - in memory of Susumu Ohno (2008) (0)
IFN-γ-deficient transplant induces acute gut GVHD via dysregulation of RagIIIγ and intestinal microbiota (2017) (0)
Method mocrobienne permitting expression of polypeptides and appropriate means (1979) (0)
Recombinant immunoglobulin preparations, methods for their preparation, DNA sequences, expression vectors and recombinant cells operatively here for. (1984) (0)
Tc17 cells mediate gut GVHD via IL-22 and dysbiosis (2018) (0)
X-Chromosome Clonal Analysis Using Recombinant DNA Probes from the Updated (2006) (0)
MHC-mismatched mixed chimerism augments thymic regulatory T cell production and prevents relapse of EAE (THER7P.960) (2015) (0)
Riggs AD Co-Editor-in-Chief. (2007) (0)
SAIC: an iterative clustering approach for analysis of single cell RNA-seq data (2017) (0)
Donor PD-L1 is required for organ transplant tolerance in MHC-mismatched mixed chimeras while PD-L1 and MHCII are not required for inducing chimerism. (2023) (0)
Tc17 cells cause gut graft-versus-host disease through induction of dysbiosis and depletion of CX3CR1hi phagocytes (2020) (0)
From Somatostatin to Human Insulin (2018) (0)
Lac Repressor Binding to Synthetic DNA (2016) (0)
474. Process Development for Scalable Manufacturing of hESC-Derived Cardiomyocytes (2016) (0)
Non-glycosylated chimeric immunoglobulin species (1984) (0)
P34 12 TP – MAPPING OF UV-INDUCED ADDUCTS AT THE DNA SEQUENCE LEVEL IN A HUMAN SINGLE COPY GENE (1991) (0)
Stat3-/- Alloreactive Donor T Cells Reduce FAO but Increase Leakage of ROS in Response to PD-1 Signaling Triggered By Host-Tissue PD-L1, Leading to Prevention of Gvhd While Preserving GVL Effect (2019) (0)
Evolution Sex chromosome evolution : Platypus gene mapping suggests that part of the human X chromosome was originally autosomal ( sex chromosomies / a lgenome evolution / X chromosome inactivation ) (0)
Modern Biotechnology" The Citrus College STEM Speaker Series Presents... (2009) (0)
Blockade of CD80 interaction with PD-L1 between T and tumor cells augments effector T expansion and tumor immunity in a PD-1-dependent manner (2020) (0)
Towards a Rational Balanced Pancreatic and Islet Allocation Schema (2021) (0)
Methylated-CpG island recovery assay-assisted microarrays for cancer diagnosis. (2007) (0)
Methylation of the 3 phosphoglycerate kinase promoter region and an enhancer way station model for x chromosome inactivation (1985) (0)
Synthetic dna and process for their manufacture (1978) (0)
Method and means for microbial polypeptide forcing out (1978) (0)
260-OR: Transdifferentiation of a-Cells and Redifferentiation of InsulinLo ß-Cells Dominate ß-Cell Regeneration in Late-Stage Diabetic NOD Mice Cured with Induction of Mixed Chimerism and Administration of Gastrin and Epidermal Growth Factor (2020) (0)
Purification andDNA-Binding Properties oftheCatabolite GeneActivator Protein (1971) (0)
Patents And literature (1985) (0)
Photochemical Attachment of lac Repress Substituted lac Operator by Ultraviolet R (2016) (0)
MHC-mismatched but not matched mixed chimerism can tolerize peripheral non-cross-reactive autoreactive T cells in type 1 diabetic NOD mice (2016) (0)
INCREASED C-TERMINAL LYSINE IN A RECOMBINANT MONOCLONAL ANTIBODY PRODUCTION USING CHINESE HAMSTER OVARY CELLS WITH CHEMICALLY DEFINED MEDIA (2012) (0)
Chimeric anti-cae-antibodies. (1990) (0)
Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity (2023) (0)
Identification of a distinct ductal subpopulation with self-renewal and differentiation potential from the adult murine pancreas (2022) (0)
Viral and Host Small RNA Response to SARS-CoV-2 Infection (2022) (0)
A recombinant plasmid, process for the preparation of the plasmid, bacteria containing the plasmid, and method for f (1978) (0)
An improved method to map DNA lesions at nucleotide resolution : ligation-mediated PCR with ribonucleotide tailing by terminal deoxynucleotidyl transferase. (1997) (0)
INCREASED C-TERMINAL LYSINE IN A RECOMBINANT MONOCLONAL ANTIBODY PRODUCTION USING CHINESE HAMSTER OVARY CELLS WITH CHEMICALLY DEFINED MEDIA (2012) (0)
Reassessing the Abundance of miRNAs in the Human Pancreas and Rodent Cell Lines and Its Implication (2022) (0)
Studies of protein function by various mutagenic strategies: beta-lactamase. (1984) (0)
Methylcellulose colony assay and single-cell micro-manipulation reveal progenitor-like cells in adult human pancreatic ducts (2023) (0)
Abstract 5244: Partial knockdown of RLIP76 prevents cancer susceptibility of p53 null mice (2017) (0)
A process for preparing an immunoglobulin comprising heavy and light chain, with specificity for a particular identified antigen, DNA sequences encoding same, replicable expression vectors for the DNA sequences and recombinant host cells transformed with the vectors (1992) (0)
A potentially critical Hpa II site of the X chromosome-linked PGKI gene is unmethylated prior to the onset of meiosis of human oogenic cells (development/X chromosome inactivation/DNA methylation/polymerase chain reaction/phosphoglycerate kinase) (2016) (0)
PAP-LMPCR: an improved, sequence-selective method for the in vivo analysis of transcription factor occupancy and chromatin fine structure. (2011) (0)
Lacrepressor purification without inactivation ofDNAbinding activity (1977) (0)
Molecular cloning and expression of epstein barr virus genes in escherichia coli (1987) (0)
PD-L1/CD80 interaction differentially regulates CD8+ T cell metabolism, survival and GVHD capacity in the presence or absence of PD-1 (2017) (0)
Molecular cloning of a full length nca normal cross reacting antigen complementary dna and comparison to carcinoembryonic antigen (1987) (0)
Promoter CpG Island MagohB Methylation at the Association and Protection from DNA Required for RNA Polymerase II The Histone Methyltransferase KMT2B Is (2014) (0)
Anticorps chimerique anti-antigene carcinoembryonique (1990) (0)

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