Mildred Cohn
#26,308
Most Influential Person
American biochemist
Why Is Mildred Cohn Influential?
(Suggest an Edit or Addition)According to Wikipedia, Mildred Cohn was an American biochemist who furthered understanding of biochemical processes through her study of chemical reactions within animal cells. She was a pioneer in the use of nuclear magnetic resonance for studying enzyme reactions, particularly reactions of adenosine triphosphate .
Mildred Cohn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Papers
- Nuclear magnetic resonance spectra of adenosine di- and triphosphate. II. Effect of complexing with divalent metal ions. (1962) (333)
- Oxygen Exchange Reactions of Organic Compounds and Water (1938) (262)
- Kinetic and magnetic resonance studies of the pyruvate kinase reaction. II. Complexes of enzyme, metal, and substrates. (1966) (193)
- A Study of Manganous Complexes by Paramagnetic Resonance Absorption (1954) (174)
- Isotopic (18O) shift in 31P nuclear magnetic resonance applied to a study of enzyme-catalyzed phosphate--phosphate exchange and phosphate (oxygen)--water exchange reactions. (1978) (152)
- 31P nuclear magnetic resonance spectra of the thiophosphate analogues of adenine nucleotides; effects of pH and Mg2+ binding. (1978) (150)
- MAGNETIC RESONANCE STUDIES OF THE INTERACTION OF THE MANGANOUS ION WITH BOVINE SERUM ALBUMIN. (1963) (144)
- MAGNETIC RESONANCE STUDIES OF METAL ACTIVATION OF ENZYMIC REACTIONS OF NUCLEOTIDES AND OTHER PHOSPHATE SUBSTRATES. (1963) (138)
- KINETIC AND MAGNETIC RESONANCE STUDIES OF THE PYRUVATE KINASE REACTION. I. DIVALENT METAL COMPLEXES OF PYRUVATE KINASE. (1965) (115)
- Magnetic resonance studies of manganese (II) binding sites of pyruvate kinase. Temperature effects and frequency dependence of proton relaxation rates of water. (1970) (114)
- Phosphorus magnetic resonance spectra of adenosine di- and triphosphate. I. Effect of pH. (1960) (110)
- Divalent cation-dependent stereospecificity of adenosine 5'-O-(2-thiotriphosphate) in the hexokinase and pyruvate kinase reactions. The absolute stereochemistry of the diastereoisomers of adenosine 5'-O-(2-thiotriphosphate). (1978) (102)
- Magnetic Resonance Investigations of Ternary Complexes of Enzyme–Metal–Substrate (1962) (97)
- Structural changes induced by substrates and anions at the active site of creatine kinase. Electron paramagnetic resonance and nuclear magnetic relaxation rate studies of the manganous complexes. (1972) (93)
- Functional pools of oxidative and glycolytic fibers in human muscle observed by 31P magnetic resonance spectroscopy during exercise. (1987) (91)
- Proton magnetic relaxation studies of marganous complexes of transfer RNA and related compounds. (1969) (91)
- A study of oxidative phosphorylation with O18-labeled inorganic phosphate. (1953) (90)
- Electron paramagnetic resonance spectra of manganese (II)-protein complexes. Manganese (II)-concanavalin A. (1970) (88)
- Mechanisms of cleavage of glucose-1-phosphate. (1949) (87)
- Diastereomers of the nucleoside phosphorothioates as probes of the structure of the metal nucleotide substrates and of the nucleotide binding site of yeast hexokinase. (1979) (85)
- Kinetic and magnetic resonance studies of pyruvate kinase. 3. The enzyme-metal-phosphoryl bridge complex in the fluorokinase reaction. (1967) (81)
- Enhancement of Tb(III) and Eu(III) fluorescence in complexes with Escherichia coli tRNA. (1974) (80)
- THE ACCUMULATION OF DIVALENT IONS BY ISOLATED MITOCHONDRIA (1963) (72)
- Phosphate-water exchange reaction catalyzed by inorganic pyrophosphatase of yeast. (1958) (71)
- THE TRANSFER OF THE METHYL GROUP FROM METHIONINE TO CHOLINE AND CREATINE (1940) (71)
- NMR studies of a complex of deuterated calmodulin with melittin. (1986) (68)
- Inhibition of rate of tumor growth by creatine and cyclocreatine. (1993) (67)
- Aspects of enzyme mechanisms studies by nuclear spin relazation induced by paramagnetic probes. (2006) (67)
