Robert F. Furchgott

About

From Wikipedia

Robert Francis Furchgott was a Nobel Prize-winning American biochemist who contributed to the discovery of nitric oxide as a transient cellular signal in mammalian systems.Early life and education Furchgott was born in Charleston, South Carolina, to Arthur Furchgott , a department store owner, and Pena Furchgott. He graduated with a degree in chemistry from the University of North Carolina at Chapel Hill , and went on to earn a Ph.D in biochemistry at Northwestern University , immediately joining a medical faculty thereafter.

Published Works

• The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
• Role of endothelium in responses of vascular smooth muscle.
• Endothelium‐derived relaxing and contracting factors
• The Role of Endothelium in the Responses of Vascular Smooth Muscle to Drugs
• COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS
• THE PHARMACOLOGICAL DIFFERENTIATION OF ADRENERGIC RECEPTORS
• Role of endothelial cells in relaxation of isolated arteries by bradykinin.
• Endothelium-Derived Relaxing Factor: Discovery, Early Studies, and Identifcation as Nitric Oxide (Nobel Lecture)
• Endothelial Cells as Mediators of Vasodilation of Arteries
• The requirement for endothelial cells in the relaxation of arteries by acetylcholine and some other vasodilators
Endothelium-Derived Relaxing Factor: Discovery, Early Studies, and Identification as Nitric Oxide
The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory
The Photoactivated Relaxation of Smooth Muscle of Rabbit Aorta
The 1989 Ulf von Euler Lecture Studies on endothelium-dependent vasodilation and the endothelium-derived relaxing factor
Receptor Mechanisms
The Discovery of Endothelium-Derived Relaxing Factor and Its Importance in the Identification of Nitric Oxide
Biphasic Vasoconstriction of the Rabbit Ear Artery
ON THE OCCURRENCE, SITES AND MODES OF ORIGIN AND DESTRUCTION, OF PRINCIPLES AFFECTING THE COMPENSATORY VASCULAR MECHANISMS IN EXPERIMENTAL SHOCK
ELECTROPHORETIC STUDIES ON HUMAN RED BLOOD CELLS
Hepatorenal Factors in Circulatory Homeostasis
High Energy Phosphates and the Force of Contraction of Cardiac Muscle
Relaxation of Mammalian Smooth Muscles by Visible and Ultraviolet Radiation
Release of Autonomic Mediators in Cardiac Tissue by Suprathreshold Stimulation
THE DETERMINATION OF INORGANIC PHOSPHATE AND CREATINE PHOSPHATE IN TISSUE EXTRACTS
HEPATO-RENAL FACTORS IN CIRCULATORY HOMEOSTASIS: III. THE INFLUENCE OF HUMORAL FACTORS OF HEPATO-RENAL ORIGIN ON THE VASCULAR REACTIONS TO HEMORRHAGE
The 1996 Albert Lasker Medical Research Awards. The discovery of endothelium-derived relaxing factor and its importance in the identification of nitric oxide
Action potentials of guinea pig atria under conditions which alter contraction
A Research Trail Over Half a Century
Der relaxierende Faktor aus Endothelzellen: Entdeckung, frühe Untersuchungen und Identifizierung als Stickstoffmonoxid (Nobel-Vortrag)
Disk-Sphere Transformation in Mammalian Red Cells
Endothelium-Dependent and -Independent Vasodilation Involving Cyclic GMP: Relaxation Induced by Nitric Oxide, Carbon Monoxide and Light
Vasodilation Induced by Acetylcholine and by Glyceryl Trinitrate in Rat Aortic and Mesenteric Vasculature
Introduction to EDRF Research
Interactions of Endothelial Cells and Smooth Muscle Cells of Arteries
Catecholamines
ANTAGONISM OF PROPRANOLOL TO ISOPROTERENOL IN GUINEA-PIG TRACHEA: SOME CAUTIONARY FINDINGS
INFRA-RED ABSORPTION SPECTRA OF STEROIDS
PHOSPHATE EXCHANGE IN RESTING CARDIAC MUSCLE AS INDICATED BY RADIOACTIVITY STUDIES. IV
OBSERVATIONS ON THE STRUCTURE OF RED CELL GHOSTS
Disk-Sphere Transformation in Mammalian Red Cells
Utilization of Compounds of Krebs Cycle for Contraction Energy by Rabbit Intestinal Smooth Muscle
Postsynaptic Adrenergic Receptor Mechanisms in Vascular Smooth Muscle1
Effect of pH on Contractile Activity of Rabbit Intestinal Smooth Muscle With and Without Added Substrates
THE EFFECT OF SUCCINATE ON RESPIRATION AND CERTAIN METABOLIC PROCESSES OF MAMMALIAN TISSUES AT LOW OXYGEN TENSIONS IN VITRO
Sources of Energy for Intestinal Smooth Muscle Contraction*
INFRA-RED ABSORPTION SPECTRA OF STEROIDS
Introduction to EDRF Research
Evidence for Endothelium-Dependent Vasodilation of Resistance Vessels by Acetylcholine
EVIDENCE FOR BOTH β1 and β2 RECEPTORS IN GUINEA-PIG TRACHEAL SMOOTH MUSCLE AND VARIATION OF THE β1 : β2 RAT10 I N DIFFERENT ANIMALS
EFFECT OF ANOXIA ON CONTRACTILITY AND METABOLISM OF INTESTINAL SMOOTH MUSCLE
Endothelium-Dependent Relaxation in Systemic Arteries
An historical survey and prospects of research on EDRF.
Comparison of endothelium-dependent relaxation by acetylcholine and endothelium-independent relaxation by light in the rabbit aorta
INFRA-RED ABSORPTION SPECTRA OF STEROIDS
THE ELECTROPHORETIC MOBILITY OF RABBIT ERYTHROCYTES AND GHOSTS
Effects of Various Agents on Photorelaxation of Rabbit Aortic Strips1
Comparison of Properties of Nitric Oxide and Endothelium-Derived Relaxing Factor: Some Cautionary Findings
Comparison of nitric oxide, S-nitrosocysteine and EDRF as relaxants of rabbit aorta
SOME COMMENTS ON THE NATURE OF THE RESTITUTION PROCESS OCCURRING BETWEEN BEATS IN CARDIAC MUSCLE
Assay of Catechol Amines in Urine by Means of a Strip of Rabbit Aorta
Receptors for Sympathomimetic Amines
36 Competition between β-haloalkylamines and norepinephrine for sites in cardiac muscle
INFRA-RED ABSORPTION SPECTRA OF STEROIDS
Interactions of endothelial cells and smooth muscle cells of arteries
A Comparison of the Properties of EDRF, Nitric Oxide, and S-Nitrosocysteine
Endothelium-Dependent Vasodilation and the Nature of the Endothelium-Derived Relaxing Factor
NO and diabetic complications
Effects of hydrogen peroxide on rabbit aortic rings*1
Effect of different oxygen tensions on the nitric oxide-induced relaxation of rabbit aortic rings
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Washington University in St. Louis

University in St. Louis, Missouri, United States

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University of Miami

Private university in Coral Gables, Florida, United States

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University of North Carolina at Chapel Hill

Public research university in Chapel Hill, North Carolina, United States

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Cornell University

Private university in Ithaca

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University of South Carolina

University in Columbia, South Carolina

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Northwestern University

Private research university with campuses in Evanston and Chicago, Illinois, United States

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