Eric Lander
#937
Most Influential Person Now
American biologist and academic, (1957 - ), Brooklyn, New York, USA
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Eric Landerbiology Degrees
Biology
#122
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#225
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#73
USA Rank
Computational Biology
#2
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#2
Historical Rank
#2
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Mathematical Biology
#1
World Rank
#2
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#1
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Biology
Eric Lander's Degrees
- Bachelors Mathematics Princeton University
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Why Is Eric Lander Influential?
(Suggest an Edit or Addition)Areas of Specialization: Systems Biology, Genetics
Eric Lander is founding director of the Broad Institute at the Massachusetts Institute of Technology and Harvard University, Professor of Biology at Massachusetts Institute of Technology, and Professor of Systems Biology at Harvard Medical School. He graduated from Princeton University as valedictorian, with a BS in mathematics. He went on to attend University of Oxford as a Rhodes Scholar, where he earned his PhD He is a founder of Verastem and a founding advisor of Foundation Medicine.
He began his career in mathematics, but soon started looking at mathematical applications in neurobiology. In order to make the transition, he studied cellular neurobiology and later microbiology and genetics. He founded the Whitehead Institute/MIT Center for Genome Research which quickly became one of the world’s leading genomic research centers.
He became a MacArthur Fellow in 1987, and a co-chair for the Council of Advisors on Science and Technology for the Obama Administration in 2008. He was honored with the Breakthrough Prize in Life Sciences in 2013 and with the William Allan Award of the American Society of Human Genetics in 2017. Among his most impactful contributions is his molecular taxonomy for cancer, which groups cancers based on their gene expression, and correlates that information to chemotherapy response.
Featured in Top Influential Biologists Today
According to Wikipedia, Eric Steven Lander is an American mathematician and geneticist who is a professor of biology at the Massachusetts Institute of Technology , and a professor of systems biology at Harvard Medical School. Eric Lander is founding director emeritus of the Broad Institute of MIT and Harvard. He is a 1987 MacArthur Fellow and Rhodes Scholar.
Eric Lander's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles (2005) (33800)
- Initial sequencing and analysis of the human genome. (2001) (15222)
- Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. (1999) (12024)
- A global reference for human genetic variation (2015) (11857)
- Integrative Genomics Viewer (2011) (10276)
- An integrated map of genetic variation from 1,092 human genomes (2012) (7565)
- MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations. (1987) (6873)
- PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes (2003) (6859)
- Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome (2009) (6558)
- Integrated Genomic Analyses of Ovarian Carcinoma (2011) (6411)
- Comprehensive molecular characterization of human colon and rectal cancer (2012) (6141)
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways (2008) (5775)
- The Structure of Haplotype Blocks in the Human Genome (2002) (5687)
- Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results (1995) (5416)
- Mapping mendelian factors underlying quantitative traits using RFLP linkage maps. (1989) (5316)
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (2007) (5196)
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping (2014) (5193)
- A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells (2006) (5120)
- Initial sequencing and comparative analysis of the mouse genome. (2002) (4609)
- Comprehensive molecular characterization of gastric adenocarcinoma (2014) (4496)
- The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease (2006) (4224)
- Development and Applications of CRISPR-Cas9 for Genome Engineering (2014) (4182)
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cells (2007) (4164)
- Comprehensive molecular profiling of lung adenocarcinoma (2014) (4095)
- Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals (2009) (3820)
- Integrated genomic characterization of endometrial carcinoma (2013) (3708)
- The Somatic Genomic Landscape of Glioblastoma (2013) (3693)
- Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples (2013) (3663)
- A Draft Sequence of the Neandertal Genome (2010) (3419)
- The landscape of somatic copy-number alteration across human cancers (2010) (3297)
- Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. (1999) (3275)
- Parametric and nonparametric linkage analysis: a unified multipoint approach. (1996) (3023)
- Comprehensive genomic characterization of squamous cell lung cancers (2012) (2998)
- A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms (2001) (2879)
- Comprehensive genomic characterization of head and neck squamous cell carcinomas (2015) (2860)
- Mutational heterogeneity in cancer and the search for new cancer-associated genes (2013) (2852)
- Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression (2009) (2770)
- Finishing the euchromatic sequence of the human genome (2004) (2770)
- Mutational heterogeneity in cancer and the search for new cancer genes (2013) (2691)
- Somatic mutations affect key pathways in lung adenocarcinoma (2008) (2640)
- Gene expression correlates of clinical prostate cancer behavior. (2002) (2549)
- Discovery and saturation analysis of cancer genes across 21 tumor types (2014) (2530)
- Genome-scale DNA methylation maps of pluripotent and differentiated cells (2008) (2515)
- A molecular signature of metastasis in primary solid tumors (2003) (2476)
- Genome sequence, comparative analysis and haplotype structure of the domestic dog (2005) (2448)
- Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning (2002) (2443)
- Prediction of central nervous system embryonal tumour outcome based on gene expression (2002) (2421)
- Genetic Screens in Human Cells Using the CRISPR-Cas9 System (2013) (2407)
- Transcriptional regulatory code of a eukaryotic genome (2004) (2362)
- Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. (2014) (2344)
- Reactive oxygen species have a causal role in multiple forms of insulin resistance (2006) (2304)
- The Mutational Landscape of Head and Neck Squamous Cell Carcinoma (2011) (2301)
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 (2009) (2300)
- Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening (2009) (2280)
- Detecting Novel Associations in Large Data Sets (2011) (2257)
- A Landscape of Driver Mutations in Melanoma (2012) (2244)
- Initial sequence of the chimpanzee genome and comparison with the human genome (2005) (2222)
- Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. (2015) (2211)
- The ENCODE (ENCyclopedia Of DNA Elements) Project (2004) (2194)
- Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. (1998) (2194)
- Genomic Classification of Cutaneous Melanoma (2015) (2143)
- The Molecular Taxonomy of Primary Prostate Cancer (2015) (2116)
- Multiclass cancer diagnosis using tumor gene expression signatures (2001) (2107)
- The Mammalian Epigenome (2007) (2072)
- Integrated Genomic Characterization of Papillary Thyroid Carcinoma (2014) (2007)
- Evolution of genes and genomes on the Drosophila phylogeny (2007) (1992)
- Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease (2003) (1984)
- Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals (2005) (1975)
- A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response (2010) (1942)
- Sequencing and comparison of yeast species to identify genes and regulatory elements (2003) (1920)
- Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype (2004) (1905)
- International network of cancer genome projects (2010) (1839)
- Detecting recent positive selection in the human genome from haplotype structure (2002) (1838)
- lincRNAs act in the circuitry controlling pluripotency and differentiation (2011) (1827)
- An immunogenic personal neoantigen vaccine for patients with melanoma (2017) (1820)
- High-resolution haplotype structure in the human genome (2001) (1798)
- Linkage disequilibrium in the human genome (2001) (1756)
- A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen (2006) (1749)
- Comprehensive molecular characterization of urothelial bladder carcinoma (2014) (1748)
- Comprehensive molecular characterization of clear cell renal cell carcinoma (2013) (1724)
- Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations (2018) (1716)
- The NIH Roadmap Epigenomics Mapping Consortium (2010) (1680)
- The genome sequence of the filamentous fungus Neurospora crassa (2003) (1654)
- Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing (2012) (1620)
- Absolute quantification of somatic DNA alterations in human cancer (2012) (1607)
- Dissecting the Regulatory Circuitry of a Eukaryotic Genome (1998) (1585)
- Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse (2005) (1564)
- High-quality draft assemblies of mammalian genomes from massively parallel sequence data (2010) (1563)
- The genomic basis of adaptive evolution in threespine sticklebacks (2012) (1560)
- Genome-wide detection and characterization of positive selection in human populations (2007) (1558)
- Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms (1988) (1551)
- Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs (2002) (1543)
- Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses (2001) (1518)
- Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae (2004) (1510)
- MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia (2002) (1509)
- Genomic analysis of metastasis reveals an essential role for RhoC (2000) (1508)
- The mystery of missing heritability: Genetic interactions create phantom heritability (2012) (1478)
- Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. (2008) (1431)
- Genetic Mapping in Human Disease (2008) (1425)
- Construction of multilocus genetic linkage maps in humans. (1987) (1424)
- Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. (2001) (1413)
- Remodeling of yeast genome expression in response to environmental changes. (2001) (1412)
- Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments. (2016) (1405)
- Solution Hybrid Selection with Ultra-long Oligonucleotides for Massively Parallel Targeted Sequencing (2009) (1393)
- Initial genome sequencing and analysis of multiple myeloma (2011) (1385)
- Risk alleles for multiple sclerosis identified by a genomewide study. (2007) (1380)
- A polygenic burden of rare disruptive mutations in schizophrenia (2014) (1371)
- Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer (2012) (1367)
- C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector (2016) (1335)
- Development and Applications of CRISPR-Cas 9 for Genome Engineering (2015) (1318)
- Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia (2012) (1297)
- The Human Cell Atlas (2017) (1285)
- On the allelic spectrum of human disease. (2001) (1265)
- Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes (2015) (1265)
- Identification and characterization of essential genes in the human genome (2015) (1248)
- Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs (2010) (1233)
- The New Genomics: Global Views of Biology (1996) (1208)
- The genomic complexity of primary human prostate cancer (2010) (1195)
- The common PPARγ Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes (2000) (1150)
- Lessons from the Cancer Genome (2013) (1147)
- A genetic map of the mouse suitable for typing intraspecific crosses. (1992) (1142)
- Cohesin Loss Eliminates All Loop Domains (2017) (1140)
- Sequence analysis of mutations and translocations across breast cancer subtypes (2012) (1133)
- Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak (2014) (1126)
- Characterizing the cancer genome in lung adenocarcinoma (2007) (1122)
- RNA targeting with CRISPR–Cas13 (2017) (1116)
- Punctuated Evolution of Prostate Cancer Genomes (2013) (1105)
- Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. (2002) (1105)
- SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. (2011) (1098)
- Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma. (2017) (1092)
- A high-resolution map of human evolutionary constraint using 29 mammals (2011) (1081)
- A Gene Map of the Human Genome (1996) (1080)
- Positive Natural Selection in the Human Lineage (2006) (1070)
- Dissecting direct reprogramming through integrative genomic analysis (2008) (1058)
- Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma (2007) (1052)
- Initial impact of the sequencing of the human genome (2011) (1041)
- Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis (2005) (1014)
- Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains (2008) (1010)
- Complete multipoint sib-pair analysis of qualitative and quantitative traits. (1995) (980)
- The genetic landscape of high-risk neuroblastoma (2013) (938)
- Genomic mapping by fingerprinting random clones: a mathematical analysis. (1988) (935)
- Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing (2012) (932)
- Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes (2010) (932)
- Homozygosity mapping: a way to map human recessive traits with the DNA of inbred children. (1987) (931)
- The genetic architecture of type 2 diabetes (2016) (927)
- Mendelian factors underlying quantitative traits in tomato: comparison across species, generations, and environments. (1991) (922)
- Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells (2010) (921)
- Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens (2016) (920)
- Local regulation of gene expression by lncRNA promoters, transcription and splicing (2016) (900)
- ALLPATHS: de novo assembly of whole-genome shotgun microreads. (2008) (891)