- Analysis of equilibrium data from proton magnetic relaxation rates of water for manganese-nucleotide-kinase ternary complexes. (1970) (66)
- 31P NMR studies of enzyme-bound substrates of rabbit muscle pyruvate kinase. Equilibrium constants, exchange rates, and NMR parameters. (1979) (63)
- 31P NMR study of bound reactants and products of yeast 3-phosphoglycerate kinase at equilibrium and the effect of sulfate ion. (1978) (63)
- Note on the Distinction between Transverse and Longitudinal Electron Relaxation Times Obtained from Nuclear Relaxation Studies (1970) (63)
- ON THE MECHANISM OF THE CONVERSION IN VIVO OF METHIONINE TO CYSTINE (1944) (60)
- The role of the lysyl residue at the active site of creatine kinase. Nuclear Overhauser effect studies. (1974) (58)
- Isotopic oxygen-18 shifts in phosphorus-31 NMR of adenine nucleotides synthesized with oxygen-18 in various positions (1980) (57)
- Magnetic resonance studies of spin-labeled creatine kinase system and interaction of two paramagnetic probes. (1969) (57)
- A study with O18 of adenosine triphosphate formation in oxidative phosphorylation. (1955) (56)
- APPLICATION OF NUCLEAR MAGNETIC RESONANCE IN BIOCHEMISTRY. (1964) (55)
- Nutrition classics from The Journal of Biological Chemistry 140:625-641, 1941. The utilization of the methyl group of methionine in the biological synthesis of choline and creatine. (1941) (54)
- Magnetic resonance studies of enzymesubstrate complexes with paramagnetic probes as illustrated by creatine kinase (1970) (52)
- The Mechanism of the Alkaline Hydrolysis of Ribonucleic Acids (1954) (51)
- Magnetic resonance investigations of the metal complexes formed in the manganese-activated creatine kinase reaction. (1966) (50)
- Energy metabolism of the untrained muscle of elite runners as observed by 31P magnetic resonance spectroscopy: evidence suggesting a genetic endowment for endurance exercise. (1988) (50)
- Nuclear magnetic resonance assignment of the vinyl hydrogens of phosphoenolpyruvate. Stereochemistry of the enolase reaction. (1970) (49)
- Electron paramagnetic resonance studies of manganese (II)-pyruvate kinase-substrate complexes. (1973) (48)
- Specificity of creatine kinase for guanidino substrates. Kinetic and proton nuclear magnetic relaxation rate studies. (1972) (48)
- Cation requirements of isoleucyl-tRNA synthetase from Escherichia coli. (1972) (47)
- Kinetics of polymerization and phosphorolysis reactions of E. coli polynucleotide phosphorylase. Role of oligonucleotides in polymerization. (1970) (46)
- Nucleotide specificity and conformation of the active site of creatine kinase. Magnetic resonance and sulfhydryl reactivity studies. (1966) (46)
- Differentiation of nucleotide binding sites and role of metal ion in the adenylate kinase reaction by 31P NMR. Equilibria, interconversion rates, and NMR parameters of bound substrates. (1978) (45)
- 31P NMR studies of the arginine kinase reaction. Equilibrium constants and exchange rates at stoichiometric enzyme concentration. (1976) (45)
- 31P NMR of enzyme-bound substrates of rabbit muscle creatine kinase. Equilibrium constants, interconversion rates, and NMR parameters of enzyme-bound complexes. (1981) (44)
- Magnetic resonance study of the three-dimensional structure of creatine kinase-substrate complexes. Implications for substrate specificity and catalytic mechanism. (1976) (43)
- The mechanism of the phosphoglucomutase reaction. (1949) (43)
- Phosphoenolpyruvate synthetase of Escherichia coli. Purification, some properties, and the role of divalent metal ions. (1970) (42)
- Magnetic resonance studies of substrate and inhibitor binding to porcine muscle adenylate kinase. (1973) (41)
- Some properties of the phosphorothioate analogs of adenosine triphosphate as substrates of enzymic reactions (1982) (40)
- Proton magnetic resonance spectra or porcine muscle adenylate kinase and substrate complexes. (1975) (40)
- Fluorescent and spin label probes of the environments of the sulfhydryl groups of porcine muscle adenylate kinase. (1975) (40)
- Interaction of manganous ion, substrates, and anions with arginine kinase. Magnetic relaxation rate studies of water protons and kinetic anion effects. (1974) (40)
- Paramagnetic probes in magnetic resonance studies of phosphoryl transfer enzymes (1971) (39)
- Creatine and cyclocreatine effects on ischemic myocardium: 31P nuclear magnetic resonance evaluation of intact heart. (1992) (39)
- On the mechanism of action of muscle and potato phosphorylase. (1948) (37)
- 31P nuclear magnetic resonance of bound substrates of arginine kinase reaction: chemical shifts in binary, ternary, quaternary, and transition state analog complexes. (1977) (37)
- 18O and 17O effects on 31P NMR as probes of enzymatic reactions of phosphate compounds. (1982) (36)
- Mechanisms of enzymic cleavage of some organic phosphates. (1959) (36)
- Metal dependence of the phosphate (oxygen)-water exchange reaction of Escherichia coli alkaline phosphatase. Kinetics followed by 31P(18O) NMR. (1978) (32)
- Proton nuclear magnetic resonance of spin-labeled Escherichia coli tRNAf1MET. (1975) (31)
- The utilization of the methyl groups of choline in the biological synthesis of methionine. (1943) (30)
- 19F nuclear magnetic resonance of 5-fluorouridine-substituted tRNA1Val from Escherichia coli. (1977) (30)
- On the mode of action of 2, 4-dinitrophenol in uncoupling oxidative phosphorylation. (1958) (30)
- Magnetic resonance studies of the manganese guanosine di- and triphosphate complexes with elongation factor Tu. (1977) (29)
- Metal-catalyzed oxidation in the presence of water in foods (1971) (29)
- Characterization of the active site structures of arginine kinase-substrate complexes. Water proton magnetic relaxation rates and electron paramagnetic resonance spectra of manganous-enzyme complexes with substrates and of a transition state analog. (1974) (28)
- Fluorine-19 nuclear magnetic resonance studies of the structure of 5-fluorouracil-substituted Escherichia coli transfer RNA. (1986) (27)
- Studies of manganous nucleotide complexes with uridine diphosphate-glucose pyrophosphorylase, formyltetrahydrofolate synthetase, and creatine kinase. Mechanism of water proton magnetic relaxation from frequency dependent measurements. (1972) (27)
- Changes in tertiary structure accompanying a single base change in transfer RNA. Proton magnetic resonance and aminoacylation studies of Escherichia coli tRNAMet f1 and tRNAMet f3 and their spin-labeled (s4U8) derivatives. (1976) (26)
- Magnetic resonance studies of the interaction of spin-labeled creatine kinase with paramagnetic manganese-substrate complexes. (1971) (25)
- Magnetic resonance studies of active sites in enzymic complexes. (1982) (24)
- The Effect of Magnesium on the Reactivity of the Essential Sulfhydryl Groups in Creatine Kinase-Substrate Complexes* (1966) (24)
- Mapping active sites of phosphoryl-transferring enzymes by magnetic resonance methods. (1972) (23)
- Reactivity and metal-dependent stereospecificity of the phosphorothioate analogs of ADP and ATP and reactivity of Cr(III)ATP in the 3-phosphoglycerate kinase reaction. Structure of the metal nucleotide substrates. (1982) (23)
- Asymmetric binding of the inhibitor di(adenosine-5') pentaphosphate (Ap5A) to adenylate kinase. (1977) (23)
- Phosphoenolpyruvate synthetase. Partial reactions studied with adenosine triphosphate analogues and the inorganic phosphate-H2 18O exchange reaction. (1970) (23)
- Magnetic resonance studies on inactivated forms of creatine kinase. (1968) (21)
- A STUDY OF THE INVERSION OF d-PHENYLAMINOBUTYRIC ACID AND THE ACETYLATION OF l-PHENYLAMINOBUTYRIC ACID BY MEANS OF THE ISOTOPES OF NITROGEN AND HYDROGEN (1939) (21)
- Spin Density in Octocyanomolybdate (V) (1957) (21)