- A genetic linkage map of the human genome (1987) (882)
- The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome (2013) (866)
- Integrated Analysis of Protein Composition, Tissue Diversity, and Gene Regulation in Mouse Mitochondria (2003) (857)
- Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. (2000) (855)
- Identification of genetic factors contributing to heterosis in a hybrid from two elite maize inbred lines using molecular markers. (1992) (850)
- De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds (2017) (837)
- Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. (2014) (836)
- Mutations driving CLL and their evolution in progression and relapse (2015) (830)
- Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease (2001) (820)
- Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom. (2016) (820)
- An STS-Based Map of the Human Genome (1995) (818)
- The genomic substrate for adaptive radiation in African cichlid fish (2014) (811)
- The plasticity of dendritic cell responses to pathogens and their components. (2001) (809)
- Assessing the impact of population stratification on genetic association studies (2004) (806)
- Ab initio reconstruction of transcriptomes of pluripotent and lineage committed cells reveals gene structures of thousands of lincRNAs (2010) (779)
- The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. (2000) (763)
- The diastrophic dysplasia gene encodes a novel sulfate transporter: Positional cloning by fine-structure linkage disequilibrium mapping (1994) (758)
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (754)
- Genetic dissection of complex traits science (1994) (750)
- Human macrophage activation programs induced by bacterial pathogens (2002) (749)
- An SNP map of the human genome generated by reduced representation shotgun sequencing (2000) (749)
- Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat (1991) (738)
- Genome Sequence, Comparative Analysis, and Population Genetics of the Domestic Horse (2009) (732)
- Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. (2015) (727)
- Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences (2007) (715)
- Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation (2001) (713)
- Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse (1993) (701)
- Exome and whole genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity (2013) (700)
- Melanoma genome sequencing reveals frequent PREX2 mutations (2012) (695)
- ARACHNE: a whole-genome shotgun assembler. (2002) (686)
- Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability (2015) (684)
- Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA (2014) (679)
- A physical map of 30,000 human genes. (1998) (670)
- Chemosensitivity prediction by transcriptional profiling (2001) (663)
- Ribosome Profiling Provides Evidence that Large Noncoding RNAs Do Not Encode Proteins (2013) (662)
- Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy (2010) (653)
- Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. (2016) (630)
- Ploidy regulation of gene expression. (1999) (625)
- Chromatin modifying enzymes as modulators of reprogramming (2012) (621)
- Distinguishing protein-coding and noncoding genes in the human genome (2007) (616)
- A comprehensive genetic map of the mouse genome (1996) (615)
- Errα and Gabpa/b specify PGC-1α-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle (2004) (614)
- Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene (2007) (613)
- Array of hope (1999) (601)
- Linkage disequilibrium mapping in isolated founder populations: diastrophic dysplasia in Finland (1992) (584)
- Characterization of single-nucleotide polymorphisms in coding regions of human genes (1999) (581)
- Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics (2003) (574)
- The genome of M. acetivorans reveals extensive metabolic and physiological diversity. (2002) (573)
- The genome of the green anole lizard and a comparative analysis with birds and mammals (2011) (573)
- A genetic map of the mouse with 4,006 simple sequence length polymorphisms (1994) (571)
- Searching for missing heritability: Designing rare variant association studies (2014) (564)
- The African coelacanth genome provides insights into tetrapod evolution (2013) (563)
- Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus (2002) (562)
- The Xist lncRNA directly interacts with SHARP to silence transcription through HDAC3 (2015) (553)
- Highly parallel identification of essential genes in cancer cells (2008) (553)
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells (2011) (543)
- High-resolution mapping of copy-number alterations with massively parallel sequencing (2009) (540)
- Identification and Classification of Conserved RNA Secondary Structures in the Human Genome (2006) (538)
- Genetic evidence for complex speciation of humans and chimpanzees (2006) (537)
- Dissecting direct reprogramming through integrative genomic analysis (2008) (534)
- Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. (2000) (532)
- Efficient mapping of mendelian traits in dogs through genome-wide association (2007) (525)
- High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis (2013) (512)
- AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. (2009) (510)
- A comprehensive genetic map of the mouse genome (1996) (497)
- A genetic linkage map of the laboratory rat, Rattus norvegicus (1995) (494)
- Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida (2006) (494)
- Topological organization of multichromosomal regions by the long intergenic noncoding RNA Firre (2014) (491)
- Comparative Epigenomic Analysis of Murine and Human Adipogenesis (2010) (488)
- A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection (2010) (488)
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping (2015) (480)
- The mosaic structure of variation in the laboratory mouse genome (2002) (476)
- Characterization of single-nucleotide polymorphisms in coding regions of human genes (1999) (467)
- Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes (1999) (466)
- Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras (2017) (465)
- Analysing complex genetic traits with chromosome substitution strains (2000) (457)
- Anteroposterior Patterning in Hemichordates and the Origins of the Chordate Nervous System (2003) (450)
- Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse (2000) (438)
- Disruption of the nuclear hormone receptor RORα in staggerer mice (1996) (436)
- Systematic mapping of functional enhancer–promoter connections with CRISPR interference (2016) (431)
- Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction (2014) (426)
- Abnormal gene expression in cloned mice derived from embryonic stem cell and cumulus cell nuclei (2002) (419)
- Activity-by-Contact model of enhancer-promoter regulation from thousands of CRISPR perturbations (2019) (415)
- Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast (1999) (414)
- Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer (2011) (412)
- Human and mouse gene structure: comparative analysis and application to exon prediction (2000) (412)
- Restriction fragment length polymorphism linkage map for Arabidopsis thaliana. (1988) (410)
- Detection of regulatory variation in mouse genes (2002) (409)
- Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells (2013) (409)
- Discovery and characterization of artifactual mutations in deep coverage targeted capture sequencing data due to oxidative DNA damage during sample preparation (2013) (404)
- RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites (2014) (400)
- Determination of ancestral alleles for human single-nucleotide polymorphisms using high-density oligonucleotide arrays (1999) (399)
- Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma (2016) (396)
- Genome-scale loss-of-function screening with a lentiviral RNAi library (2006) (396)
- A structural variation reference for medical and population genetics (2020) (394)
- Hi-C: A Method to Study the Three-dimensional Architecture of Genomes. (2010) (392)
- Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood (2019) (391)
- ARSACS, a spastic ataxia common in northeastern Québec, is caused by mutations in a new gene encoding an 11.5-kb ORF (2000) (389)
- Genomic Analysis Identifies Targets of Convergent Positive Selection in Drug Resistant Mycobacterium tuberculosis (2013) (380)
- Symmetric Designs: An Algebraic Approach (1983) (379)
- The Heroes of CRISPR (2016) (377)
- Patterns of somatic structural variation in human cancer genomes (2020) (377)
- Mutations in the human Delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis (2000) (375)
- Genome-Wide Search for Asthma Susceptibility Loci in a Founder Population (1998) (374)
- RNF43 is frequently mutated in colorectal and endometrial cancers (2014) (371)
- Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle. (2004) (368)
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells (2011) (367)
- A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer (2017) (365)
- Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice (2004) (359)
- Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. (2011) (356)
- Systematic detection of errors in genetic linkage data. (1992) (355)
- Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma (2016) (353)
- A nonparametric approach for mapping quantitative trait loci. (1995) (350)
- Whole-genome sequence assembly for mammalian genomes: Arachne 2. (2003) (348)
- Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites (2007) (345)
- Identifying Recent Adaptations in Large-Scale Genomic Data (2013) (343)
- Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families (1996) (342)
- Sequencing the nuclear genome of the extinct woolly mammoth (2008) (342)
- A Second Fatty Acid Amide Hydrolase with Variable Distribution among Placental Mammals* (2006) (339)
- Whole-exome sequencing and clinical interpretation of formalin-fixed , paraffin-embedded tumor samples to guide precision cancer medicine (2014) (339)
- Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma (2014) (335)
- Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis (1997) (326)
- Human genome sequence variation and the influence of gene history, mutation and recombination (2002) (325)
- A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients (2017) (324)
- Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution (2006) (322)
- Genomewide scan of multiple sclerosis in Finnish multiplex families. (1997) (321)
- Direct Identification of Hundreds of Expression-Modulating Variants using a Multiplexed Reporter Assay (2016) (319)
- Genome-scale DNA methylation mapping of clinical samples at single-nucleotide resolution (2010) (319)
- Rabbit genome analysis reveals a polygenic basis for phenotypic change during domestication (2014) (319)
- New models of collaboration in genome-wide association studies: the Genetic Association Information Network (2007) (313)
- A genome-wide map of diversity in Plasmodium falciparum (2007) (311)
- Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. (2004) (310)
- Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood (2017) (309)
- A high-density screen for linkage in multiple sclerosis. (2005) (308)
- Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution (2015) (307)
- Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays (2000) (307)
- Genetic Mechanisms of Immune Evasion in Colorectal Cancer. (2018) (305)
- Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia. (2014) (302)
- Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion (2011) (298)
- CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis (1998) (296)
- Ducky Mouse Phenotype of Epilepsy and Ataxia Is Associated with Mutations in the Cacna2d2 Gene and Decreased Calcium Channel Current in Cerebellar Purkinje Cells (2001) (295)
- Quality scores and SNP detection in sequencing-by-synthesis systems. (2008) (294)
- 28-way vertebrate alignment and conservation track in the UCSC Genome Browser. (2007) (293)
- Molecular classification of multiple tumor types (2001) (291)
- Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition (2013) (291)
- The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries (1998) (291)
- Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. (2012) (290)
- Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming (2019) (290)
- Locally disordered methylation forms the basis of intratumor methylome variation in chronic lymphocytic leukemia. (2014) (289)
- Inactivating mutations in NPC1L1 and protection from coronary heart disease. (2014) (289)
- Integrative analysis of the melanoma transcriptome. (2010) (288)
- Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice (1995) (281)
- Paired Exome Analysis of Barrett’s Esophagus and Adenocarcinoma (2015) (281)
- Rapid dissection and model-based optimization of inducible enhancers in human cells using a massively parallel reporter assay (2012) (279)
- ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. (2017) (278)
- Whole-exome sequencing and clinical interpretation of FFPE tumor samples to guide precision cancer medicine (2013) (275)
- Adopt a moratorium on heritable genome editing (2019) (274)
- Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis (2008) (273)
- Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat (1996) (271)
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- Neighborhood regulation by lncRNA promoters, transcription, and splicing (2016) (12)
- Phylogenetically and spatially conserved word pairs associated with gene expression changes in yeasts (2003) (12)
- Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells (2011) (11)
- Gene Expression Analysis Using Clustering (2009) (11)
- Gene Expression Analysis Using Clustering (2009) (11)
- Delivery mode impacts newborn gut colonization efficiency (2020) (11)
- A dictionary-based approach for gene annotation. (1999) (11)
- Genome-Wide CRISPR/Cas9 Screening for Identification of Cancer Genes in Cell Lines. (2018) (11)