- Reactivity and metal-dependent stereospecificity of the phosphorothioate analogs of ATP in the arginine kinase reaction. Structure of the metal-nucleoside triphosphate substrate. (1982) (20)
- Formyltetrahydrofolate synthetase. Magnetic resonance studies of the reaction. (1967) (20)
- 31P NMR quantitation of the displacement of equilibria of arginine, creatine, pyruvate, and 3-P-glycerate kinase reactions by substitution of sulfur for oxygen in the beta phosphate of ATP. (1980) (20)
- Reactions of thio analogues of adenosine 5'-triphosphate catalyzed by methionyl-tRNA synthetase from Escherichia coli and metal dependence of stereospecificity. (1982) (18)
- Photochemically induced dynamic nuclear polarization NMR study of yeast and horse muscle phosphoglycerate kinase. (1986) (18)
- Structural and Chemical Properties of ATP and Its Metal Complexes in Solution (1990) (17)
- The relation of transmethylation to anserine. (1943) (17)
- The mechanism of hydrolysis of adenosine di- and tri-phosphate catalysed by potato apyrase. (1957) (17)
- THE TRANSFER OF OXYGEN FROM ARSENATE-180 TO PHOSPHATE IN ARSENATE-STIMULATED ADENOSINE TRIPHOSPHATASE REACTIONS. (1963) (16)
- Dependence of the proton magnetic resonance spectra on the oxidation state of flavodoxin from Clostridium MP and from Peptostreptococcus elsdenii. (1973) (16)
- Beta- and gamma-thio analogues of adenosine triphosphate as probes of the Escherichia coli valyl transfer ribonucleic acid synthetase reaction pathway. A novel stereospecific interchange of adenosine 5'-O-(2-thiotriphosphate) to adenosine 5'-O-(3-thiotriphosphate). (1979) (15)
- Structural aspects of manganese-pyruvate kinase substrate and inhibitor complexes deduced from proton magnetic relaxation rates of pyruvate and a phosphoenolpyruvate analog. (1974) (15)
- The stereospecificity of enzymic interaction of diphosphopyridine nucleotide with water. (1956) (14)
- Cyclocreatine transport and cytotoxicity in rat glioma and human ovarian carcinoma cells: 31P-NMR spectroscopy. (1996) (14)
- Electron paramagnetic resonance and proton relaxation rate studies of spin-labeled creatine kinase and its complexes. (1971) (13)
- Magnetic resonance studies of interactions of spin-labeled elongation factor Tu with ligands. (1978) (12)
- Laser photo-CIDNP NMR of pyridoxal phosphate and pyridoxyllysine residues: an extrinsic probe for non-aromatic amino acid residues in proteins. (1980) (11)
- Nuclear magnetic resonance study of the binding of phosphoenolpyruvate and phosphoenol-alpha-ketobutyrate to manganese pyruvate kinase. Temperature, frequency,and monovalent cation dependence of water proton nuclear magnetic resonance relaxation rates. (1973) (11)
- Role of the beta-phosphate-gamma-phosphate interchange reaction of adenosine triphosphate in amino acid discrimination by valyl- and methionyl-tRNA synthetases from Escherichia coli. (1981) (11)
- Kinetics of cyclocreatine and Na+ cotransport in human breast cancer cells: mechanism of activity. (1999) (10)
- Magnetic resonance studies of the interaction of cupric ion with native and modified forms of ribonuclease. (1969) (10)
- 31P NMR of the reversible methionine activation reaction catalyzed by methionyl-tRNA synthetase of Escherichia coli. Equilibrium, interconversion rates, and NMR parameters of the enzyme-bound species. (1980) (10)
- Calcium transport and ATPase activities of sarcoplasmic reticulum with adenosine 5'-O-(2-thiotriphosphate) diastereomers as substrates. (1982) (9)
- THE NON-SPECIFICITY OF AMINO ACID CONFIGURATION IN MALIGNANT TISSUE HYDROLYSATES. (1940) (8)
- THE AMPHOTERIC NATURE OF THE PRESSOR PRINCIPLE OF THE POSTERIOR LOBE OF THE PITUITARY GLAND (1941) (8)
- INTERPRETATION OF NMR RELAXATION MECHANISM OF WATER PROTONS IN SOLUTIONS OF ENZYME-MANGANESE-SUBSTRATE COMPLEXES FROM TEMPERATURE DEPENDENCE OF RELAXATION RATES (1967) (8)
- A further investigation of the ability of sarcosine to serve as a labile methyl donor. (1946) (7)