- Pet Ownership and Cancer Risk in the Women's Health Initiative (2016) (11)
- Prospects for the genetic analysis of schizophrenia. (1989) (11)
- New mutations, old statistical challenges (2017) (10)
- Author response: The Human Cell Atlas (2017) (10)
- ANGPTL 3 De fi ciency and Protection Against Coronary Artery Disease (2017) (10)
- correction: Genomic analysis of metastasis reveals an essential role for RhoC (2001) (10)
- The Accelerator (2011) (10)
- Composite measurements and molecular compressed sensing for highly efficient transcriptomics (2017) (10)
- The distribution of clusters in random graphs (1990) (10)
- A genetic linkage map of the mouse: current applications and future prospects [see comments] (1993) (9)
- Patterson et al. reply (2008) (9)
- Perturbation of m 6 A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5 Sites Citation (2014) (9)
- Diabetes, dependence, asymptotics, selection and significance (1997) (8)
- Gene-based anchoring of the rat genetic linkage and cytogenetic maps. (1999) (8)
- Compressed sensing for imaging transcriptomics (2019) (8)
- Sequencing the Genome of the Domestic Dog Canis familiaris (2002) (8)
- Recent Developments in Computational Gene Recognition (1998) (7)
- Counting algorithms for linkage: correction to Morton and Collins (1991) (7)
- Corrigendum: Genetic dissection of autoimmune type I diabetes in the BB rat (1994) (7)
- Genomics: launching a revolution in medicine. (2000) (7)
- Juicebox Provides a Visualization System for HiC Contact Maps with Unlimited Zoom Citation (2016) (7)
- LB-11. Comparison of Viral Loads in Individuals With or Without Symptoms At Time of COVID-19 Testing Among 32,480 Residents and Staff of Nursing Homes and Assisted Living Facilities in Massachusetts (2020) (6)
- Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial (2014) (6)
- Mouse mammary tumor virusyv-Ha-ras transgene-induced mammary tumors exhibit strain-specific allelic loss on mouse chromosome 4 (allelotypeyloss of heterozygosityytumor suppressor geneytransgenic miceyexperimental breast neoplasms) (1997) (6)
- Transcript identification on the CLN5 region on chromosome 13q22 (1999) (6)
- Competition between and within teams : The Lifeboat Principle (1989) (6)
- Gain-of-Function Claims for Type-2-Diabetes-Associated Coding Variants in SLC16A11 Are Not Supported by the Experimental Data. (2019) (6)
- 0355 in Plasmodium falciparum (2011) (6)
- Scientific Commentary: The Scientific Foundations and Medical and Social Prospects of the Human Genome Project (1998) (6)
- An automated method for DNA preparation from thousands of YAC clones. (1991) (6)
- Comprehensive molecular characterization of colorectal cancer reveals genomic predictors of immune cell infiltrates. (2015) (6)
- Sequencing the Genome of the Domestic Cat Felis catus (2002) (5)
- Novel Germline Genetic Variants Associated with Familial Chronic Lymphocytic Leukemia (CLL) (2011) (5)
- Construction of a large-insert yeast artificial chromosome library of the rat genome (2009) (5)
- A comprehensive large-insert yeast artificial chromosome library for physical mapping of the mouse genome (1996) (5)
- Genetic mapping in hypertension. (1992) (5)
- Quantitative Clonal Dynamics Define Mechanisms of CLL Evolution in Response to Combination Chemotherapy (2015) (5)
- Consanguinity and heterogeneity: cystic fibrosis need not be homogeneous in Italy. (1986) (5)
- Calculating the Secrets of Life (1995) (5)
- Compatibility logic of human enhancer and promoter sequences (2021) (5)
- Symmetric Designs and Self‐Dual Codes (1981) (5)
- Erez Lieberman-Aiden Principles of the Human Genome Comprehensive Mapping of Long-Range Interactions Reveals Folding (2012) (4)
- Increased Local Disorder of DNA Methylation Forms the Basis of High Intra-Leukemic Epigenetic Heterogeneity and Enhances CLL Evolution (2013) (4)
- application to hematopoietic differentiation Interpreting patterns of gene expression with self-organizing maps: Methods and (2007) (4)
- Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls (2018) (4)
- Restrictions upon multipliers of an abelian difference set (1988) (4)
- Novel Putative Driver Gene Mutations in Chronic Lymphocytic Leukemia (CLL): Results from a Combined Analysis of Whole-Exome Sequencing of 262 Primary CLL Samples (2014) (4)
- Iterative template refinement: protein-fold prediction using iterative search and hybrid sequence/structure templates. (1996) (4)
- Count me in: A patient-driven research initiative to accelerate cancer research. (2018) (4)
- The Angiosarcoma Project: Generating the genomic landscape of a rare cancer through a direct-to-patient initiative. (2017) (4)
- Erratum: Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood (2017) (4)
- Cyclin D 3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number Citation (2012) (3)
- CK1e Is Required for Breast Cancers Dependent on b- Catenin Activity (2017) (3)
- Biology as Information (2005) (3)
- Reply to Guy et al.: Support for a bottleneck in the 2011 Escherichia coli O104:H4 outbreak in Germany (2012) (3)
- Eric S. Lander (2004) (3)
- Systematic Identification of Personal Mutated Tumor-Specific Neoantigens in CLL (2012) (3)
- Brief for Amicus Curiae Eric S. Lander in Support of Neither Party (2013) (3)
- Inferring gene regulation from stochastic transcriptional variation across single cells at steady state (2022) (3)
- Contribution of HLA class II genes to susceptibility to ulcerative colitis (UC) in a Canadian inflammatory bowel disease (IBD) population (1998) (3)
- Abstract 5631: Personal neoantigen-targeting vaccination generates neoepitope-specific T cell responses in tumors of patients with glioblastoma (2018) (3)
- Reply to "Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population" and "Genetic background is an important determinant of metastatic potential" (2003) (3)
- Golub , Monitoring and Class Prediction by Gene Expression Molecular Classification of Cancer : Class Discovery (2007) (3)
- Author Correction: A structural variation reference for medical and population genetics (2021) (3)
- Supplementary Table 10 (2014) (3)
- Improved Imputation Accuracy of Rare and Low-Frequency Genetic Variants Using Population-Specific High-Coverage Whole-Genome Sequencing Data Based Imputation Reference Panel (2016) (2)
- Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features (2020) (2)
- Corrigendum: DNA sequence and analysis of human chromosome 18 (2005) (2)
- Large-Scale Single-Guide RNA Library Construction and Use for Genetic Screens: CRISPR/Cas9-based Genetic Screens (2016) (2)
- Characterizing symmetric designs by their symmetries (1988) (2)
- Large-scale chemical-genetics yields new Mycobacterium tuberculosis inhibitor classes (2018) (2)
- The Hi-Culfite assay reveals relationships between chromatin contacts and DNA methylation state (2018) (2)
- Mapping Heredity : Using Probabilistic Models and Algorithms to Map Genes and Genomes (1995) (2)
- Abstract 5371: The Metastatic Breast Cancer Project: Partnering with patients to accelerate progress in cancer research (2018) (2)
- Haplotype structure and linkage disequilibrium in 26 worldwide populations. (2002) (2)
- Correction: Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation (2019) (2)
- Genes and genomes. (1997) (2)
- Abstract B085: High mutation burden and response to immune checkpoint inhibitors in angiosarcomas of the scalp and face (2019) (2)
- High-resolution mapping reveals a conserved , widespread , dynamic meiotically regulated mRNA methylation program (2014) (2)
- Cross-sectional assessment of SARS-CoV-2 viral load by symptom status in Massachusetts congregate living facilities (2021) (2)
- Multipoint linkage analysis of the cystic fibrosis region. (1989) (2)
- The Metastatic Prostate Cancer project (MPCproject): Translational genomics through direct patient engagement. (2018) (2)
- Discovery of cancer driver genes based on nucleotide context (2018) (2)
- Reply to Lee: Downward bias in heritability estimation is not due to simplified linkage equilibrium SNP simulation (2015) (2)
- Paraneoplastic Leukemoid Reaction Associated with Increased Levels of and Tumor Overexpression of Receptors for G-CSF, GM-CSF, and IL-6: A Clinico-Pathological-Molecular Study (2018) (2)
- Large-Scale CLL Genome Analysis Reveals Novel Cancer Genes, Including SF3B1 (2011) (1)
- Abstract #3822: PDK1-SGK3 signaling in the absence of AKT activation in PIK3CA- mutant cancers (2009) (1)
- What can studies on Turner syndrome tell us about the role of X-linked genes in social cognition? (2004) (1)
- Using Dynamic Work Design to Help Cure Cancer ( and other diseases ) (2016) (1)
- In Wake of Genetic Revolution, Questions About Its Meaning (2000) (1)
- Correction: Dorsoventral Patterning in Hemichordates: Insights into Early Chordate Evolution (2015) (1)
- Sequencing the Chimpanzee Genome (2002) (1)
- Grand challenges of computational science (panel session) (1990) (1)
- Applying CRISPR-based genetic screens to identify drivers of tumor-cell sensitivity towards NK-cell attack (2019) (1)
- The Xist lncRNA interacts with SHARP to silence transcription through HDAC3 (2015) (1)
- Shifts in Intra-Clonal Dynamics Rather Than Novel Mutations Are the Main Engine Driving Tumor Evolution in Relapsed CLL (2011) (1)
- Construction of a large-insert yeast artificial chromosome library of the rat genome (2009) (1)
- Integrative analysis of the melanoma transcriptome Material Supplemental (2010) (1)
- New inhibitors of Mycobacterium tuberculosis identified using systems chemical biology (2018) (1)
- Type-I (insulin-dependent) and type-II (non-insulin-dependent) diabetes mellitus in BC1[(NODxMus spretus)F1xNOD] mice (1994) (1)
- Abstract 4017: Dissecting the clonal hierarchy of cancer-driving genomic lesions. (2013) (1)
- A patient-driven clinicogenomic partnership through the Metastatic Prostate Cancer Project (2021) (1)
- A phase II trial of atezolizumab (anti-PD-L1) with carboplatin in patients with metastatic triple-negative breast cancer (mTNBC). (2020) (1)
- Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease (2022) (1)
- Rapid Publication Characterization of the MODY 3 Phenotype Early-Onset Diabetes Caused by an Insulin Secretion Defect (2018) (1)
- Supplementary Material 10 (2014) (1)
- Fixing Rule 702: The PCAST Report and Steps to Ensure the Reliability of Forensic Feature-Comparison Methods in the Criminal Courts (2018) (1)
- Colon cancer-derived oncogenic EGFR G 724 S mutant (2014) (1)
- Discovery of the First Pathogenic Human EPO Mutation Provides Mechanistic Insight into Cytokine Signaling (2016) (1)
- Complex speciation of humans and chimpanzees Arising from : (2008) (1)
- Abstract 5384: The Angiosarcoma Project: Generating the genomic landscape of an exceedingly rare cancer through a nationwide patient-driven initiative (2018) (1)
- Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab (2014) (1)
- Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis (2021) (1)
- Human Genome Interactions Reveals Folding Principles of the Comprehensive Mapping of Long-Range (2009) (1)
- Comment: Obama adviser weighs ‘the rightful place of science’ (2010) (1)
- Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies (2022) (1)
- Correction: Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers (2015) (1)
- Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics (2021) (1)
- Type 2 Diabetes‐Associated Variants Disrupt Function of SLC16A11, a Proton‐Coupled Monocarboxylate Transporter, Through Two Distinct Mechanisms (2017) (1)
- QnAs with Eric S. Lander. Interview by Prashant Nair. (2011) (1)
- Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease (2022) (1)
- Riding the DNA railroad (2000) (1)
- Abstract P1-05-13: The metastatic breast cancer project: Translational genomics through direct patient engagement (2017) (1)
- Defining the transcriptome of nine vertebrate genomes using RNAseq (2010) (1)
- Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B (2013) (1)
- Abstract 1682: Uncovering signals of somatic selection through whole exome and whole genome sequencing of lung adenocarcinoma (2012) (1)
- ANGPTL3 De fi ciency and Protection Against Coronary Artery Disease (1)
- Verfahren zur Erkennung und Verwendung von auf Krebsstammzellen abzielenden Mitteln (2009) (0)
- Abstract 143: A platform for deep evolutionary profiling of cancer resistance (2023) (0)
- Quantitative trait locus mapping of airway responsiveness to chromosomes 6 and 7 in inbred mice. (1999) (0)
- The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research (2020) (0)
- Preview : Published ahead of advance online publication Rare germline variants in ATM are associated with chronic lymphocytic leukemia (2017) (0)
- The rat genetic and cytogenetic maps (2000) (0)
- Figure 7, Heat Map Comparisons of Differential Gene Expression by Salinomycin (2014) (0)
- Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (2020) (0)
- Abstract B016: Quantifying and dissecting pancreatic cancer cell phenotypic plasticity using lineage tracing, single-cell multiomics and CRISPR perturbations reveals novel regulators of plastic states (2022) (0)
- Map of the Laboratory Rat A High-Density Integrated Genetic Linkage and Radiation Hybrid (1999) (0)
- Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation (vol 25, pg 1859, 2018) (2020) (0)
- Figure 1, Stability Data for the Probe (ML243) in PBS Buffer (pH 7.4, 23°C) Plus Acetonitrile over 48 Hours (2013) (0)
- Characterization of biplanes by their automorphism groups (1981) (0)
- Abstract 4601: Punctuated evolution of prostate cancer genomes. (2013) (0)
- GeneticDissection ofComplex Traits (2016) (0)
- Identification of two novel susceptibility loci in a Canadian inflammatory bowel disease population (2000) (0)
- Abstract IA4: Linking RNA to human health and disease (2012) (0)
- Ciona savignyi Assembly of polymorphic genomes : Algorithms and application to data (2005) (0)
- Chinese scientists and US leadership in the life sciences (2019) (0)