- Shift of the equilibrium constant of the 3-P-glycerate kinase reaction towards 1,3-bis-P-glycerate with adenosine 5'-O-(2-thiotriphosphate) (ATP beta S) as substrate. (1980) (7)
- The effect of the dietary level of methionine on the rate of transmethylation reactions in vivo. (1946) (7)
- Some early tracer experiments with stable isotopes (1995) (7)
- Electron Paramagnetic Resonance Spectra of Manganese(II)-Protein Complexes (2002) (6)
- 1H NMR STRUCTURAL STUDIES OF A COMPLEX OF MELITTIN WITH PERDEUTERATED CALMODULIN (1987) (6)
- [37] O18 containing phosphate and related compounds (1957) (4)
- NMR studies of phosphoryl transfer reactions. (1984) (3)
- 31 P NMR Studies of Enzymatic Reactions (2007) (3)
- Combustion in a Bomb with a Fuel-Injection System (1935) (3)
- A COMPARATIVE STUDY OF ACETYLATION IN VIVO OF PHENYLAMINOBUTYRIC ACID WITH p-AMINOBENZOIC ACID AND SULFANILAMIDE (1943) (3)
- Optimization of Composite Highway Bridge Systems (1996) (3)
- Measurement of interconversion rates of bound substrates of phosphoryl transfer enzymes by (31)P nuclear magnetic resonance. (1978) (3)
- Kinetics of cyclocreatine and Na(+) cotransport in human breast cancer cells: mechanism of activity. (1999) (2)
- AN ENZYME-METAL-PHOSPHORYL BRIDGE STRUCTURE IN PYRUVATE KINASE AS DETECTED BY FLUORINE MAGNETIC RESONANCE* (1967) (2)
- Mini‐series: Significant contributions to biological chemistry over the past 125 years: Biochemistry in the United States in the first half of the twentieth century (2002) (2)
- Atomic and nuclear probes of enzyme systems. (1992) (2)
- Influence of the Structure of Transfer RNA on Its Interaction with Enzymes and Divalent Cations (1968) (2)
- The Nation’s water pollution problem—Detergent’s role in it (1963) (2)
- Magnetic resonance studies of specificity in binding and catalysis of phosphotransferases. (1975) (2)
- Some Factors Affecting Combustion in an Internal-Combustion Engine (1936) (2)
- Wildlife in Crisis (2012) (2)
- A study on transmethylation with methionine containing varying amounts of deuterium in the methyl group. (1947) (1)
- Reactivity and Metal-dependent Stereospecificity of the Phosphorothioate Analogs of ADP and ATP and Reactivity of Cr(II1)ATP in the 3-Phosphoglycerate Kinase Reaction (1982) (1)
- NARROWING OF PROTON RESONANCES OF MACROMOLECULES BY SPINNING AT AN ANGLE OF 54-7°* (1967) (1)
- Photo-induced CIDNP of nucleoside triphosphate analogs (1985) (1)
- Reversible inactivation of chymotrypsin by sulfate ions. (1960) (1)
- A Note on the Polarization of the 1934 Solar Corona (1937) (1)
- PARAMAGNETIC PROBES IN ENZYME SYSTEMS (1971) (0)
- Corrections - Magnetic Resonance Studies of the Interaction of the Manganous Ion with Bovine Serum Albumin (1964) (0)
- KINETIC AND THERMODYNAMIC ASPECTS OF ATP-DEPENDENT CA2+ TRANSPORT IN SARCOPLASMIC RETICULUM USING ATPβS DIASTEREOMERS AS SUBSTRATES (1985) (0)
- /sup 1/H-NMR studies on the interaction of calmodulin with melittin (1986) (0)
- THERMODYNAMIC FACTORS IN THE SYNTHESIS OF TWO-STRANDED NUCLEIC ACIDS (1966) (0)
- ENZYMATIC REACTIONS OF PHOSPHATE COMPOUNDS (1982) (0)
- Postdoctoral Years (2002) (0)
- From the Committee on the Status of Women : Women Faculty in the University of Pennsylvania : Part On e (2004) (0)
- 8 – Nuclear Magnetic Resonance Studies of Protein—Nucleotide Interactions (1978) (0)
- Cyclocreatine protection against adriamycin cardiomyopathy (1991) (0)
- TWO ISOTOPES ARE BETTER THAN ONE (1982) (0)
- P Nuclear Magnetic Resonance of Bound Substrates of Arginine Kinase Reaction * (2002) (0)
- Magnetic Resonance Studies of Metal-Enzyme-Substrate Interactions. (1962) (0)
- 19F NMR study of 5-fluorouridine w8 =tRNA substituted TRNA molecules in solution (1981) (0)
- Mildred Cohn: Peregrinations of an Enzymologist in NMR (2007) (0)
- Paramagnetic Probes of Kinase Mechanisms (1974) (0)
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