- Genome-wide Association Study Identifies Shared Risk Loci Common to Two Malignancies in Golden Retrievers Citation Tonomura (2015) (0)
- Proposal for Construction of an Aplysia californica BAC Library (2003) (0)
- Sharing Costs: The Sydvattan Co. (1984) (0)
- Reconstitution of the L . shahii C 2 c 2 locus in Escherichia coli confers RNA-guided immunity (2016) (0)
- Abstract 5056: A glimpse into the somatic mutation landscape of melanoma through exome sequencing of 121 tumor-normal pairs (2012) (0)
- Breast epithelial differentiation is altered in BRCA1mut/+ carriers prior to the onset of cancer and contributes to the basal tumor phenotype. (2009) (0)
- Author Correction: Patterns of somatic structural variation in human cancer genomes (2020) (0)
- Protocol 1 : Single-Guide Library Design and Construction (2016) (0)
- Symmetric Designs: Bilinear and Quadratic Forms (1983) (0)
- Improvement of the Dog Genome to Near Finished Quality (2005) (0)
- Symmetric Designs: Representation Theory (1983) (0)
- Effect of diagnostic misclassification on the ability to detect linkage in inflammatory bowel disease (IBD) (2000) (0)
- Table 2, SAR of the Amide (2014) (0)
- 7.012 Introduction to Biology, Fall 2001 (2001) (0)
- Supplementary Table 3 (2015) (0)
- Resource Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming Graphical (0)
- Ol.data Gene Expression and Clinical Information of Two Cancer Studies (2010) (0)
- Deep-coverage whole genome sequences and blood lipids among 16,324 individuals (2018) (0)
- Wang , the Human Genome Genotyping of Single-Nucleotide Polymorphisms in Large-Scale Identification , Mapping (2007) (0)
- Saturday, 5/20, Trianon Ballroom, 1:00 pm–3:00 pmTheme I: Blood Pressure and Volume Regulation by the KidneyHYPERTENSION ASSOCIATED RENAL FAILURE IN THE FAWN-HOODED RAT IS THE RESULT OF A GENETIC PREDISPOSITION (1995) (0)
- Signal transduction, cancer classification and genetic variation (1999) (0)
- Figure 3, Dose Inhibition Assay of HMLE_shGFP, HMLE_shECad, and HMLE_shTwist by the Probe (ML243) (2013) (0)
- 15. Brave New Genome (2019) (0)
- Table 1, Comparison of the Probe (ML239) to Project Criteria (2013) (0)
- 2 First paper : Inferring the Mode of Speciation from Genomic Data : A Study of the Great Apes 2 (2006) (0)
- From Genomes to Populations: Relevance to Human Genetic Diseases (2000) (0)
- Abstract 18321: Analysis of a Consanguineous Cohort to Identify and Characterize Human Knockouts (2015) (0)
- Symmetric Designs: Invariant Factors (1983) (0)
- Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes (2021) (0)
- Integrated genomic characterization of oesophageal carcinoma (2017) (0)
- Vaccines Getting Personal with Neoantigen-Based Therapeutic Cancer (2013) (0)
- Figure 4, Dose-dependent Activity of Select Analogs in the Primary Assay (2014) (0)
- Symmetric Designs: P-adic Numbers (1983) (0)
- Pull for Knowledge Work (2018) (0)
- Adopt a moratorium on heritable genome editing (2019) (0)
- Abstract 16514: Interpretation of Whole Genome Sequences for Risk of Early-Onset Myocardial Infarction (2017) (0)
- Neafsey African Malaria Vector Mosquitoes SNP Genotyping Defines Complex Gene-Flow Boundaries Among (2014) (0)
- Table 2, Data from Additional Assays (2013) (0)
- Abstract PL07-01: Molecular profiling of breast cancer in Mexico: Identification of novel therapeutic targets through whole genome sequencing analysis. (2012) (0)
- Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability (2018) (0)
- Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes (2019) (0)
- Local regulation of gene expression by 1 lncRNA promoters , transcription , and splicing 2 3 4 (2016) (0)
- Mapping the convergence of genes for coronary artery disease onto endothelial cell programs (2022) (0)
- 2018 William Allan Award: Discovering the Genes for Common Disease: From Families to Populations. (2019) (0)
- Haplotype Block Detection Using Cira Pattern Discovery (2003) (0)
- Annual review of genomics and human genetics (2000) (0)
- 1314 RECURRENT MUTATIONS IN SPOP DEFINE A DISTINCT MOLECULAR CLASS OF PROSTATE CANCER (2012) (0)
- Generation of Programmable Cell Lines and Single-domain Antibodies to Study the Inflammasome Response (2017) (0)
- Symmetric Designs: Permutation Groups (1983) (0)
- The NORAD lncRNA assembles a topoisomerase complex critical for genome stability (2018) (0)
- Association de polymorphismes de la proteine kinase c zeta aux diabetes (2001) (0)
- Autism Sequencing Consortium (ASC) iPSYCH-BROAD Consortium Broad Institute Center for Common Disease Genomics (Broad-CCDG) (2021) (0)
- The Prostate Cancer Project (PC Project): Translational genomics through direct patient engagement. (2017) (0)
- Section 16. Applications Recent Developments in Computational Gene Recognition (1998) (0)
- Leading Edge Perspective The Heroes of CRISPR (2016) (0)
- A : Specific Biological Rationales for the Utility of New Sequence Data (2003) (0)
- Scientists. Excitement for a new era. (2014) (0)
- Identification of cancer driver genes based on nucleotide context (2020) (0)
- Genes, Regulation, Evolution (2003) (0)
- Compatibility rules of human enhancer and promoter sequences (2022) (0)
- Abstract OT2-05-03: The metastatic breast cancer project: A national direct-to-patient research initiative to accelerate genomics research (2016) (0)
- Novel driver genes and genomic predictors of immune infiltrates in colorectal cancer. (2016) (0)
- Table 4, Comparison of Breast Cancer Stem Cells: Probes 1, 2, and 3 (2013) (0)
- Supplementary Material 8 (2013) (0)
- A proposal to sequence the genome of the platypus, ornithorhynchus anatinus (2004) (0)
- Abstract PD8-01: The metastatic breast cancer project: Generating the clinical and genomic landscape of metastatic breast cancer through patient-partnered research (2020) (0)
- Figure 3, Heat Map Comparisons of Differential Gene Expression (2013) (0)
- Abstract 916: BRCA1 mutations impair breast epithelial differentiation through upregulation of the transcriptional repressor Slug (2011) (0)
- hypermutability with distinct patterns of DNA breakage and rearrangement-induced Somatic rearrangements across cancer reveal classes of samples Material Supplemental (2013) (0)
- Recall by genotype and cascade screening for familial hypercholesterolemia in a population-based biobank from Estonia (2018) (0)
- Lec 15 I MIT 7.012 Introduction to Biology, Fall 2004 (2008) (0)
- Sabeti Positive Natural Selection in the Human Lineage (2012) (0)
- Trekking Through The Human Genome : An Individualized Laboratory Project (2007) (0)
- Abstract OT-18-01: The metastatic breast cancer project: Generating the clinical and genomic landscape of metastatic breast cancer through patient-partnered research (2021) (0)
- Erratum to “Pathogen discovery from human tissue by sequence-based computational subtraction” ☆: [Genomics 81 (2003) 329–335]☆ (2003) (0)
- The Case for Selection at CCR5-Δ32 The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters (2005) (0)
- Symmetric Designs: DIFFERENCE SETS (1983) (0)
- Mitochondrial Diseases: Gene Mapping and Gene Therapy Minireview (1990) (0)
- A structural variation reference for medical and population genetics (2020) (0)
- Software availability [letter; comment] (1995) (0)
- Figure 5, Known Small Molecules Inhibitors of Breast Cancer Stem Cells (2013) (0)
- Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial (2018) (0)
- Conserved word-pair templates are associated with significant changes in gene expression (2011) (0)
- Symmetric Designs: REFERENCES (1983) (0)
- Introduction to Biology (2004) (0)
- erythrocyte size and number Cyclin D 3 coordinates the cell cycle during differentiation to regulate Material Supplemental (2012) (0)
- Abstract 1139: Complete characterization of prostate cancer genomes by massively parallel sequencing (2010) (0)
- THE P53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA (2014) (0)
- Massively parallel base editing to map variant effects in human hematopoiesis (2023) (0)
- Abstract B130: The intratumoral heterogeneity of glioblastoma suggests a pivotal role for clonal evolution. (2013) (0)
- Sibpair Collection Strategies in NIDDM (1996) (0)
- TRANSPLANTATION Systematic identi fi cation of personal tumor-speci fi c neoantigens in chronic lymphocytic leukemia (2014) (0)
- An integrated BAC/PAC molecular cytogenetic resource for human genetics: Applications to disease (1996) (0)
- microreads ALLPATHS : De novo assembly of whole-genome shotgun Material Supplemental (2008) (0)
- Symmetric Designs: Preface (1983) (0)
- Tool Juicebox Provides a Visua lization System for HiC Contact Maps with Unlimited Zoom Graphical (0)
- Sequencing a genome by walking with clone-end sequences (abstract): a mathematical analysis (2000) (0)
- Mining data from 1000 genomes to identify the causal variant in regions under positive selection (2010) (0)
- Speeding the Search for a Cure : Using Dynamic Work Design to Improve Genetic Sequencing (2016) (0)
- Scheme 1, Synthesis of the Probe (CID49843203/ML239) (2013) (0)
- High-throughput genomic analysis of small-cell lung cancer: allelotyping using Affymetrix HuSNP arrays (2001) (0)
- Diabetes resistance in the BB rat maps to a body weight regulator on chromosome 2. (1999) (0)
- Letter from Eric Lander to Paul B. Ferrara, George Sensabaugh, and C. Thomas Caskey (1991) (0)
- A genome-wide scan in a canadian inflammatory bowel disease (IBD) population reveals two novel susceptibility loci (2000) (0)
- Whole Genome Sequencing of Indolent CLL Reveals Novel Structural Rearrangements (2014) (0)
- A patient-driven clinicogenomic partnership for metastatic prostate cancer (2022) (0)
- Figure 4, Heat Map Comparisons of Differential Gene Expression (2013) (0)
- Abstract LB-265: Mutations in BRCA1 impair breast epithelial differentiation through the transcriptional repressor Slug (2010) (0)
- Figure 1, Stability Data for the Probe (CID 49835877/ML239) in PBS Plus Acetonitrile Over 48 Hours (2013) (0)
- Software availability. (1995) (0)
- Human knockouts and phenotypic analysis 1 in a cohort with a high rate of consanguinity 2 3 (2016) (0)
- Table 3, Comparison of the Probe (ML243) to Project Criteria (2013) (0)
- M I T S l o a n S c h o o l o f M a n a g e m e n t Using Dynamic Work Design to Help Cure Cancer ₍ and other diseases (2016) (0)
- Symmetric Designs: MULTIPLIER THEOREMS (1983) (0)
- Abstract 984: Alteration of the p53 pathway is associated with subclonal tumor progression in glioblastoma (2014) (0)
- Mapping and characterization of structural variation in 17,795 human genomes (2020) (0)
- Figure 5, Dose Inhibition Assay of HMLE_sh_GFP, HMLE_sh_ECad, and HMLE_sh_Twist by the Probe (ML245) (2014) (0)
- Sub-clinical detection of gut microbial biomarkers of obesity and type 2 diabetes (2016) (0)
- genome by low-redundancy comparative sequencing An initial strategy for the systematic identification of functional elements in the human Mullikin (2005) (0)
- Figure 4, Known Small Molecules Inhibitors of Breast Cancer Stem Cells (2013) (0)
- A novel Ruminococcus gnavus clade enriched in inflammatory bowel disease patients (2017) (0)
- Table 3, Prior Art Substance Identifiers (2013) (0)
- GE-17ALTERATION OF THE p53 PATHWAY AND ANCESTRAL PROGENITORS ARE ASSOCIATED WITH TUMOR RECURRENCE IN GLIOBLASTOMA (2014) (0)
- Symmetric Designs: SYMMETRIC DESIGNS (1983) (0)
- Genetic susceptibility in a Canadian inflammatory bowel disease (IBD) population (1998) (0)
- Figure 2, Dose-dependent Activity of the Probe (ML239) in Target and Counterscreen Assays (2013) (0)
- Linkage disequilibrium at PPARG and other genes assessed with dense sets of SNPs. (2001) (0)
- Supplemental Information Locally Disordered Methylation Forms the Basis of Intratumor Methylome Variation in Chronic Lymphocytic Leukemia (2014) (0)
- Table 3, SAR of the Phenyl Group (ortho-substitution) (2014) (0)
- Resource Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells (2013) (0)
- Typing Catching Up with Courtroom Application (2006) (0)
- Taking aim at aggressive cancer cells (2009) (0)
- Figure 6, Heat Map Comparisons of Differential Gene Expression by ML245 and CID50904149 (2014) (0)
- Comprehensivemolecularcharacterization of human colon and rectal cancer (2012) (0)
- Abstract 3925: Characterization of complex chromosomal aberrations in prostate cancer from whole genome sequencing (2011) (0)
- Abstract 1084: Comprehensive genomic analysis of murine small cell lung carcinoma uncovers recurrent Pten alterations that drive tumor progression and alter tumor genome evolution. (2013) (0)
- Symmetric Designs: OPEN QUESTIONS (1983) (0)
- Circulating tumor DNA as a marker of recurrence risk in locoregional esophagogastric cancers with pathologic complete response. (2023) (0)
- Manage risk of accidental gene editing of germline (2020) (0)
- Using the HER2/CEP17 FISH Ratio to Predict Pathologic Complete Response Following Neoadjuvant Anti-HER2 Doublet Therapy in HER2+ Breast Cancer (2022) (0)
- CLO20-042: The HER2 FISH Ratio is a Predictor of Pathologic Complete Response Among Patients With HER2+ Breast Cancer Receiving Neoadjuvant Anti-HER2 Doublet Therapy Without Chemotherapy (2020) (0)
- The Risk of Corticosteroids in Community-Acquired Pneumonia. (2020) (0)
- Abstract 6696: Genomic alterations associated with early-onset and late-onset colorectal cancer (2023) (0)
- Leena Peltonen 1952–2010 (2010) (0)
- Explaining Policy Reversals: The USA Patriot Act and the Case of Terrorist Financing (2007) (0)
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Other Resources About Eric Lander
What Schools Are Affiliated With Eric Lander?
Eric Lander is affiliated with the following schools:
- University of California, Berkeley
- California Institute of Technology
- University of Oxford
- University of Southern California
- Princeton University
- Pennsylvania State University
- Baylor College of Medicine
- Massachusetts General Hospital
- Brown University
- McGill University
- Vanderbilt University
- Stanford University
- Massachusetts Institute of Technology
- Case Western Reserve University
- Harvard University
